GREMLIN Database
PFLD - Formate acetyltransferase 2
UniProt: P32674 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11910
Length: 765 (687)
Sequences: 1552 (723)
Seq/√Len: 27.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
281_Q285_T5.8431.00
724_E728_R4.7361.00
211_E234_R4.6971.00
415_S425_P4.4781.00
458_Y589_I4.0741.00
584_D667_K3.8871.00
334_T338_R3.8251.00
282_T286_Q3.7071.00
539_G544_Q3.6811.00
532_D653_Q3.5711.00
289_D293_L3.5371.00
559_N637_F3.3491.00
248_C296_L3.2751.00
243_T288_E3.2591.00
235_H242_Q3.2301.00
87_L112_R3.1771.00
751_K755_D3.1501.00
277_L281_Q3.1211.00
353_Q385_G3.0751.00
49_Y53_H2.9971.00
530_L593_L2.9521.00
228_T231_E2.9421.00
470_S600_E2.8961.00
48_A52_E2.8951.00
230_A237_A2.8491.00
353_Q382_I2.8071.00
350_D377_K2.8041.00
170_G238_Q2.7741.00
284_L289_D2.7661.00
173_V197_E2.7321.00
372_T376_M2.7011.00
719_A723_R2.6831.00
582_D663_K2.6320.99
143_Q628_V2.6220.99
22_E55_E2.6040.99
280_Y296_L2.6040.99
247_A279_F2.5670.99
170_G239_H2.5390.99
543_E571_R2.5320.99
248_C297_L2.5060.99
239_H242_Q2.5020.99
209_L212_T2.5010.99
244_F293_L2.4880.99
207_A234_R2.4880.99
631_A637_F2.4640.99
269_L300_L2.4500.99
724_E731_D2.4450.99
272_F348_C2.4250.99
728_R731_D2.4020.99
178_Q182_Q2.4010.99
442_V469_I2.4010.99
726_Q751_K2.4000.99
726_Q755_D2.3470.99
114_E118_Y2.3240.99
475_L479_G2.3080.98
226_L495_L2.2980.98
167_H175_Q2.2980.98
177_Q181_Q2.2720.98
272_F276_M2.2620.98
203_I237_A2.2580.98
280_Y293_L2.2430.98
535_H585_E2.2400.98
77_M86_L2.2390.98
136_V482_I2.2330.98
134_D181_Q2.2020.98
233_S253_Y2.1990.98
139_A475_L2.1960.98
32_R114_E2.1790.98
30_S34_T2.1670.98
595_R672_L2.1450.98
346_F373_P2.1380.97
174_A178_Q2.1360.97
466_R600_E2.1170.97
333_L339_S2.1080.97
376_M695_R2.0940.97
58_I210_A2.0910.97
466_R596_H2.0740.97
174_A177_Q2.0530.97
529_N632_T2.0410.97
245_W292_F2.0380.97
560_F572_L2.0300.96
244_F280_Y2.0250.96
447_L567_K2.0160.96
210_A229_I2.0050.96
237_A253_Y1.9720.96
480_S522_V1.9690.96
531_S590_S1.9670.96
136_V479_G1.9640.96
45_K104_S1.9470.96
29_A33_Q1.9240.95
606_N610_G1.9210.95
65_A229_I1.8950.95
228_T232_I1.8630.94
204_L238_Q1.8370.94
451_E454_A1.8340.94
230_A253_Y1.8290.94
379_A698_A1.8260.94
453_N460_G1.8130.93
49_Y52_E1.7910.93
175_Q179_H1.7770.93
283_S288_E1.7720.93
455_A543_E1.7610.92
663_K707_L1.7560.92
55_E232_I1.7540.92
466_R592_E1.7500.92
301_W348_C1.7480.92
294_K347_L1.7430.92
261_E494_P1.7420.92
451_E460_G1.7390.92
457_T542_F1.7370.92
382_I385_G1.7360.92
235_H239_H1.7350.92
353_Q377_K1.7330.92
232_I246_Q1.7330.92
529_N634_D1.7250.92
517_Y611_Y1.7180.91
19_I63_L1.7100.91
