YJCC - ECOLI - GREMLIN Contacts

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YJCC - Putative cyclic-di-GMP phosphodiesterase YjcC

UniProt:	P32701	Sequences: MSHRARHQLLALPGIIFLVLFPIILSLWIAFLWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDNHFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPLFWSEVMSDDPTLQWGVYDTVTKTFFSLSKEASAATFSPLIHLKDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLITHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQIMNPAEFIPLAEKEGMIEQITDYVIDNVFRDLGDYLATHADRYVSINLSASDFHTSRLIARINQKTEQYAVRPQQIKFEVTEHAFLDVDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEEQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11938
Length:	528 (444)
Sequences:	19369 (15281)
Seq/√Len:	725.2

ECOLI - YJCC YEGE DOSP YLIE YFGF YFEA GMR YLAB YHJK CSRD RTN YCGG ADRB BLUF YAHA
BACSU - YKOW YKUI

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
302_A	512_F	3.972	1.00
294_I	498_C	3.803	1.00
95_E	99_A	3.489	1.00
336_D	375_R	3.431	1.00
377_N	415_A	3.209	1.00
446_K	450_E	3.011	1.00
335_T	366_D	2.960	1.00
340_D	382_Q	2.895	1.00
285_C	309_P	2.877	1.00
413_R	440_D	2.824	1.00
504_A	507_M	2.798	1.00
267_N	320_E	2.765	1.00
288_Y	345_D	2.752	1.00
391_K	441_I	2.710	1.00
293_D	296_T	2.619	1.00
350_L	389_Q	2.528	1.00
167_S	170_P	2.512	1.00
489_W	493_R	2.508	1.00
347_G	351_A	2.463	1.00
470_H	496_R	2.435	1.00
484_E	488_N	2.371	1.00
274_K	310_G	2.310	1.00
337_Y	341_N	2.227	1.00
487_V	503_F	2.216	1.00
111_A	185_F	2.187	1.00
345_D	509_P	2.163	1.00
463_E	471_S	2.148	1.00
341_N	344_R	2.107	1.00
420_A	441_I	2.097	1.00
435_K	458_S	2.075	1.00
481_V	498_C	2.067	1.00
309_P	315_I	2.031	1.00
277_R	281_K	2.002	1.00
106_C	110_I	1.982	1.00
130_S	228_V	1.974	1.00
310_G	314_Q	1.963	1.00
325_A	334_I	1.923	1.00
115_G	232_Y	1.914	1.00
343_F	379_K	1.906	1.00
459_H	489_W	1.904	1.00
306_L	338_V	1.900	1.00
285_C	315_I	1.888	1.00
268_Y	327_K	1.887	1.00
341_N	345_D	1.879	1.00
362_L	372_L	1.864	1.00
463_E	493_R	1.834	1.00
508_P	511_V	1.816	1.00
287_Y	508_P	1.814	1.00
483_T	486_Q	1.802	1.00
291_I	497_Y	1.786	1.00
386_R	389_Q	1.786	1.00
487_V	498_C	1.772	1.00
86_I	90_Y	1.763	1.00
340_D	379_K	1.760	1.00
132_Y	200_I	1.754	1.00
282_H	341_N	1.736	1.00
231_S	234_R	1.723	1.00
132_Y	224_I	1.716	1.00
357_Y	418_E	1.711	1.00
346_L	385_V	1.706	1.00
379_K	383_Y	1.701	1.00
487_V	491_R	1.696	1.00
409_I	419_V	1.689	1.00
391_K	420_A	1.689	1.00
110_I	114_N	1.683	1.00
