GREMLIN Database
YJBH - Uncharacterized lipoprotein YjbH
UniProt: P32689 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11926
Length: 698 (666)
Sequences: 323 (235)
Seq/√Len: 9.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
534_G572_F15.9521.00
42_T153_T9.2591.00
603_Y611_T7.1121.00
602_Q608_K6.0741.00
45_A142_V5.1241.00
76_L111_L4.6120.99
363_I381_V4.5590.99
559_K572_F4.0560.98
615_A648_Y3.9380.98
488_L633_V3.8610.98
613_E648_Y3.5780.96
125_V141_L3.5260.96
329_L356_L3.5100.96
220_L243_V3.4500.96
627_Y670_T3.3970.95
468_A503_V3.2860.94
460_L512_Y3.2820.94
238_K263_N3.0450.91
444_Y471_A2.9520.90
56_N67_S2.8730.89
617_R623_V2.8470.88
596_V612_L2.8440.88
611_T629_T2.8430.88
650_S664_R2.8430.88
583_T599_S2.8430.88
50_E74_P2.7980.87
528_Y571_K2.6700.85
329_L352_V2.6160.83
100_Q103_K2.5560.82
598_A612_L2.5470.82
551_F584_A2.5440.82
147_W152_F2.5410.81
630_I635_K2.4940.80
352_V363_I2.4690.80
156_L203_L2.4650.79
553_L582_L2.4470.79
164_S240_K2.4370.79
106_A280_P2.4060.78
110_K128_R2.4010.77
124_A142_V2.3770.77
169_N178_Y2.3570.76
563_W573_T2.3520.76
520_F540_V2.3140.75
400_A638_Y2.3010.74
584_A600_V2.2960.74
551_F582_L2.2880.74
620_S678_Q2.2750.73
46_R151_D2.2620.73
50_E616_K2.2120.71
557_Y578_K2.2090.71
257_L267_F2.1880.70
529_L680_L2.1870.70
114_W123_V2.1870.70
70_V624_V2.1730.70
627_Y668_G2.1300.68
131_G188_A2.1100.67
560_Q579_T2.0970.67
172_C179_C2.0740.66
44_T249_V2.0740.66
28_G533_F2.0620.66
39_L206_G2.0580.65
170_P178_Y2.0580.65
560_Q671_P2.0290.64
456_L510_A2.0210.64
517_G520_F2.0200.64
45_A124_A1.9860.62
599_S613_E1.9770.62
30_S219_K1.9660.62
598_A610_G1.9650.62
433_Q442_Y1.9530.61
218_L245_A1.9480.61
522_G540_V1.9110.59
339_R654_D1.9090.59
639_G676_G1.9070.59
182_D198_H1.9050.59
596_V614_I1.9040.59
603_Y629_T1.8980.59
47_M112_R1.8940.59
245_A635_K1.8000.55
184_S600_V1.7820.54
47_M75_W1.7690.53
437_G599_S1.7590.53
63_Y261_R1.7530.53
562_D571_K1.7490.52
42_T224_G1.7370.52
125_V188_A1.7110.51
373_P515_H1.7110.51
103_K441_F1.7010.50
209_Y258_S1.6950.50
171_L174_A1.6920.50
31_Q36_G1.6740.49
317_L348_A1.6650.49
618_F674_R1.6590.48
156_L201_A1.6560.48
423_F452_A1.6510.48
270_T435_V1.6400.48
514_Q522_G1.6380.48
246_I254_D1.6320.47
534_G559_K1.6310.47
379_T526_G1.6270.47
153_T259_Y1.6170.47
77_E151_D1.5980.46
42_T142_V1.5970.46
219_K493_T1.5860.45
329_L465_S1.5840.45
141_L302_S1.5820.45
208_E217_R1.5820.45
537_G542_Y1.5810.45
35_G39_L1.5430.43
37_V48_A1.5410.43
325_K534_G1.5370.43
232_A235_L1.5370.43
269_V427_I1.5310.43
388_L392_P1.5290.43
119_W274_N1.5280.43
164_S237_Q1.5280.43
114_W207_V1.5260.43
583_T679_Q1.5240.43
346_I629_T1.5220.43
533_F687_Y1.5030.42
509_Q683_K1.4910.41
563_W571_K1.4910.41
113_L493_T1.4890.41
122_Q144_S1.4890.41
207_V533_F1.4820.41
167_V497_E1.4800.41
167_V171_L1.4750.41
270_T459_H1.4720.40
640_E676_G1.4650.40
49_R201_A1.4640.40
436_G441_F1.4630.40
522_G526_G1.4580.40
29_P124_A1.4570.40
356_L363_I1.4500.39
