NNR - ECOLI - GREMLIN Contacts

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NNR - Bifunctional NAD(P)H-hydrate repair enzyme Nnr

UniProt:	P31806	Sequences: MTDHTMKKNPVSIPHTVWYADDIRRGEREAADVLGLTLYELMLRAGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLAKAVGIEVTLLAQESDKPLPEEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLRQAPRESISQLIDHANSHPAPIVAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLGLDSWLAGQETKIQRFSAEQLSHWLKPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEAALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMDSLTESLEWADVVVIGPGLGQQEWGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIESDRLHCAKRLVQRYGGVAVLKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGALLGQKLSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQRIVNPEVTDKNHDESSNSAP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11758
Length:	515 (480)
Sequences:	3495 (2775)
Seq/√Len:	126.7

ECOLI - NNR
HALSA - Q9HQ90
SULSO - Q97WG6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
76_G	136_A	5.017	1.00
410_V	466_C	4.584	1.00
325_V	445_S	4.449	1.00
325_V	449_G	3.979	1.00
46_G	78_V	3.744	1.00
146_P	154_I	3.148	1.00
448_I	465_G	3.124	1.00
257_L	449_G	3.022	1.00
49_A	167_V	3.022	1.00
393_D	396_H	2.851	1.00
43_L	81_R	2.851	1.00
112_W	117_G	2.818	1.00
261_G	270_I	2.797	1.00
432_N	474_D	2.740	1.00
28_R	32_D	2.720	1.00
66_L	157_A	2.704	1.00
430_A	470_G	2.606	1.00
144_Q	147_R	2.554	1.00
331_G	355_D	2.516	1.00
352_W	356_A	2.489	1.00
256_R	286_R	2.468	1.00
209_T	212_L	2.458	1.00
56_A	211_Q	2.391	1.00
280_A	447_I	2.324	1.00
20_A	176_E	2.320	1.00
79_V	167_V	2.317	1.00
38_L	104_E	2.313	1.00
358_N	381_R	2.290	1.00
53_C	165_V	2.262	1.00
398_A	417_V	2.246	1.00
155_D	183_A	2.234	1.00
49_A	79_V	2.182	1.00
48_A	215_D	2.169	1.00
77_Y	94_A	2.151	1.00
280_A	450_A	2.147	1.00
440_M	490_L	2.126	1.00
50_F	79_V	2.107	1.00
200_L	209_T	2.088	1.00
157_A	164_I	2.074	1.00
64_L	130_V	2.074	1.00
164_I	185_I	2.065	1.00
62_H	131_D	2.053	1.00
189_H	213_H	2.022	1.00
371_V	448_I	2.018	1.00
426_G	463_C	1.986	1.00
435_M	440_M	1.966	1.00
157_A	185_I	1.958	1.00
366_K	370_R	1.945	1.00
332_Q	358_N	1.937	1.00
457_S	460_D	1.899	1.00
284_L	438_G	1.884	1.00
95_Q	137_L	1.874	1.00
371_V	452_L	1.862	1.00
54_R	86_V	1.859	1.00
174_L	181_P	1.853	1.00
137_L	154_I	1.852	1.00
53_C	132_L	1.823	1.00
52_V	213_H	1.822	1.00
257_L	282_A	1.798	1.00
400_R	404_R	1.797	1.00
190_T	210_G	1.793	1.00
53_C	134_V	1.786	1.00
148_E	152_Q	1.780	1.00
274_G	304_L	1.765	1.00
475_V	497_I	1.765	1.00
67_C	76_G	1.759	1.00
272_M	488_T	1.753	1.00
401_L	409_A	1.736	1.00
