YDDB - ECOLI - GREMLIN Contacts

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YDDB - Uncharacterized protein YddB

UniProt:	P31827	Sequences: MKRVLIPGVILCGADVAQAVDDKNMYMHFFEEMTVYAPVPVPVNGNTHYTSESIERLPTGNGNISDLLRTNPAVRMDSTQSTSLNQGDIRPEKISIHGASPYQNAYLIDGISATNNLNPANESDASSATNISGMSQGYYLDVSLLDNVTLYDSFVPVEFGRFNGGVIDAKIKRFNADDSKVKLGYRTTRSDWLTSHIDENNKSAFNQGSSGSTYYSPDFKKNFYTLSFNQELADNFGVTAGLSRRQSDITRADYVSNDGIVAGRAQYKNVIDTALSKFTWFASDRFTHDLTLKYTGSSRDYNTSTFPQSDREMGNKSYGLAWDMDTQLAWAKLRTTVGWDHISDYTRHDHDIWYTELSCTYGDITGRCTRGGLGHISQAVDNYTFKTRLDWQKFAVGNVSHQPYFGAEYIYSDAWTERHNQSESYVINAAGKKTNHTIYHKGKGRLGIDNYTLYMADRISWRNVSLMPGVRYDYDNYLSNHNISPRFMTEWDIFANQTSMITAGYNRYYGGNILDMGLRDIRNSWTESVSGNKTLTRYQDLKTPYNDELAMGLQQKIGKNVIARANYVYREAHDQISKSSRTDSATKTTITEYNNDGKTKTHSFSLSFELAEPLHIRQVDINPQIVFSYIKSKGNLSLNNGYEESNTGDNQVVYNGNLVSYDSVPVADFNNPLKISLNMDFTHQPSGLVWANTLAWQEARKARIILGKTNAQYISEYSDYKQYVDEKLDSSLTWDTRLSWTPQFLQQQNLTISADILNVLDSKTAVDTTNTGVATYASGRTFWLDVSMKF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11743
Length:	790 (630)
Sequences:	46291 (38223)
Seq/√Len:	1522.8

ECOLI - YDDB CIRA YNCD FEPA FHUA BTUB FHUE FECA FIU

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
627_F	673_L	4.262	1.00
236_F	280_W	3.857	1.00
470_V	483_I	3.708	1.00
569_Y	602_H	3.509	1.00
286_F	326_T	3.463	1.00
505_Y	547_D	3.416	1.00
694_L	732_L	3.291	1.00
507_R	547_D	3.272	1.00
499_S	553_L	3.231	1.00
753_S	785_D	3.175	1.00
472_Y	483_I	3.063	1.00
689_V	739_S	3.021	1.00
244_R	272_D	2.911	1.00
289_D	323_D	2.847	1.00
401_H	457_D	2.829	1.00
242_L	272_D	2.774	1.00
624_Q	678_N	2.762	1.00
600_K	635_N	2.676	1.00
183_L	224_Y	2.568	1.00
499_S	555_Q	2.568	1.00
286_F	324_M	2.565	1.00
287_T	325_D	2.542	1.00
472_Y	481_H	2.484	1.00
561_V	610_L	2.477	1.00
285_R	326_T	2.450	1.00
294_Y	318_Y	2.412	1.00
569_Y	600_K	2.397	1.00
621_I	679_M	2.381	1.00
464_V	491_W	2.365	1.00
555_Q	563_A	2.356	1.00
734_W	760_L	2.345	1.00
147_N	170_K	2.325	1.00
292_L	318_Y	2.309	1.00
51_S	55_E	2.302	1.00
230_Q	238_V	2.270	1.00
478_L	481_H	2.230	1.00
185_Y	224_Y	2.229	1.00
756_I	759_V	2.211	1.00
246_Q	270_V	2.195	1.00
145_L	169_A	2.182	1.00
236_F	278_F	2.181	1.00
50_T	53_S	2.175	1.00
283_S	286_F	2.171	1.00
629_Y	673_L	2.144	1.00
296_G	316_K	2.092	1.00
755_D	783_W	2.038	1.00
240_A	276_S	2.017	1.00
400_S	462_R	1.974	1.00
562_I	609_E	1.958	1.00
739_S	751_T	1.954	1.00
335_T	387_T	1.950	1.00
237_G	279_T	1.950	1.00
622_N	680_D	1.940	1.00
288_H	324_M	1.931	1.00
568_V	630_I	1.916	1.00
751_T	787_S	1.907	1.00
493_I	501_I	1.906	1.00
406_G	454_Y	1.901	1.00
411_Y	449_D	1.897	1.00
330_W	391_W	1.889	1.00
696_W	732_L	1.882	1.00
493_I	499_S	1.881	1.00
292_L	320_L	1.871	1.00
507_R	545_Y	1.868	1.00
699_A	727_K	1.868	1.00
108_I	113_A	1.856	1.00
564_R	607_S	1.850	1.00
691_A	737_R	1.848	1.00
333_L	387_T	1.815	1.00
750_L	788_M	1.809	1.00
567_Y	602_H	1.804	1.00
741_T	751_T	1.800	1.00
505_Y	549_L	1.798	1.00
337_V	383_Y	1.797	1.00
184_G	225_T	1.788	1.00
675_I	696_W	1.785	1.00