291_I	441_I	1.662	1.00
441_I	477_I	1.653	1.00
453_T	459_H	1.653	1.00
292_I	503_F	1.652	1.00
345_D	349_Y	1.650	1.00
286_L	338_V	1.641	1.00
463_E	467_E	1.639	1.00
340_D	383_Y	1.637	1.00
249_A	255_L	1.628	1.00
418_E	440_D	1.625	1.00
153_Y	156_V	1.618	1.00
484_E	502_F	1.605	1.00
442_L	469_A	1.585	1.00
246_A	255_L	1.584	1.00
287_Y	315_I	1.573	1.00
487_V	502_F	1.534	1.00
357_Y	391_K	1.532	1.00
157_I	211_G	1.520	1.00
212_Y	217_V	1.518	1.00
453_T	485_E	1.517	1.00
310_G	313_G	1.514	1.00
466_I	495_V	1.514	1.00
300_I	497_Y	1.512	1.00
380_T	417_Y	1.512	1.00
284_L	306_L	1.498	1.00
475_K	497_Y	1.497	1.00
466_I	493_R	1.496	1.00
137_T	223_P	1.491	1.00
475_K	496_R	1.488	1.00
352_T	513_M	1.476	1.00
100_R	178_D	1.475	1.00
291_I	391_K	1.458	1.00
143_Y	151_G	1.444	1.00
306_L	334_I	1.442	1.00
283_Q	310_G	1.434	1.00
138_P	251_I	1.430	1.00
349_Y	509_P	1.427	1.00
226_A	256_V	1.424	1.00
157_I	160_L	1.423	1.00
154_V	220_T	1.423	1.00
114_N	177_Y	1.418	1.00
501_W	506_A	1.418	1.00
114_N	117_T	1.407	1.00
441_I	475_K	1.395	1.00
95_E	104_F	1.388	1.00
286_L	337_Y	1.387	1.00
507_M	515_W	1.383	1.00
362_L	392_F	1.374	1.00
435_K	451_T	1.372	1.00
421_I	439_V	1.369	1.00
179_T	185_F	1.363	1.00
350_L	386_R	1.360	1.00
378_Q	382_Q	1.358	1.00
344_R	383_Y	1.342	1.00
94_N	98_Y	1.341	1.00
92_Y	96_L	1.337	1.00
453_T	489_W	1.334	1.00
348_D	352_T	1.330	1.00
160_L	163_S	1.329	1.00
291_I	301_G	1.328	1.00
130_S	196_F	1.316	1.00
86_I	89_G	1.314	1.00
166_M	176_V	1.314	1.00
153_Y	214_Y	1.305	1.00
114_N	175_G	1.293	1.00
299_C	515_W	1.291	1.00
342_V	358_V	1.286	1.00
116_Y	232_Y	1.282	1.00
380_T	387_P	1.279	1.00
158_N	207_V	1.278	1.00
245_F	248_P	1.275	1.00
406_T	410_L	1.267	1.00
446_K	480_G	1.266	1.00
332_E	369_T	1.264	1.00
511_V	514_Q	1.255	1.00
111_A	177_Y	1.252	1.00
375_R	379_K	1.251	1.00
469_A	476_T	1.244	1.00
188_S	199_L	1.234	1.00
283_Q	308_W	1.227	1.00
267_N	313_G	1.226	1.00
488_N	491_R	1.226	1.00
197_S	256_V	1.224	1.00
346_L	358_V	1.224	1.00
377_N	411_A	1.221	1.00
345_D	348_D	1.220	1.00
478_A	495_V	1.219	1.00
452_L	489_W	1.203	1.00
274_K	313_G	1.202	1.00
234_R	238_H	1.198	1.00
498_C	503_F	1.197	1.00
238_H	262_L	1.188	1.00
293_D	300_I	1.185	1.00
157_I	161_F	1.182	1.00
377_N	381_E	1.179	1.00
306_L	337_Y	1.176	1.00
105_L	159_P	1.175	1.00
313_G	320_E	1.174	1.00
79_H	82_R	1.174	1.00
406_T	436_S	1.167	1.00
78_A	82_R	1.166	1.00
504_A	515_W	1.165	1.00
277_R	283_Q	1.165	1.00
