GLMM - ECOLI - GREMLIN Contacts

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GLMM - Phosphoglucosamine mutase

UniProt:	P31120	Sequences: MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEAALGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11553
Length:	445 (432)
Sequences:	10929 (6764)
Seq/√Len:	325.4

ECOLI - GLMM MANB PGM
BACSU - GLMM PGCA
HALSA - Q9HN30 Q9HN85 Q9HR19
SULSO - Q980S1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
314_K	317_E	4.115	1.00
228_R	232_E	4.057	1.00
186_T	244_G	3.787	1.00
178_V	234_A	3.611	1.00
252_H	360_H	3.314	1.00
227_A	231_A	3.173	1.00
53_I	211_V	2.862	1.00
176_K	200_N	2.838	1.00
163_K	196_E	2.836	1.00
31_W	69_A	2.833	1.00
44_K	72_S	2.736	1.00
291_E	303_R	2.727	1.00
428_E	432_T	2.707	1.00
90_T	157_R	2.675	1.00
192_N	196_E	2.670	1.00
302_A	314_K	2.634	1.00
228_R	231_A	2.629	1.00
35_K	132_E	2.529	1.00
156_G	160_E	2.413	1.00
59_E	75_F	2.401	1.00
268_R	297_L	2.365	1.00
240_F	345_G	2.305	1.00
45_I	66_L	2.239	1.00
39_R	132_E	2.230	1.00
249_M	348_V	2.228	1.00
23_P	57_M	2.192	1.00
30_G	62_L	2.190	1.00
47_I	63_E	2.122	1.00
62_L	97_I	2.120	1.00
66_L	97_I	2.118	1.00
48_G	84_V	2.091	1.00
357_M	361_D	2.091	1.00
176_K	202_I	2.077	1.00
203_A	206_C	2.057	1.00
34_G	66_L	2.050	1.00
33_A	95_A	2.039	1.00
292_L	295_K	2.031	1.00
405_R	426_E	2.025	1.00
436_H	440_D	1.986	1.00
271_L	299_I	1.980	1.00
178_V	228_R	1.979	1.00
49_K	59_E	1.959	1.00
15_R	107_Y	1.958	1.00
49_K	55_G	1.949	1.00
46_I	93_A	1.948	1.00
268_R	272_R	1.938	1.00
56_Y	60_S	1.935	1.00
427_D	430_Q	1.892	1.00
268_R	365_G	1.869	1.00
128_A	131_A	1.864	1.00
291_E	295_K	1.864	1.00
432_T	436_H	1.863	1.00
131_A	135_K	1.859	1.00
34_G	69_A	1.847	1.00
132_E	135_K	1.846	1.00
35_K	69_A	1.802	1.00
156_G	192_N	1.801	1.00
86_Y	90_T	1.766	1.00
33_A	113_F	1.747	1.00
39_R	128_A	1.731	1.00
121_L	129_I	1.721	1.00
265_I	351_A	1.715	1.00
159_I	193_V	1.704	1.00
430_Q	433_E	1.704	1.00
44_K	74_L	1.703	1.00
431_V	435_A	1.687	1.00
31_W	35_K	1.684	1.00
15_R	108_D	1.677	1.00
255_N	364_S	1.676	1.00
238_I	345_G	1.672	1.00
314_K	318_K	1.671	1.00
396_A	399_E	1.624	1.00
397_E	400_A	1.616	1.00
27_L	61_A	1.616	1.00
202_I	232_E	1.614	1.00
160_E	196_E	1.602	1.00
433_E	437_R	1.598	1.00
130_E	134_E	1.553	1.00
292_L	369_F	1.546	1.00