563_A	608_F	1.774	1.00
494_F	498_T	1.772	1.00
335_T	385_F	1.772	1.00
181_V	228_F	1.768	1.00
490_E	500_M	1.762	1.00
63_N	66_D	1.761	1.00
754_A	782_F	1.753	1.00
609_E	624_Q	1.730	1.00
623_P	679_M	1.728	1.00
694_L	734_W	1.720	1.00
547_D	573_H	1.713	1.00
492_D	498_T	1.713	1.00
407_A	451_Y	1.712	1.00
48_H	149_T	1.709	1.00
565_A	606_L	1.698	1.00
571_E	598_K	1.684	1.00
279_T	287_T	1.682	1.00
401_H	459_I	1.678	1.00
464_V	489_T	1.676	1.00
571_E	600_K	1.664	1.00
578_K	593_Y	1.664	1.00
579_S	594_N	1.662	1.00
485_P	507_R	1.653	1.00
325_D	332_K	1.652	1.00
325_D	334_R	1.652	1.00
465_S	492_D	1.646	1.00
281_F	287_T	1.645	1.00
109_D	277_K	1.641	1.00
71_N	150_L	1.638	1.00
243_S	273_T	1.635	1.00
238_V	278_F	1.625	1.00
396_V	399_V	1.618	1.00
688_L	740_W	1.612	1.00
542_K	574_D	1.612	1.00
235_N	280_W	1.611	1.00
333_L	389_L	1.602	1.00
548_E	570_R	1.598	1.00
146_D	172_K	1.591	1.00
692_N	734_W	1.591	1.00
623_P	677_L	1.591	1.00
613_P	620_D	1.590	1.00
575_Q	599_T	1.587	1.00
290_L	320_L	1.582	1.00
184_G	787_S	1.578	1.00
621_I	681_F	1.570	1.00
182_K	789_K	1.567	1.00
279_T	289_D	1.558	1.00
554_Q	564_R	1.553	1.00
52_E	56_R	1.552	1.00
402_Q	460_S	1.548	1.00
334_R	388_R	1.543	1.00
696_W	730_S	1.538	1.00
187_T	220_K	1.525	1.00
240_A	274_A	1.523	1.00
598_K	636_L	1.522	1.00
545_Y	574_D	1.516	1.00
331_A	391_W	1.514	1.00
744_F	748_Q	1.506	1.00
337_V	385_F	1.504	1.00
149_T	168_D	1.501	1.00
96_I	165_G	1.501	1.00
51_S	172_K	1.497	1.00
339_W	383_Y	1.494	1.00
602_H	631_K	1.490	1.00
409_Y	451_Y	1.487	1.00
693_T	735_D	1.487	1.00
750_L	786_V	1.485	1.00
620_D	681_F	1.478	1.00
452_T	473_D	1.475	1.00
39_V	42_P	1.468	1.00
756_I	782_F	1.465	1.00
501_I	553_L	1.463	1.00
565_A	604_F	1.461	1.00
612_E	623_P	1.460	1.00
764_T	777_A	1.454	1.00
742_P	752_I	1.451	1.00
619_V	681_F	1.450	1.00
613_P	619_V	1.448	1.00
494_F	499_S	1.436	1.00
460_S	465_S	1.431	1.00
108_I	171_I	1.426	1.00
146_D	173_R	1.422	1.00
411_Y	447_G	1.420	1.00
626_V	676_S	1.411	1.00
701_K	727_K	1.408	1.00
502_T	554_Q	1.404	1.00
510_G	544_P	1.403	1.00
465_S	490_E	1.397	1.00
689_V	741_T	1.395	1.00
287_T	327_Q	1.394	1.00
561_V	608_F	1.391	1.00
736_T	759_V	1.389	1.00
52_E	55_E	1.385	1.00
556_K	562_I	1.380	1.00
244_R	270_V	1.379	1.00
568_V	603_S	1.378	1.00
53_S	56_R	1.374	1.00
294_Y	316_K	1.372	1.00
752_I	786_V	1.371	1.00
502_T	566_N	1.371	1.00
625_I	677_L	1.368	1.00
488_M	504_G	1.367	1.00
466_L	489_T	1.367	1.00
485_P	489_T	1.366	1.00
577_S	596_D	1.366	1.00
97_H	605_S	1.363	1.00
242_L	274_A	1.361	1.00
237_G	281_F	1.361	1.00
238_V	242_L	1.360	1.00
550_A	566_N	1.358	1.00
327_Q	332_K	1.356	1.00
502_T	552_G	1.355	1.00
750_L	754_A	1.352	1.00
173_R	277_K	1.350	1.00
628_S	674_K	1.349	1.00
186_R	223_F	1.349	1.00
141_D	144_L	1.344	1.00
331_A	389_L	1.342	1.00
689_V	751_T	1.334	1.00
690_W	738_L	1.329	1.00
678_N	693_T	1.327	1.00
288_H	322_W	1.321	1.00
181_V	185_Y	1.320	1.00
551_M	567_Y	1.317	1.00
177_D	237_G	1.316	1.00
695_A	735_D	1.315	1.00
227_S	239_T	1.314	1.00
