GREMLIN Database
AAS - Bifunctional protein Aas
UniProt: P31119 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11679
Length: 719 (546)
Sequences: 11287 (9312)
Seq/√Len: 398.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
367_E384_V4.8871.00
637_S673_Y4.3911.00
556_L599_V3.7241.00
257_R283_A3.5081.00
255_G366_E3.1821.00
386_S565_N3.1591.00
238_L277_A2.9381.00
408_R434_E2.8331.00
255_G565_N2.8131.00
204_E212_S2.8071.00
247_I251_Y2.7491.00
285_M294_L2.7211.00
545_L557_Q2.6411.00
300_A372_F2.6341.00
145_F161_T2.5641.00
238_L357_L2.5311.00
213_A217_F2.4911.00
600_R608_Q2.4601.00
506_R524_V2.4571.00
242_L277_A2.4251.00
253_V280_R2.3821.00
256_E304_K2.3571.00
521_S542_A2.3471.00
235_R239_T2.3171.00
572_K575_V2.3141.00
154_R158_P2.2851.00
553_G610_Q2.2831.00
259_G303_I2.2351.00
213_A216_R2.1731.00
225_E228_N2.1491.00
386_S389_S2.1371.00
660_T688_I2.1371.00
296_S379_H2.1361.00
224_V434_E2.1301.00
449_E453_D2.1091.00
464_T489_E2.1061.00
217_F220_G2.0861.00
389_S517_A2.0861.00
211_L238_L2.0781.00
182_R186_G2.0711.00
257_R370_I2.0661.00
542_A558_L2.0651.00
221_K231_P2.0601.00
523_N606_F2.0211.00
224_V454_R2.0151.00
602_D608_Q2.0151.00
244_V270_A2.0061.00
174_D177_R1.9971.00
544_L599_V1.9881.00
407_D457_T1.9871.00
253_V256_E1.9781.00
660_T690_Y1.9691.00
439_P442_L1.9691.00
553_G598_I1.9681.00
399_T538_P1.9641.00
630_E645_A1.9311.00
541_D583_N1.9251.00
602_D606_F1.9201.00
145_F157_F1.9141.00
661_T694_M1.9111.00
541_D559_K1.9101.00
268_S415_L1.8761.00
257_R281_M1.8681.00
254_E366_E1.8611.00
367_E565_N1.8521.00
219_A235_R1.8381.00
544_L607_V1.8251.00
559_K592_W1.8241.00
365_E386_S1.7991.00
658_L688_I1.7891.00
153_K156_L1.7891.00
370_I568_L1.7771.00
205_T208_E1.7671.00
442_L446_I1.7651.00
363_Q366_E1.7511.00
615_R704_F1.7301.00
251_Y329_R1.7251.00
165_L169_Q1.7011.00
648_S651_S1.7001.00
241_T277_A1.6911.00
186_G189_L1.6891.00
210_L273_F1.6821.00
523_N532_T1.6791.00
443_H446_I1.6651.00
185_A189_L1.6631.00
408_R456_C1.6601.00
436_F456_C1.6561.00
181_R185_A1.6511.00
271_V307_F1.6441.00
644_T694_M1.6421.00
295_T299_T1.6401.00
365_E388_K1.6381.00
204_E208_E1.6321.00
238_L242_L1.6281.00
659_F708_K1.6271.00
298_I303_I1.6261.00
392_A539_G1.6191.00
244_V274_G1.6161.00
583_N590_R1.6091.00
212_S216_R1.6051.00
260_L271_V1.6011.00
256_E280_R1.6011.00
187_E191_Q1.5961.00
555_R594_D1.5901.00
450_L454_R1.5901.00
182_R189_L1.5881.00
460_F519_V1.5771.00
246_R358_A1.5771.00
309_S312_F1.5691.00
147_R157_F1.5681.00
225_E266_G1.5651.00