65_V	80_A	1.728	1.00
136_A	167_V	1.723	1.00
379_A	383_L	1.721	1.00
163_P	188_D	1.718	1.00
52_V	189_H	1.714	1.00
379_A	401_L	1.704	1.00
428_I	470_G	1.678	1.00
63_W	88_I	1.676	1.00
42_M	74_G	1.671	1.00
138_L	144_Q	1.636	1.00
56_A	189_H	1.634	1.00
386_S	389_E	1.627	1.00
80_A	92_L	1.623	1.00
154_I	158_N	1.616	1.00
165_V	189_H	1.612	1.00
191_I	215_D	1.605	1.00
459_Y	463_C	1.602	1.00
138_L	142_L	1.602	1.00
410_V	448_I	1.600	1.00
282_A	285_V	1.597	1.00
276_A	491_F	1.594	1.00
196_L	214_F	1.586	1.00
106_A	110_E	1.570	1.00
279_R	489_D	1.570	1.00
19_Y	22_D	1.561	1.00
249_S	254_H	1.556	1.00
52_V	191_I	1.547	1.00
447_I	465_G	1.546	1.00
21_D	25_R	1.544	1.00
435_M	473_A	1.541	1.00
31_A	38_L	1.508	1.00
408_V	462_A	1.507	1.00
279_R	486_L	1.503	1.00
326_I	352_W	1.503	1.00
173_L	184_V	1.500	1.00
25_R	28_R	1.496	1.00
445_S	449_G	1.494	1.00
301_R	304_L	1.489	1.00
196_L	201_L	1.475	1.00
398_A	419_A	1.471	1.00
380_A	390_I	1.460	1.00
196_L	212_L	1.454	1.00
184_V	208_V	1.441	1.00
243_K	456_L	1.441	1.00
178_G	199_G	1.430	1.00
437_S	487_A	1.425	1.00
53_C	79_V	1.424	1.00
447_I	494_L	1.420	1.00
65_V	76_G	1.416	1.00
479_R	493_T	1.409	1.00
257_L	277_A	1.400	1.00
20_A	175_A	1.400	1.00
180_T	208_V	1.389	1.00
261_G	328_P	1.387	1.00
148_E	151_S	1.385	1.00
151_S	155_D	1.383	1.00
39_Y	107_L	1.371	1.00
401_L	405_Y	1.368	1.00
372_I	409_A	1.367	1.00
272_M	443_V	1.364	1.00
486_L	489_D	1.356	1.00
138_L	171_S	1.354	1.00
47_E	51_Q	1.349	1.00
109_R	113_L	1.343	1.00
475_V	493_T	1.342	1.00
351_L	445_S	1.342	1.00
476_L	493_T	1.341	1.00
245_R	254_H	1.340	1.00
455_K	461_A	1.332	1.00
351_L	452_L	1.326	1.00
379_A	411_L	1.322	1.00
303_E	488_T	1.316	1.00
199_G	205_A	1.315	1.00
323_V	449_G	1.314	1.00
328_P	445_S	1.305	1.00
18_W	195_A	1.302	1.00
62_H	89_E	1.294	1.00
434_G	485_M	1.290	1.00
366_K	369_N	1.289	1.00
400_R	403_Q	1.287	1.00
275_E	492_S	1.287	1.00
47_E	82_L	1.280	1.00
194_I	219_L	1.280	1.00
259_I	270_I	1.272	1.00
274_G	287_V	1.271	1.00
49_A	193_F	1.268	1.00
154_I	171_S	1.265	1.00
151_S	183_A	1.264	1.00
340_L	359_L	1.261	1.00
18_W	23_I	1.258	1.00
138_L	147_R	1.255	1.00
257_L	323_V	1.247	1.00
383_L	401_L	1.246	1.00
84_K	117_G	1.245	1.00
69_H	144_Q	1.241	1.00
91_T	120_H	1.239	1.00
371_V	462_A	1.233	1.00
395_L	425_L	1.232	1.00
62_H	91_T	1.231	1.00
174_L	177_T	1.227	0.99
333_Q	336_G	1.225	0.99
426_G	459_Y	1.222	0.99
25_R	29_E	1.219	0.99
452_L	458_P	1.217	0.99
232_R	429_D	1.215	0.99
103_E	106_A	1.207	0.99
277_A	285_V	1.203	0.99
473_A	476_L	1.203	0.99
417_V	425_L	1.202	0.99
180_T	184_V	1.200	0.99
64_L	93_L	1.193	0.99
78_V	81_R	1.192	0.99
351_L	465_G	1.182	0.99