293_D	298_K	1.165	1.00
245_F	255_L	1.164	1.00
138_P	141_S	1.157	1.00
134_Y	222_R	1.156	1.00
373_I	377_N	1.149	1.00
294_I	487_V	1.149	1.00
355_D	389_Q	1.148	1.00
488_N	492_K	1.145	1.00
391_K	418_E	1.142	1.00
245_F	249_A	1.141	1.00
196_F	200_I	1.138	1.00
467_E	471_S	1.136	1.00
192_S	195_T	1.135	1.00
246_A	253_G	1.133	1.00
133_Y	185_F	1.131	1.00
410_L	414_Q	1.126	1.00
297_E	491_R	1.125	1.00
206_T	209_R	1.124	1.00
349_Y	513_M	1.109	1.00
87_I	90_Y	1.108	1.00
207_V	222_R	1.103	1.00
359_S	391_K	1.100	1.00
197_S	201_H	1.100	1.00
439_V	474_L	1.093	1.00
270_S	274_K	1.090	1.00
507_M	511_V	1.089	1.00
484_E	487_V	1.084	1.00
453_T	483_T	1.084	1.00
200_I	226_A	1.082	1.00
291_I	359_S	1.074	1.00
376_I	412_F	1.072	1.00
373_I	411_A	1.070	1.00
452_L	462_A	1.070	1.00
204_D	254_S	1.069	1.00
441_I	497_Y	1.064	1.00
136_D	158_N	1.064	1.00
153_Y	157_I	1.063	1.00
75_C	78_A	1.058	1.00
271_P	324_L	1.058	1.00
455_H	458_S	1.056	1.00
201_H	205_L	1.056	1.00
347_G	350_L	1.053	1.00
489_W	492_K	1.051	1.00
227_I	238_H	1.050	1.00
376_I	392_F	1.047	1.00
340_D	344_R	1.046	1.00
347_G	383_Y	1.045	1.00
77_P	80_Q	1.043	1.00
285_C	508_P	1.040	1.00
464_H	471_S	1.037	1.00
141_S	272_K	1.037	1.00
301_G	357_Y	1.034	1.00
364_A	397_H	1.033	1.00
346_L	350_L	1.029	1.00
118_I	189_K	1.029	1.00
72_G	82_R	1.028	1.00
460_L	471_S	1.026	1.00
204_D	224_I	1.022	1.00
404_K	408_I	1.021	1.00
99_A	110_I	1.018	1.00
284_L	337_Y	1.015	1.00
318_P	321_F	1.014	1.00
392_F	417_Y	1.009	1.00
328_E	332_E	1.006	1.00
343_F	390_I	1.006	1.00
110_I	113_V	1.005	1.00
342_V	360_I	1.004	1.00
121_A	189_K	1.002	1.00
133_Y	243_L	1.000	1.00
509_P	513_M	1.000	1.00
291_I	357_Y	0.998	1.00
165_V	206_T	0.993	1.00
98_Y	109_L	0.985	1.00
373_I	408_I	0.983	1.00
274_K	312_Q	0.980	1.00
76_T	79_H	0.978	1.00
402_V	437_L	0.971	1.00
291_I	477_I	0.970	1.00
275_L	325_A	0.968	1.00
379_K	382_Q	0.968	1.00
82_R	86_I	0.962	1.00
319_A	446_K	0.962	1.00
150_R	153_Y	0.962	1.00
98_Y	113_V	0.962	1.00
466_I	476_T	0.957	1.00
135_R	247_L	0.955	1.00
347_G	384_A	0.954	1.00
286_L	342_V	0.954	1.00
200_I	254_S	0.952	1.00
283_Q	311_E	0.952	1.00
344_R	348_D	0.950	1.00
197_S	254_S	0.950	1.00
262_L	266_Q	0.949	1.00
372_L	376_I	0.949	1.00
92_Y	95_E	0.946	1.00
165_V	202_L	0.946	1.00
208_Q	252_L	0.944	1.00
292_I	515_W	0.943	1.00
118_I	129_V	0.938	1.00
75_C	80_Q	0.937	1.00
408_I	411_A	0.937	1.00
333_Q	336_D	0.936	1.00
411_A	414_Q	0.935	1.00
161_F	211_G	0.935	1.00
