GREMLIN Database
XYLS - Alpha-xylosidase
UniProt: P31434 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11685
Length: 772 (669)
Sequences: 3962 (2644)
Seq/√Len: 102.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
292_G296_R4.8481.00
327_D330_G4.7901.00
336_K411_D4.3421.00
298_L563_T4.1281.00
255_T260_R3.9731.00
292_G295_E3.8151.00
287_N334_R3.6731.00
291_D295_E3.6291.00
707_D710_V3.6061.00
209_L470_V3.5501.00
333_R337_A3.5371.00
522_H623_A3.5271.00
363_K393_D3.1771.00
256_R260_R3.1091.00
598_D629_Y3.1051.00
595_F609_M3.0841.00
573_L610_L3.0651.00
329_E333_R3.0501.00
627_Q651_K3.0311.00
459_E709_S3.0141.00
359_E401_K2.9991.00
591_M607_Q2.9771.00
446_E450_N2.9561.00
297_N564_Q2.9301.00
606_R626_V2.9291.00
613_N667_T2.8491.00
512_I531_G2.7261.00
111_R123_L2.6611.00
364_G368_K2.6171.00
246_T249_A2.5871.00
637_H640_H2.5531.00
360_L366_L2.5461.00
634_R643_E2.5301.00
162_V200_Y2.4811.00
96_N114_K2.4811.00
520_P622_E2.4781.00
296_R556_C2.4711.00
249_A252_D2.4651.00
578_A582_A2.4621.00
617_A628_F2.4571.00
358_K362_E2.4461.00
652_Q662_Y2.4341.00
297_N560_R2.4181.00
365_Y394_A2.3831.00
300_L340_L2.3651.00
607_Q615_M2.3501.00
66_G238_E2.3371.00
293_M548_P2.3071.00
464_F477_V2.2831.00
290_I300_L2.2531.00
634_R645_D2.2481.00
625_D651_K2.2451.00
248_K594_E2.2281.00
558_V562_F2.2071.00
329_E408_M2.2051.00
291_D338_K2.2031.00
655_G658_S2.1871.00
491_A621_T2.1861.00
161_T173_V2.1301.00
369_R373_S2.1111.00
265_P268_S2.0981.00
670_A688_F2.0961.00
242_I253_R2.0721.00
199_F207_G2.0661.00
211_N238_E2.0581.00
211_N240_F2.0491.00
630_L650_H2.0481.00
627_Q649_W2.0441.00
630_L662_Y2.0411.00
392_P428_F2.0381.00
396_K400_D2.0281.00
579_R583_R2.0151.00
65_V110_A2.0131.00
528_C559_V2.0111.00
109_S123_L1.9991.00
637_H658_S1.9791.00
247_P596_P1.9421.00
357_F385_A1.9391.00
307_C345_W1.8901.00
634_R665_D1.8781.00
560_R564_Q1.8781.00
561_F657_L1.8761.00
393_D396_K1.8541.00
625_D653_Q1.8441.00
617_A626_V1.8431.00
399_A454_D1.8431.00
589_R594_E1.8411.00
269_F577_A1.8311.00
330_G334_R1.8221.00
353_K358_K1.8201.00
468_A472_A1.8191.00
110_A120_L1.8121.00
617_A662_Y1.8121.00
391_N394_A1.8001.00
320_W328_P1.7941.00
501_G590_A1.7831.00
553_D557_D1.7691.00
512_I537_S1.7561.00
601_C629_Y1.7321.00
252_D583_R1.7321.00
254_Y470_V1.7271.00
387_Y394_A1.7271.00
525_K555_S1.7261.00
600_A649_W1.7211.00
403_K407_A1.7211.00
663_V691_F1.7141.00
616_V661_V1.7061.00
579_R612_D1.6951.00
361_Q374_L1.6911.00
638_L671_L1.6821.00
67_V239_Y1.6771.00
644_L662_Y1.6751.00
305_F342_I1.6591.00
403_K454_D1.6581.00
614_V669_L1.6241.00
111_R121_D1.6211.00
281_Y331_M1.6211.00
309_W405_L1.6191.00
638_L661_V1.6121.00
609_M635_W1.6071.00
723_I727_G1.6041.00
557_D560_R1.5951.00
530_F608_Y1.5911.00
510_H534_S1.5811.00
100_Y111_R1.5771.00
124_R128_R1.5761.00
700_V724_T1.5751.00
63_G253_R1.5721.00
