YIDK - ECOLI - GREMLIN Contacts

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YIDK - Uncharacterized symporter YidK

UniProt:	P31448	Sequences: MNSLQILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKAPVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRGIATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHGAAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFMQGIEQLTTVHAEKLNSIGGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLAEGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPMVGFFGAVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVLVAPWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITINYLVKFDFHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDMKPWKNVKIASIGILFAMIGVYAGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSWRHRHDPAVTFTPDGKDSL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11706
Length:	571 (469)
Sequences:	11238 (7114)
Seq/√Len:	328.5

ECOLI - YIDK ACTP PANF PUTP
BACSU - YWCA OPUE YODF YCGO YHJB
HALSA - Q9HR16 Q9HP63
SULSO - Q7LX83 Q97VX6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
442_I	474_V	6.117	1.00
370_E	373_Q	4.395	1.00
431_I	475_M	4.030	1.00
274_S	277_E	3.957	1.00
366_N	373_Q	3.930	1.00
18_V	22_W	3.623	1.00
442_I	470_I	3.419	1.00
219_Q	222_E	3.353	1.00
175_I	386_A	3.335	1.00
438_V	478_I	3.249	1.00
476_L	480_F	3.200	1.00
208_G	302_I	3.192	1.00
439_A	475_M	3.172	1.00
361_Y	369_A	3.156	1.00
446_S	470_I	3.151	1.00
478_I	482_K	3.109	1.00
206_V	210_I	3.102	1.00
474_V	478_I	3.092	1.00
432_P	482_K	3.030	1.00
372_Q	376_T	2.957	1.00
435_A	479_G	2.849	1.00
434_L	482_K	2.781	1.00
424_M	475_M	2.673	1.00
110_E	118_R	2.673	1.00
162_A	165_L	2.663	1.00
376_T	380_K	2.648	1.00
171_G	390_V	2.592	1.00
303_A	316_A	2.509	1.00
11_G	15_L	2.498	1.00
183_L	271_A	2.427	1.00
33_Q	40_R	2.413	1.00
42_L	187_A	2.400	1.00
380_K	384_F	2.344	1.00
438_V	474_V	2.283	1.00
273_K	277_E	2.221	1.00
108_F	425_G	2.190	1.00
432_P	435_A	2.189	1.00
66_G	314_D	2.134	1.00
34_G	39_G	2.102	1.00
369_A	373_Q	2.098	1.00
219_Q	223_Q	2.071	1.00
222_E	226_T	2.056	1.00
421_I	436_A	2.047	1.00
434_L	438_V	2.042	1.00
113_Y	431_I	2.038	1.00
168_I	172_L	2.031	1.00
428_F	431_I	2.025	1.00
14_L	18_V	1.998	1.00
58_T	140_S	1.983	1.00
445_I	449_T	1.966	1.00
387_I	391_L	1.965	1.00
435_A	478_I	1.945	1.00
432_P	479_G	1.943	1.00
200_G	336_V	1.925	1.00
202_L	206_V	1.892	1.00
358_M	362_R	1.886	1.00
473_V	477_V	1.856	1.00
356_F	381_F	1.847	1.00
222_E	225_T	1.841	1.00
12_F	16_V	1.833	1.00
361_Y	377_V	1.831	1.00
424_M	472_V	1.819	1.00
428_F	480_F	1.816	1.00
