GREMLIN Database
RNB - Exoribonuclease 2
UniProt: P30850 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11620
Length: 644 (613)
Sequences: 3691 (2269)
Seq/√Len: 91.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
190_E299_E4.7811.00
289_S293_T4.7131.00
278_V306_E4.6781.00
565_A625_D4.2241.00
181_E240_K3.9341.00
131_E146_E3.8401.00
193_T278_V3.6801.00
203_A314_D3.6751.00
44_Y73_A3.6661.00
215_K223_Q3.4981.00
563_R625_D3.4131.00
195_L215_K3.0981.00
219_D287_T3.0141.00
221_K287_T2.9601.00
175_P178_V2.8471.00
59_R80_E2.8191.00
281_V305_I2.8051.00
176_D180_T2.7751.00
394_I489_L2.7101.00
227_A283_A2.6911.00
412_I528_T2.6691.00
493_A507_N2.5711.00
44_Y62_A2.5181.00
317_S321_E2.5161.00
185_E188_V2.4891.00
236_A239_S2.4871.00
47_P50_Q2.4841.00
302_A512_K2.4661.00
90_V97_L2.4321.00
566_A578_V2.4221.00
190_E301_F2.4211.00
212_L389_V2.4091.00
285_R301_F2.3921.00
90_V119_N2.3701.00
197_F305_I2.3511.00
39_D59_R2.3361.00
61_I77_E2.3351.00
63_V74_E2.3251.00
26_V51_M2.3041.00
24_G36_L2.2951.00
568_I618_Y2.2671.00
223_Q285_R2.2581.00
197_F308_K2.2521.00
274_R277_E2.2431.00
317_S383_R2.2171.00
369_G373_E2.2081.00
246_K527_I2.1901.00
281_V303_A2.1641.00
283_A303_A2.1641.00
287_T296_D2.1501.00
565_A623_V2.1081.00
88_G99_I2.0921.00
23_E59_R2.0681.00
576_M589_I2.0671.00
232_T505_M2.0611.00
596_A599_D2.0441.00
149_Q166_A2.0231.00
415_V478_S2.0141.00
302_A516_K2.0101.00
249_A534_R2.0031.00
327_Q338_R1.9961.00
225_I285_R1.9851.00
349_E353_N1.9591.00
250_F534_R1.9581.00
204_S365_R1.9461.00
597_V611_Q1.9271.00
600_E612_I1.9241.00
398_I489_L1.9241.00
563_R627_T1.9231.00
196_D336_Q1.9151.00
182_M185_E1.9041.00
412_I506_I1.8941.00
288_L395_A1.8911.00
175_P244_A1.8881.00
252_N538_N1.8861.00
208_M310_K1.8671.00
417_M482_G1.8661.00
126_D153_F1.8571.00
192_L285_R1.8541.00
415_V482_G1.8341.00
216_A342_Q1.8331.00
217_L221_K1.8111.00
36_L46_I1.8081.00
574_G577_R1.7941.00
205_T208_M1.7871.00
529_V533_E1.7801.00
27_K37_E1.7661.00
23_E61_I1.7641.00
534_R537_L1.7541.00
200_I388_I1.7451.00
130_A145_A1.7381.00
221_K290_A1.7341.00
178_V244_A1.7281.00
557_K560_T1.7171.00
217_L223_Q1.7141.00
503_G531_M1.7131.00
574_G588_F1.7131.00
341_A345_Q1.7091.00
181_E239_S1.7051.00
431_L464_L1.7031.00
589_I624_I1.7011.00
246_K530_Q1.7001.00
591_A609_T1.6701.00
283_A301_F1.6671.00
255_P545_V1.6601.00
85_R131_E1.6551.00
367_I378_V1.6541.00
369_G375_L1.6431.00
288_L294_I1.6381.00
