MFD - ECOLI - GREMLIN Contacts

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MFD - Transcription-repair-coupling factor

UniProt:	P30958	Sequences: MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHAGPVVLIAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDSFSPHQDIISSRLSTLYQLPTMQRGVLIVPVNTLMQRVCPHSFLHGHALVMKKGQRLSRDALRTQLDSAGYRHVDQVMEHGEYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEAINLLPAHEFPTDKAAIELFRSQWRDTFEVKRDPEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYFPANTLLVNTGDLETSAERFQADTLARFENRGVDPMRPLLPPQSLWLRVDELFSELKNWPRVQLKTEHLPTKAANANLGFQKLPDLAVQAQQKAPLDALRKFLETFDGPVVFSVESEGRREALGELLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDTVRNLALICESDLLGERVARRRQDSRRTINPDTLIRNLAELHIGQPVVHLEHGVGRYAGMTTLEAGGITGEYLMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEKVRDVAAELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDRLVCGDVGFGKTEVAMRAAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEMISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLGLLIVDEEHRFGVRHKERIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSMVVREAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMNDFHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWLLTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGFSLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRIASAKTENELEEIKVELIDRFGLLPDPARTLLDIARLRQQAQKLGIRKLEGNEKGGVIEFAEKNHVNPAWLIGLLQKQPQHYRLDGPTRLKFIQDLSERKTRIEWVRQFMRELEENAIA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11619
Length:	1148 (1109)
Sequences:	2691 (1600)
Seq/√Len:	48.0

ECOLI - MFD
BACSU - MFD

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
829_L	838_I	8.741	1.00
584_K	648_N	7.465	1.00
130_M	189_I	6.517	1.00
698_E	703_K	6.436	1.00
646_V	706_I	6.117	1.00
856_D	861_R	5.604	1.00
712_K	717_D	5.589	1.00
689_A	693_T	5.065	1.00
182_L	189_I	4.912	1.00
814_Y	886_E	4.905	1.00
700_A	719_K	4.905	1.00
650_K	722_D	4.758	1.00
1012_L	1057_A	4.741	1.00
726_L	742_I	4.678	1.00
616_M	645_A	4.640	1.00
131_K	208_A	4.452	1.00
669_F	708_I	4.450	1.00
699_V	707_L	4.403	1.00
169_L	184_F	4.398	1.00
666_Y	670_R	4.391	1.00
681_E	695_I	4.234	1.00
697_A	701_E	4.214	1.00
696_L	718_V	4.183	1.00
694_Q	698_E	4.146	1.00
698_E	707_L	4.063	1.00
681_E	704_I	4.021	1.00
839_A	862_F	3.737	1.00
388_S	428_G	3.647	1.00
646_V	678_V	3.606	1.00
654_V	669_F	3.562	1.00
363_V	373_A	3.538	1.00
45_I	113_L	3.528	1.00
825_A	886_E	3.515	1.00
690_K	694_Q	3.433	1.00
1017_I	1026_F	3.394	1.00
43_V	108_V	3.393	1.00
570_D	574_Q	3.318	1.00
579_E	619_P	3.307	1.00
693_T	697_A	3.296	1.00
120_H	270_P	3.276	1.00
819_V	844_Q	3.274	1.00
494_A	512_T	3.264	1.00
31_V	283_V	3.202	1.00
802_I	833_V	3.184	1.00
642_A	727_I	3.165	1.00
612_V	626_V	3.142	1.00
653_A	713_L	3.122	1.00
679_R	698_E	2.996	1.00
131_K	134_Q	2.996	1.00
180_Y	206_V	2.988	1.00
56_H	107_I	2.986	1.00
52_A	107_I	2.981	1.00
136_L	184_F	2.965	1.00
497_T	510_M	2.952	1.00
146_D	162_Y	2.925	1.00
68_M	94_T	2.905	1.00
141_L	169_L	2.848	1.00
803_L	835_E	2.841	1.00
826_A	866_V	2.837	1.00
698_E	704_I	2.829	1.00
680_I	706_I	2.827	1.00
434_F	443_L	2.811	1.00
512_T	516_D	2.793	1.00
59_I	107_I	2.764	1.00
164_T	169_L	2.729	1.00
284_N	288_L	2.701	1.00
607_Q	611_A	2.698	1.00
491_G	511_L	2.689	1.00
656_V	662_A	2.687	1.00
43_V	106_L	2.663	1.00
395_R	425_L	2.654	1.00
795_S	828_R	2.629	1.00
613_L	644_L	2.629	1.00
1070_A	1078_L	2.544	1.00
690_K	693_T	2.540	1.00
692_Q	712_K	2.528	1.00
234_T	319_S	2.522	1.00
44_L	55_L	2.488	1.00
43_V	282_L	2.481	1.00
407_I	423_R	2.478	1.00
561_V	970_I	2.467	1.00
138_R	169_L	2.463	1.00
812_V	864_V	2.455	1.00
814_Y	825_A	2.439	1.00
377_F	442_A	2.423	1.00
793_Y	798_V	2.412	1.00
688_S	691_E	2.404	1.00
183_D	193_R	2.395	1.00
802_I	864_V	2.390	1.00
59_I	105_V	2.387	1.00
562_R	737_R	2.387	1.00
119_P	265_F	2.384	1.00
1043_K	1058_R	2.384	1.00
