ACTP - ECOLI - GREMLIN Contacts

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ACTP - Cation/acetate symporter ActP

UniProt:	P32705	Sequences: MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSITVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11942
Length:	549 (471)
Sequences:	11508 (7266)
Seq/√Len:	334.8

ECOLI - ACTP PUTP YIDK PANF
BACSU - YWCA OPUE YCGO YODF YHJB
HALSA - Q9HR16 Q9HP63
SULSO - Q7LX83 Q97VX6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
467_L	510_G	6.189	1.00
397_T	400_E	4.301	1.00
290_D	293_E	3.980	1.00
456_L	511_I	3.935	1.00
393_K	400_E	3.698	1.00
48_G	52_W	3.568	1.00
224_F	228_K	3.385	1.00
467_L	506_V	3.312	1.00
193_M	413_G	3.292	1.00
512_W	516_A	3.284	1.00
236_N	239_S	3.210	1.00
388_Y	396_A	3.202	1.00
463_M	514_F	3.183	1.00
510_G	514_F	3.163	1.00
226_V	318_G	3.132	1.00
514_F	518_D	3.094	1.00
457_T	518_D	3.033	1.00
464_G	511_I	3.032	1.00
471_T	506_V	2.951	1.00
459_R	518_D	2.944	1.00
403_R	407_I	2.879	1.00
399_R	403_R	2.824	1.00
460_G	515_S	2.777	1.00
180_N	183_I	2.757	1.00
449_L	511_I	2.741	1.00
138_S	147_R	2.670	1.00
189_G	417_I	2.612	1.00
319_A	343_A	2.404	1.00
407_I	411_I	2.378	1.00
61_S	68_G	2.376	1.00
201_M	287_T	2.362	1.00
70_I	205_T	2.346	1.00
289_S	293_E	2.288	1.00
127_N	291_A	2.274	1.00
41_I	45_F	2.238	1.00
145_P	462_M	2.234	1.00
236_N	240_E	2.155	1.00
459_R	463_M	2.145	1.00
62_D	67_G	2.140	1.00
396_A	400_E	2.129	1.00
463_M	510_G	2.105	1.00
457_T	460_G	2.102	1.00
453_W	456_L	2.083	1.00
446_I	461_A	2.082	1.00
239_S	243_A	2.073	1.00
186_V	190_V	2.055	1.00
44_V	48_G	2.035	1.00
94_A	341_N	2.025	1.00
141_L	456_L	2.011	1.00
136_V	450_S	1.988	1.00
393_K	396_A	1.964	1.00
457_T	515_S	1.957	1.00
86_A	168_G	1.951	1.00
218_G	363_V	1.945	1.00
455_K	516_A	1.943	1.00
460_G	514_F	1.926	1.00
470_I	474_V	1.912	1.00
385_H	389_A	1.898	1.00
414_V	418_I	1.898	1.00
293_E	296_K	1.879	1.00
130_R	139_Y	1.875	1.00
292_R	296_K	1.851	1.00
346_H	350_A	1.846	1.00
388_Y	404_V	1.840	1.00
509_L	513_F	1.838	1.00
220_S	224_F	1.829	1.00
65_T	68_G	1.820	1.00
142_K	145_P	1.810	1.00
239_S	242_M	1.806	1.00
389_A	401_E	1.800	1.00
248_G	252_M	1.798	1.00
449_L	508_F	1.798	1.00
199_G	203_A	1.795	1.00
323_V	350_A	1.783	1.00
42_F	46_T	1.778	1.00
292_R	295_R	1.775	1.00
403_R	406_K	1.774	1.00
453_W	516_A	1.761	1.00
192_M	372_V	1.759	1.00
49_I	210_I	1.755	1.00
74_Q	209_I	1.752	1.00
235_N	239_S	1.736	1.00
460_G	464_G	1.715	1.00
400_E	403_R	1.696	1.00
383_V	387_L	1.664	1.00
463_M	467_L	1.662	1.00
