RHAB - ECOLI - GREMLIN Contacts

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RHAB - L-Rhamnulokinase

UniProt:	P32171	Sequences: MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLMPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQEQQINDLPALISATQALPACRFIINPNDDRFINPETMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11868
Length:	489 (466)
Sequences:	12522 (8540)
Seq/√Len:	395.6

ECOLI - RHAB LYXK XYLB ARAB LSRK GLPK FUCK YGCE
BACSU - XYLB GNTK ARAB GLPK RHAB YOAC
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
194_E	204_K	4.280	1.00
110_L	145_E	3.851	1.00
22_R	26_E	3.620	1.00
18_V	63_G	3.392	1.00
113_Q	145_E	3.355	1.00
380_A	384_H	2.866	1.00
186_N	189_S	2.841	1.00
380_A	475_V	2.833	1.00
126_R	193_D	2.829	1.00
387_A	419_I	2.803	1.00
96_V	150_L	2.785	1.00
411_Q	415_D	2.760	1.00
355_E	367_L	2.742	1.00
325_L	366_E	2.717	1.00
185_V	210_P	2.701	1.00
171_K	209_R	2.675	1.00
396_Q	422_I	2.662	1.00
445_N	449_D	2.619	1.00
20_L	67_V	2.575	1.00
42_L	98_L	2.554	1.00
446_N	449_D	2.545	1.00
97_G	147_Q	2.529	1.00
212_H	215_N	2.513	1.00
57_E	167_R	2.509	1.00
91_Q	155_A	2.454	1.00
54_D	167_R	2.431	1.00
90_D	153_H	2.431	1.00
191_D	204_K	2.365	1.00
197_L	204_K	2.348	1.00
186_N	193_D	2.322	1.00
314_D	317_A	2.286	1.00
420_R	462_T	2.225	1.00
380_A	472_A	2.220	1.00
37_R	62_L	2.192	1.00
37_R	66_K	2.169	1.00
194_E	198_A	2.165	1.00
19_M	430_T	2.143	1.00
9_V	60_I	2.130	1.00
235_S	240_S	2.115	1.00
165_S	234_A	2.111	1.00
156_H	172_M	2.069	1.00
302_L	371_I	2.067	1.00
54_D	94_Q	2.013	1.00
113_Q	117_Q	2.005	1.00
464_T	467_P	2.002	1.00
363_S	366_E	1.987	1.00
169_T	230_V	1.977	1.00
330_F	366_E	1.967	1.00
45_Q	48_Y	1.956	1.00
7_V	64_L	1.951	1.00
122_D	125_Q	1.945	1.00
418_G	468_D	1.943	1.00
387_A	393_D	1.902	1.00
66_K	70_E	1.898	1.00
261_S	299_G	1.898	1.00
221_I	224_Q	1.889	1.00
324_A	365_A	1.886	1.00
399_I	410_N	1.885	1.00
6_C	438_L	1.880	1.00
317_A	320_S	1.845	1.00
7_V	18_V	1.843	1.00
11_L	16_G	1.840	1.00
141_R	145_E	1.835	1.00
475_V	479_H	1.810	1.00
211_T	215_N	1.793	1.00
306_V	371_I	1.792	1.00
5_N	20_L	1.777	1.00
415_D	467_P	1.747	1.00
122_D	126_R	1.746	1.00
126_R	195_S	1.737	1.00
173_N	211_T	1.730	1.00
93_G	166_Y	1.727	1.00
122_D	195_S	1.712	1.00
216_V	231_V	1.709	1.00
35_I	66_K	1.706	1.00
90_D	94_Q	1.695	1.00
88_L	143_L	1.695	1.00
112_A	116_Q	1.678	1.00
40_N	55_S	1.666	1.00
231_V	440_T	1.660	1.00
222_C	226_N	1.659	1.00
115_Q	120_K	1.658	1.00
252_A	396_Q	1.658	1.00