159_Q163_H1.5561.00
296_S372_F1.5551.00
242_L246_R1.5531.00
617_A626_L1.5371.00
152_V157_F1.5241.00
211_L277_A1.5211.00
225_E229_F1.5201.00
232_D270_A1.5201.00
644_T702_P1.5121.00
622_E682_L1.5081.00
619_I647_K1.4961.00
407_D482_R1.4921.00
232_D266_G1.4901.00
224_V231_P1.4891.00
485_V510_G1.4851.00
648_S654_E1.4831.00
632_L678_G1.4791.00
657_V689_R1.4791.00
436_F450_L1.4791.00
408_R436_F1.4781.00
421_L460_F1.4771.00
182_R185_A1.4751.00
310_R335_D1.4691.00
188_M192_I1.4681.00
414_P418_S1.4681.00
438_Y450_L1.4641.00
225_E230_T1.4281.00
586_G590_R1.4191.00
221_K224_V1.4061.00
240_K267_I1.4041.00
207_Y387_H1.4021.00
291_V295_T1.4021.00
183_K186_G1.3991.00
635_G642_H1.3981.00
636_V678_G1.3961.00
398_K431_T1.3961.00
542_A556_L1.3951.00
455_S480_R1.3921.00
186_G190_H1.3821.00
393_N519_V1.3811.00
221_K434_E1.3771.00
289_A297_A1.3751.00
276_I368_A1.3711.00
645_A658_L1.3691.00
362_Q366_E1.3661.00
647_K654_E1.3621.00
389_S563_I1.3581.00
691_L694_M1.3571.00
659_F710_W1.3541.00
300_A572_K1.3481.00
158_P162_L1.3461.00
209_S391_L1.3311.00
460_F487_G1.3261.00
383_V564_M1.3261.00
207_Y362_Q1.3191.00
228_N439_P1.3171.00
300_A379_H1.3161.00
151_L156_L1.3151.00
598_I613_A1.3121.00
189_L193_M1.3111.00
510_G519_V1.3101.00
520_V558_L1.2971.00
542_A599_V1.2901.00
206_L390_I1.2891.00
666_T669_K1.2871.00
181_R189_L1.2851.00
460_F510_G1.2791.00
458_V483_Y1.2771.00
291_V315_K1.2721.00
283_A301_A1.2681.00
299_T379_H1.2671.00
166_P170_V1.2661.00
163_H185_A1.2651.00
393_N518_P1.2611.00
573_P577_E1.2491.00
413_L421_L1.2451.00
250_K353_L1.2441.00
673_Y678_G1.2441.00
632_L674_A1.2431.00
394_V430_L1.2421.00
193_M601_F1.2411.00
187_E192_I1.2401.00
193_M550_I1.2401.00
263_P309_S1.2371.00
407_D433_A1.2331.00
385_H564_M1.2321.00
583_N592_W1.2251.00
667_R688_I1.2191.00
260_L272_I1.2111.00
508_L524_V1.2011.00
310_R334_E1.2001.00
289_A418_S1.1971.00
398_K427_T1.1941.00
238_L241_T1.1921.00
516_C520_V1.1921.00
543_R585_R1.1921.00
557_Q594_D1.1911.00
233_S236_K1.1881.00
148_L151_L1.1841.00
211_L241_T1.1781.00
410_M438_Y1.1761.00
703_D706_T1.1721.00
281_M367_E1.1681.00
627_E630_E1.1681.00
310_R332_Y1.1661.00
626_L645_A1.1651.00
230_T266_G1.1641.00
269_A425_L1.1641.00
223_C266_G1.1621.00
267_I309_S1.1591.00
424_G460_F1.1581.00
543_R583_N1.1571.00
581_A592_W1.1501.00
492_Q495_T1.1471.00
575_V579_P1.1441.00
537_L540_M1.1431.00
301_A372_F1.1431.00
483_Y508_L1.1401.00
207_Y276_I1.1341.00
671_Q688_I1.1331.00
181_R184_I1.1301.00
471_R498_L1.1261.00
