GREMLIN Database
YIIQ - Uncharacterized protein YiiQ
UniProt: P32160 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11874
Length: 199 (181)
Sequences: 102 (64)
Seq/√Len: 4.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
65_F90_A4.6050.94
46_I108_W3.0440.70
68_I189_A2.7320.61
96_R99_L2.6950.60
87_N115_E2.4300.51
37_A82_S2.3780.50
53_F103_S2.2880.47
186_I191_S2.2030.44
99_L103_S2.1730.43
96_R147_L2.1660.43
38_G66_R2.1540.43
83_K86_E2.1400.42
90_A119_A2.1100.41
43_D171_V2.0790.40
17_V139_T2.0480.39
53_F99_L2.0270.39
26_P70_S1.9190.36
147_L159_Y1.9070.35
104_I130_V1.8450.33
62_L145_K1.8430.33
79_R187_K1.8350.33
47_S96_R1.8340.33
58_P101_I1.8320.33
129_A151_L1.8320.33
52_D183_V1.8160.33
43_D60_L1.8120.33
19_T169_Y1.7990.32
29_A160_Y1.7980.32
87_N167_L1.7580.31
45_S104_I1.6800.29
62_L153_A1.6630.29
96_R103_S1.6580.28
153_A162_E1.6430.28
52_D171_V1.6370.28
131_I137_L1.6210.27
83_K112_Q1.6040.27
150_L170_V1.5690.26
41_T128_A1.5450.26
114_P147_L1.4860.24
47_S99_L1.4830.24
53_F62_L1.4700.24
37_A163_T1.4600.24
75_A103_S1.4100.23
60_L171_V1.4090.22
46_I96_R1.3950.22
115_E191_S1.3760.22
82_S159_Y1.3730.22
87_N119_A1.3640.22
142_Q169_Y1.3100.20
173_D178_G1.3060.20
149_S172_A1.3040.20
66_R123_A1.3010.20
173_D177_K1.2930.20
21_A52_D1.2830.20
65_F119_A1.2810.20
111_I176_E1.2730.20
70_S96_R1.2440.19
96_R108_W1.2230.19
148_Q162_E1.2220.19
60_L181_F1.2070.18
62_L103_S1.1930.18
21_A189_A1.1810.18
128_A143_S1.1750.18
149_S161_T1.1600.17
98_T177_K1.1550.17
87_N111_I1.1240.17
143_S160_Y1.1210.17
46_I147_L1.1120.17
98_T173_D1.1050.16
143_S169_Y1.1040.16
125_E140_K1.0960.16
56_Q169_Y1.0920.16
17_V146_K1.0900.16
37_A131_I1.0870.16
153_A156_N1.0850.16
136_P164_E1.0840.16
181_F187_K1.0830.16
79_R181_F1.0830.16
51_E86_E1.0820.16
108_W147_L1.0760.16
38_G175_G1.0530.16
27_D53_F1.0460.15
43_D151_L1.0410.15
58_P61_P1.0390.15
45_S148_Q1.0290.15
37_A103_S1.0200.15
65_F104_I1.0150.15
35_L187_K1.0090.15
35_L79_R1.0090.15
15_L26_P1.0080.15
82_S152_T1.0070.15
92_T103_S1.0060.15
147_L161_T0.9940.15
44_L69_D0.9900.15
62_L82_S0.9880.15
31_T41_T0.9820.14
97_G100_K0.9780.14
154_G171_V0.9770.14
123_A127_M0.9710.14
137_L167_L0.9700.14
116_Q122_K0.9670.14
103_S176_E0.9620.14
12_C68_I0.9610.14
78_T177_K0.9540.14
53_F157_K0.9510.14
49_F150_L0.9380.14
41_T53_F0.9240.14
142_Q176_E0.9220.14
93_A174_N0.9110.13
52_D112_Q0.9060.13
146_K154_G0.9060.13
73_D104_I0.9050.13
46_I84_I0.9020.13
46_I176_E0.9010.13
99_L104_I0.9010.13
13_S23_A0.9000.13
18_T59_S0.8990.13
69_D75_A0.8960.13
16_T20_E0.8920.13
55_S82_S0.8850.13
60_L129_A0.8840.13
77_L177_K0.8770.13
57_N95_E0.8710.13
77_L171_V0.8650.13
164_E167_L0.8640.13
55_S145_K0.8550.13
23_A144_Q0.8520.13
67_A119_A0.8480.12
75_A169_Y0.8370.12
39_A57_N0.8350.12
108_W122_K0.8330.12
90_A113_G0.8280.12
32_A177_K0.8280.12
45_S145_K0.8260.12
33_P92_T0.8250.12
45_S157_K0.8210.12
172_A186_I0.8200.12
95_E101_I0.8190.12
62_L147_L0.8190.12
86_E113_G0.8150.12
70_S183_V0.8150.12
52_D167_L0.8130.12
86_E117_K0.8110.12
