GREMLIN Database
YIHQ - Alpha-glucosidase YihQ
UniProt: P32138 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11843
Length: 678 (575)
Sequences: 4106 (2760)
Seq/√Len: 115.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
315_Q318_S4.7901.00
274_T278_A4.4871.00
324_N400_G4.2051.00
240_T245_R4.0811.00
280_V562_T3.9481.00
273_D277_N3.8801.00
269_Q322_Q3.8291.00
274_T277_N3.7381.00
519_E622_G3.4921.00
597_D629_Y3.4171.00
196_H459_T3.2691.00
348_A354_L3.1871.00
594_Y608_L3.1871.00
321_K325_Q3.1741.00
605_Y626_W3.1701.00
241_A245_R3.1481.00
435_K439_E3.1261.00
351_H381_E3.0691.00
279_G563_T3.0611.00
572_L609_L3.0211.00
627_T650_T2.9961.00
347_E389_V2.9841.00
612_D666_S2.9211.00
317_D321_K2.9191.00
505_I528_S2.7901.00
606_Q614_L2.7401.00
352_G356_K2.6581.00
234_S237_E2.6571.00
625_D650_T2.6531.00
353_Y382_A2.6411.00
590_L606_Q2.6411.00
637_H640_T2.6131.00
634_N643_A2.6101.00
577_A581_K2.5791.00
616_A628_L2.5521.00
129_I187_F2.5161.00
346_E350_Q2.5041.00
231_T234_S2.4941.00
517_S621_E2.4551.00
634_N645_R2.3871.00
128_H140_D2.3321.00
387_K443_E2.3201.00
273_D326_E2.2801.00
279_G559_A2.2501.00
317_D397_L2.2271.00
233_I593_H2.2241.00
654_P657_K2.2171.00
282_V328_V2.2131.00
625_D652_N2.1931.00
651_V661_F2.1891.00
198_D223_T2.1841.00
384_A388_E2.1791.00
349_A362_D2.1721.00
186_T194_Y2.1691.00
272_L282_V2.1531.00
275_M545_N2.1461.00
380_P417_H2.1391.00
484_A620_E2.1261.00
232_Y595_E2.0551.00
345_C373_G2.0241.00
616_A626_W1.9971.00
250_P253_I1.9971.00
453_F466_T1.9941.00
600_T629_Y1.9881.00
375_V382_A1.9881.00
457_G461_S1.9871.00
630_L661_F1.9841.00
559_A563_T1.9591.00
560_R656_G1.9581.00
630_L649_V1.9571.00
494_A589_P1.9481.00
357_D361_G1.9451.00
227_E238_K1.9411.00
578_L582_S1.8831.00
620_E623_R1.8801.00
379_N382_A1.8791.00
505_I534_M1.8651.00
616_A661_F1.8581.00
308_W316_L1.8431.00
525_C558_F1.8351.00
254_Y576_V1.8231.00
637_H657_K1.8121.00
634_N664_A1.7971.00
318_S322_Q1.7961.00
618_V626_W1.7791.00
638_A660_V1.7731.00
198_D225_R1.7671.00
194_Y235_L1.7641.00
278_A553_E1.7441.00
588_R593_H1.7371.00
237_E582_S1.7291.00
76_P85_R1.7271.00
341_D346_E1.7141.00
487_V619_H1.7111.00
391_K443_E1.6981.00
608_L635_W1.6901.00
550_G554_T1.6891.00
381_E384_A1.6871.00
293_I333_Y1.6841.00
101_G105_L1.6801.00
576_V586_V1.6771.00
84_S96_S1.6501.00
268_C287_A1.6431.00
435_K464_Y1.6351.00
600_T603_L1.6241.00
239_L459_T1.6211.00
272_L328_V1.6021.00
615_V660_V1.5971.00
101_G104_L1.5761.00
266_E270_K1.5761.00
644_F661_F1.5451.00
273_D322_Q1.5351.00
584_L592_L1.5241.00
568_L613_I1.5221.00
262_Q265_T1.4941.00