564_M580_T1.1261.00
210_L214_M1.1221.00
411_S437_L1.1221.00
274_G278_R1.1191.00
550_I601_F1.1171.00
393_N487_G1.1101.00
467_G495_T1.1021.00
157_F160_I1.0991.00
619_I654_E1.0971.00
587_E590_R1.0941.00
499_W507_I1.0891.00
148_L156_L1.0881.00
271_V275_A1.0871.00
214_M238_L1.0861.00
181_R186_G1.0851.00
251_Y305_T1.0801.00
615_R630_E1.0771.00
540_M562_N1.0741.00
655_A687_D1.0731.00
246_R354_M1.0711.00
230_T240_K1.0711.00
208_E211_L1.0681.00
487_G519_V1.0641.00
253_V258_I1.0631.00
407_D458_V1.0631.00
221_K233_S1.0601.00
336_L340_V1.0601.00
308_T312_F1.0601.00
403_F433_A1.0551.00
467_G492_Q1.0521.00
210_L238_L1.0511.00
428_P433_A1.0501.00
385_H517_A1.0441.00
255_G367_E1.0431.00
535_R606_F1.0421.00
446_I449_E1.0411.00
160_I163_H1.0351.00
209_S395_E1.0331.00
147_R152_V1.0301.00
384_V568_L1.0281.00
516_C558_L1.0241.00
553_G613_A1.0211.00
486_A491_L1.0211.00
388_K561_P1.0181.00
293_G628_M1.0141.00
292_K296_S1.0121.00
249_E353_L1.0121.00
466_L486_A1.0101.00
493_E497_Q1.0091.00
491_L509_E1.0081.00
184_I187_E1.0081.00
247_I250_K1.0081.00
671_Q675_R1.0061.00
223_C269_A1.0061.00
335_D338_A1.0021.00
247_I331_V1.0001.00
313_L332_Y0.9981.00
394_V427_T0.9931.00
500_Q527_A0.9911.00
484_V499_W0.9881.00
392_A561_P0.9881.00
410_M451_V0.9871.00
659_F707_L0.9861.00
296_S300_A0.9841.00
272_I425_L0.9831.00
337_K340_V0.9821.00
672_Q676_E0.9821.00
404_T407_D0.9801.00
650_A653_G0.9781.00
533_V609_I0.9781.00
332_Y335_D0.9771.00
669_K672_Q0.9731.00
537_L562_N0.9711.00
490_K609_I0.9701.00
412_A462_T0.9701.00
635_G643_A0.9691.00
354_M358_A0.9671.00
646_I659_F0.9661.00
240_K243_F0.9661.00
673_Y676_E0.9641.00
239_T355_P0.9611.00
467_G494_S0.9591.00
520_V540_M0.9571.00
423_V518_P0.9541.00
369_L385_H0.9471.00
460_F463_S0.9471.00
263_P311_Q0.9471.00
162_L182_R0.9471.00
413_L460_F0.9461.00
393_N460_F0.9461.00
670_L688_I0.9441.00
660_T670_L0.9401.00
161_T165_L0.9381.00
412_A461_G0.9361.00
200_V539_G0.9361.00
491_L507_I0.9311.00
244_V307_F0.9311.00
637_S670_L0.9281.00
282_P423_V0.9281.00
240_K270_A0.9261.00
541_D590_R0.9261.00
249_E362_Q0.9251.00
156_L163_H0.9211.00
648_S652_K0.9201.00
466_L499_W0.9181.00
263_P440_S0.9181.00
270_A274_G0.9171.00
262_L309_S0.9161.00
421_L519_V0.9151.00
358_A362_Q0.9101.00
497_Q501_D0.9101.00
675_R681_E0.9091.00
451_V459_L0.9061.00
445_R472_F0.9051.00
694_M702_P0.9041.00
411_S435_V0.9021.00
184_I189_L0.9021.00
619_I624_V0.8991.00
212_S215_Y0.8981.00
193_M196_A0.8981.00
188_M191_Q0.8941.00
230_T267_I0.8941.00