82_Y227_Y1.4440.39
328_T364_R1.4370.39
144_S153_T1.4340.39
630_I634_S1.4230.38
217_R254_D1.4120.38
490_R496_R1.4070.38
138_A202_S1.3890.37
77_E110_K1.3880.37
39_L205_G1.3830.37
330_Y366_T1.3800.37
429_P508_L1.3780.37
160_Y443_M1.3750.36
86_R101_T1.3740.36
133_T640_E1.3730.36
188_A642_D1.3730.36
467_F661_T1.3720.36
225_N441_F1.3700.36
170_P201_A1.3700.36
575_Y579_T1.3670.36
140_Y204_F1.3640.36
144_S191_I1.3640.36
154_L203_L1.3560.36
559_K576_S1.3560.36
44_T373_P1.3470.35
40_L661_T1.3460.35
509_Q525_Y1.3450.35
511_N690_T1.3420.35
455_W461_L1.3410.35
109_L276_N1.3340.35
538_A555_A1.3320.35
153_T506_N1.3320.35
151_D261_R1.3280.35
65_Y230_D1.3280.35
157_G547_S1.3220.34
40_L258_S1.3200.34
153_T192_D1.3100.34
505_V576_S1.3000.33
577_V602_Q1.2840.33
623_V678_Q1.2820.33
74_P624_V1.2790.33
331_V540_V1.2760.32
389_A392_P1.2710.32
589_S636_E1.2680.32
257_L628_A1.2630.32
438_P489_P1.2610.32
194_S238_K1.2600.32
167_V201_A1.2600.32
225_N436_G1.2460.31
490_R664_R1.2430.31
557_Y576_S1.2420.31
110_K151_D1.2420.31
326_G363_I1.2410.31
70_V330_Y1.2400.31
59_D86_R1.2350.31
163_T228_Q1.2300.31
255_V555_A1.2290.31
112_R274_N1.2270.31
456_L462_T1.2250.31
35_G38_G1.2230.30
317_L633_V1.2190.30
327_D361_K1.2170.30
84_D100_Q1.1970.30
167_V372_M1.1960.29
581_H611_T1.1940.29
581_H629_T1.1920.29
640_E674_R1.1880.29
578_K602_Q1.1840.29
41_Q136_F1.1830.29
583_T597_K1.1820.29
202_S606_G1.1820.29
141_L500_Q1.1760.29
525_Y682_R1.1740.29
193_G196_M1.1740.29
477_F493_T1.1740.29
138_A161_L1.1720.29
533_F680_L1.1720.29
54_S69_S1.1600.28
364_R376_T1.1600.28
57_Y64_R1.1590.28
643_F676_G1.1570.28
243_V470_L1.1570.28
84_D103_K1.1560.28
124_A555_A1.1550.28
404_V471_A1.1510.28
32_S44_T1.1500.28
503_V612_L1.1500.28
138_A533_F1.1490.28
368_N373_P1.1460.28
639_G643_F1.1440.28
143_A429_P1.1420.28
420_K653_L1.1410.28
437_G479_Y1.1380.27
381_V385_K1.1360.27
144_S586_W1.1340.27
194_S289_Q1.1320.27
45_A140_Y1.1260.27
516_L522_G1.1260.27
56_N540_V1.1230.27
291_Q612_L1.1210.27
525_Y537_G1.1180.27
219_K246_I1.1170.27
99_D156_L1.1160.27
505_V570_M1.1120.27
605_A643_F1.1100.26
259_Y265_F1.1080.26
225_N261_R1.1070.26
106_A630_I1.1070.26
261_R441_F1.1050.26
87_T233_G1.1050.26
645_K676_G1.1030.26
287_R346_I1.0990.26
31_Q48_A1.0960.26
179_C678_Q1.0910.26
293_Q385_K1.0880.26
328_T508_L1.0860.26
637_E649_V1.0810.25
76_L127_A1.0800.25
600_V610_G1.0750.25
169_N174_A1.0750.25
374_Q493_T1.0740.25
431_L439_E1.0740.25
287_R343_E1.0730.25
32_S128_R1.0700.25
625_G676_G1.0690.25
460_L586_W1.0690.25
71_Q161_L1.0670.25
344_G505_V1.0650.25
597_K615_A1.0650.25
131_G192_D1.0620.25
338_Y521_Y1.0590.25
445_Q472_N1.0590.25
161_L550_A1.0590.25
88_R232_A1.0590.25
639_G645_K1.0580.25
47_M113_L1.0570.25
60_N237_Q1.0570.25
427_I692_D1.0570.25
372_M420_K1.0560.25
82_Y640_E1.0560.25
125_V162_G1.0530.25
84_D488_L1.0520.25
45_A558_V1.0520.25
577_V606_G1.0520.25
139_E541_L1.0480.24
533_F611_T1.0470.24