407_T	461_T	1.653	1.00
216_V	219_H	1.628	1.00
304_Q	308_Q	1.604	1.00
109_G	113_Q	1.601	1.00
15_S	36_H	1.598	1.00
321_A	365_A	1.588	1.00
6_C	443_E	1.577	1.00
88_L	206_W	1.567	1.00
321_A	324_A	1.566	1.00
87_V	160_M	1.564	1.00
188_N	270_P	1.557	1.00
33_R	70_E	1.555	1.00
352_A	359_P	1.553	1.00
468_D	472_A	1.551	1.00
219_H	227_E	1.546	1.00
121_R	125_Q	1.526	1.00
68_C	71_G	1.494	1.00
384_H	387_A	1.491	1.00
149_E	152_P	1.485	1.00
268_Q	288_E	1.471	1.00
52_D	55_S	1.468	1.00
320_S	324_A	1.461	1.00
23_Y	443_E	1.458	1.00
165_S	217_I	1.456	1.00
384_H	479_H	1.443	1.00
216_V	229_P	1.426	1.00
54_D	58_S	1.416	1.00
322_T	408_L	1.415	1.00
438_L	444_L	1.403	1.00
318_L	368_A	1.403	1.00
203_N	206_W	1.402	1.00
369_R	373_D	1.400	1.00
407_T	423_A	1.399	1.00
57_E	61_R	1.393	1.00
469_S	472_A	1.366	1.00
418_G	472_A	1.358	1.00
250_S	268_Q	1.355	1.00
319_I	323_Q	1.352	1.00
76_S	437_Q	1.347	1.00
163_Y	167_R	1.344	1.00
122_D	199_W	1.344	1.00
142_A	146_Q	1.341	1.00
408_L	412_L	1.340	1.00
89_L	158_L	1.338	1.00
321_A	364_D	1.334	1.00
9_V	64_L	1.329	1.00
257_S	413_C	1.327	1.00
377_L	474_Y	1.318	1.00
396_Q	420_R	1.312	1.00
176_Y	190_D	1.312	1.00
376_A	412_L	1.311	1.00
108_N	112_A	1.305	1.00
253_A	394_F	1.302	1.00
332_I	477_Q	1.296	1.00
169_T	218_G	1.295	1.00
83_G	236_H	1.294	1.00
110_L	141_R	1.291	1.00
197_L	207_F	1.287	1.00
376_A	416_A	1.278	1.00
16_G	60_I	1.276	1.00
358_Q	362_E	1.265	1.00
249_G	451_R	1.263	1.00
376_A	413_C	1.262	1.00
211_T	217_I	1.259	1.00
255_L	413_C	1.257	1.00
16_G	59_A	1.247	1.00
35_I	38_F	1.242	1.00
137_L	200_S	1.241	1.00
313_N	317_A	1.234	1.00
165_S	173_N	1.234	1.00
144_T	151_I	1.230	1.00
42_L	55_S	1.224	1.00
85_D	99_P	1.222	1.00
5_N	73_R	1.218	1.00
93_G	172_M	1.217	1.00
123_I	131_F	1.213	1.00
405_Q	426_V	1.211	1.00
171_K	211_T	1.207	1.00
235_S	436_I	1.198	1.00
249_G	252_A	1.195	1.00
415_D	464_T	1.195	1.00
195_S	198_A	1.193	1.00
58_S	62_L	1.190	1.00
319_I	407_T	1.189	1.00
147_Q	150_L	1.186	1.00
117_Q	199_W	1.186	1.00
62_L	66_K	1.178	1.00
317_A	321_A	1.176	1.00
380_A	417_C	1.175	1.00
412_L	416_A	1.174	1.00
449_D	452_Q	1.173	1.00
52_D	98_L	1.170	1.00
471_I	474_Y	1.170	1.00
356_T	481_T	1.162	1.00
334_P	339_F	1.160	1.00
381_D	479_H	1.156	1.00
9_V	18_V	1.142	1.00
50_T	98_L	1.139	1.00
328_C	331_I	1.132	1.00
35_I	67_V	1.129	1.00
173_N	217_I	1.128	1.00
60_I	164_F	1.123	1.00
53_V	87_V	1.122	1.00
331_I	334_P	1.120	1.00
319_I	406_N	1.118	1.00
310_Q	367_L	1.114	1.00