358_S	361_D	1.544	1.00
423_V	435_A	1.543	1.00
252_H	358_S	1.543	1.00
294_L	299_I	1.525	1.00
380_A	383_G	1.520	1.00
393_A	397_E	1.506	1.00
313_E	317_E	1.497	1.00
227_A	230_L	1.496	1.00
296_Q	365_G	1.487	1.00
192_N	195_R	1.482	1.00
191_P	195_R	1.464	1.00
210_G	213_I	1.447	1.00
253_E	360_H	1.438	1.00
279_G	300_P	1.437	1.00
42_S	72_S	1.432	1.00
181_C	206_C	1.425	1.00
26_V	111_I	1.419	1.00
15_R	18_D	1.418	1.00
429_A	433_E	1.417	1.00
43_R	94_E	1.409	1.00
44_K	94_E	1.408	1.00
66_L	71_L	1.407	1.00
27_L	64_A	1.396	1.00
51_T	78_P	1.394	1.00
156_G	196_E	1.389	1.00
391_V	394_V	1.388	1.00
282_G	301_F	1.383	1.00
311_V	323_G	1.377	1.00
191_P	206_C	1.371	1.00
263_M	324_A	1.367	1.00
27_L	68_A	1.364	1.00
16_V	54_S	1.360	1.00
304_A	314_K	1.355	1.00
86_Y	161_F	1.355	1.00
46_I	87_L	1.354	1.00
266_I	332_L	1.348	1.00
357_M	365_G	1.346	1.00
229_V	237_G	1.344	1.00
396_A	400_A	1.338	1.00
223_R	226_Q	1.333	1.00
36_V	125_V	1.331	1.00
125_V	128_A	1.328	1.00
177_I	236_L	1.326	1.00
272_R	355_N	1.319	1.00
49_K	56_Y	1.304	1.00
34_G	71_L	1.295	1.00
40_H	128_A	1.288	1.00
175_L	235_D	1.278	1.00
26_V	58_L	1.276	1.00
36_V	132_E	1.275	1.00
361_D	364_S	1.272	1.00
53_I	210_G	1.268	1.00
300_P	318_K	1.263	1.00
176_K	232_E	1.259	1.00
267_A	280_A	1.257	1.00
12_I	29_L	1.253	1.00
63_E	67_A	1.253	1.00
432_T	435_A	1.252	1.00
30_G	111_I	1.246	1.00
145_L	149_S	1.246	1.00
435_A	439_A	1.243	1.00
6_Y	134_E	1.241	1.00
236_L	349_L	1.235	1.00
222_V	256_K	1.235	1.00
205_G	224_A	1.233	1.00
131_A	134_E	1.231	1.00
425_G	431_V	1.229	1.00
215_A	218_G	1.225	1.00
162_C	343_V	1.220	1.00
430_Q	434_F	1.216	1.00
269_E	354_R	1.210	1.00
165_T	347_Q	1.204	1.00
225_L	239_A	1.200	1.00
49_K	75_F	1.196	1.00
355_N	358_S	1.190	1.00
273_Q	354_R	1.181	1.00
79_M	83_A	1.177	1.00
66_L	73_A	1.176	1.00
162_C	346_L	1.174	1.00
230_L	253_E	1.169	1.00
236_L	352_M	1.163	1.00
36_V	128_A	1.162	1.00
30_G	66_L	1.159	1.00
161_F	164_A	1.157	1.00
122_P	125_V	1.156	1.00
47_I	62_L	1.153	1.00
157_R	160_E	1.146	1.00
155_A	189_I	1.143	1.00
197_L	346_L	1.140	1.00
302_A	318_K	1.136	1.00
45_I	95_A	1.135	1.00
43_R	71_L	1.133	1.00
128_A	132_E	1.132	1.00
176_K	233_K	1.129	1.00
142_S	145_L	1.128	1.00
160_E	164_A	1.126	1.00
269_E	273_Q	1.124	1.00
264_Y	289_G	1.120	1.00
374_V	436_H	1.115	1.00
