NUDC - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

NUDC - NADH pyrophosphatase

UniProt:	P32664	Sequences: MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11702
Length:	257 (227)
Sequences:	2168 (1562)
Seq/√Len:	103.7

ECOLI - NUDC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
154_H	222_E	5.053	1.00
176_M	182_K	4.352	1.00
242_R	246_E	3.842	1.00
185_N	207_E	3.578	1.00
137_R	140_S	3.465	1.00
167_L	202_T	3.314	1.00
134_A	141_I	3.049	1.00
184_K	209_D	2.868	1.00
103_H	117_S	2.753	1.00
105_M	114_M	2.693	1.00
98_C	101_C	2.591	1.00
101_C	116_C	2.547	1.00
98_C	116_C	2.505	1.00
172_A	186_L	2.493	1.00
167_L	204_F	2.466	1.00
106_Y	117_S	2.461	1.00
169_Q	172_A	2.458	1.00
182_K	209_D	2.443	1.00
135_I	175_V	2.373	1.00
145_Q	221_L	2.364	1.00
84_R	112_W	2.251	1.00
144_A	157_L	2.246	1.00
108_S	115_L	2.215	1.00
141_I	245_I	2.121	1.00
135_I	206_A	2.117	1.00
203_A	240_V	2.096	1.00
92_Y	114_M	2.047	1.00
140_S	227_R	1.993	1.00
234_L	242_R	1.971	1.00
179_S	223_A	1.935	1.00
101_C	119_C	1.925	1.00
161_V	167_L	1.891	1.00
184_K	207_E	1.868	1.00
189_V	247_D	1.831	1.00
172_A	184_K	1.796	1.00
157_L	179_S	1.796	1.00
75_D	78_L	1.789	1.00
246_E	250_A	1.769	1.00
94_S	100_Y	1.749	1.00
103_H	118_H	1.724	1.00
56_L	89_A	1.704	1.00
132_I	240_V	1.680	1.00
215_I	223_A	1.676	1.00
146_H	155_T	1.663	1.00
130_C	239_T	1.658	1.00
179_S	220_L	1.653	1.00
137_R	211_G	1.651	1.00
228_Y	248_T	1.526	1.00
208_Y	211_G	1.518	1.00
116_C	119_C	1.518	1.00
115_L	122_R	1.505	1.00
213_I	223_A	1.503	1.00
146_H	149_H	1.471	1.00
143_L	226_Y	1.471	1.00
171_V	183_V	1.465	1.00
167_L	200_L	1.461	1.00
156_V	244_L	1.448	1.00
32_E	35_N	1.442	1.00
67_S	70_Q	1.415	1.00
181_I	208_Y	1.410	1.00
133_V	206_A	1.390	1.00
98_C	119_C	1.381	1.00
156_V	203_A	1.367	1.00
139_D	228_Y	1.365	1.00
133_V	157_L	1.308	0.99
187_R	207_E	1.308	0.99
160_F	197_P	1.299	0.99
147_T	221_L	1.286	0.99
234_L	245_I	1.275	0.99
139_D	229_D	1.269	0.99
144_A	223_A	1.263	0.99
142_L	181_I	1.251	0.99
189_V	244_L	1.234	0.99
151_N	221_L	1.231	0.99
144_A	179_S	1.225	0.99
227_R	230_D	1.225	0.99
144_A	220_L	1.219	0.99
31_G	35_N	1.212	0.99
190_T	240_V	1.198	0.99
145_Q	222_E	1.198	0.99
161_V	170_A	1.191	0.99
90_E	94_S	1.190	0.99
189_V	205_M	1.175	0.99
96_K	104_E	1.174	0.98
232_P	249_V	1.173	0.98
139_D	227_R	1.161	0.98
95_H	123_Y	1.130	0.98
95_H	105_M	1.129	0.98
149_H	155_T	1.126	0.98
30_Y	35_N	1.121	0.98
28_L	31_G	1.120	0.98
217_P	220_L	1.100	0.98
145_Q	150_R	1.082	0.97
168_E	191_S	1.071	0.97
113_A	122_R	1.060	0.97
29_P	32_E	1.055	0.97
96_K	114_M	1.045	0.97
136_R	207_E	1.044	0.97
134_A	156_V	1.041	0.97
132_I	171_V	1.041	0.97
32_E	36_F	1.017	0.96
131_I	170_A	1.009	0.96
99_G	119_C	1.004	0.96
205_M	247_D	0.996	0.96
58_Q	93_R	0.985	0.96
102_G	105_M	0.979	0.95
132_I	203_A	0.977	0.95
86_V	90_E	0.971	0.95
92_Y	107_P	0.964	0.95
235_P	241_A	0.952	0.95