209_L213_M1.7020.91
422_L670_N1.6980.91
662_L712_I1.6980.91
179_H182_Q1.6960.91
176_M193_L1.6910.91
457_T460_G1.6900.91
52_E201_K1.6880.91
208_E234_R1.6770.90
704_F709_L1.6750.90
33_Q37_E1.6740.90
259_Q307_I1.6720.90
63_L299_S1.6680.90
345_S374_F1.6650.90
241_P250_L1.6230.89
26_L53_H1.6030.88
294_K298_E1.6030.88
204_L208_E1.5970.88
91_D102_A1.5780.87
58_I67_N1.5760.87
459_E462_L1.5710.87
293_L296_L1.5670.87
566_E570_A1.5670.87
458_Y538_K1.5660.87
200_Q203_I1.5580.87
248_C300_L1.5570.87
164_L254_M1.5510.86
179_H502_D1.5450.86
30_S40_I1.5430.86
661_V679_L1.5340.86
341_V374_F1.5310.86
207_A211_E1.5310.86
164_L499_F1.5270.86
539_G585_E1.5260.86
575_R578_K1.5230.85
204_L234_R1.5220.85
600_E603_K1.5180.85
26_L49_Y1.5180.85
232_I235_H1.5160.85
273_D345_S1.5150.85
176_M504_L1.5110.85
173_V177_Q1.5030.85
29_A32_R1.5030.85
235_H246_Q1.5020.85
227_L238_Q1.4900.84
203_I236_N1.4850.84
566_E569_R1.4800.84
368_A395_E1.4790.84
223_R227_L1.4770.84
35_E118_Y1.4750.84
269_L272_F1.4700.83
231_E242_Q1.4680.83
26_L29_A1.4650.83
456_L460_G1.4570.83
169_L226_L1.4490.82
171_E174_A1.4450.82
464_Q468_K1.4410.82
588_N592_E1.4300.82
289_D296_L1.4130.81
33_Q49_Y1.4120.81
538_K543_E1.4080.81
442_V468_K1.4080.81
229_I237_A1.4060.80
225_E494_P1.4040.80
10_T377_K1.4000.80
177_Q193_L1.3990.80
200_Q204_L1.3880.80
134_D137_K1.3810.79
529_N643_A1.3770.79
33_Q36_G1.3670.79
209_L502_D1.3640.78
662_L679_L1.3600.78
80_E116_F1.3550.78
443_M461_L1.3520.78
443_M537_L1.3510.78
37_E45_K1.3510.78
637_F640_E1.3500.78
528_A643_A1.3490.78
37_E101_F1.3460.77
208_E212_T1.3450.77
20_S70_V1.3400.77
237_A250_L1.3370.77
243_T293_L1.3360.77
280_Y343_V1.3350.77
199_S257_I1.3250.76
750_S753_I1.3200.76
297_L348_C1.3190.76
569_R637_F1.3180.76
23_R302_V1.3090.75
524_G597_Y1.3000.75
299_S302_V1.2980.75
592_E596_H1.2950.75
136_V475_L1.2930.74
540_M576_F1.2870.74
650_M653_Q1.2800.74
330_L345_S1.2710.73
274_Q340_A1.2630.73
423_S500_I1.2590.72
200_Q238_Q1.2510.72
562_T566_E1.2510.72
34_T45_K1.2490.72
63_L245_W1.2470.72
225_E228_T1.2450.72
134_D138_A1.2420.71
224_E228_T1.2410.71
578_K655_A1.2400.71
173_V193_L1.2400.71
10_T373_P1.2400.71
679_L712_I1.2360.71
203_I250_L1.2350.71
232_I245_W1.2290.71
536_A572_L1.2270.70
63_L296_L1.2250.70
462_L592_E1.2240.70
25_L114_E1.2240.70
679_L709_L1.2120.70
273_D328_A1.2070.69
228_T243_T1.2060.69
283_S289_D1.2020.69
56_I209_L1.1980.69
229_I253_Y1.1920.68
37_E40_I1.1880.68
173_V213_M1.1860.68
382_I391_I1.1860.68
137_K141_N1.1860.68
587_D664_S1.1840.68
692_A696_K1.1790.67
579_Y586_V1.1790.67
570_A573_I1.1780.67
579_Y679_L1.1720.67