145_K172_A0.8100.12
13_S20_E0.8090.12
21_A29_A0.8080.12
73_D155_K0.8040.12
24_Q69_D0.8040.12
87_N169_Y0.8030.12
32_A178_G0.7990.12
41_T77_L0.7990.12
87_N109_L0.7970.12
68_I86_E0.7950.12
125_E146_K0.7870.12
15_L157_K0.7860.12
53_F96_R0.7840.12
62_L124_Q0.7840.12
22_H28_T0.7750.11
77_L154_G0.7730.11
26_P30_T0.7730.11
65_F167_L0.7660.11
15_L115_E0.7610.11
88_L177_K0.7580.11
36_L170_V0.7580.11
135_T183_V0.7540.11
21_A164_E0.7520.11
22_H29_A0.7500.11
128_A162_E0.7490.11
83_K132_R0.7480.11
19_T22_H0.7460.11
54_N165_G0.7460.11
72_P116_Q0.7430.11
38_G189_A0.7410.11
115_E181_F0.7390.11
96_R124_Q0.7390.11
53_F104_I0.7380.11
32_A155_K0.7370.11
119_A167_L0.7360.11
149_S158_R0.7340.11
71_S167_L0.7290.11
113_G119_A0.7280.11
55_S117_K0.7270.11
95_E102_K0.7240.11
47_S103_S0.7200.11
88_L190_L0.7160.11
22_H26_P0.7160.11
43_D129_A0.7070.11
120_K148_Q0.7050.11
83_K113_G0.7020.11
56_Q141_T0.7000.11
98_T106_M0.6970.11
38_G127_M0.6960.11
23_A75_A0.6940.10
135_T151_L0.6900.10
47_S65_F0.6890.10
47_S124_Q0.6890.10
146_K170_V0.6890.10
62_L144_Q0.6830.10
72_P104_I0.6800.10
19_T158_R0.6800.10
100_K166_A0.6770.10
53_F147_L0.6730.10
12_C112_Q0.6730.10
27_D167_L0.6710.10
129_A136_P0.6670.10
12_C17_V0.6660.10
142_Q167_L0.6660.10
59_S192_E0.6570.10
12_C138_M0.6510.10
41_T115_E0.6490.10
39_A146_K0.6470.10
32_A173_D0.6450.10
148_Q153_A0.6400.10
12_C115_E0.6320.10
115_E143_S0.6310.10
63_N147_L0.6300.10
92_T99_L0.6280.10
47_S53_F0.6270.10
23_A27_D0.6230.10
110_P149_S0.6220.10
15_L18_T0.6200.10
32_A127_M0.6200.10
51_E113_G0.6190.10
116_Q147_L0.6180.10
70_S174_N0.6170.10
78_T132_R0.6170.10
77_L88_L0.6100.10
56_Q68_I0.6020.09
86_E109_L0.6010.09
100_K169_Y0.6010.09
37_A174_N0.6010.09
20_E24_Q0.5990.09
60_L186_I0.5980.09
18_T61_P0.5960.09
67_A174_N0.5950.09
13_S17_V0.5910.09
46_I124_Q0.5890.09
93_A175_G0.5870.09
79_R106_M0.5860.09
106_M187_K0.5860.09
71_S83_K0.5810.09
133_T164_E0.5810.09
45_S99_L0.5780.09
82_S160_Y0.5760.09
57_N166_A0.5720.09
81_A110_P0.5710.09
139_T146_K0.5650.09
38_G90_A0.5650.09
32_A77_L0.5640.09
90_A174_N0.5630.09
22_H141_T0.5570.09
18_T25_T0.5530.09
67_A113_G0.5450.09
131_I147_L0.5430.09
19_T174_N0.5430.09
117_K167_L0.5370.09
85_N115_E0.5360.09
92_T164_E0.5350.09
37_A75_A0.5330.09
59_S62_L0.5280.09
49_F170_V0.5260.09
23_A71_S0.5240.09
116_Q179_L0.5230.09
14_A41_T0.5230.09
128_A153_A0.5120.09
127_M132_R0.5090.08
108_W145_K0.5080.08
93_A113_G0.5070.08
30_T39_A0.5040.08
83_K87_N0.5030.08
127_M175_G0.5030.08
106_M112_Q0.5000.08
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2do7A 1 0.3568 33.2 0.965 Contact Map
2dk8A 1 0.392 6.4 0.975 Contact Map
2jnaA 2 0.4824 6 0.975 Contact Map
4l4qA 3 0.3367 4.3 0.977 Contact Map
1w7fA 1 0.4724 4.1 0.977 Contact Map
1zchA 2 0.3668 3.9 0.977 Contact Map
1mszA 1 0.2814 3.9 0.977 Contact Map
1nf1A 1 0.3719 3.4 0.978 Contact Map
2apnA 1 0.3216 3.2 0.978 Contact Map
1x48A 1 0.4422 2.7 0.979 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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