622_V684_F1.0460.24
104_D133_T1.0440.24
585_Y677_G1.0430.24
518_N598_A1.0390.24
505_V571_K1.0380.24
580_G640_E1.0370.24
625_G639_G1.0360.24
205_G666_A1.0360.24
46_R110_K1.0330.24
231_F690_T1.0330.24
142_V153_T1.0320.24
575_Y633_V1.0310.24
564_R569_M1.0290.24
331_V363_I1.0270.24
460_L510_A1.0260.24
41_Q436_G1.0260.24
150_F309_T1.0230.24
122_Q140_Y1.0230.24
111_L125_V1.0180.23
638_Y670_T1.0180.23
150_F292_P1.0180.23
351_I360_I1.0160.23
133_T674_R1.0150.23
451_T465_S1.0120.23
149_P258_S1.0120.23
63_Y441_F1.0110.23
63_Y225_N1.0090.23
53_L273_T1.0030.23
364_R378_E1.0020.23
257_L409_P0.9990.23
284_D555_A0.9980.23
638_Y644_T0.9970.23
84_D101_T0.9970.23
434_S660_P0.9960.23
131_G160_Y0.9950.23
290_Y324_A0.9940.23
559_K578_K0.9910.23
486_S616_K0.9890.23
119_W248_R0.9880.23
310_L626_G0.9860.22
346_I384_L0.9820.22
165_G169_N0.9800.22
127_A435_V0.9800.22
390_G534_G0.9780.22
537_G682_R0.9750.22
496_R525_Y0.9720.22
26_P649_V0.9720.22
169_N201_A0.9720.22
56_N138_A0.9670.22
150_F692_D0.9670.22
524_V538_A0.9650.22
509_Q682_R0.9640.22
102_Y508_L0.9630.22
58_R517_G0.9630.22
230_D644_T0.9620.22
321_Q516_L0.9600.22
350_R384_L0.9590.22
69_S79_T0.9570.22
137_D196_M0.9560.22
170_P605_A0.9560.22
59_D64_R0.9540.22
640_E643_F0.9540.22
63_Y136_F0.9530.21
162_G671_P0.9470.21
146_A210_Q0.9460.21
170_P438_P0.9460.21
28_G144_S0.9440.21
642_D676_G0.9440.21
168_K176_D0.9440.21
135_L493_T0.9440.21
21_E24_P0.9420.21
387_H691_S0.9410.21
48_A69_S0.9400.21
511_N684_F0.9380.21
515_H602_Q0.9330.21
269_V348_A0.9290.21
329_L360_I0.9280.21
208_E442_Y0.9260.21
519_G533_F0.9250.21
267_F534_G0.9240.21
469_N472_N0.9210.21
102_Y231_F0.9200.21
114_W689_M0.9190.20
243_V326_G0.9170.20
256_N666_A0.9170.20
466_L515_H0.9170.20
612_L632_N0.9170.20
164_S427_I0.9160.20
441_F496_R0.9140.20
136_F433_Q0.9140.20
75_W693_R0.9130.20
230_D573_T0.9110.20
75_W112_R0.9100.20
174_A466_L0.9080.20
207_V299_L0.9080.20
633_V640_E0.9060.20
351_I471_A0.9060.20
429_P597_K0.9040.20
524_V593_D0.9030.20
141_L255_V0.9030.20
167_V401_Q0.9030.20
476_K543_R0.9010.20
194_S659_G0.8990.20
438_P624_V0.8970.20
556_N682_R0.8940.20
106_A282_Y0.8930.20
49_R364_R0.8930.20
477_F496_R0.8920.20
611_T687_Y0.8910.20
311_L680_L0.8910.20
374_Q533_F0.8880.20
601_G607_D0.8880.20
601_G652_P0.8880.20
607_D652_P0.8880.20
555_A558_V0.8860.20
172_C644_T0.8850.20
137_D683_K0.8840.20
257_L265_F0.8830.19
56_N692_D0.8830.19
212_P216_L0.8820.19
338_Y344_G0.8790.19
85_V102_Y0.8770.19
42_T484_Q0.8760.19
49_R551_F0.8760.19
444_Y490_R0.8740.19
47_M444_Y0.8740.19
225_N433_Q0.8720.19
105_K261_R0.8680.19
124_A254_D0.8670.19
210_Q311_L0.8670.19
460_L564_R0.8660.19
416_W533_F0.8660.19
109_L127_A0.8660.19
54_S218_L0.8630.19
106_A626_G0.8620.19
110_K212_P0.8610.19
337_K356_L0.8580.19
455_W501_N0.8560.19
189_G639_G0.8550.19
474_Y496_R0.8530.19
366_T422_R0.8520.19
80_L629_T0.8510.19
132_G674_R0.8500.19
247_Y521_Y0.8500.19
331_V672_L0.8490.19
111_L114_W0.8490.19