799_R	803_L	2.358	1.00
108_V	272_L	2.346	1.00
695_I	704_I	2.335	1.00
129_V	208_A	2.311	1.00
137_S	140_A	2.305	1.00
500_E	505_T	2.304	1.00
816_Y	886_E	2.299	1.00
581_F	584_K	2.263	1.00
732_H	894_A	2.254	1.00
852_R	856_D	2.241	1.00
48_D	51_N	2.230	1.00
271_P	274_S	2.221	1.00
1035_T	1038_E	2.206	1.00
142_R	152_H	2.204	1.00
838_I	864_V	2.199	1.00
697_A	700_A	2.166	1.00
581_F	650_K	2.163	1.00
498_T	505_T	2.154	1.00
383_G	440_N	2.149	1.00
137_S	184_F	2.138	1.00
1029_R	1045_E	2.131	1.00
806_I	836_A	2.129	1.00
642_A	652_V	2.123	1.00
793_Y	814_Y	2.123	1.00
581_F	648_N	2.122	1.00
52_A	69_N	2.118	1.00
694_Q	697_A	2.109	1.00
712_K	715_Q	2.103	1.00
234_T	263_L	2.095	1.00
601_T	606_A	2.079	1.00
56_H	69_N	2.072	1.00
885_I	914_L	2.071	1.00
698_E	701_E	2.051	1.00
1043_K	1061_L	2.039	1.00
683_I	692_Q	2.038	1.00
813_Y	877_I	2.021	1.00
1096_N	1099_W	2.021	1.00
543_H	553_A	2.003	0.99
576_A	620_L	2.003	0.99
974_L	978_L	2.003	0.99
151_R	161_E	1.993	0.99
435_V	442_A	1.990	0.99
836_A	864_V	1.974	0.99
741_R	744_A	1.972	0.99
167_A	183_D	1.972	0.99
601_T	609_I	1.967	0.99
323_R	326_E	1.962	0.99
877_I	880_A	1.958	0.99
196_D	199_S	1.955	0.99
178_L	203_L	1.942	0.99
1030_I	1061_L	1.930	0.99
681_E	687_R	1.927	0.99
28_A	55_L	1.924	0.99
830_A	838_I	1.915	0.99
510_M	518_K	1.914	0.99
695_I	707_L	1.906	0.99
716_S	741_R	1.899	0.99
574_Q	747_A	1.893	0.99
883_I	903_V	1.887	0.99
135_R	187_D	1.879	0.99
295_F	299_T	1.877	0.99
566_A	986_L	1.871	0.99
683_I	707_L	1.863	0.99
827_E	831_E	1.859	0.99
387_F	402_L	1.855	0.99
841_G	853_V	1.848	0.99
837_R	863_N	1.844	0.99
120_H	124_H	1.843	0.99
887_R	917_P	1.842	0.99
829_L	833_V	1.838	0.99
838_I	866_V	1.836	0.99
445_C	448_D	1.835	0.99
683_I	696_L	1.834	0.99
583_F	648_N	1.834	0.99
590_Y	613_L	1.829	0.99
609_I	612_V	1.819	0.99
226_L	230_Q	1.815	0.99
639_M	669_F	1.814	0.99
819_V	822_I	1.812	0.99
180_Y	209_I	1.806	0.99
386_V	418_A	1.794	0.99
826_A	840_I	1.790	0.99
70_L	272_L	1.787	0.99
135_R	186_D	1.783	0.99
653_A	720_F	1.780	0.99
670_R	680_I	1.775	0.99
715_Q	978_L	1.770	0.99
1005_E	1079_E	1.765	0.99
164_T	184_F	1.761	0.99
608_A	626_V	1.758	0.99
583_F	650_K	1.756	0.99
825_A	828_R	1.755	0.99
562_R	962_E	1.743	0.99
591_Q	595_D	1.741	0.98
412_I	424_Y	1.735	0.98
110_V	292_A	1.722	0.98
226_L	266_S	1.717	0.98
578_K	748_N	1.716	0.98
31_V	44_L	1.712	0.98
699_V	704_I	1.711	0.98
829_L	864_V	1.709	0.98
221_K	251_G	1.698	0.98
639_M	668_N	1.689	0.98
793_Y	886_E	1.679	0.98
816_Y	821_N	1.679	0.98
45_I	108_V	1.674	0.98
1046_L	1061_L	1.673	0.98
802_I	812_V	1.670	0.98
1036_E	1065_R	1.668	0.98
1127_E	1130_T	1.668	0.98
833_V	836_A	1.668	0.98
707_L	713_L	1.657	0.98
613_L	617_C	1.650	0.98
642_A	706_I	1.648	0.98
106_L	276_F	1.647	0.98
587_R	647_D	1.643	0.98
1043_K	1053_L	1.639	0.98
815_L	871_I	1.639	0.98
383_G	442_A	1.634	0.98
193_R	202_T	1.627	0.98
557_A	970_I	1.624	0.98
129_V	210_N	1.624	0.98
823_Q	830_A	1.620	0.98
815_L	878_P	1.619	0.98
271_P	322_L	1.610	0.97
358_L	435_V	1.609	0.97
114_M	292_A	1.607	0.97
567_E	744_A	1.605	0.97
883_I	914_L	1.603	0.97
515_N	544_K	1.593	0.97
133_G	188_E	1.587	0.97
399_G	425_L	1.587	0.97
678_V	706_I	1.585	0.97
815_L	875_I	1.585	0.97
562_R	985_A	1.581	0.97
822_I	826_A	1.569	0.97
490_V	543_H	1.567	0.97
695_I	698_E	1.564	0.97
562_R	961_E	1.563	0.97
34_I	283_V	1.550	0.97
696_L	712_K	1.534	0.97
678_V	745_M	1.532	0.97
167_A	186_D	1.531	0.97
829_L	866_V	1.531	0.97
883_I	912_A	1.529	0.97
988_A	992_P	1.526	0.96
726_L	746_R	1.518	0.96
32_A	63_T	1.516	0.96
227_F	264_F	1.513	0.96
1062_D	1136_R	1.513	0.96
297_A	301_A	1.511	0.96
666_Y	682_M	1.510	0.96
586_D	613_L	1.506	0.96
142_R	164_T	1.505	0.96
639_M	708_I	1.502	0.96
1026_F	1046_L	1.498	0.96
822_I	840_I	1.497	0.96
589_Q	647_D	1.491	0.96
581_F	616_M	1.490	0.96
654_V	727_I	1.490	0.96
586_D	590_Y	1.487	0.96
171_L	211_L	1.481	0.96
509_L	529_I	1.481	0.96