383_V	408_T	1.652	1.00
467_L	471_T	1.644	1.00
453_W	512_W	1.638	1.00
72_G	293_E	1.633	1.00
250_D	253_K	1.632	1.00
182_H	421_V	1.619	1.00
240_E	243_A	1.602	1.00
388_Y	393_K	1.600	1.00
358_G	362_A	1.572	1.00
455_K	519_N	1.563	1.00
190_V	194_M	1.534	1.00
55_K	58_R	1.534	1.00
77_L	209_I	1.532	1.00
376_T	413_G	1.517	1.00
171_K	339_G	1.517	1.00
505_T	509_L	1.508	1.00
388_Y	400_E	1.487	1.00
142_K	458_T	1.472	1.00
36_I	40_L	1.471	1.00
121_I	448_L	1.455	1.00
135_D	386_D	1.426	1.00
267_L	270_G	1.415	1.00
170_G	185_V	1.411	1.00
75_N	288_V	1.399	1.00
379_G	412_L	1.396	1.00
153_G	469_L	1.393	1.00
402_L	406_K	1.386	1.00
40_L	44_V	1.379	1.00
183_I	187_L	1.376	1.00
233_S	236_N	1.367	1.00
135_D	385_H	1.347	1.00
64_Y	405_S	1.343	1.00
189_G	413_G	1.338	1.00
208_Q	284_R	1.326	1.00
396_A	401_E	1.313	1.00
263_S	267_L	1.311	1.00
185_V	417_I	1.300	1.00
230_V	237_L	1.299	1.00
35_A	355_L	1.292	1.00
183_I	186_V	1.286	1.00
138_S	143_Q	1.285	1.00
234_F	238_F	1.279	1.00
140_R	450_S	1.275	1.00
186_V	417_I	1.275	1.00
266_S	269_L	1.265	1.00
45_F	49_I	1.262	1.00
192_M	369_L	1.258	1.00
59_S	62_D	1.254	1.00
207_V	373_A	1.253	1.00
46_T	210_I	1.250	1.00
37_I	40_L	1.247	1.00
37_I	41_I	1.246	1.00
383_V	388_Y	1.239	1.00
458_T	462_M	1.233	1.00
132_T	381_S	1.230	1.00
455_K	520_S	1.228	1.00
152_C	156_V	1.223	1.00
506_V	510_G	1.219	1.00
76_G	300_Y	1.219	1.00
457_T	514_F	1.211	1.00
152_C	387_L	1.202	1.00
457_T	519_N	1.197	1.00
400_E	404_V	1.195	1.00
248_G	251_I	1.195	1.00
182_H	186_V	1.195	1.00
471_T	510_G	1.193	1.00
136_V	140_R	1.188	1.00
82_D	374_G	1.186	1.00
146_I	462_M	1.179	1.00
149_L	462_M	1.178	1.00
96_V	103_G	1.177	1.00
169_A	188_V	1.176	1.00
138_S	390_N	1.175	1.00
505_T	508_F	1.174	1.00
508_F	512_W	1.172	1.00
240_E	321_M	1.161	1.00
145_P	149_L	1.155	1.00
174_E	181_Y	1.153	1.00
66_A	201_M	1.152	1.00
166_M	189_G	1.149	1.00
474_V	478_L	1.148	1.00
48_G	51_Y	1.146	1.00
268_G	271_L	1.141	1.00
78_A	374_G	1.141	1.00
459_R	514_F	1.140	1.00
52_W	56_R	1.140	1.00
150_S	465_G	1.134	1.00
404_V	408_T	1.132	1.00
104_L	108_L	1.131	1.00
446_I	465_G	1.129	1.00
213_V	217_F	1.127	1.00
217_F	221_F	1.127	1.00
392_F	396_A	1.125	1.00
464_G	468_G	1.122	1.00
398_E	401_E	1.121	1.00
47_L	51_Y	1.119	1.00
225_M	229_H	1.116	1.00
229_H	322_L	1.114	1.00
186_V	421_V	1.113	1.00
162_L	416_A	1.104	1.00
384_S	405_S	1.098	1.00
34_Q	37_I	1.098	1.00
466_W	470_I	1.096	1.00
456_L	515_S	1.093	1.00
61_S	129_G	1.091	1.00
396_A	404_V	1.090	1.00
179_L	184_A	1.082	1.00