534_S608_Y1.5701.00
614_V663_V1.5691.00
291_D334_R1.5671.00
562_F659_L1.5631.00
630_L652_Q1.5601.00
281_Y287_N1.5591.00
311_K314_Q1.5431.00
107_N125_N1.5391.00
713_T716_A1.5381.00
290_I340_L1.5361.00
621_T624_G1.5221.00
207_G250_V1.5151.00
286_V305_F1.5131.00
601_C604_L1.5101.00
183_N196_N1.5041.00
247_P592_M1.5031.00
497_G508_W1.4971.00
210_V232_V1.4941.00
638_L663_V1.4931.00
446_E475_F1.4881.00
577_A587_M1.4871.00
162_V202_T1.4791.00
619_V626_V1.4741.00
178_T219_E1.4721.00
60_P64_I1.4691.00
201_M247_P1.4601.00
585_T593_M1.4571.00
700_V722_T1.4501.00
525_K656_F1.4411.00
668_L690_L1.4401.00
293_M300_L1.4311.00
443_I446_E1.4191.00
450_N453_K1.4141.00
494_L620_F1.4121.00
671_L689_H1.4091.00
113_S116_E1.4081.00
281_Y327_D1.4031.00
290_I335_L1.4011.00
297_N676_Q1.3951.00
591_M609_M1.3901.00
216_V232_V1.3891.00
244_G249_A1.3771.00
67_V122_F1.3720.99
613_N664_R1.3670.99
104_K109_S1.3640.99
272_W304_H1.3590.99
628_F652_Q1.3590.99
399_A451_V1.3570.99
554_E557_D1.3520.99
154_L228_V1.3510.99
321_D324_T1.3490.99
359_E363_K1.3480.99
264_P269_F1.3460.99
252_D585_T1.3460.99
271_L293_M1.3370.99
358_K361_Q1.3370.99
65_V122_F1.3350.99
127_E130_T1.3310.99
391_N428_F1.3300.99
539_L546_R1.3280.99
568_R687_A1.3280.99
575_R701_C1.3260.99
525_K558_V1.3250.99
497_G510_H1.3210.99
63_G107_N1.3190.99
301_H567_C1.3160.99
569_M614_V1.3140.99
366_L385_A1.3110.99
360_L385_A1.3020.99
533_L661_V1.3010.99
367_L386_I1.2990.99
487_Y522_H1.2900.99
66_G240_F1.2870.99
442_Y472_A1.2850.99
344_V410_V1.2830.99
522_H656_F1.2810.99
374_L385_A1.2810.99
112_V120_L1.2740.99
332_I342_I1.2650.99
108_L243_D1.2650.99
282_D288_S1.2650.99
64_I242_I1.2640.99
95_E104_K1.2610.99
122_F241_V1.2510.99
576_E579_R1.2480.99
594_E609_M1.2470.99
273_L278_T1.2460.99
636_T665_D1.2440.99
395_C447_L1.2430.99
579_R585_T1.2400.99
279_T283_E1.2390.99
568_R671_L1.2290.99
480_G496_G1.2280.99
396_K454_D1.2270.99
614_V661_V1.2230.99
290_I303_F1.2210.99
242_I257_F1.2200.99
400_D403_K1.2190.99
517_N520_P1.2180.99
365_Y391_N1.2140.99
245_P253_R1.2080.99
579_R702_E1.2040.99
403_K455_T1.1990.99
401_K404_G1.1990.99
332_I410_V1.1970.99
278_T547_V1.1960.99
591_M604_L1.1940.99
654_H658_S1.1930.99
637_H642_D1.1930.99
258_T473_Q1.1910.99
364_G391_N1.1840.99
341_K411_D1.1830.98
552_D555_S1.1750.98
180_E217_S1.1750.98
663_V669_L1.1740.98
395_C399_A1.1740.98
244_G250_V1.1710.98
533_L659_L1.1670.98
97_T100_Y1.1640.98
572_Y670_A1.1600.98
56_R68_R1.1550.98
156_L162_V1.1530.98
199_F250_V1.1530.98
62_E107_N1.1490.98
343_C412_C1.1450.98
368_K374_L1.1400.98
564_Q674_N1.1400.98
294_A338_K1.1400.98
128_R131_G1.1370.98
298_L556_C1.1360.98
121_D129_I1.1340.98
81_H84_L1.1330.98
525_K529_A1.1230.98
271_L539_L1.1220.98
330_G333_R1.1210.98
181_T218_F1.1190.98
552_D556_C1.1190.98
102_E109_S1.1170.98
267_W412_C1.1170.98
497_G588_M1.1160.98
