GREMLIN Database
ADEC - Adenine deaminase
UniProt: P31441 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11692
Length: 588 (558)
Sequences: 1535 (1133)
Seq/√Len: 48.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
34_I77_A4.9391.00
494_Q513_H4.2821.00
494_Q497_Q4.1351.00
52_I82_A4.0261.00
480_V488_M3.7221.00
409_R582_T3.5621.00
167_T170_Q3.4651.00
525_D529_S3.4211.00
484_S487_E3.3721.00
86_F352_V3.2911.00
39_I50_G3.2901.00
439_F485_A3.2731.00
110_R298_D3.2611.00
409_R422_S3.2441.00
77_A345_L3.1641.00
298_D302_R3.1421.00
46_G248_Q3.1091.00
358_L363_P3.1001.00
347_S353_T3.0751.00
22_A27_D3.0721.00
464_E506_R3.0651.00
102_T105_T2.9941.00
37_V82_A2.9131.00
186_M199_L2.8881.00
440_I568_L2.8501.00
395_A486_E2.7491.00
565_A577_E2.7391.00
478_I492_V2.6901.00
23_V60_A2.6421.00
412_D458_G2.6271.00
277_P325_R2.6231.00
441_A488_M2.6051.00
525_D533_Q2.5981.00
468_A491_A2.5241.00
38_S49_S2.5061.00
441_A480_V2.4861.00
83_V346_L2.4631.00
498_D513_H2.4611.00
82_A343_I2.4451.00
161_V570_S2.4321.00
82_A345_L2.4001.00
37_V77_A2.3591.00
33_I71_A2.3401.00
412_D423_H2.3151.00
487_E508_G2.3031.00
457_L558_L2.2911.00
347_S355_Q2.2651.00
132_A177_H2.2601.00
188_D191_G2.2571.00
421_H565_A2.2241.00
41_D44_N2.2091.00
139_E179_Q2.1991.00
34_I345_L2.1801.00
281_L304_L2.1711.00
398_F492_V2.1451.00
293_H535_D2.0871.00
305_I352_V2.0701.00
412_D421_H2.0581.00
40_L83_V2.0391.00
504_V540_A2.0241.00
348_D351_K1.9980.99
136_R139_E1.9940.99
80_A355_Q1.9720.99
43_I334_L1.9600.99
575_D578_K1.9600.99
493_N496_I1.9110.99
490_L494_Q1.8990.99
480_V492_V1.8890.99
38_S47_E1.8830.99
301_I344_V1.8830.99
22_A28_A1.8760.99
460_F481_I1.8720.99
395_A489_A1.8630.99
40_L47_E1.8550.99
356_Q363_P1.8380.99
470_T478_I1.8160.99
335_L343_I1.8130.99
39_I52_I1.7790.99
316_Y352_V1.7710.99
512_S540_A1.7680.99
489_A493_N1.7670.99
365_D368_T1.7470.99
123_V131_F1.7400.98
80_A345_L1.7360.98
224_N249_L1.7350.98
400_L456_L1.7070.98
265_N307_Q1.7070.98
75_I358_L1.7030.98
161_V571_Q1.6780.98
149_V171_M1.6730.98
265_N303_R1.6720.98
132_A136_R1.6590.98
495_V503_C1.6440.98
247_L279_C1.6370.98
444_E450_L1.6200.98
144_N332_L1.6200.98
93_I145_Q1.6160.98
490_L508_G1.6100.97
59_I343_I1.6100.97
41_D46_G1.6040.97
112_L296_H1.6010.97
98_M530_L1.5940.97
23_V55_K1.5880.97
41_D48_I1.5870.97
345_L358_L1.5840.97
25_R222_E1.5810.97
45_G314_V1.5800.97
36_N76_D1.5790.97
31_D55_K1.5780.97
498_D503_C1.5670.97
316_Y320_S1.5640.97
126_M519_A1.5630.97
281_L297_I1.5610.97
390_R496_I1.5450.97
