3PASE - ECOLI - GREMLIN Contacts

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3PASE - Inorganic triphosphatase

UniProt:	P30871	Sequences: MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETPDNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEVWPNGELPADLASRVQPLFSTDFYREKWLVAVDGSQIEIALDQGEVKAGEFAEPICELELELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAKADVEQGLEAALELALAQWQYHEELWVRGNDAAKEQVLAAISLVRHTLMLFGGIVPRKASTHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQGKISDSFKRFADIHLSRHAAELKSVFCQPLGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQAWLENWQGLHHAIATGQRIEIEHFRNEANNQEPFWLHSGKR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11603
Length:	433 (407)
Sequences:	1139 (869)
Seq/√Len:	43.1

ECOLI - 3PASE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
286_Q	305_E	5.004	1.00
283_L	305_E	4.265	1.00
182_T	186_Q	3.103	1.00
183_G	186_Q	3.044	1.00
366_R	406_A	2.742	1.00
236_W	257_A	2.723	1.00
283_L	286_Q	2.712	1.00
58_R	69_K	2.571	1.00
69_K	191_K	2.557	1.00
162_E	191_K	2.525	1.00
228_A	264_T	2.439	1.00
160_E	191_K	2.436	1.00
56_R	191_K	2.432	1.00
56_R	160_E	2.421	1.00
366_R	373_T	2.269	1.00
373_T	406_A	2.260	1.00
58_R	191_K	2.241	1.00
252_E	255_L	2.218	1.00
69_K	160_E	2.204	1.00
128_K	139_E	2.195	1.00
406_A	410_R	2.194	1.00
58_R	160_E	2.157	1.00
56_R	69_K	2.141	1.00
256_A	377_D	2.133	0.99
56_R	162_E	2.118	0.99
240_E	306_T	2.070	0.99
255_L	259_S	2.016	0.99
69_K	81_R	2.014	0.99
252_E	377_D	1.934	0.99
146_E	153_A	1.931	0.99
366_R	369_L	1.910	0.99
69_K	143_D	1.910	0.99
252_E	366_R	1.899	0.99
255_L	369_L	1.893	0.99
172_L	175_A	1.891	0.99
252_E	406_A	1.889	0.99
142_L	157_C	1.881	0.99
81_R	191_K	1.875	0.99
143_D	191_K	1.860	0.99
369_L	406_A	1.844	0.99
267_L	378_S	1.842	0.98
69_K	162_E	1.840	0.98
44_P	117_Q	1.836	0.98
373_T	377_D	1.828	0.98
172_L	178_L	1.826	0.98
259_S	369_L	1.784	0.98
58_R	162_E	1.765	0.98
179_V	182_T	1.714	0.98
64_Y	91_P	1.705	0.97
255_L	406_A	1.699	0.97
126_R	143_D	1.689	0.97
252_E	373_T	1.680	0.97
252_E	256_A	1.676	0.97
176_N	179_V	1.655	0.97
252_E	259_S	1.652	0.97
8_K	191_K	1.637	0.97
36_L	56_R	1.633	0.97
366_R	410_R	1.625	0.97
178_L	182_T	1.623	0.97
56_R	83_E	1.622	0.97
36_L	160_E	1.618	0.97
370_P	373_T	1.606	0.96
373_T	410_R	1.605	0.96
402_H	410_R	1.591	0.96
81_R	162_E	1.577	0.96
369_L	373_T	1.571	0.96
69_K	83_E	1.553	0.96
255_L	366_R	1.546	0.95
297_A	301_V	1.543	0.95
252_E	369_L	1.541	0.95
366_R	377_D	1.541	0.95
175_A	178_L	1.535	0.95
175_A	183_G	1.516	0.95
4_E	8_K	1.515	0.95
124_F	156_I	1.512	0.95
369_L	377_D	1.511	0.95