173_R	279_T	1.314	1.00
285_R	327_Q	1.310	1.00
673_L	698_E	1.310	1.00
482_N	545_Y	1.308	1.00
73_A	628_S	1.305	1.00
503_A	549_L	1.303	1.00
188_T	221_K	1.303	1.00
452_T	471_R	1.297	1.00
109_D	291_T	1.297	1.00
328_L	333_L	1.290	1.00
680_D	691_A	1.288	1.00
620_D	682_T	1.287	1.00
604_F	629_Y	1.286	1.00
341_H	381_D	1.286	1.00
737_R	753_S	1.283	1.00
743_Q	749_N	1.279	1.00
328_L	389_L	1.278	1.00
495_A	498_T	1.276	1.00
700_R	728_L	1.272	1.00
290_L	322_W	1.270	1.00
683_H	686_S	1.266	1.00
182_K	787_S	1.264	1.00
492_D	495_A	1.264	1.00
282_A	288_H	1.263	1.00
460_S	463_N	1.263	1.00
187_T	222_N	1.260	1.00
468_P	487_F	1.259	1.00
456_A	467_M	1.257	1.00
503_A	551_M	1.256	1.00
756_I	780_R	1.256	1.00
179_S	228_F	1.251	1.00
388_R	454_Y	1.249	1.00
735_D	757_L	1.248	1.00
611_A	622_N	1.248	1.00
238_V	276_S	1.246	1.00
552_G	566_N	1.233	1.00
549_L	571_E	1.227	1.00
72_P	607_S	1.226	1.00
338_G	384_T	1.225	1.00
567_Y	604_F	1.218	1.00
458_R	467_M	1.205	1.00
613_P	621_I	1.203	1.00
185_Y	222_N	1.201	1.00
688_L	738_L	1.200	1.00
499_S	503_A	1.199	1.00
186_R	785_D	1.198	1.00
687_G	740_W	1.186	1.00
563_A	606_L	1.183	1.00
239_T	277_K	1.183	1.00
47_T	152_D	1.177	1.00
180_K	229_N	1.177	1.00
402_Q	458_R	1.175	1.00
679_M	692_N	1.175	1.00
473_D	484_S	1.174	1.00
408_E	452_T	1.172	1.00
74_V	96_I	1.170	1.00
702_A	728_L	1.165	1.00
386_K	408_E	1.164	1.00
296_G	314_G	1.163	1.00
549_L	569_Y	1.162	1.00
29_F	32_E	1.157	1.00
742_P	750_L	1.155	1.00
784_L	788_M	1.152	1.00
474_Y	481_H	1.152	1.00
291_T	321_A	1.151	1.00
754_A	784_L	1.148	1.00
332_K	390_D	1.145	1.00
182_K	227_S	1.145	1.00
622_N	682_T	1.144	1.00
66_D	69_R	1.140	1.00
109_D	171_I	1.139	1.00
274_A	294_Y	1.137	1.00
323_D	334_R	1.135	1.00
612_E	679_M	1.134	1.00
739_S	753_S	1.130	1.00
111_I	338_G	1.126	1.00
697_Q	700_R	1.125	1.00
601_T	632_S	1.125	1.00
289_D	325_D	1.123	1.00
751_T	789_K	1.117	1.00
733_T	762_S	1.111	1.00
573_H	598_K	1.111	1.00
395_A	398_N	1.109	1.00
629_Y	672_P	1.108	1.00
757_L	781_T	1.106	1.00
493_I	553_L	1.105	1.00
560_N	612_E	1.102	1.00
489_T	493_I	1.102	1.00
692_N	736_T	1.102	1.00
489_T	503_A	1.096	1.00
609_E	622_N	1.092	1.00
334_R	390_D	1.081	1.00
341_H	379_A	1.080	1.00
97_H	550_A	1.073	1.00
546_N	570_R	1.070	1.00
107_L	112_S	1.066	1.00
183_L	187_T	1.063	1.00
409_Y	449_D	1.060	1.00
179_S	230_Q	1.059	1.00
144_L	241_G	1.057	1.00
560_N	610_L	1.057	1.00
235_N	282_A	1.051	1.00
281_F	284_D	1.049	1.00
26_Y	29_F	1.046	1.00
75_R	674_K	1.045	1.00
30_F	33_M	1.044	1.00
553_L	565_A	1.043	1.00
453_L	472_Y	1.043	1.00
179_S	183_L	1.043	1.00
400_S	459_I	1.041	1.00
675_I	698_E	1.040	1.00
241_G	275_L	1.039	1.00
467_M	488_M	1.038	1.00
466_L	487_F	1.038	1.00
20_V	23_K	1.036	1.00
407_A	453_L	1.033	1.00
666_V	701_K	1.027	1.00
150_L	167_I	1.027	1.00
571_E	635_N	1.025	1.00
744_F	749_N	1.025	1.00
401_H	406_G	1.023	1.00
282_A	324_M	1.022	1.00
51_S	146_D	1.021	1.00
183_L	226_L	1.020	1.00
568_V	628_S	1.020	1.00
152_D	605_S	1.017	1.00
298_S	314_G	1.017	1.00
