GREMLIN Database
FDOG - Formate dehydrogenase-O major subunit
UniProt: P32176 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11858
Length: 1016 (916)
Sequences: 1207 (529)
Seq/√Len: 17.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
289_L293_N7.2881.00
659_R662_K5.4541.00
311_I341_E5.4161.00
554_C589_T5.2211.00
228_V265_T4.7791.00
291_L428_I4.2471.00
314_E341_E4.1581.00
643_P646_A4.0801.00
315_D321_G4.0741.00
363_L847_F3.8801.00
793_D796_R3.7311.00
638_K641_D3.6981.00
813_D850_H3.6231.00
374_D384_K3.5661.00
550_N577_K3.5461.00
573_L579_L3.5181.00
376_V387_F3.4451.00
397_T404_A3.3670.99
930_K960_T3.2790.99
625_S628_N3.2580.99
334_D338_W3.2280.99
372_T375_V3.2050.99
257_V266_A3.1720.99
933_I952_A3.1370.99
308_A431_L3.0570.99
330_K334_D3.0280.99
329_E334_D3.0110.99
891_Y931_L3.0070.99
312_V363_L2.9990.99
522_S526_D2.9950.99
870_N876_F2.9270.99
329_E338_W2.9150.98
314_E356_H2.9080.98
870_N877_K2.8820.98
314_E358_R2.8650.98
297_F361_W2.8630.98
292_L361_W2.8070.98
285_S368_V2.7860.98
831_E835_R2.7690.98
330_K338_W2.7560.98
403_T437_M2.7330.98
254_K389_K2.7210.98
287_V391_C2.6790.97
277_S970_T2.6760.97
348_A352_T2.6750.97
394_I404_A2.6670.97
341_E356_H2.6300.97
283_F390_V2.5940.97
870_N873_A2.5940.97
247_A253_A2.5840.97
110_F123_Q2.5330.96
877_K880_A2.4980.96
477_D480_T2.4500.95
387_F391_C2.4210.95
335_K338_W2.4200.95
124_I129_A2.4070.95
333_Y338_W2.3760.95
871_P877_K2.3630.94
60_L74_S2.3610.94
871_P876_F2.3530.94
727_L735_C2.3430.94
349_K352_T2.3250.94
750_Q753_R2.3180.94
295_E299_R2.2980.94
925_E956_K2.2740.93
377_E384_K2.2640.93
244_A255_L2.2630.93
273_A382_T2.2430.93
306_T430_L2.2430.93
657_F661_R2.2410.93
326_Y331_R2.2230.92
786_D790_N2.2220.92
343_D348_A2.2020.92
299_R303_E2.1910.92
661_R676_L2.1820.92
348_A351_D2.1630.91
334_D337_S2.1590.91
305_Y787_P2.1540.91
225_L396_E2.1360.91
586_N591_N2.1160.90
331_R334_D2.1110.90
417_V421_N2.1020.90
766_L770_W2.0970.90
184_L723_S2.0920.90
847_F854_F2.0800.89
849_E864_H2.0740.89
272_Y382_T2.0710.89
497_Y504_F2.0650.89
702_L734_S2.0550.89
343_D346_G2.0530.89
302_T431_L2.0490.89
305_Y825_P2.0450.89
678_M714_I2.0390.88
871_P874_R2.0390.88
870_N880_A2.0340.88
227_V406_F2.0300.88
896_Y972_G2.0120.88
331_R338_W1.9880.87
131_D659_R1.9750.87
735_C741_A1.9560.86
341_E358_R1.9470.86
722_S726_Q1.9440.86
254_K393_Y1.9300.86
329_E337_S1.9290.85
870_N879_D1.9230.85
679_T682_Y1.9210.85
871_P880_A1.9210.85
