PTFLB - ECOLI - GREMLIN Contacts

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PTFLB - Fructose-like PTS system EIIBC component

UniProt:	P32154	Sequences: MESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQGSSGVENRLSSEEIAAADYVILATGRGLSGDDRARFAGKKVYEIAISQALKNIDQIFSELPTNSQLFAADSGVKLGKQEVQSGSVMSHLMAGVSAALPFVIGGGILVALANMLVQFGLPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLANDKALLGTQSGAGFLGAVVLGLAIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVLTYYVIGPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSLLEKHIYDWYAIVGVVALMPPVAAGLATFIAPKLFTRQEKEAASSAIVVGATVATEPAIPYALAAPLPMITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVGSFYLVLAIGLALNISFIIVLKGLWLRRKAKAAQQELVHEH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11863
Length:	483 (450)
Sequences:	1491 (789)
Seq/√Len:	37.2

ECOLI - PTFLB HRSA PTFBC PTFC1 PTFC2
BACSU - PTF3A PTN3B

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
8_V	63_V	5.551	1.00
356_A	456_N	5.207	1.00
360_A	368_F	4.231	1.00
212_V	236_L	4.068	1.00
34_L	101_S	4.012	1.00
48_V	51_R	3.941	1.00
95_N	98_Q	3.799	1.00
361_T	376_A	3.797	1.00
348_V	449_L	3.782	1.00
201_A	205_A	3.768	1.00
189_I	233_A	3.737	1.00
55_E	59_A	3.725	1.00
9_A	40_V	3.693	1.00
34_L	97_D	3.646	1.00
62_Y	103_L	3.630	1.00
362_F	380_I	3.624	1.00
6_R	59_A	3.618	1.00
193_G	236_L	3.578	1.00
317_F	323_I	3.362	1.00
243_F	272_V	3.326	1.00
97_D	101_S	3.292	1.00
31_A	38_I	3.252	1.00
39_K	56_E	3.218	1.00
423_K	440_S	3.174	1.00
131_H	199_S	3.103	1.00
317_F	407_T	3.014	1.00
33_S	97_D	2.986	1.00
313_A	407_T	2.975	1.00
54_S	58_A	2.914	1.00
101_S	105_T	2.821	1.00
408_L	459_F	2.788	1.00
91_Q	95_N	2.665	1.00
142_F	210_F	2.641	1.00
187_F	214_Y	2.552	1.00
30_K	33_S	2.468	1.00
398_A	401_P	2.415	1.00
444_S	447_L	2.391	1.00
28_E	32_R	2.338	1.00
364_A	461_I	2.308	1.00
6_R	61_D	2.239	0.99
416_L	420_F	2.224	0.99
27_L	38_I	2.199	0.99
316_A	410_G	2.114	0.99
80_A	111_A	2.053	0.99
153_A	178_E	2.047	0.99
357_A	460_I	2.028	0.99
412_I	455_L	1.995	0.99
451_I	455_L	1.986	0.98
329_F	332_F	1.971	0.98
244_V	269_T	1.967	0.98
36_H	100_F	1.958	0.98
39_K	50_N	1.932	0.98
368_F	461_I	1.907	0.98
138_A	195_Y	1.898	0.98
331_C	346_V	1.898	0.98
245_F	249_K	1.894	0.98
348_V	413_T	1.883	0.98
138_A	206_F	1.875	0.98
25_E	28_E	1.862	0.98
195_Y	198_S	1.849	0.98
366_K	466_L	1.843	0.98
6_R	37_T	1.834	0.97
184_G	211_L	1.824	0.97
80_A	112_A	1.810	0.97
313_A	317_F	1.793	0.97
