GREMLIN Database
PTFX2 - Multiphosphoryl transfer protein 2
UniProt: P32670 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11906
Length: 833 (662)
Sequences: 910 (606)
Seq/√Len: 23.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
605_H633_D7.0801.00
290_G332_I6.6821.00
512_L557_E5.9461.00
598_D602_Q5.1581.00
483_T520_E4.7841.00
486_L518_L4.7201.00
629_G661_L4.6111.00
436_A441_I4.5971.00
132_L330_I4.2181.00
664_A676_L4.0201.00
587_N674_E3.8831.00
158_A212_A3.8381.00
422_E491_R3.7861.00
600_A611_I3.6871.00
511_I558_I3.6101.00
625_P657_C3.5821.00
472_V514_V3.5721.00
506_S546_S3.5431.00
572_L596_A3.2581.00
314_L339_I3.1801.00
628_V649_M3.1561.00
269_I332_I3.1401.00
376_A653_D3.1311.00
612_G634_E3.0991.00
379_I633_D3.0651.00
548_M596_A3.0441.00
613_L632_L3.0411.00
227_S242_R2.9841.00
579_N582_V2.9101.00
450_G466_F2.8950.99
314_L334_G2.8880.99
159_L201_L2.7850.99
483_T521_A2.7820.99
422_E484_T2.7640.99
329_T348_A2.7320.99
379_I654_S2.7280.99
619_A637_M2.7160.99
499_K537_Q2.6580.99
331_Y351_Y2.6500.99
542_L547_V2.6410.99
563_I600_A2.6030.99
669_T672_E2.5970.99
454_V458_N2.4930.98
151_G154_A2.4810.98
469_Y477_E2.4540.98
83_W88_F2.4340.98
209_L213_E2.3730.98
422_E487_R2.3360.98
9_C58_T2.3320.98
380_R402_E2.3260.98
668_R672_E2.2620.97
281_L313_T2.2550.97
9_C64_C2.2530.97
652_L657_C2.2450.97
519_A535_K2.2230.97
448_I454_V2.1950.96
58_T64_C2.1850.96
131_I266_Q2.1630.96
426_Y491_R2.1350.96
271_M330_I2.1290.96
31_S72_D2.1270.96
430_C434_E2.1250.96
269_I290_G2.0900.95
32_S72_D2.0580.95
166_V169_N2.0510.95
654_S658_R2.0460.95
233_Y579_N2.0450.95
521_A524_Q2.0380.95
630_L664_A2.0340.95
490_L518_L2.0330.94
348_A352_Q2.0310.94
542_L554_C1.9710.94
463_A578_D1.9620.93
118_I317_V1.9610.93
155_E158_A1.9540.93
129_G348_A1.9410.93
502_I514_V1.9130.92
548_M551_I1.9090.92
601_V605_H1.9060.92
392_E547_V1.9030.92
155_E166_V1.8790.92
448_I458_N1.8730.92
167_L193_G1.8560.91
66_L84_L1.8440.91
508_M557_E1.8420.91
664_A667_C1.8390.91
547_V554_C1.8350.91
476_E513_W1.8340.91
30_F76_A1.8280.91
291_L306_A1.8260.91
619_A645_A1.8150.90
472_V505_I1.8150.90
552_D606_R1.8090.90
122_T334_G1.8070.90
489_I498_L1.8060.90
74_Q78_Q1.7960.90
264_L268_A1.7840.89
423_S491_R1.7830.89
23_V47_A1.7760.89
162_G166_V1.7660.89
515_K557_E1.7550.89
549_F596_A1.7530.89
629_G664_A1.7360.88
367_V542_L1.7310.88
414_M423_S1.7110.87
133_T264_L1.7100.87
448_I496_G1.7030.87
151_G155_E1.6930.87
273_D295_S1.6850.87
212_A253_Y1.6850.87
625_P652_L1.6830.86
630_L661_L1.6800.86
156_Q202_L1.6650.86
162_G169_N1.6650.86
442_I612_G1.6480.85
160_E202_L1.6360.85
