GREMLIN Database
YJBG - Uncharacterized protein YjbG
UniProt: P32688 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11925
Length: 245 (216)
Sequences: 858 (703)
Seq/√Len: 47.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
41_E49_Q4.0751.00
56_W59_G3.2091.00
189_Y210_M2.7571.00
189_Y213_S2.7371.00
44_I129_N2.7271.00
58_P210_M2.6891.00
60_A117_L2.5611.00
185_A217_V2.5201.00
188_V216_Y2.4551.00
228_P232_N2.4071.00
227_T230_A2.3311.00
165_R169_S2.3221.00
27_F137_T2.2791.00
74_Q77_A2.2551.00
171_L176_L2.2221.00
187_V205_R2.1811.00
228_P231_L2.1331.00
24_V46_L2.0841.00
69_A73_R2.0231.00
77_A81_R2.0060.99
65_E68_T1.9460.99
147_V209_P1.9190.99
226_E230_A1.9170.99
28_S33_E1.8360.99
108_K111_G1.8270.99
60_A138_L1.8030.99
162_T169_S1.7940.99
90_S93_D1.7780.99
148_T158_K1.7690.99
190_P213_S1.7440.98
225_S228_P1.7430.98
225_S231_L1.7350.98
37_L41_E1.7230.98
72_L109_V1.7190.98
152_L177_L1.6940.98
72_L108_K1.6880.98
47_V138_L1.6590.98
73_R77_A1.6200.98
165_R173_D1.5790.97
83_A103_Q1.5420.97
50_P218_G1.5060.96
33_E51_R1.5030.96
104_I111_G1.5020.96
75_Q78_L1.4990.96
167_V197_A1.4870.96
109_V112_R1.4720.96
149_L153_I1.4710.96
26_V53_A1.4660.96
42_H45_D1.4580.95
209_P213_S1.4370.95
116_N119_P1.4340.95
35_K51_R1.4240.95
224_W230_A1.4170.95
72_L76_Q1.4070.94
20_A39_G1.4050.94
105_Q111_G1.3980.94
104_I109_V1.3940.94
227_T232_N1.3930.94
167_V209_P1.3540.93
187_V212_G1.3480.93
229_D233_A1.3480.93
64_E136_Y1.3440.93
83_A105_Q1.3400.93
170_Y192_G1.3330.93
176_L180_A1.3200.92
159_Q174_Q1.3070.92
46_L132_L1.3020.92
226_E232_N1.2920.91
33_E52_L1.2810.91
228_P233_A1.2700.91
74_Q85_Q1.2700.91
55_S64_E1.2650.91
229_D232_N1.2620.90
28_S141_G1.2510.90
187_V215_I1.2400.90
125_A129_N1.2380.90
76_Q80_T1.2330.89
158_K169_S1.2280.89
61_V139_W1.2260.89
136_Y175_S1.2230.89
227_T233_A1.2230.89
198_P205_R1.2150.89
152_L219_L1.2150.89
78_L81_R1.2020.88
136_Y141_G1.1950.88
115_I138_L1.1940.88
224_W229_D1.1910.88
71_A75_Q1.1760.87
46_L138_L1.1620.86
188_V192_G1.1580.86
70_A73_R1.1550.86
72_L75_Q1.1530.86
28_S64_E1.1390.85
171_L185_A1.1240.84
199_V202_W1.0990.83
74_Q78_L1.0890.82
130_P162_T1.0860.82
75_Q82_L1.0840.82
46_L119_P1.0820.82
38_T139_W1.0800.82
28_S55_S1.0770.82
216_Y220_A1.0670.81
148_T214_I1.0590.81
225_S230_A1.0570.81
64_E141_G1.0570.81
105_Q109_V1.0550.80
37_L49_Q1.0480.80
187_V195_Q1.0450.80