287_A330_F1.4931.00
432_L435_K1.4921.00
229_A234_S1.4911.00
490_A501_H1.4901.00
503_S531_T1.4751.00
232_Y591_F1.4691.00
613_I668_W1.4651.00
332_A399_C1.4641.00
590_L608_L1.4521.00
554_T559_A1.4521.00
638_A670_A1.4501.00
283_N566_T1.4291.00
272_L285_I1.4271.00
555_I561_M1.4261.00
578_L611_R1.4201.00
76_P83_F1.4131.00
237_E584_L1.4071.00
354_L373_G1.4061.00
103_L106_E1.4021.00
188_V232_Y1.3971.00
100_Q105_L1.3971.00
150_T183_P1.3871.00
348_A373_G1.3851.00
251_D573_K1.3841.00
379_N417_H1.3791.00
102_R105_L1.3741.00
561_M658_P1.3651.00
347_E351_H1.3571.00
82_H96_S1.3571.00
387_K440_A1.3541.00
613_I662_Y1.3531.00
527_F607_Y1.3421.00
276_R326_E1.3391.00
522_L655_I1.3381.00
249_L254_Y1.3341.00
578_L584_L1.3261.00
391_K396_E1.3251.00
638_A662_Y1.3191.00
636_V664_A1.3161.00
630_L651_V1.3141.00
298_F301_R1.3081.00
257_V286_W1.3071.00
391_K444_T1.3071.00
575_A578_L1.2971.00
470_A489_A1.2920.99
264_G267_V1.2850.99
483_L527_F1.2830.99
522_L526_D1.2810.99
346_E349_A1.2770.99
197_V217_L1.2760.99
71_I75_S1.2760.99
590_L603_L1.2740.99
64_K68_T1.2730.99
477_W519_E1.2720.99
628_L651_V1.2680.99
187_F207_F1.2630.99
362_D373_G1.2620.99
353_Y379_N1.2610.99
380_P384_A1.2600.99
356_K362_D1.2590.99
613_I660_V1.2560.99
515_K541_R1.2510.99
530_F660_V1.2490.99
275_M282_V1.2470.99
519_E655_I1.2460.99
132_C207_F1.2450.99
256_G275_M1.2450.99
320_I330_F1.2380.99
100_Q103_L1.2370.99
637_H642_E1.2300.99
129_I189_S1.2260.99
355_A374_V1.2250.99
71_I74_Q1.2210.99
243_L462_Q1.2200.99
431_A461_S1.2160.99
549_D553_E1.2140.99
551_D554_T1.2120.99
123_A129_I1.2090.99
383_Y436_C1.2060.99
84_S94_N1.2050.99
531_T607_Y1.2000.99
612_D663_R1.2000.99
252_W401_G1.1950.99
227_E242_L1.1930.99
384_A443_E1.1900.99
388_E391_K1.1860.99
499_G579_N1.1850.99
91_A95_I1.1840.99
182_F457_G1.1820.99
477_W621_E1.1710.99
233_I584_L1.1710.99
272_L323_W1.1590.99
236_L592_L1.1580.99
145_P206_D1.1530.99
229_A235_L1.1510.99
607_Y615_V1.1510.99
78_G81_I1.1500.99
333_Y403_M1.1500.99
519_E621_E1.1470.99
128_H602_T1.1440.99
522_L555_I1.1390.99
329_Q400_G1.1370.99
593_H611_R1.1340.99
455_R472_D1.1330.99
383_Y387_K1.1300.99
653_A657_K1.1300.99
186_T235_L1.1300.99
388_E392_K1.1270.99
101_G107_L1.1260.99
405_D472_D1.1250.99
546_W549_D1.1240.99
331_L401_G1.1170.99
309_N312_N1.1150.99
383_Y439_E1.1120.98
189_S192_K1.1110.98
628_L661_F1.1080.98
320_I399_C1.1050.98
348_A385_W1.1050.98
639_W657_K1.1020.98
439_E442_E1.1010.98
272_L326_E1.0930.98
644_F649_V1.0920.98
575_A586_V1.0910.98
392_K396_E1.0900.98
72_V76_P1.0880.98
594_Y663_R1.0870.98
390_I402_W1.0820.98
563_T673_A1.0790.98