551_I603_A1.6340.85
384_A403_G1.6290.85
15_V23_V1.6210.84
588_S617_L1.6170.84
223_C227_S1.6160.84
653_D656_E1.6060.84
215_I248_L1.5890.83
233_Y236_E1.5800.83
155_E162_G1.5770.83
8_I63_N1.5770.83
170_I189_R1.5590.82
399_N643_P1.5520.82
551_I604_V1.5500.81
626_L677_L1.5420.81
416_R424_E1.5320.81
502_I538_L1.5270.80
267_P289_K1.5190.80
599_Y603_A1.5130.80
233_Y582_V1.5060.80
307_R404_V1.5050.79
166_V170_I1.5040.79
575_V585_H1.4960.79
330_I339_I1.4910.79
81_S85_R1.4860.79
219_A245_C1.4830.78
151_G158_A1.4800.78
40_R62_D1.4620.77
339_I509_E1.4620.77
334_G484_T1.4580.77
383_I646_K1.4440.77
352_Q355_A1.4430.77
443_V489_I1.4350.76
508_M554_C1.4310.76
166_V173_R1.4310.76
667_C676_L1.4240.76
393_A397_F1.4150.75
277_P402_E1.4110.75
244_V466_F1.4080.75
133_T268_A1.4050.75
374_R380_R1.4040.74
198_R201_L1.3940.74
71_A75_E1.3830.73
7_F89_P1.3830.73
518_L538_L1.3740.73
34_I47_A1.3700.73
156_Q206_S1.3670.72
553_Q595_R1.3650.72
373_A402_E1.3630.72
423_S427_N1.3600.72
404_V619_A1.3560.72
76_A79_R1.3530.72
618_G635_L1.3480.71
316_G492_A1.3430.71
158_A162_G1.3410.71
129_G349_R1.3290.70
152_V155_E1.3270.70
334_G491_R1.3250.70
475_Y482_F1.3150.69
551_I561_F1.3130.69
279_Q334_G1.3120.69
626_L630_L1.3090.69
502_I518_L1.3040.69
610_W634_E1.3030.69
598_D662_N1.2990.68
303_V313_T1.2960.68
243_D278_S1.2910.68
233_Y616_E1.2910.68
500_I617_L1.2880.68
294_K318_D1.2860.68
236_E469_Y1.2850.68
477_E581_K1.2820.67
382_E610_W1.2800.67
171_E175_L1.2770.67
409_T486_L1.2740.67
159_L162_G1.2710.67
469_Y582_V1.2680.67
663_Q676_L1.2590.66
9_C24_E1.2540.66
373_A650_A1.2500.65
30_F48_K1.2470.65
382_E442_I1.2440.65
27_C34_I1.2330.64
149_A210_S1.2300.64
438_G497_S1.2280.64
233_Y585_H1.2180.63
52_A226_F1.2110.63
656_E659_K1.2080.63
594_L673_V1.2070.63
540_I626_L1.2050.62
130_G267_P1.2020.62
169_N251_Q1.1990.62
132_L324_P1.1980.62
520_E524_Q1.1960.62
84_L87_E1.1840.61
423_S426_Y1.1820.61
403_G440_S1.1810.61
558_I609_K1.1790.61
239_L276_T1.1770.61
266_Q287_H1.1730.60
381_I628_V1.1720.60
284_D288_L1.1700.60
280_F284_D1.1680.60
271_M642_I1.1630.60
573_L590_N1.1630.60
344_G347_V1.1620.60
328_Q342_E1.1610.60
31_S71_A1.1530.59
563_I611_I1.1430.58
205_V211_C1.1420.58
565_S613_L1.1390.58
220_N224_E1.1360.58
601_V611_I1.1350.58
407_F432_A1.1290.57
317_V421_G1.1290.57
549_F572_L1.1260.57
82_Q86_D1.1230.57
509_E669_T1.1220.57
443_V498_L1.1210.57
166_V251_Q1.1200.57
548_M572_L1.1120.56
245_C492_A1.1030.56
52_A331_Y1.1020.56
210_S213_E1.1020.56
466_F501_M1.1000.55
624_L645_A1.0990.55
576_D600_A1.0970.55
471_A593_F1.0960.55
390_S428_I1.0950.55