46_L50_P1.0350.79
89_S95_A1.0340.79
25_K137_T1.0250.78
33_E218_G1.0060.77
67_A71_A1.0030.77
206_H209_P1.0020.77
26_V47_V1.0000.77
225_S233_A0.9970.76
64_E135_N0.9940.76
153_I217_V0.9900.76
71_A74_Q0.9870.76
42_H129_N0.9820.75
221_D225_S0.9780.75
51_R55_S0.9700.74
168_A200_A0.9640.74
60_A115_I0.9630.74
33_E53_A0.9490.73
146_T212_G0.9480.73
55_S141_G0.9470.73
92_D95_A0.9420.72
79_L104_I0.9400.72
28_S136_Y0.9380.72
93_D96_A0.9360.72
118_D202_W0.9350.72
161_F215_I0.9320.71
99_A102_Q0.9200.70
20_A25_K0.9200.70
210_M213_S0.9160.70
45_D49_Q0.9130.70
192_G212_G0.9100.70
75_Q81_R0.9100.70
107_L111_G0.9080.69
81_R84_E0.9080.69
224_W232_N0.9050.69
226_E233_A0.8950.68
33_E55_S0.8900.68
140_V175_S0.8820.67
225_S232_N0.8790.67
68_T74_Q0.8770.67
107_L110_T0.8740.67
77_A86_G0.8730.66
50_P60_A0.8680.66
49_Q52_L0.8630.66
186_W218_G0.8630.66
171_L209_P0.8610.65
176_L185_A0.8610.65
145_S160_P0.8610.65
163_P168_A0.8600.65
209_P215_I0.8600.65
28_S35_K0.8430.64
27_F139_W0.8410.64
227_T231_L0.8410.64
149_L166_D0.8380.63
100_L104_I0.8340.63
28_S32_S0.8280.62
89_S92_D0.8230.62
135_N153_I0.8150.61
190_P194_T0.8150.61
89_S93_D0.8040.60
140_V196_K0.8040.60
124_V214_I0.8020.60
187_V209_P0.8010.60
70_A74_Q0.7890.59
136_Y174_Q0.7870.58
99_A105_Q0.7860.58
89_S94_A0.7860.58
31_S216_Y0.7850.58
173_D209_P0.7750.57
27_F102_Q0.7730.57
89_S215_I0.7700.57
162_T165_R0.7660.56
102_Q105_Q0.7630.56
16_S104_I0.7620.56
123_R135_N0.7600.56
162_T173_D0.7590.56
104_I140_V0.7580.56
185_A189_Y0.7550.55
79_L82_L0.7520.55
81_R85_Q0.7520.55
29_N33_E0.7500.55
130_P166_D0.7500.55
35_K52_L0.7460.54
73_R84_E0.7450.54
224_W227_T0.7420.54
76_Q106_A0.7400.54
91_A140_V0.7370.53
24_V132_L0.7360.53
199_V203_N0.7300.53
42_H229_D0.7260.52
72_L103_Q0.7230.52
102_Q106_A0.7170.51
29_N40_A0.7170.51
29_N53_A0.7140.51
93_D97_I0.7120.51
93_D99_A0.7060.50
55_S136_Y0.7050.50
21_A27_F0.7030.50
91_A96_A0.6990.50
115_I125_A0.6990.50
168_A206_H0.6970.49
59_G141_G0.6960.49
52_L64_E0.6950.49
224_W231_L0.6920.49
152_L179_G0.6900.49
31_S35_K0.6890.49
60_A218_G0.6870.48
90_S94_A0.6860.48
189_Y209_P0.6850.48
18_V21_A0.6840.48
65_E69_A0.6840.48
89_S96_A0.6820.48
167_V185_A0.6800.48
164_G208_E0.6790.48
62_I220_A0.6730.47
35_K46_L0.6730.47
64_E71_A0.6680.47
187_V230_A0.6670.46
226_E231_L0.6620.46
51_R62_I0.6610.46
75_Q227_T0.6600.46
32_S41_E0.6570.45
71_A111_G0.6560.45