447_L	451_I	1.767	0.97
102_E	106_N	1.767	0.97
268_V	272_V	1.765	0.97
30_K	34_L	1.741	0.96
355_V	453_L	1.726	0.96
288_L	291_G	1.723	0.96
311_V	346_V	1.701	0.96
178_E	182_Y	1.675	0.96
52_L	57_I	1.672	0.96
8_V	52_L	1.649	0.95
175_W	179_S	1.641	0.95
207_A	270_L	1.639	0.95
186_T	214_Y	1.615	0.95
420_F	444_S	1.604	0.94
340_Y	425_L	1.588	0.94
150_V	185_F	1.577	0.94
316_A	353_P	1.573	0.94
319_M	388_T	1.559	0.94
374_E	377_S	1.559	0.94
134_A	198_S	1.526	0.93
408_L	451_I	1.517	0.93
194_A	210_F	1.495	0.92
422_I	444_S	1.492	0.92
309_F	415_V	1.481	0.92
62_Y	85_Y	1.470	0.91
197_A	240_I	1.440	0.90
145_G	270_L	1.436	0.90
34_L	100_F	1.427	0.90
5_L	61_D	1.424	0.90
316_A	388_T	1.424	0.90
405_A	459_F	1.422	0.90
191_I	210_F	1.407	0.89
158_Q	161_L	1.405	0.89
358_G	362_F	1.393	0.89
30_K	97_D	1.387	0.89
10_I	43_Q	1.380	0.88
367_L	466_L	1.378	0.88
290_G	294_H	1.376	0.88
286_S	290_G	1.374	0.88
313_A	349_V	1.366	0.88
98_Q	102_E	1.364	0.88
402_M	460_I	1.349	0.87
358_G	380_I	1.347	0.87
235_V	239_A	1.347	0.87
244_V	265_I	1.342	0.87
231_L	235_V	1.331	0.87
9_A	38_I	1.324	0.86
17_I	258_P	1.318	0.86
291_G	295_F	1.307	0.86
209_A	240_I	1.304	0.85
212_V	273_F	1.302	0.85
359_L	453_L	1.297	0.85
9_A	67_T	1.288	0.85
367_L	461_I	1.286	0.85
176_V	279_Y	1.273	0.84
42_T	50_N	1.273	0.84
313_A	411_G	1.256	0.83
412_I	451_I	1.254	0.83
30_K	96_I	1.251	0.83
45_S	203_K	1.244	0.83
328_W	343_Y	1.243	0.83
7_I	31_A	1.243	0.83
385_T	432_F	1.239	0.82
5_L	104_P	1.232	0.82
24_A	28_E	1.230	0.82
287_D	291_G	1.213	0.81
403_I	407_T	1.210	0.81
350_A	386_V	1.207	0.81
265_I	269_T	1.204	0.80
89_I	92_A	1.200	0.80
180_I	274_G	1.200	0.80
29_Q	32_R	1.199	0.80
398_A	464_K	1.198	0.80
87_I	91_Q	1.197	0.80
161_L	174_T	1.194	0.80
41_E	78_R	1.193	0.80
441_P	444_S	1.188	0.80
12_N	69_R	1.186	0.79
405_A	463_L	1.180	0.79
370_R	373_K	1.179	0.79
302_S	305_F	1.165	0.78
83_K	109_L	1.163	0.78
458_S	462_V	1.161	0.78
76_R	86_E	1.157	0.78
7_I	36_H	1.147	0.77
267_F	271_L	1.147	0.77
208_P	270_L	1.146	0.77
92_A	95_N	1.144	0.77
360_A	461_I	1.143	0.77
7_I	104_P	1.135	0.76
422_I	441_P	1.132	0.76
347_G	386_V	1.128	0.76
299_I	303_M	1.125	0.76
417_V	422_I	1.122	0.76
416_L	419_A	1.116	0.75
293_L	297_N	1.115	0.75
328_W	335_L	1.113	0.75
347_G	350_A	1.110	0.75
457_I	461_I	1.108	0.75
96_I	100_F	1.097	0.74
10_I	76_R	1.096	0.74
157_V	168_K	1.092	0.73
124_Q	127_S	1.086	0.73
448_V	451_I	1.082	0.73
29_Q	371_Q	1.080	0.73
53_S	56_E	1.077	0.72