190_T	243_R	0.950	0.95
58_Q	89_A	0.945	0.94
135_I	156_V	0.940	0.94
201_M	240_V	0.935	0.94
130_C	199_S	0.931	0.94
146_H	220_L	0.930	0.94
149_H	153_V	0.928	0.94
150_R	153_V	0.924	0.94
87_Q	198_Q	0.922	0.94
133_V	171_V	0.922	0.94
224_N	230_D	0.921	0.94
133_V	175_V	0.916	0.93
38_L	41_Q	0.910	0.93
48_E	51_G	0.899	0.93
175_V	183_V	0.895	0.93
182_K	210_S	0.878	0.92
188_Y	191_S	0.876	0.92
215_I	218_K	0.874	0.92
154_H	226_Y	0.865	0.91
151_N	233_L	0.864	0.91
72_I	238_G	0.859	0.91
25_K	64_D	0.857	0.91
131_I	171_V	0.857	0.91
131_I	193_P	0.855	0.91
129_P	202_T	0.851	0.91
80_Q	169_Q	0.839	0.90
187_R	205_M	0.838	0.90
143_L	231_L	0.833	0.90
71_V	74_L	0.829	0.89
45_Q	48_E	0.829	0.89
141_I	156_V	0.828	0.89
105_M	123_Y	0.827	0.89
90_E	93_R	0.826	0.89
220_L	223_A	0.825	0.89
136_R	205_M	0.825	0.89
107_P	114_M	0.824	0.89
99_G	105_M	0.821	0.89
228_Y	249_V	0.819	0.89
95_H	114_M	0.816	0.89
214_V	217_P	0.812	0.89
163_V	198_Q	0.807	0.88
229_D	232_P	0.806	0.88
145_Q	151_N	0.804	0.88
154_H	224_N	0.797	0.88
72_I	130_C	0.797	0.88
246_E	249_V	0.794	0.87
37_D	60_Q	0.788	0.87
92_Y	105_M	0.785	0.87
87_Q	163_V	0.777	0.86
111_E	128_A	0.763	0.85
31_G	34_A	0.761	0.85
45_Q	55_W	0.761	0.85
28_L	32_E	0.760	0.85
205_M	251_M	0.760	0.85
79_F	83_G	0.757	0.85
130_C	204_F	0.756	0.85
171_V	204_F	0.747	0.84
126_Q	162_E	0.746	0.84
71_V	79_F	0.744	0.84
140_S	211_G	0.741	0.83
183_V	206_A	0.737	0.83
39_V	43_A	0.736	0.83
145_Q	223_A	0.734	0.83
95_H	99_G	0.733	0.83
164_G	191_S	0.733	0.83
146_H	221_L	0.732	0.83
156_V	239_T	0.728	0.82
80_Q	83_G	0.726	0.82
135_I	157_L	0.726	0.82
30_Y	33_A	0.725	0.82
106_Y	115_L	0.724	0.82
201_M	241_A	0.723	0.82
172_A	182_K	0.713	0.81
50_Q	62_R	0.711	0.81
30_Y	34_A	0.709	0.81
167_L	191_S	0.704	0.80
109_K	122_R	0.702	0.80
44_L	88_L	0.701	0.80
145_Q	152_G	0.699	0.80
145_Q	149_H	0.697	0.80
91_F	123_Y	0.697	0.80
152_G	233_L	0.696	0.80
243_R	247_D	0.692	0.79
97_Y	104_E	0.691	0.79
88_L	92_Y	0.691	0.79
28_L	35_N	0.687	0.79
190_T	239_T	0.682	0.78
94_S	198_Q	0.681	0.78
27_E	30_Y	0.680	0.78
237_P	246_E	0.680	0.78
131_I	166_T	0.680	0.78
104_E	117_S	0.677	0.78
132_I	183_V	0.677	0.78
161_V	204_F	0.677	0.78
168_E	188_Y	0.674	0.77
99_G	123_Y	0.674	0.77
108_S	113_A	0.673	0.77
153_V	233_L	0.672	0.77
128_A	199_S	0.671	0.77
34_A	37_D	0.665	0.76
128_A	198_Q	0.665	0.76
34_A	40_G	0.663	0.76
41_Q	61_R	0.663	0.76
247_D	250_A	0.661	0.76
235_P	242_R	0.655	0.75
166_T	190_T	0.653	0.75
189_V	243_R	0.653	0.75
156_V	226_Y	0.651	0.75
127_I	163_V	0.650	0.75
130_C	156_V	0.647	0.74
57_V	76_V	0.647	0.74
89_A	93_R	0.647	0.74
45_Q	49_W	0.646	0.74
37_D	40_G	0.646	0.74
27_E	32_E	0.645	0.74
40_G	43_A	0.643	0.74
132_I	241_A	0.643	0.74
170_A	249_V	0.642	0.74
137_R	210_S	0.639	0.73
113_A	130_C	0.635	0.73
33_A	43_A	0.632	0.73
29_P	33_A	0.631	0.73
99_G	245_I	0.628	0.72
134_A	244_L	0.626	0.72
183_V	186_L	0.625	0.72
130_C	161_V	0.625	0.72