85_N	88_R	0.931	1.00
313_G	316_M	0.930	1.00
310_G	316_M	0.928	1.00
477_I	497_Y	0.925	1.00
110_I	175_G	0.923	1.00
136_D	222_R	0.923	1.00
277_R	280_E	0.921	1.00
293_D	496_R	0.921	1.00
282_H	337_Y	0.920	1.00
322_I	331_I	0.920	1.00
116_Y	120_P	0.918	1.00
272_K	276_Q	0.917	1.00
295_K	496_R	0.915	1.00
166_M	170_P	0.914	1.00
156_V	160_L	0.913	1.00
143_Y	181_T	0.913	1.00
132_Y	188_S	0.913	1.00
101_D	109_L	0.905	1.00
162_W	176_V	0.905	1.00
371_R	375_R	0.904	1.00
221_K	252_L	0.901	1.00
345_D	513_M	0.901	1.00
304_A	358_V	0.899	1.00
326_E	331_I	0.899	1.00
400_L	433_N	0.899	1.00
280_E	333_Q	0.899	1.00
330_M	333_Q	0.899	1.00
339_I	379_K	0.894	1.00
234_R	237_T	0.893	1.00
401_D	404_K	0.893	1.00
98_Y	110_I	0.892	1.00
78_A	84_L	0.888	1.00
112_P	233_Q	0.887	1.00
114_N	118_I	0.882	1.00
129_V	187_L	0.882	1.00
135_R	182_K	0.880	1.00
369_T	375_R	0.879	1.00
154_V	211_G	0.879	1.00
134_Y	186_S	0.874	1.00
228_V	256_V	0.873	1.00
90_Y	94_N	0.872	1.00
275_L	284_L	0.871	1.00
212_Y	215_A	0.867	1.00
288_Y	302_A	0.866	1.00
286_L	306_L	0.865	1.00
466_I	470_H	0.862	1.00
150_R	216_T	0.858	1.00
241_N	261_W	0.858	1.00
193_A	197_S	0.855	1.00
259_L	263_R	0.855	1.00
213_L	218_Y	0.855	1.00
76_T	80_Q	0.854	1.00
83_M	86_I	0.854	1.00
336_D	379_K	0.853	1.00
303_E	361_N	0.850	1.00
407_P	411_A	0.850	1.00
453_T	486_Q	0.849	1.00
149_Q	233_Q	0.848	1.00
205_L	208_Q	0.847	1.00
164_E	206_T	0.843	1.00
276_Q	330_M	0.843	1.00
88_R	92_Y	0.841	1.00
286_L	304_A	0.841	1.00
89_G	92_Y	0.840	1.00
278_A	284_L	0.839	1.00
375_R	378_Q	0.839	1.00
311_E	314_Q	0.837	1.00
339_I	376_I	0.836	1.00
199_L	202_L	0.836	1.00
357_Y	389_Q	0.836	1.00
295_K	491_R	0.835	1.00
282_H	340_D	0.835	1.00
348_D	509_P	0.834	1.00
278_A	283_Q	0.832	1.00
207_V	211_G	0.826	1.00
72_G	75_C	0.824	1.00
166_M	186_S	0.822	1.00
374_A	411_A	0.822	1.00
217_V	277_R	0.822	1.00
302_A	356_R	0.820	1.00
339_I	360_I	0.818	1.00
272_K	328_E	0.815	1.00
336_D	340_D	0.810	1.00
200_I	204_D	0.809	1.00
374_A	378_Q	0.808	1.00
115_G	187_L	0.807	1.00
385_V	390_I	0.806	1.00
83_M	87_I	0.804	1.00
112_P	116_Y	0.804	1.00
73_Q	76_T	0.803	1.00
78_A	81_K	0.801	1.00
71_Q	75_C	0.801	1.00
143_Y	152_N	0.800	1.00
297_E	487_V	0.798	1.00
75_C	82_R	0.797	1.00
76_T	82_R	0.796	1.00
343_F	385_V	0.795	1.00
142_G	151_G	0.794	1.00
113_V	117_T	0.793	1.00
288_Y	304_A	0.792	1.00
450_E	486_Q	0.789	1.00
276_Q	333_Q	0.789	1.00
470_H	476_T	0.788	1.00
249_A	253_G	0.787	1.00
