GREMLIN Database
YIBJ - Putative uncharacterized protein YibJ
UniProt: P32109 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11766
Length: 233 (188)
Sequences: 423 (401)
Seq/√Len: 29.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
76_D80_N5.9891.00
109_Y114_Y5.6941.00
127_P152_L3.7931.00
99_Q110_N3.6751.00
99_Q111_R3.4631.00
30_T33_Q3.4581.00
52_H63_I3.2821.00
95_R108_Y2.3650.99
110_N122_Y2.3390.99
110_N141_L2.0880.98
64_S68_A2.0840.98
209_G213_D2.0660.97
110_N130_L2.0180.97
100_Q110_N1.9940.97
142_N145_I1.9040.96
54_D58_L1.8950.96
110_N132_G1.8550.95
71_W110_N1.8030.94
73_A96_L1.7770.94
99_Q130_L1.7570.93
128_I132_G1.7390.93
99_Q108_Y1.6630.91
204_L207_F1.6320.91
139_Y148_D1.6190.90
73_A76_D1.6170.90
58_L75_Y1.5900.89
94_I100_Q1.5800.89
96_L136_F1.5690.89
192_T209_G1.5670.89
47_K66_E1.5490.88
99_Q109_Y1.5200.87
97_P100_Q1.5160.87
107_L123_I1.5030.86
205_I211_Y1.4910.86
73_A108_Y1.4850.86
175_G186_T1.4760.85
95_R100_Q1.4710.85
208_D213_D1.4710.85
128_I152_L1.4670.85
162_D166_S1.4660.85
111_R150_Q1.4400.84
62_L78_W1.4380.84
125_Q136_F1.4310.84
139_Y149_P1.4120.83
130_L133_G1.4050.82
173_I177_F1.3790.81
172_N179_I1.3740.81
73_A82_L1.3680.81
165_H168_A1.3530.80
97_P108_Y1.3280.79
110_N136_F1.3200.78
116_D119_L1.3170.78
126_D151_G1.3100.78
102_D114_Y1.3080.78
58_L73_A1.3000.77
30_T35_K1.2690.75
33_Q37_Q1.2670.75
97_P110_N1.2490.74
49_H70_A1.2380.74
202_A206_K1.2140.72
58_L96_L1.1980.71
201_L211_Y1.1960.71
170_E173_I1.1940.71
75_Y122_Y1.1890.70
104_E114_Y1.1850.70
209_G212_K1.1700.69
122_Y150_Q1.1560.68
110_N133_G1.1410.67
25_A28_G1.1410.67
129_G133_G1.1300.66
54_D73_A1.1260.66
179_I200_D1.1260.66
112_H149_P1.1240.66
99_Q122_Y1.1200.66
108_Y114_Y1.1190.66
51_Y62_L1.1140.65
95_R129_G1.1070.65
107_L152_L1.1030.65
146_N154_D1.0970.64
120_G137_Y1.0960.64
128_I133_G1.0900.64
97_P130_L1.0890.64
97_P122_Y1.0780.63
35_K39_D1.0620.62
100_Q111_R1.0560.61
169_D196_M1.0510.61
58_L97_P1.0500.61
99_Q127_P1.0460.60
53_C59_P1.0370.60
125_Q130_L1.0360.60
100_Q122_Y1.0340.59
56_R97_P1.0330.59
190_S194_S1.0310.59
187_S195_I1.0310.59
111_R114_Y1.0280.59
95_R101_Y1.0180.58
86_N96_L1.0150.58
191_A195_I1.0110.58
53_C73_A1.0050.57
159_P188_I1.0010.57
73_A130_L0.9980.57
59_P75_Y0.9960.57
170_E186_T0.9950.56
59_P152_L0.9940.56
198_A203_Y0.9760.55
202_A210_N0.9710.55
29_L32_E0.9690.54
99_Q128_I0.9570.54
165_H169_D0.9500.53
111_R125_Q0.9410.52
181_G185_P0.9400.52
196_M201_L0.9370.52
111_R122_Y0.9260.51
185_P191_A0.9190.51
95_R133_G0.9160.50
71_W99_Q0.9090.50
57_G120_G0.9080.50
93_L100_Q0.9070.50
46_R142_N0.9050.49
197_T200_D0.9010.49
187_S197_T0.9000.49
205_I213_D0.8980.49
189_E193_R0.8970.49
130_L152_L0.8940.49
169_D173_I0.8910.48
111_R130_L0.8890.48
112_H130_L0.8850.48
164_I171_I0.8800.47
29_L33_Q0.8750.47
206_K210_N0.8690.47
57_G127_P0.8590.46
196_M199_K0.8500.45
99_Q133_G0.8450.45
174_P181_G0.8410.44
122_Y140_P0.8400.44
92_Q122_Y0.8390.44
130_L134_W0.8390.44
162_D165_H0.8350.44
121_R141_L0.8340.44
116_D139_Y0.8320.44
176_V190_S0.8310.44
210_N213_D0.8100.42
126_D148_D0.8070.42
148_D151_G0.8070.42
62_L67_G0.8040.42
161_S188_I0.8040.42
81_L84_D0.8000.41
182_H191_A0.7980.41