648_R652_L1.0940.55
292_L339_I1.0920.55
84_L88_F1.0850.54
329_T505_I1.0840.54
151_G162_G1.0820.54
373_A400_G1.0780.54
270_C366_R1.0780.54
52_A269_I1.0770.54
317_V330_I1.0760.54
124_C150_K1.0760.54
162_G170_I1.0740.54
384_A634_E1.0680.53
551_I600_A1.0670.53
228_R260_A1.0640.53
540_I554_C1.0640.53
442_I610_W1.0630.53
660_L676_L1.0630.53
163_L176_D1.0580.52
446_M476_E1.0550.52
241_V404_V1.0550.52
152_V158_A1.0520.52
173_R247_Q1.0460.52
371_Q650_A1.0440.51
212_A252_I1.0430.51
264_L267_P1.0410.51
11_L280_F1.0390.51
191_L350_Y1.0380.51
201_L248_L1.0380.51
33_Q46_N1.0380.51
347_V351_Y1.0370.51
335_N358_Q1.0360.51
510_E563_I1.0330.51
11_L89_P1.0260.50
26_L29_T1.0250.50
65_Q274_E1.0240.50
103_L271_M1.0210.50
493_S496_G1.0210.50
368_W371_Q1.0210.50
379_I658_R1.0200.50
243_D277_P1.0180.50
288_L311_I1.0170.50
308_S311_I1.0160.49
603_A612_G1.0130.49
11_L53_L1.0120.49
419_A456_Y1.0120.49
244_V280_F1.0100.49
233_Y575_V1.0060.49
30_F72_D1.0060.49
280_F309_F1.0050.49
389_H392_E1.0040.49
307_R616_E1.0030.49
308_S536_I1.0010.48
515_K519_A1.0010.48
601_V633_D1.0010.48
265_T268_A1.0000.48
280_F302_T0.9970.48
624_L649_M0.9950.48
108_V111_T0.9910.48
483_T517_K0.9890.48
167_L170_I0.9880.48
407_F637_M0.9880.48
166_V247_Q0.9880.48
265_T287_H0.9870.47
97_E546_S0.9860.47
292_L332_I0.9850.47
187_A275_L0.9840.47
158_A169_N0.9830.47
482_F548_M0.9790.47
453_P578_D0.9780.47
558_I579_N0.9770.47
95_L546_S0.9770.47
563_I601_V0.9750.47
27_C48_K0.9740.47
542_L558_I0.9730.46
487_R524_Q0.9710.46
155_E169_N0.9710.46
547_V611_I0.9690.46
482_F514_V0.9690.46
167_L189_R0.9680.46
134_P326_Q0.9670.46
661_L664_A0.9660.46
366_R369_L0.9660.46
54_I88_F0.9640.46
597_L632_L0.9640.46
404_V492_A0.9610.46
314_L332_I0.9590.45
11_L90_H0.9590.45
383_I637_M0.9560.45
516_E520_E0.9550.45
413_Y489_I0.9550.45
135_I191_L0.9530.45
159_L674_E0.9530.45
29_T497_S0.9520.45
336_A341_V0.9500.45
241_V585_H0.9490.45
511_I546_S0.9480.45
619_A641_S0.9470.45
172_F176_D0.9460.45
70_G76_A0.9450.44
522_K526_R0.9420.44
645_A649_M0.9410.44
667_C672_E0.9380.44
617_L638_S0.9370.44
302_T340_V0.9350.44
359_D363_E0.9340.44
269_I330_I0.9330.44
385_A396_A0.9320.44
433_L497_S0.9250.43
637_M645_A0.9250.43
95_L187_A0.9210.43
116_Q270_C0.9210.43
667_C673_V0.9210.43
345_E349_R0.9200.43
92_D96_A0.9190.43
317_V321_A0.9190.43
120_A555_C0.9190.43
587_N665_M0.9180.43
440_S676_L0.9170.43
166_V281_L0.9110.42
149_A155_E0.9100.42
655_R658_R0.9080.42
430_C505_I0.9070.42
418_S431_Q0.9070.42
653_D675_H0.9060.42
492_A637_M0.9060.42
327_Q363_E0.9060.42
350_Y354_E0.9050.42
185_L192_A0.9040.42
92_D95_L0.9030.42