221_F	356_F	1.078	1.00
147_R	386_D	1.073	1.00
249_V	253_K	1.073	1.00
208_Q	373_A	1.065	1.00
384_S	404_V	1.065	1.00
345_V	348_A	1.063	1.00
242_M	245_H	1.060	1.00
80_A	304_F	1.059	1.00
510_G	513_F	1.059	1.00
502_F	505_T	1.057	1.00
116_I	120_L	1.056	1.00
66_A	70_I	1.056	1.00
47_L	50_T	1.053	1.00
431_M	435_A	1.051	1.00
264_A	267_L	1.050	1.00
238_F	242_M	1.042	1.00
146_I	461_A	1.042	1.00
500_A	504_I	1.042	1.00
221_F	225_M	1.040	1.00
235_N	238_F	1.033	1.00
408_T	411_I	1.031	1.00
153_G	465_G	1.030	1.00
57_V	62_D	1.029	1.00
459_R	517_T	1.026	1.00
45_F	210_I	1.025	1.00
72_G	76_G	1.020	1.00
192_M	373_A	1.020	1.00
346_H	349_N	1.018	1.00
42_F	369_L	1.017	1.00
211_K	373_A	1.017	1.00
195_Y	369_L	1.008	1.00
348_A	360_I	1.007	1.00
34_Q	38_M	1.006	1.00
464_G	507_A	1.006	1.00
267_L	271_L	1.005	1.00
163_I	419_L	1.002	1.00
456_L	460_G	1.002	1.00
195_Y	373_A	1.000	1.00
122_A	125_L	0.994	1.00
252_M	255_G	0.992	1.00
442_C	507_A	0.990	1.00
197_L	410_L	0.989	1.00
45_F	48_G	0.985	1.00
237_L	318_G	0.985	1.00
260_D	264_A	0.980	1.00
98_T	340_N	0.980	1.00
339_G	342_M	0.979	1.00
111_L	306_G	0.975	1.00
449_L	456_L	0.974	1.00
429_A	433_G	0.962	1.00
468_G	472_A	0.960	1.00
223_A	311_L	0.960	1.00
166_M	185_V	0.959	1.00
389_A	394_K	0.958	1.00
145_P	458_T	0.954	1.00
414_V	417_I	0.949	1.00
455_K	521_A	0.942	1.00
208_Q	374_G	0.940	1.00
383_V	412_L	0.935	1.00
434_L	476_M	0.934	1.00
446_I	507_A	0.934	1.00
427_N	430_F	0.927	1.00
237_L	241_A	0.926	1.00
137_A	150_S	0.921	1.00
124_R	127_N	0.919	1.00
380_A	384_S	0.917	1.00
249_V	252_M	0.913	1.00
392_F	395_G	0.910	1.00
250_D	254_P	0.909	1.00
82_D	208_Q	0.908	1.00
521_A	524_A	0.904	1.00
264_A	271_L	0.902	1.00
78_A	205_T	0.901	1.00
145_P	148_I	0.893	1.00
227_M	233_S	0.893	1.00
72_G	296_K	0.889	1.00
95_L	99_S	0.889	1.00
318_G	322_L	0.888	1.00
64_Y	381_S	0.887	1.00
123_E	295_R	0.886	1.00
288_V	294_A	0.886	1.00
337_I	340_N	0.884	1.00
261_P	264_A	0.880	1.00
348_A	357_L	0.878	1.00
449_L	512_W	0.877	1.00
39_F	43_V	0.876	1.00
78_A	81_G	0.872	1.00
43_V	46_T	0.871	1.00
71_T	293_E	0.871	1.00
140_R	453_W	0.869	1.00
261_P	266_S	0.868	1.00
388_Y	394_K	0.868	1.00
405_S	409_V	0.865	1.00
450_S	461_A	0.864	1.00
370_A	373_A	0.863	1.00
411_I	415_I	0.862	1.00
261_P	265_L	0.859	1.00
74_Q	205_T	0.859	1.00
148_I	391_V	0.856	1.00
460_G	463_M	0.852	1.00
226_V	229_H	0.851	1.00
428_I	432_V	0.846	1.00
433_G	437_A	0.846	1.00
240_E	244_V	0.845	1.00
229_H	351_V	0.845	1.00
141_L	450_S	0.845	1.00
137_A	146_I	0.844	1.00