269_F573_L1.1160.98
487_Y622_E1.1140.98
555_S559_V1.1090.98
273_L293_M1.1050.98
594_E664_R1.1050.98
294_A340_L1.1040.98
522_H622_E1.1040.98
271_L537_S1.0980.98
628_F662_Y1.0970.98
524_Y539_L1.0940.97
260_R584_G1.0940.97
561_F658_S1.0940.97
422_P427_W1.0920.97
109_S126_G1.0870.97
129_I132_S1.0860.97
195_K468_A1.0840.97
595_F664_R1.0810.97
506_G580_A1.0760.97
479_W482_D1.0750.97
525_K559_V1.0750.97
558_V657_L1.0700.97
283_E545_Y1.0550.97
248_K585_T1.0510.97
712_F715_K1.0490.97
490_M530_F1.0430.97
402_L413_F1.0400.97
365_Y393_D1.0390.97
449_W453_K1.0390.97
290_I338_K1.0380.97
123_L128_R1.0370.97
594_E612_D1.0320.96
421_I427_W1.0300.96
478_H500_I1.0290.96
654_H662_Y1.0230.96
528_C539_L1.0210.96
92_V103_F1.0190.96
68_R236_Y1.0170.96
161_T603_Y1.0160.96
346_I402_L1.0150.96
677_R681_V1.0120.96
608_Y616_V1.0100.96
392_P396_K1.0090.96
363_K400_D1.0080.96
549_W552_D1.0070.96
57_F110_A1.0070.96
56_R70_E1.0060.96
395_C450_N1.0050.96
286_V342_I1.0040.96
274_T304_H1.0040.96
65_V92_V1.0030.96
283_E288_S1.0010.96
302_V341_K0.9990.96
562_F639_W0.9980.96
286_V303_F0.9960.96
59_S65_V0.9950.96
433_P437_H0.9950.96
490_M620_F0.9940.96
276_S308_F0.9940.96
185_D194_Y0.9930.96
124_R127_E0.9920.96
361_Q366_L0.9920.96
531_G537_S0.9890.95
334_R337_A0.9870.95
486_N489_S0.9870.95
65_V103_F0.9850.95
266_A574_Y0.9850.95
521_A552_D0.9800.95
466_R482_D0.9800.95
62_E106_G0.9770.95
305_F325_F0.9770.95
200_Y228_V0.9720.95
558_V656_F0.9720.95
124_R243_D0.9690.95
127_E132_S0.9680.95
639_W658_S0.9680.95
576_E701_C0.9670.95
704_P713_T0.9630.95
80_P83_P0.9600.95
367_L421_I0.9600.95
356_V401_K0.9600.95
317_D350_I0.9580.95
280_N324_T0.9570.95
498_L590_A0.9550.94
276_S345_W0.9540.94
712_F717_A0.9540.94
255_T506_G0.9530.94
96_N101_A0.9520.94
312_A323_L0.9510.94
619_V655_G0.9490.94
676_Q680_Y0.9480.94
442_Y475_F0.9470.94
335_L340_L0.9450.94
453_K711_I0.9450.94
123_L129_I0.9430.94
101_A114_K0.9430.94
524_Y559_V0.9420.94
255_T584_G0.9420.94
157_G204_R0.9420.94
493_S534_S0.9400.94
424_D427_W0.9400.94
580_A587_M0.9400.94
345_W414_K0.9390.94
64_I253_R0.9370.94
205_G245_P0.9310.94
576_E587_M0.9280.94
421_I425_V0.9250.94
487_Y490_M0.9250.94
501_G586_P0.9240.93
287_N338_K0.9210.93
644_L650_H0.9210.93
294_A301_H0.9210.93
598_D632_E0.9190.93
407_A455_T0.9180.93
113_S119_S0.9170.93
460_E706_A0.9150.93
548_P559_V0.9150.93
416_D482_D0.9150.93
333_R336_K0.9140.93
153_R229_Q0.9130.93
498_L588_M0.9110.93
311_K322_P0.9090.93
609_M613_N0.9090.93
125_N128_R0.9090.93
533_L565_L0.9020.93
200_Y220_V0.9010.93
306_D482_D0.9000.93
214_Q234_S0.9000.93
165_L220_V0.8980.92
116_E119_S0.8950.92
686_T705_A0.8920.92
307_C347_N0.8910.92
53_F69_I0.8900.92
336_K341_K0.8890.92
59_S105_S0.8890.92
480_G500_I0.8890.92
289_F549_W0.8880.92
413_F452_L0.8880.92
534_S588_M0.8860.92
212_H234_S0.8860.92
590_A593_M0.8840.92
