GREMLIN Database
YIBG - Uncharacterized protein YibG
UniProt: P32106 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11763
Length: 153 (123)
Sequences: 2601 (2292)
Seq/√Len: 206.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
93_Q119_W2.8291.00
40_L43_E2.6831.00
112_N115_R2.5741.00
68_C81_L2.3071.00
60_S80_F2.2851.00
101_S120_M2.2511.00
124_V132_K2.1371.00
93_Q126_N2.1141.00
115_R118_Y2.1131.00
85_A93_Q2.0371.00
47_K51_K2.0251.00
76_K79_R1.8731.00
78_L96_Y1.7621.00
85_A124_V1.7571.00
77_Q81_L1.7541.00
97_G120_M1.7541.00
96_Y100_L1.7451.00
78_L82_E1.7341.00
117_I121_E1.7291.00
82_E121_E1.6541.00
73_N76_K1.6391.00
117_I135_L1.6231.00
142_K145_D1.6171.00
90_V123_A1.6081.00
135_L139_K1.5961.00
60_S87_Q1.5811.00
52_S60_S1.5801.00
64_Y81_L1.5731.00
61_F89_N1.5561.00
75_Y114_N1.5381.00
61_F95_N1.4991.00
81_L95_N1.4721.00
29_S32_G1.4621.00
93_Q132_K1.4421.00
116_A120_M1.4311.00
79_R118_Y1.3811.00
69_F72_N1.3741.00
63_L67_Y1.3701.00
45_L49_K1.3521.00
60_S132_K1.3371.00
121_E125_N1.3201.00
48_L62_R1.3121.00
82_E86_S1.2761.00
80_F119_W1.2731.00
76_K115_R1.2631.00
36_M41_S1.2321.00
32_G35_A1.2281.00
94_F134_K1.2181.00
35_A40_L1.2171.00
44_K48_L1.1951.00
64_Y77_Q1.1671.00
34_T38_Y1.1611.00
99_F138_L1.1521.00
120_M134_K1.1491.00
87_Q126_N1.1321.00
73_N112_N1.1191.00
97_G119_W1.1131.00
101_S134_K1.1021.00
123_A128_N1.0911.00
93_Q122_F1.0861.00
123_A131_A1.0751.00
66_Y138_L1.0741.00
56_D59_A1.0721.00
71_K110_Y1.0721.00
99_F105_P1.0701.00
49_K82_E1.0621.00
60_S93_Q1.0571.00
66_Y99_F1.0391.00
94_F131_A1.0261.00
89_N128_N1.0091.00
67_Y76_K1.0081.00
85_A92_A1.0041.00
52_S55_G1.0041.00
83_R122_F1.0031.00
78_L106_T1.0001.00
117_I138_L0.9971.00
64_Y80_F0.9881.00
94_F128_N0.9701.00
78_L117_I0.9661.00
114_N146_R0.9661.00
24_I27_N0.9490.99
45_L67_Y0.9370.99
103_T111_Y0.9200.99
32_G36_M0.9170.99
78_L100_L0.9100.99
61_F65_Q0.8860.99
82_E115_R0.8860.99
32_G48_L0.8660.99
69_F73_N0.8620.99
52_S59_A0.8620.99
101_S113_L0.8580.99
122_F125_N0.8560.99
95_N98_V0.8550.99
92_A131_A0.8500.99
128_N131_A0.8350.99
52_S80_F0.8210.98
45_L66_Y0.8210.98
32_G39_D0.8120.98
119_W122_F0.8120.98
88_G127_G0.8110.98
53_Q125_N0.8070.98
45_L63_L0.8060.98
76_K80_F0.7900.98
65_Q81_L0.7860.98
41_S44_K0.7740.98
61_F92_A0.7680.98
33_S37_T0.7550.97
35_A43_E0.7420.97
38_Y41_S0.7360.97
115_R119_W0.7360.97
78_L99_F0.7340.97
100_L106_T0.7300.97
90_V128_N0.7090.96
134_K137_E0.7090.96
68_C77_Q0.7030.96
51_K56_D0.6940.96
74_I113_L0.6910.96
68_C74_I0.6900.95
52_S124_V0.6840.95
60_S83_R0.6780.95
97_G116_A0.6750.95
49_K53_Q0.6700.95
84_S123_A0.6630.94
60_S85_A0.6550.94
80_F83_R0.6520.94
98_V120_M0.6510.94
32_G44_K0.6450.94
33_S36_M0.6420.93
118_Y122_F0.6380.93
91_T128_N0.6360.93
121_E139_K0.6310.93
79_R82_E0.6240.92
138_L142_K0.6230.92
64_Y84_S0.6190.92
119_W123_A0.6190.92
69_F77_Q0.6130.92
21_D25_K0.6100.92
28_E32_G0.6090.92
42_E114_N0.6080.91
101_S116_A0.6030.91
74_I104_N0.5980.91
137_E140_K0.5950.91
43_E46_M0.5910.90
75_Y146_R0.5880.90
49_K63_L0.5840.90
43_E115_R0.5830.90
72_N111_Y0.5810.90
57_S89_N0.5800.89
29_S33_S0.5790.89
65_Q68_C0.5650.88
98_V101_S0.5650.88
31_M35_A0.5570.87
34_T37_T0.5560.87
65_Q137_E0.5560.87
97_G123_A0.5540.87
86_S125_N0.5490.87
55_G87_Q0.5490.87
52_S85_A0.5480.87
94_F133_S0.5460.86
96_Y119_W0.5460.86
23_K26_Q0.5450.86
94_F130_D0.5450.86
75_Y110_Y0.5410.86
139_K142_K0.5400.86
30_M33_S0.5360.85
103_T112_N0.5330.85
30_M34_T0.5320.85
47_K119_W0.5310.85
32_G51_K0.5290.85
79_R83_R0.5290.85
44_K51_K0.5230.84
62_R65_Q0.5220.84
21_D33_S0.5180.83
95_N134_K0.5170.83
47_K80_F0.5100.83
122_F126_N0.5090.82
23_K27_N0.5070.82
42_E75_Y0.5050.82
31_M34_T0.5030.82
84_S92_A0.5030.82
59_A63_L0.5020.82
96_Y135_L0.5020.82
48_L51_K0.5010.81
28_E31_M0.5000.81
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4bwrA 1 0.915 99.6 0.42 Contact Map
1ouvA 1 0.8235 99.6 0.421 Contact Map
1klxA 1 0.7516 99.6 0.455 Contact Map
3e4bA 1 0.7516 99.2 0.545 Contact Map
3rjvA 1 0.902 99.1 0.567 Contact Map
1hh8A 1 0.8105 99 0.585 Contact Map
4gywA 2 0.8105 98.9 0.596 Contact Map
3urzA 1 0.8039 98.9 0.601 Contact Map
4i2zA 1 0.8105 98.9 0.605 Contact Map
1xnfA 2 0.7974 98.9 0.606 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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