169_N173_R0.9000.41
563_I632_L0.8990.41
83_W87_E0.8980.41
30_F80_L0.8970.41
612_G633_D0.8970.41
170_I173_R0.8970.41
327_Q630_L0.8960.41
618_G624_L0.8920.41
76_A416_R0.8920.41
245_C316_G0.8900.41
280_F288_L0.8880.41
213_E216_V0.8870.41
442_I634_E0.8860.40
175_L285_K0.8860.40
203_A546_S0.8840.40
380_R649_M0.8820.40
147_P244_V0.8810.40
46_N365_Q0.8790.40
506_S511_I0.8780.40
589_L601_V0.8750.40
84_L575_V0.8750.40
155_E211_C0.8730.40
27_C30_F0.8720.39
30_F79_R0.8710.39
7_F87_E0.8710.39
238_A466_F0.8690.39
175_L178_D0.8680.39
289_K475_Y0.8660.39
171_E189_R0.8650.39
50_A57_D0.8640.39
425_L488_S0.8630.39
174_L305_L0.8630.39
204_G209_L0.8620.39
623_V657_C0.8600.39
239_L544_V0.8590.39
344_G384_A0.8550.38
197_L219_A0.8540.38
579_N638_S0.8540.38
334_G337_G0.8510.38
83_W433_L0.8490.38
387_I393_A0.8480.38
45_G196_S0.8470.38
131_I327_Q0.8470.38
432_A441_I0.8450.38
163_L317_V0.8440.38
101_D104_E0.8440.38
275_L291_L0.8420.38
384_A610_W0.8420.38
381_I635_L0.8420.38
224_E227_S0.8410.37
382_E612_G0.8410.37
416_R583_T0.8410.37
129_G331_Y0.8380.37
414_M638_S0.8360.37
290_G309_F0.8350.37
375_T379_I0.8350.37
303_V446_M0.8340.37
328_Q656_E0.8340.37
190_S579_N0.8320.37
299_T478_Y0.8260.36
54_I575_V0.8250.36
675_H679_Q0.8250.36
155_E159_L0.8240.36
54_I616_E0.8220.36
484_T487_R0.8210.36
74_Q161_N0.8210.36
617_L623_V0.8190.36
293_L550_I0.8190.36
66_L573_L0.8180.36
381_I633_D0.8170.36
245_C466_F0.8170.36
582_V585_H0.8170.36
292_L616_E0.8160.36
45_G191_L0.8150.36
425_L504_M0.8130.36
548_M603_A0.8120.36
11_L23_V0.8100.35
130_G212_A0.8090.35
243_D290_G0.8070.35
407_F441_I0.8050.35
14_G18_R0.8020.35
506_S575_V0.8020.35
540_I588_S0.8010.35
653_D657_C0.7980.35
243_D402_E0.7960.35
356_R359_D0.7960.35
517_K542_L0.7940.34
404_V544_V0.7920.34
162_G252_I0.7920.34
373_A646_K0.7890.34
340_V347_V0.7890.34
16_H19_P0.7880.34
440_S499_K0.7880.34
433_L498_L0.7870.34
57_D315_V0.7870.34
392_E620_K0.7850.34
307_R544_V0.7850.34
549_F582_V0.7830.34
540_I664_A0.7810.34
546_S550_I0.7810.34
407_F616_E0.7810.34
482_F491_R0.7770.33
514_V518_L0.7730.33
671_L675_H0.7730.33
380_R439_R0.7730.33
317_V474_I0.7710.33
363_E367_V0.7710.33
363_E366_R0.7700.33
194_D647_A0.7690.33
457_L617_L0.7660.33
606_R628_V0.7650.33
276_T478_Y0.7650.33
28_N190_S0.7650.33
205_V649_M0.7630.32
292_L317_V0.7630.32
561_F603_A0.7610.32
353_Q659_K0.7600.32
392_E401_A0.7600.32
11_L87_E0.7600.32
185_L544_V0.7590.32
364_Q608_G0.7580.32
339_I606_R0.7570.32
525_L535_K0.7550.32
481_L518_L0.7550.32
548_M609_K0.7540.32
159_L163_L0.7540.32
184_I272_A0.7530.32
8_I97_E0.7490.32
9_C549_F0.7480.32