191_A	195_T	0.786	1.00
227_I	235_L	0.783	1.00
460_L	463_E	0.783	1.00
332_E	366_D	0.782	1.00
348_D	351_A	0.782	1.00
106_C	175_G	0.780	1.00
75_C	81_K	0.779	1.00
370_S	404_K	0.776	1.00
481_V	487_V	0.776	1.00
292_I	299_C	0.775	1.00
137_T	251_I	0.773	1.00
72_G	76_T	0.771	1.00
140_F	144_K	0.770	1.00
133_Y	239_F	0.767	1.00
245_F	264_I	0.765	1.00
102_N	156_V	0.763	1.00
360_I	390_I	0.762	1.00
467_E	470_H	0.761	1.00
410_L	438_N	0.759	1.00
435_K	461_I	0.759	1.00
343_F	383_Y	0.756	1.00
87_I	91_L	0.756	1.00
288_Y	509_P	0.755	1.00
226_A	254_S	0.754	1.00
481_V	490_L	0.754	1.00
196_F	228_V	0.753	1.00
138_P	272_K	0.751	1.00
418_E	475_K	0.749	1.00
304_A	342_V	0.748	1.00
75_C	79_H	0.748	1.00
200_I	224_I	0.747	1.00
77_P	82_R	0.747	1.00
449_V	452_L	0.746	1.00
148_M	240_Y	0.745	1.00
159_P	176_V	0.743	1.00
129_V	229_A	0.742	1.00
272_K	324_L	0.742	1.00
91_L	94_N	0.741	1.00
407_P	410_L	0.739	1.00
73_Q	77_P	0.734	1.00
258_L	261_W	0.733	1.00
404_K	407_P	0.731	1.00
111_A	187_L	0.731	1.00
490_L	495_V	0.731	1.00
451_T	454_T	0.730	1.00
436_S	457_T	0.729	1.00
225_A	239_F	0.726	1.00
279_L	337_Y	0.724	1.00
76_T	81_K	0.724	1.00
290_P	504_A	0.722	1.00
112_P	232_Y	0.722	1.00
223_P	251_I	0.720	1.00
240_Y	244_I	0.720	1.00
325_A	331_I	0.717	1.00
110_I	177_Y	0.717	1.00
478_A	490_L	0.716	1.00
306_L	321_F	0.716	1.00
142_G	154_V	0.716	1.00
111_A	115_G	0.715	1.00
195_T	198_P	0.715	1.00
393_E	443_K	0.715	1.00
451_T	458_S	0.714	1.00
229_A	235_L	0.713	1.00
71_Q	74_V	0.711	1.00
89_G	93_I	0.711	1.00
406_T	438_N	0.711	1.00
93_I	96_L	0.709	1.00
456_K	459_H	0.706	1.00
395_T	423_D	0.706	1.00
350_L	353_H	0.705	1.00
225_A	242_H	0.703	1.00
146_T	218_Y	0.700	1.00
317_N	320_E	0.700	1.00
146_T	216_T	0.697	1.00
193_A	256_V	0.697	1.00
74_V	78_A	0.696	1.00
501_W	505_K	0.696	1.00
227_I	239_F	0.696	1.00
135_R	244_I	0.696	1.00
71_Q	82_R	0.695	1.00
167_S	202_L	0.694	1.00
132_Y	186_S	0.693	1.00
194_A	197_S	0.692	1.00
73_Q	80_Q	0.691	1.00
423_D	479_E	0.691	1.00
328_E	331_I	0.689	1.00
250_G	253_G	0.688	1.00
459_H	463_E	0.686	1.00
82_R	87_I	0.686	1.00
139_F	155_A	0.685	1.00
424_F	465_I	0.685	1.00
134_Y	224_I	0.685	1.00
257_L	261_W	0.684	1.00
350_L	355_D	0.684	1.00
290_P	507_M	0.684	1.00
367_F	408_I	0.683	1.00
185_F	236_I	0.682	1.00
290_P	299_C	0.680	1.00
132_Y	226_A	0.679	1.00
138_P	327_K	0.678	1.00
201_H	204_D	0.677	1.00
99_A	106_C	0.675	1.00
137_T	221_K	0.674	1.00
150_R	218_Y	0.672	1.00
95_E	98_Y	0.670	1.00
