ARTJ - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

ARTJ - ABC transporter arginine-binding protein 1

UniProt:	P30860	Sequences: MKKLVLAALLASFTFGASAAEKINFGVSATYPPFESIGANNEIVGFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTTPYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAFIDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLEKLNNALAAIKADGTYQKISDQWFPQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11628
Length:	243 (224)
Sequences:	20448 (14577)
Seq/√Len:	973.9

ECOLI - ARTJ ARTI HISJ GLNH ARGT YHDW GLTI FLIY EVGS MLTF
BACSU - GLNH YCKB TCYJ ARTP TCYK YXEM TCYA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
22_K	63_T	3.375	1.00
26_G	81_Y	3.347	1.00
130_G	168_I	3.287	1.00
57_Q	226_A	2.786	1.00
90_I	95_S	2.372	1.00
24_N	63_T	2.364	1.00
138_Q	152_S	2.347	1.00
153_Y	162_D	2.279	1.00
102_T	225_A	2.263	1.00
77_K	97_Q	2.102	1.00
90_I	206_G	2.071	1.00
75_S	81_Y	2.064	1.00
138_Q	142_Q	2.058	1.00
155_S	158_N	2.041	1.00
24_N	65_T	2.024	1.00
98_V	208_A	2.001	1.00
99_S	217_L	1.984	1.00
22_K	61_E	1.975	1.00
128_R	151_V	1.938	1.00
159_A	171_V	1.922	1.00
57_Q	223_A	1.920	1.00
232_T	235_K	1.920	1.00
209_V	217_L	1.907	1.00
92_P	95_S	1.893	1.00
55_C	62_C	1.883	1.00
53_A	56_K	1.882	1.00
38_G	44_V	1.879	1.00
173_G	178_V	1.848	1.00
234_Q	238_D	1.848	1.00
162_D	167_R	1.835	1.00
217_L	221_N	1.797	1.00
225_A	229_A	1.789	1.00
119_K	123_D	1.754	1.00
128_R	149_K	1.745	1.00
25_F	51_A	1.685	1.00
114_K	166_G	1.680	1.00
209_V	220_L	1.679	1.00
120_T	123_D	1.670	1.00
53_A	232_T	1.670	1.00
75_S	80_K	1.666	1.00
53_A	227_I	1.644	1.00
112_I	178_V	1.639	1.00
102_T	221_N	1.637	1.00
38_G	42_E	1.621	1.00
85_I	207_I	1.616	1.00
106_E	204_G	1.599	1.00
53_A	57_Q	1.589	1.00
140_Y	144_Q	1.574	1.00
114_K	117_T	1.558	1.00
214_K	218_E	1.525	1.00
67_H	75_S	1.501	1.00
210_R	213_N	1.501	1.00
133_N	154_D	1.472	1.00
110_V	175_T	1.414	1.00
72_L	84_V	1.412	1.00
49_D	239_Q	1.411	1.00
57_Q	230_D	1.398	1.00
25_F	83_A	1.396	1.00
219_K	222_N	1.390	1.00
218_E	222_N	1.382	1.00
101_T	221_N	1.378	1.00
15_F	19_A	1.378	1.00
139_K	143_D	1.372	1.00
175_T	179_N	1.371	1.00
29_A	66_N	1.353	1.00
36_S	44_V	1.341	1.00
37_I	66_N	1.340	1.00
58_M	223_A	1.337	1.00
54_L	223_A	1.314	1.00
48_I	52_K	1.313	1.00
128_R	169_D	1.310	1.00
127_K	169_D	1.302	1.00
99_S	212_D	1.298	1.00
162_D	168_I	1.284	1.00
14_T	17_A	1.283	1.00
223_A	226_A	1.275	1.00
51_A	85_I	1.258	1.00
109_A	137_H	1.233	1.00
16_G	20_A	1.230	1.00
79_R	210_R	1.229	1.00
60_A	219_K	1.219	1.00
73_I	98_V	1.216	1.00
142_Q	152_S	1.196	1.00
52_K	64_F	1.191	1.00
113_A	170_G	1.187	1.00
46_F	237_S	1.185	1.00
129_I	170_G	1.184	1.00
74_P	77_K	1.177	1.00
161_I	164_K	1.174	1.00
228_K	233_Y	1.172	1.00
226_A	230_D	1.169	1.00
88_M	208_A	1.166	1.00
74_P	78_F	1.155	1.00
219_K	223_A	1.153	1.00
99_S	214_K	1.136	1.00
161_I	165_N	1.136	1.00
223_A	227_I	1.135	1.00
47_D	104_Y	1.129	1.00
214_K	217_L	1.119	1.00