393_A640_P0.7480.32
11_L185_L0.7470.31
169_N247_Q0.7460.31
445_T475_Y0.7460.31
201_L326_Q0.7410.31
400_G646_K0.7410.31
628_V635_L0.7400.31
663_Q667_C0.7400.31
276_T493_S0.7400.31
483_T524_Q0.7390.31
166_V448_I0.7390.31
580_A601_V0.7340.31
463_A466_F0.7330.31
34_I48_K0.7330.31
188_H297_G0.7320.31
233_Y351_Y0.7310.31
36_W84_L0.7290.30
205_V354_E0.7290.30
359_D376_A0.7280.30
157_S161_N0.7270.30
24_E244_V0.7270.30
149_A152_V0.7240.30
281_L314_L0.7210.30
579_N585_H0.7200.30
155_E453_P0.7180.30
11_L88_F0.7170.30
331_Y448_I0.7160.30
474_I481_L0.7150.30
325_W328_Q0.7140.30
511_I603_A0.7140.30
72_D76_A0.7110.29
124_C207_A0.7110.29
237_R240_D0.7090.29
270_C281_L0.7090.29
422_E492_A0.7080.29
45_G52_A0.7070.29
160_E164_T0.7070.29
36_W66_L0.7060.29
544_V626_L0.7060.29
25_T54_I0.7060.29
398_G643_P0.7050.29
554_C609_K0.7050.29
279_Q293_L0.7040.29
23_V36_W0.7040.29
459_I507_S0.7040.29
185_L650_A0.7040.29
402_E436_A0.7030.29
303_V555_C0.7020.29
547_V600_A0.7020.29
373_A378_G0.7010.29
32_S508_M0.6990.29
62_D416_R0.6990.29
206_S542_L0.6990.29
244_V281_L0.6980.29
227_S346_A0.6970.29
128_A355_A0.6970.29
283_L288_L0.6960.28
190_S617_L0.6960.28
459_I474_I0.6940.28
221_H345_E0.6930.28
119_R599_Y0.6930.28
299_T593_F0.6920.28
455_D563_I0.6910.28
623_V632_L0.6910.28
202_L205_V0.6910.28
187_A302_T0.6890.28
85_R441_I0.6880.28
182_S587_N0.6870.28
201_L218_S0.6870.28
115_P191_L0.6860.28
269_I394_Q0.6860.28
277_P501_M0.6850.28
213_E616_E0.6850.28
383_I642_I0.6840.28
356_R360_A0.6840.28
426_Y430_C0.6840.28
80_L363_E0.6830.28
414_M511_I0.6830.28
411_M554_C0.6820.28
27_C76_A0.6820.28
363_E602_Q0.6820.28
397_F407_F0.6810.28
502_I536_I0.6800.28
122_T638_S0.6790.27
226_F575_V0.6790.27
241_V450_G0.6780.27
170_I508_M0.6770.27
309_F334_G0.6750.27
575_V582_V0.6750.27
49_S453_P0.6740.27
547_V551_I0.6740.27
265_T416_R0.6720.27
373_A384_A0.6720.27
248_L448_I0.6720.27
278_S283_L0.6720.27
166_V171_E0.6710.27
539_G560_F0.6710.27
51_L226_F0.6700.27
231_S642_I0.6690.27
279_Q313_T0.6690.27
278_S382_E0.6690.27
148_A175_L0.6690.27
589_L623_V0.6680.27
366_R643_P0.6670.27
36_W586_Y0.6670.27
439_R674_E0.6670.27
272_A416_R0.6670.27
602_Q659_K0.6650.27
504_M571_Y0.6650.27
163_L515_K0.6640.27
247_Q480_S0.6640.27
78_Q271_M0.6630.27
260_A342_E0.6610.26
156_Q160_E0.6610.26
519_A522_K0.6590.26
214_A494_A0.6570.26
313_T334_G0.6560.26
388_A414_M0.6550.26
235_Q242_R0.6540.26
87_E90_H0.6540.26
247_Q621_G0.6540.26
32_S638_S0.6540.26
99_K271_M0.6530.26
231_S521_A0.6530.26
575_V616_E0.6530.26
659_K663_Q0.6530.26
169_N178_D0.6530.26
279_Q589_L0.6520.26
