BAES - ECOLI - GREMLIN Contacts

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BAES - Signal transduction histidine-protein kinase BaeS

UniProt:	P30847	Sequences: MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQILRSFEHDNSEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFDKQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLQISAGQRDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11617
Length:	467 (440)
Sequences:	47900 (41989)
Seq/√Len:	2001.7

ECOLI - BAES BARA GLRK PHOQ CUSS TORS QSEC YEDV CREC CPXA ENVZ RSTB RCSD ATOS RCSC ZRAS NARQ NARX BASS DCUS ARCB DPIB EVGS PHOR KDPD YPDA UHPB NTRB
BACSU - YCLK YYCG CSSS YKOH RESE YVRG PHOR YVCQ KINB DCTS YRKQ CITS MALK YCBM YXDK KIND KINE YESM BCES KINA GLNK KINC LIAS YBDK LYTS YWPD COMP YFIJ YDFH NATK DEGS YHCY YXJM
HALSA - Q9HQ15 Q9HQE9 Q9HQG5 Q9HQ16 O51970 Q9HRE4 Q9HRG1 Q9HR10 Q9HNM2 BAT Q9HNA6 Q9HQB9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
391_A	452_S	4.141	1.00
392_D	396_G	3.810	1.00
385_T	456_E	3.703	1.00
431_L	435_E	3.626	1.00
313_V	349_G	3.521	1.00
442_I	454_T	3.343	1.00
263_L	281_L	3.208	1.00
389_T	452_S	3.194	1.00
402_L	445_H	2.961	1.00
338_Q	376_Q	2.934	1.00
369_T	393_S	2.862	1.00
387_R	456_E	2.842	1.00
338_Q	374_S	2.815	1.00
378_S	389_T	2.814	1.00
389_T	454_T	2.796	1.00
349_G	437_H	2.697	1.00
387_R	454_T	2.649	1.00
312_P	348_F	2.636	1.00
380_G	387_R	2.635	1.00
374_S	393_S	2.627	1.00
381_Q	459_L	2.614	1.00
340_S	378_S	2.600	1.00
376_Q	391_A	2.592	1.00
260_R	286_G	2.581	1.00
443_A	453_I	2.572	1.00
446_S	449_G	2.558	1.00
430_C	441_I	2.529	1.00
357_L	434_V	2.529	1.00
398_S	401_Q	2.513	1.00
444_A	454_T	2.476	1.00
267_Q	282_Q	2.474	1.00
406_F	441_I	2.424	1.00
444_A	452_S	2.420	1.00
267_Q	279_A	2.394	1.00
378_S	391_A	2.363	1.00
380_G	389_T	2.337	1.00
312_P	346_T	2.326	1.00
314_D	317_P	2.264	1.00
397_V	405_L	2.262	1.00
434_V	439_G	2.257	1.00
402_L	443_A	2.209	1.00
336_K	374_S	2.200	1.00
401_Q	404_K	2.182	1.00
271_R	274_T	2.180	1.00
440_R	456_E	2.179	1.00
445_H	451_V	2.173	1.00
321_V	355_M	2.156	1.00
340_S	376_Q	2.146	1.00
218_D	221_G	2.142	1.00
311_A	351_R	2.095	1.00
434_V	455_V	2.086	1.00
349_G	354_L	1.992	1.00
326_F	359_N	1.973	1.00
260_R	285_V	1.964	1.00
357_L	433_I	1.953	1.00
404_K	407_E	1.899	1.00
230_L	234_L	1.873	1.00
310_K	348_F	1.853	1.00
289_T	293_D	1.836	1.00
260_R	289_T	1.835	1.00
399_D	402_L	1.833	1.00
330_F	366_L	1.830	1.00