285_M	326_T	1.066	0.72
102_E	105_T	1.061	0.71
243_F	273_F	1.060	0.71
91_Q	102_E	1.060	0.71
352_M	410_G	1.052	0.71
364_A	367_L	1.052	0.71
45_S	262_S	1.051	0.71
246_W	250_V	1.049	0.70
416_L	451_I	1.048	0.70
55_E	58_A	1.047	0.70
247_F	265_I	1.045	0.70
351_L	386_V	1.045	0.70
87_I	99_I	1.044	0.70
416_L	448_V	1.043	0.70
173_F	271_L	1.035	0.69
197_A	209_A	1.034	0.69
200_I	242_Y	1.031	0.69
127_S	131_H	1.028	0.69
315_L	347_G	1.027	0.69
291_G	294_H	1.025	0.69
370_R	374_E	1.023	0.68
76_R	110_F	1.021	0.68
107_S	110_F	1.020	0.68
285_M	288_L	1.019	0.68
404_T	463_L	1.017	0.68
289_M	326_T	1.017	0.68
195_Y	206_F	1.015	0.68
239_A	243_F	1.014	0.68
299_I	310_L	1.009	0.67
26_A	30_K	1.008	0.67
183_L	215_L	1.007	0.67
176_V	275_V	1.005	0.67
92_A	98_Q	1.004	0.67
122_E	126_G	1.000	0.67
210_F	214_Y	0.996	0.66
454_A	457_I	0.994	0.66
95_N	102_E	0.981	0.65
257_Q	260_L	0.977	0.65
416_L	444_S	0.976	0.65
422_I	440_S	0.975	0.65
62_Y	104_P	0.974	0.65
415_V	419_A	0.968	0.64
315_L	386_V	0.968	0.64
246_W	249_K	0.967	0.64
228_A	232_G	0.963	0.64
438_L	442_V	0.961	0.64
454_A	458_S	0.955	0.63
62_Y	106_N	0.954	0.63
26_A	93_L	0.953	0.63
353_P	410_G	0.952	0.63
323_I	407_T	0.945	0.62
140_L	260_L	0.944	0.62
315_L	350_A	0.942	0.62
67_T	86_E	0.934	0.61
311_V	342_W	0.932	0.61
252_L	260_L	0.923	0.60
248_R	388_T	0.923	0.60
357_A	379_A	0.921	0.60
51_R	75_D	0.916	0.60
209_A	213_C	0.916	0.60
156_L	173_F	0.913	0.60
65_L	76_R	0.912	0.59
453_L	457_I	0.911	0.59
29_Q	33_S	0.908	0.59
157_V	174_T	0.908	0.59
148_I	267_F	0.906	0.59
367_L	467_W	0.905	0.59
357_A	388_T	0.905	0.59
411_G	415_V	0.904	0.59
65_L	84_V	0.903	0.59
43_Q	65_L	0.903	0.59
193_G	233_A	0.901	0.59
134_A	138_A	0.899	0.58
124_Q	128_V	0.897	0.58
153_A	158_Q	0.893	0.58
276_L	280_V	0.890	0.58
85_Y	99_I	0.889	0.58
332_F	343_Y	0.888	0.57
319_M	406_N	0.883	0.57
10_I	67_T	0.883	0.57
247_F	269_T	0.882	0.57
58_A	61_D	0.882	0.57
34_L	96_I	0.881	0.57
459_F	463_L	0.881	0.57
159_F	162_P	0.879	0.57
90_S	94_K	0.877	0.56
5_L	37_T	0.877	0.56
292_L	295_F	0.874	0.56
247_F	250_V	0.872	0.56
328_W	351_L	0.868	0.56
202_D	248_R	0.868	0.56
305_F	419_A	0.867	0.56
62_Y	96_I	0.863	0.55
404_T	407_T	0.858	0.55
363_I	453_L	0.856	0.55
347_G	351_L	0.855	0.55
352_M	413_T	0.852	0.54
83_K	107_S	0.851	0.54
244_V	247_F	0.851	0.54
45_S	261_G	0.847	0.54
304_K	421_G	0.844	0.54
120_K	123_V	0.841	0.53
162_P	166_M	0.838	0.53
7_I	62_Y	0.838	0.53
351_L	432_F	0.837	0.53