75_Q80_T0.6520.45
29_N55_S0.6490.45
28_S153_I0.6490.45
136_Y218_G0.6480.45
143_P163_P0.6450.44
87_A97_I0.6380.44
94_A103_Q0.6350.43
120_D213_S0.6340.43
181_D184_Y0.6340.43
77_A108_K0.6340.43
95_A161_F0.6330.43
83_A106_A0.6300.43
72_L79_L0.6280.43
104_I107_L0.6270.42
38_T161_F0.6270.42
71_A87_A0.6260.42
73_R94_A0.6260.42
95_A99_A0.6250.42
51_R194_T0.6220.42
153_I175_S0.6220.42
220_A228_P0.6200.42
78_L82_L0.6150.41
133_Q142_P0.6140.41
177_L215_I0.6140.41
111_G114_K0.6090.41
213_S217_V0.6070.41
91_A99_A0.6070.41
121_I124_V0.6010.40
25_K46_L0.6000.40
166_D169_S0.5980.40
88_D149_L0.5980.40
96_A99_A0.5970.40
43_L130_P0.5940.39
98_N178_S0.5930.39
67_A113_Q0.5910.39
50_P55_S0.5880.39
45_D60_A0.5850.38
63_S110_T0.5820.38
87_A216_Y0.5820.38
88_D100_L0.5790.38
26_V172_S0.5780.38
35_K44_I0.5770.38
66_L71_A0.5750.37
170_Y202_W0.5720.37
224_W233_A0.5710.37
162_T172_S0.5700.37
168_A180_A0.5670.37
212_G216_Y0.5670.37
80_T107_L0.5660.37
164_G169_S0.5660.37
226_E229_D0.5630.36
64_E67_A0.5560.36
47_V182_R0.5540.35
23_T161_F0.5540.35
94_A98_N0.5520.35
75_Q85_Q0.5510.35
29_N46_L0.5510.35
128_G142_P0.5500.35
101_R104_I0.5490.35
77_A118_D0.5480.35
170_Y188_V0.5430.34
20_A40_A0.5430.34
73_R149_L0.5380.34
136_Y153_I0.5370.34
33_E50_P0.5360.34
79_L85_Q0.5320.34
28_S149_L0.5310.33
103_Q116_N0.5310.33
124_V185_A0.5310.33
164_G209_P0.5300.33
179_G219_L0.5290.33
72_L102_Q0.5280.33
60_A170_Y0.5270.33
177_L180_A0.5240.33
130_P189_Y0.5240.33
83_A122_V0.5240.33
52_L129_N0.5220.33
98_N102_Q0.5220.33
53_A62_I0.5210.33
63_S137_T0.5200.32
34_A128_G0.5180.32
63_S196_K0.5170.32
72_L147_V0.5140.32
59_G92_D0.5130.32
77_A228_P0.5120.32
63_S139_W0.5120.32
100_L108_K0.5110.32
84_E87_A0.5090.31
42_H159_Q0.5090.31
197_A212_G0.5050.31
95_A126_E0.5040.31
182_R209_P0.5010.31
74_Q140_V0.5010.31
134_G198_P0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3p42A 2 0.9224 100 0.341 Contact Map
2j58A 5 0.7673 99.7 0.717 Contact Map
4uz3A 1 0.4041 43.9 0.943 Contact Map
1e0gA 1 0.1959 29.9 0.948 Contact Map
4b8vA 2 0.7143 29.3 0.948 Contact Map
1ryjA 1 0.2816 23.5 0.95 Contact Map
4hrsA 2 0.2694 23 0.951 Contact Map
2l32A 1 0.2694 21.6 0.951 Contact Map
2q5wD 1 0.2939 21.2 0.951 Contact Map
2f0cA 3 0.551 20.2 0.952 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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