469_W472_D1.0780.98
276_R328_V1.0780.98
589_P592_L1.0760.98
97_A103_L1.0710.98
387_K439_E1.0680.98
490_A503_S1.0640.98
364_L373_G1.0620.98
349_A354_L1.0610.98
536_T543_G1.0600.98
323_W328_V1.0590.98
203_M217_L1.0590.98
258_T275_M1.0570.98
301_R341_D1.0500.98
318_S321_K1.0500.98
132_C187_F1.0500.98
321_K324_N1.0490.98
322_Q325_Q1.0480.98
468_M493_L1.0480.98
438_Y442_E1.0470.98
280_V553_E1.0460.98
259_L286_W1.0410.98
593_H663_R1.0400.98
549_D552_A1.0390.98
83_F93_L1.0330.98
256_G536_T1.0260.97
258_T263_G1.0230.97
431_A463_K1.0230.97
506_G521_L1.0210.97
101_G106_E1.0140.97
256_G534_M1.0130.97
269_Q326_E1.0130.97
490_A587_M1.0120.97
529_A561_M1.0080.97
344_L389_V1.0060.97
67_L70_A1.0030.97
593_H608_L1.0010.97
245_R583_G1.0010.97
571_Y669_A0.9970.97
270_K274_T0.9960.97
269_Q319_R0.9960.97
324_N329_Q0.9950.97
263_G544_D0.9940.97
353_Y381_E0.9910.97
449_E573_K0.9880.97
567_T670_A0.9880.97
470_A493_L0.9850.97
345_C362_D0.9840.97
530_F615_V0.9820.97
662_Y668_W0.9770.97
477_W520_L0.9770.97
123_A142_R0.9750.97
510_T516_R0.9750.97
301_R305_N0.9710.96
338_V348_A0.9690.96
431_A464_Y0.9690.96
618_V654_P0.9650.96
612_D668_W0.9610.96
91_A103_L0.9600.96
230_D238_K0.9590.96
518_K549_D0.9590.96
184_Q243_L0.9570.96
334_I390_I0.9520.96
240_T499_G0.9520.96
491_L589_P0.9480.96
522_L558_F0.9480.96
87_S90_S0.9470.96
103_L107_L0.9460.96
531_T587_M0.9440.96
65_I69_D0.9430.96
268_C285_I0.9420.96
147_P204_N0.9410.96
99_D103_L0.9390.96
267_V270_K0.9360.96
228_C238_K0.9360.96
246_Q499_G0.9330.96
560_R563_T0.9320.95
72_V85_R0.9310.95
421_S424_I0.9300.95
405_D455_R0.9300.95
249_L576_V0.9280.95
579_N586_V0.9280.95
383_Y435_K0.9280.95
521_L558_F0.9230.95
240_T583_G0.9220.95
560_R657_K0.9210.95
416_L422_A0.9200.95
364_L371_Y0.9150.95
249_L500_L0.9150.95
352_G379_N0.9120.95
197_V203_M0.9120.95
653_A658_P0.9120.95
558_F562_T0.9110.95
521_L536_T0.9100.95
201_C219_E0.9090.95
578_L588_R0.9080.95
266_E269_Q0.9080.95
139_F491_L0.9020.95
85_R93_L0.9020.95
491_L587_M0.9010.95
653_A661_F0.9000.95
91_A94_N0.9000.95
454_M468_M0.9000.95
100_Q104_L0.8950.94
76_P81_I0.8940.94
254_Y572_L0.8930.94
233_I592_L0.8890.94
184_Q459_T0.8880.94
124_Q191_Q0.8880.94
530_F658_P0.8880.94
70_A73_S0.8860.94
594_Y633_D0.8820.94
483_L619_H0.8800.94
284_G329_Q0.8770.94
287_A313_Y0.8760.94
255_D283_N0.8750.94
97_A106_E0.8740.94
79_W83_F0.8740.94
267_V542_P0.8720.94
597_D600_T0.8660.93
561_M639_W0.8650.93
455_R469_W0.8640.93
91_A97_A0.8620.93
89_I95_I0.8620.93
307_K343_D0.8590.93
73_S84_S0.8580.93
70_A75_S0.8560.93
239_L243_L0.8560.93
225_R242_L0.8560.93