390_S	394_V	1.115	1.00
426_E	430_Q	1.109	1.00
405_R	430_Q	1.107	1.00
153_D	156_G	1.104	1.00
194_L	345_G	1.097	1.00
59_E	63_E	1.092	1.00
238_I	249_M	1.090	1.00
88_T	96_G	1.087	1.00
124_A	128_A	1.086	1.00
282_G	286_S	1.084	1.00
282_G	303_R	1.077	1.00
90_T	161_F	1.075	1.00
225_L	250_V	1.075	1.00
352_M	362_L	1.070	1.00
97_I	111_I	1.068	1.00
264_Y	293_A	1.067	1.00
62_L	99_I	1.065	1.00
63_E	75_F	1.065	1.00
33_A	97_I	1.062	1.00
155_A	192_N	1.061	1.00
12_I	113_F	1.060	1.00
389_E	393_A	1.059	1.00
271_L	279_G	1.056	1.00
91_F	154_A	1.047	1.00
84_V	98_V	1.046	1.00
86_Y	157_R	1.043	1.00
350_A	354_R	1.043	1.00
286_S	290_L	1.041	1.00
251_D	255_N	1.040	1.00
161_F	165_T	1.040	1.00
390_S	393_A	1.039	1.00
23_P	61_A	1.038	1.00
61_A	65_G	1.037	1.00
67_A	149_S	1.034	1.00
204_I	228_R	1.033	1.00
159_I	196_E	1.031	1.00
392_K	396_A	1.031	1.00
293_A	297_L	1.031	1.00
291_E	301_F	1.030	1.00
179_V	194_L	1.029	1.00
94_E	116_I	1.027	1.00
32_A	133_M	1.027	1.00
167_P	350_A	1.026	1.00
372_I	432_T	1.023	1.00
202_I	234_A	1.022	1.00
289_G	362_L	1.019	1.00
48_G	98_V	1.015	1.00
84_V	96_G	1.014	1.00
127_E	130_E	1.008	1.00
80_P	83_A	1.004	1.00
159_I	189_I	1.002	1.00
31_W	68_A	1.000	1.00
137_I	140_V	1.000	1.00
187_Y	206_C	0.998	1.00
127_E	131_A	0.997	1.00
310_Y	313_E	0.997	1.00
186_T	240_F	0.992	1.00
194_L	349_L	0.992	1.00
179_V	186_T	0.989	1.00
38_A	71_L	0.987	1.00
226_Q	230_L	0.982	1.00
378_Y	383_G	0.982	1.00
62_L	66_L	0.979	1.00
398_V	434_F	0.978	1.00
271_L	297_L	0.977	1.00
221_D	224_A	0.976	1.00
187_Y	191_P	0.976	1.00
205_G	217_V	0.975	1.00
195_R	203_A	0.974	1.00
175_L	352_M	0.973	1.00
51_T	208_P	0.971	1.00
141_D	144_E	0.960	1.00
332_L	347_Q	0.960	1.00
76_T	79_M	0.957	1.00
60_S	64_A	0.955	1.00
374_V	439_A	0.953	1.00
179_V	240_F	0.951	1.00
294_L	301_F	0.950	1.00
178_V	202_I	0.942	1.00
146_G	149_S	0.941	1.00
275_Q	278_G	0.941	1.00
54_S	57_M	0.940	1.00
178_V	232_E	0.938	1.00
160_E	163_K	0.938	1.00
315_M	320_W	0.932	1.00
263_M	290_L	0.929	1.00
32_A	132_E	0.927	1.00
59_E	99_I	0.927	1.00
115_S	125_V	0.924	1.00
292_L	296_Q	0.924	1.00
333_L	337_T	0.923	1.00
229_V	250_V	0.920	1.00
64_A	68_A	0.909	1.00
138_S	141_D	0.908	1.00
394_V	397_E	0.907	1.00
25_F	29_L	0.902	1.00
55_G	109_N	0.897	1.00
202_I	228_R	0.894	1.00
141_D	145_L	0.893	1.00