57_F112_V0.8840.92
427_W433_P0.8820.92
314_Q317_D0.8820.92
306_D538_R0.8820.92
462_V477_V0.8790.92
376_Q385_A0.8790.92
559_V563_T0.8780.92
347_N417_F0.8770.92
580_A583_R0.8740.91
513_G524_Y0.8740.91
251_L593_M0.8720.91
288_S292_G0.8720.91
99_R114_K0.8720.91
252_D260_R0.8710.91
264_P577_A0.8710.91
350_I360_L0.8710.91
576_E580_A0.8700.91
263_L577_A0.8690.91
376_Q383_G0.8690.91
532_L562_F0.8670.91
561_F564_Q0.8670.91
502_L592_M0.8650.91
181_T196_N0.8640.91
480_G508_W0.8590.91
572_Y611_G0.8580.91
170_T174_R0.8550.91
95_E102_E0.8550.91
619_V624_G0.8540.90
197_I470_V0.8530.90
677_R680_Y0.8530.90
335_L342_I0.8500.90
102_E111_R0.8500.90
243_D253_R0.8490.90
465_A478_H0.8480.90
300_L303_F0.8480.90
637_H641_N0.8460.90
361_Q385_A0.8460.90
110_A122_F0.8450.90
296_R549_W0.8440.90
272_W302_V0.8420.90
79_G82_Y0.8410.90
248_K593_M0.8410.90
137_N140_V0.8400.90
613_N669_L0.8400.90
702_E722_T0.8400.90
442_Y474_K0.8400.90
307_C417_F0.8390.90
339_G680_Y0.8390.90
269_F587_M0.8380.90
688_F723_I0.8370.90
76_L80_P0.8350.89
348_P440_Y0.8350.89
273_L547_V0.8340.89
332_I408_M0.8330.89
399_A450_N0.8330.89
445_N476_P0.8330.89
395_C446_E0.8310.89
80_P84_L0.8270.89
441_A467_S0.8250.89
61_Q64_I0.8250.89
502_L590_A0.8220.89
83_P240_F0.8190.89
165_L200_Y0.8140.88
172_L498_L0.8130.88
511_D538_R0.8120.88
103_F110_A0.8110.88
264_P268_S0.8100.88
667_T670_A0.8100.88
217_S231_S0.8100.88
449_W711_I0.8090.88
360_L397_W0.8090.88
301_H678_P0.8070.88
557_D561_F0.8050.88
55_L118_W0.8040.88
57_F120_L0.8030.88
304_H536_H0.8030.88
58_F66_G0.8020.88
575_R703_V0.8010.87
482_D540_H0.8010.87
359_E400_D0.8000.87
453_K458_E0.8000.87
507_F577_A0.7970.87
310_M347_N0.7960.87
210_V216_V0.7960.87
722_T725_V0.7960.87
426_Q430_G0.7950.87
276_S347_N0.7920.87
154_L239_Y0.7920.87
357_F374_L0.7910.87
329_E407_A0.7910.87
293_M297_N0.7900.87
274_T540_H0.7900.87
172_L592_M0.7890.87
151_F231_S0.7870.87
127_E134_V0.7870.87
458_E712_F0.7870.87
261_P506_G0.7860.86
133_Q141_Q0.7830.86
264_P507_F0.7820.86
521_A555_S0.7810.86
564_Q676_Q0.7800.86
346_I405_L0.7800.86
479_W515_F0.7780.86
421_I424_D0.7770.86
638_L689_H0.7760.86
235_E435_K0.7760.86
127_E133_Q0.7750.86
609_M631_P0.7740.86
218_F230_F0.7710.85
195_K478_H0.7710.85
240_F257_F0.7700.85
165_L179_V0.7700.85
355_P359_E0.7640.85
604_L607_Q0.7640.85
472_A476_P0.7630.85
637_H662_Y0.7620.85
281_Y326_P0.7610.85
282_D287_N0.7610.85
420_R424_D0.7600.85
452_L461_A0.7600.85
466_R479_W0.7590.84
357_F361_Q0.7590.84
711_I714_L0.7580.84
99_R362_E0.7560.84
277_F308_F0.7560.84
556_C560_R0.7560.84
167_E496_G0.7550.84
418_G444_Y0.7550.84
472_A505_F0.7540.84
183_N467_S0.7530.84
273_L289_F0.7520.84
360_L365_Y0.7520.84
481_G515_F0.7510.84
138_G141_Q0.7510.84
707_D712_F0.7500.84
310_M313_F0.7500.84
289_F293_M0.7500.84
56_R75_A0.7500.84
654_H659_L0.7490.84
422_P426_Q0.7490.84