64_K67_L0.8550.93
597_D632_E0.8520.93
442_E447_L0.8520.93
317_D396_E0.8510.93
477_W483_L0.8500.93
530_F564_V0.8470.93
83_F95_I0.8470.93
248_E573_K0.8430.92
486_V531_T0.8420.92
65_I68_T0.8420.92
260_G288_Q0.8410.92
72_V75_S0.8400.92
95_I103_L0.8350.92
495_M591_F0.8350.92
269_Q323_W0.8340.92
525_C536_T0.8340.92
608_L612_D0.8310.92
94_N106_E0.8300.92
355_A410_L0.8300.92
76_P79_W0.8290.92
271_K546_W0.8280.92
529_A534_M0.8280.92
494_A585_P0.8260.92
550_G553_E0.8220.91
494_A587_M0.8180.91
248_E577_A0.8180.91
186_T239_L0.8180.91
288_Q472_D0.8180.91
528_S534_M0.8180.91
192_K230_D0.8150.91
297_S300_K0.8140.91
128_H601_Y0.8130.91
349_A373_G0.8120.91
522_L552_A0.8090.91
469_W537_H0.8090.91
261_I294_R0.8040.91
395_I441_L0.7990.90
92_T95_I0.7980.90
199_N220_D0.7970.90
276_R283_N0.7950.90
126_E598_A0.7950.90
102_R106_E0.7940.90
62_Q66_A0.7940.90
100_Q106_E0.7930.90
352_G362_D0.7910.90
590_L600_T0.7890.90
411_P416_L0.7890.90
85_R103_L0.7870.90
335_N406_F0.7870.90
566_T573_K0.7850.89
299_G311_E0.7850.89
90_S96_S0.7840.89
99_D102_R0.7820.89
259_L537_H0.7820.89
470_A490_A0.7800.89
518_K552_A0.7800.89
470_A501_H0.7790.89
441_L452_F0.7780.89
461_S498_H0.7740.89
566_T569_K0.7740.89
476_D482_G0.7740.89
181_F471_G0.7730.89
351_H388_E0.7650.88
384_A387_K0.7640.88
248_E576_V0.7640.88
500_L576_V0.7630.88
461_S465_S0.7630.88
121_L224_L0.7610.88
190_T601_Y0.7600.88
268_C330_F0.7590.88
257_V284_G0.7590.88
275_M279_G0.7590.88
366_E371_Y0.7550.88
527_F531_T0.7550.88
410_L414_T0.7540.87
119_L224_L0.7520.87
571_Y610_G0.7520.87
402_W441_L0.7520.87
237_E245_R0.7500.87
99_D105_L0.7490.87
308_W397_L0.7480.87
261_I333_Y0.7470.87
389_V393_N0.7470.87
91_A96_S0.7460.87
187_F195_C0.7460.87
214_E217_L0.7460.87
608_L631_P0.7460.87
132_C146_F0.7460.87
77_D82_H0.7430.87
323_W330_F0.7430.87
149_W202_Y0.7430.87
407_G433_W0.7430.87
278_A546_W0.7410.87
99_D106_E0.7410.87
72_V83_F0.7400.87
575_A608_L0.7390.86
416_L419_G0.7380.86
603_L606_Q0.7370.86
405_D408_E0.7350.86
218_W423_E0.7340.86
434_A465_S0.7330.86
579_N582_S0.7330.86
87_S92_T0.7320.86
523_R526_D0.7300.86
591_F601_Y0.7290.86
471_G508_Y0.7280.86
345_C354_L0.7280.86
422_A426_H0.7280.86
490_A531_T0.7270.86
348_A353_Y0.7270.86
545_N558_F0.7260.85
62_Q67_L0.7240.85
605_Y619_H0.7240.85
599_H602_T0.7230.85
74_Q88_D0.7200.85
96_S103_L0.7200.85
67_L85_R0.7190.85
394_M399_C0.7190.85
282_V285_I0.7190.85
320_I397_L0.7180.85
97_A102_R0.7180.85
396_E444_T0.7170.85
62_Q68_T0.7170.85
575_A579_N0.7150.85
254_Y586_V0.7150.85
145_P204_N0.7140.85
120_R214_E0.7130.84
599_H629_Y0.7100.84
249_L253_I0.7100.84