293_T350_W1.6331.00
214_A339_L1.6321.00
133_R146_E1.6301.00
412_I531_M1.6091.00
196_D308_K1.6051.00
227_A303_A1.6031.00
192_L303_A1.6021.00
213_F227_A1.6011.00
345_Q384_I1.6001.00
427_L431_L1.5991.00
250_F503_G1.5961.00
223_Q287_T1.5931.00
102_D127_W1.5901.00
225_I283_A1.5881.00
341_A344_C1.5791.00
216_A339_L1.5651.00
113_R118_L1.5591.00
549_L552_R1.5551.00
348_G391_E1.5511.00
221_K295_E1.5511.00
427_L468_I1.5501.00
348_G387_R1.5501.00
242_D502_Y1.5451.00
59_R79_V1.5371.00
417_M476_E1.5301.00
226_V286_M1.5281.00
217_L220_D1.5191.00
183_L186_G1.5091.00
383_R386_N1.5011.00
197_F281_V1.4961.00
242_D509_R1.4891.00
186_G193_T1.4881.00
275_A307_S1.4831.00
62_A75_P1.4801.00
276_N306_E1.4741.00
630_E639_I1.4721.00
282_L511_L1.4521.00
198_V336_Q1.4490.99
474_F536_R1.4460.99
36_L62_A1.4190.99
264_R268_D1.4180.99
373_E552_R1.4160.99
186_G304_T1.4140.99
367_I376_D1.4130.99
222_L339_L1.4090.99
403_V407_K1.4000.99
135_H143_F1.3920.99
298_I399_C1.3890.99
319_W334_A1.3880.99
551_A631_V1.3870.99
420_D473_S1.3810.99
282_L512_K1.3780.99
286_M399_C1.3780.99
287_T295_E1.3760.99
320_L341_A1.3750.99
214_A340_L1.3650.99
25_V59_R1.3620.99
98_A109_A1.3620.99
315_Q330_S1.3530.99
298_I403_V1.3500.99
530_Q534_R1.3500.99
608_G617_V1.3470.99
568_I576_M1.3440.99
36_L60_I1.3370.99
631_V638_I1.3360.99
269_D274_R1.3360.99
581_V623_V1.3250.99
555_K633_M1.3230.99
467_R607_N1.3200.99
328_P331_E1.3190.99
348_G352_H1.3120.99
454_R457_D1.3090.99
402_R406_D1.2970.99
181_E236_A1.2950.99
216_A290_A1.2940.99
28_A51_M1.2930.99
212_L340_L1.2930.99
341_A384_I1.2910.99
340_L392_A1.2900.99
21_R61_I1.2900.99
315_Q326_W1.2890.99
217_L287_T1.2850.99
284_C300_F1.2770.99
197_F227_A1.2760.99
294_I399_C1.2620.99
35_F43_S1.2570.99
525_D529_V1.2570.99
193_T304_T1.2560.99
127_W163_V1.2530.99
239_S243_K1.2500.98
315_Q329_E1.2500.98
213_F225_I1.2490.98
54_V75_P1.2470.98
502_Y509_R1.2470.98
250_F538_N1.2460.98
339_L342_Q1.2420.98
86_F130_A1.2400.98
84_T131_E1.2360.98
334_A338_R1.2360.98
512_K516_K1.2340.98
493_A510_L1.2320.98
575_G588_F1.2300.98
244_A247_I1.2290.98
282_L302_A1.2270.98
300_F399_C1.2230.98
320_L338_R1.2150.98
280_P304_T1.2120.98
311_L333_I1.2110.98
284_C399_C1.2070.98
294_I395_A1.2070.98
60_I75_P1.2060.98
576_M594_L1.1990.98
126_D150_Y1.1910.98
26_V34_G1.1900.98
479_T528_T1.1890.98
249_A531_M1.1860.98
265_E270_L1.1840.98
214_A336_Q1.1820.98
165_L259_I1.1770.98