256_A	406_A	1.510	0.95
252_E	410_R	1.509	0.95
373_T	402_H	1.505	0.95
366_R	402_H	1.499	0.95
58_R	81_R	1.496	0.95
254_V	291_I	1.495	0.95
402_H	406_A	1.491	0.95
255_L	373_T	1.488	0.94
178_L	184_L	1.486	0.94
4_E	191_K	1.478	0.94
259_S	366_R	1.469	0.94
81_R	160_E	1.459	0.94
373_T	376_I	1.447	0.94
353_L	368_Q	1.440	0.93
366_R	370_P	1.438	0.93
158_E	191_K	1.436	0.93
172_L	183_G	1.433	0.93
10_I	187_G	1.421	0.93
376_I	406_A	1.420	0.93
259_S	410_R	1.417	0.93
40_Y	69_K	1.415	0.93
260_L	380_L	1.413	0.93
255_L	410_R	1.411	0.93
264_T	381_L	1.410	0.93
143_D	162_E	1.401	0.92
369_L	410_R	1.397	0.92
6_E	191_K	1.382	0.92
174_L	178_L	1.382	0.92
370_P	406_A	1.368	0.92
256_A	373_T	1.367	0.91
36_L	69_K	1.366	0.91
83_E	191_K	1.365	0.91
6_E	69_K	1.364	0.91
141_A	159_L	1.362	0.91
8_K	162_E	1.356	0.91
172_L	182_T	1.355	0.91
56_R	143_D	1.355	0.91
259_S	373_T	1.353	0.91
256_A	292_A	1.342	0.91
225_L	229_L	1.341	0.91
4_E	162_E	1.340	0.91
125_Y	144_Q	1.339	0.91
235_Q	257_A	1.339	0.91
143_D	158_E	1.338	0.91
8_K	160_E	1.333	0.90
139_E	160_E	1.332	0.90
98_L	104_P	1.331	0.90
137_Q	165_S	1.322	0.90
9_F	175_A	1.318	0.90
369_L	376_I	1.313	0.90
229_L	261_V	1.312	0.90
176_N	180_S	1.308	0.90
255_L	376_I	1.303	0.89
58_R	83_E	1.299	0.89
361_L	364_R	1.292	0.89
123_D	148_K	1.291	0.89
36_L	58_R	1.290	0.89
260_L	264_T	1.283	0.89
58_R	158_E	1.282	0.89
120_F	195_G	1.281	0.89
46_N	200_Q	1.269	0.88
350_A	394_W	1.266	0.88
261_V	313_L	1.265	0.88
376_I	410_R	1.265	0.88
264_T	268_F	1.263	0.88
366_R	376_I	1.247	0.87
37_L	123_D	1.245	0.87
56_R	81_R	1.242	0.87
36_L	191_K	1.238	0.87
380_L	395_L	1.233	0.87
35_Q	125_Y	1.226	0.86
6_E	56_R	1.223	0.86
6_E	58_R	1.218	0.86
252_E	376_I	1.216	0.86
259_S	370_P	1.208	0.85
377_D	406_A	1.207	0.85
272_V	316_W	1.205	0.85
259_S	377_D	1.203	0.85
377_D	380_L	1.202	0.85
249_A	253_Q	1.202	0.85
259_S	406_A	1.198	0.85
222_E	322_W	1.184	0.84
377_D	410_R	1.182	0.84
266_M	281_R	1.177	0.84
39_I	118_P	1.176	0.84
376_I	380_L	1.173	0.84
69_K	126_R	1.164	0.83
81_R	143_D	1.163	0.83
58_R	143_D	1.152	0.83
256_A	366_R	1.152	0.83
38_N	124_F	1.151	0.83
66_M	195_G	1.149	0.82
178_L	183_G	1.149	0.82
139_E	164_L	1.148	0.82
40_Y	191_K	1.146	0.82
65_E	156_I	1.145	0.82
377_D	402_H	1.138	0.82
69_K	158_E	1.137	0.82
163_L	171_V	1.135	0.82
147_V	195_G	1.132	0.81
158_E	194_R	1.128	0.81
252_E	370_P	1.126	0.81
170_A	183_G	1.125	0.81
297_A	300_A	1.123	0.81
243_W	250_A	1.122	0.81
259_S	376_I	1.121	0.81
169_R	173_K	1.116	0.81
83_E	158_E	1.114	0.80
66_M	192_A	1.112	0.80
9_F	183_G	1.111	0.80
256_A	259_S	1.102	0.80