430_R	480_F	1.792	1.00
181_G	185_A	1.785	1.00
307_Y	323_N	1.781	1.00
233_N	236_G	1.781	1.00
366_N	369_A	1.770	1.00
46_V	191_S	1.769	1.00
428_F	476_L	1.758	1.00
37_L	40_R	1.758	1.00
376_T	379_R	1.752	1.00
102_I	111_E	1.743	1.00
276_A	280_K	1.739	1.00
362_R	374_L	1.726	1.00
276_A	279_Q	1.725	1.00
277_E	280_K	1.721	1.00
19_I	192_I	1.721	1.00
435_A	439_A	1.695	1.00
361_Y	366_N	1.691	1.00
110_E	115_K	1.685	1.00
174_G	345_F	1.685	1.00
228_H	231_K	1.666	1.00
356_F	360_I	1.645	1.00
230_E	233_N	1.635	1.00
430_R	483_P	1.627	1.00
319_T	323_N	1.619	1.00
231_K	235_I	1.615	1.00
438_V	442_I	1.606	1.00
331_G	335_A	1.596	1.00
6_I	10_V	1.578	1.00
190_D	268_R	1.544	1.00
107_D	359_G	1.539	1.00
217_F	221_I	1.523	1.00
44_A	277_E	1.519	1.00
49_A	191_S	1.516	1.00
164_W	394_P	1.508	1.00
373_Q	376_T	1.482	1.00
218_M	222_E	1.471	1.00
15_L	19_I	1.471	1.00
120_I	437_K	1.466	1.00
349_L	386_A	1.463	1.00
47_I	272_S	1.463	1.00
172_L	176_L	1.458	1.00
432_P	483_P	1.448	1.00
142_A	167_V	1.445	1.00
223_Q	226_T	1.438	1.00
93_F	423_I	1.433	1.00
442_I	446_S	1.429	1.00
221_I	224_L	1.427	1.00
116_T	437_K	1.421	1.00
231_K	234_S	1.418	1.00
112_R	425_G	1.414	1.00
361_Y	373_Q	1.412	1.00
469_C	473_V	1.411	1.00
114_D	433_A	1.402	1.00
352_A	385_I	1.392	1.00
218_M	221_I	1.385	1.00
123_F	360_I	1.385	1.00
143_L	312_K	1.384	1.00
16_V	192_I	1.375	1.00
365_I	369_A	1.370	1.00
167_V	390_V	1.344	1.00
10_V	14_L	1.333	1.00
369_A	374_L	1.331	1.00
31_S	34_G	1.313	1.00
124_C	444_I	1.312	1.00
171_G	386_A	1.308	1.00
107_D	358_M	1.292	1.00
446_S	474_V	1.289	1.00
110_E	363_R	1.288	1.00
165_L	169_L	1.283	1.00
141_G	170_L	1.281	1.00
36_F	378_G	1.274	1.00
118_R	359_G	1.255	1.00
174_G	342_I	1.240	1.00
5_Q	328_P	1.238	1.00
375_V	379_R	1.238	1.00
470_I	474_V	1.235	1.00
356_F	361_Y	1.230	1.00
189_A	346_N	1.229	1.00
54_T	347_G	1.225	1.00
108_F	112_R	1.223	1.00
220_G	224_L	1.221	1.00
50_S	347_G	1.219	1.00
165_L	168_I	1.217	1.00
434_L	478_I	1.215	1.00
38_A	183_L	1.214	1.00
104_T	354_T	1.211	1.00
15_L	192_I	1.209	1.00
190_D	346_N	1.207	1.00
123_F	127_I	1.204	1.00
22_W	26_K	1.202	1.00
373_Q	377_V	1.201	1.00
168_I	390_V	1.195	1.00
99_K	275_L	1.189	1.00
430_R	484_R	1.189	1.00
138_L	171_G	1.187	1.00
115_K	119_I	1.187	1.00
449_T	453_L	1.186	1.00
117_T	437_K	1.181	1.00
432_P	478_I	1.168	1.00
164_W	168_I	1.166	1.00
27_T	34_G	1.158	1.00
168_I	394_P	1.157	1.00
68_A	75_V	1.155	1.00
48_A	284_L	1.150	1.00
76_M	80_V	1.147	1.00
221_I	225_T	1.143	1.00
177_Y	342_I	1.142	1.00
469_C	472_V	1.140	1.00
232_L	236_G	1.139	1.00
310_L	313_A	1.137	1.00