234_S	237_Q	1.182	0.99
443_V	491_F	1.180	0.99
476_L	489_D	1.180	0.99
194_I	216_S	1.180	0.99
259_I	273_T	1.176	0.99
326_I	343_V	1.167	0.99
396_H	400_R	1.166	0.99
65_V	79_V	1.165	0.99
376_P	394_R	1.163	0.99
267_A	298_L	1.161	0.99
286_R	305_M	1.158	0.99
69_H	96_E	1.151	0.99
205_A	209_T	1.146	0.99
278_L	486_L	1.141	0.99
399_K	425_L	1.140	0.99
275_E	301_R	1.139	0.99
266_T	305_M	1.134	0.99
401_L	407_G	1.133	0.99
471_A	474_D	1.133	0.99
50_F	86_V	1.119	0.99
65_V	136_A	1.116	0.99
145_A	181_P	1.115	0.99
79_V	134_V	1.112	0.99
149_S	152_Q	1.112	0.99
372_I	407_G	1.112	0.99
142_L	181_P	1.105	0.99
84_K	112_W	1.092	0.99
133_I	157_A	1.090	0.99
77_Y	112_W	1.089	0.99
257_L	453_G	1.080	0.99
270_I	287_V	1.076	0.99
92_L	112_W	1.074	0.99
434_G	474_D	1.073	0.99
467_V	471_A	1.073	0.99
332_Q	359_L	1.071	0.99
138_L	150_I	1.070	0.99
379_A	397_C	1.068	0.99
332_Q	362_I	1.064	0.99
40_E	44_R	1.062	0.99
408_V	421_H	1.057	0.98
252_G	376_P	1.055	0.98
287_V	297_L	1.054	0.98
173_L	208_V	1.050	0.98
39_Y	108_A	1.042	0.98
52_V	55_S	1.039	0.98
398_A	402_V	1.037	0.98
258_V	288_L	1.035	0.98
206_R	415_G	1.034	0.98
437_S	440_M	1.032	0.98
97_S	100_P	1.031	0.98
289_T	297_L	1.031	0.98
201_L	212_L	1.024	0.98
49_A	191_I	1.022	0.98
67_C	136_A	1.020	0.98
80_A	90_V	1.018	0.98
428_I	466_C	1.014	0.98
18_W	26_G	1.014	0.98
91_T	130_V	1.009	0.98
200_L	212_L	1.007	0.98
17_V	201_L	1.006	0.98
54_R	88_I	1.005	0.98
95_Q	153_L	1.005	0.98
376_P	391_E	1.004	0.98
60_A	131_D	1.004	0.98
473_A	477_A	1.000	0.98
402_V	419_A	0.999	0.98
192_T	200_L	0.995	0.98
462_A	465_G	0.994	0.98
332_Q	381_R	0.989	0.98
201_L	232_R	0.986	0.98
127_P	130_V	0.985	0.98
467_V	470_G	0.985	0.98
94_A	109_R	0.981	0.98
332_Q	355_D	0.981	0.98
479_R	496_R	0.979	0.97
258_V	321_A	0.979	0.97
419_A	422_P	0.977	0.97
420_A	459_Y	0.972	0.97
256_R	284_L	0.971	0.97
289_T	293_N	0.971	0.97
37_T	40_E	0.969	0.97
326_I	340_L	0.968	0.97
271_R	300_A	0.965	0.97
257_L	325_V	0.965	0.97
258_V	324_V	0.964	0.97
294_I	298_L	0.963	0.97
245_R	434_G	0.962	0.97
23_I	195_A	0.959	0.97
367_R	370_R	0.957	0.97
67_C	77_Y	0.956	0.97
358_N	361_A	0.956	0.97
438_G	487_A	0.955	0.97
174_L	179_A	0.955	0.97
52_V	56_A	0.946	0.97
69_H	100_P	0.934	0.97
57_Y	165_V	0.932	0.97
424_A	459_Y	0.929	0.97
385_C	389_E	0.928	0.97
402_V	421_H	0.928	0.97
50_F	83_A	0.925	0.96
416_T	466_C	0.924	0.96
186_N	207_D	0.924	0.96
408_V	420_A	0.922	0.96
108_A	111_A	0.921	0.96
78_V	108_A	0.920	0.96
398_A	411_L	0.920	0.96
410_V	462_A	0.918	0.96
77_Y	105_A	0.917	0.96
430_A	467_V	0.911	0.96
451_L	468_A	0.910	0.96
58_P	88_I	0.910	0.96
431_G	474_D	0.909	0.96
