GREMLIN Database
DJLA - DnaJ-like protein DjlA
UniProt: P31680 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11570
Length: 271 (245)
Sequences: 942 (664)
Seq/√Len: 42.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
217_D220_T7.3471.00
216_D221_I5.4991.00
218_A268_K5.2241.00
69_K76_D4.0801.00
143_D150_E4.0021.00
216_D220_T3.9801.00
102_R105_K3.6151.00
6_K34_D3.4741.00
6_K31_H3.0441.00
229_M254_A2.8991.00
218_A221_I2.8191.00
204_E214_P2.6641.00
203_L264_I2.6231.00
164_S167_Q2.5501.00
247_M251_K2.5361.00
251_K255_Q2.5081.00
212_V216_D2.4331.00
71_R74_E2.3331.00
244_P248_E2.2721.00
58_T136_Q2.2381.00
61_V132_F2.2081.00
63_G104_G2.0540.99
22_G26_G2.0430.99
226_R250_A2.0320.99
25_L29_I2.0150.99
26_G30_G1.9900.99
30_G34_D1.9720.99
61_V136_Q1.9350.99
207_C268_K1.9260.99
8_I12_V1.8640.99
230_S236_K1.8430.98
12_V15_L1.8220.98
10_V28_L1.8200.98
112_R156_V1.7950.98
74_E78_H1.7770.98
26_G34_D1.7750.98
134_E232_H1.7740.98
10_V27_L1.7700.98
5_G33_F1.7110.97
137_I168_F1.6900.97
81_S94_R1.6500.97
212_V221_I1.6430.97
5_G9_G1.5960.96
132_F136_Q1.5950.96
76_D207_C1.5810.96
213_K216_D1.5600.96
239_A247_M1.5370.95
130_R167_Q1.5060.95
222_K226_R1.4720.94
89_L97_A1.4690.94
68_S250_A1.4660.94
133_L154_L1.4630.94
224_A227_K1.4580.94
203_L267_Q1.4400.93
211_G231_E1.4130.92
112_R160_E1.4070.92
207_C264_I1.3920.92
31_H34_D1.3830.92
59_F63_G1.3720.91
5_G31_H1.3640.91
241_G247_M1.3590.91
61_V111_L1.3580.91
168_F172_L1.3520.91
13_A26_G1.3380.90
165_R169_D1.3360.90
17_G87_M1.3360.90
62_M136_Q1.3230.90
99_N103_V1.3180.90
64_H153_V1.3160.89
95_T99_N1.2790.88
167_Q170_Q1.2130.85
248_E252_Q1.2110.85
254_A258_Q1.2050.85
13_A22_G1.1820.84
146_L150_E1.1770.83
33_F36_A1.1730.83
143_D146_L1.1720.83
11_A19_G1.1690.83
236_K241_G1.1650.83
126_F167_Q1.1610.83
243_P246_M1.1570.82
69_K143_D1.1530.82
69_K207_C1.1390.81
158_A168_F1.1370.81
14_L25_L1.1090.80
19_G24_V1.1070.79
81_S91_G1.1050.79
104_G254_A1.1000.79
116_R160_E1.0950.79
219_T223_R1.0950.79
59_F84_M1.0860.78
264_I268_K1.0860.78
246_M249_M1.0790.78
80_A139_A1.0780.78
77_I80_A1.0650.77
76_D142_A1.0520.76
203_L207_C1.0510.76
59_F97_A1.0470.76
151_R155_Y1.0420.75
9_G17_G1.0330.75
63_G97_A1.0240.74
136_Q157_I1.0210.74
227_K258_Q1.0200.74
254_A259_Q1.0180.73
38_S42_A1.0160.73
221_I259_Q1.0020.72
92_A95_T0.9940.72
112_R142_A0.9890.71
95_T98_Q0.9880.71
207_C218_A0.9880.71
156_V159_E0.9870.71
23_V26_G0.9680.70
14_L21_W0.9670.70
25_L171_F0.9670.70
173_R208_N0.9630.69
221_I264_I0.9620.69
248_E251_K0.9580.69
149_N152_A0.9540.68
84_M89_L0.9380.67
24_V48_R0.9210.66
212_V220_T0.9190.66
215_T223_R0.9150.65
21_W28_L0.9140.65
59_F104_G0.9060.64