234_S	237_G	1.133	1.00
472_V	476_L	1.125	1.00
7_L	11_G	1.124	1.00
199_I	203_M	1.123	1.00
38_A	42_L	1.118	1.00
433_A	437_K	1.117	1.00
378_G	382_G	1.113	1.00
195_I	199_I	1.111	1.00
229_A	232_L	1.108	1.00
146_N	163_I	1.103	1.00
117_T	436_A	1.102	1.00
174_G	346_N	1.100	1.00
211_A	306_L	1.099	1.00
193_N	346_N	1.098	1.00
431_I	479_G	1.093	1.00
161_A	166_L	1.088	1.00
357_S	378_G	1.080	1.00
119_I	364_I	1.080	1.00
439_A	443_G	1.078	1.00
431_I	435_A	1.078	1.00
220_G	223_Q	1.074	1.00
470_I	473_V	1.072	1.00
33_Q	101_G	1.070	1.00
7_L	10_V	1.068	1.00
134_L	389_S	1.063	1.00
474_V	477_V	1.062	1.00
121_I	440_M	1.057	1.00
116_T	433_A	1.056	1.00
430_R	485_A	1.054	1.00
357_S	377_V	1.047	1.00
179_V	383_F	1.044	1.00
424_M	431_I	1.044	1.00
120_I	440_M	1.041	1.00
12_F	342_I	1.040	1.00
138_L	167_V	1.039	1.00
235_I	238_P	1.039	1.00
425_G	436_A	1.037	1.00
381_F	384_F	1.037	1.00
17_A	20_T	1.032	1.00
149_F	160_G	1.031	1.00
361_Y	365_I	1.030	1.00
417_P	471_N	1.027	1.00
120_I	441_G	1.023	1.00
244_I	247_A	1.023	1.00
439_A	471_N	1.018	1.00
321_V	333_F	1.017	1.00
434_L	481_I	1.014	1.00
203_M	207_F	1.013	1.00
371_P	374_L	1.012	1.00
377_V	381_F	1.011	1.00
44_A	48_A	1.010	1.00
190_D	347_G	1.009	1.00
225_T	229_A	1.009	1.00
421_I	440_M	1.008	1.00
464_L	468_F	1.001	1.00
52_M	288_L	1.001	1.00
109_L	117_T	0.995	1.00
212_M	220_G	0.992	1.00
54_T	190_D	0.990	1.00
15_L	18_V	0.988	1.00
124_C	440_M	0.982	1.00
88_F	92_I	0.982	1.00
115_K	363_R	0.981	1.00
126_L	356_F	0.978	1.00
486_T	489_T	0.972	1.00
428_F	479_G	0.963	1.00
214_K	219_Q	0.960	1.00
228_H	235_I	0.960	1.00
177_Y	346_N	0.959	1.00
36_F	354_T	0.957	1.00
205_P	295_V	0.954	1.00
318_P	321_V	0.951	1.00
424_M	476_L	0.947	1.00
203_M	329_M	0.946	1.00
98_L	275_L	0.938	1.00
223_Q	305_H	0.937	1.00
113_Y	475_M	0.935	1.00
146_N	160_G	0.931	1.00
484_R	490_F	0.931	1.00
220_G	302_I	0.929	1.00
443_G	447_Y	0.928	1.00
207_F	211_A	0.927	1.00
21_W	25_R	0.926	1.00
100_R	111_E	0.924	1.00
356_F	385_I	0.924	1.00
350_N	353_S	0.922	1.00
17_A	21_W	0.919	1.00
112_R	428_F	0.918	1.00
57_S	133_F	0.918	1.00
50_S	53_L	0.917	1.00
201_G	296_L	0.915	1.00
302_I	306_L	0.914	1.00
193_N	339_G	0.914	1.00
487_P	490_F	0.913	1.00
443_G	471_N	0.907	1.00
126_L	352_A	0.905	1.00
81_T	85_T	0.904	1.00
83_A	290_M	0.904	1.00
214_K	217_F	0.904	1.00
312_K	315_M	0.903	1.00
369_A	377_V	0.903	1.00
53_L	268_R	0.898	1.00
403_L	406_W	0.895	1.00
449_T	452_Y	0.894	1.00
70_K	313_A	0.893	1.00
343_S	346_N	0.891	1.00
113_Y	425_G	0.890	1.00
135_P	392_V	0.888	1.00
232_L	235_I	0.879	1.00
94_L	98_L	0.877	1.00