263_S	266_S	0.842	1.00
388_Y	392_F	0.839	1.00
101_Y	317_F	0.839	1.00
453_W	460_G	0.836	1.00
507_A	511_I	0.836	1.00
155_L	383_V	0.836	1.00
149_L	465_G	0.835	1.00
39_F	365_F	0.834	1.00
247_K	250_D	0.833	1.00
445_P	508_F	0.833	1.00
179_L	187_L	0.831	1.00
519_N	522_E	0.830	1.00
54_S	57_V	0.830	1.00
299_F	303_G	0.830	1.00
453_W	515_S	0.829	1.00
268_G	272_M	0.828	1.00
228_K	234_F	0.828	1.00
85_S	161_Y	0.824	1.00
471_T	474_V	0.822	1.00
260_D	263_S	0.821	1.00
141_L	511_I	0.820	1.00
513_F	516_A	0.820	1.00
207_V	211_K	0.817	1.00
225_M	228_K	0.816	1.00
72_G	300_Y	0.815	1.00
86_A	368_I	0.814	1.00
211_K	366_A	0.814	1.00
474_V	477_I	0.814	1.00
42_F	366_A	0.813	1.00
262_I	266_S	0.810	1.00
248_G	254_P	0.807	1.00
461_A	468_G	0.804	1.00
377_L	380_A	0.804	1.00
174_E	178_G	0.803	1.00
319_A	347_L	0.803	1.00
219_A	312_T	0.802	1.00
471_T	475_L	0.801	1.00
185_V	420_G	0.799	1.00
96_V	317_F	0.798	1.00
222_M	226_V	0.798	1.00
52_W	55_K	0.796	1.00
506_V	509_L	0.796	1.00
204_T	207_V	0.795	1.00
231_G	236_N	0.794	1.00
249_V	254_P	0.794	1.00
251_I	255_G	0.793	1.00
81_G	284_R	0.790	1.00
38_M	355_L	0.790	1.00
512_W	515_S	0.790	1.00
462_M	466_W	0.790	1.00
315_I	347_L	0.788	1.00
251_I	254_P	0.786	1.00
237_L	321_M	0.786	1.00
352_G	356_F	0.784	1.00
52_W	206_W	0.783	1.00
46_T	50_T	0.782	1.00
134_A	150_S	0.780	1.00
78_A	82_D	0.778	1.00
237_L	240_E	0.777	1.00
457_T	520_S	0.777	1.00
465_G	468_G	0.772	1.00
181_Y	185_V	0.771	1.00
238_F	241_A	0.771	1.00
468_G	507_A	0.769	1.00
418_I	422_L	0.769	1.00
480_P	483_W	0.767	1.00
453_W	457_T	0.766	1.00
35_A	38_M	0.766	1.00
459_R	519_N	0.765	1.00
234_F	237_L	0.765	1.00
342_M	346_H	0.763	1.00
111_L	302_T	0.763	1.00
467_L	514_F	0.762	1.00
355_L	359_F	0.761	1.00
53_A	57_V	0.761	1.00
161_Y	279_P	0.759	1.00
97_F	337_I	0.758	1.00
468_G	471_T	0.757	1.00
126_R	291_A	0.757	1.00
66_A	287_T	0.757	1.00
503_S	507_A	0.757	1.00
78_A	284_R	0.756	1.00
383_V	404_V	0.756	1.00
119_F	299_F	0.752	1.00
77_L	212_A	0.752	1.00
155_L	379_G	0.752	1.00
264_A	268_G	0.751	1.00
97_F	325_A	0.750	1.00
170_G	181_Y	0.747	0.99
211_K	369_L	0.747	0.99
195_Y	211_K	0.745	0.99
109_G	113_G	0.745	0.99
201_M	205_T	0.743	0.99
499_P	503_S	0.741	0.99
508_F	511_I	0.739	0.99
35_A	357_L	0.738	0.99
260_D	267_L	0.738	0.99
513_F	517_T	0.736	0.99
242_M	246_P	0.736	0.99
41_I	48_G	0.735	0.99
449_L	453_W	0.735	0.99
501_L	505_T	0.733	0.99
464_G	467_L	0.732	0.99
115_P	119_F	0.728	0.99
517_T	520_S	0.725	0.99
51_Y	54_S	0.725	0.99
206_W	209_I	0.725	0.99