232_P	245_I	0.619	0.71
29_P	34_A	0.619	0.71
65_M	89_A	0.619	0.71
99_G	121_E	0.618	0.71
29_P	35_N	0.617	0.71
232_P	251_M	0.613	0.70
188_Y	216_D	0.613	0.70
87_Q	195_P	0.613	0.70
84_R	163_V	0.613	0.70
156_V	181_I	0.612	0.70
136_R	139_D	0.611	0.70
91_F	110_T	0.610	0.70
100_Y	121_E	0.609	0.70
171_V	186_L	0.608	0.70
87_Q	90_E	0.606	0.70
88_L	163_V	0.606	0.70
124_Y	196_F	0.606	0.70
149_H	199_S	0.604	0.69
213_I	217_P	0.603	0.69
247_D	251_M	0.599	0.69
27_E	33_A	0.598	0.68
97_Y	102_G	0.597	0.68
152_G	221_L	0.597	0.68
140_S	230_D	0.595	0.68
186_L	204_F	0.593	0.68
167_L	193_P	0.592	0.68
48_E	52_E	0.592	0.68
66_G	70_Q	0.589	0.67
153_V	226_Y	0.587	0.67
35_N	38_L	0.585	0.67
77_G	81_L	0.582	0.66
28_L	36_F	0.577	0.66
122_R	175_V	0.573	0.65
111_E	122_R	0.572	0.65
126_Q	132_I	0.569	0.65
72_I	239_T	0.569	0.65
25_K	32_E	0.567	0.64
84_R	162_E	0.566	0.64
101_C	210_S	0.566	0.64
121_E	198_Q	0.565	0.64
43_A	57_V	0.563	0.64
26_G	40_G	0.562	0.64
133_V	172_A	0.562	0.64
42_R	58_Q	0.561	0.64
25_K	29_P	0.560	0.63
226_Y	245_I	0.560	0.63
103_H	121_E	0.559	0.63
161_V	188_Y	0.558	0.63
28_L	33_A	0.554	0.63
200_L	244_L	0.552	0.62
33_A	37_D	0.551	0.62
95_H	157_L	0.550	0.62
44_L	47_G	0.549	0.62
157_L	220_L	0.548	0.62
137_R	207_E	0.544	0.61
156_V	241_A	0.543	0.61
112_W	127_I	0.543	0.61
56_L	85_G	0.542	0.61
195_P	199_S	0.542	0.61
25_K	30_Y	0.540	0.61
37_D	41_Q	0.539	0.61
157_L	213_I	0.538	0.60
25_K	28_L	0.538	0.60
112_W	149_H	0.535	0.60
106_Y	118_H	0.534	0.60
136_R	141_I	0.530	0.59
134_A	248_T	0.530	0.59
133_V	179_S	0.530	0.59
45_Q	53_P	0.530	0.59
113_A	124_Y	0.529	0.59
190_T	229_D	0.527	0.59
220_L	236_P	0.527	0.59
87_Q	196_F	0.526	0.59
124_Y	236_P	0.524	0.58
99_G	198_Q	0.523	0.58
140_S	225_W	0.523	0.58
124_Y	128_A	0.522	0.58
72_I	166_T	0.521	0.58
26_G	38_L	0.521	0.58
95_H	198_Q	0.520	0.58
95_H	196_F	0.518	0.58
211_G	232_P	0.518	0.58
122_R	248_T	0.518	0.58
131_I	161_V	0.517	0.57
154_H	225_W	0.517	0.57
46_I	112_W	0.517	0.57
94_S	121_E	0.514	0.57
144_A	181_I	0.514	0.57
137_R	208_Y	0.510	0.56
128_A	149_H	0.510	0.56
87_Q	199_S	0.509	0.56
162_E	193_P	0.506	0.56
187_R	251_M	0.506	0.56
58_Q	153_V	0.505	0.56
172_A	213_I	0.505	0.56
39_V	42_R	0.505	0.56
116_C	124_Y	0.503	0.55
131_I	160_F	0.502	0.55
87_Q	114_M	0.502	0.55
233_L	242_R	0.502	0.55
146_H	215_I	0.501	0.55
153_V	235_P	0.501	0.55
126_Q	240_V	0.500	0.55
87_Q	124_Y	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1vk6A	2	0.9961	100	0.364	Contact Map
3cngA	4	0.6304	100	0.688	Contact Map
2qjtB	2	0.9611	100	0.702	Contact Map
2a6tA	1	0.7549	99.9	0.739	Contact Map
3q1pA	2	0.6848	99.9	0.747	Contact Map
4hfqA	2	0.7004	99.9	0.757	Contact Map
2qjoA	3	0.9533	99.9	0.763	Contact Map
2b0vA	2	0.5136	99.8	0.774	Contact Map
3fjyA	2	0.5409	99.8	0.786	Contact Map
3gz5A	2	0.5058	99.8	0.786	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0085 seconds.