44_A	280_K	0.876	1.00
450_I	466_C	0.876	1.00
319_T	322_N	0.874	1.00
109_L	121_I	0.872	1.00
46_V	187_A	0.870	1.00
466_C	469_C	0.870	1.00
50_S	268_R	0.870	1.00
12_F	339_G	0.868	1.00
353_S	357_S	0.867	1.00
303_A	320_L	0.865	1.00
189_A	193_N	0.862	1.00
228_H	234_S	0.861	1.00
58_T	341_V	0.860	1.00
421_I	471_N	0.860	1.00
4_L	7_L	0.855	1.00
43_K	277_E	0.854	1.00
50_S	187_A	0.852	1.00
83_A	286_A	0.851	1.00
409_Q	451_N	0.849	1.00
435_A	438_V	0.849	1.00
471_N	475_M	0.848	1.00
257_F	262_N	0.847	1.00
476_L	479_G	0.846	1.00
228_H	232_L	0.846	1.00
9_F	13_T	0.843	1.00
133_F	262_N	0.843	1.00
5_Q	330_V	0.839	1.00
68_A	301_L	0.839	1.00
23_K	27_T	0.836	1.00
361_Y	364_I	0.836	1.00
458_F	466_C	0.836	1.00
167_V	393_A	0.834	1.00
420_T	472_V	0.834	1.00
232_L	238_P	0.832	1.00
387_I	390_V	0.831	1.00
67_Q	71_S	0.830	1.00
94_L	97_Y	0.828	1.00
249_T	252_I	0.821	1.00
384_F	388_V	0.820	1.00
149_F	161_A	0.817	1.00
321_V	330_V	0.816	1.00
220_G	225_T	0.815	1.00
177_Y	193_N	0.813	1.00
21_W	180_I	0.813	1.00
18_V	21_W	0.812	1.00
477_V	481_I	0.812	1.00
27_T	30_G	0.811	1.00
254_V	258_Y	0.810	1.00
186_M	189_A	0.808	1.00
299_P	320_L	0.808	1.00
204_V	208_G	0.807	1.00
406_W	410_L	0.806	1.00
429_P	490_F	0.805	1.00
49_A	194_G	0.805	1.00
177_Y	343_S	0.804	1.00
362_R	367_Q	0.804	1.00
442_I	478_I	0.804	1.00
119_I	360_I	0.803	1.00
13_T	16_V	0.801	1.00
437_K	441_G	0.800	1.00
229_A	233_N	0.800	1.00
69_Y	310_L	0.795	1.00
211_A	324_V	0.795	1.00
253_L	257_F	0.794	1.00
91_L	283_L	0.793	1.00
485_A	489_T	0.792	1.00
208_G	211_A	0.791	1.00
50_S	54_T	0.789	1.00
477_V	480_F	0.787	1.00
233_N	237_G	0.786	1.00
12_F	20_T	0.785	1.00
61_L	201_G	0.784	1.00
4_L	8_S	0.783	1.00
38_A	271_A	0.783	1.00
87_I	91_L	0.782	1.00
432_P	484_R	0.781	1.00
283_L	287_V	0.780	1.00
204_V	317_Y	0.778	1.00
434_L	483_P	0.778	1.00
231_K	237_G	0.777	1.00
44_A	284_L	0.777	1.00
428_F	435_A	0.775	1.00
287_V	291_L	0.773	1.00
272_S	278_G	0.772	1.00
73_M	301_L	0.772	1.00
30_G	34_G	0.771	1.00
441_G	445_I	0.771	1.00
472_V	475_M	0.770	1.00
193_N	343_S	0.770	1.00
391_L	395_W	0.768	1.00
207_F	210_I	0.765	1.00
315_M	319_T	0.764	1.00
9_F	338_F	0.764	1.00
231_K	238_P	0.761	1.00
223_Q	227_V	0.760	1.00
254_V	257_F	0.758	1.00
85_T	89_L	0.757	1.00
428_F	432_P	0.755	0.99
310_L	319_T	0.754	0.99
255_N	262_N	0.752	0.99
94_L	278_G	0.751	0.99
186_M	347_G	0.750	0.99
446_S	450_I	0.750	0.99
380_K	383_F	0.750	0.99
193_N	344_T	0.748	0.99
177_Y	185_A	0.748	0.99
95_P	279_Q	0.748	0.99
24_V	180_I	0.748	0.99
484_R	487_P	0.747	0.99
252_I	257_F	0.747	0.99
22_W	25_R	0.745	0.99