356_Q366_A1.5420.97
443_L492_V1.5390.97
494_Q498_D1.5340.97
159_C574_F1.5240.96
19_E55_K1.5230.96
422_S582_T1.5100.96
393_V489_A1.5080.96
340_Q360_K1.4770.96
32_Y54_I1.4610.95
408_Y456_L1.4520.95
252_S280_M1.4470.95
505_V510_V1.4440.95
45_G317_R1.4420.95
303_R307_Q1.4420.95
388_I470_T1.4400.95
60_A228_T1.4400.95
517_P524_T1.4370.95
109_P365_D1.4360.95
407_R425_S1.4360.95
203_L211_L1.4330.95
29_V72_L1.4250.95
80_A347_S1.4180.95
89_A282_C1.4150.95
437_V456_L1.4140.95
408_Y426_V1.4110.95
144_N360_K1.4070.94
400_L454_C1.4060.94
106_A527_A1.4000.94
29_V70_P1.3900.94
441_A454_C1.3850.94
129_A132_A1.3720.94
40_L316_Y1.3660.94
233_N326_H1.3640.93
398_F489_A1.3620.93
144_N359_V1.3510.93
19_E56_G1.3480.93
244_R248_Q1.3410.93
561_P569_T1.3380.93
495_V498_D1.3350.93
317_R321_W1.3290.93
426_V456_L1.3250.92
309_N318_V1.3210.92
438_S483_R1.3200.92
132_A173_A1.3180.92
257_E265_N1.3140.92
261_A418_L1.3070.92
30_A53_V1.3030.92
464_E483_R1.2970.92
40_L312_L1.2950.92
34_I54_I1.2910.91
148_Q182_G1.2900.91
52_I335_L1.2880.91
129_A383_P1.2790.91
172_L207_R1.2730.91
252_S278_Q1.2670.91
470_T492_V1.2640.91
539_A543_E1.2600.90
271_I318_V1.2580.90
301_I319_A1.2480.90
574_F581_F1.2470.90
254_M282_C1.2420.90
515_P533_Q1.2390.90
263_N266_A1.2390.90
566_L582_T1.2350.89
303_R306_E1.2340.89
301_I305_I1.2310.89
518_I524_T1.2250.89
43_I339_K1.2250.89
132_A174_W1.2210.89
443_L470_T1.2180.89
529_S532_E1.2150.89
45_G312_L1.2150.89
263_N417_E1.2120.89
236_E256_R1.2060.88
54_I343_I1.2050.88
161_V451_A1.2010.88
138_A179_Q1.1940.88
504_V544_C1.1940.88
282_C327_F1.1940.88
188_D196_Q1.1910.88
393_V398_F1.1830.87
523_S530_L1.1810.87
468_A480_V1.1790.87
186_M191_G1.1780.87
346_L352_V1.1740.87
346_L354_V1.1740.87
135_A179_Q1.1690.87
227_I251_M1.1680.87
139_E177_H1.1670.87
388_I499_G1.1600.86
503_C513_H1.1600.86
487_E490_L1.1580.86
102_T527_A1.1560.86
433_D438_S1.1550.86
128_E174_W1.1520.86
40_L81_T1.1510.86
443_L452_P1.1500.86
19_E28_A1.1440.86
53_V63_G1.1370.85
277_P317_R1.1360.85
472_S479_V1.1350.85
23_V30_A1.1300.85
278_Q325_R1.1250.85
223_L245_R1.1240.85
240_L270_L1.1230.84
451_A570_S1.1210.84
195_G200_L1.1180.84
473_H476_H1.1170.84
297_I319_A1.1130.84
482_G488_M1.1110.84
22_A195_G1.1090.84
494_Q503_C1.1070.84
252_S326_H1.1060.84
138_A141_A1.1040.83
301_I320_S1.1040.83
148_Q181_T1.1020.83
252_S325_R1.1000.83
526_T529_S1.0970.83
479_V559_S1.0950.83
37_V345_L1.0940.83
107_T115_V1.0880.83
86_F344_V1.0860.82
495_V499_G1.0840.82
22_A25_R1.0840.82
201_D205_A1.0830.82