495_M589_P0.7090.84
407_G454_M0.7090.84
461_S468_M0.7040.84
90_S95_I0.7040.84
663_R666_S0.7030.84
637_H644_F0.7020.84
525_C534_M0.7020.84
564_V660_V0.7010.83
469_W508_Y0.6990.83
97_A101_G0.6990.83
184_Q496_T0.6980.83
394_M398_G0.6970.83
270_K273_D0.6960.83
666_S669_A0.6940.83
98_D101_G0.6930.83
553_E559_A0.6920.83
454_M465_S0.6890.82
340_S371_Y0.6890.82
347_E350_Q0.6890.82
100_Q107_L0.6880.82
212_Y216_A0.6880.82
286_W533_M0.6870.82
182_F468_M0.6870.82
73_S82_H0.6860.82
123_A208_S0.6860.82
618_V623_R0.6850.82
64_K69_D0.6840.82
132_C205_F0.6840.82
516_R543_G0.6830.82
282_V546_W0.6820.82
99_D104_L0.6820.82
215_L218_W0.6810.82
212_Y217_L0.6790.81
93_L102_R0.6760.81
526_D560_R0.6760.81
626_W651_V0.6750.81
386_F437_N0.6740.81
457_G498_H0.6740.81
63_E71_I0.6710.81
90_S106_E0.6700.81
196_H239_L0.6680.80
93_L96_S0.6680.80
504_D535_R0.6680.80
240_T585_P0.6680.80
575_A611_R0.6660.80
271_K275_M0.6660.80
618_V622_G0.6650.80
468_M498_H0.6650.80
590_L631_P0.6640.80
573_K577_A0.6640.80
555_I655_I0.6640.80
441_L450_I0.6630.80
470_A473_Q0.6600.80
526_D656_G0.6590.79
85_R95_I0.6590.79
252_W329_Q0.6590.79
472_D537_H0.6580.79
587_M607_Y0.6570.79
629_Y632_E0.6550.79
389_V392_K0.6540.79
618_V653_A0.6540.79
139_F591_F0.6540.79
595_E600_T0.6540.79
322_Q326_E0.6530.79
633_D646_G0.6520.79
148_L183_P0.6520.79
248_E580_A0.6520.79
646_G649_V0.6520.79
637_H661_F0.6500.79
590_L629_Y0.6500.79
261_I335_N0.6500.79
200_S458_S0.6490.78
251_D569_K0.6480.78
621_E624_S0.6470.78
378_T420_V0.6470.78
284_G331_L0.6460.78
97_A104_L0.6460.78
96_S101_G0.6460.78
83_F92_T0.6460.78
197_V224_L0.6440.78
200_S428_A0.6440.78
265_T312_N0.6430.78
95_I106_E0.6420.78
575_A588_R0.6410.78
258_T544_D0.6410.78
134_E489_A0.6400.77
275_M546_W0.6400.77
236_L240_T0.6400.77
243_L459_T0.6390.77
639_W660_V0.6390.77
65_I70_A0.6390.77
68_T72_V0.6380.77
413_D416_L0.6380.77
231_T595_E0.6360.77
636_V643_A0.6360.77
653_A659_P0.6360.77
256_G558_F0.6350.77
608_L663_R0.6340.77
187_F193_Y0.6330.77
386_F433_W0.6320.77
644_F648_E0.6320.77
324_N330_F0.6310.76
340_S345_C0.6290.76
378_T432_L0.6290.76
252_W284_G0.6280.76
94_N97_A0.6280.76
61_L64_K0.6270.76
214_E218_W0.6270.76
530_F609_L0.6270.76
355_A414_T0.6270.76
70_A74_Q0.6260.76
347_E388_E0.6260.76
137_S146_F0.6260.76
548_F551_D0.6260.76
184_Q498_H0.6250.76
75_S85_R0.6240.76
104_L107_L0.6240.76
82_H99_D0.6240.76
494_A579_N0.6230.76
377_L436_C0.6220.75
507_G524_W0.6210.75
63_E68_T0.6200.75
409_Y416_L0.6190.75
280_V559_A0.6190.75
91_A101_G0.6180.75
603_L629_Y0.6180.75
199_N203_M0.6170.75
335_N369_E0.6170.75
298_F310_S0.6160.75
