YDDA - ECOLI - GREMLIN Contacts

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YDDA - Inner membrane ABC transporter ATP-binding protein YddA

UniProt:	P31826	Sequences: MITIPITLRMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILGVVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPALLGIFVLISVNKTWLIKLLTIRWREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQSLSMLITFTVILWESAGTLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRPLNVEKQRSEATFRTNLVQHNKQAELIALSNAESLQRQELSDNFHTIKENWHRLMNRQRWLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSRQAFMLVSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVADASIRTPDNKIILENLNFHVSPGKWLLLKGYSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQTPLIKTGLLKEIICKALPLPVDDKSLSEVLHQVGLGKLAARIHDHDRWGDILSSGEKQRIALARLILRRPKWIFLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLADDICDISAVL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11742
Length:	561 (515)
Sequences:	52631 (37075)
Seq/√Len:	1633.7

ECOLI - YDDA MSBA MDLB MDLA CYDD CYDC YOJI
BACSU - YHEH SUNT BMRA YFIC YGAD YKNV YWJA CYDD YHEI YKNU YFIB CYDC YVRA TAGH OPUAA
HALSA - Q9HSQ7
SULSO - Q97UJ9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
394_K	553_D	4.684	1.00
371_D	385_N	4.625	1.00
368_Q	389_H	4.549	1.00
391_S	394_K	4.450	1.00
370_A	423_D	4.244	1.00
471_G	481_D	4.169	1.00
442_G	446_E	4.127	1.00
466_H	471_G	4.011	1.00
445_K	458_D	3.994	1.00
370_A	425_S	3.533	1.00
366_A	389_H	3.455	1.00
471_G	475_A	3.396	1.00
369_V	372_A	3.275	1.00
457_D	460_S	3.176	1.00
445_K	449_C	3.127	1.00
410_L	541_V	3.013	1.00
458_D	462_S	2.978	1.00
373_S	385_N	2.948	1.00
381_I	384_E	2.890	1.00
410_L	509_F	2.789	1.00
429_D	506_K	2.719	1.00
415_H	418_P	2.709	1.00
463_E	467_Q	2.637	1.00
368_Q	425_S	2.602	1.00
448_I	465_L	2.576	1.00
390_V	396_L	2.542	1.00
366_A	391_S	2.522	1.00
462_S	471_G	2.513	1.00
504_R	536_S	2.492	1.00
452_L	460_S	2.456	1.00
445_K	461_L	2.447	1.00
170_V	174_E	2.445	1.00
431_W	505_P	2.435	1.00
61_N	309_G	2.422	1.00
375_R	381_I	2.418	1.00
388_F	555_C	2.310	1.00
462_S	466_H	2.305	1.00
21_P	350_Q	2.303	1.00
448_I	461_L	2.278	1.00
373_S	381_I	2.260	1.00
395_W	551_A	2.248	1.00
470_L	473_L	2.218	1.00
366_A	392_P	2.213	1.00
61_N	307_N	2.201	1.00
373_S	421_K	2.195	1.00
369_V	388_F	2.178	1.00
25_R	110_Y	2.163	1.00
522_A	544_Q	2.124	1.00
371_D	387_N	2.112	1.00
452_L	455_P	2.101	1.00
464_V	468_V	2.089	1.00
365_H	427_P	2.081	1.00
460_S	504_R	2.073	1.00