117_C147_L1.0830.82
387_T390_R1.0820.82
83_V344_V1.0760.82
305_I311_P1.0720.82
409_R424_S1.0700.81
444_E449_R1.0690.81
39_I62_V1.0680.81
99_T518_I1.0660.81
115_V143_Q1.0630.81
159_C581_F1.0600.81
334_L339_K1.0580.81
233_N327_F1.0530.80
71_A74_R1.0500.80
512_S536_A1.0500.80
48_I248_Q1.0470.80
332_L340_Q1.0460.80
343_I358_L1.0410.80
190_P579_F1.0400.80
491_A505_V1.0390.79
47_E349_A1.0380.79
398_F488_M1.0380.79
54_I358_L1.0370.79
317_R322_S1.0370.79
175_R209_L1.0360.79
280_M326_H1.0330.79
36_N78_R1.0330.79
407_R424_S1.0310.79
82_A335_L1.0280.79
282_C319_A1.0250.79
26_G221_K1.0250.79
37_V343_I1.0200.78
481_I555_M1.0190.78
396_S399_A1.0170.78
149_V174_W1.0120.78
33_I53_V1.0090.77
109_P143_Q1.0080.77
440_I481_I1.0070.77
160_D570_S1.0070.77
32_Y75_I1.0070.77
91_L103_F1.0040.77
311_P315_A1.0020.77
386_N499_G1.0010.77
44_N248_Q0.9930.76
479_V568_L0.9930.76
34_I358_L0.9930.76
35_D74_R0.9900.76
114_T146_Y0.9900.76
144_N340_Q0.9880.76
155_A475_S0.9870.76
402_F428_S0.9850.76
47_E81_T0.9840.76
254_M327_F0.9830.76
309_N315_A0.9690.75
331_H340_Q0.9690.75
440_I558_L0.9680.74
363_P366_A0.9680.74
42_L334_L0.9650.74
89_A323_T0.9640.74
469_A556_A0.9610.74
128_E173_A0.9590.74
440_I455_G0.9580.74
104_E142_R0.9570.74
50_G62_V0.9540.73
122_I130_G0.9450.73
146_Y181_T0.9410.72
268_A309_N0.9390.72
532_E536_A0.9380.72
73_Q362_E0.9380.72
220_G245_R0.9360.72
490_L510_V0.9320.72
191_G199_L0.9320.72
398_F441_A0.9310.72
59_I62_V0.9310.72
91_L283_T0.9270.71
240_L244_R0.9210.71
253_L270_L0.9200.71
23_V28_A0.9190.71
85_G113_T0.9180.70
108_L143_Q0.9170.70
574_F579_F0.9170.70
255_I281_L0.9160.70
32_Y358_L0.9150.70
188_D199_L0.9120.70
233_N282_C0.9110.70
414_I421_H0.9110.70
457_L460_F0.9100.70
276_S314_V0.9100.70
391_Q448_Q0.9050.69
533_Q536_A0.9050.69
24_S225_A0.9030.69
405_G425_S0.9010.69
81_T349_A0.9010.69
198_A202_K0.9000.69
355_Q367_Q0.8990.69
141_A145_Q0.8990.69
35_D51_P0.8990.69
187_M562_V0.8960.69
192_V203_L0.8960.69
254_M280_M0.8940.68
96_S103_F0.8940.68
441_A492_V0.8930.68
122_I134_F0.8900.68
464_E507_N0.8880.68
210_T326_H0.8880.68
120_H473_H0.8840.68
242_E245_R0.8840.68
301_I316_Y0.8840.68
219_G245_R0.8840.68
121_E473_H0.8830.67
468_A492_V0.8820.67
175_R205_A0.8820.67
152_C187_M0.8790.67
138_A145_Q0.8730.67
490_L505_V0.8720.66
243_G270_L0.8700.66
120_H187_M0.8700.66
297_I300_L0.8700.66
305_I316_Y0.8690.66
115_V145_Q0.8670.66
95_S473_H0.8670.66
103_F115_V0.8660.66
131_F174_W0.8650.66
120_H476_H0.8650.66
101_V137_C0.8630.66
392_P496_I0.8610.65