508_Y	546_N	1.013	1.00
752_I	784_L	1.010	1.00
484_S	509_Y	1.010	1.00
408_E	454_Y	1.010	1.00
141_D	243_S	1.008	1.00
163_N	546_N	1.005	1.00
293_K	319_G	1.002	1.00
680_D	689_V	1.002	1.00
177_D	234_D	1.001	1.00
71_N	74_V	1.001	1.00
558_G	561_V	1.000	1.00
149_T	170_K	1.000	1.00
568_V	605_S	0.998	1.00
336_T	386_K	0.993	1.00
323_D	336_T	0.993	1.00
48_H	147_N	0.992	1.00
107_L	166_V	0.990	1.00
399_V	459_I	0.988	1.00
598_K	635_N	0.985	1.00
683_H	690_W	0.983	1.00
57_L	70_T	0.979	1.00
19_A	23_K	0.976	1.00
451_Y	474_Y	0.969	1.00
694_L	733_T	0.969	1.00
630_I	670_N	0.967	1.00
682_T	689_V	0.963	1.00
54_I	67_L	0.963	1.00
546_N	572_A	0.962	1.00
612_E	621_I	0.962	1.00
563_A	567_Y	0.961	1.00
339_W	381_D	0.961	1.00
146_D	170_K	0.958	1.00
179_S	238_V	0.957	1.00
233_A	236_F	0.956	1.00
557_I	563_A	0.956	1.00
268_K	300_D	0.956	1.00
222_N	246_Q	0.955	1.00
741_T	789_K	0.952	1.00
144_L	275_L	0.952	1.00
738_L	756_I	0.948	1.00
405_F	455_M	0.947	1.00
43_V	488_M	0.946	1.00
599_T	667_A	0.945	1.00
498_T	555_Q	0.944	1.00
458_R	465_S	0.944	1.00
492_D	500_M	0.943	1.00
403_P	457_D	0.940	1.00
501_I	551_M	0.939	1.00
47_T	607_S	0.937	1.00
737_R	755_D	0.936	1.00
94_I	106_Y	0.936	1.00
448_I	477_Y	0.931	1.00
610_L	623_P	0.931	1.00
625_I	675_I	0.931	1.00
106_Y	167_I	0.927	1.00
282_A	286_F	0.927	1.00
112_S	161_R	0.925	1.00
277_K	289_D	0.923	1.00
510_G	516_M	0.922	1.00
317_S	340_D	0.922	1.00
469_G	486_R	0.916	1.00
743_Q	750_L	0.912	1.00
733_T	760_L	0.911	1.00
474_Y	479_S	0.910	1.00
72_P	626_V	0.909	1.00
733_T	764_T	0.907	1.00
180_K	789_K	0.905	1.00
225_T	243_S	0.904	1.00
565_A	569_Y	0.904	1.00
475_D	511_G	0.903	1.00
18_Q	21_D	0.903	1.00
144_L	239_T	0.898	1.00
105_A	112_S	0.897	1.00
386_K	410_I	0.893	1.00
283_S	326_T	0.892	1.00
753_S	787_S	0.891	1.00
107_L	168_D	0.891	1.00
461_W	466_L	0.890	1.00
733_T	777_A	0.889	1.00
159_F	166_V	0.889	1.00
184_G	785_D	0.888	1.00
487_F	505_Y	0.888	1.00
459_I	468_P	0.888	1.00
288_H	292_L	0.888	1.00
17_A	20_V	0.887	1.00
235_N	281_F	0.887	1.00
545_Y	573_H	0.886	1.00
485_P	505_Y	0.886	1.00
736_T	756_I	0.880	1.00
157_V	469_G	0.880	1.00
516_M	593_Y	0.877	1.00
387_T	391_W	0.876	1.00
759_V	780_R	0.869	1.00
46_N	149_T	0.868	1.00
749_N	789_K	0.866	1.00
224_Y	228_F	0.866	1.00
627_F	675_I	0.865	1.00
94_I	167_I	0.863	1.00
246_Q	268_K	0.860	1.00
406_G	410_I	0.860	1.00
23_K	26_Y	0.860	1.00
557_I	561_V	0.860	1.00
547_D	571_E	0.858	1.00
695_A	733_T	0.857	1.00
634_G	637_S	0.857	1.00
183_L	788_M	0.856	1.00
56_R	680_D	0.855	1.00
224_Y	244_R	0.854	1.00
470_V	485_P	0.852	1.00
482_N	509_Y	0.852	1.00
560_N	611_A	0.852	1.00
96_I	150_L	0.848	1.00
111_I	336_T	0.846	1.00
694_L	731_S	0.846	1.00
748_Q	788_M	0.843	1.00
223_F	243_S	0.842	1.00
328_L	331_A	0.842	1.00
30_F	34_T	0.841	1.00
187_T	191_D	0.841	1.00
223_F	245_R	0.840	1.00
73_A	152_D	0.840	1.00
173_R	289_D	0.839	1.00
97_H	568_V	0.838	1.00
43_V	490_E	0.838	1.00
415_W	445_R	0.838	1.00
726_E	766_V	0.837	1.00
290_L	294_Y	0.835	1.00
176_A	180_K	0.835	1.00