418_G465_A0.7480.84
233_E434_Q0.7480.84
152_E239_Y0.7470.84
197_I258_T0.7460.83
600_A629_Y0.7460.83
641_N689_H0.7450.83
68_R211_N0.7450.83
416_D466_R0.7440.83
406_V452_L0.7430.83
526_R529_A0.7430.83
113_S121_D0.7400.83
427_W430_G0.7400.83
468_A505_F0.7380.83
263_L574_Y0.7370.83
398_Y444_Y0.7370.83
267_W341_K0.7350.83
416_D515_F0.7320.82
422_P425_V0.7320.82
591_M601_C0.7310.82
553_D556_C0.7310.82
692_N725_V0.7310.82
133_Q137_N0.7310.82
576_E612_D0.7290.82
591_M631_P0.7270.82
263_L578_A0.7270.82
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497_G534_S0.7190.81
636_T643_E0.7180.81
258_T470_V0.7180.81
307_C310_M0.7180.81
530_F534_S0.7180.81
619_V623_A0.7150.81
477_V536_H0.7140.81
479_W540_H0.7140.81
194_Y481_G0.7140.81
721_N727_G0.7130.81
565_L661_V0.7110.80
161_T602_D0.7110.80
275_T306_D0.7110.80
480_G483_C0.7110.80
723_I728_A0.7110.80
356_V359_E0.7100.80
121_D128_R0.7100.80
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404_G407_A0.7080.80
519_A546_R0.7070.80
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591_M617_A0.7060.80
487_Y523_V0.7040.80
185_D417_F0.7030.80
134_V139_Y0.7030.80
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406_V409_G0.6950.79
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654_H660_P0.6240.71
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451_V454_D0.5850.66
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130_T133_Q0.5760.65
448_V463_L0.5760.65
629_Y632_E0.5750.65
402_L448_V0.5750.65
460_E574_Y0.5720.65
681_V684_E0.5710.64
61_Q256_R0.5710.64
598_D601_C0.5710.64
397_W401_K0.5700.64
636_T691_F0.5700.64
379_K387_Y0.5700.64
317_D444_Y0.5700.64
379_K386_I0.5690.64
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575_R578_A0.5690.64
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248_K579_R0.5680.64
511_D514_G0.5680.64
576_E589_R0.5680.64
91_K97_T0.5660.64
64_I256_R0.5660.64
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628_F649_W0.5650.64
276_S381_Q0.5640.63
345_W417_F0.5640.63
119_S135_K0.5640.63
271_L559_V0.5620.63
607_Q617_A0.5610.63
421_I430_G0.5610.63
185_D483_C0.5600.63
83_P87_L0.5600.63
585_T612_D0.5600.63
159_G599_P0.5590.63
197_I254_Y0.5590.63
107_N245_P0.5580.63
97_T102_E0.5580.63
266_A570_M0.5570.62
262_A449_W0.5570.62
287_N331_M0.5560.62
174_R499_S0.5560.62
359_E397_W0.5560.62
134_V138_G0.5560.62
88_Q95_E0.5560.62
514_G527_W0.5550.62
209_L254_Y0.5550.62
565_L638_L0.5540.62
716_A723_I0.5530.62
491_A606_R0.5520.62
483_C493_S0.5520.62
180_E215_C0.5520.62
272_W536_H0.5520.62
645_D648_R0.5510.62
479_W511_D0.5510.62
610_L616_V0.5500.62
347_N354_S0.5500.62
276_S536_H0.5500.62
501_G506_G0.5500.62
495_R498_L0.5500.62
182_W437_H0.5500.62
255_T504_G0.5500.62
360_L387_Y0.5490.61
80_P211_N0.5480.61
437_H441_A0.5480.61
412_C462_V0.5480.61
545_Y550_A0.5480.61