320_S	323_Q	1.114	1.00
125_Q	272_T	1.114	1.00
109_G	112_A	1.112	1.00
158_L	172_M	1.110	1.00
149_E	153_H	1.108	1.00
316_P	319_I	1.106	1.00
420_R	464_T	1.103	1.00
88_L	154_I	1.100	1.00
353_C	358_Q	1.098	1.00
151_I	154_I	1.095	1.00
398_H	422_I	1.093	1.00
176_Y	185_V	1.093	1.00
176_Y	210_P	1.092	1.00
216_V	440_T	1.091	1.00
97_G	150_L	1.080	1.00
249_G	448_D	1.080	1.00
21_A	434_I	1.074	1.00
219_H	229_P	1.072	1.00
252_A	398_H	1.071	1.00
477_Q	480_S	1.070	1.00
111_M	131_F	1.069	1.00
6_C	441_L	1.060	1.00
88_L	140_L	1.060	1.00
435_G	450_F	1.059	1.00
77_I	228_I	1.058	1.00
56_L	160_M	1.058	1.00
79_I	165_S	1.055	1.00
384_H	475_V	1.053	1.00
112_A	115_Q	1.049	1.00
76_S	441_L	1.049	1.00
251_R	395_S	1.046	1.00
321_A	368_A	1.044	1.00
154_I	206_W	1.043	1.00
197_L	202_A	1.035	1.00
76_S	231_V	1.033	1.00
110_L	146_Q	1.031	1.00
334_P	355_E	1.030	1.00
253_A	265_F	1.027	1.00
375_L	403_G	1.026	1.00
232_A	235_S	1.026	1.00
106_R	142_A	1.022	1.00
211_T	232_A	1.019	1.00
362_E	366_E	1.016	1.00
377_L	416_A	1.015	1.00
5_N	32_L	1.015	1.00
61_R	65_N	1.007	1.00
383_L	417_C	1.006	1.00
439_M	450_F	1.005	1.00
60_I	64_L	0.998	1.00
140_L	157_A	0.998	1.00
75_D	441_L	0.997	1.00
18_V	67_V	0.996	1.00
296_N	378_L	0.996	1.00
32_L	35_I	0.993	1.00
166_Y	172_M	0.993	1.00
220_W	228_I	0.993	1.00
110_L	113_Q	0.992	1.00
125_Q	188_N	0.988	1.00
49_V	103_R	0.985	1.00
65_N	69_E	0.984	1.00
6_C	76_S	0.984	1.00
369_R	408_L	0.983	1.00
380_A	416_A	0.983	1.00
55_S	58_S	0.981	1.00
41_G	51_W	0.978	1.00
94_Q	167_R	0.977	1.00
467_P	471_I	0.976	1.00
66_K	69_E	0.974	1.00
123_I	183_Q	0.974	1.00
113_Q	116_Q	0.971	1.00
438_L	443_E	0.971	1.00
249_G	395_S	0.969	1.00
461_T	465_P	0.965	1.00
137_L	183_Q	0.962	1.00
21_A	431_L	0.960	1.00
7_V	20_L	0.959	1.00
74_I	228_I	0.953	1.00
254_Y	400_V	0.949	1.00
323_Q	408_L	0.948	1.00
80_D	429_S	0.946	1.00
263_M	383_L	0.944	1.00
20_L	74_I	0.943	1.00
88_L	157_A	0.943	1.00
472_A	476_A	0.942	1.00
231_V	441_L	0.942	1.00
403_G	409_L	0.938	1.00
150_L	153_H	0.935	1.00
464_T	468_D	0.933	1.00
143_L	150_L	0.932	1.00
154_I	157_A	0.922	1.00
148_P	152_P	0.922	1.00
284_E	289_G	0.921	1.00
174_W	179_A	0.915	1.00
68_C	74_I	0.914	1.00
315_L	318_L	0.913	1.00
119_G	199_W	0.913	1.00
410_N	461_T	0.910	1.00
35_I	63_G	0.909	1.00
190_D	212_H	0.904	1.00
417_C	420_R	0.901	1.00
325_L	328_C	0.893	1.00
338_R	355_E	0.893	1.00
185_V	189_S	0.892	1.00
7_V	74_I	0.891	1.00
141_R	144_T	0.890	1.00
86_F	157_A	0.888	1.00
119_G	122_D	0.887	1.00