408_L	412_I	0.835	0.53
197_A	205_A	0.833	0.53
129_M	133_M	0.832	0.53
343_Y	346_V	0.830	0.52
160_G	174_T	0.829	0.52
424_R	445_F	0.829	0.52
309_F	411_G	0.828	0.52
187_F	210_F	0.826	0.52
43_Q	75_D	0.824	0.52
100_F	104_P	0.824	0.52
288_L	323_I	0.823	0.52
165_D	170_A	0.822	0.52
57_I	82_K	0.820	0.51
144_I	375_A	0.819	0.51
406_N	410_G	0.817	0.51
336_E	412_I	0.817	0.51
153_A	160_G	0.816	0.51
386_V	414_G	0.816	0.51
5_L	59_A	0.813	0.51
344_A	347_G	0.812	0.51
7_I	103_L	0.812	0.51
345_I	418_I	0.810	0.51
260_L	264_L	0.808	0.50
114_S	118_L	0.808	0.50
247_F	264_L	0.808	0.50
295_F	310_L	0.807	0.50
346_V	417_V	0.806	0.50
369_T	397_A	0.806	0.50
131_H	200_I	0.805	0.50
315_L	351_L	0.805	0.50
227_G	286_S	0.804	0.50
9_A	36_H	0.802	0.50
312_G	445_F	0.801	0.50
359_L	454_A	0.798	0.50
85_Y	91_Q	0.794	0.49
308_A	312_G	0.792	0.49
409_A	456_N	0.792	0.49
205_A	243_F	0.789	0.49
445_F	449_L	0.788	0.49
8_V	56_E	0.788	0.49
10_I	65_L	0.787	0.49
367_L	465_G	0.783	0.48
349_V	407_T	0.782	0.48
93_L	99_I	0.782	0.48
43_Q	78_R	0.781	0.48
96_I	104_P	0.779	0.48
258_P	358_G	0.778	0.48
215_L	365_P	0.777	0.48
62_Y	83_K	0.774	0.47
312_G	349_V	0.772	0.47
371_Q	374_E	0.768	0.47
333_S	336_E	0.767	0.47
215_L	282_G	0.766	0.47
406_N	456_N	0.764	0.47
144_I	262_S	0.763	0.46
252_L	264_L	0.762	0.46
156_L	170_A	0.759	0.46
284_V	394_Y	0.757	0.46
302_S	306_A	0.756	0.46
87_I	95_N	0.755	0.46
156_L	177_V	0.752	0.45
271_L	275_V	0.751	0.45
21_Y	397_A	0.751	0.45
63_V	84_V	0.751	0.45
156_L	160_G	0.749	0.45
211_L	270_L	0.749	0.45
256_L	385_T	0.746	0.45
43_Q	76_R	0.744	0.45
309_F	312_G	0.742	0.45
156_L	161_L	0.741	0.44
124_Q	242_Y	0.741	0.44
88_A	94_K	0.741	0.44
152_L	155_M	0.741	0.44
450_A	454_A	0.739	0.44
253_G	256_L	0.739	0.44
123_V	126_G	0.738	0.44
295_F	298_T	0.738	0.44
7_I	38_I	0.735	0.44
364_A	465_G	0.735	0.44
12_N	67_T	0.734	0.44
248_R	281_I	0.733	0.44
128_V	238_L	0.733	0.44
235_V	268_V	0.733	0.44
341_D	421_G	0.731	0.44
183_L	186_T	0.730	0.44
365_P	373_K	0.730	0.44
89_I	96_I	0.729	0.43
359_L	457_I	0.729	0.43
332_F	336_E	0.729	0.43
341_D	417_V	0.729	0.43
77_A	112_A	0.728	0.43
127_S	242_Y	0.724	0.43
6_R	56_E	0.722	0.43
43_Q	380_I	0.721	0.43
157_V	170_A	0.720	0.43
89_I	99_I	0.719	0.43
13_C	16_G	0.717	0.42
162_P	165_D	0.716	0.42
443_G	447_L	0.711	0.42
61_D	82_K	0.709	0.42
351_L	414_G	0.708	0.42
16_G	19_H	0.707	0.42
158_Q	174_T	0.707	0.42
45_S	208_P	0.707	0.42
16_G	20_T	0.706	0.41
457_I	467_W	0.705	0.41