258_T285_I0.6140.75
85_R90_S0.6130.74
85_R92_T0.6130.74
631_P635_W0.6130.74
405_D537_H0.6120.74
261_I293_I0.6120.74
98_D102_R0.6120.74
474_N509_T0.6120.74
606_Q616_A0.6110.74
443_E446_K0.6100.74
183_P427_N0.6100.74
67_L72_V0.6090.74
391_K395_I0.6090.74
61_L68_T0.6080.74
542_P547_Q0.6080.74
488_P492_S0.6080.74
237_E240_T0.6070.74
318_S325_Q0.6060.74
72_V78_G0.6060.74
108_Q111_N0.6060.74
552_A558_F0.6040.73
89_I92_T0.6040.73
347_E353_Y0.6030.73
96_S99_D0.6020.73
555_I656_G0.6010.73
85_R88_D0.6010.73
434_A454_M0.6000.73
347_E385_W0.5990.73
64_K72_V0.5980.73
526_D658_P0.5980.73
636_V665_D0.5960.72
70_A85_R0.5950.72
127_D191_Q0.5940.72
271_K544_D0.5930.72
455_R537_H0.5930.72
630_L646_G0.5920.72
430_P456_A0.5920.72
137_S141_L0.5910.72
94_N103_L0.5900.72
97_A100_Q0.5900.72
345_C349_A0.5900.72
623_R626_W0.5900.72
129_I207_F0.5900.72
187_F213_H0.5890.71
505_I529_A0.5890.71
409_Y413_D0.5880.71
569_K573_K0.5870.71
139_F492_S0.5850.71
283_N573_K0.5850.71
154_G509_T0.5840.71
256_G545_N0.5830.71
484_A488_P0.5830.71
375_V436_C0.5820.71
545_N562_T0.5820.71
68_T73_S0.5810.70
455_R471_G0.5800.70
440_A443_E0.5790.70
255_D565_F0.5790.70
71_I76_P0.5790.70
236_L495_M0.5780.70
269_Q273_D0.5750.70
288_Q403_M0.5750.70
94_N99_D0.5750.70
534_M562_T0.5750.70
523_R618_V0.5750.70
233_I611_R0.5740.70
192_K235_L0.5740.70
197_V205_F0.5730.69
78_G97_A0.5730.69
273_D276_R0.5720.69
344_L347_E0.5720.69
61_L65_I0.5710.69
411_P414_T0.5710.69
261_I406_F0.5710.69
87_S94_N0.5710.69
93_L97_A0.5710.69
637_H641_G0.5700.69
96_S102_R0.5700.69
66_A72_V0.5690.69
254_Y573_K0.5690.69
117_I121_L0.5690.69
251_D671_L0.5680.69
288_Q455_R0.5680.69
332_A402_W0.5670.69
436_C440_A0.5670.69
83_F103_L0.5670.69
395_I445_G0.5660.68
201_C424_I0.5650.68
232_Y601_Y0.5640.68
519_E624_S0.5640.68
270_K277_N0.5630.68
390_I399_C0.5630.68
109_N113_N0.5630.68
240_T497_G0.5620.68
473_Q482_G0.5610.68
85_R89_I0.5610.68
215_L224_L0.5600.68
69_D88_D0.5600.68
68_T75_S0.5600.68
95_I107_L0.5590.68
93_L104_L0.5580.67
85_R97_A0.5580.67
508_Y537_H0.5580.67
390_I437_N0.5580.67
73_S350_Q0.5570.67
343_D346_E0.5570.67
260_G544_D0.5570.67
79_W85_R0.5570.67
117_I219_E0.5560.67
258_T271_K0.5540.67
283_N565_F0.5540.67
123_A213_H0.5540.67
95_I226_F0.5520.67
590_L616_A0.5520.67
181_F406_F0.5520.67
494_A499_G0.5500.66
133_G496_T0.5500.66
335_N403_M0.5480.66
420_V425_M0.5480.66
472_D504_D0.5470.66
288_Q535_R0.5460.66
74_Q77_D0.5460.66
403_M406_F0.5450.66
384_A439_E0.5450.66
89_I93_L0.5450.66
384_A596_D0.5450.66
260_G263_G0.5440.65
91_A104_L0.5440.65
560_R567_T0.5440.65