371_V	408_V	0.909	0.96
63_W	132_L	0.907	0.96
27_E	38_L	0.906	0.96
391_E	394_R	0.905	0.96
17_V	427_I	0.902	0.96
23_I	27_E	0.899	0.96
53_C	57_Y	0.899	0.96
468_A	497_I	0.891	0.96
387_V	391_E	0.890	0.96
256_R	322_D	0.890	0.96
361_A	381_R	0.887	0.95
288_L	309_L	0.884	0.95
27_E	31_A	0.881	0.95
158_N	185_I	0.880	0.95
49_A	53_C	0.879	0.95
162_A	188_D	0.876	0.95
456_L	464_A	0.875	0.95
43_L	108_A	0.874	0.95
371_V	410_V	0.874	0.95
263_D	333_Q	0.873	0.95
154_I	185_I	0.870	0.95
355_D	358_N	0.870	0.95
53_C	56_A	0.869	0.95
189_H	211_Q	0.867	0.95
146_P	181_P	0.867	0.95
379_A	390_I	0.867	0.95
428_I	467_V	0.864	0.95
193_F	215_D	0.863	0.95
178_G	205_A	0.862	0.95
39_Y	104_E	0.860	0.95
394_R	411_L	0.858	0.95
377_G	380_A	0.858	0.95
169_I	175_A	0.858	0.95
476_L	485_M	0.855	0.94
350_M	370_R	0.853	0.94
323_V	452_L	0.851	0.94
173_L	204_K	0.850	0.94
49_A	165_V	0.849	0.94
92_L	117_G	0.849	0.94
416_T	462_A	0.847	0.94
61_R	131_D	0.846	0.94
282_A	450_A	0.846	0.94
166_A	185_I	0.843	0.94
39_Y	111_A	0.843	0.94
383_L	390_I	0.842	0.94
39_Y	78_V	0.841	0.94
37_T	107_L	0.838	0.94
493_T	496_R	0.835	0.94
450_A	454_Q	0.835	0.94
386_S	390_I	0.835	0.94
435_M	474_D	0.834	0.94
135_D	171_S	0.832	0.94
296_P	299_T	0.831	0.94
257_L	285_V	0.829	0.94
273_T	325_V	0.829	0.94
337_K	363_N	0.829	0.94
233_F	463_C	0.827	0.93
337_K	362_I	0.826	0.93
164_I	188_D	0.824	0.93
201_L	427_I	0.824	0.93
198_P	395_L	0.823	0.93
145_A	151_S	0.823	0.93
394_R	413_G	0.823	0.93
192_T	214_F	0.821	0.93
166_A	187_A	0.818	0.93
77_Y	92_L	0.818	0.93
207_D	246_R	0.815	0.93
50_F	82_L	0.814	0.93
186_N	208_V	0.813	0.93
52_V	215_D	0.812	0.93
472_A	476_L	0.811	0.93
280_A	494_L	0.810	0.93
256_R	320_W	0.809	0.93
50_F	53_C	0.806	0.93
24_R	176_E	0.804	0.92
220_D	223_L	0.803	0.92
419_A	425_L	0.802	0.92
152_Q	155_D	0.799	0.92
456_L	461_A	0.799	0.92
370_R	407_G	0.798	0.92
44_R	82_L	0.796	0.92
60_A	88_I	0.794	0.92
437_S	486_L	0.791	0.92
259_I	285_V	0.790	0.92
261_G	273_T	0.783	0.91
109_R	119_I	0.783	0.91
27_E	30_A	0.781	0.91
443_V	487_A	0.781	0.91
443_V	447_I	0.780	0.91
315_T	318_L	0.780	0.91
146_P	182_G	0.777	0.91
137_L	150_I	0.777	0.91
398_A	409_A	0.776	0.91
349_P	452_L	0.775	0.91
69_H	138_L	0.773	0.91
284_L	305_M	0.773	0.91
286_R	307_H	0.770	0.91
294_I	308_E	0.770	0.91
435_M	490_L	0.770	0.91
275_E	491_F	0.769	0.91
43_L	78_V	0.768	0.91
352_W	370_R	0.768	0.91
294_I	306_V	0.767	0.91
266_T	284_L	0.767	0.91
111_A	114_N	0.767	0.91
336_G	359_L	0.765	0.91
399_K	403_Q	0.765	0.91
238_L	464_A	0.763	0.90
263_D	290_R	0.763	0.90
107_L	110_E	0.762	0.90
356_A	360_L	0.761	0.90
22_D	229_K	0.760	0.90
380_A	386_S	0.760	0.90