269_T	273_F	0.704	0.41
67_T	238_L	0.702	0.41
54_S	458_S	0.700	0.41
13_C	19_H	0.700	0.41
13_C	20_T	0.699	0.41
7_I	441_P	0.698	0.41
335_L	343_Y	0.696	0.41
134_A	206_F	0.696	0.41
413_T	417_V	0.694	0.40
350_A	385_T	0.694	0.40
285_M	291_G	0.691	0.40
446_Y	450_A	0.691	0.40
204_P	248_R	0.690	0.40
359_L	362_F	0.689	0.40
162_P	170_A	0.688	0.40
161_L	178_E	0.688	0.40
331_C	382_V	0.688	0.40
208_P	269_T	0.687	0.40
319_M	354_P	0.687	0.40
173_F	177_V	0.686	0.40
203_K	261_G	0.684	0.40
309_F	313_A	0.684	0.40
31_A	34_L	0.683	0.40
328_W	332_F	0.683	0.40
369_T	372_E	0.682	0.39
35_G	451_I	0.681	0.39
43_Q	362_F	0.680	0.39
215_L	278_Y	0.679	0.39
259_L	264_L	0.678	0.39
62_Y	100_F	0.677	0.39
412_I	457_I	0.677	0.39
62_Y	89_I	0.677	0.39
165_D	168_K	0.676	0.39
30_K	101_S	0.675	0.39
422_I	438_L	0.674	0.39
401_P	405_A	0.672	0.39
193_G	212_V	0.671	0.38
328_W	386_V	0.670	0.38
250_V	268_V	0.667	0.38
28_E	96_I	0.666	0.38
131_H	242_Y	0.665	0.38
195_Y	248_R	0.664	0.38
148_I	211_L	0.663	0.38
155_M	158_Q	0.662	0.38
175_W	178_E	0.662	0.38
386_V	432_F	0.662	0.38
425_L	438_L	0.660	0.38
207_A	269_T	0.659	0.37
359_L	363_I	0.659	0.37
351_L	431_I	0.659	0.37
28_E	31_A	0.659	0.37
341_D	418_I	0.655	0.37
52_L	82_K	0.654	0.37
400_L	404_T	0.654	0.37
333_S	339_I	0.653	0.37
239_A	273_F	0.650	0.37
85_Y	210_F	0.649	0.37
417_V	445_F	0.649	0.37
289_M	379_A	0.647	0.37
317_F	406_N	0.646	0.36
233_A	273_F	0.646	0.36
432_F	436_I	0.645	0.36
334_L	339_I	0.642	0.36
158_Q	170_A	0.641	0.36
286_S	294_H	0.641	0.36
283_P	286_S	0.639	0.36
7_I	100_F	0.639	0.36
61_D	104_P	0.638	0.36
344_A	351_L	0.637	0.36
424_R	432_F	0.636	0.36
85_Y	106_N	0.636	0.36
448_V	455_L	0.633	0.35
188_M	233_A	0.633	0.35
443_G	455_L	0.632	0.35
205_A	244_V	0.631	0.35
138_A	203_K	0.631	0.35
8_V	39_K	0.630	0.35
201_A	245_F	0.629	0.35
347_G	432_F	0.628	0.35
45_S	49_E	0.628	0.35
123_V	127_S	0.627	0.35
292_L	310_L	0.627	0.35
56_E	59_A	0.624	0.35
363_I	457_I	0.623	0.35
160_G	170_A	0.622	0.34
303_M	306_A	0.622	0.34
136_V	143_V	0.621	0.34
343_Y	428_G	0.621	0.34
281_I	285_M	0.621	0.34
432_F	438_L	0.618	0.34
344_A	350_A	0.615	0.34
89_I	248_R	0.615	0.34
39_K	53_S	0.615	0.34
10_I	75_D	0.614	0.34
43_Q	52_L	0.613	0.34
157_V	167_S	0.612	0.34
234_V	333_S	0.611	0.34
193_G	197_A	0.611	0.34
63_V	82_K	0.606	0.33
144_I	203_K	0.604	0.33
34_L	58_A	0.604	0.33
106_N	110_F	0.602	0.33
299_I	453_L	0.602	0.33
155_M	168_K	0.602	0.33
428_G	433_D	0.601	0.33