228_V255_L1.9170.85
720_Q734_S1.9090.85
317_G324_T1.9060.85
285_S371_Y1.9030.85
386_A389_K1.8960.84
516_K519_A1.8870.84
330_K337_S1.8860.84
723_S741_A1.8740.84
228_V244_A1.8680.84
350_R491_L1.8630.83
695_M700_K1.8580.83
817_A820_G1.8360.82
412_W425_M1.8340.82
396_E402_K1.8330.82
979_Y982_V1.8320.82
273_A386_A1.8290.82
508_M512_F1.8240.82
343_D352_T1.8230.82
669_G672_P1.8200.82
790_N800_K1.8140.82
354_L361_W1.8140.82
125_S128_E1.8130.82
876_F880_A1.8110.82
406_F425_M1.8040.81
229_M284_L1.7980.81
870_N875_I1.7870.81
700_K703_A1.7820.80
172_E785_A1.7770.80
543_M548_K1.7760.80
334_D339_T1.7710.80
225_L393_Y1.7680.80
647_L655_G1.7610.80
487_P496_N1.7340.79
343_D351_D1.7140.78
271_Y389_K1.7140.78
617_T639_G1.7110.78
704_D710_T1.7110.78
679_T683_A1.7110.78
343_D349_K1.7010.77
701_A704_D1.6890.77
872_A876_F1.6860.77
288_L368_V1.6860.77
414_Q418_G1.6800.76
224_N397_T1.6790.76
383_P386_A1.6790.76
341_E349_K1.6780.76
478_L482_L1.6750.76
926_S930_K1.6720.76
279_T379_I1.6700.76
370_R849_E1.6670.76
742_G831_E1.6660.76
667_Q672_P1.6650.76
903_H975_I1.6620.75
216_H630_G1.6600.75
345_N348_A1.6600.75
669_G673_D1.6600.75
137_M553_I1.6540.75
924_G960_T1.6530.75
142_D667_Q1.6530.75
505_F509_M1.6520.75
219_D222_N1.6470.75
300_E304_A1.6460.75
482_L502_P1.6370.74
871_P875_I1.6300.74
224_N251_N1.6270.74
382_T390_V1.6250.74
334_D340_Y1.6230.74
573_L589_T1.6200.74
377_E391_C1.6200.74
584_P618_C1.6190.74
329_E332_K1.6160.73
921_V941_V1.6150.73
130_F655_G1.6080.73
273_A390_V1.6010.73
300_E303_E1.5990.73
133_I612_F1.5950.72
581_T593_W1.5930.72
302_T308_A1.5920.72
617_T642_A1.5860.72
682_Y685_P1.5840.72
257_V265_T1.5810.72
919_Q989_A1.5760.71
516_K677_N1.5730.71
332_K338_W1.5710.71
581_T590_S1.5690.71
204_L211_G1.5690.71
133_I611_V1.5650.71
689_S692_E1.5610.71
245_M248_K1.5600.71
870_N874_R1.5590.71
344_E349_K1.5540.70
528_L713_V1.5490.70
838_A844_E1.5490.70
287_V394_I1.5390.70
337_S340_Y1.5360.69
479_Q483_T1.5320.69
133_I614_L1.5260.69
315_D337_S1.5120.68
469_T501_Y1.5110.68
514_G517_A1.5080.68
377_E387_F1.5020.68
663_M667_Q1.4970.67
139_E143_A1.4960.67
926_S960_T1.4890.67
84_H222_N1.4850.67
681_N684_I1.4840.67
287_V428_I1.4830.67
228_V233_A1.4790.66
363_L366_Q1.4730.66
723_S774_L1.4720.66
873_A876_F1.4710.66
330_K339_T1.4570.65
290_Y395_A1.4510.65
858_L862_P1.4390.64
47_R58_G1.4370.64
246_E250_H1.4360.64
898_L901_H1.4350.64
871_P879_D1.4320.64
235_E264_R1.4290.64
468_M481_Y1.4250.63