752_I	756_I	0.833	1.00
666_V	672_P	0.829	1.00
236_F	282_A	0.829	1.00
461_W	489_T	0.826	1.00
399_V	406_G	0.826	1.00
453_L	474_Y	0.825	1.00
761_D	779_G	0.824	1.00
64_I	169_A	0.824	1.00
734_W	759_V	0.824	1.00
49_Y	71_N	0.823	1.00
600_K	633_K	0.821	1.00
500_M	554_Q	0.821	1.00
608_F	625_I	0.819	1.00
275_L	293_K	0.819	1.00
413_D	447_G	0.818	1.00
231_E	237_G	0.815	1.00
51_S	54_I	0.814	1.00
549_L	553_L	0.814	1.00
456_A	486_R	0.812	1.00
59_T	67_L	0.811	1.00
498_T	556_K	0.811	1.00
182_K	185_Y	0.809	1.00
405_F	409_Y	0.809	1.00
143_S	225_T	0.808	1.00
697_Q	731_S	0.807	1.00
142_V	145_L	0.807	1.00
158_E	404_Y	0.807	1.00
398_N	401_H	0.807	1.00
455_M	470_V	0.806	1.00
60_G	66_D	0.805	1.00
151_Y	159_F	0.804	1.00
148_V	169_A	0.804	1.00
181_V	226_L	0.803	1.00
682_T	741_T	0.803	1.00
544_P	572_A	0.802	1.00
610_L	613_P	0.800	1.00
45_G	550_A	0.795	1.00
47_T	71_N	0.793	1.00
245_R	271_I	0.793	1.00
578_K	591_T	0.793	1.00
111_I	321_A	0.791	1.00
400_S	460_S	0.791	1.00
333_L	337_V	0.791	1.00
176_A	229_N	0.791	1.00
226_L	230_Q	0.789	1.00
404_Y	458_R	0.786	1.00
22_D	25_M	0.785	1.00
607_S	624_Q	0.785	1.00
555_Q	558_G	0.784	1.00
673_L	696_W	0.783	1.00
401_H	404_Y	0.781	1.00
687_G	741_T	0.781	1.00
105_A	162_F	0.781	1.00
106_Y	137_G	0.780	1.00
320_L	339_W	0.779	1.00
384_T	388_R	0.778	1.00
757_L	783_W	0.778	1.00
704_I	726_E	0.778	1.00
749_N	788_M	0.778	1.00
28_H	31_E	0.775	1.00
326_T	329_A	0.774	1.00
221_K	247_S	0.772	1.00
97_H	603_S	0.771	1.00
188_T	783_W	0.771	1.00
231_E	234_D	0.770	1.00
229_N	239_T	0.770	1.00
395_A	400_S	0.770	1.00
179_S	231_E	0.768	1.00
161_R	450_N	0.767	1.00
396_V	401_H	0.763	1.00
690_W	736_T	0.761	1.00
485_P	488_M	0.760	1.00
186_R	783_W	0.760	1.00
395_A	399_V	0.759	1.00
732_L	762_S	0.758	1.00
450_N	511_G	0.758	1.00
516_M	519_R	0.755	1.00
741_T	749_N	0.755	1.00
672_P	698_E	0.752	1.00
631_K	672_P	0.751	1.00
449_D	476_N	0.750	1.00
422_S	425_Y	0.750	1.00
227_S	241_G	0.749	1.00
76_M	94_I	0.749	1.00
675_I	679_M	0.747	1.00
513_I	516_M	0.744	1.00
285_R	328_L	0.742	1.00
517_G	520_D	0.742	1.00
272_D	296_G	0.742	1.00
678_N	691_A	0.740	1.00
413_D	445_R	0.739	1.00
240_A	244_R	0.739	1.00
321_A	338_G	0.739	1.00
453_L	457_D	0.737	1.00
272_D	276_S	0.737	1.00
572_A	575_Q	0.735	1.00
47_T	72_P	0.734	1.00
105_A	166_V	0.734	1.00
579_S	582_T	0.731	1.00
270_V	298_S	0.731	1.00
180_K	748_Q	0.730	1.00
729_D	762_S	0.730	1.00
280_W	283_S	0.729	1.00
173_R	291_T	0.729	1.00
682_T	687_G	0.728	1.00
28_H	33_M	0.728	1.00
760_L	763_K	0.727	1.00
64_I	145_L	0.726	1.00
761_D	780_R	0.726	1.00
580_S	591_T	0.726	1.00
683_H	688_L	0.726	1.00
461_W	464_V	0.723	1.00
695_A	734_W	0.723	1.00
544_P	575_Q	0.720	1.00
484_S	507_R	0.719	1.00
624_Q	680_D	0.717	1.00
64_I	67_L	0.717	1.00
672_P	699_A	0.717	1.00
143_S	184_G	0.715	1.00
403_P	455_M	0.714	1.00
513_I	541_L	0.714	1.00
606_L	610_L	0.714	1.00
572_A	599_T	0.713	1.00
220_K	248_D	0.713	1.00
570_R	601_T	0.713	1.00
562_I	611_A	0.712	1.00
622_N	625_I	0.710	1.00