259_K	263_S	0.725	0.99
135_D	139_Y	0.722	0.99
51_Y	198_F	0.722	0.99
204_T	374_G	0.721	0.99
429_A	432_V	0.720	0.99
143_Q	458_T	0.719	0.99
171_K	174_E	0.719	0.99
418_I	421_V	0.717	0.99
216_L	220_S	0.715	0.99
148_I	152_C	0.715	0.99
88_S	309_Y	0.713	0.99
409_V	413_G	0.713	0.99
302_T	306_G	0.713	0.99
520_S	523_G	0.713	0.99
509_L	512_W	0.713	0.99
122_A	294_A	0.711	0.99
256_G	259_K	0.710	0.99
142_K	524_A	0.709	0.99
89_F	219_A	0.709	0.99
195_Y	203_A	0.708	0.99
142_K	522_E	0.707	0.99
195_Y	370_A	0.707	0.99
384_S	401_E	0.706	0.99
244_V	320_I	0.706	0.99
248_G	253_K	0.705	0.99
57_V	402_L	0.704	0.99
475_L	502_F	0.703	0.99
157_V	438_I	0.703	0.99
54_S	198_F	0.702	0.99
184_A	188_V	0.702	0.99
222_M	344_A	0.699	0.99
257_L	260_D	0.699	0.99
53_A	206_W	0.696	0.99
211_K	371_V	0.696	0.99
60_R	64_Y	0.695	0.99
389_A	398_E	0.695	0.99
106_Y	109_G	0.693	0.99
169_A	368_I	0.692	0.99
227_M	231_G	0.692	0.99
518_D	521_A	0.691	0.99
456_L	464_G	0.690	0.99
50_T	53_A	0.686	0.99
171_K	341_N	0.684	0.99
38_M	358_G	0.681	0.99
174_E	180_N	0.676	0.99
51_Y	55_K	0.674	0.99
70_I	75_N	0.673	0.99
227_M	314_I	0.673	0.99
380_A	408_T	0.672	0.99
165_Q	372_V	0.671	0.99
46_T	51_Y	0.670	0.99
73_F	209_I	0.669	0.99
121_I	125_L	0.668	0.99
407_I	410_L	0.667	0.99
132_T	386_D	0.665	0.99
303_G	307_Y	0.665	0.99
167_V	171_K	0.664	0.99
196_V	373_A	0.663	0.99
433_G	436_F	0.662	0.99
504_I	507_A	0.662	0.99
258_V	261_P	0.662	0.99
149_L	466_W	0.661	0.99
463_M	466_W	0.660	0.99
320_I	343_A	0.659	0.99
38_M	362_A	0.658	0.99
478_L	482_I	0.652	0.99
89_F	360_I	0.650	0.99
288_V	293_E	0.649	0.99
241_A	317_F	0.649	0.99
42_F	50_T	0.648	0.99
337_I	346_H	0.647	0.99
63_Y	409_V	0.647	0.99
245_H	248_G	0.647	0.99
254_P	257_L	0.646	0.99
401_E	405_S	0.642	0.98
131_Y	135_D	0.642	0.98
220_S	223_A	0.642	0.98
417_I	421_V	0.641	0.98
337_I	342_M	0.640	0.98
137_A	446_I	0.640	0.98
37_I	44_V	0.639	0.98
107_S	114_W	0.639	0.98
471_T	503_S	0.639	0.98
326_N	337_I	0.639	0.98
62_D	202_L	0.639	0.98
141_L	449_L	0.638	0.98
186_V	414_V	0.638	0.98
426_Q	430_F	0.638	0.98
459_R	462_M	0.636	0.98
391_V	394_K	0.635	0.98
211_K	370_A	0.632	0.98
380_A	409_V	0.632	0.98
461_A	464_G	0.632	0.98
47_L	194_M	0.630	0.98
241_A	245_H	0.629	0.98
81_G	211_K	0.629	0.98
371_V	375_L	0.628	0.98
221_F	224_F	0.628	0.98
71_T	74_Q	0.627	0.98
193_M	410_L	0.627	0.98
274_G	279_P	0.625	0.98
336_L	339_G	0.625	0.98
70_I	287_T	0.624	0.98
146_I	458_T	0.623	0.98
142_K	146_I	0.621	0.98
375_L	378_A	0.621	0.98
166_M	203_A	0.621	0.98