365_R394_D1.1710.67
455_A464_Q1.1700.67
602_E672_L1.1630.66
622_H756_D1.1620.66
394_D414_Y1.1610.66
196_L498_S1.1530.66
280_Y284_L1.1490.65
327_T363_G1.1420.65
443_M530_L1.1400.65
452_G455_A1.1340.64
367_N395_E1.1300.64
42_R46_A1.1280.64
326_Y355_V1.1250.64
177_Q197_E1.1250.64
244_F344_L1.1210.63
727_Q755_D1.1160.63
243_T289_D1.1150.63
194_L198_A1.1150.63
649_P661_V1.1140.63
236_N250_L1.1140.63
14_A291_A1.1130.63
34_T42_R1.1130.63
380_E385_G1.1100.63
193_L200_Q1.1100.63
41_L71_K1.1070.62
115_L119_W1.1040.62
586_V653_Q1.1040.62
241_P279_F1.1020.62
48_A201_K1.0990.62
723_R755_D1.0980.62
106_E177_Q1.0960.62
242_Q246_Q1.0960.62
163_R175_Q1.0960.62
535_H583_I1.0940.61
725_A735_L1.0940.61
375_L702_R1.0900.61
10_T14_A1.0890.61
364_V374_F1.0880.61
106_E114_E1.0880.61
277_L342_N1.0860.61
54_V232_I1.0850.61
229_I232_I1.0840.61
130_G214_A1.0830.61
437_F472_Y1.0820.61
466_R470_S1.0800.60
462_L596_H1.0750.60
244_F289_D1.0730.60
211_E227_L1.0690.60
727_Q731_D1.0680.60
539_G543_E1.0680.60
42_R310_L1.0660.59
277_L344_L1.0640.59
546_R571_R1.0600.59
228_T245_W1.0590.59
19_I299_S1.0580.59
201_K204_L1.0570.59
231_E235_H1.0560.59
440_L529_N1.0530.58
570_A575_R1.0510.58
160_D427_R1.0510.58
178_Q181_Q1.0500.58
280_Y344_L1.0450.58
18_E22_E1.0350.57
654_D761_T1.0300.57
92_Q313_T1.0280.57
463_E467_A1.0250.56
570_A574_N1.0250.56
164_L226_L1.0240.56
474_T604_Y1.0230.56
63_L248_C1.0220.56
47_T257_I1.0200.56
169_L227_L1.0190.56
598_C602_E1.0180.56
25_L29_A1.0160.56
204_L207_A1.0150.56
133_T478_E1.0130.55
77_M310_L1.0130.55
399_P414_Y1.0130.55
203_I207_A1.0050.55
207_A230_A1.0050.55
587_D657_G1.0010.55
458_Y462_L0.9960.54
87_L91_D0.9960.54
45_K48_A0.9880.54
440_L530_L0.9880.54
366_T370_I0.9850.53
383_R694_L0.9850.53
103_I117_P0.9840.53
461_L534_L0.9840.53
455_A544_Q0.9840.53
47_T77_M0.9820.53
657_G664_S0.9820.53
540_M546_R0.9810.53
583_I586_V0.9790.53
48_A197_E0.9750.53
451_E455_A0.9750.53
365_R414_Y0.9740.52
726_Q754_Q0.9720.52
538_K589_I0.9720.52
585_E589_I0.9710.52
86_L89_E0.9690.52
257_I495_L0.9660.52
678_L711_H0.9610.51
210_A214_A0.9610.51
27_Y31_H0.9590.51
297_L469_I0.9550.51
723_R727_Q0.9500.51
273_D344_L0.9500.51
320_A519_F0.9490.51
272_F328_A0.9470.50
211_E230_A0.9460.50
29_A49_Y0.9450.50
327_T390_Q0.9440.50
465_I530_L0.9440.50
470_S596_H0.9440.50
540_M572_L0.9440.50
747_V754_Q0.9440.50
50_I225_E0.9420.50
479_G482_I0.9410.50
658_P679_L0.9380.50
10_T380_E0.9360.50
364_V378_T0.9350.50
690_G693_G0.9340.49
518_N608_R0.9280.49
162_P166_N0.9280.49
377_K380_E0.9270.49
341_V346_F0.9260.49
297_L344_L0.9240.49
180_C193_L0.9230.49