311_I314_E1.4200.63
583_D587_T1.4180.63
208_F211_G1.4160.63
361_W431_L1.4160.63
274_P277_S1.4130.63
524_G677_N1.4110.63
682_Y688_P1.4080.62
322_L326_Y1.4080.62
948_I992_L1.4070.62
303_E354_L1.4040.62
633_L792_W1.4030.62
750_Q755_D1.3930.62
299_R361_W1.3880.61
296_K392_E1.3790.61
247_A251_N1.3790.61
519_A523_W1.3620.60
701_A709_A1.3620.60
518_T521_N1.3620.60
502_P729_D1.3590.60
571_G575_K1.3580.60
311_I349_K1.3580.60
329_E335_K1.3560.59
537_V563_F1.3520.59
897_R903_H1.3490.59
124_I128_E1.3380.58
113_Y124_I1.3380.58
735_C772_W1.3280.58
804_T810_D1.3260.58
309_S354_L1.3250.58
130_F656_I1.3240.58
739_I771_A1.3240.58
876_F879_D1.3230.58
719_Q746_P1.3190.57
223_A226_V1.3180.57
891_Y930_K1.3170.57
873_A877_K1.3120.57
475_Q484_A1.3100.57
335_K339_T1.3060.56
102_I640_A1.3050.56
361_W805_K1.3040.56
275_I382_T1.3040.56
486_T502_P1.2990.56
384_K388_L1.2980.56
312_V837_F1.2930.56
133_I580_V1.2840.55
283_F380_C1.2830.55
287_V292_L1.2820.55
683_A687_E1.2810.55
289_L369_S1.2800.55
437_M793_D1.2780.55
506_V530_K1.2780.55
514_G521_N1.2780.55
228_V257_V1.2730.55
430_L863_L1.2650.54
449_S897_R1.2600.54
979_Y983_A1.2580.54
545_K571_G1.2550.53
500_N503_K1.2510.53
564_P1006_F1.2500.53
389_K393_Y1.2460.53
282_A286_G1.2450.53
330_K335_K1.2430.53
815_S823_V1.2430.53
560_V570_I1.2400.53
582_I616_S1.2390.52
408_Y425_M1.2390.52
862_P865_P1.2360.52
776_R780_Y1.2340.52
722_S725_A1.2280.52
329_E339_T1.2260.52
451_I454_L1.2260.52
403_T793_D1.2250.52
311_I356_H1.2250.52
589_T887_D1.2250.52
292_L369_S1.2230.51
414_Q421_N1.2220.51
764_N798_L1.2210.51
660_L723_S1.2200.51
161_T187_L1.2190.51
190_D195_V1.2190.51
696_E699_G1.2140.51
587_T971_I1.2120.51
538_L1004_P1.2110.51
310_L833_M1.2100.51
204_L210_R1.2050.50
286_G376_V1.2030.50
930_K969_D1.2030.50
921_V950_A1.2020.50
923_I952_A1.2020.50
695_M701_A1.1920.50
495_V816_A1.1880.49
757_A761_G1.1880.49
750_Q754_R1.1870.49
506_V514_G1.1830.49
421_N1008_S1.1790.49
337_S837_F1.1790.49
375_V378_N1.1790.49
485_N501_Y1.1760.49
497_Y721_L1.1750.49
313_R341_E1.1750.49
217_W629_S1.1730.48
911_L914_I1.1690.48
138_K667_Q1.1670.48
412_W418_G1.1640.48
815_S818_P1.1640.48
480_T543_M1.1620.48
167_S190_D1.1600.48
682_Y687_E1.1600.48
460_L781_N1.1590.48
203_S923_I1.1550.47
209_G212_A1.1540.47
686_H712_A1.1540.47
524_G671_N1.1530.47
405_S443_N1.1500.47
511_A736_G1.1490.47
274_P388_L1.1480.47
753_R757_A1.1470.47
700_K720_Q1.1470.47
389_K392_E1.1470.47