202_K206_F0.8580.65
249_L337_P0.8570.65
21_L195_G0.8560.65
199_L202_K0.8500.64
443_L478_I0.8500.64
112_L553_I0.8490.64
265_N306_E0.8490.64
506_R511_Q0.8460.64
95_S476_H0.8420.64
321_W325_R0.8410.64
467_L541_A0.8400.64
52_I62_V0.8400.64
457_L481_I0.8390.63
438_S481_I0.8390.63
381_A387_T0.8380.63
133_W137_C0.8380.63
152_C191_G0.8370.63
216_P246_K0.8370.63
89_A327_F0.8370.63
171_M175_R0.8360.63
126_M130_G0.8340.63
366_A369_L0.8320.63
95_S285_D0.8300.63
568_L573_L0.8280.62
175_R259_S0.8270.62
41_D334_L0.8260.62
436_D461_G0.8250.62
172_L205_A0.8250.62
175_R206_F0.8250.62
40_L349_A0.8240.62
391_Q496_I0.8230.62
53_V61_G0.8220.62
126_M384_Y0.8220.62
121_E476_H0.8210.62
166_F171_M0.8210.62
305_I348_D0.8190.62
517_P523_S0.8180.61
75_I363_P0.8170.61
348_D353_T0.8170.61
33_I74_R0.8160.61
131_F149_V0.8160.61
540_A543_E0.8130.61
200_L203_L0.8110.61
95_S120_H0.8090.61
73_Q363_P0.8080.61
77_A82_A0.8070.60
541_A544_C0.8030.60
494_Q510_V0.8020.60
243_G253_L0.7990.60
473_H560_L0.7910.59
281_L300_L0.7910.59
91_L96_S0.7900.59
545_G551_P0.7890.59
146_Y332_L0.7810.58
134_F522_M0.7810.58
255_I268_A0.7800.58
38_S81_T0.7780.58
116_I327_F0.7780.58
468_A495_V0.7780.58
149_V180_V0.7770.57
471_V521_L0.7760.57
362_E369_L0.7730.57
296_H553_I0.7710.57
514_L530_L0.7700.57
87_I116_I0.7700.57
219_G255_I0.7690.57
465_G487_E0.7660.56
27_D245_R0.7650.56
220_G223_L0.7600.56
107_T143_Q0.7550.55
47_E312_L0.7550.55
135_A147_L0.7540.55
39_I343_I0.7530.55
269_P307_Q0.7530.55
277_P322_S0.7530.55
103_F107_T0.7510.55
31_D72_L0.7510.55
541_A550_E0.7500.55
246_K253_L0.7500.55
423_H458_G0.7490.55
103_F296_H0.7450.54
418_L567_K0.7440.54
410_V423_H0.7430.54
354_V357_V0.7430.54
110_R354_V0.7430.54
329_L332_L0.7430.54
33_I51_P0.7390.54
104_E141_A0.7390.54
170_Q173_A0.7390.54
294_E299_A0.7380.54
161_V449_R0.7370.54
215_C246_K0.7370.54
89_A254_M0.7370.54
261_A557_F0.7360.53
87_I324_A0.7350.53
257_E303_R0.7320.53
87_I323_T0.7300.53
124_N163_G0.7300.53
151_S473_H0.7290.53
529_S533_Q0.7280.53
162_N475_S0.7280.53
20_L60_A0.7250.52
475_S561_P0.7240.52
433_D483_R0.7230.52
66_Y69_A0.7220.52
169_E201_D0.7190.52
484_S488_M0.7180.52
93_I100_P0.7180.52
514_L533_Q0.7170.52
98_M527_A0.7160.51
207_R509_Q0.7120.51
454_C485_A0.7080.51
121_E560_L0.7080.51
33_I69_A0.7070.51
472_S559_S0.7050.50
85_G320_S0.7040.50
286_R300_L0.7040.50
123_V234_C0.7000.50
310_V314_V0.6990.50
280_M323_T0.6960.49
187_M473_H0.6960.49
95_S121_E0.6960.49
281_L319_A0.6950.49
187_M476_H0.6930.49
171_M205_A0.6930.49