242_L	250_A	1.102	0.80
170_A	186_Q	1.101	0.80
255_L	377_D	1.096	0.79
126_R	162_E	1.095	0.79
170_A	175_A	1.085	0.79
259_S	292_A	1.085	0.79
340_R	344_I	1.083	0.78
70_V	84_Y	1.081	0.78
175_A	184_L	1.079	0.78
8_K	81_R	1.077	0.78
392_Q	396_E	1.072	0.78
138_I	161_L	1.069	0.78
9_F	186_Q	1.066	0.77
126_R	158_E	1.063	0.77
136_S	170_A	1.059	0.77
139_E	191_K	1.059	0.77
379_I	394_W	1.053	0.76
168_T	172_L	1.053	0.76
292_A	370_P	1.052	0.76
172_L	184_L	1.050	0.76
83_E	162_E	1.050	0.76
214_H	384_G	1.049	0.76
126_R	191_K	1.045	0.76
256_A	410_R	1.044	0.76
368_Q	372_L	1.029	0.75
377_D	399_Q	1.027	0.75
4_E	69_K	1.026	0.75
56_R	67_T	1.026	0.75
292_A	369_L	1.022	0.74
300_A	303_S	1.020	0.74
239_H	257_A	1.015	0.74
36_L	162_E	1.014	0.74
252_E	402_H	1.014	0.74
126_R	160_E	1.011	0.73
67_T	160_E	1.009	0.73
128_K	141_A	1.000	0.73
83_E	143_D	0.999	0.73
180_S	183_G	0.996	0.72
143_D	160_E	0.994	0.72
252_E	262_R	0.993	0.72
4_E	143_D	0.988	0.72
8_K	56_R	0.987	0.72
142_L	159_L	0.984	0.71
172_L	186_Q	0.982	0.71
4_E	158_E	0.981	0.71
255_L	292_A	0.979	0.71
251_K	291_I	0.976	0.71
36_L	40_Y	0.973	0.71
175_A	182_T	0.973	0.71
8_K	69_K	0.973	0.71
83_E	126_R	0.973	0.71
4_E	56_R	0.970	0.70
239_H	242_L	0.968	0.70
136_S	164_L	0.967	0.70
8_K	58_R	0.961	0.70
353_L	372_L	0.961	0.70
256_A	369_L	0.959	0.69
252_E	292_A	0.957	0.69
369_L	402_H	0.951	0.69
290_T	296_S	0.950	0.69
40_Y	58_R	0.942	0.68
342_A	346_L	0.941	0.68
256_A	405_I	0.940	0.68
370_P	410_R	0.939	0.68
38_N	60_E	0.939	0.68
6_E	162_E	0.938	0.68
399_Q	403_H	0.938	0.68
139_E	143_D	0.938	0.68
172_L	176_N	0.935	0.67
158_E	162_E	0.934	0.67
258_I	288_E	0.933	0.67
221_V	271_I	0.929	0.67
239_H	381_L	0.929	0.67
168_T	175_A	0.927	0.67
140_I	159_L	0.922	0.66
240_E	244_V	0.920	0.66
256_A	376_I	0.917	0.66
56_R	126_R	0.917	0.66
239_H	253_Q	0.917	0.66
6_E	83_E	0.917	0.66
170_A	174_L	0.916	0.66
219_A	223_Q	0.916	0.66
124_F	141_A	0.911	0.65
11_V	142_L	0.909	0.65
43_T	111_D	0.907	0.65
65_E	85_N	0.904	0.65
69_K	139_E	0.901	0.65
269_G	281_R	0.899	0.64
253_Q	381_L	0.898	0.64
60_E	244_V	0.898	0.64
262_R	373_T	0.898	0.64
286_Q	290_T	0.897	0.64
334_I	337_S	0.896	0.64
228_A	232_A	0.891	0.64
55_L	68_M	0.890	0.64
4_E	40_Y	0.890	0.64
336_D	340_R	0.889	0.64
370_P	377_D	0.889	0.64
120_F	196_Y	0.888	0.63
86_V	98_L	0.888	0.63
6_E	143_D	0.887	0.63
292_A	406_A	0.885	0.63
105_N	302_Y	0.885	0.63
56_R	158_E	0.883	0.63
57_I	64_Y	0.877	0.62
5_I	88_L	0.877	0.62
204_A	401_L	0.877	0.62
411_I	415_H	0.871	0.62
122_T	145_G	0.870	0.62
179_V	184_L	0.869	0.62
179_V	183_G	0.866	0.61
233_L	313_L	0.863	0.61