658_P681_V0.9220.49
684_T687_T0.9180.48
424_I517_Y0.9170.48
624_P750_S0.9170.48
540_M544_Q0.9130.48
47_T86_L0.9120.48
559_N699_D0.9120.48
341_V370_I0.9100.48
629_V632_T0.9070.47
242_Q245_W0.9070.47
447_L461_L0.9050.47
90_L103_I0.9050.47
330_L374_F0.9050.47
539_G578_K0.9040.47
414_Y679_L0.9000.47
569_R631_A0.8990.47
545_Q571_R0.8960.47
454_A543_E0.8950.46
544_Q566_E0.8950.46
465_I469_I0.8940.46
627_S752_E0.8890.46
38_P41_L0.8890.46
243_T282_T0.8880.46
214_A227_L0.8860.46
579_Y616_S0.8860.46
230_A239_H0.8850.46
86_L310_L0.8830.46
394_D413_D0.8830.46
705_T709_L0.8830.46
334_T340_A0.8820.45
681_V763_H0.8800.45
591_A669_D0.8790.45
460_G463_E0.8780.45
397_V414_Y0.8780.45
276_M348_C0.8770.45
227_L231_E0.8770.45
297_L347_L0.8770.45
31_H43_R0.8760.45
589_I593_L0.8750.45
527_I531_S0.8750.45
163_R501_S0.8740.45
751_K754_Q0.8730.45
28_T118_Y0.8720.45
539_G577_E0.8710.45
658_P683_F0.8710.45
569_R573_I0.8690.45
273_D330_L0.8660.44
272_F301_W0.8660.44
738_R760_R0.8650.44
462_L466_R0.8630.44
581_N660_A0.8610.44
178_Q463_E0.8570.44
32_R105_E0.8560.44
103_I112_R0.8550.43
43_R52_E0.8530.43
224_E227_L0.8530.43
400_A674_S0.8530.43
588_N591_A0.8510.43
170_G227_L0.8500.43
211_E215_A0.8470.43
470_S604_Y0.8460.43
18_E71_K0.8430.43
131_Q486_G0.8420.42
319_F487_H0.8400.42
62_E65_A0.8380.42
739_V757_I0.8380.42
32_R36_G0.8380.42
442_V472_Y0.8370.42
693_G696_K0.8370.42
569_R572_L0.8370.42
499_F546_R0.8360.42
581_N664_S0.8340.42
251_F272_F0.8330.42
724_E727_Q0.8330.42
284_L288_E0.8320.42
451_E567_K0.8320.42
422_L710_Q0.8310.42
658_P700_F0.8310.42
215_A227_L0.8280.41
274_Q344_L0.8280.41
465_I593_L0.8280.41
582_D759_R0.8270.41
269_L304_C0.8260.41
741_G760_R0.8250.41
90_L112_R0.8240.41
401_F674_S0.8240.41
166_N545_Q0.8220.41
80_E119_W0.8210.41
333_L340_A0.8190.41
160_D172_L0.8170.41
28_T119_W0.8140.40
458_Y629_V0.8120.40
170_G174_A0.8110.40
62_E303_K0.8100.40
535_H576_F0.8100.40
460_G464_Q0.8090.40
586_V589_I0.8060.40
112_R117_P0.8050.40
568_V571_R0.8050.40
10_T376_M0.8050.40
477_V522_V0.8040.40
248_C276_M0.8040.40
475_L478_E0.8030.40
723_R758_I0.8020.40
717_V762_A0.8010.39
351_A355_V0.8000.39
51_L228_T0.7990.39
459_E592_E0.7980.39
139_A142_T0.7970.39
63_L292_F0.7960.39
369_L372_T0.7950.39
173_V200_Q0.7950.39
26_L30_S0.7930.39
346_F374_F0.7930.39
527_I590_S0.7890.39
274_Q328_A0.7890.39
428_T517_Y0.7880.39
169_L199_S0.7860.38
85_W312_S0.7830.38
28_T31_H0.7830.38
536_A576_F0.7820.38
522_V614_P0.7810.38
181_Q285_T0.7790.38
43_R46_A0.7750.38
720_D723_R0.7740.38
330_L396_V0.7720.37
502_D522_V0.7720.37
215_A254_M0.7710.37
353_Q380_E0.7700.37