467_L504_V0.6920.49
223_L227_I0.6910.49
476_H560_L0.6910.49
28_A55_K0.6880.49
436_D459_G0.6880.49
95_S560_L0.6860.48
238_Y419_I0.6860.48
151_S183_L0.6860.48
40_L346_L0.6860.48
393_V492_V0.6850.48
95_S187_M0.6840.48
59_I335_L0.6820.48
227_I249_L0.6810.48
305_I347_S0.6800.48
42_L317_R0.6800.48
243_G320_S0.6790.48
173_A176_D0.6790.48
160_D561_P0.6780.48
176_D207_R0.6760.47
114_T144_N0.6750.47
392_P497_Q0.6740.47
314_V317_R0.6730.47
336_A339_K0.6720.47
511_Q544_C0.6720.47
285_D473_H0.6720.47
121_E125_V0.6700.47
330_N339_K0.6690.47
241_E245_R0.6660.46
460_F469_A0.6650.46
42_L312_L0.6650.46
507_N510_V0.6650.46
283_T504_V0.6650.46
240_L243_G0.6630.46
470_T498_D0.6630.46
285_D476_H0.6620.46
151_S187_M0.6610.46
124_N476_H0.6600.46
426_V437_V0.6590.46
471_V502_L0.6590.46
288_P553_I0.6580.46
487_E507_N0.6580.46
316_Y346_L0.6570.46
120_H154_P0.6550.45
120_H560_L0.6540.45
259_S327_F0.6540.45
241_E425_S0.6530.45
253_L279_C0.6530.45
488_M492_V0.6510.45
86_F320_S0.6510.45
455_G568_L0.6490.45
193_I225_A0.6490.45
153_V560_L0.6480.45
91_L296_H0.6480.45
438_S457_L0.6450.44
151_S476_H0.6440.44
523_S533_Q0.6420.44
247_L253_L0.6410.44
345_L355_Q0.6390.44
75_I356_Q0.6370.44
237_S242_E0.6370.44
316_Y349_A0.6370.44
96_S107_T0.6370.44
85_G342_D0.6360.43
121_E474_D0.6350.43
73_Q396_S0.6340.43
200_L206_F0.6340.43
552_F556_A0.6330.43
156_L475_S0.6310.43
211_L231_I0.6290.43
117_C184_A0.6280.43
571_Q581_F0.6270.43
74_R78_R0.6260.42
20_L23_V0.6250.42
128_E170_Q0.6250.42
197_N201_D0.6250.42
536_A540_A0.6250.42
436_D483_R0.6240.42
123_V166_F0.6240.42
124_N473_H0.6230.42
97_M471_V0.6230.42
54_I301_I0.6210.42
541_A546_P0.6210.42
73_Q366_A0.6210.42
236_E258_G0.6200.42
123_V174_W0.6200.42
286_R297_I0.6200.42
398_F480_V0.6180.42
97_M287_N0.6170.42
418_L563_I0.6170.42
386_N389_A0.6160.41
428_S431_G0.6160.41
112_L470_T0.6150.41
317_R320_S0.6150.41
125_V163_G0.6150.41
289_W550_E0.6140.41
25_R225_A0.6140.41
89_A472_S0.6130.41
94_E285_D0.6130.41
311_P316_Y0.6120.41
117_C203_L0.6120.41
320_S324_A0.6120.41
282_C297_I0.6120.41
344_V354_V0.6110.41
135_A177_H0.6100.41
153_V187_M0.6090.41
55_K60_A0.6080.41
125_V446_Y0.6080.41
414_I417_E0.6080.41
217_G419_I0.6080.41
384_Y387_T0.6070.41
365_D370_Q0.6070.41
408_Y455_G0.6070.41
239_Q242_E0.6070.41
422_S566_L0.6060.40
86_F346_L0.6060.40
453_A568_L0.6050.40
385_G524_T0.6050.40
390_R443_L0.6050.40
188_D456_L0.6050.40
34_I343_I0.6040.40
181_T192_V0.6040.40
420_T562_V0.6030.40
23_V228_T0.6030.40
97_M516_L0.6020.40
95_S151_S0.6020.40