275_T347_N0.5480.61
251_L255_T0.5470.61
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388_D391_N0.5450.61
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563_T567_C0.5450.61
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606_R621_T0.5440.61
494_L608_Y0.5440.61
276_S542_S0.5410.60
588_M608_Y0.5410.60
703_V721_N0.5410.60
615_M630_L0.5410.60
308_F417_F0.5400.60
674_N684_E0.5390.60
533_L610_L0.5390.60
678_P682_W0.5380.60
643_E664_R0.5380.60
415_T448_V0.5370.60
275_T278_T0.5370.60
90_V98_E0.5340.59
276_S283_E0.5340.59
121_D135_K0.5340.59
271_L548_P0.5340.59
213_P436_M0.5330.59
485_A519_A0.5330.59
54_T74_G0.5330.59
668_L688_F0.5320.59
595_F633_G0.5320.59
403_K451_V0.5320.59
483_C489_S0.5320.59
425_V428_F0.5320.59
347_N418_G0.5320.59
516_E542_S0.5310.59
251_L502_L0.5300.59
347_N379_K0.5300.59
415_T496_G0.5300.59
263_L704_P0.5300.59
345_W482_D0.5300.59
210_V214_Q0.5290.59
294_A680_Y0.5290.59
89_D94_I0.5290.59
712_F716_A0.5280.58
171_A605_D0.5280.58
267_W302_V0.5280.58
700_V726_T0.5270.58
209_L264_P0.5250.58
172_L524_Y0.5250.58
172_L499_S0.5240.58
487_Y526_R0.5240.58
197_I473_Q0.5240.58
60_P240_F0.5220.58
331_M335_L0.5220.58
90_V115_G0.5220.58
306_D466_R0.5210.57
280_N283_E0.5210.57
414_K482_D0.5210.57
288_S291_D0.5200.57
185_D347_N0.5200.57
287_N291_D0.5190.57
716_A721_N0.5190.57
414_K480_G0.5190.57
93_T97_T0.5190.57
93_T96_N0.5180.57
344_V413_F0.5180.57
275_T542_S0.5180.57
62_E300_L0.5170.57
724_T727_G0.5170.57
426_Q432_D0.5170.57
94_I101_A0.5170.57
672_G676_Q0.5160.57
205_G250_V0.5160.57
364_G374_L0.5160.57
186_G190_T0.5150.57
54_T70_E0.5150.57
539_L548_P0.5150.57
609_M664_R0.5150.57
347_N414_K0.5150.57
607_Q618_P0.5120.56
389_F447_L0.5110.56
447_L450_N0.5110.56
70_E75_A0.5100.56
489_S492_E0.5100.56
414_K418_G0.5080.56
88_Q91_K0.5070.55
578_A581_N0.5070.55
339_G679_D0.5070.55
483_C490_M0.5060.55
576_E610_L0.5060.55
512_I528_C0.5060.55
45_T48_L0.5050.55
330_G337_A0.5050.55
414_K540_H0.5050.55
210_V239_Y0.5040.55
307_C343_C0.5040.55
355_P404_G0.5040.55
427_W437_H0.5040.55
551_Y559_V0.5040.55
638_L642_D0.5030.55
267_W389_F0.5030.55
632_E648_R0.5030.55
269_F574_Y0.5030.55
442_Y471_G0.5020.55
715_K722_T0.5020.55
477_V507_F0.5020.55
638_L687_A0.5010.55
301_H677_R0.5010.55
195_K417_F0.5010.55
567_C574_Y0.5010.55
57_F103_F0.5000.54
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ba0A 2 0.9352 100 0.163 Contact Map
3lppA 3 0.9611 100 0.171 Contact Map
3weoA 1 0.9521 100 0.172 Contact Map
3l4yA 1 0.9598 100 0.174 Contact Map
2f2hA 4 0.9858 100 0.183 Contact Map
3topA 1 0.9624 100 0.183 Contact Map
2xvlA 1 0.9352 100 0.192 Contact Map
4kmqA 1 0.956 100 0.23 Contact Map
4amwA 1 0.9715 100 0.232 Contact Map
3nsxA 2 0.7798 100 0.242 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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