271_M630_L0.6520.26
161_N199_E0.6510.26
269_I363_E0.6510.26
430_C495_H0.6510.26
575_V579_N0.6510.26
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372_Q650_A0.6420.25
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197_L236_E0.6410.25
277_P415_D0.6410.25
338_A592_A0.6400.25
426_Y505_I0.6400.25
68_I77_H0.6390.25
540_I561_F0.6390.25
293_L443_V0.6390.25
8_I495_H0.6380.25
334_G513_W0.6370.25
219_A501_M0.6370.25
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665_M669_T0.6330.25
352_Q356_R0.6320.25
161_N207_A0.6300.25
424_E583_T0.6300.25
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502_I569_T0.6290.25
93_A97_E0.6290.25
23_V506_S0.6290.25
77_H433_L0.6270.25
178_D186_E0.6270.25
382_E579_N0.6270.25
79_R299_T0.6260.25
212_A365_Q0.6250.25
484_T490_L0.6240.25
231_S455_D0.6240.25
658_R662_N0.6240.25
554_C592_A0.6230.24
193_G511_I0.6230.24
68_I73_E0.6220.24
191_L499_K0.6220.24
214_A500_I0.6220.24
244_V313_T0.6210.24
391_V427_N0.6210.24
37_H67_L0.6210.24
478_Y592_A0.6210.24
276_T416_R0.6200.24
277_P294_K0.6200.24
565_S659_K0.6200.24
25_T28_N0.6190.24
191_L520_E0.6190.24
482_F517_K0.6190.24
304_I307_R0.6190.24
129_G423_S0.6180.24
458_N578_D0.6180.24
508_M512_L0.6180.24
65_Q91_C0.6170.24
112_N223_C0.6160.24
156_Q159_L0.6160.24
396_A400_G0.6140.24
291_L639_A0.6130.24
159_L166_V0.6120.24
184_I281_L0.6120.24
17_A70_G0.6120.24
382_E601_V0.6120.24
249_L424_E0.6110.24
50_A302_T0.6110.24
118_I341_V0.6100.24
9_C233_Y0.6100.24
52_A292_L0.6100.24
316_G466_F0.6080.24
40_R43_R0.6070.24
152_V169_N0.6070.24
603_A609_K0.6060.24
106_L109_S0.6060.24
370_T392_E0.6050.24
147_P156_Q0.6040.23
274_E558_I0.6040.23
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600_A603_A0.6020.23
451_D504_M0.6020.23
100_S480_S0.6020.23
216_V220_N0.6010.23
293_L297_G0.6010.23
381_I606_R0.5990.23
32_S70_G0.5990.23
326_Q330_I0.5990.23
204_G217_A0.5980.23
118_I292_L0.5980.23
48_K540_I0.5980.23
364_Q367_V0.5970.23
401_A547_V0.5970.23
64_C272_A0.5960.23
75_E199_E0.5960.23
142_A216_V0.5960.23
336_A509_E0.5960.23
52_A387_I0.5950.23
173_R177_S0.5940.23
277_P315_V0.5930.23
388_A463_A0.5930.23
121_R668_R0.5920.23
173_R603_A0.5920.23
45_G209_L0.5910.23
7_F12_P0.5900.23
172_F266_Q0.5900.23
634_E673_V0.5900.23
272_A515_K0.5890.23
511_I540_I0.5890.23
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438_G633_D0.5880.23
222_F241_V0.5870.23
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662_N665_M0.5870.23
10_E24_E0.5860.23
235_Q575_V0.5860.23
373_A649_M0.5850.23
561_F604_V0.5820.22
186_E189_R0.5820.22
11_L453_P0.5820.22