274_A	278_F	0.710	1.00
404_Y	408_E	0.709	1.00
186_R	753_S	0.708	1.00
246_Q	272_D	0.708	1.00
236_F	276_S	0.704	1.00
269_N	297_S	0.704	1.00
178_D	181_V	0.703	1.00
397_G	400_S	0.703	1.00
324_M	335_T	0.702	1.00
457_D	468_P	0.702	1.00
694_L	760_L	0.701	1.00
56_R	689_V	0.701	1.00
276_S	280_W	0.700	1.00
601_T	630_I	0.698	1.00
21_D	24_N	0.698	1.00
237_G	287_T	0.697	1.00
467_M	490_E	0.696	1.00
298_S	312_E	0.696	1.00
604_F	608_F	0.696	1.00
110_G	168_D	0.695	1.00
432_K	435_N	0.695	1.00
239_T	275_L	0.694	1.00
689_V	692_N	0.693	1.00
55_E	787_S	0.693	1.00
143_S	182_K	0.693	1.00
45_G	566_N	0.692	1.00
154_F	508_Y	0.691	1.00
190_S	247_S	0.691	1.00
235_N	283_S	0.691	1.00
28_H	32_E	0.689	1.00
516_M	520_D	0.689	1.00
701_K	706_L	0.687	1.00
277_K	291_T	0.687	1.00
190_S	221_K	0.686	1.00
606_L	627_F	0.686	1.00
318_Y	341_H	0.686	1.00
382_N	412_S	0.685	1.00
297_S	315_N	0.684	1.00
331_A	405_F	0.682	1.00
699_A	730_S	0.681	1.00
74_V	94_I	0.679	1.00
106_Y	169_A	0.679	1.00
385_F	389_L	0.678	1.00
404_Y	456_A	0.678	1.00
172_K	227_S	0.678	1.00
401_H	408_E	0.678	1.00
408_E	411_Y	0.677	1.00
399_V	408_E	0.672	1.00
401_H	405_F	0.671	1.00
153_S	550_A	0.671	1.00
561_V	565_A	0.671	1.00
605_S	628_S	0.671	1.00
318_Y	322_W	0.669	1.00
26_Y	30_F	0.669	1.00
151_Y	166_V	0.669	1.00
755_D	785_D	0.668	1.00
733_T	759_V	0.667	1.00
450_N	475_D	0.666	1.00
343_S	379_A	0.666	1.00
249_I	267_Y	0.664	1.00
17_A	21_D	0.664	1.00
385_F	409_Y	0.660	1.00
391_W	403_P	0.659	1.00
494_F	555_Q	0.659	1.00
612_E	619_V	0.658	1.00
681_F	690_W	0.658	1.00
146_D	176_A	0.658	1.00
542_K	545_Y	0.658	1.00
463_N	495_A	0.657	1.00
778_S	781_T	0.657	1.00
557_I	560_N	0.655	1.00
486_R	504_G	0.654	1.00
25_M	28_H	0.653	1.00
177_D	281_F	0.652	1.00
177_D	231_E	0.652	1.00
686_S	740_W	0.649	1.00
347_R	375_H	0.648	1.00
279_T	282_A	0.646	1.00
665_P	706_L	0.645	1.00
72_P	152_D	0.644	1.00
632_S	670_N	0.644	1.00
553_L	563_A	0.641	1.00
43_V	467_M	0.640	1.00
289_D	334_R	0.639	1.00
454_Y	471_R	0.636	1.00
188_T	191_D	0.635	1.00
69_R	695_A	0.634	1.00
502_T	564_R	0.634	1.00
179_S	182_K	0.632	1.00
468_P	489_T	0.632	1.00
620_D	683_H	0.630	1.00
157_V	456_A	0.630	1.00
151_Y	155_V	0.630	1.00
326_T	333_L	0.629	1.00
152_D	607_S	0.629	1.00
331_A	403_P	0.628	1.00
619_V	623_P	0.628	1.00
234_D	238_V	0.627	1.00
431_G	434_T	0.627	1.00
154_F	506_N	0.627	1.00
679_M	683_H	0.626	1.00
41_V	492_D	0.625	1.00
179_S	185_Y	0.625	1.00
740_W	743_Q	0.625	1.00
698_E	731_S	0.624	1.00
482_N	543_T	0.624	1.00
576_I	593_Y	0.621	1.00
662_D	665_P	0.621	1.00
513_I	517_G	0.621	1.00
226_L	242_L	0.621	1.00
668_D	701_K	0.620	1.00
236_F	240_A	0.619	1.00
137_G	169_A	0.618	1.00
482_N	507_R	0.618	1.00
633_K	664_V	0.618	1.00
345_Y	377_S	0.616	1.00
608_F	612_E	0.616	1.00
391_W	405_F	0.616	1.00
465_S	468_P	0.616	1.00
250_T	263_G	0.616	1.00
665_P	701_K	0.615	1.00
173_R	287_T	0.614	1.00
683_H	687_G	0.614	1.00
53_S	57_L	0.614	1.00
784_L	787_S	0.614	1.00
743_Q	748_Q	0.614	1.00
751_T	754_A	0.614	1.00