551_A638_I1.1710.98
25_V37_E1.1690.98
37_E43_S1.1660.98
213_F283_A1.1650.98
309_A329_E1.1620.98
451_K455_E1.1560.97
91_Q100_V1.1520.97
319_W337_V1.1510.97
170_L541_A1.1480.97
99_I147_L1.1470.97
129_V149_Q1.1460.97
61_I79_V1.1350.97
317_S386_N1.1330.97
384_I388_I1.1270.97
318_D324_G1.1260.97
50_Q65_H1.1240.97
571_I576_M1.1220.97
213_F308_K1.1220.97
99_I145_A1.1220.97
602_V606_E1.1200.97
167_R544_D1.1200.97
168_H544_D1.1190.97
436_L461_T1.1180.97
289_S295_E1.1140.97
448_G451_K1.1110.97
203_A315_Q1.1090.97
252_N541_A1.1090.97
131_E148_T1.1080.97
619_K622_D1.1070.97
312_V315_Q1.1050.97
164_T548_W1.1040.97
99_I130_A1.0990.97
456_L464_L1.0980.97
99_I128_A1.0920.96
103_H167_R1.0920.96
326_W330_S1.0880.96
160_P549_L1.0860.96
164_T541_A1.0750.96
599_D611_Q1.0750.96
602_V605_Q1.0740.96
590_P593_F1.0720.96
90_V99_I1.0670.96
61_I76_E1.0660.96
589_I593_F1.0640.96
85_R148_T1.0630.96
197_F213_F1.0630.96
404_L507_N1.0600.96
250_F531_M1.0590.96
224_L392_A1.0570.96
320_L337_V1.0570.96
192_L301_F1.0560.96
626_V640_A1.0540.96
201_D210_D1.0540.96
275_A309_A1.0520.96
26_V54_V1.0500.96
185_E233_A1.0490.96
197_F212_L1.0470.95
171_E537_L1.0460.95
510_L514_V1.0450.95
190_E285_R1.0430.95
34_G75_P1.0380.95
611_Q614_G1.0360.95
326_W329_E1.0360.95
321_E383_R1.0350.95
208_M274_R1.0350.95
403_V514_V1.0330.95
22_A62_A1.0310.95
202_S316_V1.0300.95
319_W330_S1.0280.95
203_A312_V1.0270.95
198_V311_L1.0270.95
587_A640_A1.0220.95
197_F225_I1.0220.95
415_V476_E1.0200.95
404_L511_L1.0180.95
251_T258_N1.0160.95
364_Y584_G1.0150.95
182_M188_V1.0150.95
153_F156_D1.0130.95
599_D616_T1.0120.95
401_A493_A1.0120.95
27_K56_H1.0120.95
224_L288_L1.0110.95
278_V304_T1.0060.94
405_R491_A1.0040.94
202_S312_V1.0030.94
344_C391_E1.0010.94
431_L452_L1.0000.94
595_H599_D0.9960.94
222_L346_R0.9940.94
38_V41_Q0.9940.94
219_D295_E0.9920.94
402_R491_A0.9880.94
54_V60_I0.9880.94
632_R635_T0.9870.94
300_F400_A0.9830.94
198_V337_V0.9770.93
449_F471_F0.9760.93
631_V635_T0.9660.93
62_A73_A0.9650.93
221_K289_S0.9650.93
130_A147_L0.9630.93
64_I71_E0.9620.93
431_L436_L0.9600.93
128_A147_L0.9600.93
366_F546_G0.9570.93
161_W545_V0.9530.93
276_N307_S0.9520.93
365_R380_E0.9520.93
351_R391_E0.9510.93
628_I638_I0.9480.92
118_L146_E0.9460.92
192_L197_F0.9420.92
207_D499_I0.9410.92
560_T564_F0.9410.92
428_A438_V0.9340.92
401_A507_N0.9340.92
75_P78_L0.9320.92
232_T512_K0.9300.92
244_A248_R0.9300.92