261_S	379_Y	0.886	1.00
113_Q	141_R	0.885	1.00
97_G	143_L	0.881	1.00
435_G	454_V	0.880	1.00
465_P	468_D	0.880	1.00
473_H	476_A	0.879	1.00
170_G	221_I	0.877	1.00
33_R	67_V	0.876	1.00
162_D	174_W	0.875	1.00
275_T	388_Q	0.872	1.00
79_I	164_F	0.871	1.00
188_N	272_T	0.871	1.00
397_L	417_C	0.868	1.00
355_E	371_I	0.868	1.00
191_D	209_R	0.868	1.00
155_A	205_A	0.866	1.00
328_C	373_D	0.857	1.00
109_G	146_Q	0.857	1.00
377_L	475_V	0.856	1.00
439_M	447_V	0.853	1.00
179_A	192_W	0.852	1.00
173_N	209_R	0.852	1.00
11_L	164_F	0.851	1.00
358_Q	367_L	0.850	1.00
77_I	220_W	0.850	1.00
384_H	388_Q	0.846	1.00
313_N	364_D	0.846	1.00
444_L	450_F	0.845	1.00
268_Q	290_R	0.838	1.00
176_Y	212_H	0.837	1.00
241_A	400_V	0.836	1.00
84_V	181_T	0.836	1.00
111_M	138_Y	0.836	1.00
11_L	60_I	0.835	1.00
174_W	208_G	0.834	1.00
24_E	453_V	0.832	1.00
111_M	133_P	0.829	1.00
79_I	168_L	0.826	1.00
322_T	369_R	0.825	1.00
64_L	68_C	0.825	1.00
312_I	318_L	0.824	1.00
305_R	308_Q	0.823	1.00
351_A	354_R	0.822	1.00
137_L	184_L	0.819	1.00
78_G	231_V	0.819	1.00
192_W	207_F	0.818	1.00
469_S	473_H	0.818	1.00
372_F	412_L	0.811	1.00
176_Y	284_E	0.811	1.00
424_G	456_T	0.810	1.00
89_L	93_G	0.809	1.00
222_C	227_E	0.809	1.00
265_F	386_L	0.803	1.00
463_F	467_P	0.803	1.00
238_T	262_L	0.800	1.00
307_L	315_L	0.800	1.00
76_S	229_P	0.798	1.00
383_L	387_A	0.798	1.00
328_C	332_I	0.797	1.00
105_S	132_L	0.796	1.00
439_M	446_N	0.790	1.00
450_F	454_V	0.790	1.00
39_N	59_A	0.789	1.00
316_P	320_S	0.789	1.00
75_D	443_E	0.788	1.00
159_L	182_T	0.786	1.00
404_C	426_V	0.785	1.00
22_R	25_R	0.785	1.00
376_A	409_L	0.783	1.00
115_Q	131_F	0.782	1.00
352_A	356_T	0.781	1.00
140_L	184_L	0.778	1.00
348_E	351_A	0.778	1.00
306_V	367_L	0.778	1.00
96_V	153_H	0.778	1.00
424_G	455_S	0.777	1.00
249_G	452_Q	0.773	1.00
185_V	190_D	0.773	1.00
188_N	269_T	0.772	1.00
53_V	98_L	0.771	1.00
454_V	457_T	0.771	1.00
217_I	232_A	0.771	1.00
190_D	284_E	0.768	1.00
224_Q	227_E	0.768	1.00
83_G	178_N	0.765	1.00
177_T	283_N	0.764	1.00
61_R	224_Q	0.764	1.00
399_I	413_C	0.762	1.00
311_Q	364_D	0.762	1.00
191_D	194_E	0.761	1.00
399_I	423_A	0.761	1.00
255_L	261_S	0.759	1.00
44_S	48_Y	0.759	1.00
253_A	397_L	0.756	1.00
325_L	365_A	0.755	1.00
325_L	330_F	0.754	1.00
112_A	350_Q	0.754	1.00
141_R	201_G	0.753	1.00
470_E	473_H	0.753	1.00
424_G	457_T	0.752	1.00
55_S	59_A	0.752	1.00
438_L	442_D	0.752	1.00
32_L	38_F	0.750	1.00
255_L	379_Y	0.749	1.00
219_H	226_N	0.748	1.00
126_R	186_N	0.747	1.00