517_A521_N1.1450.47
296_K399_A1.1430.47
898_L974_P1.1390.46
923_I933_I1.1380.46
745_T750_Q1.1350.46
333_Y337_S1.1340.46
204_L209_G1.1330.46
308_A361_W1.1330.46
751_M755_D1.1330.46
938_T951_K1.1320.46
53_C57_C1.1320.46
872_A875_I1.1310.46
281_I417_V1.1310.46
227_V258_I1.1310.46
257_V263_T1.1300.46
586_N613_R1.1230.45
751_M754_R1.1230.45
755_D767_G1.1230.45
172_E782_R1.1230.45
225_L404_A1.1220.45
175_Y179_K1.1200.45
958_I972_G1.1170.45
743_S751_M1.1150.45
670_A721_L1.1120.45
295_E399_A1.1070.44
229_M428_I1.1050.44
332_K337_S1.1040.44
228_V263_T1.1040.44
553_I580_V1.1020.44
797_Q800_K1.1000.44
282_A379_I1.0950.44
497_Y886_A1.0880.43
670_A673_D1.0870.43
297_F507_S1.0870.43
881_E885_K1.0870.43
648_T651_E1.0860.43
373_P387_F1.0810.43
705_I708_P1.0800.43
572_C778_I1.0780.43
875_I880_A1.0750.43
224_N403_T1.0750.43
475_Q485_N1.0730.42
924_G969_D1.0730.42
361_W368_V1.0720.42
554_C579_L1.0700.42
137_M180_F1.0690.42
856_T859_G1.0690.42
313_R337_S1.0680.42
478_L506_V1.0660.42
509_M523_W1.0650.42
256_I271_Y1.0600.42
271_Y390_V1.0580.42
329_E971_I1.0580.42
897_R975_I1.0580.42
515_D519_A1.0560.41
291_L361_W1.0560.41
523_W528_L1.0550.41
421_N425_M1.0530.41
410_L897_R1.0500.41
388_L392_E1.0480.41
678_M682_Y1.0470.41
907_K912_N1.0440.41
449_S626_I1.0410.41
711_G714_I1.0410.41
679_T685_P1.0410.41
271_Y386_A1.0400.41
651_E655_G1.0390.40
709_A712_A1.0380.40
277_S1008_S1.0360.40
333_Y339_T1.0310.40
288_L431_L1.0310.40
687_E725_A1.0280.40
701_A717_K1.0270.40
284_L412_W1.0260.40
532_D703_A1.0250.40
852_E855_E1.0180.39
132_R136_L1.0180.39
632_W771_A1.0160.39
87_N90_A1.0130.39
798_L815_S1.0120.39
239_V626_I1.0070.39
614_L652_I1.0040.38
632_W769_A1.0040.38
671_N674_Q1.0010.38
48_N61_M1.0010.38
668_G672_P1.0000.38
479_Q554_C0.9990.38
874_R877_K0.9980.38
662_K665_A0.9980.38
545_K548_K0.9980.38
251_N397_T0.9970.38
616_S636_H0.9950.38
749_N753_R0.9940.38
364_L368_V0.9910.38
816_A819_P0.9910.38
872_A877_K0.9890.38
410_L975_I0.9890.38
59_L98_L0.9880.38
623_N636_H0.9880.38
801_W845_G0.9870.37
388_L729_D0.9860.37
333_Y340_Y0.9860.37
244_A268_V0.9840.37
825_P834_G0.9840.37
816_A820_G0.9810.37
904_Y975_I0.9810.37
162_G167_S0.9800.37
171_N453_G0.9800.37
297_F437_M0.9790.37
336_S339_T0.9780.37
829_Q835_R0.9780.37
330_K340_Y0.9700.36
907_K914_I0.9700.36
679_T688_P0.9690.36
138_K142_D0.9690.36
652_I656_I0.9680.36
309_S352_T0.9680.36
335_K340_Y0.9670.36
562_S989_A0.9640.36
552_Y559_P0.9630.36