261_Q	368_M	0.893	1.00
222_V	225_L	0.892	1.00
280_A	294_L	0.889	1.00
87_L	154_A	0.889	1.00
121_L	125_V	0.887	1.00
154_A	157_R	0.886	1.00
265_I	363_C	0.884	1.00
46_I	76_T	0.882	1.00
176_K	235_D	0.881	1.00
38_A	43_R	0.880	1.00
183_N	205_G	0.879	1.00
163_K	197_L	0.877	1.00
351_A	355_N	0.877	1.00
123_D	310_Y	0.873	1.00
322_I	330_V	0.870	1.00
261_Q	363_C	0.870	1.00
360_H	364_S	0.868	1.00
262_I	330_V	0.868	1.00
249_M	262_I	0.866	1.00
270_G	347_Q	0.864	1.00
319_G	333_L	0.863	1.00
221_D	225_L	0.862	1.00
262_I	348_V	0.860	1.00
359_L	363_C	0.858	1.00
376_V	439_A	0.858	1.00
49_K	78_P	0.857	1.00
77_G	188_H	0.856	1.00
272_R	297_L	0.847	1.00
79_M	98_V	0.845	1.00
29_L	133_M	0.844	1.00
130_E	133_M	0.843	1.00
230_L	233_K	0.841	1.00
280_A	290_L	0.841	1.00
190_A	240_F	0.840	1.00
388_H	391_V	0.839	1.00
398_V	401_A	0.839	1.00
226_Q	256_K	0.839	1.00
293_A	296_Q	0.833	1.00
23_P	27_L	0.832	1.00
431_V	434_F	0.830	1.00
238_I	247_V	0.830	1.00
40_H	125_V	0.828	1.00
30_G	65_G	0.826	1.00
436_H	439_A	0.825	1.00
177_I	349_L	0.825	1.00
140_V	145_L	0.823	1.00
37_L	95_A	0.823	1.00
421_V	439_A	0.821	1.00
222_V	248_I	0.820	1.00
251_D	360_H	0.819	1.00
372_I	435_A	0.816	1.00
189_I	342_I	0.811	1.00
296_Q	369_F	0.811	1.00
190_A	342_I	0.811	1.00
175_L	349_L	0.810	1.00
48_G	79_M	0.807	1.00
247_V	344_A	0.806	1.00
72_S	150_R	0.801	1.00
349_L	352_M	0.800	1.00
347_Q	350_A	0.799	1.00
216_E	221_D	0.798	1.00
139_C	142_S	0.798	1.00
177_I	199_A	0.797	1.00
268_R	366_M	0.796	1.00
305_K	310_Y	0.795	1.00
121_L	126_E	0.795	1.00
35_K	39_R	0.795	1.00
287_N	324_A	0.793	1.00
74_L	93_A	0.791	1.00
389_E	392_K	0.790	1.00
263_M	280_A	0.790	1.00
48_G	76_T	0.788	1.00
330_V	344_A	0.786	1.00
268_R	293_A	0.783	1.00
205_G	214_N	0.782	1.00
295_K	301_F	0.781	1.00
334_D	337_T	0.780	1.00
382_S	386_L	0.779	1.00
78_P	185_A	0.777	1.00
269_E	351_A	0.777	1.00
238_I	349_L	0.775	1.00
425_G	430_Q	0.775	1.00
38_A	69_A	0.775	1.00
166_F	346_L	0.771	1.00
264_Y	287_N	0.770	1.00
88_T	95_A	0.769	1.00
51_T	185_A	0.766	1.00
240_F	341_G	0.766	1.00
282_G	291_E	0.764	1.00
123_D	126_E	0.764	1.00
155_A	188_H	0.763	1.00
381_G	385_P	0.763	1.00
126_E	129_I	0.760	0.99
10_D	283_T	0.759	0.99
266_I	351_A	0.758	0.99
225_L	237_G	0.758	0.99
220_T	224_A	0.757	0.99
250_V	256_K	0.756	0.99