473_R539_G0.5800.22
30_F592_A0.5800.22
308_S454_V0.5800.22
656_E672_E0.5800.22
247_Q576_D0.5790.22
197_L208_G0.5790.22
161_N345_E0.5780.22
263_K266_Q0.5780.22
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407_F454_V0.5780.22
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123_V126_G0.5760.22
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512_L515_K0.5750.22
554_C561_F0.5750.22
250_Q463_A0.5750.22
361_L505_I0.5750.22
637_M641_S0.5750.22
338_A341_V0.5750.22
402_E551_I0.5730.22
279_Q300_S0.5730.22
170_I463_A0.5730.22
431_Q659_K0.5730.22
500_I559_D0.5720.22
170_I306_A0.5710.22
173_R502_I0.5710.22
357_V517_K0.5710.22
672_E675_H0.5700.22
442_I501_M0.5700.22
187_A274_E0.5690.22
538_L656_E0.5690.22
71_A82_Q0.5690.22
395_A399_N0.5690.22
331_Y536_I0.5680.22
403_G425_L0.5680.22
643_P650_A0.5670.22
493_S534_E0.5670.22
165_L169_N0.5670.22
388_A578_D0.5670.22
342_E486_L0.5660.22
482_F596_A0.5660.22
142_A364_Q0.5660.22
223_C593_F0.5650.22
196_S520_E0.5650.22
267_P287_H0.5650.22
379_I505_I0.5650.22
237_R449_G0.5630.21
283_L610_W0.5630.21
409_T521_A0.5630.21
339_I608_G0.5630.21
297_G382_E0.5630.21
393_A436_A0.5620.21
598_D619_A0.5620.21
248_L582_V0.5620.21
304_I569_T0.5610.21
371_Q432_A0.5610.21
303_V334_G0.5610.21
411_M551_I0.5610.21
448_I623_V0.5610.21
428_I431_Q0.5600.21
542_L608_G0.5600.21
131_I267_P0.5590.21
433_L441_I0.5590.21
99_K103_L0.5590.21
14_G70_G0.5590.21
409_T619_A0.5580.21
23_V578_D0.5570.21
276_T307_R0.5570.21
243_D247_Q0.5570.21
276_T291_L0.5570.21
324_P427_N0.5560.21
25_T448_I0.5560.21
11_L514_V0.5550.21
203_A329_T0.5550.21
446_M479_A0.5540.21
626_L664_A0.5540.21
215_I219_A0.5530.21
203_A206_S0.5520.21
500_I662_N0.5520.21
14_G17_A0.5510.21
322_L547_V0.5510.21
441_I489_I0.5510.21
504_M591_P0.5500.21
153_D493_S0.5500.21
171_E349_R0.5500.21
388_A648_R0.5500.21
226_F443_V0.5490.21
556_E668_R0.5480.21
343_P563_I0.5460.21
55_G518_L0.5450.21
426_Y495_H0.5450.21
305_L411_M0.5450.21
474_I549_F0.5450.21
383_I565_S0.5440.21
432_A442_I0.5440.21
250_Q475_Y0.5440.21
245_C476_E0.5440.21
156_Q649_M0.5440.21
53_L190_S0.5440.21
433_L492_A0.5430.21
23_V80_L0.5420.21
321_A409_T0.5420.21
66_L366_R0.5410.20
340_V351_Y0.5410.20
219_A241_V0.5410.20
200_H482_F0.5400.20
240_D451_D0.5400.20
442_I448_I0.5400.20
128_A654_S0.5400.20
315_V318_D0.5380.20
235_Q241_V0.5380.20
493_S660_L0.5380.20
663_Q666_A0.5380.20
270_C293_L0.5370.20
230_S463_A0.5370.20
403_G488_S0.5360.20
11_L288_L0.5350.20
160_E168_K0.5350.20
172_F655_R0.5340.20
127_S355_A0.5340.20
589_L674_E0.5340.20
181_T579_N0.5340.20
109_S606_R0.5330.20