687_R	691_E	1.472	0.96
1097_P	1101_I	1.468	0.96
277_P	280_T	1.467	0.96
957_E	962_E	1.466	0.96
300_L	304_E	1.463	0.96
108_V	112_T	1.461	0.95
669_F	706_I	1.460	0.95
1062_D	1065_R	1.460	0.95
55_L	107_I	1.459	0.95
801_A	884_I	1.458	0.95
121_S	125_G	1.452	0.95
887_R	890_H	1.450	0.95
826_A	830_A	1.450	0.95
1015_D	1056_P	1.446	0.95
553_A	557_A	1.445	0.95
108_V	113_L	1.443	0.95
1066_L	1078_L	1.440	0.95
799_R	835_E	1.439	0.95
1012_L	1046_L	1.433	0.95
247_Q	252_T	1.430	0.95
184_F	189_I	1.429	0.95
871_I	875_I	1.423	0.95
738_H	950_L	1.421	0.95
1033_A	1042_I	1.416	0.95
180_Y	194_V	1.412	0.95
566_A	570_D	1.410	0.95
815_L	899_L	1.409	0.95
69_N	107_I	1.399	0.94
557_A	561_V	1.398	0.94
68_M	97_Q	1.397	0.94
753_T	776_I	1.396	0.94
132_K	205_E	1.390	0.94
841_G	850_L	1.390	0.94
176_S	194_V	1.382	0.94
366_Q	370_P	1.380	0.94
70_L	95_L	1.380	0.94
1042_I	1046_L	1.380	0.94
839_A	856_D	1.375	0.94
606_A	610_N	1.374	0.94
1102_G	1106_K	1.368	0.94
1030_I	1039_L	1.365	0.94
117_V	272_L	1.358	0.93
981_N	984_D	1.354	0.93
270_P	274_S	1.353	0.93
839_A	853_V	1.353	0.93
823_Q	840_I	1.352	0.93
610_N	614_S	1.351	0.93
611_A	614_S	1.348	0.93
858_H	877_I	1.346	0.93
589_Q	592_L	1.345	0.93
824_K	828_R	1.336	0.93
611_A	626_V	1.332	0.93
28_A	58_E	1.323	0.92
378_L	385_V	1.322	0.92
590_Y	594_C	1.318	0.92
46_A	109_P	1.315	0.92
583_F	750_D	1.312	0.92
232_R	249_S	1.312	0.92
173_P	176_S	1.302	0.92
119_P	275_Y	1.301	0.92
219_T	224_I	1.284	0.91
22_L	30_L	1.283	0.91
406_K	987_K	1.274	0.91
1039_L	1068_Q	1.274	0.91
687_R	692_Q	1.271	0.91
392_E	396_E	1.271	0.91
228_R	245_Y	1.270	0.91
833_V	864_V	1.265	0.91
291_S	295_F	1.265	0.91
682_M	707_L	1.262	0.90
867_C	873_T	1.262	0.90
113_L	273_F	1.261	0.90
42_V	283_V	1.261	0.90
176_S	180_Y	1.260	0.90
826_A	838_I	1.260	0.90
224_I	251_G	1.257	0.90
375_R	379_E	1.256	0.90
47_P	51_N	1.248	0.90
726_L	749_V	1.243	0.90
626_V	637_V	1.238	0.90
681_E	691_E	1.235	0.90
564_V	961_E	1.224	0.89
31_V	105_V	1.219	0.89
56_H	67_V	1.218	0.89
361_L	370_P	1.216	0.89
544_K	547_G	1.213	0.89
136_L	141_L	1.209	0.88
140_A	144_Q	1.208	0.88
41_P	280_T	1.208	0.88
889_D	920_K	1.207	0.88
106_L	272_L	1.205	0.88
1055_D	1058_R	1.205	0.88
617_C	644_L	1.198	0.88
377_F	444_I	1.198	0.88
816_Y	825_A	1.197	0.88
282_L	331_L	1.197	0.88
726_L	751_I	1.196	0.88
1034_K	1038_E	1.195	0.88
132_K	207_E	1.193	0.88
932_A	945_L	1.192	0.88
950_L	955_A	1.189	0.88
46_A	108_V	1.184	0.87
376_K	380_T	1.184	0.87
654_V	708_I	1.180	0.87
681_E	698_E	1.180	0.87
856_D	862_F	1.180	0.87
22_L	26_A	1.178	0.87
400_E	404_R	1.178	0.87
766_A	770_M	1.176	0.87
291_S	299_T	1.175	0.87
614_S	618_Q	1.172	0.87
1036_E	1040_E	1.172	0.87
141_L	184_F	1.170	0.87
691_E	694_Q	1.169	0.87
795_S	831_E	1.163	0.86
673_F	706_I	1.159	0.86
680_I	708_I	1.156	0.86
130_M	182_L	1.148	0.86
46_A	55_L	1.148	0.86
482_P	492_R	1.142	0.85
652_V	727_I	1.142	0.85
1033_A	1038_E	1.142	0.85
776_I	873_T	1.138	0.85
29_T	436_D	1.134	0.85
677_P	680_I	1.133	0.85
1013_P	1057_A	1.132	0.85
40_G	279_N	1.131	0.85
727_I	1067_R	1.130	0.85
45_I	273_F	1.130	0.85
798_V	829_L	1.129	0.85
1030_I	1064_A	1.128	0.85
479_I	493_Y	1.126	0.85
377_F	383_G	1.116	0.84
185_F	190_D	1.116	0.84
821_N	825_A	1.116	0.84
692_Q	696_L	1.114	0.84
25_A	58_E	1.113	0.84
180_Y	192_L	1.113	0.84
157_M	161_E	1.110	0.84
141_L	171_L	1.104	0.83
574_Q	578_K	1.101	0.83
1017_I	1046_L	1.098	0.83
231_W	234_T	1.097	0.83
159_H	172_F	1.095	0.83
135_R	188_E	1.092	0.83
679_R	703_K	1.091	0.83
703_K	707_L	1.090	0.83
879_T	908_H	1.089	0.83
94_T	98_L	1.087	0.82
178_L	194_V	1.085	0.82
138_R	142_R	1.085	0.82
25_A	62_F	1.084	0.82
31_V	55_L	1.084	0.82
487_E	525_S	1.083	0.82
854_M	875_I	1.082	0.82
138_R	184_F	1.079	0.82
645_A	652_V	1.076	0.82
279_N	286_G	1.075	0.82
64_D	67_V	1.074	0.82
41_P	277_P	1.073	0.82
1039_L	1061_L	1.072	0.82
91_R	216_E	1.071	0.82
194_V	204_E	1.071	0.82