60_Q	293_P	0.745	0.99
483_P	486_T	0.744	0.99
69_Y	309_D	0.743	0.99
161_A	169_L	0.741	0.99
404_Y	408_K	0.741	0.99
403_L	407_M	0.741	0.99
485_A	488_F	0.740	0.99
391_L	394_P	0.740	0.99
402_G	405_S	0.739	0.99
20_T	24_V	0.738	0.99
193_N	342_I	0.736	0.99
382_G	386_A	0.735	0.99
198_V	202_L	0.727	0.99
61_L	333_F	0.726	0.99
486_T	490_F	0.724	0.99
119_I	123_F	0.723	0.99
8_S	331_G	0.723	0.99
22_W	188_V	0.722	0.99
163_I	167_V	0.719	0.99
69_Y	316_A	0.718	0.99
125_F	128_A	0.717	0.99
353_S	382_G	0.716	0.99
50_S	190_D	0.716	0.99
481_I	484_R	0.716	0.99
485_A	490_F	0.715	0.99
272_S	277_E	0.712	0.99
7_L	14_L	0.712	0.99
468_F	471_N	0.708	0.99
424_M	428_F	0.703	0.99
356_F	377_V	0.702	0.99
446_S	449_T	0.701	0.99
26_K	184_R	0.701	0.99
398_N	401_Q	0.700	0.99
143_L	146_N	0.696	0.99
328_P	332_F	0.696	0.99
20_T	23_K	0.695	0.99
27_T	184_R	0.692	0.99
299_P	317_Y	0.691	0.99
53_L	193_N	0.691	0.99
408_K	412_G	0.689	0.99
143_L	314_D	0.687	0.99
57_S	61_L	0.686	0.99
444_I	448_I	0.684	0.99
183_L	187_A	0.683	0.99
54_T	263_Q	0.683	0.99
86_L	89_L	0.683	0.99
35_Y	382_G	0.681	0.99
107_D	111_E	0.680	0.99
390_V	394_P	0.679	0.99
188_V	191_S	0.679	0.99
212_M	305_H	0.678	0.99
234_S	238_P	0.677	0.99
137_V	345_F	0.676	0.99
109_L	421_I	0.676	0.99
114_D	117_T	0.676	0.99
220_G	305_H	0.676	0.99
16_V	20_T	0.673	0.99
361_Y	367_Q	0.671	0.99
27_T	375_V	0.671	0.99
357_S	374_L	0.669	0.99
34_G	184_R	0.669	0.99
166_L	170_L	0.669	0.99
227_V	304_F	0.669	0.99
353_S	381_F	0.668	0.99
217_F	220_G	0.668	0.99
8_S	328_P	0.667	0.99
210_I	217_F	0.667	0.99
304_F	316_A	0.666	0.99
242_L	246_A	0.666	0.99
232_L	237_G	0.666	0.99
121_I	418_L	0.666	0.99
344_T	348_F	0.665	0.99
348_F	351_S	0.664	0.99
118_R	122_D	0.663	0.99
231_K	236_G	0.663	0.99
103_A	107_D	0.662	0.99
244_I	248_F	0.660	0.99
190_D	343_S	0.659	0.99
117_T	433_A	0.659	0.99
23_K	188_V	0.659	0.99
246_A	250_G	0.659	0.99
141_G	341_V	0.658	0.99
315_M	318_P	0.658	0.99
263_Q	351_S	0.657	0.99
448_I	452_Y	0.656	0.99
5_Q	331_G	0.656	0.99
42_L	47_I	0.653	0.99
462_Y	466_C	0.649	0.98
121_I	128_A	0.649	0.98
54_T	268_R	0.646	0.98
21_W	24_V	0.646	0.98
79_E	86_L	0.642	0.98
45_P	49_A	0.640	0.98
114_D	486_T	0.639	0.98
175_I	179_V	0.639	0.98
8_S	335_A	0.638	0.98
45_P	191_S	0.638	0.98
17_A	176_L	0.637	0.98
239_T	242_L	0.637	0.98
19_I	23_K	0.634	0.98
463_V	467_T	0.633	0.98
133_F	348_F	0.632	0.98
407_M	411_N	0.631	0.98
121_I	125_F	0.630	0.98
63_G	133_F	0.630	0.98
32_Q	371_P	0.629	0.98
388_V	391_L	0.628	0.98
95_P	275_L	0.628	0.98
42_L	271_A	0.627	0.98
467_T	471_N	0.626	0.98
167_V	171_G	0.626	0.98