262_I	266_I	0.755	0.99
281_V	323_G	0.752	0.99
44_K	93_A	0.750	0.99
152_V	156_G	0.749	0.99
321_R	334_D	0.749	0.99
74_L	152_V	0.749	0.99
378_Y	381_G	0.747	0.99
357_M	362_L	0.747	0.99
30_G	34_G	0.746	0.99
140_V	146_G	0.745	0.99
83_A	155_A	0.745	0.99
401_A	437_R	0.743	0.99
290_L	324_A	0.742	0.99
437_R	440_D	0.741	0.99
24_D	28_K	0.740	0.99
284_L	409_L	0.740	0.99
153_D	157_R	0.739	0.99
61_A	64_A	0.739	0.99
143_A	146_G	0.738	0.99
281_V	314_K	0.735	0.99
67_A	148_A	0.733	0.99
90_T	154_A	0.731	0.99
392_K	397_E	0.728	0.99
329_H	339_G	0.727	0.99
106_F	211_V	0.727	0.99
312_L	331_I	0.727	0.99
36_V	40_H	0.726	0.99
401_A	433_E	0.725	0.99
434_F	437_R	0.723	0.99
423_V	431_V	0.721	0.99
223_R	227_A	0.719	0.99
113_F	129_I	0.719	0.99
429_A	432_T	0.716	0.99
247_V	341_G	0.715	0.99
216_E	219_A	0.714	0.99
295_K	300_P	0.713	0.99
178_V	237_G	0.712	0.99
71_L	94_E	0.712	0.99
406_G	425_G	0.712	0.99
288_M	424_E	0.711	0.99
370_P	428_E	0.711	0.99
156_G	159_I	0.711	0.99
167_P	170_L	0.709	0.99
179_V	190_A	0.709	0.99
215_A	221_D	0.708	0.99
87_L	91_F	0.705	0.99
229_V	234_A	0.705	0.99
236_L	249_M	0.702	0.99
215_A	219_A	0.702	0.99
145_L	148_A	0.701	0.99
388_H	393_A	0.701	0.99
46_I	91_F	0.701	0.99
188_H	192_N	0.701	0.99
183_N	214_N	0.699	0.99
255_N	261_Q	0.699	0.99
175_L	236_L	0.697	0.99
35_K	38_A	0.696	0.99
371_Q	375_N	0.696	0.99
201_V	206_C	0.694	0.99
76_T	83_A	0.694	0.99
159_I	192_N	0.693	0.99
63_E	73_A	0.692	0.99
222_V	226_Q	0.692	0.99
248_I	256_K	0.691	0.99
174_E	200_N	0.691	0.99
266_I	347_Q	0.689	0.99
382_S	385_P	0.689	0.99
159_I	163_K	0.688	0.99
172_L	199_A	0.686	0.99
173_S	200_N	0.686	0.99
125_V	129_I	0.685	0.99
143_A	147_K	0.682	0.99
218_G	221_D	0.682	0.99
30_G	97_I	0.682	0.99
408_V	438_I	0.681	0.99
255_N	363_C	0.680	0.99
257_V	359_L	0.679	0.99
9_T	414_G	0.678	0.99
204_I	227_A	0.676	0.99
434_F	438_I	0.674	0.99
103_H	112_K	0.672	0.99
399_E	407_R	0.667	0.99
91_F	157_R	0.666	0.99
191_P	203_A	0.666	0.99
175_L	353_A	0.665	0.99
263_M	322_I	0.665	0.99
17_G	57_M	0.662	0.99
124_A	127_E	0.662	0.99
129_I	133_M	0.661	0.99
247_V	345_G	0.659	0.99
183_N	217_V	0.658	0.99
194_L	199_A	0.657	0.99
382_S	412_K	0.654	0.98
290_L	301_F	0.653	0.98
348_V	359_L	0.652	0.98
119_T	316_Q	0.651	0.98
237_G	250_V	0.649	0.98
79_M	155_A	0.649	0.98