131_Q489_D0.7700.37
73_R308_V0.7670.37
463_E466_R0.7650.37
277_L285_T0.7630.37
540_M574_N0.7630.37
745_F748_E0.7610.37
271_R274_Q0.7590.36
477_V612_F0.7590.36
375_L698_A0.7590.36
540_M578_K0.7570.36
433_D675_N0.7560.36
21_L25_L0.7550.36
334_T339_S0.7530.36
341_V367_N0.7530.36
605_Q612_F0.7530.36
289_D292_F0.7520.36
723_R726_Q0.7520.36
42_R90_L0.7510.36
318_Y321_G0.7510.36
458_Y592_E0.7510.36
27_Y40_I0.7490.36
138_A141_N0.7470.36
615_G675_N0.7460.36
120_E463_E0.7460.36
590_S668_L0.7450.35
167_H171_E0.7450.35
197_E200_Q0.7450.35
387_G648_S0.7440.35
366_T375_L0.7410.35
78_S309_L0.7410.35
234_R501_S0.7410.35
136_V478_E0.7400.35
595_R599_K0.7390.35
624_P753_I0.7380.35
285_T728_R0.7380.35
539_G576_F0.7370.35
31_H712_I0.7360.35
235_H250_L0.7350.35
242_Q286_Q0.7350.35
520_S606_N0.7350.35
29_A242_Q0.7350.35
634_D653_Q0.7330.35
101_F316_A0.7330.35
137_K181_Q0.7320.35
55_E61_E0.7320.35
177_Q180_C0.7320.35
430_G433_D0.7310.35
345_S364_V0.7310.35
527_I616_S0.7310.35
173_V180_C0.7300.34
657_G660_A0.7290.34
31_H306_D0.7280.34
284_L290_A0.7270.34
29_A53_H0.7270.34
649_P742_Y0.7260.34
89_E316_A0.7250.34
339_S367_N0.7250.34
22_E543_E0.7240.34
440_L632_T0.7230.34
243_T246_Q0.7230.34
51_L225_E0.7230.34
284_L287_G0.7210.34
289_D344_L0.7200.34
581_N587_D0.7180.34
88_K91_D0.7170.34
23_R80_E0.7170.34
203_I238_Q0.7150.33
622_H753_I0.7150.33
160_D501_S0.7140.33
231_E243_T0.7130.33
202_H205_R0.7110.33
634_D650_M0.7100.33
536_A633_P0.7100.33
43_R53_H0.7060.33
521_G615_G0.7050.33
30_S33_Q0.7040.33
169_L254_M0.7010.32
372_T459_E0.7000.32
239_H243_T0.7000.32
30_S45_K0.6990.32
644_D740_A0.6990.32
294_K351_A0.6980.32
619_V644_D0.6960.32
738_R741_G0.6960.32
63_L225_E0.6950.32
527_I594_L0.6950.32
194_L559_N0.6940.32
127_F490_W0.6930.32
361_N390_Q0.6910.32
385_G389_P0.6910.32
39_V42_R0.6910.32
20_S55_E0.6900.32
281_Q343_V0.6900.32
729_P735_L0.6890.32
754_Q758_I0.6880.32
660_A664_S0.6850.31
151_D312_S0.6840.31
225_E261_E0.6830.31
50_I122_R0.6820.31
165_L251_F0.6820.31
521_G619_V0.6820.31
535_H586_V0.6810.31
447_L451_E0.6800.31
378_T391_I0.6800.31
333_L367_N0.6790.31
368_A706_Q0.6780.31
582_D667_K0.6780.31
10_T694_L0.6770.31
58_I73_R0.6760.31
535_H589_I0.6750.31
242_Q603_K0.6740.31
430_G521_G0.6740.31
28_T32_R0.6730.31
504_L517_Y0.6730.31
11_A61_E0.6730.31
454_A571_R0.6720.31
572_L576_F0.6710.31
47_T111_Y0.6710.31
338_R566_E0.6700.30
294_K354_S0.6680.30
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401_F422_L0.6680.30
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577_E583_I0.6620.30
755_D759_R0.6620.30
721_T762_A0.6620.30