418_L557_F0.5990.40
348_D358_L0.5990.40
223_L249_L0.5980.40
394_S397_D0.5970.40
153_V476_H0.5970.40
242_E442_V0.5970.40
283_T300_L0.5970.40
273_E523_S0.5970.40
486_E490_L0.5960.40
381_A388_I0.5960.40
113_T283_T0.5960.40
504_V552_F0.5950.39
305_I321_W0.5940.39
104_E523_S0.5940.39
34_I82_A0.5940.39
155_A187_M0.5930.39
517_P525_D0.5930.39
124_N154_P0.5920.39
254_M326_H0.5920.39
88_D296_H0.5920.39
245_R249_L0.5920.39
233_N254_M0.5920.39
86_F354_V0.5910.39
446_Y450_L0.5910.39
247_L309_N0.5910.39
215_C218_L0.5900.39
497_Q513_H0.5900.39
389_A447_G0.5900.39
442_V570_S0.5890.39
272_N275_N0.5880.39
104_E138_A0.5870.39
306_E434_R0.5850.38
215_C242_E0.5850.38
299_A302_R0.5840.38
41_D339_K0.5830.38
121_E285_D0.5820.38
120_H152_C0.5810.38
124_N560_L0.5810.38
98_M288_P0.5790.38
73_Q356_Q0.5780.38
459_G569_T0.5770.38
120_H153_V0.5770.38
409_R566_L0.5770.38
20_L56_G0.5770.38
247_L270_L0.5760.38
108_L365_D0.5760.38
122_I519_A0.5760.38
291_I296_H0.5750.38
276_S318_V0.5750.38
183_L206_F0.5720.37
41_D249_L0.5700.37
255_I303_R0.5690.37
538_K550_E0.5690.37
436_D458_G0.5680.37
162_N171_M0.5680.37
120_H562_V0.5670.37
381_A384_Y0.5670.37
305_I354_V0.5670.37
320_S323_T0.5660.37
285_D477_N0.5650.37
87_I114_T0.5650.37
486_E508_G0.5640.37
171_M203_L0.5630.36
306_E351_K0.5630.36
265_N301_I0.5630.36
302_R354_V0.5620.36
152_C475_S0.5610.36
369_L396_S0.5610.36
212_D233_N0.5610.36
523_S526_T0.5600.36
285_D474_D0.5590.36
54_I345_L0.5590.36
27_D195_G0.5580.36
410_V536_A0.5580.36
120_H151_S0.5560.36
96_S477_N0.5560.36
337_P566_L0.5560.36
149_V175_R0.5560.36
393_V443_L0.5560.36
432_F483_R0.5560.36
432_F535_D0.5560.36
103_F567_K0.5560.36
130_G134_F0.5560.36
504_V537_L0.5560.36
542_R580_A0.5550.36
405_G434_R0.5550.36
470_T491_A0.5540.36
120_H124_N0.5540.36
237_S263_N0.5520.35
202_K242_E0.5520.35
39_I47_E0.5520.35
258_G439_F0.5520.35
269_P272_N0.5520.35
279_C318_V0.5510.35
130_G519_A0.5510.35
58_Y330_N0.5510.35
83_V316_Y0.5510.35
390_R493_N0.5500.35
152_C155_A0.5500.35
233_N574_F0.5490.35
438_S546_P0.5480.35
260_A280_M0.5480.35
165_S495_V0.5460.35
174_W177_H0.5460.35
97_M418_L0.5440.35
241_E507_N0.5440.35
94_E120_H0.5430.35
240_L269_P0.5420.34
462_L544_C0.5420.34
224_N337_P0.5420.34
301_I352_V0.5410.34
144_N342_D0.5400.34
107_T152_C0.5400.34
108_L359_V0.5390.34
305_I350_R0.5380.34
289_W343_I0.5380.34
402_F409_R0.5380.34
248_Q507_N0.5370.34
416_N549_D0.5360.34
124_N187_M0.5350.34
69_A72_L0.5350.34
511_Q540_A0.5350.34
410_V437_V0.5350.34
137_C140_Q0.5340.34