530_R	550_L	2.064	1.00
465_L	481_D	2.062	1.00
390_V	539_I	2.053	1.00
31_S	106_W	2.050	1.00
462_S	475_A	2.016	1.00
114_R	353_E	2.005	1.00
375_R	420_F	1.975	1.00
396_L	553_D	1.959	1.00
463_E	466_H	1.895	1.00
176_A	300_Q	1.893	1.00
72_W	76_L	1.881	1.00
226_S	263_T	1.867	1.00
449_C	461_L	1.849	1.00
449_C	458_D	1.833	1.00
523_I	527_R	1.830	1.00
445_K	481_D	1.801	1.00
396_L	555_C	1.800	1.00
467_Q	531_E	1.783	1.00
346_Y	350_Q	1.776	1.00
364_Q	427_P	1.773	1.00
76_L	80_A	1.766	1.00
517_L	525_L	1.754	1.00
469_G	524_R	1.734	1.00
465_L	474_A	1.720	1.00
367_V	539_I	1.703	1.00
448_I	502_L	1.688	1.00
383_L	386_L	1.681	1.00
27_N	32_V	1.680	1.00
221_V	343_D	1.669	1.00
397_L	551_A	1.668	1.00
456_V	502_L	1.656	1.00
143_D	344_R	1.651	1.00
472_K	475_A	1.642	1.00
249_A	252_L	1.637	1.00
409_L	557_I	1.627	1.00
398_L	409_L	1.627	1.00
395_W	540_M	1.625	1.00
366_A	427_P	1.616	1.00
394_K	552_D	1.603	1.00
460_S	463_E	1.587	1.00
173_W	180_S	1.582	1.00
459_K	462_S	1.579	1.00
117_A	353_E	1.562	1.00
465_L	471_G	1.561	1.00
398_L	555_C	1.548	1.00
542_T	547_V	1.547	1.00
57_N	313_K	1.519	1.00
229_T	263_T	1.518	1.00
391_S	553_D	1.501	1.00
73_Q	77_W	1.485	1.00
374_I	408_T	1.474	1.00
527_R	531_E	1.470	1.00
114_R	118_D	1.460	1.00
295_F	299_P	1.455	1.00
460_S	502_L	1.452	1.00
414_S	432_Y	1.443	1.00
412_T	424_I	1.441	1.00
449_C	456_V	1.438	1.00
458_D	461_L	1.433	1.00
233_N	260_N	1.433	1.00
473_L	491_E	1.431	1.00
363_C	427_P	1.420	1.00
21_P	346_Y	1.418	1.00
299_P	303_S	1.414	1.00
53_N	317_A	1.404	1.00
365_H	392_P	1.400	1.00
531_E	534_P	1.395	1.00
41_M	88_I	1.386	1.00
374_I	412_T	1.383	1.00
374_I	417_W	1.380	1.00
372_A	419_W	1.377	1.00
369_V	413_L	1.376	1.00
253_Q	450_K	1.364	1.00
431_W	500_L	1.353	1.00
397_L	548_W	1.350	1.00
401_Y	558_S	1.347	1.00
444_L	495_I	1.347	1.00
173_W	177_G	1.341	1.00
222_E	267_N	1.316	1.00
215_R	218_P	1.314	1.00
452_L	456_V	1.307	1.00
114_R	349_H	1.302	1.00
370_A	387_N	1.299	1.00
459_K	463_E	1.294	1.00
469_G	521_E	1.289	1.00
207_L	211_K	1.286	1.00
468_V	498_A	1.276	1.00
226_S	267_N	1.273	1.00
396_L	539_I	1.268	1.00
402_S	521_E	1.268	1.00
465_L	470_L	1.267	1.00
373_S	384_E	1.264	1.00
470_L	474_A	1.262	1.00
475_A	480_H	1.252	1.00
226_S	229_T	1.250	1.00
467_Q	501_I	1.249	1.00
413_L	539_I	1.238	1.00
366_A	428_A	1.237	1.00
172_L	314_S	1.234	1.00
462_S	465_L	1.234	1.00
476_R	491_E	1.232	1.00
457_D	502_L	1.228	1.00
493_Q	515_S	1.224	1.00
50_V	167_T	1.224	1.00
533_L	538_V	1.223	1.00