245_W289_D0.6610.30
318_Y624_P0.6610.30
214_A231_E0.6610.30
251_F276_M0.6600.30
133_T136_V0.6600.30
165_L171_E0.6600.30
236_N241_P0.6600.30
350_D353_Q0.6590.30
106_E112_R0.6570.30
544_Q567_K0.6570.30
682_K719_A0.6570.30
560_F576_F0.6560.30
80_E273_D0.6550.29
166_N240_K0.6550.29
457_T720_D0.6540.29
282_T689_E0.6540.29
197_E201_K0.6530.29
300_L681_V0.6530.29
581_N657_G0.6520.29
439_L469_I0.6500.29
469_I596_H0.6490.29
226_L257_I0.6480.29
730_Q754_Q0.6480.29
502_D517_Y0.6480.29
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593_L596_H0.6460.29
223_R575_R0.6460.29
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32_R53_H0.6410.29
365_R615_G0.6400.29
538_K585_E0.6400.29
581_N654_D0.6390.28
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322_F618_T0.6250.28
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601_V614_P0.6200.27
235_H253_Y0.6190.27
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626_G638_A0.6180.27
701_L714_F0.6170.27
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181_Q286_Q0.6130.27
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177_Q208_E0.6130.27
248_C280_Y0.6110.27
22_E26_L0.6110.27
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211_E231_E0.6100.27
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376_M691_E0.6090.27
454_A460_G0.6090.27
684_T762_A0.6080.27
393_N414_Y0.6070.27
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158_I415_S0.6050.26
311_R358_P0.6050.26
424_I428_T0.6050.26
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605_Q609_G0.6040.26
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274_Q339_S0.6030.26
264_A493_V0.6030.26
30_S42_R0.6030.26
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370_I374_F0.6020.26
230_A296_L0.6020.26
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114_E178_Q0.6000.26
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243_T283_S0.6000.26
383_R690_G0.6000.26
540_M571_R0.6000.26
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663_K712_I0.5990.26
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105_E655_A0.5910.26
365_R744_A0.5900.26
303_K426_G0.5890.25
595_R731_D0.5890.25
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320_A750_S0.5880.25
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27_Y306_D0.5870.25
325_G361_N0.5860.25
333_L369_L0.5860.25
352_Y390_Q0.5860.25
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44_A104_S0.5850.25
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52_E231_E0.5840.25
524_G616_S0.5840.25
746_F754_Q0.5840.25
523_Q675_N0.5840.25