76_D79_G0.5340.34
83_V335_L0.5330.34
124_N285_D0.5330.34
53_V71_A0.5330.34
116_I580_A0.5320.34
96_S233_N0.5320.34
38_S78_R0.5320.34
120_H474_D0.5320.34
257_E262_R0.5310.33
129_A197_N0.5310.33
52_I360_K0.5310.33
346_L355_Q0.5300.33
489_A496_I0.5300.33
133_W136_R0.5300.33
86_F309_N0.5300.33
142_R568_L0.5300.33
551_P557_F0.5300.33
484_S507_N0.5290.33
115_V504_V0.5290.33
169_E539_A0.5290.33
61_G224_N0.5280.33
266_A269_P0.5280.33
120_H125_V0.5280.33
154_P473_H0.5270.33
121_E187_M0.5270.33
209_L518_I0.5270.33
272_N309_N0.5260.33
565_A575_D0.5260.33
180_V209_L0.5260.33
187_M191_G0.5250.33
96_S285_D0.5250.33
49_S78_R0.5250.33
558_L567_K0.5250.33
124_N153_V0.5240.33
187_M560_L0.5240.33
204_D539_A0.5240.33
255_I265_N0.5240.33
244_R270_L0.5240.33
148_Q212_D0.5240.33
120_H285_D0.5230.33
509_Q532_E0.5230.33
430_N578_K0.5230.33
363_P403_T0.5230.33
137_C225_A0.5230.33
186_M231_I0.5220.33
70_P74_R0.5220.33
437_V455_G0.5220.33
114_T325_R0.5220.33
217_G247_L0.5210.33
121_E151_S0.5200.33
27_D193_I0.5200.33
54_I239_Q0.5200.33
525_D530_L0.5200.33
125_V153_V0.5190.32
83_V86_F0.5190.32
156_L561_P0.5180.32
51_P65_E0.5180.32
32_Y57_R0.5180.32
205_A455_G0.5180.32
402_F426_V0.5170.32
210_T323_T0.5170.32
345_L362_E0.5160.32
89_A280_M0.5150.32
80_A346_L0.5140.32
70_P73_Q0.5130.32
112_L216_P0.5130.32
446_Y560_L0.5130.32
95_S562_V0.5130.32
286_R299_A0.5120.32
534_I538_K0.5110.32
459_G472_S0.5100.32
233_N253_L0.5100.32
155_A568_L0.5100.32
105_T141_A0.5090.32
455_G514_L0.5080.31
356_Q367_Q0.5080.31
370_Q374_S0.5080.31
298_D354_V0.5080.31
428_S432_F0.5070.31
366_A373_E0.5060.31
51_P71_A0.5060.31
281_L318_V0.5050.31
400_L426_V0.5050.31
261_A287_N0.5050.31
217_G239_Q0.5050.31
311_P349_A0.5030.31
128_E132_A0.5030.31
289_W535_D0.5030.31
216_P553_I0.5020.31
191_G456_L0.5020.31
312_L316_Y0.5020.31
153_V473_H0.5020.31
387_T576_G0.5010.31
121_E124_N0.5010.31
224_N298_D0.5000.31
446_Y449_R0.5000.31
83_V352_V0.5000.31
392_P543_E0.5000.31
152_C562_V0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3nqbA 2 0.9779 100 0.322 Contact Map
2icsA 1 0.551 100 0.801 Contact Map
2vunA 3 0.5714 100 0.802 Contact Map
2ogjA 4 0.568 100 0.806 Contact Map
3mtwA 5 0.5561 100 0.811 Contact Map
3be7A 5 0.5561 100 0.811 Contact Map
4whbE 3 0.5816 100 0.813 Contact Map
1onwA 5 0.5748 100 0.815 Contact Map
3lnpA 2 0.5901 100 0.816 Contact Map
4c65A 6 0.5765 100 0.819 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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