421_L487_G0.8931.00
410_M450_L0.8921.00
166_P169_Q0.8921.00
491_L496_K0.8891.00
583_N586_G0.8891.00
296_S299_T0.8881.00
557_Q581_A0.8861.00
630_E658_L0.8831.00
543_R559_K0.8831.00
259_G285_M0.8821.00
261_M294_L0.8821.00
289_A294_L0.8801.00
288_T440_S0.8771.00
262_L271_V0.8771.00
687_D690_Y0.8741.00
156_L159_Q0.8741.00
164_I168_T0.8731.00
371_L514_T0.8721.00
253_V278_R0.8691.00
599_V609_I0.8691.00
516_C563_I0.8681.00
188_M193_M0.8661.00
545_L592_W0.8661.00
210_L430_L0.8661.00
396_Q538_P0.8631.00
249_E359_Q0.8621.00
171_A177_R0.8611.00
206_L276_I0.8581.00
521_S533_V0.8571.00
483_Y506_R0.8561.00
393_N517_A0.8551.00
190_H194_M0.8531.00
292_K295_T0.8511.00
410_M456_C0.8501.00
289_A698_G0.8481.00
152_V156_L0.8481.00
246_R353_L0.8471.00
148_L152_V0.8471.00
224_V436_F0.8471.00
215_Y357_L0.8461.00
532_T606_F0.8451.00
246_R249_E0.8441.00
242_L357_L0.8441.00
263_P312_F0.8381.00
549_G557_Q0.8361.00
172_M175_A0.8361.00
241_T274_G0.8351.00
166_P182_R0.8341.00
353_L358_A0.8321.00
146_S149_K0.8311.00
217_F235_R0.8311.00
396_Q400_I0.8301.00
496_K507_I0.8291.00
156_L160_I0.8291.00
424_G510_G0.8281.00
632_L635_G0.8271.00
447_V465_F0.8271.00
259_G298_I0.8271.00
237_L270_A0.8261.00
601_F607_V0.8221.00
302_E569_R0.8211.00
637_S669_K0.8211.00
162_L165_L0.8201.00
403_F407_D0.8201.00
393_N424_G0.8201.00
521_S607_V0.8181.00
205_T387_H0.8161.00
466_L484_V0.8161.00
523_N526_M0.8141.00
420_G513_V0.8141.00
390_I518_P0.8131.00
632_L636_V0.8111.00
239_T243_F0.8091.00
645_A656_L0.8081.00
536_I542_A0.8081.00
436_F454_R0.8051.00
209_S430_L0.8021.00
508_L522_I0.8011.00
459_L481_L0.8001.00
211_L357_L0.8001.00
261_M287_Y0.7991.00
600_R610_Q0.7991.00
461_G466_L0.7981.00
170_V177_R0.7961.00
630_E704_F0.7931.00
260_L275_A0.7931.00
408_R457_T0.7931.00
355_P358_A0.7911.00
660_T667_R0.7901.00
204_E209_S0.7881.00
185_A188_M0.7881.00
283_A303_I0.7881.00
439_P446_I0.7851.00
237_L273_F0.7851.00
413_L424_G0.7851.00
198_M399_T0.7821.00
147_R160_I0.7811.00
475_P478_F0.7801.00
400_I524_V0.7781.00
331_V334_E0.7771.00
252_S280_R0.7771.00
424_G519_V0.7721.00
157_F161_T0.7721.00
304_K329_R0.7721.00
246_R357_L0.7681.00
428_P435_V0.7671.00
308_T332_Y0.7631.00
292_K379_H0.7611.00
390_I423_V0.7601.00
249_E361_K0.7601.00
258_I280_R0.7571.00
499_W503_F0.7561.00
520_V542_A0.7511.00
305_T329_R0.7511.00
463_S495_T0.7481.00
496_K525_P0.7481.00
262_L308_T0.7471.00
403_F458_V0.7471.00
336_L339_D0.7461.00
397_I510_G0.7461.00
353_L357_L0.7451.00
175_A179_R0.7441.00
183_K187_E0.7431.00