170_K	173_R	0.613	1.00
541_L	576_I	0.613	1.00
632_S	667_A	0.613	1.00
56_R	682_T	0.613	1.00
410_I	450_N	0.612	1.00
59_T	70_T	0.611	1.00
175_N	238_V	0.610	1.00
448_I	511_G	0.610	1.00
508_Y	548_E	0.610	1.00
599_T	632_S	0.610	1.00
549_L	567_Y	0.610	1.00
186_R	755_D	0.609	1.00
402_Q	405_F	0.609	1.00
189_R	782_F	0.609	1.00
67_L	142_V	0.606	1.00
391_W	396_V	0.606	1.00
600_K	631_K	0.605	1.00
411_Y	451_Y	0.604	1.00
698_E	730_S	0.603	1.00
75_R	671_N	0.603	1.00
406_G	411_Y	0.603	1.00
31_E	34_T	0.602	1.00
463_N	491_W	0.602	1.00
285_R	329_A	0.600	1.00
558_G	610_L	0.599	1.00
113_A	319_G	0.599	1.00
398_N	403_P	0.598	1.00
190_S	781_T	0.598	1.00
396_V	403_P	0.598	1.00
687_G	743_Q	0.597	1.00
158_E	454_Y	0.597	1.00
630_I	674_K	0.597	1.00
390_D	404_Y	0.596	1.00
383_Y	411_Y	0.595	1.00
18_Q	23_K	0.595	1.00
736_T	754_A	0.595	1.00
462_R	495_A	0.594	1.00
555_Q	564_R	0.593	1.00
185_Y	188_T	0.593	1.00
388_R	406_G	0.592	1.00
228_F	238_V	0.591	1.00
95_S	103_Q	0.590	1.00
574_D	595_N	0.590	1.00
175_N	279_T	0.590	1.00
333_L	385_F	0.589	1.00
576_I	595_N	0.589	1.00
175_N	237_G	0.588	1.00
391_W	395_A	0.588	1.00
611_A	620_D	0.587	1.00
623_P	627_F	0.586	1.00
786_V	790_F	0.586	1.00
189_R	220_K	0.585	1.00
24_N	27_M	0.585	1.00
493_I	498_T	0.584	1.00
639_N	642_Y	0.584	1.00
538_Y	594_N	0.583	1.00
185_Y	189_R	0.580	1.00
607_S	626_V	0.579	1.00
383_Y	387_T	0.579	1.00
228_F	231_E	0.578	1.00
551_M	555_Q	0.578	1.00
235_N	284_D	0.578	1.00
389_L	405_F	0.577	1.00
43_V	46_N	0.577	1.00
66_D	757_L	0.576	1.00
400_S	461_W	0.576	1.00
541_L	595_N	0.574	1.00
623_P	626_V	0.572	1.00
187_T	784_L	0.572	1.00
404_Y	407_A	0.571	1.00
514_L	517_G	0.570	1.00
557_I	608_F	0.570	1.00
172_K	239_T	0.570	1.00
562_I	565_A	0.569	1.00
625_I	629_Y	0.569	1.00
175_N	239_T	0.568	1.00
248_D	268_K	0.568	1.00
324_M	328_L	0.567	1.00
503_A	553_L	0.567	1.00
103_Q	544_P	0.567	1.00
384_T	408_E	0.567	1.00
176_A	237_G	0.567	1.00
692_N	759_V	0.567	1.00
221_K	245_R	0.565	1.00
191_D	780_R	0.565	1.00
547_D	569_Y	0.565	1.00
381_D	413_D	0.565	1.00
384_T	387_T	0.565	1.00
675_I	732_L	0.565	1.00
612_E	620_D	0.564	1.00
630_I	634_G	0.564	1.00
191_D	782_F	0.563	1.00
238_V	241_G	0.563	1.00
336_T	388_R	0.563	1.00
45_G	152_D	0.561	1.00
181_V	189_R	0.561	1.00
509_Y	543_T	0.560	1.00
509_Y	545_Y	0.560	1.00
29_F	33_M	0.559	1.00
674_K	697_Q	0.559	1.00
480_N	543_T	0.559	1.00
567_Y	629_Y	0.559	1.00
459_I	466_L	0.558	1.00
276_S	292_L	0.558	1.00
316_K	343_S	0.557	1.00
732_L	760_L	0.557	1.00
72_P	75_R	0.557	1.00
468_P	485_P	0.556	1.00
395_A	402_Q	0.556	1.00
742_P	786_V	0.556	1.00
741_T	744_F	0.556	1.00
491_W	494_F	0.554	1.00
677_L	694_L	0.553	1.00
550_A	605_S	0.553	1.00
675_I	731_S	0.552	1.00
112_S	384_T	0.552	1.00
782_F	786_V	0.551	1.00
671_N	697_Q	0.550	1.00
365_T	368_C	0.550	1.00
610_L	621_I	0.549	1.00
575_Q	597_G	0.549	1.00
271_I	297_S	0.548	1.00
668_D	672_P	0.548	1.00
487_F	490_E	0.548	1.00
466_L	470_V	0.548	1.00
544_P	574_D	0.546	1.00
703_R	707_G	0.546	1.00
286_F	328_L	0.545	1.00