167_V	193_F	0.756	0.90
241_W	460_D	0.754	0.90
324_V	346_F	0.754	0.90
132_L	165_V	0.753	0.90
132_L	163_P	0.753	0.90
275_E	300_A	0.751	0.90
207_D	248_T	0.750	0.90
61_R	88_I	0.749	0.90
471_A	475_V	0.749	0.90
276_A	447_I	0.746	0.89
158_N	186_N	0.745	0.89
326_I	356_A	0.745	0.89
24_R	140_T	0.744	0.89
340_L	360_L	0.744	0.89
282_A	453_G	0.742	0.89
65_V	134_V	0.739	0.89
473_A	485_M	0.738	0.89
438_G	486_L	0.737	0.89
286_R	320_W	0.737	0.89
196_L	232_R	0.737	0.89
77_Y	98_D	0.737	0.89
137_L	146_P	0.736	0.89
256_R	305_M	0.734	0.89
174_L	199_G	0.734	0.89
418_V	466_C	0.733	0.89
287_V	304_L	0.732	0.88
417_V	427_I	0.730	0.88
430_A	474_D	0.729	0.88
279_R	492_S	0.726	0.88
53_C	88_I	0.726	0.88
22_D	25_R	0.726	0.88
216_S	220_D	0.724	0.88
383_L	397_C	0.723	0.88
472_A	493_T	0.722	0.88
40_E	111_A	0.721	0.88
434_G	477_A	0.719	0.88
393_D	397_C	0.716	0.87
207_D	247_P	0.715	0.87
474_D	477_A	0.715	0.87
173_L	180_T	0.714	0.87
55_S	213_H	0.713	0.87
56_A	165_V	0.713	0.87
484_G	495_Q	0.711	0.87
267_A	293_N	0.711	0.87
204_K	248_T	0.711	0.87
297_L	301_R	0.710	0.87
163_P	189_H	0.710	0.87
324_V	343_V	0.707	0.87
249_S	253_D	0.707	0.87
431_G	470_G	0.706	0.87
81_R	108_A	0.705	0.87
194_I	217_L	0.704	0.86
77_Y	109_R	0.702	0.86
415_G	427_I	0.701	0.86
259_I	325_V	0.701	0.86
383_L	405_Y	0.699	0.86
144_Q	181_P	0.699	0.86
194_I	224_A	0.697	0.86
271_R	298_L	0.697	0.86
394_R	415_G	0.695	0.86
31_A	36_L	0.694	0.86
258_V	314_L	0.693	0.86
377_G	387_V	0.692	0.86
95_Q	150_I	0.691	0.85
432_N	477_A	0.691	0.85
458_P	462_A	0.691	0.85
458_P	461_A	0.689	0.85
44_R	47_E	0.687	0.85
48_A	51_Q	0.684	0.85
271_R	301_R	0.682	0.85
416_T	469_H	0.682	0.85
29_E	34_L	0.682	0.85
43_L	111_A	0.681	0.85
27_E	140_T	0.680	0.85
322_D	453_G	0.679	0.84
352_W	360_L	0.679	0.84
110_E	113_L	0.679	0.84
420_A	424_A	0.678	0.84
138_L	146_P	0.677	0.84
36_L	220_D	0.676	0.84
29_E	226_Q	0.675	0.84
418_V	426_G	0.675	0.84
408_V	458_P	0.675	0.84
430_A	471_A	0.674	0.84
419_A	423_D	0.671	0.84
455_K	462_A	0.671	0.84
230_I	425_L	0.669	0.84
161_P	164_I	0.669	0.84
260_I	326_I	0.668	0.84
170_P	187_A	0.664	0.83
96_E	100_P	0.664	0.83
65_V	90_V	0.664	0.83
385_C	390_I	0.661	0.83
475_V	478_A	0.660	0.83
142_L	182_G	0.659	0.83
98_D	109_R	0.659	0.83
451_L	461_A	0.658	0.83
326_I	330_L	0.656	0.82
53_C	63_W	0.656	0.82
21_D	176_E	0.656	0.82
460_D	463_C	0.656	0.82
265_G	305_M	0.655	0.82
454_Q	483_R	0.654	0.82
63_W	83_A	0.654	0.82
39_Y	43_L	0.653	0.82
376_P	387_V	0.653	0.82
451_L	465_G	0.653	0.82
395_L	427_I	0.652	0.82
395_L	417_V	0.650	0.82
380_A	385_C	0.648	0.82
259_I	449_G	0.648	0.82
376_P	413_G	0.646	0.81