204_V	333_F	0.626	0.98
33_Q	371_P	0.625	0.98
263_Q	354_T	0.623	0.98
12_F	193_N	0.623	0.98
142_A	163_I	0.622	0.98
431_I	439_A	0.621	0.98
146_N	162_A	0.621	0.98
478_I	481_I	0.620	0.98
366_N	371_P	0.620	0.98
96_R	99_K	0.618	0.98
430_R	434_L	0.618	0.98
349_L	382_G	0.617	0.98
186_M	268_R	0.614	0.98
137_V	344_T	0.614	0.98
175_I	383_F	0.613	0.98
320_L	324_V	0.612	0.98
138_L	185_A	0.610	0.98
53_L	194_G	0.609	0.98
178_A	346_N	0.608	0.98
401_Q	406_W	0.608	0.98
201_G	295_V	0.608	0.98
145_L	166_L	0.607	0.98
390_V	393_A	0.606	0.98
53_L	190_D	0.606	0.98
87_I	282_A	0.605	0.98
202_L	205_P	0.605	0.98
94_L	275_L	0.604	0.98
11_G	18_V	0.603	0.98
17_A	24_V	0.601	0.97
297_V	301_L	0.600	0.97
365_I	368_N	0.600	0.97
5_Q	8_S	0.599	0.97
434_L	437_K	0.596	0.97
224_L	227_V	0.596	0.97
419_V	423_I	0.595	0.97
93_F	97_Y	0.595	0.97
247_A	250_G	0.594	0.97
258_Y	262_N	0.593	0.97
139_Y	143_L	0.592	0.97
249_T	257_F	0.592	0.97
78_W	82_S	0.591	0.97
16_V	24_V	0.590	0.97
268_R	347_G	0.588	0.97
325_L	329_M	0.588	0.97
55_N	289_K	0.588	0.97
113_Y	424_M	0.588	0.97
461_L	465_A	0.587	0.97
228_H	237_G	0.586	0.97
443_G	446_S	0.586	0.97
117_T	121_I	0.585	0.97
208_G	213_G	0.584	0.97
147_S	315_M	0.583	0.97
204_V	321_V	0.583	0.97
348_F	418_L	0.583	0.97
16_V	23_K	0.583	0.97
482_K	485_A	0.581	0.97
26_K	30_G	0.580	0.97
193_N	340_A	0.580	0.97
79_E	82_S	0.579	0.97
307_Y	319_T	0.579	0.97
171_G	393_A	0.578	0.97
13_T	17_A	0.577	0.97
209_L	213_G	0.577	0.97
104_T	359_G	0.577	0.97
119_I	363_R	0.577	0.97
342_I	346_N	0.576	0.97
209_L	298_L	0.574	0.97
119_I	122_D	0.574	0.97
286_A	290_M	0.574	0.97
227_V	231_K	0.574	0.97
443_G	474_V	0.573	0.97
184_R	188_V	0.572	0.97
102_I	107_D	0.571	0.97
113_Y	436_A	0.570	0.97
114_D	488_F	0.570	0.97
49_A	288_L	0.570	0.97
32_Q	374_L	0.570	0.97
229_A	235_I	0.570	0.97
143_L	147_S	0.569	0.97
439_A	442_I	0.568	0.96
459_H	466_C	0.568	0.96
305_H	308_Q	0.566	0.96
67_Q	70_K	0.566	0.96
438_V	441_G	0.566	0.96
57_S	137_V	0.566	0.96
250_G	253_L	0.565	0.96
447_Y	467_T	0.565	0.96
408_K	411_N	0.563	0.96
243_P	246_A	0.563	0.96
54_T	178_A	0.561	0.96
43_K	46_V	0.560	0.96
251_L	254_V	0.558	0.96
465_A	469_C	0.557	0.96
326_P	329_M	0.555	0.96
205_P	298_L	0.554	0.96
43_K	47_I	0.554	0.96
161_A	165_L	0.554	0.96
289_K	293_P	0.554	0.96
306_L	320_L	0.554	0.96
186_M	350_N	0.554	0.96
304_F	308_Q	0.553	0.96
229_A	234_S	0.553	0.96
189_A	268_R	0.553	0.96
96_R	427_F	0.553	0.96
52_M	292_D	0.551	0.96
12_F	336_V	0.551	0.96
142_A	166_L	0.550	0.96
134_L	345_F	0.550	0.96
67_Q	75_V	0.549	0.96
374_L	378_G	0.549	0.96
446_S	467_T	0.549	0.96