238_H	257_L	0.668	1.00
294_I	491_R	0.667	1.00
108_S	112_P	0.664	1.00
180_V	183_T	0.664	1.00
466_I	490_L	0.664	1.00
150_R	213_L	0.663	1.00
181_T	244_I	0.662	1.00
287_Y	309_P	0.658	1.00
133_Y	179_T	0.657	1.00
319_A	323_P	0.657	1.00
183_T	240_Y	0.656	1.00
85_N	89_G	0.656	1.00
275_L	330_M	0.655	1.00
158_N	162_W	0.654	1.00
98_Y	106_C	0.653	1.00
374_A	377_N	0.653	1.00
198_P	202_L	0.653	1.00
449_V	478_A	0.651	1.00
449_V	462_A	0.651	1.00
346_L	389_Q	0.648	1.00
70_Y	73_Q	0.647	1.00
331_I	365_S	0.647	1.00
402_V	406_T	0.645	1.00
459_H	493_R	0.644	1.00
390_I	417_Y	0.641	1.00
270_S	313_G	0.640	1.00
458_S	486_Q	0.640	1.00
158_N	211_G	0.639	1.00
167_S	199_L	0.638	1.00
512_F	515_W	0.636	1.00
186_S	203_K	0.635	1.00
260_L	263_R	0.631	1.00
367_F	398_A	0.629	1.00
182_K	247_L	0.628	1.00
302_A	358_V	0.628	1.00
140_F	244_I	0.625	1.00
418_E	441_I	0.625	1.00
275_L	278_A	0.624	1.00
223_P	246_A	0.624	1.00
127_P	189_K	0.624	1.00
380_T	385_V	0.624	1.00
109_L	112_P	0.623	1.00
476_T	496_R	0.623	1.00
373_I	415_A	0.623	1.00
348_D	513_M	0.622	1.00
129_V	235_L	0.621	1.00
292_I	297_E	0.620	1.00
219_S	276_Q	0.620	1.00
112_P	236_I	0.620	1.00
444_I	495_V	0.619	1.00
336_D	378_Q	0.617	1.00
210_N	217_V	0.616	1.00
139_F	151_G	0.615	1.00
507_M	512_F	0.614	1.00
349_Y	512_F	0.614	1.00
309_P	314_Q	0.614	1.00
340_D	375_R	0.614	1.00
411_A	415_A	0.612	1.00
163_S	176_V	0.611	1.00
274_K	308_W	0.609	1.00
402_V	405_M	0.607	1.00
263_R	267_N	0.606	1.00
160_L	164_E	0.606	1.00
204_D	252_L	0.605	1.00
188_S	196_F	0.604	1.00
490_L	498_C	0.604	1.00
102_N	152_N	0.603	1.00
297_E	484_E	0.602	1.00
482_E	501_W	0.602	1.00
380_T	383_Y	0.600	1.00
334_I	338_V	0.595	1.00
274_K	277_R	0.594	1.00
161_F	210_N	0.594	1.00
376_I	417_Y	0.594	1.00
257_L	262_L	0.592	1.00
336_D	366_D	0.590	1.00
275_L	334_I	0.590	1.00
271_P	274_K	0.590	1.00
266_Q	270_S	0.589	1.00
170_P	199_L	0.588	1.00
146_T	150_R	0.587	1.00
426_I	447_S	0.585	1.00
451_T	455_H	0.584	1.00
260_L	264_I	0.582	1.00
456_K	460_L	0.581	1.00
325_A	329_G	0.581	1.00
392_F	419_V	0.581	1.00
364_A	398_A	0.581	1.00
512_F	516_M	0.579	1.00
270_S	312_Q	0.576	1.00
135_R	143_Y	0.576	1.00
204_D	222_R	0.574	1.00
72_G	78_A	0.573	1.00
230_T	238_H	0.573	1.00
332_E	336_D	0.573	1.00
426_I	448_F	0.573	1.00
139_F	143_Y	0.573	1.00
376_I	379_K	0.571	1.00
264_I	268_Y	0.570	1.00
465_I	469_A	0.570	1.00
127_P	190_E	0.569	1.00
421_I	433_N	0.569	1.00
442_L	474_L	0.568	1.00