221_D	226_Q	0.649	0.98
8_G	11_G	0.648	0.98
274_G	278_G	0.643	0.98
397_E	401_A	0.643	0.98
161_F	335_K	0.641	0.98
387_E	390_S	0.640	0.98
271_L	294_L	0.638	0.98
274_G	321_R	0.637	0.98
383_G	386_L	0.637	0.98
28_K	133_M	0.636	0.98
158_Y	162_C	0.634	0.98
399_E	402_L	0.632	0.98
15_R	20_P	0.630	0.98
427_D	431_V	0.630	0.98
166_F	170_L	0.630	0.98
53_I	106_F	0.630	0.98
137_I	142_S	0.630	0.98
352_M	355_N	0.630	0.98
274_G	279_G	0.628	0.98
33_A	37_L	0.625	0.98
117_D	316_Q	0.625	0.98
296_Q	366_M	0.620	0.98
64_A	67_A	0.620	0.98
285_M	306_V	0.619	0.98
137_I	145_L	0.619	0.98
17_G	22_T	0.618	0.98
18_D	107_Y	0.617	0.98
266_I	344_A	0.616	0.98
381_G	384_D	0.615	0.98
297_L	366_M	0.613	0.98
380_A	384_D	0.611	0.98
55_G	59_E	0.610	0.98
388_H	392_K	0.610	0.98
268_R	362_L	0.610	0.98
176_K	234_A	0.609	0.98
395_T	410_L	0.608	0.98
26_V	30_G	0.607	0.98
25_F	133_M	0.606	0.98
279_G	302_A	0.606	0.98
155_A	159_I	0.604	0.97
267_A	290_L	0.603	0.97
26_V	61_A	0.603	0.97
190_A	345_G	0.601	0.97
389_E	394_V	0.600	0.97
393_A	396_A	0.600	0.97
29_L	113_F	0.600	0.97
17_G	20_P	0.599	0.97
126_E	130_E	0.599	0.97
249_M	359_L	0.598	0.97
167_P	354_R	0.596	0.97
148_A	151_I	0.596	0.97
142_S	146_G	0.596	0.97
190_A	194_L	0.596	0.97
363_C	366_M	0.595	0.97
438_I	441_A	0.595	0.97
384_D	412_K	0.595	0.97
143_A	148_A	0.595	0.97
56_Y	77_G	0.594	0.97
395_T	398_V	0.593	0.97
282_G	288_M	0.592	0.97
33_A	45_I	0.592	0.97
378_Y	384_D	0.592	0.97
378_Y	412_K	0.591	0.97
379_T	382_S	0.591	0.97
76_T	84_V	0.590	0.97
267_A	322_I	0.590	0.97
209_N	215_A	0.589	0.97
395_T	399_E	0.588	0.97
10_D	373_L	0.588	0.97
101_A	104_N	0.586	0.97
224_A	227_A	0.586	0.97
27_L	31_W	0.586	0.97
292_L	426_E	0.584	0.97
27_L	65_G	0.583	0.97
165_T	343_V	0.582	0.97
181_C	204_I	0.582	0.97
187_Y	208_P	0.582	0.97
104_N	415_T	0.581	0.97
322_I	332_L	0.581	0.97
28_K	134_E	0.581	0.97
144_E	147_K	0.581	0.97
372_I	439_A	0.579	0.97
378_Y	386_L	0.579	0.97
352_M	359_L	0.578	0.97
257_V	265_I	0.577	0.97
430_Q	437_R	0.576	0.97
437_R	441_A	0.576	0.97
180_D	239_A	0.576	0.97
270_G	275_Q	0.576	0.97
57_M	61_A	0.575	0.97
102_S	112_K	0.575	0.97
401_A	434_F	0.575	0.97
257_V	363_C	0.575	0.97
212_N	217_V	0.574	0.97
235_D	252_H	0.573	0.97
394_V	398_V	0.573	0.97
67_A	73_A	0.573	0.97
122_P	126_E	0.570	0.96
22_T	25_F	0.569	0.96