190_H193_M0.7391.00
266_G270_A0.7381.00
163_H167_P0.7361.00
510_G522_I0.7331.00
249_E358_A0.7331.00
649_D652_K0.7321.00
558_L595_T0.7291.00
198_M539_G0.7291.00
261_M316_G0.7291.00
642_H694_M0.7281.00
403_F427_T0.7271.00
639_D669_K0.7251.00
396_Q537_L0.7231.00
372_F382_G0.7231.00
253_V305_T0.7231.00
649_D654_E0.7201.00
284_M371_L0.7201.00
393_N397_I0.7191.00
175_A178_A0.7171.00
657_V687_D0.7151.00
667_R671_Q0.7131.00
460_F465_F0.7121.00
689_R710_W0.7121.00
220_G406_N0.7121.00
167_P170_V0.7081.00
544_L601_F0.7061.00
438_Y447_V0.7061.00
452_Y477_D0.7041.00
229_F453_D0.7031.00
451_V469_Y0.7001.00
272_I415_L0.7001.00
598_I610_Q0.7001.00
185_A193_M0.6991.00
370_I384_V0.6991.00
149_K156_L0.6991.00
530_P608_Q0.6981.00
451_V480_R0.6981.00
542_A607_V0.6941.00
244_V247_I0.6931.00
259_G306_I0.6931.00
259_G301_A0.6931.00
159_Q603_E0.6931.00
393_N520_V0.6921.00
634_L658_L0.6901.00
557_Q592_W0.6901.00
269_A429_L0.6891.00
191_Q194_M0.6881.00
422_T425_L0.6881.00
162_L166_P0.6881.00
169_Q172_M0.6871.00
159_Q162_L0.6871.00
160_I167_P0.6861.00
205_T362_Q0.6861.00
642_H693_Q0.6850.99
575_V578_V0.6850.99
236_K239_T0.6840.99
289_A682_L0.6830.99
242_L358_A0.6830.99
232_D237_L0.6830.99
599_V607_V0.6820.99
409_F428_P0.6820.99
438_Y442_L0.6810.99
582_E589_E0.6800.99
467_G498_L0.6800.99
620_A681_E0.6800.99
200_V561_P0.6800.99
152_V160_I0.6770.99
243_F355_P0.6770.99
220_G434_E0.6760.99
643_A674_A0.6750.99
385_H389_S0.6750.99
145_F160_I0.6740.99
221_K225_E0.6730.99
312_F315_K0.6720.99
574_G578_V0.6710.99
412_A465_F0.6700.99
243_F247_I0.6690.99
170_V174_D0.6680.99
397_I427_T0.6670.99
517_A520_V0.6660.99
167_P171_A0.6660.99
487_G510_G0.6660.99
434_E454_R0.6640.99
582_E591_G0.6640.99
643_A658_L0.6610.99
243_F246_R0.6610.99
599_V610_Q0.6610.99
498_L501_D0.6600.99
246_R355_P0.6600.99
664_E690_Y0.6590.99
669_K673_Y0.6590.99
281_M370_I0.6580.99
616_F625_S0.6580.99
184_I188_M0.6580.99
535_R601_F0.6580.99
207_Y211_L0.6550.99
209_S213_A0.6520.99
513_V516_C0.6520.99
495_T498_L0.6520.99
649_D653_G0.6510.99
181_R187_E0.6510.99
409_F458_V0.6490.99
364_P388_K0.6490.99
296_S572_K0.6480.99
284_M514_T0.6480.99
384_V565_N0.6460.99
300_A569_R0.6460.99
421_L518_P0.6440.99
368_A390_I0.6440.99
433_A457_T0.6440.99
684_V688_I0.6440.99
639_D663_N0.6430.99
249_E360_V0.6420.99
185_A190_H0.6410.99
666_T690_Y0.6410.99
211_L242_L0.6390.99
629_V656_L0.6380.99
410_M447_V0.6380.99
393_N510_G0.6360.99
543_R592_W0.6350.99
675_R684_V0.6340.99
313_L330_W0.6310.99