388_R	408_E	0.544	1.00
398_N	462_R	0.544	1.00
278_F	290_L	0.544	1.00
754_A	785_D	0.544	1.00
499_S	557_I	0.544	1.00
368_C	371_G	0.544	1.00
738_L	754_A	0.543	1.00
321_A	336_T	0.543	1.00
107_L	159_F	0.542	1.00
460_S	492_D	0.542	1.00
487_F	503_A	0.541	1.00
486_R	506_N	0.541	1.00
737_R	751_T	0.541	1.00
473_D	509_Y	0.540	1.00
385_F	388_R	0.540	1.00
610_L	625_I	0.539	1.00
93_K	103_Q	0.539	1.00
240_A	272_D	0.538	1.00
327_Q	330_W	0.538	1.00
472_Y	480_N	0.538	1.00
679_M	694_L	0.537	1.00
504_G	548_E	0.537	1.00
690_W	694_L	0.536	1.00
748_Q	789_K	0.536	1.00
151_Y	156_P	0.534	1.00
609_E	612_E	0.534	1.00
53_S	624_Q	0.533	1.00
625_I	679_M	0.531	1.00
619_V	636_L	0.531	1.00
67_L	71_N	0.530	1.00
742_P	749_N	0.529	1.00
228_F	240_A	0.528	1.00
410_I	454_Y	0.528	1.00
381_D	415_W	0.528	1.00
236_F	281_F	0.527	1.00
552_G	564_R	0.526	1.00
388_R	404_Y	0.526	1.00
667_A	701_K	0.526	1.00
240_A	278_F	0.525	1.00
399_V	404_Y	0.525	1.00
750_L	784_L	0.525	1.00
247_S	269_N	0.525	1.00
687_G	742_P	0.523	1.00
390_D	402_Q	0.523	1.00
459_I	462_R	0.522	1.00
504_G	550_A	0.522	1.00
69_R	735_D	0.522	1.00
99_A	164_G	0.521	1.00
698_E	729_D	0.521	1.00
577_S	597_G	0.520	1.00
464_V	493_I	0.520	1.00
144_L	273_T	0.520	1.00
498_T	557_I	0.520	1.00
176_A	179_S	0.518	1.00
567_Y	606_L	0.518	1.00
181_V	790_F	0.518	1.00
190_S	779_G	0.517	1.00
59_T	66_D	0.516	1.00
676_S	693_T	0.515	1.00
32_E	36_Y	0.515	1.00
474_Y	483_I	0.514	1.00
744_F	750_L	0.514	1.00
634_G	667_A	0.513	1.00
692_N	733_T	0.513	1.00
44_N	486_R	0.513	1.00
100_S	103_Q	0.513	1.00
412_S	448_I	0.512	1.00
315_N	344_D	0.512	1.00
185_Y	786_V	0.511	1.00
581_R	592_E	0.511	1.00
331_A	335_T	0.510	1.00
60_G	245_R	0.510	1.00
279_T	323_D	0.509	1.00
345_Y	375_H	0.509	1.00
70_T	693_T	0.509	1.00
694_L	762_S	0.508	1.00
175_N	230_Q	0.508	1.00
451_Y	476_N	0.508	1.00
74_V	167_I	0.508	1.00
178_D	748_Q	0.508	1.00
493_I	555_Q	0.507	1.00
163_N	510_G	0.506	1.00
162_F	508_Y	0.506	1.00
688_L	692_N	0.506	1.00
731_S	762_S	0.506	1.00
566_N	607_S	0.506	1.00
59_T	64_I	0.505	1.00
602_H	629_Y	0.505	1.00
275_L	291_T	0.505	1.00
384_T	389_L	0.504	1.00
671_N	700_R	0.504	1.00
378_Q	416_T	0.504	1.00
734_W	738_L	0.504	1.00
99_A	572_A	0.504	1.00
633_K	666_V	0.503	1.00
579_S	592_E	0.503	1.00
365_T	369_T	0.503	1.00
19_A	22_D	0.502	1.00
335_T	383_Y	0.502	1.00
181_V	184_G	0.502	1.00
610_L	679_M	0.502	1.00
191_D	248_D	0.501	1.00
575_Q	596_D	0.501	1.00
619_V	634_G	0.501	1.00
456_A	469_G	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3efmA	1	0.6924	100	0.297	Contact Map
3qlbA	1	0.757	100	0.307	Contact Map
1kmoA	1	0.7772	100	0.307	Contact Map
1xkwA	1	0.7709	100	0.308	Contact Map
2hdiA	1	0.719	100	0.312	Contact Map
2w16A	1	0.8177	100	0.313	Contact Map
4b7oA	1	0.7835	100	0.32	Contact Map
3v8xA	1	0.8367	100	0.321	Contact Map
2gufA	1	0.6886	100	0.323	Contact Map
4cu4A	1	0.7949	100	0.331	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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