233_S	237_L	0.621	0.98
236_N	321_M	0.620	0.98
323_V	346_H	0.620	0.98
78_A	208_Q	0.619	0.98
432_V	436_F	0.618	0.98
223_A	314_I	0.617	0.98
63_Y	406_K	0.617	0.98
73_F	77_L	0.617	0.98
106_Y	110_F	0.614	0.98
261_P	267_L	0.612	0.98
469_L	473_V	0.611	0.98
74_Q	206_W	0.609	0.98
514_F	517_T	0.608	0.98
202_L	206_W	0.608	0.98
228_K	233_S	0.608	0.98
112_V	269_L	0.606	0.98
83_Y	436_F	0.606	0.98
456_L	461_A	0.606	0.98
259_K	262_I	0.605	0.98
165_Q	371_V	0.605	0.98
296_K	300_Y	0.604	0.98
267_L	272_M	0.603	0.98
313_F	317_F	0.602	0.98
134_A	154_S	0.602	0.98
123_E	291_A	0.602	0.98
173_I	184_A	0.601	0.98
85_S	89_F	0.600	0.98
171_K	175_L	0.599	0.98
428_I	431_M	0.599	0.98
241_A	244_V	0.599	0.98
494_F	502_F	0.598	0.98
444_F	448_L	0.597	0.98
109_G	118_L	0.596	0.98
322_L	347_L	0.596	0.98
80_A	308_F	0.596	0.98
95_L	98_T	0.596	0.98
342_M	345_V	0.595	0.97
467_L	470_I	0.595	0.97
347_L	351_V	0.592	0.97
280_H	283_M	0.592	0.97
107_S	110_F	0.590	0.97
159_A	419_L	0.590	0.97
43_V	47_L	0.590	0.97
83_Y	110_F	0.589	0.97
445_P	511_I	0.586	0.97
457_T	461_A	0.584	0.97
305_M	309_Y	0.583	0.97
455_K	515_S	0.583	0.97
81_G	212_A	0.583	0.97
114_W	117_I	0.582	0.97
123_E	127_N	0.582	0.97
219_A	311_L	0.582	0.97
164_A	435_A	0.581	0.97
120_L	124_R	0.581	0.97
193_M	197_L	0.581	0.97
354_N	357_L	0.580	0.97
472_A	503_S	0.577	0.97
265_L	272_M	0.577	0.97
369_L	373_A	0.574	0.97
388_Y	391_V	0.574	0.97
455_K	459_R	0.574	0.97
458_T	461_A	0.573	0.97
35_A	358_G	0.573	0.97
230_V	236_N	0.571	0.97
60_R	63_Y	0.570	0.97
80_A	212_A	0.570	0.97
91_G	161_Y	0.570	0.97
217_F	220_S	0.569	0.97
384_S	408_T	0.569	0.97
230_V	321_M	0.569	0.97
148_I	151_A	0.569	0.97
315_I	344_A	0.568	0.97
227_M	234_F	0.567	0.97
154_S	382_A	0.566	0.97
498_Y	502_F	0.565	0.97
296_K	299_F	0.564	0.97
195_Y	199_G	0.564	0.97
320_I	324_G	0.563	0.96
46_T	53_A	0.563	0.96
141_L	461_A	0.563	0.96
60_R	401_E	0.562	0.96
75_N	78_A	0.562	0.96
113_G	117_I	0.562	0.96
189_G	420_G	0.561	0.96
175_L	345_V	0.560	0.96
120_L	123_E	0.560	0.96
227_M	237_L	0.560	0.96
453_W	517_T	0.559	0.96
161_Y	375_L	0.559	0.96
157_V	439_A	0.558	0.96
231_G	234_F	0.558	0.96
61_S	398_E	0.558	0.96
384_S	388_Y	0.557	0.96
496_Y	500_A	0.555	0.96
87_A	436_F	0.555	0.96
322_L	351_V	0.554	0.96
204_T	284_R	0.553	0.96
175_L	342_M	0.553	0.96
352_G	360_I	0.552	0.96
76_G	80_A	0.552	0.96
410_L	413_G	0.551	0.96
245_H	249_V	0.551	0.96
432_V	435_A	0.550	0.96
208_Q	370_A	0.549	0.96
325_A	338_G	0.549	0.96
162_L	372_V	0.549	0.96
479_G	483_W	0.549	0.96
42_F	211_K	0.548	0.96