136_L	169_L	1.070	0.81
370_P	449_L	1.068	0.81
1075_I	1078_L	1.067	0.81
798_V	915_L	1.059	0.81
776_I	844_Q	1.058	0.81
1040_E	1043_K	1.054	0.80
647_D	678_V	1.054	0.80
551_S	555_Q	1.053	0.80
496_M	1023_R	1.049	0.80
884_I	915_L	1.049	0.80
766_A	772_D	1.047	0.80
385_V	442_A	1.045	0.80
486_L	977_E	1.044	0.80
1047_I	1052_L	1.042	0.80
63_T	105_V	1.040	0.80
73_W	115_Q	1.040	0.80
35_A	105_V	1.034	0.79
168_L	744_A	1.031	0.79
511_L	749_V	1.028	0.79
299_T	302_R	1.026	0.79
737_R	741_R	1.023	0.78
608_A	611_A	1.023	0.78
552_R	556_K	1.019	0.78
117_V	275_Y	1.017	0.78
561_V	770_M	1.017	0.78
683_I	718_V	1.017	0.78
577_A	983_V	1.017	0.78
414_R	417_E	1.014	0.78
1030_I	1042_I	1.013	0.78
1076_R	1118_R	1.011	0.78
246_Q	833_V	1.010	0.78
394_R	450_L	1.008	0.77
386_V	426_M	1.006	0.77
128_L	141_L	1.004	0.77
1039_L	1065_R	1.000	0.77
1042_I	1061_L	0.999	0.77
202_T	1006_L	0.997	0.77
43_V	276_F	0.996	0.77
792_E	934_A	0.995	0.77
1002_T	1071_Q	0.995	0.77
94_T	106_L	0.992	0.76
73_W	77_P	0.992	0.76
663_Q	682_M	0.990	0.76
877_I	891_F	0.989	0.76
274_S	330_E	0.988	0.76
689_A	692_Q	0.988	0.76
793_Y	828_R	0.987	0.76
244_I	260_W	0.985	0.76
107_I	868_T	0.985	0.76
179_P	195_F	0.985	0.76
586_D	644_L	0.984	0.76
287_D	290_T	0.984	0.76
1037_N	1040_E	0.982	0.76
70_L	112_T	0.982	0.76
279_N	284_N	0.980	0.75
190_D	1047_I	0.978	0.75
572_Y	750_D	0.978	0.75
58_E	431_E	0.978	0.75
139_D	142_R	0.977	0.75
616_M	750_D	0.972	0.75
583_F	616_M	0.971	0.75
418_A	1061_L	0.971	0.75
627_C	854_M	0.971	0.75
980_E	984_D	0.970	0.75
890_H	926_A	0.970	0.75
246_Q	250_K	0.969	0.75
681_E	707_L	0.964	0.74
840_I	866_V	0.964	0.74
1125_L	1134_W	0.964	0.74
291_S	297_A	0.962	0.74
33_E	36_E	0.960	0.74
588_E	592_L	0.959	0.74
570_D	985_A	0.958	0.74
185_F	673_F	0.957	0.74
1093_N	1096_N	0.956	0.74
587_R	590_Y	0.955	0.73
594_C	613_L	0.954	0.73
704_I	707_L	0.954	0.73
157_M	632_F	0.949	0.73
428_G	700_A	0.948	0.73
1069_Q	1072_K	0.945	0.73
162_Y	786_V	0.945	0.73
317_P	321_W	0.945	0.73
586_D	765_M	0.943	0.73
784_L	909_Q	0.943	0.73
639_M	747_A	0.939	0.72
900_R	1049_R	0.939	0.72
860_Q	879_T	0.936	0.72
667_D	670_R	0.936	0.72
803_L	829_L	0.933	0.72
388_S	426_M	0.933	0.72
1030_I	1033_A	0.931	0.72
151_R	192_L	0.931	0.72
295_F	302_R	0.930	0.71
274_S	1046_L	0.928	0.71
1004_V	1066_L	0.925	0.71
506_G	524_S	0.925	0.71
530_S	1028_K	0.925	0.71
579_E	885_I	0.924	0.71
294_R	298_D	0.924	0.71
791_R	797_V	0.922	0.71
140_A	143_T	0.922	0.71
136_L	189_I	0.922	0.71
41_P	279_N	0.921	0.71
926_A	952_I	0.921	0.71
90_S	93_S	0.919	0.71
1133_E	1137_Q	0.919	0.71
563_D	566_A	0.919	0.71
743_K	751_I	0.918	0.70
292_A	324_V	0.916	0.70
567_E	570_D	0.915	0.70
99_P	556_K	0.915	0.70
193_R	851_E	0.914	0.70
604_D	778_T	0.913	0.70
885_I	933_I	0.911	0.70
826_A	829_L	0.909	0.70
283_V	337_V	0.909	0.70
1053_L	1057_A	0.908	0.70
1026_F	1050_F	0.908	0.70
491_G	749_V	0.906	0.69
172_F	179_P	0.904	0.69
281_L	284_N	0.902	0.69
1029_R	1042_I	0.900	0.69
593_F	639_M	0.900	0.69
1041_E	1044_V	0.900	0.69
99_P	124_H	0.898	0.69
564_V	957_E	0.897	0.69
116_R	326_E	0.896	0.69
639_M	680_I	0.895	0.69
662_A	682_M	0.895	0.69
786_V	1132_I	0.895	0.69
221_K	224_I	0.895	0.69
371_L	375_R	0.895	0.69
632_F	779_P	0.893	0.68
800_E	804_R	0.891	0.68
836_A	863_N	0.891	0.68
374_L	385_V	0.890	0.68
373_A	377_F	0.890	0.68
19_L	30_L	0.889	0.68
450_L	871_I	0.889	0.68
319_S	326_E	0.889	0.68
779_P	1067_R	0.888	0.68
200_Q	1049_R	0.888	0.68
590_Y	644_L	0.887	0.68
78_Y	951_E	0.886	0.68
29_T	62_F	0.884	0.68
425_L	618_Q	0.884	0.68
580_G	750_D	0.884	0.68
728_V	841_G	0.884	0.68
31_V	42_V	0.883	0.67
310_P	314_L	0.883	0.67
778_T	939_L	0.881	0.67
511_L	529_I	0.881	0.67
436_D	439_R	0.881	0.67
243_H	247_Q	0.880	0.67
766_A	844_Q	0.880	0.67
606_A	981_N	0.879	0.67
698_E	708_I	0.879	0.67
580_G	616_M	0.876	0.67
222_A	225_E	0.875	0.67
556_K	968_E	0.875	0.67
363_V	370_P	0.874	0.67