392_P	506_K	1.219	1.00
386_L	409_L	1.212	1.00
371_D	421_K	1.196	1.00
179_L	314_S	1.193	1.00
69_D	73_Q	1.186	1.00
464_V	501_I	1.185	1.00
251_S	255_Q	1.182	1.00
255_Q	259_D	1.180	1.00
473_L	477_I	1.180	1.00
245_A	250_E	1.179	1.00
262_H	266_E	1.178	1.00
390_V	537_G	1.177	1.00
388_F	409_L	1.175	1.00
300_Q	305_Q	1.175	1.00
237_H	253_Q	1.173	1.00
109_D	113_N	1.173	1.00
307_N	310_G	1.168	1.00
487_L	495_I	1.166	1.00
240_Q	438_L	1.164	1.00
57_N	61_N	1.161	1.00
364_Q	392_P	1.157	1.00
44_G	88_I	1.157	1.00
462_S	481_D	1.154	1.00
124_T	417_W	1.134	1.00
369_V	424_I	1.132	1.00
381_I	420_F	1.131	1.00
98_L	102_R	1.130	1.00
500_L	508_I	1.117	1.00
395_W	538_V	1.110	1.00
177_G	181_F	1.108	1.00
257_L	261_F	1.106	1.00
114_R	117_A	1.106	1.00
132_N	135_N	1.103	1.00
542_T	548_W	1.101	1.00
135_N	228_A	1.101	1.00
178_T	305_Q	1.094	1.00
55_W	74_L	1.086	1.00
111_Y	348_F	1.086	1.00
131_K	135_N	1.086	1.00
433_V	500_L	1.084	1.00
297_L	311_L	1.080	1.00
467_Q	532_K	1.078	1.00
113_N	117_A	1.072	1.00
253_Q	256_E	1.072	1.00
296_L	300_Q	1.071	1.00
469_G	528_L	1.068	1.00
54_D	58_D	1.067	1.00
458_D	481_D	1.066	1.00
36_I	40_A	1.065	1.00
402_S	494_R	1.064	1.00
512_E	543_H	1.060	1.00
124_T	411_K	1.058	1.00
367_V	413_L	1.057	1.00
412_T	419_W	1.055	1.00
369_V	409_L	1.054	1.00
229_T	260_N	1.052	1.00
146_L	341_V	1.052	1.00
367_V	426_S	1.051	1.00
259_D	263_T	1.049	1.00
399_K	556_D	1.046	1.00
472_K	476_R	1.046	1.00
342_I	346_Y	1.046	1.00
219_L	270_R	1.045	1.00
456_V	460_S	1.043	1.00
24_L	27_N	1.042	1.00
372_A	412_T	1.040	1.00
270_R	273_N	1.039	1.00
464_V	502_L	1.038	1.00
376_T	382_I	1.038	1.00
506_K	536_S	1.035	1.00
41_M	91_N	1.034	1.00
508_I	536_S	1.034	1.00
166_I	170_V	1.033	1.00
540_M	551_A	1.032	1.00
244_I	253_Q	1.030	1.00
265_K	269_H	1.029	1.00
32_V	36_I	1.027	1.00
201_I	289_L	1.025	1.00
34_L	98_L	1.022	1.00
437_P	496_A	1.022	1.00
446_E	449_C	1.022	1.00
397_L	542_T	1.017	1.00
407_T	411_K	1.006	1.00
489_S	494_R	1.005	1.00
469_G	531_E	1.001	1.00
80_A	84_I	0.999	1.00
368_Q	387_N	0.996	1.00
368_Q	428_A	0.995	1.00
301_F	306_I	0.994	1.00
38_I	96_I	0.992	1.00
469_G	527_R	0.990	1.00
57_N	310_G	0.989	1.00
256_E	260_N	0.988	1.00
110_Y	114_R	0.987	1.00
143_D	341_V	0.984	1.00
544_Q	547_V	0.983	1.00
249_A	253_Q	0.982	1.00
211_K	215_R	0.981	1.00
106_W	110_Y	0.981	1.00
33_L	37_I	0.981	1.00
119_K	354_Q	0.980	1.00
445_K	462_S	0.977	1.00
222_E	226_S	0.977	1.00
215_R	274_R	0.976	1.00
233_N	256_E	0.976	1.00
181_F	200_L	0.974	1.00