210_D313_Y0.9290.92
286_M294_I0.9290.92
88_G130_A0.9280.92
110_I145_A0.9280.92
217_L295_E0.9270.92
20_P63_V0.9270.92
311_L337_V0.9260.91
343_I392_A0.9250.91
34_G51_M0.9240.91
182_M186_G0.9220.91
346_R349_E0.9210.91
199_T208_M0.9190.91
477_I494_T0.9190.91
531_M534_R0.9160.91
384_I387_R0.9160.91
576_M618_Y0.9160.91
220_D290_A0.9150.91
300_F403_V0.9120.91
83_L135_H0.9110.91
102_D163_V0.9090.91
407_K514_V0.9080.91
551_A636_R0.9050.91
585_A638_I0.9040.90
576_M624_I0.9020.90
233_A302_A0.9000.90
119_N122_F0.8980.90
382_R386_N0.8970.90
197_F283_A0.8970.90
213_F303_A0.8970.90
631_V634_E0.8960.90
567_E581_V0.8950.90
456_L465_D0.8920.90
566_A580_L0.8900.90
373_E556_D0.8900.90
210_D500_R0.8900.90
319_W338_R0.8890.90
233_A512_K0.8890.90
56_H105_L0.8880.90
577_R588_F0.8870.90
109_A112_C0.8860.90
44_Y64_I0.8860.90
356_L361_R0.8840.89
318_D322_N0.8840.89
93_K96_R0.8810.89
207_D390_E0.8810.89
284_C400_A0.8780.89
405_R413_Y0.8760.89
429_A605_Q0.8740.89
314_D318_D0.8730.89
195_L213_F0.8720.89
354_H489_L0.8700.89
380_E386_N0.8700.89
403_V515_I0.8680.89
430_L467_R0.8680.89
170_L259_I0.8660.89
207_D253_Y0.8650.88
164_T545_V0.8640.88
21_R76_E0.8640.88
28_A107_K0.8630.88
213_F285_R0.8620.88
240_K243_K0.8590.88
578_V589_I0.8590.88
201_D393_M0.8560.88
98_A111_P0.8540.88
201_D253_Y0.8540.88
92_G97_L0.8530.88
354_H398_I0.8530.88
26_V36_L0.8530.88
292_G343_I0.8510.88
323_T327_Q0.8500.88
128_A150_Y0.8490.88
192_L305_I0.8490.88
253_Y500_R0.8460.87
36_L75_P0.8460.87
333_I337_V0.8450.87
55_M83_L0.8440.87
598_R612_I0.8430.87
134_R144_Y0.8420.87
554_L628_I0.8410.87
404_L411_G0.8400.87
311_L330_S0.8380.87
571_I609_T0.8380.87
336_Q339_L0.8380.87
453_R456_L0.8360.87
382_R387_R0.8360.87
227_A285_R0.8360.87
195_L225_I0.8360.87
255_P374_V0.8350.87
396_A495_W0.8310.86
452_L456_L0.8310.86
316_V320_L0.8290.86
309_A315_Q0.8280.86
201_D500_R0.8240.86
272_S499_I0.8230.86
65_H74_E0.8230.86
175_P247_I0.8220.86
220_D287_T0.8190.86
298_I402_R0.8190.86
155_D160_P0.8170.85
170_L537_L0.8120.85
286_M395_A0.8110.85
526_E530_Q0.8100.85
30_E33_F0.8090.85
225_I301_F0.8080.85
209_D500_R0.8020.84
580_L583_N0.8010.84
238_G243_K0.8010.84
447_D451_K0.8010.84
210_D393_M0.8010.84
553_F557_K0.8000.84
596_A616_T0.7990.84
122_F128_A0.7970.84
26_V75_P0.7970.84
54_V78_L0.7960.84
171_E247_I0.7950.84
81_P135_H0.7910.84
208_M312_V0.7910.84
50_Q72_S0.7890.83
216_A335_E0.7860.83
210_D253_Y0.7860.83