312_G	348_V	0.601	0.33
7_I	107_S	0.601	0.33
91_Q	96_I	0.600	0.33
132_L	238_L	0.600	0.33
239_A	272_V	0.597	0.33
317_F	349_V	0.596	0.32
422_I	448_V	0.596	0.32
263_M	385_T	0.591	0.32
159_F	210_F	0.591	0.32
335_L	338_H	0.591	0.32
37_T	59_A	0.591	0.32
355_V	384_A	0.590	0.32
161_L	170_A	0.589	0.32
49_E	254_K	0.588	0.32
13_C	18_A	0.588	0.32
228_A	282_G	0.587	0.32
347_G	431_I	0.587	0.32
330_F	334_L	0.586	0.32
268_V	271_L	0.585	0.32
436_I	442_V	0.584	0.32
401_P	464_K	0.584	0.32
259_L	437_G	0.583	0.31
207_A	334_L	0.583	0.31
87_I	102_E	0.581	0.31
257_Q	369_T	0.580	0.31
415_V	418_I	0.580	0.31
344_A	417_V	0.579	0.31
39_K	63_V	0.579	0.31
200_I	238_L	0.578	0.31
8_V	339_I	0.578	0.31
155_M	159_F	0.578	0.31
154_N	350_A	0.578	0.31
176_V	180_I	0.577	0.31
294_H	297_N	0.576	0.31
356_A	360_A	0.575	0.31
402_M	406_N	0.574	0.31
150_V	178_E	0.574	0.31
46_S	49_E	0.574	0.31
442_V	446_Y	0.573	0.31
258_P	385_T	0.573	0.31
68_G	89_I	0.572	0.31
152_L	178_E	0.572	0.31
158_Q	165_D	0.572	0.31
37_T	264_L	0.572	0.31
153_A	159_F	0.572	0.31
298_T	301_P	0.571	0.31
272_V	281_I	0.571	0.31
357_A	406_N	0.571	0.31
36_H	61_D	0.567	0.30
288_L	295_F	0.566	0.30
136_V	174_T	0.566	0.30
68_G	349_V	0.565	0.30
25_E	254_K	0.565	0.30
7_I	92_A	0.565	0.30
276_L	312_G	0.563	0.30
233_A	342_W	0.563	0.30
114_S	119_G	0.562	0.30
83_K	106_N	0.561	0.30
234_V	267_F	0.561	0.30
154_N	386_V	0.560	0.30
122_E	125_S	0.559	0.30
214_Y	225_Q	0.559	0.30
259_L	342_W	0.559	0.30
234_V	415_V	0.558	0.30
345_I	350_A	0.558	0.30
175_W	335_L	0.557	0.29
62_Y	99_I	0.556	0.29
85_Y	102_E	0.555	0.29
284_V	342_W	0.554	0.29
21_Y	398_A	0.553	0.29
198_S	206_F	0.551	0.29
406_N	459_F	0.551	0.29
277_T	344_A	0.550	0.29
97_D	100_F	0.550	0.29
69_R	319_M	0.549	0.29
115_G	118_L	0.549	0.29
6_R	55_E	0.548	0.29
348_V	355_V	0.548	0.29
14_P	67_T	0.547	0.29
188_M	417_V	0.547	0.29
187_F	342_W	0.547	0.29
348_V	417_V	0.545	0.29
114_S	121_Q	0.544	0.29
48_V	202_D	0.543	0.28
154_N	347_G	0.543	0.28
306_A	310_L	0.541	0.28
284_V	288_L	0.541	0.28
444_S	451_I	0.540	0.28
157_V	165_D	0.539	0.28
179_S	182_Y	0.539	0.28
372_E	460_I	0.539	0.28
85_Y	107_S	0.539	0.28
335_L	416_L	0.539	0.28
320_G	324_N	0.538	0.28
267_F	426_A	0.537	0.28
67_T	99_I	0.537	0.28
436_I	439_M	0.536	0.28
360_A	456_N	0.536	0.28
233_A	329_F	0.536	0.28
462_V	466_L	0.536	0.28
328_W	350_A	0.535	0.28
308_A	415_V	0.535	0.28
71_L	247_F	0.535	0.28
231_L	410_G	0.535	0.28
99_I	102_E	0.534	0.28