41_M	95_L	0.973	1.00
463_E	504_R	0.968	1.00
28_N	106_W	0.966	1.00
28_N	32_V	0.966	1.00
375_R	382_I	0.965	1.00
524_R	527_R	0.963	1.00
362_N	427_P	0.960	1.00
497_L	510_L	0.960	1.00
258_S	262_H	0.959	1.00
385_N	421_K	0.955	1.00
397_L	554_I	0.954	1.00
426_S	507_W	0.953	1.00
381_I	421_K	0.953	1.00
464_V	498_A	0.949	1.00
221_V	225_R	0.948	1.00
252_L	256_E	0.947	1.00
466_H	475_A	0.941	1.00
461_L	502_L	0.937	1.00
448_I	495_I	0.937	1.00
419_W	424_I	0.930	1.00
105_E	109_D	0.929	1.00
73_Q	76_L	0.929	1.00
377_P	380_K	0.928	1.00
139_R	347_E	0.923	1.00
58_D	62_A	0.923	1.00
375_R	379_N	0.922	1.00
520_Q	524_R	0.921	1.00
219_L	267_N	0.920	1.00
262_H	265_K	0.917	1.00
298_L	302_I	0.916	1.00
395_W	530_R	0.916	1.00
263_T	267_N	0.915	1.00
122_Y	131_K	0.913	1.00
242_E	411_K	0.912	1.00
222_E	270_R	0.908	1.00
208_F	281_W	0.906	1.00
175_S	310_G	0.906	1.00
339_A	343_D	0.905	1.00
392_P	427_P	0.905	1.00
111_Y	140_I	0.904	1.00
360_P	363_C	0.903	1.00
395_W	533_L	0.903	1.00
433_V	497_L	0.902	1.00
31_S	102_R	0.899	1.00
514_T	525_L	0.897	1.00
355_R	418_P	0.897	1.00
439_I	495_I	0.896	1.00
200_L	203_I	0.889	1.00
404_A	557_I	0.889	1.00
414_S	430_S	0.887	1.00
414_S	509_F	0.886	1.00
440_K	447_I	0.885	1.00
419_W	423_D	0.883	1.00
470_L	495_I	0.883	1.00
470_L	476_R	0.880	1.00
25_R	28_N	0.878	1.00
467_Q	471_G	0.876	1.00
169_T	180_S	0.874	1.00
373_S	420_F	0.874	1.00
121_Y	354_Q	0.874	1.00
439_I	492_K	0.873	1.00
508_I	533_L	0.868	1.00
111_Y	345_L	0.865	1.00
505_P	536_S	0.862	1.00
300_Q	303_S	0.862	1.00
114_R	352_T	0.857	1.00
526_L	542_T	0.855	1.00
48_I	84_I	0.855	1.00
172_L	180_S	0.855	1.00
197_T	296_L	0.854	1.00
223_K	268_W	0.852	1.00
176_A	180_S	0.852	1.00
218_P	222_E	0.847	1.00
255_Q	258_S	0.847	1.00
206_T	210_H	0.847	1.00
254_R	258_S	0.846	1.00
252_L	255_Q	0.846	1.00
21_P	24_L	0.845	1.00
48_I	88_I	0.843	1.00
443_L	446_E	0.842	1.00
215_R	219_L	0.841	1.00
251_S	254_R	0.839	1.00
449_C	455_P	0.837	1.00
38_I	99_L	0.835	1.00
375_R	378_D	0.835	1.00
171_I	175_S	0.833	1.00
243_L	247_S	0.831	1.00
28_N	31_S	0.831	1.00
367_V	507_W	0.830	1.00
118_D	351_L	0.828	1.00
370_A	389_H	0.828	1.00
526_L	547_V	0.827	1.00
256_E	259_D	0.826	1.00
210_H	214_K	0.826	1.00
468_V	494_R	0.825	1.00
477_I	487_L	0.824	1.00
42_I	160_Q	0.821	1.00
449_C	452_L	0.821	1.00
87_L	91_N	0.821	1.00
135_N	139_R	0.820	1.00
365_H	537_G	0.819	1.00
489_S	516_H	0.817	1.00
178_T	181_F	0.817	1.00
522_A	526_L	0.816	1.00
174_E	177_G	0.814	1.00
545_P	556_D	0.814	1.00