196_D213_F0.7850.83
199_T307_S0.7850.83
313_Y500_R0.7850.83
46_I50_Q0.7850.83
103_H106_L0.7840.83
123_K126_D0.7840.83
404_L510_L0.7830.83
367_I375_L0.7820.83
97_L124_E0.7810.83
317_S384_I0.7790.83
565_A581_V0.7780.83
472_Q485_F0.7780.83
201_D209_D0.7780.83
576_M593_F0.7740.82
201_D313_Y0.7740.82
436_L459_Q0.7730.82
350_W353_N0.7730.82
342_Q346_R0.7720.82
22_A38_V0.7720.82
292_G346_R0.7700.82
462_G579_R0.7700.82
413_Y481_P0.7680.82
210_D261_M0.7650.81
90_V147_L0.7640.81
196_D309_A0.7630.81
249_A530_Q0.7630.81
393_M497_S0.7620.81
194_A308_K0.7620.81
314_D383_R0.7620.81
311_L315_Q0.7590.81
338_R341_A0.7570.81
109_A113_R0.7570.81
28_A34_G0.7570.81
343_I346_R0.7550.81
208_M264_R0.7550.81
45_F48_P0.7550.81
460_P623_V0.7530.80
218_P221_K0.7510.80
565_A582_D0.7500.80
21_R63_V0.7480.80
209_D393_M0.7480.80
89_K154_G0.7470.80
206_E268_D0.7470.80
178_V181_E0.7460.80
22_A36_L0.7440.80
209_D313_Y0.7440.80
133_R144_Y0.7430.80
235_I266_L0.7430.80
123_K153_F0.7420.79
133_R136_P0.7410.79
424_A449_F0.7410.79
348_G358_F0.7410.79
300_F511_L0.7410.79
132_M135_H0.7400.79
202_S310_K0.7390.79
123_K264_R0.7390.79
364_Y550_Y0.7370.79
285_R299_E0.7370.79
331_E334_A0.7350.79
207_D475_A0.7310.78
309_A333_I0.7300.78
547_D570_D0.7290.78
400_A493_A0.7280.78
327_Q331_E0.7250.78
275_A310_K0.7250.78
254_L545_V0.7240.78
628_I640_A0.7220.78
50_Q74_E0.7220.78
495_W508_H0.7210.78
209_D253_Y0.7180.77
320_L384_I0.7170.77
322_N338_R0.7140.77
177_G240_K0.7120.77
578_V587_A0.7100.76
98_A142_S0.7090.76
377_I585_A0.7090.76
207_D416_H0.7080.76
481_P491_A0.7070.76
291_D346_R0.7070.76
567_E623_V0.7040.76
238_G246_K0.7030.76
568_I624_I0.7020.76
55_M82_F0.7010.76
55_M106_L0.7010.76
564_F628_I0.7010.76
344_C384_I0.7010.76
269_D277_E0.7000.75
29_T33_F0.7000.75
344_C348_G0.6990.75
351_R356_L0.6980.75
311_L319_W0.6970.75
202_S386_N0.6970.75
89_K127_W0.6940.75
270_L279_R0.6910.74
414_N475_A0.6900.74
173_E176_D0.6900.74
270_L277_E0.6880.74
207_D271_C0.6870.74
572_S588_F0.6860.74
83_L86_F0.6860.74
132_M136_P0.6840.74
335_E339_L0.6840.74
184_D187_L0.6840.74
506_I527_I0.6820.74
313_Y393_M0.6810.73
393_M500_R0.6810.73
580_L626_V0.6800.73
228_I393_M0.6790.73
46_I73_A0.6780.73
390_E475_A0.6750.73
376_D557_K0.6720.72
601_L604_S0.6680.72
254_L259_I0.6680.72
197_F214_A0.6680.72
347_R350_W0.6660.72
602_V608_G0.6660.72
414_N501_K0.6660.72
436_L452_L0.6650.72
165_L257_F0.6650.72
111_P144_Y0.6650.72