55_N	82_S	0.548	0.96
436_A	443_G	0.548	0.96
145_L	149_F	0.547	0.96
435_A	474_V	0.547	0.96
125_F	418_L	0.547	0.96
445_I	448_I	0.546	0.96
31_S	39_G	0.545	0.96
473_V	476_L	0.545	0.96
106_P	121_I	0.544	0.96
59_E	411_N	0.544	0.96
438_V	477_V	0.544	0.96
263_Q	348_F	0.543	0.95
353_S	378_G	0.542	0.95
129_T	348_F	0.540	0.95
57_S	260_C	0.539	0.95
115_K	118_R	0.538	0.95
430_R	433_A	0.538	0.95
314_D	425_G	0.538	0.95
301_L	305_H	0.538	0.95
122_D	355_L	0.537	0.95
199_I	202_L	0.537	0.95
52_M	194_G	0.536	0.95
32_Q	35_Y	0.536	0.95
327_V	330_V	0.535	0.95
280_K	284_L	0.535	0.95
106_P	125_F	0.535	0.95
431_I	436_A	0.535	0.95
177_Y	181_G	0.534	0.95
451_N	463_V	0.534	0.95
362_R	371_P	0.534	0.95
228_H	236_G	0.534	0.95
230_E	236_G	0.533	0.95
32_Q	36_F	0.533	0.95
325_L	333_F	0.532	0.95
86_L	289_K	0.529	0.95
64_L	68_A	0.529	0.95
361_Y	374_L	0.528	0.95
35_Y	379_R	0.528	0.95
51_L	348_F	0.528	0.95
210_I	213_G	0.527	0.95
46_V	188_V	0.527	0.95
122_D	360_I	0.527	0.95
217_F	225_T	0.527	0.95
230_E	234_S	0.526	0.95
357_S	381_F	0.526	0.95
55_N	411_N	0.526	0.95
81_T	90_A	0.526	0.95
133_F	137_V	0.524	0.95
131_V	388_V	0.523	0.94
430_R	476_L	0.523	0.94
203_M	206_V	0.523	0.94
168_I	387_I	0.523	0.94
4_L	327_V	0.523	0.94
24_V	27_T	0.522	0.94
40_R	98_L	0.521	0.94
253_L	256_T	0.521	0.94
340_A	343_S	0.521	0.94
105_I	422_I	0.521	0.94
306_L	324_V	0.521	0.94
187_A	190_D	0.521	0.94
219_Q	305_H	0.520	0.94
16_V	21_W	0.519	0.94
420_T	475_M	0.518	0.94
48_A	52_M	0.518	0.94
13_T	20_T	0.517	0.94
254_V	259_W	0.517	0.94
280_K	283_L	0.515	0.94
245_G	249_T	0.513	0.94
442_I	445_I	0.513	0.94
147_S	318_P	0.513	0.94
230_E	235_I	0.512	0.94
128_A	413_I	0.512	0.94
114_D	489_T	0.511	0.94
249_T	465_A	0.511	0.94
59_E	133_F	0.510	0.94
412_G	447_Y	0.510	0.94
458_F	461_L	0.508	0.94
89_L	94_L	0.507	0.94
85_T	88_F	0.505	0.93
136_I	410_L	0.505	0.93
460_F	464_L	0.504	0.93
330_V	334_G	0.504	0.93
128_A	414_Y	0.502	0.93
440_M	443_G	0.502	0.93
4_L	328_P	0.502	0.93
275_L	279_Q	0.502	0.93
137_V	140_S	0.501	0.93
43_K	188_V	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2xq2A	2	0.9002	100	0.223	Contact Map
3dh4A	3	0.8214	100	0.28	Contact Map
3l1lA	2	0.718	99.3	0.876	Contact Map
3giaA	1	0.7373	99.1	0.882	Contact Map
4wgvA	2	0.6427	99.1	0.887	Contact Map
2jlnA	1	0.7373	98.7	0.901	Contact Map
4djkA	2	0.718	98.6	0.903	Contact Map
4c7rA	3	0.7706	96.5	0.937	Contact Map
2a65A	2	0.7688	94.9	0.944	Contact Map
2wswA	3	0.7023	94.8	0.944	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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