249_S	436_A	0.645	0.81
337_K	359_L	0.641	0.81
231_Q	424_A	0.641	0.81
402_V	406_G	0.641	0.81
380_A	387_V	0.638	0.81
112_W	115_A	0.633	0.80
300_A	304_L	0.632	0.80
170_P	200_L	0.631	0.80
471_A	497_I	0.630	0.80
448_I	461_A	0.629	0.80
26_G	223_L	0.629	0.80
347_R	369_N	0.626	0.79
432_N	435_M	0.625	0.79
64_L	127_P	0.624	0.79
408_V	459_Y	0.624	0.79
133_I	162_A	0.624	0.79
191_I	213_H	0.622	0.79
267_A	302_P	0.621	0.79
286_R	321_A	0.616	0.78
67_C	92_L	0.615	0.78
428_I	474_D	0.613	0.78
490_L	493_T	0.613	0.78
289_T	306_V	0.613	0.78
264_H	292_E	0.613	0.78
63_W	79_V	0.612	0.78
81_R	111_A	0.610	0.78
233_F	237_Q	0.610	0.78
395_L	399_K	0.610	0.78
18_W	22_D	0.606	0.77
31_A	39_Y	0.606	0.77
246_R	249_S	0.605	0.77
325_V	328_P	0.604	0.77
450_A	453_G	0.604	0.77
104_E	107_L	0.603	0.77
30_A	220_D	0.602	0.77
256_R	321_A	0.602	0.77
354_A	358_N	0.602	0.77
323_V	349_P	0.601	0.77
397_C	401_L	0.600	0.76
288_L	314_L	0.600	0.76
24_R	175_A	0.600	0.76
179_A	392_S	0.599	0.76
468_A	498_V	0.599	0.76
94_A	105_A	0.598	0.76
426_G	460_D	0.598	0.76
408_V	416_T	0.598	0.76
98_D	113_L	0.596	0.76
398_A	410_V	0.596	0.76
379_A	409_A	0.595	0.76
315_T	342_K	0.593	0.76
311_M	315_T	0.593	0.76
390_I	411_L	0.592	0.76
127_P	156_H	0.591	0.75
273_T	445_S	0.590	0.75
49_A	52_V	0.589	0.75
57_Y	189_H	0.589	0.75
303_E	487_A	0.589	0.75
303_E	437_S	0.589	0.75
144_Q	148_E	0.588	0.75
51_Q	215_D	0.588	0.75
271_R	275_E	0.587	0.75
203_G	207_D	0.587	0.75
330_L	336_G	0.584	0.75
247_P	433_A	0.582	0.74
285_V	449_G	0.582	0.74
258_V	317_S	0.579	0.74
27_E	37_T	0.579	0.74
29_E	32_D	0.577	0.74
143_R	174_L	0.577	0.74
187_A	210_G	0.576	0.74
198_P	230_I	0.576	0.74
235_A	467_V	0.576	0.74
278_L	285_V	0.576	0.74
260_I	330_L	0.576	0.74
336_G	339_A	0.575	0.73
85_A	115_A	0.574	0.73
20_A	140_T	0.573	0.73
110_E	114_N	0.573	0.73
38_L	103_E	0.573	0.73
177_T	199_G	0.571	0.73
312_D	315_T	0.570	0.73
263_D	266_T	0.570	0.73
278_L	305_M	0.570	0.73
451_L	454_Q	0.570	0.73
431_G	435_M	0.568	0.72
24_R	27_E	0.568	0.72
338_K	341_Q	0.568	0.72
74_G	104_E	0.567	0.72
138_L	154_I	0.566	0.72
64_L	133_I	0.566	0.72
322_D	348_K	0.565	0.72
276_A	438_G	0.565	0.72
156_H	160_H	0.565	0.72
485_M	489_D	0.563	0.72
148_E	154_I	0.562	0.72
252_G	256_R	0.561	0.72
402_V	407_G	0.560	0.71
342_K	345_N	0.560	0.71
241_W	464_A	0.560	0.71
477_A	485_M	0.559	0.71
21_D	24_R	0.558	0.71
298_L	302_P	0.557	0.71
480_F	492_S	0.557	0.71
491_F	494_L	0.555	0.71
468_A	494_L	0.555	0.71
142_L	148_E	0.554	0.71
111_A	115_A	0.552	0.70
142_L	146_P	0.551	0.70
25_R	226_Q	0.550	0.70
437_S	473_A	0.550	0.70
184_V	199_G	0.550	0.70
56_A	213_H	0.548	0.70