111_V	170_G	1.116	1.00
68_A	71_S	1.115	1.00
133_N	152_S	1.109	1.00
154_D	158_N	1.095	1.00
15_F	18_S	1.095	1.00
21_E	60_A	1.095	1.00
130_G	153_Y	1.094	1.00
163_L	168_I	1.065	1.00
44_V	49_D	1.064	1.00
153_Y	159_A	1.063	1.00
99_S	211_P	1.059	1.00
180_E	184_T	1.058	1.00
131_M	138_Q	1.053	1.00
84_V	88_M	1.043	1.00
163_L	171_V	1.034	1.00
118_Y	123_D	1.030	1.00
215_A	219_K	1.022	1.00
49_D	52_K	1.006	1.00
67_H	81_Y	1.000	1.00
115_K	189_G	1.000	1.00
185_N	188_L	0.995	1.00
51_A	64_F	0.994	1.00
49_D	240_W	0.993	1.00
222_N	226_A	0.993	1.00
83_A	220_L	0.987	1.00
232_T	236_I	0.987	1.00
46_F	236_I	0.986	1.00
25_F	62_C	0.981	1.00
52_K	56_K	0.980	1.00
157_Q	161_I	0.980	1.00
37_I	41_N	0.979	1.00
113_A	117_T	0.976	1.00
101_T	220_L	0.975	1.00
102_T	228_K	0.973	1.00
93_E	96_K	0.962	1.00
73_I	88_M	0.960	1.00
50_L	233_Y	0.958	1.00
43_I	48_I	0.941	1.00
164_K	185_N	0.937	1.00
132_E	135_T	0.933	1.00
139_K	142_Q	0.932	1.00
158_N	161_I	0.929	1.00
29_A	43_I	0.926	1.00
221_N	225_A	0.920	1.00
164_K	187_Q	0.904	1.00
51_A	62_C	0.899	1.00
54_L	220_L	0.897	1.00
83_A	209_V	0.895	1.00
57_Q	232_T	0.892	1.00
32_P	36_S	0.890	1.00
108_S	175_T	0.885	1.00
100_F	208_A	0.884	1.00
156_Y	173_G	0.883	1.00
140_Y	143_D	0.883	1.00
227_I	232_T	0.882	1.00
95_S	211_P	0.881	1.00
20_A	24_N	0.881	1.00
13_F	16_G	0.866	1.00
233_Y	237_S	0.865	1.00
23_I	83_A	0.862	1.00
37_I	43_I	0.861	1.00
42_E	52_K	0.859	1.00
234_Q	237_S	0.859	1.00
92_P	96_K	0.854	1.00
130_G	159_A	0.851	1.00
107_N	176_A	0.849	1.00
151_V	162_D	0.845	1.00
77_K	98_V	0.839	1.00
53_A	223_A	0.836	1.00
51_A	207_I	0.835	1.00
71_S	75_S	0.834	1.00
91_T	94_R	0.822	1.00
50_L	227_I	0.819	1.00
124_L	170_G	0.816	1.00
221_N	224_L	0.815	1.00
122_A	125_K	0.810	1.00
58_M	219_K	0.807	1.00
46_F	233_Y	0.800	1.00
84_V	208_A	0.798	1.00
215_A	218_E	0.796	1.00
13_F	17_A	0.795	1.00
27_V	64_F	0.793	1.00
23_I	60_A	0.793	1.00
24_N	82_D	0.788	1.00
89_D	203_T	0.786	1.00
235_K	238_D	0.784	1.00
106_E	202_G	0.782	1.00
226_A	229_A	0.777	1.00
227_I	230_D	0.777	1.00
17_A	20_A	0.775	1.00
51_A	83_A	0.774	1.00
125_K	147_E	0.772	1.00
69_F	72_L	0.770	1.00
235_K	239_Q	0.769	1.00
83_A	207_I	0.767	1.00
22_K	60_A	0.765	1.00
34_F	105_Y	0.761	1.00
57_Q	227_I	0.758	1.00
111_V	172_F	0.755	1.00
54_L	58_M	0.749	1.00
23_I	55_C	0.748	1.00
73_I	77_K	0.745	1.00
213_N	216_L	0.740	1.00
164_K	189_G	0.737	1.00
90_I	103_P	0.731	1.00
27_V	48_I	0.723	1.00
52_K	62_C	0.720	1.00
17_A	21_E	0.720	1.00
222_N	225_A	0.717	1.00
142_Q	150_T	0.716	1.00
180_E	183_K	0.710	1.00
54_L	85_I	0.709	1.00
151_V	168_I	0.707	1.00
27_V	86_S	0.707	1.00
107_N	175_T	0.703	1.00
141_I	150_T	0.702	1.00
145_H	148_V	0.700	1.00
101_T	207_I	0.699	1.00
158_N	162_D	0.698	1.00
227_I	233_Y	0.698	1.00
76_L	98_V	0.695	1.00
218_E	221_N	0.691	1.00
71_S	74_P	0.691	1.00
160_F	164_K	0.690	1.00
53_A	236_I	0.689	1.00
179_N	183_K	0.689	1.00
65_T	80_K	0.689	1.00
14_T	18_S	0.688	1.00
25_F	64_F	0.686	1.00