125_R128_L0.9020.64
62_M135_I0.9000.64
22_G30_G0.9000.64
126_F129_I0.8980.64
105_K209_V0.8970.64
63_G229_M0.8930.63
111_L161_L0.8930.63
59_F89_L0.8900.63
15_L33_F0.8890.63
63_G115_M0.8830.62
140_A143_D0.8760.62
76_D143_D0.8750.62
232_H257_I0.8730.62
237_L251_K0.8700.61
14_L123_F0.8610.60
212_V224_A0.8600.60
137_I154_L0.8560.60
63_G100_A0.8550.60
19_G100_A0.8550.60
119_R162_G0.8520.60
217_D254_A0.8460.59
90_H93_S0.8450.59
263_L267_Q0.8370.58
15_L28_L0.8310.58
75_A78_H0.8290.58
81_S98_Q0.8270.57
59_F101_F0.8250.57
104_G246_M0.8190.57
63_G80_A0.8160.56
222_K261_Y0.8160.56
6_K27_L0.8150.56
61_V139_A0.8110.56
224_A250_A0.8100.56
11_A21_W0.8100.56
31_H35_K0.8090.56
77_I84_M0.8080.56
85_D94_R0.8050.55
69_K100_A0.8040.55
7_I32_M0.8030.55
10_V19_G0.8010.55
243_P249_M0.8000.55
67_K105_K0.8000.55
252_Q256_E0.7910.54
228_L257_I0.7900.54
166_A253_K0.7880.54
118_F122_C0.7840.53
45_A92_A0.7840.53
77_I105_K0.7840.53
141_F146_L0.7830.53
80_A232_H0.7810.53
57_T118_F0.7790.53
232_H247_M0.7750.52
5_G34_D0.7750.52
131_M240_K0.7750.52
72_V105_K0.7730.52
67_K77_I0.7720.52
10_V13_A0.7700.52
115_M161_L0.7700.52
11_A15_L0.7680.52
63_G254_A0.7650.52
124_G240_K0.7640.51
81_S85_D0.7600.51
84_M98_Q0.7580.51
101_F105_K0.7570.51
159_E165_R0.7570.51
156_V160_E0.7560.51
59_F258_Q0.7560.51
65_L153_V0.7560.51
67_K72_V0.7540.50
64_H115_M0.7520.50
89_L104_G0.7520.50
237_L241_G0.7510.50
58_T62_M0.7490.50
97_A104_G0.7370.49
9_G30_G0.7350.49
67_K250_A0.7270.48
77_I98_Q0.7250.48
153_V157_I0.7240.48
80_A104_G0.7230.48
238_V247_M0.7230.48
49_E121_V0.7200.47
9_G26_G0.7190.47
237_L242_L0.7160.47
78_H82_Q0.7110.46
236_K250_A0.7100.46
64_H104_G0.7090.46
9_G242_L0.7060.46
100_A255_Q0.6970.45
11_A17_G0.6920.45
69_K175_M0.6910.45
59_F236_K0.6910.45
8_I168_F0.6890.44
85_D91_G0.6880.44
151_R244_P0.6880.44
104_G115_M0.6860.44
43_W120_S0.6850.44
54_F250_A0.6840.44
104_G114_K0.6820.44
134_E211_G0.6820.44
266_Q269_G0.6790.43
229_M258_Q0.6780.43
228_L231_E0.6780.43
88_N156_V0.6750.43
79_I83_L0.6750.43
66_T104_G0.6730.43
67_K70_G0.6730.43
62_M94_R0.6690.43
128_L243_P0.6680.42
237_L247_M0.6680.42
46_N256_E0.6680.42
145_S148_P0.6670.42
114_K221_I0.6670.42
11_A14_L0.6650.42
169_D252_Q0.6650.42
222_K269_G0.6640.42
9_G13_A0.6600.42
69_K150_E0.6570.41
249_M256_E0.6560.41
24_V197_A0.6560.41
54_F243_P0.6490.41
102_R132_F0.6460.40
222_K250_A0.6450.40
75_A253_K0.6450.40
70_G76_D0.6450.40
60_E253_K0.6440.40
211_G256_E0.6430.40
212_V228_L0.6430.40
70_G222_K0.6410.40
211_G224_A0.6410.40
64_H111_L0.6350.39
11_A114_K0.6340.39
111_L157_I0.6330.39
24_V45_A0.6320.39
11_A108_N0.6290.39
145_S266_Q0.6280.39
203_L206_A0.6280.39