133_I	160_H	0.548	0.70
360_L	372_I	0.548	0.70
20_A	24_R	0.547	0.70
153_L	156_H	0.547	0.70
288_L	317_S	0.546	0.70
50_F	54_R	0.546	0.70
79_V	165_V	0.545	0.69
410_V	465_G	0.545	0.69
351_L	371_V	0.545	0.69
438_G	490_L	0.544	0.69
488_T	491_F	0.544	0.69
142_L	171_S	0.544	0.69
283_G	469_H	0.544	0.69
51_Q	86_V	0.541	0.69
356_A	359_L	0.541	0.69
82_L	85_A	0.540	0.69
185_I	188_D	0.539	0.69
459_Y	462_A	0.538	0.68
235_A	471_A	0.537	0.68
17_V	199_G	0.537	0.68
56_A	191_I	0.535	0.68
146_P	151_S	0.534	0.68
275_E	488_T	0.534	0.68
160_H	164_I	0.534	0.68
285_V	304_L	0.533	0.68
379_A	419_A	0.533	0.68
472_A	497_I	0.532	0.68
202_T	205_A	0.532	0.68
248_T	391_E	0.531	0.67
232_R	430_A	0.531	0.67
252_G	284_L	0.531	0.67
293_N	298_L	0.531	0.67
434_G	481_G	0.530	0.67
291_S	308_E	0.530	0.67
296_P	300_A	0.529	0.67
229_K	395_L	0.529	0.67
26_G	219_L	0.528	0.67
107_L	111_A	0.528	0.67
278_L	304_L	0.527	0.67
343_V	346_F	0.527	0.67
398_A	425_L	0.526	0.67
30_A	219_L	0.526	0.67
150_I	153_L	0.526	0.67
428_I	431_G	0.526	0.67
69_H	147_R	0.525	0.67
470_G	473_A	0.525	0.67
158_N	164_I	0.525	0.67
338_K	342_K	0.521	0.66
387_V	390_I	0.521	0.66
57_Y	132_L	0.521	0.66
278_L	303_E	0.520	0.66
175_A	199_G	0.520	0.66
23_I	217_L	0.519	0.66
252_G	438_G	0.518	0.66
23_I	194_I	0.517	0.65
43_L	82_L	0.516	0.65
475_V	496_R	0.516	0.65
288_L	308_E	0.515	0.65
74_G	105_A	0.514	0.65
108_A	115_A	0.514	0.65
284_L	320_W	0.512	0.65
267_A	296_P	0.511	0.64
273_T	328_P	0.511	0.64
494_L	498_V	0.511	0.64
78_V	82_L	0.510	0.64
369_N	452_L	0.510	0.64
66_L	93_L	0.510	0.64
334_E	337_K	0.509	0.64
292_E	295_A	0.509	0.64
143_R	147_R	0.508	0.64
154_I	164_I	0.508	0.64
27_E	220_D	0.508	0.64
344_E	350_M	0.507	0.64
314_L	317_S	0.507	0.64
233_F	238_L	0.507	0.64
261_G	269_A	0.506	0.64
390_I	393_D	0.505	0.64
173_L	209_T	0.505	0.64
111_A	117_G	0.505	0.64
160_H	185_I	0.504	0.63
286_R	317_S	0.504	0.63
476_L	491_F	0.504	0.63
198_P	417_V	0.503	0.63
256_R	266_T	0.502	0.63
324_V	348_K	0.502	0.63
347_R	367_R	0.501	0.63
174_L	178_G	0.501	0.63
112_W	116_G	0.501	0.63
233_F	426_G	0.500	0.63
305_M	438_G	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3rssA	4	0.9282	100	0.3	Contact Map
3k5wA	4	0.8777	100	0.318	Contact Map
1jztA	2	0.4272	100	0.657	Contact Map
3bgkA	3	0.5204	100	0.664	Contact Map
2o8nA	2	0.4311	100	0.667	Contact Map
3rpzA	3	0.534	100	0.668	Contact Map
2r3bA	3	0.5379	100	0.687	Contact Map
3d3kA	2	0.4311	100	0.689	Contact Map
3d3jA	2	0.4233	100	0.69	Contact Map
3nl6A	4	0.8369	100	0.791	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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