136_P	348_F	0.813	1.00
301_F	311_L	0.813	1.00
74_L	77_W	0.807	1.00
267_N	270_R	0.807	1.00
260_N	263_T	0.804	1.00
44_G	84_I	0.803	1.00
48_I	81_L	0.801	1.00
58_D	61_N	0.798	1.00
40_A	44_G	0.797	1.00
70_K	73_Q	0.796	1.00
508_I	538_V	0.796	1.00
514_T	522_A	0.795	1.00
240_Q	243_L	0.795	1.00
55_W	81_L	0.793	1.00
345_L	349_H	0.791	1.00
58_D	74_L	0.791	1.00
47_K	51_W	0.791	1.00
402_S	512_E	0.790	1.00
425_S	428_A	0.789	1.00
226_S	260_N	0.785	1.00
178_T	300_Q	0.784	1.00
119_K	355_R	0.783	1.00
61_N	64_S	0.782	1.00
399_K	545_P	0.782	1.00
263_T	266_E	0.782	1.00
284_I	288_S	0.780	1.00
121_Y	130_H	0.780	1.00
150_K	338_L	0.778	1.00
67_E	70_K	0.778	1.00
444_L	474_A	0.777	1.00
75_V	79_P	0.777	1.00
309_G	313_K	0.777	1.00
473_L	476_R	0.776	1.00
269_H	273_N	0.774	1.00
436_T	492_K	0.774	1.00
393_G	537_G	0.772	1.00
230_F	264_I	0.769	1.00
34_L	95_L	0.769	1.00
46_V	163_S	0.768	1.00
241_A	245_A	0.768	1.00
493_Q	516_H	0.768	1.00
362_N	506_K	0.767	1.00
90_V	94_W	0.767	1.00
76_L	79_P	0.766	1.00
62_A	70_K	0.762	1.00
171_I	174_E	0.761	1.00
60_F	312_M	0.760	1.00
161_S	327_W	0.760	1.00
54_D	171_I	0.759	1.00
34_L	102_R	0.758	1.00
63_L	66_K	0.758	1.00
222_E	225_R	0.757	1.00
214_K	218_P	0.753	1.00
430_S	507_W	0.753	1.00
146_L	337_E	0.748	1.00
55_W	77_W	0.748	1.00
266_E	270_R	0.743	1.00
139_R	143_D	0.741	1.00
115_W	123_F	0.741	1.00
118_D	353_E	0.739	1.00
77_W	80_A	0.739	1.00
84_I	88_I	0.738	1.00
37_I	95_L	0.737	1.00
54_D	57_N	0.737	1.00
494_R	521_E	0.736	1.00
469_G	472_K	0.736	1.00
62_A	65_Q	0.735	1.00
113_N	254_R	0.735	1.00
168_F	320_L	0.734	1.00
525_L	528_L	0.733	1.00
176_A	306_I	0.732	1.00
460_S	464_V	0.732	1.00
376_T	408_T	0.731	1.00
352_T	356_P	0.731	1.00
467_Q	528_L	0.730	1.00
23_W	26_K	0.728	1.00
452_L	503_R	0.728	1.00
411_K	417_W	0.727	1.00
383_L	557_I	0.727	1.00
110_Y	113_N	0.727	1.00
364_Q	537_G	0.726	1.00
458_D	465_L	0.724	1.00
167_T	170_V	0.720	1.00
369_V	386_L	0.720	1.00
393_G	535_T	0.718	1.00
170_V	173_W	0.717	1.00
180_S	314_S	0.715	1.00
548_W	551_A	0.715	1.00
355_R	415_H	0.714	1.00
475_A	481_D	0.714	1.00
343_D	347_E	0.714	1.00
461_L	481_D	0.712	1.00
168_F	321_V	0.712	1.00
83_G	87_L	0.710	1.00
297_L	301_F	0.709	1.00
175_S	313_K	0.708	1.00
452_L	504_R	0.706	1.00
300_Q	304_G	0.706	1.00
162_L	166_I	0.706	1.00
120_N	124_T	0.705	1.00
111_Y	349_H	0.704	1.00
390_V	394_K	0.703	1.00
143_D	224_Q	0.703	1.00
31_S	34_L	0.702	1.00
104_R	148_I	0.701	1.00
176_A	179_L	0.698	1.00