242_L249_M0.6260.39
141_F172_L0.6260.39
6_K33_F0.6250.38
242_L246_M0.6220.38
11_A123_F0.6220.38
202_T205_D0.6200.38
232_H250_A0.6180.38
59_F229_M0.6170.38
17_G23_V0.6170.38
133_L151_R0.6160.38
31_H146_L0.6160.38
237_L246_M0.6160.38
226_R231_E0.6150.38
52_A96_A0.6140.38
141_F176_Q0.6130.37
136_Q150_E0.6130.37
251_K258_Q0.6120.37
207_C222_K0.6110.37
92_A267_Q0.6080.37
206_A263_L0.6070.37
76_D136_Q0.6070.37
168_F245_E0.6050.37
80_A109_Y0.6040.37
87_M90_H0.6020.36
29_I133_L0.6010.36
76_D258_Q0.5980.36
210_L233_H0.5930.36
91_G95_T0.5870.35
168_F171_F0.5840.35
97_A241_G0.5810.35
12_V128_L0.5810.35
94_R97_A0.5800.35
17_G21_W0.5790.34
78_H81_S0.5790.34
115_M160_E0.5770.34
223_R227_K0.5740.34
86_R148_P0.5730.34
105_K132_F0.5730.34
12_V33_F0.5720.34
242_L245_E0.5720.34
24_V133_L0.5710.34
227_K231_E0.5710.34
88_N163_I0.5710.34
63_G109_Y0.5700.34
210_L235_D0.5690.34
104_G229_M0.5680.34
120_S213_K0.5640.33
217_D268_K0.5640.33
58_T246_M0.5630.33
55_F206_A0.5600.33
149_N266_Q0.5600.33
13_A23_V0.5560.33
9_G22_G0.5520.32
98_Q258_Q0.5510.32
148_P152_A0.5490.32
201_P204_E0.5470.32
21_W25_L0.5470.32
149_N205_D0.5460.32
14_L19_G0.5440.32
216_D225_Y0.5440.32
87_M139_A0.5440.32
42_A45_A0.5430.31
126_F163_I0.5420.31
63_G89_L0.5400.31
35_K40_K0.5400.31
100_A259_Q0.5380.31
152_A169_D0.5380.31
223_R229_M0.5330.31
59_F62_M0.5300.30
25_L28_L0.5290.30
205_D208_N0.5290.30
7_I11_A0.5280.30
11_A32_M0.5270.30
140_A150_E0.5260.30
253_K269_G0.5230.30
62_M83_L0.5220.30
95_T201_P0.5220.30
21_W100_A0.5220.30
57_T68_S0.5190.30
96_A133_L0.5190.30
16_M198_Q0.5190.30
261_Y265_K0.5190.30
9_G23_V0.5190.30
43_W220_T0.5180.29
108_N113_E0.5180.29
28_L35_K0.5170.29
77_I81_S0.5160.29
74_E81_S0.5130.29
65_L121_V0.5130.29
84_M97_A0.5110.29
109_Y114_K0.5110.29
129_I163_I0.5080.29
155_Y168_F0.5080.29
155_Y169_D0.5070.29
73_T243_P0.5070.29
80_A84_M0.5070.29
28_L266_Q0.5060.29
9_G14_L0.5060.29
69_K258_Q0.5050.28
69_K240_K0.5050.28
155_Y244_P0.5050.28
242_L247_M0.5040.28
73_T244_P0.5040.28
60_E221_I0.5020.28
12_V40_K0.5020.28
158_A217_D0.5010.28
63_G101_F0.5000.28
132_F161_L0.5000.28
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ag7A 1 0.3838 99.8 0.747 Contact Map
2jxuA 1 0.5424 99.7 0.763 Contact Map
2h5nA 5 0.4908 99.7 0.77 Contact Map
2ou3A 2 0.5904 99.7 0.778 Contact Map
3lz8A 2 0 99.6 0.781 Contact Map
4wb7A 1 0.2251 99.6 0.782 Contact Map
1wjzA 1 0.3026 99.6 0.783 Contact Map
3apoA 1 0.1328 99.6 0.785 Contact Map
4j80A 2 0.2325 99.6 0.788 Contact Map
3apqA 1 0.2288 99.6 0.789 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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