643_F	647_D	0.873	0.67
1043_K	1065_R	0.873	0.67
596_S	675_N	0.872	0.67
1007_R	1080_G	0.871	0.66
370_P	444_I	0.871	0.66
206_V	334_W	0.871	0.66
482_P	540_A	0.870	0.66
1087_I	1135_V	0.870	0.66
764_N	976_M	0.869	0.66
70_L	117_V	0.868	0.66
825_A	866_V	0.868	0.66
571_I	773_L	0.868	0.66
493_Y	675_N	0.867	0.66
621_A	776_I	0.867	0.66
238_K	242_E	0.866	0.66
873_T	878_P	0.865	0.66
44_L	107_I	0.865	0.66
432_H	680_I	0.865	0.66
122_F	265_F	0.865	0.66
99_P	120_H	0.865	0.66
806_I	864_V	0.862	0.66
779_P	958_L	0.861	0.66
349_A	352_N	0.860	0.65
728_V	747_A	0.859	0.65
482_P	539_N	0.858	0.65
986_L	1035_T	0.858	0.65
491_G	513_Y	0.858	0.65
95_L	272_L	0.858	0.65
387_F	398_L	0.857	0.65
500_E	503_G	0.856	0.65
583_F	618_Q	0.856	0.65
96_Y	212_L	0.856	0.65
325_D	329_S	0.855	0.65
688_S	798_V	0.855	0.65
562_R	570_D	0.850	0.65
978_L	981_N	0.850	0.65
982_A	985_A	0.850	0.65
773_L	967_M	0.848	0.64
608_A	669_F	0.848	0.64
156_V	195_F	0.847	0.64
121_S	267_E	0.846	0.64
392_E	427_I	0.846	0.64
178_L	197_V	0.846	0.64
434_F	448_D	0.845	0.64
71_A	90_S	0.844	0.64
476_E	561_V	0.844	0.64
670_R	681_E	0.843	0.64
573_A	776_I	0.843	0.64
460_D	523_V	0.843	0.64
483_V	812_V	0.840	0.64
795_S	832_L	0.840	0.64
615_D	624_R	0.839	0.63
840_I	853_V	0.839	0.63
684_S	813_Y	0.838	0.63
77_P	778_T	0.838	0.63
663_Q	855_N	0.838	0.63
276_F	280_T	0.838	0.63
824_K	827_E	0.838	0.63
521_V	529_I	0.837	0.63
42_V	105_V	0.836	0.63
900_R	1048_D	0.835	0.63
525_S	947_T	0.833	0.63
41_P	106_L	0.833	0.63
1044_V	1052_L	0.833	0.63
221_K	620_L	0.832	0.63
984_D	988_A	0.831	0.63
1030_I	1068_Q	0.830	0.63
814_Y	829_L	0.829	0.63
116_R	269_L	0.829	0.63
468_D	559_E	0.827	0.62
716_S	719_K	0.827	0.62
530_S	897_H	0.827	0.62
708_I	785_A	0.826	0.62
688_S	1069_Q	0.826	0.62
244_I	259_Y	0.826	0.62
443_L	827_E	0.825	0.62
1065_R	1069_Q	0.825	0.62
737_R	744_A	0.825	0.62
786_V	883_I	0.824	0.62
395_R	427_I	0.824	0.62
134_Q	184_F	0.823	0.62
296_Q	300_L	0.823	0.62
897_H	1023_R	0.822	0.62
31_V	107_I	0.821	0.62
594_C	644_L	0.820	0.62
625_L	978_L	0.820	0.62
751_I	897_H	0.819	0.62
228_R	249_S	0.819	0.62
99_P	106_L	0.819	0.62
184_F	649_H	0.819	0.62
196_D	203_L	0.818	0.62
599_F	786_V	0.817	0.61
933_I	945_L	0.817	0.61
586_D	589_Q	0.817	0.61
1026_F	1033_A	0.817	0.61
371_L	407_I	0.816	0.61
119_P	153_V	0.816	0.61
692_Q	923_T	0.816	0.61
587_R	648_N	0.814	0.61
593_F	596_S	0.812	0.61
740_E	751_I	0.810	0.61
654_V	670_R	0.810	0.61
232_R	245_Y	0.809	0.61
793_Y	825_A	0.809	0.61
705_D	721_K	0.809	0.61
586_D	1005_E	0.808	0.61
142_R	162_Y	0.807	0.60
128_L	137_S	0.803	0.60
514_A	972_F	0.801	0.60
699_V	720_F	0.799	0.60
98_L	106_L	0.799	0.60
46_A	52_A	0.799	0.60
269_L	272_L	0.795	0.59
53_L	69_N	0.795	0.59
167_A	191_S	0.795	0.59
786_V	816_Y	0.795	0.59
471_I	742_I	0.793	0.59
375_R	406_K	0.790	0.59
19_L	355_F	0.789	0.59
1011_L	1023_R	0.789	0.59
403_A	408_A	0.789	0.59
395_R	411_R	0.789	0.59
34_I	728_V	0.789	0.59
322_L	326_E	0.788	0.59
143_T	221_K	0.787	0.59
145_L	162_Y	0.787	0.59
274_S	745_M	0.786	0.58
728_V	988_A	0.786	0.58
87_I	264_F	0.786	0.58
394_R	446_E	0.786	0.58
273_F	322_L	0.786	0.58
415_L	1046_L	0.785	0.58
1044_V	1047_I	0.783	0.58
491_G	583_F	0.783	0.58
697_A	719_K	0.781	0.58
616_M	650_K	0.780	0.58
800_E	911_Y	0.779	0.58
626_V	773_L	0.778	0.58
742_I	749_V	0.776	0.57
660_L	894_A	0.771	0.57
384_P	424_Y	0.771	0.57
822_I	866_V	0.771	0.57
219_T	253_L	0.770	0.57
649_H	915_L	0.769	0.57
646_V	669_F	0.769	0.57
399_G	403_A	0.768	0.57
983_V	986_L	0.768	0.57
130_M	211_L	0.767	0.57
732_H	782_R	0.766	0.56
576_A	618_Q	0.765	0.56
167_A	632_F	0.765	0.56
199_S	273_F	0.764	0.56
116_R	271_P	0.764	0.56
39_A	103_R	0.763	0.56
353_L	358_L	0.762	0.56
745_M	890_H	0.762	0.56
686_F	850_L	0.761	0.56
335_P	342_E	0.761	0.56
590_Y	948_H	0.760	0.56
313_P	316_P	0.760	0.56
530_S	738_H	0.759	0.56
73_W	83_P	0.759	0.56
501_A	1008_M	0.759	0.56