255_N	360_H	0.569	0.96
138_S	142_S	0.568	0.96
220_T	225_L	0.568	0.96
10_D	120_K	0.567	0.96
375_N	418_L	0.564	0.96
172_L	353_A	0.564	0.96
45_I	71_L	0.563	0.96
264_Y	268_R	0.563	0.96
147_K	151_I	0.561	0.96
228_R	234_A	0.560	0.96
8_G	414_G	0.560	0.96
35_K	135_K	0.559	0.96
379_T	383_G	0.558	0.96
83_A	189_I	0.556	0.96
282_G	290_L	0.556	0.96
288_M	292_L	0.555	0.96
170_L	353_A	0.554	0.96
28_K	31_W	0.552	0.96
239_A	250_V	0.549	0.96
281_V	304_A	0.548	0.96
287_N	407_R	0.546	0.95
179_V	201_V	0.546	0.95
377_R	418_L	0.545	0.95
266_I	348_V	0.544	0.95
104_N	108_D	0.544	0.95
271_L	275_Q	0.543	0.95
302_A	320_W	0.543	0.95
253_E	364_S	0.541	0.95
195_R	200_N	0.541	0.95
392_K	398_V	0.541	0.95
139_C	145_L	0.541	0.95
62_L	111_I	0.540	0.95
139_C	144_E	0.540	0.95
203_A	207_E	0.539	0.95
85_A	337_T	0.538	0.95
23_P	64_A	0.537	0.95
140_V	144_E	0.537	0.95
225_L	256_K	0.536	0.95
374_V	435_A	0.536	0.95
274_G	277_R	0.536	0.95
281_V	311_V	0.533	0.95
171_S	353_A	0.533	0.95
403_G	406_G	0.533	0.95
277_R	299_I	0.532	0.95
406_G	434_F	0.531	0.95
262_I	328_G	0.531	0.95
252_H	361_D	0.531	0.95
26_V	62_L	0.530	0.95
407_R	424_E	0.529	0.95
38_A	41_G	0.529	0.95
308_D	339_G	0.527	0.95
247_V	348_V	0.524	0.94
208_P	212_N	0.524	0.94
258_D	261_Q	0.524	0.94
21_I	25_F	0.522	0.94
190_A	201_V	0.522	0.94
277_R	321_R	0.518	0.94
354_R	358_S	0.518	0.94
428_E	431_V	0.516	0.94
120_K	126_E	0.515	0.94
181_C	187_Y	0.514	0.94
64_A	139_C	0.514	0.94
174_E	353_A	0.514	0.94
399_E	409_L	0.513	0.94
288_M	369_F	0.512	0.94
391_V	397_E	0.509	0.93
104_N	112_K	0.507	0.93
72_S	147_K	0.505	0.93
42_S	94_E	0.505	0.93
289_G	369_F	0.503	0.93
209_N	213_I	0.502	0.93
13_R	103_H	0.502	0.93
103_H	245_D	0.502	0.93
433_E	436_H	0.501	0.93
255_N	368_M	0.500	0.93
142_S	149_S	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pdkA	2	0.9843	100	0.09	Contact Map
2f7lA	4	0.9865	100	0.091	Contact Map
1wqaA	3	0.9843	100	0.092	Contact Map
3i3wA	2	0.9843	100	0.095	Contact Map
1tuoA	1	0.9371	100	0.109	Contact Map
3uw2A	1	0.9573	100	0.13	Contact Map
1p5dX	1	0.973	100	0.136	Contact Map
3na5A	2	0.9933	100	0.141	Contact Map
2z0fA	2	0.9506	100	0.142	Contact Map
4hjhA	2	0.9551	100	0.177	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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