593_F629_A0.6640.72
425_D428_A0.6640.72
566_A624_I0.6640.72
46_I54_V0.6620.71
48_P52_K0.6620.71
390_E497_S0.6620.71
566_A628_I0.6610.71
160_P548_W0.6600.71
224_L343_I0.6600.71
399_C402_R0.6590.71
109_A145_A0.6580.71
563_R624_I0.6570.71
96_R111_P0.6560.71
223_Q283_A0.6560.71
321_E384_I0.6560.71
38_V44_Y0.6550.71
210_D497_S0.6550.71
253_Y393_M0.6540.70
184_D188_V0.6540.70
309_A332_A0.6500.70
463_F567_E0.6490.70
364_Y379_A0.6490.70
162_W166_A0.6480.70
261_M313_Y0.6480.70
393_M416_H0.6470.70
92_G124_E0.6470.70
111_P114_A0.6470.70
601_L607_N0.6460.69
507_N511_L0.6440.69
284_C298_I0.6430.69
632_R637_S0.6430.69
288_L292_G0.6420.69
87_V129_V0.6410.69
193_T306_E0.6400.69
201_D273_L0.6400.69
122_F147_L0.6390.69
38_V71_E0.6390.69
125_G153_F0.6370.68
85_R169_N0.6370.68
202_S314_D0.6360.68
228_I272_S0.6360.68
608_G619_K0.6340.68
393_M499_I0.6340.68
416_H486_G0.6340.68
46_I60_I0.6330.68
201_D499_I0.6330.68
554_L585_A0.6330.68
109_A142_S0.6320.68
221_K296_D0.6310.68
178_V247_I0.6310.68
541_A545_V0.6310.68
468_I472_Q0.6300.68
254_L386_N0.6290.67
547_D551_A0.6280.67
201_D390_E0.6280.67
34_G38_V0.6280.67
313_Y499_I0.6270.67
122_F126_D0.6270.67
207_D497_S0.6270.67
417_M532_A0.6270.67
209_D229_A0.6260.67
186_G278_V0.6250.67
598_R611_Q0.6250.67
208_M275_A0.6240.67
210_D390_E0.6240.67
288_L347_R0.6230.67
597_V613_K0.6230.67
216_A222_L0.6230.67
528_T531_M0.6220.67
318_D323_T0.6210.66
126_D264_R0.6210.66
272_S497_S0.6210.66
591_A600_E0.6190.66
205_T260_P0.6190.66
201_D207_D0.6180.66
425_D440_A0.6180.66
106_L109_A0.6170.66
317_S385_A0.6170.66
327_Q334_A0.6160.66
324_G327_Q0.6160.66
97_L119_N0.6150.66
33_F45_F0.6150.66
179_A265_E0.6150.66
206_E499_I0.6150.66
228_I497_S0.6140.66
156_D604_S0.6130.65
91_Q124_E0.6120.65
227_A281_V0.6120.65
205_T310_K0.6110.65
214_A343_I0.6110.65
614_G624_I0.6110.65
386_N489_L0.6100.65
439_D442_E0.6100.65
253_Y390_E0.6100.65
323_T338_R0.6090.65
56_H83_L0.6090.65
195_L308_K0.6080.65
272_S313_Y0.6070.65
535_R542_E0.6070.65
207_D272_S0.6060.65
361_R539_R0.6060.65
170_L473_S0.6060.65
169_N534_R0.6050.64
186_G233_A0.6040.64
442_E445_T0.6030.64
219_D223_Q0.6030.64
207_D210_D0.6020.64
390_E394_I0.6020.64
208_M307_S0.5980.64
202_S208_M0.5980.64
279_R351_R0.5980.64
414_N500_R0.5980.64
404_L514_V0.5970.63
452_L464_L0.5960.63
195_L285_R0.5950.63
129_V166_A0.5950.63
207_D313_Y0.5940.63
55_M80_E0.5940.63
196_D333_I0.5940.63