476_M	481_T	0.545	0.96
476_M	499_P	0.544	0.96
415_I	418_I	0.542	0.96
60_R	398_E	0.542	0.96
42_F	214_L	0.542	0.96
426_Q	431_M	0.541	0.96
111_L	114_W	0.541	0.96
180_N	184_A	0.541	0.96
325_A	337_I	0.540	0.96
241_A	247_K	0.540	0.96
266_S	501_L	0.539	0.96
92_I	96_V	0.537	0.95
115_P	298_V	0.536	0.95
380_A	405_S	0.536	0.95
266_S	271_L	0.535	0.95
504_I	508_F	0.534	0.95
97_F	343_A	0.534	0.95
56_R	202_L	0.534	0.95
289_S	292_R	0.532	0.95
83_Y	305_M	0.531	0.95
82_D	280_H	0.531	0.95
160_L	435_A	0.530	0.95
428_I	433_G	0.530	0.95
153_G	442_C	0.530	0.95
264_A	270_G	0.530	0.95
170_G	184_A	0.528	0.95
113_G	116_I	0.528	0.95
53_A	56_R	0.527	0.95
460_G	510_G	0.527	0.95
441_S	445_P	0.526	0.95
401_E	404_V	0.526	0.95
173_I	177_F	0.526	0.95
185_V	188_V	0.525	0.95
285_F	298_V	0.525	0.95
470_I	473_V	0.525	0.95
197_L	403_R	0.524	0.95
460_G	507_A	0.524	0.95
423_F	426_Q	0.524	0.95
417_I	420_G	0.523	0.95
204_T	377_L	0.523	0.95
82_D	284_R	0.522	0.95
393_K	398_E	0.521	0.95
349_N	357_L	0.521	0.95
186_V	189_G	0.520	0.95
167_V	181_Y	0.520	0.95
131_Y	385_H	0.519	0.95
455_K	458_T	0.518	0.94
166_M	416_A	0.518	0.94
205_T	208_Q	0.516	0.94
185_V	189_G	0.516	0.94
475_L	479_G	0.516	0.94
497_E	501_L	0.514	0.94
228_K	231_G	0.514	0.94
317_F	321_M	0.514	0.94
376_T	409_V	0.514	0.94
148_I	387_L	0.514	0.94
83_Y	432_V	0.513	0.94
263_S	268_G	0.513	0.94
299_F	302_T	0.513	0.94
34_Q	354_N	0.513	0.94
179_L	183_I	0.513	0.94
105_I	109_G	0.512	0.94
89_F	94_A	0.512	0.94
111_L	115_P	0.511	0.94
353_G	356_F	0.511	0.94
122_A	291_A	0.511	0.94
222_M	348_A	0.509	0.94
154_S	443_N	0.509	0.94
496_Y	499_P	0.508	0.94
220_S	307_Y	0.507	0.94
269_L	272_M	0.507	0.94
222_M	360_I	0.506	0.94
321_M	324_G	0.506	0.94
468_G	510_G	0.506	0.94
428_I	436_F	0.505	0.94
230_V	233_S	0.505	0.94
109_G	112_V	0.504	0.94
273_F	444_F	0.504	0.94
291_A	295_R	0.504	0.94
226_V	351_V	0.503	0.94
165_Q	375_L	0.501	0.93
56_R	69_N	0.500	0.93
133_F	447_I	0.500	0.93
473_V	477_I	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2xq2A	2	0.8725	100	0.309	Contact Map
3dh4A	3	0.8324	100	0.351	Contact Map
3l1lA	2	0.7432	99.4	0.87	Contact Map
3giaA	1	0.7705	99.3	0.873	Contact Map
4djkA	2	0.7577	99.1	0.888	Contact Map
2jlnA	1	0.7668	98.9	0.896	Contact Map
4wgvA	2	0.6794	98.8	0.898	Contact Map
4c7rA	3	0.8506	97.9	0.921	Contact Map
2wswA	3	0.7851	97.2	0.932	Contact Map
4xp4A	1	0.7978	94	0.947	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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