63_R	87_A	0.862	0.61
262_R	410_R	0.860	0.61
5_I	374_R	0.860	0.61
167_D	170_A	0.860	0.61
255_L	370_P	0.859	0.61
8_K	143_D	0.858	0.61
8_K	158_E	0.858	0.61
112_L	311_L	0.858	0.61
4_E	160_E	0.857	0.61
382_L	386_Y	0.855	0.60
6_E	158_E	0.855	0.60
262_R	406_A	0.852	0.60
6_E	160_E	0.848	0.60
35_Q	123_D	0.847	0.60
66_M	145_G	0.847	0.60
283_L	309_A	0.846	0.60
341_F	346_L	0.838	0.59
232_A	235_Q	0.837	0.59
83_E	160_E	0.836	0.59
253_Q	256_A	0.835	0.59
170_A	182_T	0.831	0.58
13_H	157_C	0.831	0.58
4_E	58_R	0.830	0.58
297_A	413_I	0.827	0.58
183_G	187_G	0.827	0.58
370_P	376_I	0.824	0.58
11_V	272_V	0.823	0.58
149_A	199_A	0.823	0.58
192_A	196_Y	0.822	0.57
37_L	121_S	0.820	0.57
145_G	156_I	0.819	0.57
260_L	292_A	0.818	0.57
287_C	305_E	0.815	0.57
263_H	309_A	0.813	0.57
147_V	156_I	0.810	0.56
181_Q	186_Q	0.809	0.56
195_G	198_L	0.809	0.56
229_L	265_L	0.809	0.56
124_F	145_G	0.808	0.56
380_L	410_R	0.805	0.56
14_S	144_Q	0.804	0.56
236_W	254_V	0.801	0.55
280_L	312_A	0.800	0.55
7_L	172_L	0.799	0.55
367_D	370_P	0.794	0.55
67_T	191_K	0.793	0.55
49_R	196_Y	0.789	0.54
68_M	98_L	0.788	0.54
175_A	186_Q	0.785	0.54
207_I	210_T	0.783	0.54
52_D	286_Q	0.782	0.54
255_L	402_H	0.781	0.54
255_L	262_R	0.780	0.53
256_A	402_H	0.778	0.53
286_Q	306_T	0.778	0.53
342_A	349_H	0.775	0.53
281_R	365_Y	0.773	0.53
230_E	318_V	0.766	0.52
284_L	309_A	0.766	0.52
134_D	170_A	0.762	0.52
290_T	305_E	0.762	0.52
33_P	125_Y	0.762	0.52
62_G	125_Y	0.761	0.52
67_T	85_N	0.760	0.52
266_M	374_R	0.757	0.51
59_G	64_Y	0.757	0.51
6_E	36_L	0.756	0.51
57_I	65_E	0.754	0.51
228_A	381_L	0.754	0.51
279_H	283_L	0.753	0.51
172_L	179_V	0.753	0.51
292_A	410_R	0.752	0.51
305_E	309_A	0.750	0.51
292_A	366_R	0.750	0.51
4_E	81_R	0.746	0.50
368_Q	414_E	0.745	0.50
31_H	129_W	0.745	0.50
21_D	28_G	0.744	0.50
379_I	395_L	0.742	0.50
349_H	365_Y	0.740	0.50
252_E	380_L	0.740	0.50
360_P	394_W	0.740	0.50
260_L	366_R	0.738	0.49
259_S	402_H	0.737	0.49
259_S	263_H	0.736	0.49
57_I	88_L	0.734	0.49
122_T	156_I	0.731	0.49
286_Q	300_A	0.730	0.49
243_W	254_V	0.730	0.49
350_A	354_K	0.730	0.49
263_H	377_D	0.729	0.49
315_E	319_S	0.727	0.48
369_L	405_I	0.724	0.48
148_K	151_E	0.723	0.48
130_L	136_S	0.723	0.48
58_R	126_R	0.723	0.48
58_R	67_T	0.722	0.48
232_A	264_T	0.722	0.48
301_V	404_A	0.722	0.48
294_A	298_V	0.722	0.48
141_A	164_L	0.721	0.48
54_G	67_T	0.720	0.48
379_I	391_A	0.720	0.48
292_A	373_T	0.720	0.48
280_L	316_W	0.719	0.48
40_Y	143_D	0.718	0.48
60_E	63_R	0.713	0.47
375_D	398_W	0.713	0.47
149_A	154_E	0.712	0.47
254_V	258_I	0.710	0.47
175_A	179_V	0.709	0.47