473_E531_W0.9630.36
119_D122_Q0.9620.36
647_L651_E0.9620.36
874_R880_A0.9610.36
46_T64_L0.9610.36
758_D761_G0.9610.36
263_T266_A0.9610.36
229_M538_L0.9600.36
451_I633_L0.9560.36
442_V892_V0.9560.36
563_F975_I0.9530.36
584_P620_A0.9520.35
975_I989_A0.9520.35
458_G939_V0.9490.35
861_N865_P0.9460.35
204_L212_A0.9460.35
64_L67_G0.9450.35
547_G575_K0.9440.35
554_C645_I0.9420.35
220_I407_L0.9420.35
512_F713_V0.9410.35
709_A714_I0.9400.35
57_C92_C0.9390.35
468_M508_M0.9390.35
721_L727_L0.9370.35
700_K709_A0.9370.35
693_V700_K0.9370.35
790_N805_K0.9370.35
396_E399_A0.9330.34
449_S903_H0.9330.34
582_I652_I0.9310.34
478_L978_G0.9310.34
207_T211_G0.9300.34
620_A636_H0.9280.34
679_T687_E0.9280.34
97_G106_S0.9280.34
531_W937_D0.9280.34
861_N864_H0.9270.34
554_C656_I0.9260.34
205_A211_G0.9220.34
591_N980_E0.9220.34
853_P1008_S0.9220.34
229_M412_W0.9220.34
854_F873_A0.9200.34
540_Y552_Y0.9180.34
406_F549_V0.9160.34
172_E276_R0.9160.34
282_A287_V0.9150.33
935_Q953_V0.9140.33
451_I457_L0.9130.33
464_L468_M0.9120.33
659_R663_M0.9120.33
461_S536_D0.9110.33
706_T713_V0.9100.33
531_W573_L0.9090.33
740_F745_T0.9080.33
716_K719_Q0.9060.33
273_A283_F0.9050.33
660_L721_L0.9050.33
802_D812_P0.9030.33
494_Q696_E0.8980.33
373_P391_C0.8980.33
566_K991_T0.8970.33
685_P688_P0.8950.32
804_T850_H0.8940.32
524_G673_D0.8930.32
666_E934_A0.8900.32
921_V973_I0.8890.32
366_Q369_S0.8890.32
178_Q188_A0.8890.32
942_S947_Y0.8870.32
165_C173_T0.8870.32
651_E778_I0.8860.32
115_A118_S0.8850.32
351_D356_H0.8850.32
227_V394_I0.8830.32
516_K672_P0.8830.32
429_Q435_M0.8830.32
80_G84_H0.8830.32
501_Y854_F0.8820.32
115_A122_Q0.8810.32
573_L592_F0.8800.32
542_E549_V0.8800.32
176_L727_L0.8800.32
589_T592_F0.8800.32
53_C92_C0.8790.32
708_P711_G0.8780.31
426_A723_S0.8780.31
220_I405_S0.8780.31
392_E396_E0.8750.31
79_E86_V0.8740.31
254_K729_D0.8740.31
259_D266_A0.8720.31
888_K944_N0.8720.31
485_N496_N0.8720.31
244_A265_T0.8710.31
545_K572_C0.8710.31
407_L412_W0.8700.31
542_E546_E0.8700.31
300_E625_S0.8700.31
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42_R65_G0.5580.17
559_P986_G0.5580.17
125_S300_E0.5570.17
321_G429_Q0.5570.17
47_R102_I0.5570.17
141_R773_P0.5570.17
1005_E1008_S0.5560.17
210_R214_T0.5560.17
282_A377_E0.5560.17
899_T987_F0.5560.17
235_E920_F0.5560.17
61_M164_L0.5550.17
922_E957_R0.5550.17
141_R857_P0.5550.17
321_G782_R0.5550.17
467_Y972_G0.5550.17
361_W937_D0.5550.17
329_E340_Y0.5540.17