195_Y	331_C	0.534	0.28
236_L	277_T	0.534	0.28
140_L	326_T	0.534	0.28
153_A	165_D	0.533	0.28
352_M	453_L	0.532	0.28
208_P	261_G	0.532	0.28
157_V	161_L	0.532	0.28
106_N	109_L	0.532	0.28
113_D	117_K	0.532	0.28
210_F	269_T	0.531	0.28
77_A	80_A	0.530	0.28
133_M	138_A	0.530	0.28
296_L	330_F	0.530	0.28
152_L	156_L	0.528	0.27
188_M	206_F	0.528	0.27
67_T	71_L	0.527	0.27
294_H	298_T	0.526	0.27
350_A	414_G	0.526	0.27
363_I	461_I	0.526	0.27
208_P	378_S	0.526	0.27
14_P	233_A	0.526	0.27
347_G	424_R	0.525	0.27
103_L	308_A	0.525	0.27
118_L	121_Q	0.525	0.27
128_V	400_L	0.525	0.27
350_A	432_F	0.525	0.27
447_L	450_A	0.524	0.27
153_A	255_A	0.524	0.27
43_Q	138_A	0.523	0.27
137_S	327_A	0.523	0.27
233_A	303_M	0.523	0.27
171_P	175_W	0.523	0.27
9_A	245_F	0.523	0.27
388_T	410_G	0.521	0.27
328_W	417_V	0.521	0.27
88_A	91_Q	0.521	0.27
250_V	272_V	0.521	0.27
331_C	437_G	0.520	0.27
167_S	170_A	0.520	0.27
158_Q	162_P	0.519	0.27
328_W	344_A	0.519	0.27
62_Y	105_T	0.519	0.27
352_M	357_A	0.517	0.27
92_A	99_I	0.517	0.27
250_V	403_I	0.516	0.27
25_E	49_E	0.515	0.26
409_A	452_G	0.515	0.26
408_L	455_L	0.515	0.26
423_K	448_V	0.515	0.26
363_I	458_S	0.514	0.26
64_I	85_Y	0.514	0.26
206_F	407_T	0.514	0.26
165_D	171_P	0.514	0.26
442_V	450_A	0.513	0.26
191_I	444_S	0.513	0.26
332_F	335_L	0.513	0.26
356_A	406_N	0.513	0.26
366_K	467_W	0.513	0.26
14_P	324_N	0.512	0.26
118_L	122_E	0.511	0.26
201_A	299_I	0.511	0.26
258_P	328_W	0.511	0.26
48_V	56_E	0.509	0.26
143_V	154_N	0.509	0.26
304_K	341_D	0.509	0.26
49_E	140_L	0.509	0.26
352_M	406_N	0.508	0.26
6_R	38_I	0.506	0.26
43_Q	69_R	0.506	0.26
354_P	379_A	0.506	0.26
140_L	144_I	0.506	0.26
88_A	153_A	0.505	0.26
156_L	176_V	0.505	0.26
334_L	340_Y	0.505	0.26
55_E	455_L	0.505	0.26
179_S	306_A	0.505	0.26
315_L	414_G	0.505	0.26
92_A	185_F	0.503	0.26
386_V	431_I	0.503	0.26
193_G	213_C	0.502	0.26
157_V	171_P	0.501	0.26
149_L	177_V	0.500	0.25
231_L	285_M	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2r48A	1	0.2174	100	0.786	Contact Map
3qnqA	2	0.7598	100	0.802	Contact Map
2r4qA	1	0.2112	100	0.828	Contact Map
2kyrA	1	0.2236	100	0.838	Contact Map
2m1zA	1	0.2195	100	0.846	Contact Map
4tn5A	2	0.234	100	0.85	Contact Map
4mgeA	3	0.2091	99.8	0.901	Contact Map
1e2bA	1	0.2153	99.7	0.909	Contact Map
2l2qA	1	0.2112	99.6	0.915	Contact Map
3czcA	1	0.1905	99	0.936	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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