GREMLIN Database
YIJF - Uncharacterized protein YijF
UniProt: P32668 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11903
Length: 205 (171)
Sequences: 309 (227)
Seq/√Len: 17.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
93_V125_L5.8331.00
44_R187_E3.7051.00
126_E197_V3.4171.00
126_E200_Y3.1950.99
153_W163_G3.0700.99
165_V177_V3.0090.99
166_S178_I2.9430.99
166_S187_E2.8790.98
58_V71_R2.6380.97
62_Y94_H2.4690.96
155_L181_I2.4560.95
44_R178_I2.3840.95
46_Q185_A2.3040.93
126_E154_R2.2730.93
62_Y95_E2.2570.93
126_E160_A2.1960.92
178_I187_E2.1950.92
103_E131_R2.1830.91
46_Q49_S2.1760.91
149_D201_R2.0230.88
54_D71_R1.9790.87
154_R157_N1.9580.86
152_S197_V1.9060.85
46_Q81_A1.8750.84
64_G169_F1.8550.83
79_I90_Q1.7980.81
78_V164_V1.7610.79
56_A60_L1.7370.78
155_L158_G1.7070.77
79_I94_H1.6910.76
54_D113_P1.6120.73
43_A164_V1.5960.72
55_P71_R1.5810.71
69_Q84_S1.5510.70
128_W202_Y1.5370.69
151_V191_L1.5000.67
139_S144_D1.4940.67
44_R166_S1.4730.66
80_R180_N1.3820.61
64_G187_E1.3780.60
82_L93_V1.3610.59
52_F70_E1.3490.59
66_D119_H1.3350.58
43_A81_A1.3140.57
152_S160_A1.2990.56
44_R167_D1.2680.54
154_R158_G1.2450.53
78_V86_K1.2170.51
163_G190_V1.2110.50
106_Q127_T1.2090.50
68_P180_N1.1980.50
167_D187_E1.1920.49
50_T60_L1.1890.49
168_G187_E1.1870.49
105_P131_R1.1860.49
74_C161_H1.1830.49
130_S135_T1.1770.48
154_R160_A1.1670.48
82_L128_W1.1670.48
100_N131_R1.1570.47
98_A178_I1.1560.47
42_G85_Q1.1520.47
58_V150_I1.1400.46
127_T130_S1.1300.46
154_R197_V1.1240.45
95_E99_K1.1140.45
174_T189_D1.1050.44
63_P184_G1.0890.43
106_Q111_K1.0750.42
151_V196_M1.0670.42
85_Q145_Y1.0540.41
170_A174_T1.0290.40
35_T38_A1.0250.39
112_R143_S1.0200.39
52_F71_R1.0040.38
37_L130_S1.0030.38
101_F108_W0.9970.38
150_I166_S0.9910.37
67_V94_H0.9890.37
83_R90_Q0.9830.37
90_Q94_H0.9740.36
137_P144_D0.9680.36
88_D91_K0.9440.35
73_V122_V0.9430.35
127_T150_I0.9420.35
55_P81_A0.9330.34
58_V167_D0.9270.34
86_K200_Y0.9270.34
90_Q119_H0.9200.34
40_A44_R0.9180.33
40_A169_F0.9140.33
61_T141_N0.9100.33
166_S175_P0.9090.33
115_S130_S0.9040.33
189_D202_Y0.9020.33
126_E158_G0.9010.33
161_H179_H0.9010.33
46_Q50_T0.9010.33
141_N144_D0.8930.32
79_I119_H0.8900.32
125_L129_F0.8860.32
63_P83_R0.8670.31
139_S145_Y0.8670.31
126_E156_D0.8630.31
73_V124_N0.8550.30
42_G84_S0.8550.30
164_V167_D0.8510.30
35_T85_Q0.8440.30
156_D159_L0.8420.29
144_D165_V0.8340.29
43_A176_L0.8300.29
91_K95_E0.8300.29
103_E193_N0.8270.29
126_E130_S0.8230.29
68_P80_R0.8210.28
152_S162_I0.8210.28
134_K202_Y0.8180.28
82_L125_L0.8160.28
137_P146_Q0.8120.28
103_E132_H0.8090.28
40_A75_S0.8050.28
51_L60_L0.8020.27
46_Q55_P0.7970.27
192_F202_Y0.7940.27
147_A175_P0.7920.27
75_S152_S0.7920.27
92_L128_W0.7810.26
77_V173_G0.7760.26
105_P123_P0.7760.26
192_F200_Y0.7760.26
136_R146_Q0.7750.26
47_I187_E0.7750.26
66_D90_Q0.7720.26
60_L186_Q0.7720.26
34_N37_L0.7700.26