161_T178_Q0.5530.17
257_V970_T0.5530.17
789_G892_V0.5530.17
141_R276_R0.5520.17
230_G411_G0.5520.17
519_A565_N0.5510.17
552_Y576_L0.5500.17
137_M580_V0.5500.17
875_I879_D0.5490.17
414_Q559_P0.5490.17
504_F949_K0.5490.17
348_A489_P0.5490.17
410_L562_S0.5490.17
49_T173_T0.5480.17
328_A379_I0.5480.17
339_T386_A0.5470.17
566_K570_I0.5470.17
368_V495_V0.5470.17
244_A499_G0.5460.17
243_W302_T0.5460.17
235_E259_D0.5460.17
93_P96_A0.5460.17
563_F566_K0.5460.17
515_D677_N0.5450.17
668_G671_N0.5450.17
80_G264_R0.5450.17
909_A912_N0.5450.17
681_N685_P0.5440.17
215_N443_N0.5440.17
931_L971_I0.5440.17
551_G578_F0.5430.17
308_A834_G0.5430.17
292_L303_E0.5430.17
777_R780_Y0.5430.17
722_S766_L0.5420.17
760_S843_A0.5420.17
337_S590_S0.5420.17
39_K43_T0.5420.17
801_W852_E0.5410.17
495_V650_G0.5400.17
550_N983_A0.5400.17
181_S186_M0.5400.17
435_M807_T0.5390.17
541_F544_M0.5390.17
54_S199_P0.5380.17
367_H434_N0.5380.17
285_S288_L0.5370.17
206_P212_A0.5370.17
860_T868_I0.5370.17
166_A174_G0.5360.17
206_P211_G0.5360.17
210_R826_F0.5360.17
451_I627_V0.5360.17
86_V420_Q0.5350.17
236_A619_F0.5340.17
564_P783_A0.5340.17
455_T791_P0.5340.17
231_G407_L0.5330.17
784_S890_P0.5330.17
80_G89_G0.5330.17
364_L847_F0.5330.17
163_M170_S0.5330.17
227_V287_V0.5330.17
680_W683_A0.5320.17
564_P1004_P0.5320.17
163_M199_P0.5320.17
317_G337_S0.5310.17
164_L797_Q0.5310.17
333_Y467_Y0.5310.17
46_T168_A0.5310.17
276_R381_G0.5310.17
901_H905_W0.5310.17
561_A904_Y0.5300.17
464_L813_D0.5300.17
244_A960_T0.5300.17
213_M217_W0.5300.17
377_E923_I0.5290.16
536_D540_Y0.5290.16
298_N395_A0.5290.16
679_T686_H0.5280.16
273_A942_S0.5280.16
708_P712_A0.5280.16
43_T76_F0.5270.16
100_D170_S0.5270.16
199_P203_S0.5270.16
369_S396_E0.5270.16
794_P797_Q0.5270.16
55_V91_L0.5270.16
115_A120_K0.5270.16
236_A240_G0.5270.16
114_R185_G0.5260.16
826_F992_L0.5260.16
254_K648_T0.5250.16
282_A575_K0.5250.16
206_P209_G0.5250.16
379_I921_V0.5250.16
233_A407_L0.5250.16
400_H786_D0.5250.16
738_W827_I0.5250.16
284_L425_M0.5250.16
721_L741_A0.5250.16
196_U791_P0.5250.16
292_L364_L0.5250.16
496_N743_S0.5250.16
517_A523_W0.5250.16
281_I982_V0.5240.16
289_L660_L0.5240.16
229_M583_D0.5240.16
458_G472_S0.5240.16
503_K729_D0.5240.16
264_R427_M0.5230.16
618_C646_A0.5230.16
566_K975_I0.5230.16
838_A886_A0.5220.16
442_V822_G0.5220.16
251_N929_N0.5220.16
457_L697_S0.5220.16
188_A451_I0.5210.16
106_S109_K0.5210.16
335_K346_G0.5200.16