63_E69_D0.5440.65
410_L416_L0.5430.65
74_Q83_F0.5430.65
451_L466_T0.5430.65
204_N216_A0.5430.65
199_N219_E0.5420.65
74_Q85_R0.5420.65
108_Q112_L0.5410.65
504_D507_G0.5410.65
288_Q333_Y0.5400.65
353_Y385_W0.5400.65
295_M394_M0.5370.64
578_L593_H0.5370.64
615_V658_P0.5360.64
475_V543_G0.5350.64
626_W653_A0.5350.64
405_D469_W0.5350.64
340_S364_L0.5340.64
334_I402_W0.5330.64
127_D193_Y0.5330.64
403_M537_H0.5330.64
308_W317_D0.5330.64
408_E504_D0.5320.64
268_C319_R0.5310.64
408_E469_W0.5310.64
247_P580_A0.5300.63
487_V607_Y0.5300.63
257_V533_M0.5300.63
63_E73_S0.5300.63
522_L551_D0.5300.63
365_V374_V0.5280.63
76_P95_I0.5280.63
402_W437_N0.5280.63
564_V638_A0.5270.63
81_I228_C0.5270.63
67_L71_I0.5260.63
91_A106_E0.5250.63
61_L66_A0.5240.63
135_Q141_L0.5220.62
90_S97_A0.5220.62
518_K551_D0.5220.62
406_F535_R0.5220.62
538_E542_P0.5220.62
640_T643_A0.5220.62
611_R666_S0.5220.62
90_S94_N0.5220.62
665_D669_A0.5210.62
82_H85_R0.5200.62
94_N104_L0.5200.62
98_D103_L0.5200.62
184_Q468_M0.5200.62
75_S82_H0.5200.62
471_G537_H0.5190.62
92_T97_A0.5190.62
248_E449_E0.5190.62
81_I85_R0.5190.62
387_K436_C0.5190.62
351_H379_N0.5180.62
129_I132_C0.5170.62
92_T96_S0.5170.62
88_D91_A0.5170.62
546_W553_E0.5150.61
93_L99_D0.5150.61
307_K393_N0.5150.61
439_E464_Y0.5150.61
212_Y215_L0.5150.61
340_S373_G0.5150.61
551_D656_G0.5150.61
193_Y224_L0.5140.61
112_L117_I0.5140.61
73_S77_D0.5140.61
99_D107_L0.5140.61
337_Y372_G0.5140.61
85_R104_L0.5110.61
67_L83_F0.5100.61
90_S93_L0.5100.61
73_S76_P0.5090.60
264_G312_N0.5090.60
504_D508_Y0.5080.60
184_Q462_Q0.5080.60
268_C323_W0.5070.60
443_E447_L0.5060.60
584_L611_R0.5060.60
333_Y508_Y0.5050.60
269_Q272_L0.5040.60
109_N112_L0.5040.60
186_T196_H0.5040.60
255_D566_T0.5040.60
306_W386_F0.5040.60
79_W82_H0.5040.60
630_L647_G0.5030.59
88_D92_T0.5030.59
89_I98_D0.5030.59
484_A605_Y0.5030.59
74_Q79_W0.5030.59
261_I508_Y0.5030.59
606_Q617_P0.5030.59
403_M470_A0.5020.59
567_T672_F0.5020.59
403_M508_Y0.5020.59
475_V536_T0.5010.59
114_H118_W0.5010.59
403_M407_G0.5000.59
564_V639_W0.5000.59
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3lppA 3 0.9395 100 0.127 Contact Map
3l4yA 1 0.9395 100 0.132 Contact Map
3weoA 1 0.9336 100 0.139 Contact Map
4ba0A 2 0.9277 100 0.14 Contact Map
3topA 1 0.9351 100 0.143 Contact Map
4kmqA 1 0.9292 100 0.167 Contact Map
2f2hA 4 0.9277 100 0.168 Contact Map
2xvlA 1 0.9351 100 0.177 Contact Map
3nsxA 2 0.8319 100 0.186 Contact Map
4amwA 1 0.9676 100 0.202 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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