104_R	108_T	0.697	1.00
441_T	486_I	0.696	1.00
138_Q	231_R	0.696	1.00
110_Y	349_H	0.696	1.00
410_L	539_I	0.696	1.00
207_L	210_H	0.695	1.00
462_S	474_A	0.694	1.00
150_K	335_L	0.693	1.00
358_N	361_K	0.693	1.00
132_N	232_T	0.684	1.00
374_I	382_I	0.684	1.00
70_K	74_L	0.682	1.00
509_F	539_I	0.681	1.00
224_Q	227_E	0.681	1.00
384_E	559_A	0.680	1.00
338_L	341_V	0.680	1.00
517_L	521_E	0.680	1.00
436_T	483_W	0.680	1.00
283_N	326_S	0.678	1.00
177_G	180_S	0.677	1.00
33_L	36_I	0.677	1.00
147_L	342_I	0.677	1.00
51_W	81_L	0.676	1.00
395_W	550_L	0.675	1.00
111_Y	144_I	0.675	1.00
497_L	501_I	0.674	1.00
398_L	539_I	0.674	1.00
158_F	162_L	0.674	1.00
465_L	498_A	0.674	1.00
54_D	175_S	0.673	1.00
107_L	144_I	0.672	1.00
412_T	417_W	0.672	1.00
522_A	547_V	0.671	1.00
36_I	39_L	0.670	1.00
102_R	105_E	0.670	1.00
474_A	481_D	0.669	1.00
61_N	65_Q	0.667	1.00
522_A	546_G	0.666	1.00
427_P	506_K	0.664	1.00
468_V	497_L	0.664	1.00
228_A	344_R	0.663	1.00
518_E	521_E	0.663	1.00
288_S	292_L	0.660	1.00
114_R	351_L	0.658	1.00
22_F	25_R	0.656	1.00
468_V	501_I	0.655	1.00
494_R	517_L	0.654	1.00
50_V	53_N	0.654	1.00
105_E	261_F	0.654	1.00
488_S	491_E	0.653	1.00
390_V	395_W	0.651	1.00
469_G	525_L	0.651	1.00
296_L	299_P	0.651	1.00
135_N	344_R	0.650	1.00
365_H	506_K	0.650	1.00
219_L	222_E	0.649	1.00
449_C	465_L	0.648	1.00
270_R	274_R	0.648	1.00
173_W	199_V	0.648	1.00
142_E	145_L	0.647	1.00
519_E	522_A	0.647	1.00
463_E	532_K	0.647	1.00
372_A	422_G	0.646	1.00
168_F	317_A	0.645	1.00
391_S	396_L	0.645	1.00
435_Q	489_S	0.643	1.00
224_Q	340_A	0.643	1.00
72_W	75_V	0.643	1.00
526_L	540_M	0.640	1.00
23_W	27_N	0.640	1.00
272_M	276_R	0.640	1.00
461_L	464_V	0.640	1.00
208_F	285_Y	0.638	1.00
363_C	429_D	0.637	1.00
323_N	327_W	0.636	1.00
466_H	472_K	0.636	1.00
452_L	457_D	0.635	1.00
375_R	421_K	0.635	1.00
372_A	387_N	0.635	1.00
69_D	72_W	0.634	1.00
306_I	310_G	0.634	1.00
298_L	301_F	0.634	1.00
497_L	525_L	0.633	1.00
179_L	300_Q	0.633	1.00
107_L	147_L	0.633	1.00
386_L	555_C	0.633	1.00
220_N	271_L	0.632	1.00
45_V	89_S	0.632	1.00
31_S	103_W	0.631	1.00
528_L	531_E	0.630	1.00
507_W	537_G	0.629	1.00
97_K	153_S	0.628	1.00
526_L	550_L	0.625	1.00
138_Q	228_A	0.623	1.00
199_V	203_I	0.622	1.00
372_A	424_I	0.621	1.00
410_L	432_Y	0.620	1.00
381_I	385_N	0.618	1.00
465_L	468_V	0.616	1.00
266_E	269_H	0.616	1.00
471_G	474_A	0.616	1.00
138_Q	227_E	0.615	1.00
147_L	345_L	0.615	1.00
545_P	550_L	0.615	1.00
212_V	278_L	0.615	1.00
375_R	380_K	0.614	1.00