419_E	423_Q	0.705	0.46
68_M	367_D	0.703	0.46
145_G	311_L	0.700	0.46
232_A	381_L	0.698	0.46
6_E	81_R	0.697	0.46
109_P	241_E	0.694	0.45
39_I	121_S	0.693	0.45
47_W	51_H	0.693	0.45
70_V	141_A	0.693	0.45
346_L	349_H	0.691	0.45
54_G	196_Y	0.690	0.45
9_F	314_T	0.689	0.45
274_R	277_S	0.688	0.45
139_E	162_E	0.686	0.45
366_R	380_L	0.685	0.44
369_L	380_L	0.684	0.44
170_A	178_L	0.683	0.44
215_V	224_G	0.680	0.44
267_L	382_L	0.678	0.44
40_Y	162_E	0.677	0.44
140_I	294_A	0.677	0.44
262_R	369_L	0.676	0.44
263_H	373_T	0.676	0.44
260_L	376_I	0.675	0.44
57_I	67_T	0.675	0.44
145_G	192_A	0.674	0.43
40_Y	83_E	0.672	0.43
40_Y	56_R	0.672	0.43
173_K	176_N	0.672	0.43
34_V	128_K	0.669	0.43
376_I	402_H	0.666	0.43
226_E	317_L	0.665	0.43
126_R	139_E	0.665	0.43
166_G	171_V	0.664	0.43
345_H	349_H	0.663	0.42
362_G	412_E	0.662	0.42
299_T	304_T	0.661	0.42
7_L	175_A	0.660	0.42
370_P	399_Q	0.659	0.42
380_L	406_A	0.657	0.42
357_F	374_R	0.656	0.42
251_K	379_I	0.655	0.42
36_L	141_A	0.654	0.42
8_K	67_T	0.653	0.41
258_I	398_W	0.651	0.41
409_Q	412_E	0.649	0.41
135_G	299_T	0.648	0.41
13_H	224_G	0.648	0.41
40_Y	126_R	0.645	0.41
44_P	114_S	0.645	0.41
54_G	192_A	0.644	0.41
127_E	144_Q	0.644	0.41
52_D	190_S	0.644	0.41
58_R	139_E	0.643	0.41
286_Q	289_A	0.643	0.41
149_A	190_S	0.642	0.40
45_D	257_A	0.642	0.40
55_L	66_M	0.641	0.40
67_T	156_I	0.641	0.40
36_L	143_D	0.641	0.40
344_I	397_N	0.639	0.40
373_T	380_L	0.638	0.40
67_T	162_E	0.637	0.40
145_G	195_G	0.636	0.40
274_R	278_T	0.636	0.40
260_L	410_R	0.633	0.40
269_G	371_R	0.632	0.40
380_L	402_H	0.631	0.39
67_T	143_D	0.629	0.39
180_S	184_L	0.628	0.39
260_L	377_D	0.627	0.39
86_V	90_E	0.625	0.39
411_I	421_N	0.624	0.39
40_Y	160_E	0.623	0.39
254_V	306_T	0.623	0.39
232_A	409_Q	0.621	0.39
145_G	198_L	0.619	0.38
8_K	36_L	0.619	0.38
179_V	186_Q	0.615	0.38
139_E	159_L	0.614	0.38
4_E	36_L	0.610	0.38
151_E	269_G	0.606	0.37
390_V	394_W	0.606	0.37
268_F	378_S	0.604	0.37
252_E	260_L	0.603	0.37
393_A	397_N	0.603	0.37
265_L	283_L	0.599	0.37
118_P	287_C	0.599	0.37
36_L	158_E	0.597	0.36
84_Y	101_E	0.596	0.36
45_D	208_K	0.596	0.36
90_E	97_Q	0.595	0.36
119_L	127_E	0.595	0.36
182_T	187_G	0.593	0.36
287_C	306_T	0.590	0.36
22_H	184_L	0.590	0.36
162_E	194_R	0.586	0.35
372_L	401_L	0.585	0.35
66_M	120_F	0.585	0.35
44_P	323_Q	0.584	0.35
29_E	221_V	0.583	0.35
56_R	139_E	0.583	0.35
391_A	395_L	0.582	0.35
4_E	83_E	0.582	0.35
44_P	204_A	0.581	0.35
256_A	370_P	0.580	0.35
5_I	122_T	0.579	0.35
146_E	155_P	0.579	0.35
233_L	314_T	0.578	0.35
338_F	399_Q	0.577	0.35
255_L	380_L	0.577	0.35
48_L	158_E	0.577	0.35