385_E	388_Q	0.746	1.00
109_G	145_E	0.746	1.00
174_W	210_P	0.743	1.00
245_S	254_Y	0.742	1.00
468_D	471_I	0.739	1.00
11_L	59_A	0.739	1.00
54_D	163_Y	0.739	1.00
90_D	96_V	0.737	1.00
198_A	204_K	0.737	1.00
13_A	101_A	0.736	1.00
161_P	234_A	0.735	1.00
190_D	289_G	0.731	1.00
195_S	199_W	0.731	1.00
89_L	172_M	0.729	1.00
334_P	371_I	0.726	1.00
90_D	155_A	0.726	1.00
21_A	425_P	0.724	1.00
407_T	463_F	0.724	1.00
423_A	461_T	0.724	1.00
381_D	475_V	0.724	1.00
306_V	368_A	0.723	1.00
71_G	74_I	0.721	1.00
372_F	406_N	0.719	1.00
8_A	78_G	0.718	1.00
245_S	400_V	0.717	1.00
444_L	453_V	0.717	1.00
64_L	67_V	0.716	1.00
449_D	453_V	0.716	1.00
404_C	410_N	0.716	1.00
102_Y	260_W	0.715	1.00
241_A	429_S	0.714	1.00
88_L	96_V	0.712	1.00
325_L	329_R	0.712	1.00
322_T	368_A	0.711	1.00
91_Q	153_H	0.711	1.00
323_Q	411_Q	0.710	1.00
57_E	224_Q	0.708	1.00
165_S	169_T	0.707	1.00
476_A	479_H	0.707	1.00
463_F	468_D	0.707	1.00
198_A	203_N	0.707	1.00
177_T	235_S	0.707	1.00
326_P	329_R	0.705	1.00
473_H	477_Q	0.705	1.00
58_S	61_R	0.703	1.00
61_R	167_R	0.703	1.00
193_D	196_L	0.702	1.00
466_N	469_S	0.702	1.00
247_L	254_Y	0.701	1.00
123_I	196_L	0.700	1.00
332_I	362_E	0.700	1.00
152_P	156_H	0.697	1.00
342_P	345_M	0.693	1.00
418_G	465_P	0.692	1.00
474_Y	477_Q	0.692	1.00
163_Y	166_Y	0.689	1.00
77_I	230_V	0.687	0.99
399_I	421_V	0.687	0.99
38_F	304_Q	0.687	0.99
397_L	419_I	0.686	0.99
344_T	347_S	0.686	0.99
212_H	284_E	0.686	0.99
83_G	294_L	0.685	0.99
255_L	397_L	0.685	0.99
323_Q	407_T	0.684	0.99
304_Q	315_L	0.682	0.99
322_T	325_L	0.681	0.99
93_G	155_A	0.680	0.99
21_A	30_L	0.680	0.99
186_N	191_D	0.676	0.99
334_P	337_D	0.676	0.99
6_C	75_D	0.674	0.99
463_F	466_N	0.673	0.99
291_Y	295_K	0.673	0.99
395_S	419_I	0.670	0.99
21_A	430_T	0.670	0.99
334_P	370_C	0.670	0.99
81_T	178_N	0.669	0.99
319_I	408_L	0.669	0.99
448_D	451_R	0.666	0.99
397_L	421_V	0.666	0.99
100_V	106_R	0.663	0.99
50_T	106_R	0.663	0.99
213_P	234_A	0.662	0.99
267_S	271_F	0.662	0.99
62_L	65_N	0.661	0.99
54_D	95_R	0.659	0.99
396_Q	419_I	0.659	0.99
114_A	200_S	0.659	0.99
341_N	345_M	0.658	0.99
435_G	453_V	0.657	0.99
388_Q	479_H	0.657	0.99
299_G	375_L	0.656	0.99
237_D	259_T	0.656	0.99
60_I	63_G	0.655	0.99
450_F	453_V	0.655	0.99
87_V	99_P	0.650	0.99
89_L	156_H	0.650	0.99
229_P	441_L	0.650	0.99
32_L	37_R	0.650	0.99
34_E	38_F	0.650	0.99
465_P	469_S	0.649	0.99
219_H	222_C	0.648	0.99
380_A	479_H	0.647	0.99
303_L	319_I	0.646	0.99
118_L	196_L	0.642	0.99