565_S571_K0.8480.19
366_T376_T0.8470.19
558_V656_F0.8440.18
144_S288_P0.8440.18
209_Y220_L0.8420.18
29_P45_A0.8410.18
587_T593_D0.8380.18
247_Y434_S0.8380.18
106_A308_L0.8380.18
662_R692_D0.8370.18
83_T102_Y0.8370.18
136_F493_T0.8370.18
171_L577_V0.8370.18
585_Y625_G0.8370.18
185_Y188_A0.8370.18
175_S194_S0.8360.18
348_A509_Q0.8340.18
169_N172_C0.8330.18
187_Q659_G0.8320.18
322_I331_V0.8320.18
506_N534_G0.8320.18
657_S661_T0.8320.18
61_D562_D0.8310.18
438_P671_P0.8300.18
54_S124_A0.8270.18
452_A612_L0.8240.18
189_G640_E0.8230.18
42_T223_E0.8230.18
149_P434_S0.8220.18
612_L630_I0.8220.18
628_A633_V0.8200.18
44_T365_I0.8170.18
189_G676_G0.8160.18
64_R86_R0.8160.18
525_Y669_W0.8150.18
130_I627_Y0.8120.18
45_A155_G0.8100.18
109_L366_T0.8100.18
588_P678_Q0.8090.18
431_L442_Y0.8060.17
148_G649_V0.8060.17
266_M599_S0.8030.17
157_G684_F0.8020.17
49_R305_A0.8010.17
139_E643_F0.7990.17
432_N617_R0.7980.17
612_L628_A0.7980.17
56_N239_S0.7970.17
48_A315_A0.7950.17
112_R433_Q0.7940.17
202_S447_G0.7930.17
358_D534_G0.7920.17
178_Y636_E0.7920.17
163_T167_V0.7910.17
161_L505_V0.7910.17
34_F663_S0.7900.17
447_G657_S0.7900.17
524_V540_V0.7880.17
45_A463_T0.7880.17
49_R255_V0.7870.17
353_M381_V0.7860.17
134_G139_E0.7850.17
329_L409_P0.7840.17
225_N669_W0.7830.17
82_Y189_G0.7830.17
327_D356_L0.7820.17
639_G642_D0.7820.17
63_Y525_Y0.7820.17
610_G630_I0.7790.17
86_R100_Q0.7780.17
477_F669_W0.7780.17
627_Y692_D0.7780.17
139_E158_W0.7780.17
46_R77_E0.7740.17
62_Q660_P0.7730.17
138_A195_Q0.7720.17
489_P628_A0.7710.17
110_K469_N0.7700.17
504_Y565_S0.7700.17
62_Q644_T0.7700.17
470_L512_Y0.7690.17
342_R346_I0.7690.17
47_M115_E0.7680.17
116_E121_P0.7680.17
119_W362_T0.7680.17
373_P387_H0.7680.17
599_S679_Q0.7670.16
601_G646_G0.7660.16
607_D646_G0.7660.16
646_G652_P0.7660.16
160_Y437_G0.7660.16
223_E436_G0.7660.16
325_K627_Y0.7650.16
274_N476_K0.7650.16
338_Y647_V0.7640.16
112_R162_G0.7630.16
581_H603_Y0.7630.16
316_G338_Y0.7630.16
142_V533_F0.7630.16
74_P356_L0.7620.16
313_Y505_V0.7620.16
533_F603_Y0.7610.16
363_I665_A0.7600.16
29_P74_P0.7600.16
80_L644_T0.7580.16
130_I254_D0.7580.16
117_S120_L0.7570.16
102_Y156_L0.7560.16
239_S264_T0.7560.16
98_G205_G0.7550.16
529_L534_G0.7550.16
153_T208_E0.7540.16
44_T673_T0.7530.16
180_Y636_E0.7520.16
640_E672_L0.7520.16
109_L635_K0.7510.16
123_V452_A0.7510.16
245_A584_A0.7510.16
430_V447_G0.7500.16
162_G342_R0.7490.16
139_E199_G0.7490.16
490_R534_G0.7490.16
365_I656_F0.7470.16
641_G674_R0.7470.16
65_Y575_Y0.7470.16
485_D624_V0.7460.16
87_T565_S0.7430.16
202_S544_P0.7430.16
263_N526_G0.7420.16
174_A177_K0.7410.16
202_S208_E0.7400.16
374_Q608_K0.7370.16
557_Y602_Q0.7360.16
26_P171_L0.7350.16
156_L214_Q0.7330.16
209_Y546_D0.7330.16
84_D87_T0.7320.16
537_G648_Y0.7320.16
127_A130_I0.7300.16
477_F525_Y0.7300.16
170_P489_P0.7290.16
529_L540_V0.7290.16
597_K613_E0.7260.16
203_L598_A0.7250.16
575_Y605_A0.7240.15
62_Q234_K0.7230.15