341_A388_I0.5930.63
227_A548_W0.5930.63
521_T524_Q0.5930.63
235_I505_M0.5920.63
87_V163_V0.5910.63
231_P499_I0.5910.63
178_V241_L0.5910.63
29_T32_G0.5890.62
205_T267_S0.5890.62
277_E307_S0.5880.62
575_G587_A0.5880.62
198_V316_V0.5870.62
46_I75_P0.5870.62
526_E529_V0.5870.62
212_L388_I0.5870.62
253_Y313_Y0.5860.62
469_R535_R0.5860.62
246_K531_M0.5860.62
174_A244_A0.5850.62
555_K630_E0.5850.62
597_V612_I0.5840.62
390_E393_M0.5840.62
201_D414_N0.5830.62
152_T160_P0.5830.62
253_Y499_I0.5820.61
153_F264_R0.5820.61
630_E637_S0.5800.61
593_F624_I0.5800.61
333_I336_Q0.5800.61
186_G281_V0.5800.61
554_L640_A0.5800.61
309_A337_V0.5790.61
159_V163_V0.5790.61
266_L499_I0.5790.61
194_A306_E0.5780.61
158_F257_F0.5780.61
513_A523_P0.5780.61
231_P414_N0.5770.61
423_N564_F0.5770.61
177_G180_T0.5760.61
222_L342_Q0.5760.61
439_D445_T0.5750.61
35_F45_F0.5750.61
375_L378_V0.5750.61
530_Q533_E0.5740.60
494_T501_K0.5740.60
136_P143_F0.5730.60
229_A235_I0.5730.60
552_R555_K0.5730.60
441_E444_L0.5730.60
438_V444_L0.5730.60
210_D499_I0.5730.60
122_F150_Y0.5720.60
507_N510_L0.5720.60
470_R543_R0.5710.60
243_K246_K0.5710.60
331_E335_E0.5710.60
151_I166_A0.5710.60
43_S571_I0.5700.60
202_S205_T0.5690.60
372_G549_L0.5680.60
299_E303_A0.5670.59
449_F468_I0.5670.59
198_V333_I0.5660.59
360_D387_R0.5650.59
207_D273_L0.5650.59
258_N268_D0.5640.59
290_A342_Q0.5640.59
370_E375_L0.5640.59
557_K628_I0.5640.59
337_V341_A0.5640.59
174_A179_A0.5640.59
590_P639_I0.5630.59
547_D586_I0.5620.59
22_A64_I0.5620.59
229_A499_I0.5610.59
89_K634_E0.5590.58
56_H101_P0.5590.58
566_A638_I0.5590.58
274_R279_R0.5580.58
265_E269_D0.5580.58
323_T326_W0.5570.58
201_D497_S0.5570.58
352_H454_R0.5550.58
564_F626_V0.5550.58
276_N309_A0.5530.58
241_L267_S0.5530.58
85_R129_V0.5530.58
360_D382_R0.5530.58
176_D179_A0.5530.58
356_L394_I0.5530.58
251_T260_P0.5520.57
356_L391_E0.5520.57
350_W354_H0.5520.57
199_T275_A0.5520.57
426_A605_Q0.5510.57
199_T310_K0.5510.57
196_D332_A0.5500.57
594_L609_T0.5500.57
206_E256_G0.5500.57
19_T598_R0.5490.57
207_D393_M0.5490.57
243_K632_R0.5480.57
204_S380_E0.5480.57
599_D602_V0.5470.57
329_E332_A0.5470.57
88_G128_A0.5460.57
21_R77_E0.5460.57
441_E445_T0.5450.56
506_I510_L0.5450.56
610_V617_V0.5450.56
185_E280_P0.5450.56
247_I338_R0.5450.56
178_V240_K0.5450.56
158_F162_W0.5440.56
75_P82_F0.5440.56
183_L187_L0.5440.56
282_L300_F0.5440.56
316_V341_A0.5440.56
83_L106_L0.5430.56