271_I	334_I	0.575	0.35
139_E	371_R	0.573	0.34
220_D	223_Q	0.573	0.34
4_E	126_R	0.572	0.34
271_I	277_S	0.571	0.34
185_R	240_E	0.570	0.34
122_T	192_A	0.570	0.34
159_L	375_D	0.569	0.34
117_Q	338_F	0.568	0.34
246_G	381_L	0.565	0.34
21_D	64_Y	0.565	0.34
237_Q	241_E	0.565	0.34
45_D	114_S	0.564	0.34
127_E	413_I	0.564	0.34
352_E	355_S	0.563	0.33
52_D	141_A	0.563	0.33
236_W	306_T	0.563	0.33
85_N	122_T	0.562	0.33
47_W	114_S	0.562	0.33
81_R	284_L	0.561	0.33
295_V	363_D	0.560	0.33
313_L	372_L	0.559	0.33
54_G	57_I	0.553	0.33
257_A	380_L	0.553	0.33
276_A	279_H	0.553	0.33
222_E	323_Q	0.552	0.33
13_H	16_V	0.552	0.33
65_E	310_K	0.549	0.32
33_P	127_E	0.548	0.32
272_V	277_S	0.548	0.32
284_L	372_L	0.547	0.32
271_I	333_K	0.547	0.32
253_Q	406_A	0.547	0.32
57_I	66_M	0.547	0.32
55_L	192_A	0.543	0.32
36_L	81_R	0.543	0.32
356_V	371_R	0.542	0.32
219_A	227_A	0.542	0.32
8_K	139_E	0.541	0.32
355_S	358_C	0.538	0.31
13_H	201_G	0.537	0.31
6_E	40_Y	0.537	0.31
110_A	113_A	0.536	0.31
365_Y	409_Q	0.536	0.31
65_E	147_V	0.534	0.31
71_A	112_L	0.534	0.31
147_V	187_G	0.533	0.31
155_P	304_T	0.533	0.31
398_W	401_L	0.531	0.31
293_S	350_A	0.528	0.31
313_L	317_L	0.527	0.31
42_E	251_K	0.526	0.30
273_P	278_T	0.526	0.30
314_T	318_V	0.525	0.30
120_F	192_A	0.525	0.30
269_G	274_R	0.524	0.30
174_L	183_G	0.524	0.30
9_F	23_L	0.524	0.30
176_N	312_A	0.523	0.30
123_D	270_G	0.523	0.30
366_R	405_I	0.523	0.30
104_P	281_R	0.522	0.30
193_A	197_H	0.522	0.30
267_L	348_R	0.521	0.30
342_A	386_Y	0.520	0.30
116_V	422_N	0.520	0.30
168_T	176_N	0.520	0.30
130_L	139_E	0.520	0.30
246_G	265_L	0.520	0.30
276_A	280_L	0.519	0.30
325_F	333_K	0.519	0.30
231_L	235_Q	0.518	0.30
40_Y	158_E	0.513	0.29
263_H	410_R	0.513	0.29
148_K	206_E	0.511	0.29
13_H	105_N	0.507	0.29
5_I	128_K	0.506	0.29
44_P	383_A	0.505	0.29
124_F	195_G	0.504	0.29
182_T	185_R	0.504	0.29
167_D	171_V	0.504	0.29
405_I	413_I	0.504	0.29
260_L	373_T	0.504	0.29
243_W	381_L	0.502	0.29
226_E	320_K	0.501	0.28
65_E	145_G	0.501	0.28
416_F	422_N	0.501	0.28
221_V	421_N	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
5a61A	1	0.9815	100	0.287	Contact Map
3e0sA	1	0.4827	100	0.632	Contact Map
2gfgA	2	0.4203	100	0.734	Contact Map
3tj7A	2	0.388	100	0.738	Contact Map
5a67A	1	0.4319	100	0.746	Contact Map
3bhdA	1	0.448	100	0.754	Contact Map
2acaA	2	0.3903	99.9	0.78	Contact Map
3n10A	2	0.388	99.9	0.781	Contact Map
2eenA	2	0.4018	99.9	0.784	Contact Map
2dc4A	2	0.3718	99.9	0.796	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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