326_G329_L0.7230.15
196_M461_L0.7230.15
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77_E212_P0.5810.12
261_R433_Q0.5810.12
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543_R690_T0.5740.12
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259_Y367_E0.5700.12
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202_S222_Y0.5690.12
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160_Y230_D0.5610.12
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31_Q69_S0.5550.12
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325_K328_T0.5540.12
526_G563_W0.5530.12
496_R664_R0.5530.12
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300_Q408_V0.5510.12
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62_Q100_Q0.5320.12
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586_W617_R0.5260.11
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337_K650_S0.5260.11
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399_L402_K0.5250.11
444_Y496_R0.5250.11
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484_Q487_H0.5240.11
169_N533_F0.5220.11
349_N379_T0.5210.11
447_G661_T0.5210.11
265_F633_V0.5210.11
280_P308_L0.5200.11
548_N596_V0.5200.11
224_G437_G0.5200.11
345_I464_G0.5200.11
451_T688_D0.5190.11
265_F606_G0.5190.11
214_Q582_L0.5190.11
484_Q494_H0.5180.11
512_Y657_S0.5180.11
52_E274_N0.5180.11
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533_F574_D0.5160.11
307_Q536_A0.5150.11
110_K690_T0.5140.11
644_T670_T0.5140.11
275_F528_Y0.5130.11
470_L593_D0.5130.11
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414_Q422_R0.5120.11
217_R466_L0.5110.11
543_R554_D0.5110.11
591_A596_V0.5110.11
165_G611_T0.5100.11
222_Y429_P0.5100.11
114_W524_V0.5100.11
63_Y151_D0.5100.11
263_N488_L0.5100.11
114_W636_E0.5090.11
618_F642_D0.5090.11
104_D640_E0.5090.11
85_V88_R0.5090.11
58_R67_S0.5090.11
581_H631_T0.5090.11
507_N683_K0.5090.11
251_D366_T0.5080.11
550_A687_Y0.5070.11
620_S655_L0.5070.11
59_D144_S0.5060.11
278_L570_M0.5060.11
67_S528_Y0.5050.11
335_Q469_N0.5050.11
318_A555_A0.5050.11
540_V692_D0.5050.11
105_K558_V0.5040.11
196_M429_P0.5030.11
170_P200_P0.5030.11
443_M472_N0.5030.11
209_Y322_I0.5030.11
350_R534_G0.5030.11
153_T578_K0.5020.11
20_G24_P0.5020.11
451_T466_L0.5020.11
141_L193_G0.5020.11
105_K225_N0.5010.11
281_S678_Q0.5010.11
55_L207_V0.5010.11
165_G603_Y0.5000.11
57_Y176_D0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3nb3A 2 0.1963 96.7 0.972 Contact Map
2k0lA 1 0.2951 90.5 0.98 Contact Map
3qraA 1 0.1948 89.7 0.98 Contact Map
1ormA 1 0.1877 76.7 0.983 Contact Map
4pwuA 4 0.1017 51.7 0.986 Contact Map
1qjpA 1 0.1848 51 0.986 Contact Map
1uv7A 2 0.1089 47.3 0.986 Contact Map
2x55A 1 0.2908 31.7 0.987 Contact Map
4rlcA 1 0.1676 24.9 0.988 Contact Map
2lhfA 1 0.2235 19.3 0.988 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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