412_A519_V0.6300.99
572_K578_V0.6290.99
163_H166_P0.6290.99
265_A437_L0.6290.99
192_I195_E0.6280.99
286_N289_A0.6270.99
408_R455_S0.6270.99
297_A382_G0.6260.99
186_G191_Q0.6250.99
362_Q387_H0.6250.99
406_N457_T0.6250.99
486_A510_G0.6250.99
231_P454_R0.6250.99
557_Q579_P0.6230.99
211_L215_Y0.6220.99
496_K500_Q0.6210.99
401_A485_V0.6210.99
238_L352_L0.6190.99
313_L316_G0.6190.99
219_A233_S0.6180.99
619_I622_E0.6180.99
261_M306_I0.6170.99
397_I460_F0.6170.99
637_S674_A0.6170.99
642_H661_T0.6170.99
468_H471_R0.6160.99
409_F433_A0.6140.99
331_V335_D0.6140.99
149_K154_R0.6130.99
520_V562_N0.6120.99
257_R280_R0.6120.99
428_P431_T0.6110.99
411_S424_G0.6110.99
463_S466_L0.6100.99
421_L424_G0.6090.99
523_N531_G0.6090.99
194_M197_R0.6080.99
186_G193_M0.6080.99
451_V456_C0.6040.99
261_M285_M0.6040.99
150_G160_I0.6030.99
169_Q173_P0.6030.99
413_L461_G0.6010.99
411_S422_T0.6010.99
412_A438_Y0.6000.99
655_A686_R0.5980.99
171_A175_A0.5980.99
185_A194_M0.5980.99
189_L194_M0.5970.99
662_D666_T0.5960.99
257_R303_I0.5960.99
642_H696_L0.5950.99
487_G517_A0.5950.99
636_V673_Y0.5940.99
257_R569_R0.5930.99
189_L192_I0.5930.99
257_R367_E0.5920.99
236_K240_K0.5910.99
196_A200_V0.5910.99
263_P288_T0.5900.99
242_L249_E0.5900.99
338_A341_T0.5890.98
249_E278_R0.5890.98
409_F424_G0.5880.98
660_T665_L0.5870.98
584_V592_W0.5870.98
192_I196_A0.5860.98
629_V683_A0.5860.98
667_R690_Y0.5850.98
583_N589_E0.5850.98
232_D240_K0.5820.98
181_R193_M0.5810.98
646_I708_K0.5810.98
470_A498_L0.5810.98
513_V520_V0.5810.98
674_A684_V0.5810.98
470_A499_W0.5800.98
665_L670_L0.5800.98
511_Y533_V0.5800.98
397_I519_V0.5800.98
397_I485_V0.5790.98
211_L214_M0.5790.98
452_Y476_Y0.5790.98
306_I330_W0.5780.98
423_V426_F0.5780.98
256_E305_T0.5780.98
261_M312_F0.5780.98
665_L669_K0.5770.98
223_C232_D0.5770.98
559_K590_R0.5770.98
158_P161_T0.5770.98
513_V517_A0.5760.98
400_I538_P0.5750.98
626_L683_A0.5750.98
359_Q362_Q0.5750.98
255_G280_R0.5740.98
215_Y238_L0.5740.98
335_D339_D0.5730.98
393_N465_F0.5730.98
208_E361_K0.5720.98
237_L241_T0.5710.98
145_F164_I0.5710.98
659_F689_R0.5710.98
272_I426_F0.5700.98
460_F516_C0.5700.98
384_V566_G0.5700.98
418_S699_S0.5700.98
427_T519_V0.5690.98
451_V455_S0.5670.98
224_V408_R0.5660.98
306_I328_V0.5650.98
460_F520_V0.5650.98
222_K234_Y0.5640.98
163_H552_E0.5630.98
146_S151_L0.5620.98
196_A539_G0.5620.98
148_L153_K0.5600.98
648_S709_S0.5590.98
630_E642_H0.5580.98
394_V426_F0.5580.98
419_F422_T0.5550.98
484_V505_L0.5550.98