79_R	212_D	0.683	1.00
44_V	240_W	0.677	1.00
108_S	201_F	0.674	1.00
67_H	72_L	0.674	1.00
110_V	178_V	0.674	1.00
38_G	41_N	0.674	1.00
227_I	231_G	0.670	1.00
103_P	106_E	0.670	1.00
76_L	81_Y	0.669	1.00
36_S	240_W	0.667	1.00
130_G	162_D	0.666	1.00
225_A	228_K	0.663	1.00
101_T	209_V	0.658	1.00
48_I	64_F	0.658	1.00
18_S	21_E	0.655	1.00
76_L	84_V	0.654	1.00
26_G	72_L	0.654	1.00
65_T	81_Y	0.653	1.00
76_L	210_R	0.652	1.00
94_R	100_F	0.652	1.00
58_M	216_L	0.647	1.00
17_A	60_A	0.646	1.00
99_S	213_N	0.640	1.00
128_R	168_I	0.636	1.00
50_L	224_L	0.631	1.00
116_D	166_G	0.629	1.00
28_S	69_F	0.628	1.00
153_Y	168_I	0.628	1.00
55_C	58_M	0.627	1.00
186_P	189_G	0.626	1.00
108_S	199_Q	0.625	1.00
16_G	19_A	0.622	1.00
77_K	210_R	0.620	1.00
109_A	172_F	0.619	1.00
100_F	206_G	0.617	1.00
108_S	202_G	0.617	1.00
28_S	35_E	0.616	1.00
112_I	160_F	0.612	1.00
55_C	60_A	0.612	1.00
51_A	55_C	0.610	1.00
111_V	124_L	0.609	1.00
164_K	188_L	0.608	1.00
132_E	156_Y	0.606	1.00
69_F	88_M	0.604	1.00
227_I	236_I	0.603	1.00
141_I	172_F	0.602	1.00
88_M	98_V	0.599	1.00
29_A	37_I	0.599	1.00
207_I	220_L	0.594	1.00
90_I	100_F	0.593	1.00
47_D	87_G	0.591	1.00
28_S	132_E	0.589	1.00
29_A	35_E	0.588	1.00
129_I	141_I	0.587	1.00
31_Y	87_G	0.586	1.00
39_A	44_V	0.582	1.00
173_G	177_V	0.581	1.00
187_Q	190_V	0.580	1.00
89_D	94_R	0.579	1.00
31_Y	69_F	0.577	1.00
117_T	169_D	0.577	1.00
231_G	234_Q	0.577	1.00
27_V	43_I	0.576	1.00
32_P	184_T	0.576	1.00
101_T	224_L	0.576	1.00
57_Q	219_K	0.574	1.00
136_T	203_T	0.574	1.00
197_D	200_Y	0.573	1.00
131_M	152_S	0.572	1.00
49_D	236_I	0.572	1.00
23_I	216_L	0.566	1.00
178_V	182_L	0.564	1.00
26_G	84_V	0.562	1.00
65_T	75_S	0.561	1.00
231_G	235_K	0.558	1.00
101_T	217_L	0.556	1.00
196_T	199_Q	0.556	1.00
162_D	165_N	0.551	1.00
89_D	136_T	0.550	1.00
185_N	189_G	0.550	1.00
105_Y	205_L	0.547	1.00
56_K	232_T	0.545	1.00
112_I	182_L	0.545	1.00
13_F	210_R	0.544	1.00
35_E	86_S	0.543	1.00
209_V	213_N	0.543	1.00
26_G	75_S	0.536	1.00
107_N	205_L	0.532	1.00
131_M	150_T	0.530	1.00
151_V	167_R	0.528	1.00
20_A	82_D	0.527	1.00
236_I	239_Q	0.525	1.00
181_W	184_T	0.524	1.00
179_N	182_L	0.524	1.00
110_V	195_V	0.523	1.00
140_Y	201_F	0.518	1.00
99_S	209_V	0.513	1.00
26_G	67_H	0.511	1.00
174_D	177_V	0.510	1.00
69_F	94_R	0.510	1.00
102_T	224_L	0.508	1.00
182_L	185_N	0.506	1.00
133_N	138_Q	0.505	1.00
118_Y	127_K	0.504	1.00
43_I	66_N	0.503	1.00
141_I	145_H	0.503	1.00
95_S	99_S	0.502	1.00
40_N	44_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3kbrA	4	0.93	100	0.239	Contact Map
4powA	1	0.9095	100	0.239	Contact Map
3k4uA	5	0.9177	100	0.246	Contact Map
3hv1A	2	0.9794	100	0.25	Contact Map
2vhaA	2	0.9671	100	0.251	Contact Map
1xt8A	1	0.9218	100	0.252	Contact Map
1pb7A	1	0.9424	100	0.254	Contact Map
4ohnA	1	0.9588	100	0.257	Contact Map
2ieeA	1	0.9342	100	0.257	Contact Map
3i6vA	1	0.8724	100	0.259	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0087 seconds.