184_L	207_F	0.641	0.99
327_A	470_E	0.640	0.99
140_L	206_W	0.638	0.99
319_I	322_T	0.638	0.99
141_R	151_I	0.637	0.99
127_S	196_L	0.636	0.99
144_T	201_G	0.636	0.99
246_P	451_R	0.632	0.99
162_D	172_M	0.632	0.99
462_T	465_P	0.632	0.99
346_C	381_D	0.631	0.99
89_L	166_Y	0.631	0.99
86_F	136_T	0.630	0.99
121_R	124_Y	0.629	0.99
472_A	475_V	0.628	0.99
138_Y	183_Q	0.627	0.99
36_H	39_N	0.625	0.99
89_L	163_Y	0.625	0.99
247_L	252_A	0.623	0.99
23_Y	75_D	0.623	0.99
416_A	471_I	0.623	0.99
226_N	229_P	0.621	0.99
114_A	138_Y	0.621	0.99
306_V	310_Q	0.621	0.99
470_E	474_Y	0.620	0.99
439_M	444_L	0.619	0.99
141_R	200_S	0.618	0.99
435_G	439_M	0.617	0.99
373_D	412_L	0.617	0.99
463_F	471_I	0.615	0.99
333_N	477_Q	0.613	0.99
216_V	441_L	0.613	0.99
161_P	178_N	0.613	0.99
53_V	99_P	0.613	0.99
54_D	98_L	0.613	0.99
61_R	64_L	0.611	0.99
309_E	363_S	0.611	0.99
34_E	37_R	0.610	0.99
423_A	463_F	0.609	0.99
377_L	471_I	0.608	0.99
244_A	428_A	0.606	0.99
5_N	72_I	0.606	0.99
467_P	470_E	0.606	0.99
236_H	239_A	0.605	0.99
153_H	156_H	0.604	0.99
411_Q	414_A	0.603	0.99
407_T	411_Q	0.602	0.99
151_I	155_A	0.602	0.99
81_T	160_M	0.602	0.99
177_T	213_P	0.601	0.99
346_C	479_H	0.601	0.99
406_N	409_L	0.600	0.99
54_D	57_E	0.600	0.99
261_S	413_C	0.600	0.99
131_F	183_Q	0.600	0.99
82_W	102_Y	0.598	0.99
93_G	156_H	0.596	0.99
108_N	133_P	0.594	0.99
129_I	135_N	0.593	0.99
451_R	454_V	0.593	0.99
198_A	201_G	0.590	0.98
182_T	192_W	0.589	0.98
123_I	200_S	0.589	0.98
410_N	423_A	0.589	0.98
135_N	181_T	0.587	0.98
411_Q	461_T	0.587	0.98
107_T	138_Y	0.586	0.98
295_K	298_M	0.584	0.98
238_T	256_S	0.584	0.98
315_L	319_I	0.583	0.98
83_G	181_T	0.583	0.98
328_C	369_R	0.582	0.98
333_N	355_E	0.581	0.98
412_L	467_P	0.581	0.98
319_I	372_F	0.581	0.98
6_C	444_L	0.581	0.98
94_Q	153_H	0.580	0.98
451_R	455_S	0.579	0.98
448_D	452_Q	0.579	0.98
467_P	472_A	0.579	0.98
214_G	440_T	0.578	0.98
369_R	412_L	0.578	0.98
411_Q	464_T	0.577	0.98
338_R	342_P	0.576	0.98
252_A	395_S	0.575	0.98
257_S	399_I	0.574	0.98
353_C	356_T	0.574	0.98
23_Y	438_L	0.574	0.98
334_P	374_S	0.573	0.98
327_A	331_I	0.572	0.98
263_M	382_V	0.572	0.98
209_R	215_N	0.571	0.98
50_T	97_G	0.570	0.98
255_L	263_M	0.570	0.98
87_V	95_R	0.567	0.98
48_Y	106_R	0.566	0.98
375_L	409_L	0.564	0.98
6_C	23_Y	0.564	0.98
242_V	282_T	0.563	0.98
52_D	58_S	0.563	0.98
133_P	349_I	0.562	0.98
270_P	279_A	0.558	0.98
100_V	143_L	0.557	0.98
65_N	68_C	0.555	0.98
19_M	30_L	0.555	0.98
394_F	419_I	0.553	0.98
373_D	377_L	0.553	0.98