125_L162_I0.7690.26
142_P146_Q0.7670.26
145_Y192_F0.7600.26
129_F145_Y0.7590.25
75_S194_W0.7560.25
190_V194_W0.7490.25
54_D182_G0.7460.25
139_S200_Y0.7460.25
80_R105_P0.7370.24
168_G176_L0.7350.24
74_C179_H0.7340.24
59_Q115_S0.7330.24
129_F151_V0.7320.24
138_T145_Y0.7310.24
43_A80_R0.7220.24
40_A178_I0.7160.24
160_A200_Y0.7140.23
43_A168_G0.7080.23
73_V77_V0.7060.23
38_A61_T0.7060.23
133_D187_E0.7030.23
115_S195_R0.7000.23
54_D183_A0.6980.23
47_I50_T0.6960.23
93_V158_G0.6960.23
85_Q186_Q0.6870.22
87_V92_L0.6860.22
49_S185_A0.6840.22
38_A132_H0.6840.22
92_L132_H0.6770.22
63_P90_Q0.6760.22
112_R199_H0.6750.22
141_N165_V0.6750.22
169_F173_G0.6730.22
45_Q49_S0.6720.22
59_Q147_A0.6700.22
140_K193_N0.6690.22
86_K128_W0.6590.21
164_V187_E0.6580.21
64_G202_Y0.6530.21
66_D83_R0.6520.21
72_G77_V0.6490.21
42_G82_L0.6430.21
87_V128_W0.6420.20
151_V198_G0.6410.20
154_R159_L0.6370.20
63_P66_D0.6330.20
73_V161_H0.6290.20
45_Q84_S0.6290.20
100_N167_D0.6270.20
151_V197_V0.6220.20
45_Q165_V0.6210.20
126_E152_S0.6190.20
139_S142_P0.6190.20
54_D184_G0.6160.19
102_A164_V0.6160.19
47_I82_L0.6110.19
191_L196_M0.6090.19
82_L85_Q0.6080.19
68_P123_P0.6070.19
129_F158_G0.6050.19
129_F155_L0.6030.19
149_D166_S0.6000.19
37_L141_N0.5990.19
102_A112_R0.5980.19
70_E165_V0.5970.19
139_S172_D0.5960.19
142_P145_Y0.5950.19
117_I149_D0.5930.19
150_I195_R0.5900.19
181_I184_G0.5890.18
78_V90_Q0.5870.18
160_A194_W0.5860.18
164_V171_R0.5860.18
110_L159_L0.5740.18
153_W194_W0.5690.18
98_A146_Q0.5660.18
50_T185_A0.5650.18
45_Q48_G0.5650.18
105_P184_G0.5620.18
191_L202_Y0.5620.18
115_S137_P0.5580.17
47_I185_A0.5560.17
141_N177_V0.5510.17
187_E201_R0.5500.17
39_I82_L0.5500.17
136_R201_R0.5470.17
40_A158_G0.5460.17
153_W196_M0.5460.17
88_D151_V0.5450.17
53_Y73_V0.5430.17
139_S192_F0.5390.17
45_Q102_A0.5370.17
65_G118_D0.5370.17
58_V61_T0.5350.17
82_L134_K0.5330.17
80_R94_H0.5300.16
123_P182_G0.5300.16
41_D137_P0.5290.16
113_P169_F0.5280.16
80_R182_G0.5260.16
47_I55_P0.5240.16
97_M110_L0.5230.16
50_T151_V0.5230.16
92_L100_N0.5220.16
105_P110_L0.5180.16
54_D181_I0.5170.16
101_F184_G0.5170.16
40_A166_S0.5170.16
32_Q35_T0.5160.16
33_A138_T0.5150.16
97_M113_P0.5140.16
59_Q95_E0.5120.16
78_V135_T0.5100.16
43_A166_S0.5090.16
184_G192_F0.5090.16
36_N141_N0.5080.16
79_I93_V0.5060.16
91_K122_V0.5060.16
47_I77_V0.5020.16
101_F105_P0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4hpeA 1 0.7171 97.4 0.914 Contact Map
3m1uA 2 0.7024 97.3 0.916 Contact Map
3npfA 2 0.7415 96.9 0.92 Contact Map
2k1gA 1 0.5902 96.6 0.922 Contact Map
4fdyA 1 0.722 96.2 0.926 Contact Map
4lj1A 1 0.5463 96.1 0.927 Contact Map
4xcmA 2 0.6976 95.5 0.93 Contact Map
4q4gX 1 0.7268 95.5 0.93 Contact Map
3h41A 1 0.7268 95.5 0.93 Contact Map
3pbiA 1 0.6976 95.3 0.931 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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