143_T	147_S	0.758	0.56
1045_E	1049_R	0.758	0.56
430_A	443_L	0.758	0.56
100_T	871_I	0.757	0.56
43_V	384_P	0.757	0.56
370_P	374_L	0.756	0.55
398_L	449_L	0.756	0.55
642_A	800_E	0.755	0.55
505_T	1009_P	0.754	0.55
586_D	594_C	0.754	0.55
1057_A	1060_L	0.753	0.55
899_L	1044_V	0.753	0.55
130_M	164_T	0.752	0.55
216_E	258_E	0.752	0.55
301_A	304_E	0.751	0.55
813_Y	880_A	0.751	0.55
348_A	352_N	0.751	0.55
280_T	284_N	0.750	0.55
846_R	849_E	0.749	0.55
132_K	164_T	0.748	0.55
879_T	924_T	0.747	0.55
582_A	626_V	0.745	0.54
374_L	377_F	0.744	0.54
1013_P	1054_P	0.743	0.54
376_K	442_A	0.743	0.54
298_D	302_R	0.742	0.54
355_F	358_L	0.741	0.54
139_D	143_T	0.741	0.54
873_T	877_I	0.741	0.54
679_R	701_E	0.740	0.54
115_Q	321_W	0.740	0.54
1064_A	1067_R	0.740	0.54
851_E	855_N	0.740	0.54
853_V	1127_E	0.740	0.54
250_K	728_V	0.739	0.54
143_T	708_I	0.738	0.54
692_Q	717_D	0.738	0.54
28_A	59_I	0.737	0.54
229_S	233_D	0.736	0.53
786_V	1042_I	0.736	0.53
837_R	861_R	0.736	0.53
183_D	186_D	0.732	0.53
293_E	443_L	0.732	0.53
330_E	334_W	0.731	0.53
299_T	321_W	0.731	0.53
666_Y	681_E	0.731	0.53
277_P	708_I	0.729	0.53
222_A	267_E	0.729	0.53
389_V	398_L	0.729	0.53
719_K	722_D	0.727	0.53
612_V	637_V	0.727	0.53
36_E	65_Q	0.726	0.52
152_H	164_T	0.725	0.52
751_I	923_T	0.724	0.52
324_V	327_L	0.723	0.52
449_L	1066_L	0.722	0.52
137_S	766_A	0.722	0.52
220_D	223_A	0.721	0.52
626_V	753_T	0.720	0.52
1134_W	1137_Q	0.720	0.52
815_L	825_A	0.720	0.52
161_E	939_L	0.720	0.52
221_K	225_E	0.720	0.52
90_S	141_L	0.719	0.52
120_H	1042_I	0.719	0.52
493_Y	746_R	0.718	0.52
680_I	722_D	0.718	0.52
564_V	962_E	0.718	0.52
112_T	119_P	0.717	0.52
680_I	698_E	0.717	0.52
143_T	146_D	0.717	0.52
668_N	928_K	0.716	0.51
804_R	920_K	0.715	0.51
558_A	1058_R	0.715	0.51
471_I	1028_K	0.714	0.51
118_C	891_F	0.714	0.51
618_Q	728_V	0.714	0.51
290_T	293_E	0.713	0.51
655_L	750_D	0.713	0.51
645_A	650_K	0.713	0.51
823_Q	827_E	0.713	0.51
1025_S	1029_R	0.713	0.51
728_V	860_Q	0.712	0.51
914_L	964_S	0.711	0.51
972_F	981_N	0.711	0.51
548_D	551_S	0.711	0.51
935_S	948_H	0.711	0.51
696_L	713_L	0.709	0.51
552_R	813_Y	0.709	0.51
69_N	108_V	0.708	0.51
295_F	301_A	0.707	0.51
520_Y	813_Y	0.706	0.50
224_I	249_S	0.706	0.50
828_R	831_E	0.706	0.50
1130_T	1133_E	0.705	0.50
199_S	1086_V	0.705	0.50
492_R	512_T	0.704	0.50
682_M	687_R	0.704	0.50
804_R	911_Y	0.704	0.50
400_E	713_L	0.703	0.50
131_K	206_V	0.703	0.50
1038_E	1041_E	0.702	0.50
806_I	809_G	0.702	0.50
1033_A	1039_L	0.701	0.50
863_N	883_I	0.701	0.50
1078_L	1087_I	0.700	0.50
150_Y	172_F	0.699	0.50
827_E	830_A	0.699	0.50
48_D	110_V	0.699	0.50
841_G	1012_L	0.699	0.50
782_R	1024_L	0.698	0.50
327_L	529_I	0.697	0.50
556_K	744_A	0.696	0.49
534_G	915_L	0.696	0.49
984_D	989_G	0.696	0.49
1107_Q	1110_H	0.696	0.49
445_C	511_L	0.695	0.49
42_V	281_L	0.695	0.49
592_L	595_D	0.693	0.49
194_V	206_V	0.692	0.49
612_V	669_F	0.692	0.49
654_V	706_I	0.692	0.49
932_A	952_I	0.692	0.49
479_I	749_V	0.691	0.49
397_A	939_L	0.691	0.49
162_Y	199_S	0.690	0.49
185_F	690_K	0.690	0.49
1078_L	1135_V	0.689	0.49
662_A	684_S	0.688	0.49
1075_I	1087_I	0.687	0.49
325_D	958_L	0.687	0.49
585_H	694_Q	0.686	0.48
706_I	830_A	0.686	0.48
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510_M	520_Y	0.681	0.48
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292_A	295_F	0.555	0.36
1003_E	1077_K	0.555	0.36
1105_Q	1108_P	0.555	0.36
726_L	748_N	0.555	0.36
450_L	891_F	0.554	0.36
525_S	859_H	0.554	0.36
1125_L	1128_R	0.554	0.36
401_L	625_L	0.554	0.36
172_F	809_G	0.553	0.36
621_A	913_W	0.553	0.36
79_D	776_I	0.552	0.35
130_M	1052_L	0.552	0.35
1017_I	1067_R	0.552	0.35
499_L	502_G	0.551	0.35
61_Q	914_L	0.551	0.35
581_F	750_D	0.551	0.35
1126_S	1130_T	0.551	0.35
190_D	967_M	0.551	0.35
420_D	704_I	0.551	0.35
131_K	188_E	0.551	0.35
25_A	434_F	0.551	0.35
799_R	860_Q	0.551	0.35
190_D	1052_L	0.551	0.35
48_D	911_Y	0.550	0.35