549_F669_T0.5330.20
460_P648_R0.5330.20
380_R398_G0.5330.20
68_I632_L0.5330.20
508_M558_I0.5320.20
168_K427_N0.5320.20
308_S445_T0.5320.20
309_F661_L0.5310.20
235_Q582_V0.5310.20
421_G486_L0.5310.20
32_S477_E0.5310.20
198_R360_A0.5310.20
302_T426_Y0.5290.20
9_C113_L0.5290.20
240_D452_K0.5290.20
185_L229_S0.5290.20
272_A423_S0.5280.20
15_V448_I0.5280.20
378_G635_L0.5280.20
132_L326_Q0.5280.20
257_R332_I0.5270.20
31_S509_E0.5270.20
129_G352_Q0.5270.20
200_H231_S0.5270.20
13_N578_D0.5260.20
108_V668_R0.5260.20
482_F582_V0.5260.20
244_V383_I0.5260.20
123_V618_G0.5260.20
554_C604_V0.5260.20
124_C492_A0.5260.20
496_G569_T0.5240.20
607_Q610_W0.5240.20
281_L316_G0.5240.20
563_I597_L0.5240.20
442_I599_Y0.5230.20
522_K535_K0.5230.20
210_S557_E0.5230.20
389_H421_G0.5230.20
13_N233_Y0.5230.20
365_Q644_A0.5230.20
279_Q644_A0.5220.20
512_L619_A0.5210.20
369_L565_S0.5200.20
416_R594_L0.5200.20
201_L215_I0.5200.20
427_N601_V0.5200.20
340_V616_E0.5200.20
160_E163_L0.5190.19
84_L459_I0.5190.19
99_K161_N0.5190.19
164_T345_E0.5190.19
390_S626_L0.5180.19
401_A501_M0.5180.19
300_S446_M0.5180.19
427_N431_Q0.5180.19
37_H65_Q0.5170.19
434_E658_R0.5160.19
339_I544_V0.5160.19
53_L57_D0.5160.19
432_A637_M0.5150.19
345_E394_Q0.5140.19
537_Q656_E0.5140.19
168_K207_A0.5130.19
12_P231_S0.5130.19
237_R451_D0.5110.19
244_V316_G0.5110.19
512_L668_R0.5110.19
150_K371_Q0.5110.19
21_S581_K0.5110.19
604_V611_I0.5100.19
16_H70_G0.5100.19
70_G73_E0.5100.19
422_E443_V0.5100.19
183_A356_R0.5090.19
13_N409_T0.5090.19
269_I555_C0.5090.19
226_F235_Q0.5080.19
281_L334_G0.5080.19
307_R569_T0.5070.19
170_I193_G0.5070.19
64_C84_L0.5070.19
429_F485_Q0.5070.19
184_I613_L0.5060.19
205_V493_S0.5050.19
547_V561_F0.5050.19
443_V550_I0.5040.19
234_L605_H0.5040.19
288_L482_F0.5040.19
385_A632_L0.5040.19
307_R638_S0.5040.19
433_L455_D0.5030.19
669_T673_V0.5030.19
358_Q361_L0.5020.19
154_A158_A0.5020.19
617_L627_L0.5020.19
15_V505_I0.5020.19
165_L352_Q0.5020.19
23_V308_S0.5010.19
436_A471_A0.5010.19
660_L663_Q0.5010.19
339_I613_L0.5000.19
552_D595_R0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2hwgA 2 0.6807 100 0.511 Contact Map
2wqdA 2 0.6783 100 0.512 Contact Map
1vbgA 2 0.7515 100 0.591 Contact Map
1kblA 2 0.7539 100 0.592 Contact Map
2x0sA 2 0.7635 100 0.601 Contact Map
2olsA 2 0.6363 100 0.653 Contact Map
2xz9A 2 0.3806 100 0.723 Contact Map
1zymA 2 0.2917 100 0.818 Contact Map
4l9zA 5 0.3541 100 0.865 Contact Map
3qqwA 3 0.3469 100 0.865 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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