462_T519_V0.5550.98
248_L252_S0.5540.98
392_A540_M0.5530.98
487_G520_V0.5530.98
559_K583_N0.5520.98
449_E452_Y0.5520.98
585_R592_W0.5520.98
555_R598_I0.5520.98
189_L196_A0.5520.98
672_Q675_R0.5520.98
463_S486_A0.5510.98
205_T391_L0.5510.98
400_I535_R0.5510.98
159_Q550_I0.5510.98
424_G465_F0.5500.98
397_I537_L0.5490.98
269_A437_L0.5490.98
442_L450_L0.5480.98
500_Q526_M0.5460.98
294_L315_K0.5460.98
481_L484_V0.5440.97
225_E439_P0.5440.97
494_S498_L0.5440.97
337_K341_T0.5420.97
460_F491_L0.5420.97
461_G469_Y0.5420.97
557_Q613_A0.5410.97
617_A647_K0.5410.97
186_G196_A0.5410.97
626_L656_L0.5400.97
155_R603_E0.5400.97
415_L425_L0.5400.97
513_V533_V0.5390.97
383_V514_T0.5390.97
516_C519_V0.5390.97
271_V333_L0.5380.97
197_R541_D0.5370.97
447_V451_V0.5370.97
198_M538_P0.5360.97
665_L690_Y0.5350.97
148_L160_I0.5320.97
649_D655_A0.5310.97
401_A510_G0.5310.97
335_D340_V0.5310.97
213_A218_G0.5310.97
399_T402_D0.5300.97
370_I382_G0.5290.97
376_S627_E0.5290.97
395_E398_K0.5290.97
187_E190_H0.5270.97
579_P613_A0.5270.97
275_A280_R0.5270.97
147_R154_R0.5270.97
462_T510_G0.5260.97
203_R209_S0.5260.97
182_R188_M0.5260.97
544_L556_L0.5260.97
213_A432_G0.5250.97
229_F454_R0.5230.97
268_S272_I0.5220.97
203_R388_K0.5220.97
411_S460_F0.5220.97
487_G513_V0.5210.97
659_F711_V0.5210.97
182_R190_H0.5210.97
412_A424_G0.5210.97
181_R194_M0.5200.97
452_Y479_Y0.5200.97
639_D673_Y0.5200.97
496_K499_W0.5190.97
393_N426_F0.5190.97
285_M298_I0.5180.97
659_F691_L0.5180.97
184_I193_M0.5180.97
498_L502_K0.5160.97
541_D586_G0.5160.97
615_R626_L0.5140.96
459_L484_V0.5140.96
494_S497_Q0.5130.96
202_P561_P0.5130.96
214_M218_G0.5130.96
544_L554_G0.5120.96
638_P673_Y0.5100.96
543_R601_F0.5090.96
393_N421_L0.5080.96
668_D672_Q0.5080.96
208_E212_S0.5070.96
262_L307_F0.5070.96
191_Q195_E0.5070.96
398_K402_D0.5050.96
155_R158_P0.5050.96
521_S558_L0.5030.96
409_F460_F0.5020.96
445_R449_E0.5020.96
499_W505_L0.5010.96
427_T460_F0.5000.96
396_Q510_G0.5000.96
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2vsqA 1 0.943 100 0.414 Contact Map
3tsyA 2 0.5772 100 0.446 Contact Map
4dg8A 1 0.6704 100 0.448 Contact Map
4iz6A 2 0.7232 100 0.461 Contact Map
3ni2A 1 0.7038 100 0.47 Contact Map
3g7sA 2 0.6495 100 0.47 Contact Map
1amuA 1 0.6898 100 0.472 Contact Map
1mdbA 1 0.7204 100 0.477 Contact Map
3etcA 2 0.7038 100 0.478 Contact Map
4d4iA 1 0.6356 100 0.478 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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