501_I	532_K	0.614	1.00
42_I	92_K	0.613	1.00
431_W	503_R	0.611	1.00
433_V	510_L	0.607	1.00
149_S	153_S	0.607	1.00
88_I	91_N	0.604	1.00
122_Y	136_P	0.604	1.00
222_E	263_T	0.603	1.00
399_K	548_W	0.602	1.00
79_P	83_G	0.601	1.00
444_L	470_L	0.601	1.00
358_N	362_N	0.600	1.00
219_L	271_L	0.600	1.00
100_T	152_L	0.599	1.00
178_T	296_L	0.599	1.00
54_D	313_K	0.598	1.00
527_R	530_R	0.598	1.00
452_L	502_L	0.598	1.00
391_S	537_G	0.597	1.00
363_C	392_P	0.597	1.00
225_R	229_T	0.595	1.00
44_G	48_I	0.595	1.00
243_L	246_L	0.595	1.00
527_R	550_L	0.595	1.00
378_D	420_F	0.594	1.00
157_G	327_W	0.594	1.00
449_C	502_L	0.592	1.00
292_L	296_L	0.588	1.00
402_S	517_L	0.587	1.00
382_I	386_L	0.587	1.00
203_I	207_L	0.587	1.00
395_W	535_T	0.586	1.00
91_N	95_L	0.586	1.00
149_S	334_E	0.586	1.00
165_L	169_T	0.585	1.00
472_K	491_E	0.584	1.00
368_Q	423_D	0.584	1.00
57_N	309_G	0.584	1.00
545_P	548_W	0.583	1.00
434_S	437_P	0.583	1.00
390_V	555_C	0.582	1.00
461_L	465_L	0.580	1.00
411_K	432_Y	0.579	1.00
533_L	536_S	0.579	1.00
521_E	525_L	0.578	1.00
507_W	539_I	0.578	1.00
363_C	426_S	0.577	1.00
160_Q	164_M	0.577	1.00
119_K	122_Y	0.577	1.00
169_T	173_W	0.576	1.00
341_V	344_R	0.575	1.00
306_I	311_L	0.575	1.00
226_S	264_I	0.573	1.00
144_I	345_L	0.573	1.00
373_S	383_L	0.572	1.00
402_S	542_T	0.572	1.00
94_W	98_L	0.572	1.00
287_R	291_V	0.572	1.00
112_L	116_F	0.572	1.00
302_I	305_Q	0.571	1.00
490_G	518_E	0.569	1.00
384_E	387_N	0.568	1.00
297_L	300_Q	0.568	1.00
101_I	104_R	0.568	1.00
408_T	417_W	0.565	1.00
448_I	451_A	0.564	1.00
121_Y	377_P	0.564	1.00
244_I	250_E	0.564	1.00
120_N	416_C	0.563	1.00
55_W	78_F	0.563	1.00
447_I	495_I	0.563	1.00
540_M	548_W	0.562	1.00
204_G	207_L	0.560	1.00
133_T	137_D	0.560	1.00
21_P	25_R	0.559	1.00
227_E	231_R	0.559	1.00
134_D	232_T	0.558	1.00
138_Q	142_E	0.557	1.00
34_L	99_L	0.557	1.00
398_L	541_V	0.557	1.00
161_S	165_L	0.557	1.00
97_K	101_I	0.555	1.00
519_E	546_G	0.555	1.00
433_V	513_T	0.555	1.00
459_K	466_H	0.555	1.00
198_V	318_F	0.554	1.00
528_L	532_K	0.554	1.00
299_P	302_I	0.552	1.00
228_A	340_A	0.550	1.00
223_K	271_L	0.548	1.00
140_I	144_I	0.548	1.00
77_W	81_L	0.547	1.00
510_L	513_T	0.547	1.00
211_K	214_K	0.547	1.00
233_N	237_H	0.547	1.00
369_V	412_T	0.546	1.00
123_F	131_K	0.546	1.00
494_R	516_H	0.546	1.00
456_V	461_L	0.544	1.00
514_T	517_L	0.544	1.00
174_E	178_T	0.542	1.00
378_D	381_I	0.542	1.00
407_T	410_L	0.542	1.00
468_V	528_L	0.540	1.00
389_H	392_P	0.540	1.00
532_K	535_T	0.539	1.00