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178_Q559_N0.5840.25
459_E588_N0.5830.25
388_I651_L0.5830.25
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298_E351_A0.5800.25
175_Q502_D0.5800.25
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383_R688_L0.5720.25
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240_K279_F0.5720.25
703_A707_L0.5700.24
171_E175_Q0.5700.24
734_G747_V0.5690.24
253_Y257_I0.5690.24
169_L690_G0.5690.24
422_L479_G0.5680.24
486_G490_W0.5680.24
456_L542_F0.5680.24
726_Q734_G0.5680.24
704_F712_I0.5680.24
680_N713_Q0.5680.24
86_L90_L0.5670.24
10_T88_K0.5650.24
31_H73_R0.5650.24
313_T415_S0.5650.24
739_V760_R0.5650.24
69_T76_I0.5640.24
227_L230_A0.5640.24
329_L365_R0.5640.24
248_C463_E0.5640.24
206_Y210_A0.5640.24
40_I71_K0.5620.24
272_F425_P0.5620.24
41_L45_K0.5620.24
259_Q324_T0.5620.24
522_V612_F0.5620.24
309_L522_V0.5610.24
329_L415_S0.5610.24
461_L537_L0.5600.24
438_N629_V0.5600.24
598_C601_V0.5600.24
294_K350_D0.5600.24
439_L447_L0.5590.24
572_L641_Q0.5590.24
244_F296_L0.5580.24
215_A224_E0.5570.24
154_Q265_S0.5570.24
529_N650_M0.5570.24
700_F709_L0.5560.24
429_Y518_N0.5560.24
298_E354_S0.5560.24
582_D679_L0.5560.24
164_L251_F0.5550.24
582_D631_A0.5550.24
458_Y534_L0.5540.24
453_N544_Q0.5540.24
713_Q740_A0.5540.24
39_V101_F0.5530.23
446_C461_L0.5530.23
536_A542_F0.5520.23
181_Q727_Q0.5510.23
277_L343_V0.5510.23
199_S203_I0.5510.23
561_A637_F0.5510.23
412_R492_P0.5510.23
709_L714_F0.5500.23
291_A460_G0.5500.23
22_E76_I0.5500.23
114_E117_P0.5500.23
317_R627_S0.5500.23
300_L304_C0.5490.23
353_Q384_F0.5490.23
230_A235_H0.5490.23
79_P86_L0.5480.23
23_R31_H0.5480.23
325_G390_Q0.5480.23
385_G468_K0.5480.23
538_K561_A0.5470.23
127_F489_D0.5470.23
292_F296_L0.5460.23
85_W151_D0.5460.23
25_L115_L0.5450.23
114_E133_T0.5450.23
607_P675_N0.5440.23
23_R79_P0.5440.23
210_A379_A0.5440.23
19_I28_T0.5430.23
16_T102_A0.5430.23
586_V634_D0.5430.23
126_D280_Y0.5420.23
82_D85_W0.5420.23
153_G500_I0.5410.23
688_L701_L0.5410.23
320_A477_V0.5410.23
174_A568_V0.5410.23
681_V714_F0.5410.23
654_D660_A0.5400.23
615_G621_A0.5400.23
670_N677_T0.5400.23
225_E495_L0.5390.23
178_Q285_T0.5390.23
443_M465_I0.5390.23
162_P413_D0.5390.23
393_N710_Q0.5390.23
626_G636_R0.5390.23
599_K672_L0.5380.23
658_P662_L0.5380.23
156_H417_V0.5380.23
197_E446_C0.5380.23
22_E280_Y0.5370.23
165_L279_F0.5370.23
452_G567_K0.5370.23
67_N73_R0.5370.23
517_Y631_A0.5360.23
465_I468_K0.5350.22
170_G173_V0.5340.22
412_R669_D0.5340.22
320_A726_Q0.5340.22
205_R503_C0.5340.22
88_K458_Y0.5340.22
242_Q631_A0.5330.22