77_E80_N0.7850.40
156_N188_I0.7770.40
102_D105_S0.7660.39
99_Q114_Y0.7650.39
166_S170_E0.7620.38
96_L110_N0.7620.38
115_Y120_G0.7610.38
107_L127_P0.7580.38
188_I192_T0.7570.38
94_I111_R0.7480.37
122_Y138_Q0.7440.37
63_I142_N0.7390.37
33_Q76_D0.7390.37
174_P197_T0.7370.37
168_A173_I0.7330.36
61_A78_W0.7300.36
51_Y75_Y0.7270.36
178_T181_G0.7250.36
198_A208_D0.7190.35
113_R151_G0.7180.35
113_R126_D0.7180.35
163_L167_V0.7100.35
94_I129_G0.7040.34
111_R121_R0.7030.34
33_Q36_N0.7000.34
205_I212_K0.7000.34
100_Q108_Y0.6970.34
73_A92_Q0.6960.34
44_P49_H0.6950.34
153_V157_L0.6950.34
72_C81_L0.6940.34
65_T68_A0.6930.33
97_P141_L0.6910.33
185_P189_E0.6890.33
181_G200_D0.6880.33
198_A202_A0.6810.33
179_I199_K0.6780.32
186_T191_A0.6770.32
197_T211_Y0.6740.32
30_T38_M0.6700.32
57_G98_G0.6660.32
95_R99_Q0.6660.32
156_N167_V0.6620.31
99_Q104_E0.6620.31
182_H187_S0.6620.31
58_L78_W0.6620.31
200_D203_Y0.6570.31
55_H73_A0.6490.30
112_H150_Q0.6460.30
185_P196_M0.6420.30
183_G202_A0.6410.30
36_N39_D0.6400.30
163_L170_E0.6340.29
191_A197_T0.6280.29
191_A209_G0.6210.29
164_I168_A0.6190.29
58_L77_E0.6140.28
32_E39_D0.6100.28
55_H58_L0.6070.28
182_H186_T0.6060.28
156_N177_F0.6060.28
157_L199_K0.6040.28
184_T188_I0.6030.27
81_L131_K0.6020.27
122_Y135_N0.6020.27
203_Y207_F0.6010.27
160_E170_E0.6010.27
185_P209_G0.6010.27
174_P177_F0.6000.27
52_H78_W0.5980.27
102_D109_Y0.5980.27
65_T98_G0.5960.27
192_T203_Y0.5960.27
92_Q124_T0.5960.27
112_H133_G0.5950.27
101_Y108_Y0.5900.27
101_Y114_Y0.5880.27
99_Q150_Q0.5870.27
171_I176_V0.5860.26
170_E203_Y0.5860.26
78_W97_P0.5840.26
167_V170_E0.5830.26
176_V185_P0.5820.26
180_G183_G0.5810.26
127_P150_Q0.5810.26
187_S192_T0.5810.26
77_E92_Q0.5790.26
207_F213_D0.5780.26
97_P111_R0.5780.26
173_I184_T0.5770.26
122_Y152_L0.5720.26
175_G184_T0.5650.25
108_Y141_L0.5640.25
28_G34_M0.5630.25
34_M42_Y0.5620.25
204_L209_G0.5600.25
153_V156_N0.5590.25
181_G190_S0.5580.25
183_G195_I0.5560.25
30_T42_Y0.5560.25
177_F184_T0.5490.24
56_R145_I0.5420.24
34_M37_Q0.5410.24
178_T183_G0.5400.24
174_P191_A0.5400.24
159_P164_I0.5390.24
141_L146_N0.5350.23
109_Y150_Q0.5330.23
74_E107_L0.5320.23
39_D48_I0.5300.23
163_L169_D0.5300.23
122_Y141_L0.5300.23
175_G182_H0.5290.23
205_I210_N0.5290.23
92_Q108_Y0.5280.23
189_E200_D0.5280.23
172_N187_S0.5270.23
203_Y210_N0.5200.23
58_L82_L0.5170.22
110_N150_Q0.5170.22
110_N125_Q0.5150.22
101_Y110_N0.5140.22
157_L201_L0.5140.22
197_T205_I0.5130.22
177_F185_P0.5120.22
62_L92_Q0.5090.22
133_G152_L0.5070.22
50_L53_C0.5030.22
71_W100_Q0.5030.22
95_R135_N0.5030.22
174_P186_T0.5020.22
176_V181_G0.5010.22
83_S87_P0.5010.22
71_W111_R0.5000.22
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4iglB 1 0.6438 100 0.381 Contact Map
4o9xA 1 0.6481 100 0.405 Contact Map
4iglA 1 0.3863 95.8 0.889 Contact Map
2mxwA 1 0.3734 47.9 0.938 Contact Map
3wknE 1 0.1631 26.1 0.946 Contact Map
4ro6A 1 0.3391 3.1 0.965 Contact Map
1r5mA 1 0.3777 2.7 0.966 Contact Map
4n04A 2 0.279 2.6 0.966 Contact Map
4z04A 2 0.206 2.5 0.967 Contact Map
1xrkA 2 0.2017 2.3 0.968 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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