871_I	941_A	0.550	0.35
563_D	873_T	0.550	0.35
573_A	576_A	0.549	0.35
619_P	978_L	0.549	0.35
501_A	824_K	0.549	0.35
632_F	764_N	0.548	0.35
675_N	838_I	0.548	0.35
285_T	599_F	0.548	0.35
168_L	206_V	0.548	0.35
309_D	313_P	0.548	0.35
263_L	273_F	0.548	0.35
674_A	856_D	0.548	0.35
251_G	425_L	0.547	0.35
234_T	316_P	0.547	0.35
69_N	90_S	0.547	0.35
473_N	476_E	0.547	0.35
338_Q	344_L	0.547	0.35
373_A	1024_L	0.547	0.35
830_A	864_V	0.547	0.35
772_D	972_F	0.546	0.35
1133_E	1136_R	0.546	0.35
535_G	1033_A	0.546	0.35
951_E	976_M	0.546	0.35
258_E	262_P	0.546	0.35
815_L	866_V	0.546	0.35
653_A	727_I	0.545	0.35
488_H	501_A	0.545	0.35
118_C	501_A	0.545	0.35
806_I	837_R	0.545	0.35
171_L	182_L	0.545	0.35
626_V	728_V	0.545	0.35
184_F	704_I	0.545	0.35
526_L	775_I	0.545	0.35
866_V	886_E	0.544	0.35
691_E	835_E	0.544	0.35
593_F	673_F	0.544	0.35
24_G	58_E	0.544	0.35
106_L	207_E	0.543	0.35
639_M	654_V	0.543	0.35
263_L	446_E	0.543	0.35
237_V	241_P	0.543	0.35
653_A	709_G	0.543	0.35
766_A	853_V	0.543	0.35
606_A	1063_I	0.543	0.35
820_E	844_Q	0.542	0.35
43_V	221_K	0.542	0.35
726_L	799_R	0.542	0.35
218_P	678_V	0.542	0.35
879_T	933_I	0.542	0.35
662_A	766_A	0.542	0.35
37_R	43_V	0.541	0.34
627_C	793_Y	0.541	0.34
423_R	1085_G	0.541	0.34
65_Q	233_D	0.540	0.34
521_V	551_S	0.540	0.34
867_C	978_L	0.540	0.34
543_H	933_I	0.539	0.34
1111_Y	1123_Q	0.539	0.34
544_K	691_E	0.539	0.34
712_K	755_T	0.539	0.34
430_A	878_P	0.539	0.34
74_E	1065_R	0.539	0.34
171_L	1112_R	0.539	0.34
962_E	1018_P	0.539	0.34
844_Q	848_R	0.539	0.34
626_V	1044_V	0.539	0.34
435_V	444_I	0.538	0.34
507_E	915_L	0.538	0.34
854_M	873_T	0.538	0.34
77_P	81_F	0.538	0.34
429_A	434_F	0.537	0.34
683_I	862_F	0.537	0.34
396_E	579_E	0.537	0.34
690_K	1017_I	0.537	0.34
473_N	530_S	0.537	0.34
700_A	837_R	0.536	0.34
192_L	405_I	0.536	0.34
1121_F	1132_I	0.536	0.34
479_I	745_M	0.536	0.34
322_L	327_L	0.535	0.34
572_Y	686_F	0.535	0.34
323_R	728_V	0.535	0.34
1108_P	1111_Y	0.535	0.34
567_E	851_E	0.535	0.34
674_A	926_A	0.534	0.34
106_L	117_V	0.534	0.34
828_R	885_I	0.534	0.34
1026_F	1029_R	0.534	0.34
141_L	453_R	0.533	0.34
822_I	842_H	0.533	0.34
246_Q	353_L	0.533	0.34
732_H	909_Q	0.533	0.34
536_A	885_I	0.533	0.34
375_R	407_I	0.533	0.34
713_L	928_K	0.533	0.34
962_E	1003_E	0.533	0.34
194_V	1004_V	0.532	0.34
542_L	609_I	0.532	0.34
117_V	398_L	0.532	0.34
315_L	556_K	0.532	0.34
815_L	974_L	0.532	0.34
330_E	333_N	0.532	0.34
92_L	1006_L	0.532	0.34
767_M	786_V	0.531	0.34
314_L	317_P	0.531	0.34
517_A	529_I	0.531	0.34
298_D	766_A	0.531	0.34
399_G	409_P	0.531	0.34
682_M	695_I	0.531	0.34
56_H	983_V	0.531	0.34
833_V	863_N	0.531	0.34
604_D	777_A	0.530	0.33
163_A	269_L	0.530	0.33
260_W	527_H	0.530	0.33
81_F	972_F	0.530	0.33
182_L	1095_V	0.530	0.33
566_A	985_A	0.529	0.33
851_E	857_F	0.529	0.33
534_G	561_V	0.529	0.33
26_A	171_L	0.529	0.33
916_T	919_P	0.529	0.33
644_L	879_T	0.529	0.33
386_V	424_Y	0.529	0.33
511_L	1069_Q	0.528	0.33
19_L	727_I	0.528	0.33
398_L	958_L	0.528	0.33
520_Y	674_A	0.528	0.33
625_L	687_R	0.528	0.33
448_D	969_T	0.528	0.33
70_L	163_A	0.527	0.33
423_R	708_I	0.527	0.33
108_V	1069_Q	0.527	0.33
26_A	981_N	0.527	0.33
177_E	1015_D	0.527	0.33
230_Q	266_S	0.527	0.33
201_R	523_V	0.527	0.33
158_E	161_E	0.527	0.33
106_L	432_H	0.527	0.33
93_S	274_S	0.527	0.33
192_L	219_T	0.526	0.33
282_L	285_T	0.526	0.33
857_F	939_L	0.526	0.33
967_M	986_L	0.526	0.33
482_P	541_P	0.526	0.33
830_A	839_A	0.526	0.33
1131_R	1134_W	0.526	0.33
45_I	991_E	0.526	0.33
613_L	948_H	0.525	0.33
88_I	821_N	0.525	0.33
98_L	1018_P	0.525	0.33
107_I	274_S	0.525	0.33
581_F	645_A	0.525	0.33
855_N	859_H	0.525	0.33
835_E	1073_L	0.524	0.33
660_L	978_L	0.524	0.33
1017_I	1062_D	0.524	0.33
486_L	841_G	0.524	0.33
509_L	518_K	0.524	0.33
180_Y	678_V	0.523	0.33
1132_I	1137_Q	0.523	0.33
192_L	243_H	0.522	0.33
686_F	750_D	0.522	0.33