246_P	454_V	0.553	0.98
446_N	450_F	0.551	0.98
32_L	39_N	0.551	0.98
330_F	361_P	0.551	0.98
243_I	435_G	0.551	0.98
304_Q	307_L	0.550	0.98
19_M	431_L	0.550	0.98
95_R	98_L	0.549	0.98
38_F	307_L	0.548	0.98
431_L	435_G	0.547	0.97
196_L	200_S	0.546	0.97
242_V	264_G	0.544	0.97
331_I	362_E	0.544	0.97
439_M	442_D	0.543	0.97
85_D	101_A	0.542	0.97
14_S	17_R	0.542	0.97
303_L	318_L	0.542	0.97
328_C	474_Y	0.542	0.97
158_L	166_Y	0.541	0.97
404_C	423_A	0.541	0.97
151_I	201_G	0.541	0.97
294_L	297_I	0.540	0.97
59_A	62_L	0.540	0.97
301_W	304_Q	0.539	0.97
37_R	59_A	0.539	0.97
170_G	223_P	0.539	0.97
106_R	146_Q	0.539	0.97
56_L	99_P	0.538	0.97
340_I	360_I	0.537	0.97
171_K	219_H	0.537	0.97
202_A	207_F	0.537	0.97
34_E	66_K	0.536	0.97
229_P	232_A	0.535	0.97
306_V	311_Q	0.535	0.97
413_C	417_C	0.534	0.97
414_A	421_V	0.533	0.97
212_H	287_A	0.533	0.97
327_A	369_R	0.531	0.97
221_I	227_E	0.531	0.97
43_H	49_V	0.529	0.97
395_S	420_R	0.529	0.97
159_L	178_N	0.527	0.97
213_P	235_S	0.526	0.97
412_L	471_I	0.526	0.97
88_L	97_G	0.523	0.97
48_Y	100_V	0.522	0.97
13_A	102_Y	0.522	0.97
379_Y	413_C	0.521	0.97
263_M	379_Y	0.520	0.97
183_Q	200_S	0.520	0.97
430_T	433_N	0.519	0.97
268_Q	289_G	0.519	0.97
339_F	355_E	0.519	0.97
84_V	102_Y	0.519	0.97
165_S	230_V	0.519	0.97
49_V	101_A	0.517	0.97
162_D	208_G	0.517	0.97
261_S	297_I	0.517	0.97
39_N	51_W	0.517	0.97
256_S	400_V	0.516	0.96
117_Q	141_R	0.515	0.96
35_I	70_E	0.514	0.96
177_T	239_A	0.514	0.96
38_F	41_G	0.513	0.96
259_T	301_W	0.513	0.96
5_N	22_R	0.513	0.96
267_S	293_V	0.513	0.96
84_V	260_W	0.511	0.96
176_Y	213_P	0.511	0.96
37_R	63_G	0.510	0.96
299_G	302_L	0.509	0.96
214_G	439_M	0.508	0.96
39_N	42_L	0.508	0.96
33_R	38_F	0.507	0.96
377_L	477_Q	0.507	0.96
253_A	263_M	0.507	0.96
329_R	366_E	0.506	0.96
86_F	143_L	0.504	0.96
265_F	394_F	0.503	0.96
256_S	262_L	0.503	0.96
16_G	39_N	0.502	0.96
181_T	236_H	0.502	0.96
318_L	408_L	0.501	0.96
82_W	236_H	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ll3A	2	0.9755	100	0.129	Contact Map
3ezwA	3	0.9816	100	0.149	Contact Map
2itmA	2	0.9489	100	0.15	Contact Map
3hz6A	1	0.9673	100	0.152	Contact Map
3h3nX	3	0.9796	100	0.153	Contact Map
3g25A	3	0.9796	100	0.155	Contact Map
3ifrA	2	0.9632	100	0.156	Contact Map
3wxlA	2	0.9816	100	0.157	Contact Map
2d4wA	2	0.9755	100	0.16	Contact Map
2w40A	3	0.9775	100	0.162	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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