228_I499_I0.5410.56
202_S389_V0.5400.56
426_A429_A0.5400.56
39_D187_L0.5400.56
209_D499_I0.5390.56
201_D475_A0.5380.56
451_K468_I0.5380.56
260_P292_G0.5370.55
202_S207_D0.5350.55
29_T43_S0.5350.55
181_E241_L0.5350.55
234_W270_L0.5350.55
192_L195_L0.5350.55
214_A227_A0.5350.55
89_K102_D0.5340.55
583_N640_A0.5340.55
212_L344_C0.5340.55
403_V511_L0.5330.55
194_A349_E0.5330.55
519_T522_R0.5330.55
588_F639_I0.5330.55
207_D500_R0.5320.55
231_P416_H0.5320.55
165_L464_L0.5320.55
235_I475_A0.5320.55
77_E103_H0.5310.55
198_V214_A0.5310.55
200_I210_D0.5310.55
78_L81_P0.5300.54
201_D272_S0.5300.54
252_N310_K0.5290.54
315_Q318_D0.5290.54
126_D155_D0.5290.54
227_A400_A0.5270.54
591_A594_L0.5270.54
271_C393_M0.5260.54
212_L393_M0.5260.54
362_P462_G0.5240.54
235_I486_G0.5240.54
253_Y497_S0.5240.54
74_E78_L0.5240.54
405_R481_P0.5240.54
228_I253_Y0.5230.53
552_R633_M0.5230.53
101_P105_L0.5230.53
26_V46_I0.5220.53
225_I374_V0.5220.53
174_A260_P0.5220.53
36_L73_A0.5210.53
423_N427_L0.5200.53
202_S317_S0.5200.53
36_L51_M0.5200.53
432_K438_V0.5190.53
554_L638_I0.5190.53
218_P295_E0.5190.53
197_F307_S0.5160.52
210_D228_I0.5160.52
314_D385_A0.5160.52
271_C475_A0.5140.52
532_A535_R0.5140.52
55_M135_H0.5130.52
396_A511_L0.5130.52
589_I626_V0.5130.52
477_I495_W0.5120.52
36_L622_D0.5110.52
532_A536_R0.5110.52
208_M385_A0.5100.52
213_F223_Q0.5100.52
597_V615_E0.5090.52
90_V124_E0.5090.52
488_G554_L0.5080.51
390_E416_H0.5080.51
45_F72_S0.5080.51
73_A168_H0.5070.51
215_K218_P0.5060.51
317_S322_N0.5060.51
400_A511_L0.5060.51
231_P475_A0.5060.51
168_H636_R0.5050.51
169_N172_K0.5040.51
82_F106_L0.5040.51
229_A496_T0.5030.51
344_C392_A0.5030.51
261_M500_R0.5030.51
474_F539_R0.5030.51
511_L515_I0.5030.51
228_I313_Y0.5030.51
26_V52_K0.5020.51
235_I239_S0.5020.51
229_A393_M0.5020.51
186_G280_P0.5000.50
157_H549_L0.5000.50
414_N477_I0.5000.50
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2vnuD 1 0.9581 100 0.137 Contact Map
4ifdJ 1 0.972 100 0.139 Contact Map
2id0A 1 0.9798 100 0.147 Contact Map
4ro1A 1 0.8152 100 0.163 Contact Map
4pmwA 1 0.9736 100 0.163 Contact Map
2r7dA 1 0.6894 100 0.414 Contact Map
3bzcA 1 0.7842 99.9 0.886 Contact Map
1go3E 1 0.2453 99.6 0.912 Contact Map
1e3pA 3 0.7034 99.5 0.915 Contact Map
4qjfA 1 0.2438 99.4 0.921 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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