524_S	1003_E	0.522	0.33
790_V	976_M	0.522	0.33
176_S	206_V	0.522	0.33
817_N	847_E	0.522	0.33
112_T	193_R	0.522	0.33
1008_M	1059_T	0.522	0.33
675_N	679_R	0.522	0.33
754_L	873_T	0.522	0.33
230_Q	234_T	0.521	0.33
508_Y	919_P	0.521	0.33
378_L	422_G	0.521	0.33
502_G	980_E	0.521	0.33
503_G	952_I	0.521	0.33
793_Y	884_I	0.521	0.33
296_Q	299_T	0.521	0.33
444_I	496_M	0.521	0.33
819_V	983_V	0.521	0.33
754_L	947_T	0.521	0.33
529_I	717_D	0.520	0.33
108_V	282_L	0.520	0.33
139_D	164_T	0.520	0.33
546_G	957_E	0.519	0.32
349_A	353_L	0.519	0.32
449_L	556_K	0.519	0.32
491_G	699_V	0.519	0.32
205_E	1052_L	0.519	0.32
663_Q	976_M	0.518	0.32
509_L	837_R	0.518	0.32
265_F	894_A	0.518	0.32
645_A	728_V	0.518	0.32
298_D	625_L	0.518	0.32
1021_N	1025_S	0.518	0.32
908_H	979_L	0.518	0.32
948_H	973_S	0.518	0.32
646_V	987_K	0.517	0.32
701_E	721_K	0.517	0.32
910_A	1075_I	0.517	0.32
789_F	1047_I	0.517	0.32
850_L	1024_L	0.517	0.32
790_V	873_T	0.516	0.32
237_V	394_R	0.516	0.32
497_T	773_L	0.516	0.32
461_S	981_N	0.516	0.32
315_L	319_S	0.515	0.32
580_G	817_N	0.515	0.32
66_M	337_V	0.515	0.32
653_A	723_L	0.515	0.32
1123_Q	1134_W	0.514	0.32
219_T	226_L	0.514	0.32
70_L	94_T	0.514	0.32
663_Q	899_L	0.514	0.32
551_S	574_Q	0.513	0.32
639_M	646_V	0.513	0.32
432_H	1085_G	0.513	0.32
831_E	838_I	0.513	0.32
259_Y	1024_L	0.513	0.32
585_H	617_C	0.513	0.32
219_T	425_L	0.512	0.32
988_A	991_E	0.512	0.32
755_T	894_A	0.512	0.32
153_V	271_P	0.512	0.32
819_V	836_A	0.511	0.32
231_W	245_Y	0.511	0.32
769_G	970_I	0.511	0.32
446_E	509_L	0.510	0.32
288_L	482_P	0.510	0.32
612_V	676_W	0.510	0.32
526_L	917_P	0.510	0.32
1098_A	1102_G	0.510	0.32
198_D	202_T	0.510	0.32
372_D	680_I	0.510	0.32
593_F	777_A	0.510	0.32
151_R	158_E	0.510	0.32
764_N	866_V	0.510	0.32
583_F	653_A	0.509	0.32
131_K	203_L	0.509	0.32
842_H	903_V	0.509	0.32
639_M	928_K	0.509	0.32
938_D	1045_E	0.508	0.31
572_Y	625_L	0.508	0.31
169_L	683_I	0.508	0.31
359_P	608_A	0.508	0.31
677_P	706_I	0.508	0.31
425_L	591_Q	0.508	0.31
1102_G	1105_Q	0.507	0.31
767_M	1132_I	0.507	0.31
243_H	581_F	0.507	0.31
111_N	295_F	0.507	0.31
44_L	285_T	0.507	0.31
172_F	264_F	0.507	0.31
507_E	515_N	0.507	0.31
720_F	1089_F	0.506	0.31
141_L	583_F	0.506	0.31
530_S	964_S	0.506	0.31
74_E	856_D	0.506	0.31
526_L	859_H	0.506	0.31
282_L	425_L	0.506	0.31
85_Q	547_G	0.506	0.31
93_S	210_N	0.506	0.31
353_L	359_P	0.506	0.31
499_L	714_L	0.506	0.31
272_L	416_D	0.505	0.31
755_T	1019_D	0.505	0.31
520_Y	660_L	0.505	0.31
573_A	666_Y	0.505	0.31
582_A	704_I	0.505	0.31
261_Q	269_L	0.505	0.31
932_A	936_L	0.504	0.31
221_K	408_A	0.504	0.31
732_H	754_L	0.504	0.31
704_I	1087_I	0.504	0.31
201_R	705_D	0.504	0.31
185_F	188_E	0.503	0.31
359_P	1041_E	0.503	0.31
74_E	251_G	0.503	0.31
943_F	980_E	0.503	0.31
863_N	950_L	0.503	0.31
1004_V	1063_I	0.503	0.31
190_D	626_V	0.503	0.31
562_R	897_H	0.503	0.31
479_I	496_M	0.503	0.31
474_L	632_F	0.502	0.31
547_G	727_I	0.502	0.31
77_P	986_L	0.502	0.31
209_I	382_D	0.502	0.31
692_Q	695_I	0.502	0.31
306_R	915_L	0.502	0.31
755_T	773_L	0.502	0.31
130_M	766_A	0.502	0.31
221_K	278_A	0.502	0.31
691_E	699_V	0.502	0.31
849_E	899_L	0.501	0.31
925_D	952_I	0.501	0.31
468_D	471_I	0.501	0.31
34_I	1038_E	0.501	0.31
167_A	610_N	0.501	0.31
182_L	512_T	0.501	0.31
687_R	695_I	0.501	0.31
891_F	896_L	0.500	0.31
27_C	285_T	0.500	0.31
167_A	510_M	0.500	0.31
666_Y	814_Y	0.500	0.31

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3hjhA	1	0.3868	100	0.784	Contact Map
1gm5A	1	0.5932	100	0.797	Contact Map
2d7dA	2	0.4913	100	0.821	Contact Map
1c4oA	1	0.3711	100	0.827	Contact Map
4cbhA	1	0.2918	100	0.873	Contact Map
4u4cA	1	0.4451	100	0.879	Contact Map
4q2cA	1	0.5993	100	0.88	Contact Map
2fwrA	1	0.3145	100	0.883	Contact Map
4w7sA	2	0.3624	100	0.885	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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