215_A666_S0.5330.22
205_R209_L0.5320.22
433_D615_G0.5320.22
284_L343_V0.5320.22
101_F504_L0.5300.22
323_P361_N0.5300.22
447_L756_D0.5290.22
648_S661_V0.5290.22
281_Q466_R0.5270.22
51_L78_S0.5270.22
739_V761_T0.5270.22
546_R568_V0.5270.22
156_H421_E0.5260.22
253_Y761_T0.5260.22
84_Y87_L0.5260.22
277_L282_T0.5260.22
598_C614_P0.5260.22
477_V601_V0.5250.22
227_L239_H0.5250.22
175_Q638_A0.5250.22
715_N729_P0.5240.22
142_T469_I0.5240.22
169_L173_V0.5240.22
30_S49_Y0.5230.22
632_T735_L0.5230.22
307_I756_D0.5220.22
20_S68_R0.5220.22
178_Q288_E0.5220.22
263_N491_A0.5210.22
51_L202_H0.5210.22
559_N640_E0.5210.22
379_A694_L0.5210.22
297_L467_A0.5210.22
696_K704_F0.5210.22
391_I416_V0.5210.22
320_A624_P0.5210.22
205_R210_A0.5200.22
442_V445_I0.5200.22
650_M674_S0.5190.22
290_A595_R0.5180.22
114_E197_E0.5180.22
229_I299_S0.5180.22
58_I229_I0.5180.22
205_R502_D0.5170.22
130_G225_E0.5170.22
224_E231_E0.5170.22
224_E291_A0.5160.21
432_H518_N0.5150.21
584_D692_A0.5150.21
711_H715_N0.5140.21
214_A230_A0.5140.21
330_L562_T0.5140.21
84_Y151_D0.5140.21
272_F300_L0.5130.21
387_G734_G0.5130.21
377_K385_G0.5130.21
330_L348_C0.5130.21
45_K103_I0.5130.21
53_H78_S0.5120.21
442_V465_I0.5120.21
138_A178_Q0.5120.21
685_P715_N0.5120.21
579_Y665_V0.5120.21
414_Y681_V0.5110.21
31_H58_I0.5110.21
31_H39_V0.5110.21
592_E600_E0.5110.21
119_W344_L0.5100.21
582_D734_G0.5100.21
604_Y612_F0.5100.21
200_Q237_A0.5100.21
263_N676_G0.5090.21
340_A413_D0.5090.21
679_L710_Q0.5090.21
35_E42_R0.5080.21
680_N740_A0.5080.21
265_S436_M0.5080.21
14_A175_Q0.5070.21
467_A471_H0.5070.21
210_A385_G0.5070.21
282_T699_D0.5060.21
106_E285_T0.5060.21
214_A225_E0.5060.21
619_V675_N0.5060.21
84_Y88_K0.5060.21
350_D663_K0.5050.21
89_E263_N0.5050.21
366_T630_G0.5050.21
623_V756_D0.5050.21
224_E712_I0.5050.21
433_D619_V0.5040.21
106_E118_Y0.5040.21
178_Q460_G0.5030.21
77_M196_L0.5030.21
20_S75_G0.5030.21
700_F705_T0.5030.21
32_R117_P0.5020.21
315_S523_Q0.5020.21
177_Q604_Y0.5010.21
348_C351_A0.5010.21
726_Q758_I0.5000.21
683_F687_T0.5000.21
274_Q345_S0.5000.21
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
5a0uA 2 0.9935 100 0.08 Contact Map
2y8nA 2 0.9935 100 0.084 Contact Map
1r9dA 2 0.9908 100 0.094 Contact Map
2f3oA 3 0.9791 100 0.097 Contact Map
4pkfA 2 0.9778 100 0.114 Contact Map
1h16A 2 0.8941 100 0.26 Contact Map
1h7bA 2 0.617 100 0.888 Contact Map
4u3eA 2 0.7176 99.6 0.938 Contact Map
4x2uA 1 0.1869 63.8 0.985 Contact Map
3b34A 1 0.1882 37.6 0.987 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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