243_D	247_D	1.826	1.00
442_I	456_E	1.825	1.00
216_S	221_G	1.814	1.00
220_L	224_A	1.812	1.00
369_T	373_G	1.808	1.00
202_K	207_D	1.801	1.00
382_R	387_R	1.798	1.00
29_W	33_I	1.796	1.00
401_Q	410_Y	1.789	1.00
357_L	430_C	1.778	1.00
435_E	440_R	1.759	1.00
397_V	401_Q	1.742	1.00
363_E	367_R	1.722	1.00
433_I	437_H	1.714	1.00
373_G	393_S	1.704	1.00
358_F	388_L	1.681	1.00
404_K	410_Y	1.665	1.00
231_A	234_L	1.659	1.00
316_I	320_E	1.630	1.00
241_R	245_M	1.626	1.00
264_E	282_Q	1.620	1.00
397_V	451_V	1.610	1.00
239_Q	243_D	1.581	1.00
263_L	282_Q	1.579	1.00
197_V	222_K	1.571	1.00
360_N	430_C	1.542	1.00
144_I	147_P	1.536	1.00
217_E	221_G	1.530	1.00
350_D	353_R	1.525	1.00
376_Q	393_S	1.516	1.00
369_T	375_L	1.501	1.00
259_L	285_V	1.487	1.00
267_Q	275_P	1.484	1.00
388_L	455_V	1.481	1.00
401_Q	412_T	1.475	1.00
357_L	455_V	1.469	1.00
282_Q	286_G	1.465	1.00
262_E	277_T	1.455	1.00
392_D	450_G	1.452	1.00
238_Q	241_R	1.445	1.00
321_V	351_R	1.430	1.00
406_F	443_A	1.429	1.00
266_I	278_V	1.418	1.00
434_V	441_I	1.407	1.00
402_L	406_F	1.401	1.00
197_V	201_H	1.391	1.00
445_H	448_F	1.388	1.00
353_R	356_Q	1.383	1.00
269_G	274_T	1.369	1.00
353_R	436_A	1.349	1.00
251_E	356_Q	1.346	1.00
316_I	379_A	1.341	1.00
259_L	281_L	1.337	1.00
224_A	228_N	1.335	1.00
314_D	346_T	1.331	1.00
407_E	410_Y	1.330	1.00
386_V	459_L	1.323	1.00
325_A	355_M	1.322	1.00
351_R	355_M	1.318	1.00
398_S	447_P	1.315	1.00
260_R	282_Q	1.310	1.00
231_A	235_E	1.309	1.00
368_Y	411_R	1.290	1.00
353_R	433_I	1.289	1.00
327_R	331_A	1.282	1.00
323_G	339_F	1.279	1.00
182_T	186_A	1.275	1.00
140_V	144_I	1.275	1.00
258_V	284_E	1.273	1.00
432_N	435_E	1.272	1.00
445_H	449_G	1.266	1.00
320_E	339_F	1.265	1.00
258_V	262_E	1.263	1.00
200_T	203_L	1.262	1.00
142_A	145_A	1.261	1.00
263_L	285_V	1.250	1.00
235_E	239_Q	1.234	1.00
318_L	322_A	1.226	1.00
203_L	231_A	1.215	1.00
385_T	440_R	1.208	1.00
406_F	453_I	1.197	1.00
244_F	248_I	1.189	1.00
30_A	34_S	1.184	1.00
202_K	210_T	1.183	1.00
247_D	408_R	1.183	1.00
207_D	210_T	1.180	1.00
137_G	140_V	1.176	1.00
221_G	224_A	1.175	1.00
443_A	451_V	1.169	1.00
341_L	379_A	1.166	1.00
406_F	431_L	1.163	1.00
439_G	457_L	1.160	1.00
220_L	223_L	1.152	1.00
405_L	443_A	1.150	1.00
165_Q	169_L	1.145	1.00
391_A	446_S	1.135	1.00
144_I	149_E	1.131	1.00
266_I	274_T	1.126	1.00
211_R	232_S	1.124	1.00
236_K	240_M	1.102	1.00
83_R	87_H	1.101	1.00
142_A	147_P	1.100	1.00
322_A	326_F	1.098	1.00
399_D	445_H	1.096	1.00