45_V	88_I	0.538	1.00
156_F	159_I	0.537	1.00
363_C	366_A	0.537	1.00
542_T	550_L	0.536	1.00
398_L	557_I	0.535	1.00
513_T	540_M	0.534	1.00
276_R	280_Y	0.534	1.00
545_P	554_I	0.534	1.00
171_I	317_A	0.533	1.00
542_T	546_G	0.533	1.00
71_L	75_V	0.533	1.00
142_E	224_Q	0.533	1.00
240_Q	440_K	0.532	1.00
445_K	502_L	0.532	1.00
229_T	232_T	0.531	1.00
86_V	90_V	0.530	1.00
501_I	528_L	0.530	1.00
145_L	148_I	0.530	1.00
204_G	208_F	0.530	1.00
367_V	390_V	0.529	1.00
547_V	551_A	0.529	1.00
116_F	119_K	0.528	1.00
230_F	234_L	0.528	1.00
235_V	239_K	0.527	1.00
139_R	344_R	0.527	1.00
521_E	524_R	0.527	1.00
25_R	107_L	0.526	1.00
115_W	136_P	0.526	1.00
219_L	274_R	0.525	1.00
532_K	536_S	0.525	1.00
539_I	555_C	0.525	1.00
167_T	317_A	0.525	1.00
130_H	377_P	0.524	1.00
513_T	542_T	0.524	1.00
386_L	557_I	0.524	1.00
444_L	477_I	0.523	1.00
233_N	253_Q	0.523	1.00
21_P	27_N	0.523	1.00
59_F	74_L	0.522	1.00
490_G	494_R	0.522	1.00
38_I	95_L	0.522	1.00
373_S	387_N	0.521	1.00
259_D	262_H	0.521	1.00
52_L	56_N	0.520	1.00
49_Q	85_F	0.520	1.00
34_L	38_I	0.520	1.00
410_L	414_S	0.520	1.00
39_L	42_I	0.519	1.00
22_F	26_K	0.519	1.00
465_L	475_A	0.519	1.00
408_T	412_T	0.518	1.00
55_W	58_D	0.518	1.00
176_A	181_F	0.517	1.00
351_L	354_Q	0.517	1.00
451_A	456_V	0.517	1.00
101_I	105_E	0.516	1.00
46_V	50_V	0.516	1.00
45_V	49_Q	0.515	1.00
264_I	268_W	0.515	1.00
362_N	365_H	0.513	1.00
104_R	144_I	0.513	1.00
365_H	507_W	0.513	1.00
130_H	351_L	0.513	1.00
131_K	136_P	0.513	1.00
291_V	295_F	0.513	1.00
352_T	355_R	0.512	1.00
161_S	328_F	0.511	1.00
266_E	273_N	0.510	1.00
493_Q	514_T	0.507	1.00
547_V	550_L	0.506	1.00
118_D	348_F	0.505	1.00
124_T	242_E	0.505	1.00
468_V	473_L	0.505	1.00
206_T	209_T	0.505	1.00
161_S	164_M	0.504	1.00
484_G	492_K	0.504	1.00
540_M	550_L	0.504	1.00
118_D	122_Y	0.503	1.00
203_I	206_T	0.503	1.00
400_G	406_K	0.502	1.00
93_T	97_K	0.502	1.00
42_I	46_V	0.502	1.00
474_A	478_H	0.501	1.00
115_W	348_F	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.943	100	0.144	Contact Map
4a82A	2	0.9287	100	0.175	Contact Map
4q4hB	1	0.9465	100	0.198	Contact Map
3b60A	2	0.934	100	0.208	Contact Map
3b5xA	2	0.934	100	0.209	Contact Map
4q9hA	1	0.9376	100	0.216	Contact Map
3zdqA	2	0.9358	100	0.221	Contact Map
4q4hA	1	0.9323	100	0.223	Contact Map
4mrsA	2	0.9501	100	0.229	Contact Map
3wmgA	1	0.934	100	0.233	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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