362_N369_S0.5200.16
392_E929_N0.5200.16
540_Y584_P0.5190.16
309_S473_E0.5190.16
486_T501_Y0.5190.16
628_N632_W0.5190.16
59_L99_V0.5180.16
40_L43_T0.5180.16
333_Y353_T0.5180.16
182_R188_A0.5180.16
128_E952_A0.5170.16
318_F849_E0.5170.16
81_D836_L0.5170.16
665_A681_N0.5170.16
281_I901_H0.5160.16
51_T179_K0.5160.16
129_A269_A0.5160.16
296_K729_D0.5160.16
251_N524_G0.5160.16
754_R757_A0.5160.16
254_K270_D0.5150.16
218_V765_T0.5150.16
438_A796_R0.5150.16
47_R100_D0.5150.16
240_G902_F0.5150.16
502_P937_D0.5140.16
649_D903_H0.5140.16
514_G680_W0.5130.16
92_C114_R0.5130.16
285_S969_D0.5130.16
646_A863_L0.5130.16
228_V235_E0.5120.16
87_N112_E0.5120.16
182_R276_R0.5120.16
931_L939_V0.5110.16
510_K782_R0.5110.16
689_S693_V0.5110.16
495_V499_G0.5110.16
449_S652_I0.5110.16
371_Y424_T0.5110.16
410_L555_Q0.5110.16
39_K58_G0.5110.16
412_W422_I0.5110.16
574_S659_R0.5110.16
64_L100_D0.5100.16
204_L208_F0.5100.16
292_L889_F0.5100.16
575_K860_T0.5090.16
468_M733_T0.5090.16
541_F559_P0.5080.16
53_C95_G0.5080.16
252_G566_K0.5080.16
427_M442_V0.5080.16
347_F837_F0.5070.16
798_L816_A0.5070.16
394_I406_F0.5070.16
404_A428_I0.5070.16
345_N351_D0.5070.16
51_T101_F0.5070.16
832_G890_P0.5070.16
695_M702_L0.5060.16
173_T177_T0.5060.16
460_L780_Y0.5060.16
75_I103_H0.5050.16
385_D665_A0.5050.16
532_D939_V0.5050.16
191_N195_V0.5050.16
568_K879_D0.5050.16
122_Q262_F0.5050.16
253_A635_W0.5040.16
801_W810_D0.5040.16
167_S198_G0.5040.16
458_G739_I0.5030.16
52_Y78_I0.5030.16
632_W1004_P0.5030.16
571_G995_F0.5030.16
256_I390_V0.5020.16
223_A633_L0.5020.16
235_E265_T0.5020.16
310_L959_R0.5020.16
109_K123_Q0.5020.16
291_L622_E0.5020.16
89_G107_R0.5020.16
331_R335_K0.5020.16
167_S195_V0.5020.16
567_N743_S0.5020.16
516_K717_K0.5010.16
637_W752_A0.5010.16
656_I703_A0.5010.16
448_H903_H0.5010.16
538_L656_I0.5010.16
485_N854_F0.5000.16
695_M734_S0.5000.16
727_L758_D0.5000.16
47_R199_P0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1kqfA 3 0.9587 100 0.404 Contact Map
1h0hA 1 0.9449 100 0.436 Contact Map
1q16A 2 0.9459 100 0.472 Contact Map
2ivfA 1 0.8091 100 0.579 Contact Map
3ml1A 1 0.7687 100 0.639 Contact Map
2iv2X 1 0.6496 100 0.653 Contact Map
2vpzA 1 0.6831 100 0.657 Contact Map
2napA 1 0.7008 100 0.661 Contact Map
2e7zA 1 0.6841 100 0.671 Contact Map
4aayA 6 0.6978 100 0.675 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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