285_C	510_Q	0.567	1.00
358_V	385_V	0.567	1.00
316_M	323_P	0.566	1.00
165_V	203_K	0.564	1.00
118_I	121_A	0.563	1.00
350_L	354_A	0.563	1.00
419_V	440_D	0.563	1.00
336_D	369_T	0.560	1.00
165_V	199_L	0.559	1.00
71_Q	79_H	0.556	1.00
84_L	88_R	0.555	1.00
204_D	208_Q	0.554	1.00
460_L	464_H	0.554	1.00
284_L	308_W	0.553	1.00
196_F	226_A	0.553	1.00
432_H	447_S	0.552	1.00
435_K	455_H	0.549	1.00
287_Y	506_A	0.548	1.00
285_C	341_N	0.548	1.00
279_L	334_I	0.548	1.00
120_P	123_Y	0.547	1.00
346_L	390_I	0.547	1.00
263_R	266_Q	0.546	1.00
73_Q	78_A	0.543	1.00
144_K	244_I	0.542	1.00
105_L	176_V	0.542	1.00
513_M	516_M	0.539	1.00
71_Q	78_A	0.539	1.00
78_A	83_M	0.539	1.00
149_Q	214_Y	0.538	1.00
149_Q	153_Y	0.538	1.00
339_I	343_F	0.538	1.00
400_L	405_M	0.537	1.00
269_L	273_R	0.536	1.00
137_T	252_L	0.536	1.00
347_G	385_V	0.534	1.00
485_E	488_N	0.534	1.00
361_N	422_D	0.534	1.00
77_P	81_K	0.533	1.00
161_F	206_T	0.532	1.00
365_S	368_H	0.529	1.00
444_I	465_I	0.529	1.00
114_N	187_L	0.529	1.00
211_G	220_T	0.529	1.00
388_Q	418_E	0.528	1.00
282_H	344_R	0.528	1.00
433_N	436_S	0.528	1.00
329_G	365_S	0.527	1.00
267_N	271_P	0.525	1.00
106_C	177_Y	0.523	1.00
80_Q	84_L	0.523	1.00
385_V	389_Q	0.523	1.00
201_H	254_S	0.522	1.00
149_Q	237_T	0.522	1.00
409_I	438_N	0.522	1.00
378_Q	381_E	0.521	1.00
462_A	478_A	0.520	1.00
335_T	338_V	0.519	1.00
305_L	361_N	0.518	1.00
90_Y	93_I	0.517	1.00
396_E	425_G	0.515	1.00
119_A	229_A	0.514	1.00
412_F	417_Y	0.514	1.00
297_E	503_F	0.514	1.00
118_I	187_L	0.513	1.00
402_V	436_S	0.513	1.00
342_V	346_L	0.511	1.00
339_I	362_L	0.510	1.00
433_N	437_L	0.508	1.00
213_L	216_T	0.508	1.00
461_I	465_I	0.508	1.00
435_K	457_T	0.507	1.00
286_L	341_N	0.507	1.00
372_L	375_R	0.505	0.99
205_L	209_R	0.505	0.99
76_T	83_M	0.504	0.99
265_R	269_L	0.504	0.99
303_E	443_K	0.504	0.99
301_G	359_S	0.501	0.99
410_L	413_R	0.500	0.99
159_P	163_S	0.500	0.99
309_P	313_G	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4rnhA	2	0.7803	100	0.198	Contact Map
4j40A	2	0.4735	100	0.21	Contact Map
3pjxA	1	0.786	100	0.224	Contact Map
3gfzA	2	0.7159	100	0.35	Contact Map
4hjfA	1	0.4905	100	0.392	Contact Map
4hu4A	1	0.464	100	0.459	Contact Map
2r6oA	2	0.483	100	0.464	Contact Map
4kieA	1	0.4905	100	0.465	Contact Map
4rniA	2	0.4773	100	0.468	Contact Map
3sy8A	6	0.7348	100	0.483	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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