238_Q	242_R	1.089	1.00
142_A	149_E	1.089	1.00
279_A	283_A	1.088	1.00
271_R	275_P	1.086	1.00
262_E	280_S	1.082	1.00
322_A	359_N	1.081	1.00
61_Q	65_H	1.078	1.00
365_S	375_L	1.078	1.00
36_E	40_I	1.076	1.00
143_V	148_V	1.073	1.00
411_R	420_S	1.070	1.00
263_L	278_V	1.066	1.00
308_Y	350_D	1.063	1.00
161_K	165_Q	1.061	1.00
79_F	83_R	1.056	1.00
263_L	267_Q	1.054	1.00
290_K	352_D	1.049	1.00
194_K	197_V	1.046	1.00
227_F	230_L	1.045	1.00
329_R	332_S	1.042	1.00
145_A	148_V	1.040	1.00
313_V	318_L	1.039	1.00
360_N	363_E	1.037	1.00
143_V	147_P	1.035	1.00
187_R	191_A	1.034	1.00
216_S	224_A	1.033	1.00
138_A	141_G	1.032	1.00
28_H	32_R	1.024	1.00
319_L	379_A	1.015	1.00
200_T	226_D	1.013	1.00
316_I	341_L	1.010	1.00
258_V	261_G	1.009	1.00
200_T	227_F	1.002	1.00
146_S	149_E	1.001	1.00
322_A	355_M	1.000	1.00
77_F	80_Q	0.999	1.00
253_R	293_D	0.997	1.00
32_R	164_R	0.994	1.00
261_G	265_A	0.994	1.00
310_K	437_H	0.994	1.00
50_R	53_L	0.992	1.00
293_D	297_Q	0.988	1.00
139_E	142_A	0.984	1.00
294_D	353_R	0.982	1.00
201_H	222_K	0.976	1.00
392_D	451_V	0.975	1.00
44_K	48_E	0.975	1.00
108_W	111_D	0.970	1.00
142_A	146_S	0.970	1.00
276_E	280_S	0.969	1.00
342_P	380_G	0.968	1.00
397_V	402_L	0.964	1.00
145_A	149_E	0.960	1.00
228_N	231_A	0.959	1.00
11_K	218_D	0.958	1.00
354_L	437_H	0.958	1.00
275_P	279_A	0.956	1.00
361_L	453_I	0.954	1.00
260_R	264_E	0.953	1.00
199_G	212_V	0.951	1.00
186_A	190_L	0.949	1.00
164_R	168_W	0.947	1.00
270_V	274_T	0.943	1.00
9_T	187_R	0.942	1.00
200_T	204_A	0.937	1.00
221_G	225_Q	0.933	1.00
397_V	443_A	0.931	1.00
284_E	287_T	0.930	1.00
197_V	226_D	0.922	1.00
85_F	89_N	0.922	1.00
211_R	228_N	0.920	1.00
358_F	362_L	0.920	1.00
143_V	146_S	0.920	1.00
229_Q	233_T	0.920	1.00
179_A	183_F	0.920	1.00
425_L	429_I	0.919	1.00
78_V	82_L	0.918	1.00
408_R	432_N	0.917	1.00
88_D	91_E	0.914	1.00
434_V	457_L	0.911	1.00
140_V	145_A	0.911	1.00
75_D	79_F	0.910	1.00
317_P	321_V	0.910	1.00
243_D	408_R	0.908	1.00
48_E	52_Q	0.907	1.00
361_L	441_I	0.906	1.00
359_N	363_E	0.905	1.00
197_V	200_T	0.905	1.00
86_E	90_S	0.903	1.00
213_T	228_N	0.902	1.00
33_I	36_E	0.902	1.00
326_F	362_L	0.900	1.00
141_G	145_A	0.898	1.00
405_L	453_I	0.898	1.00
33_I	37_R	0.898	1.00
382_R	385_T	0.897	1.00
318_L	349_G	0.896	1.00
137_G	142_A	0.891	1.00
384_K	459_L	0.888	1.00
368_Y	395_P	0.888	1.00
325_A	359_N	0.886	1.00
308_Y	353_R	0.883	1.00
290_K	294_D	0.882	1.00
165_Q	168_W	0.881	1.00
280_S	284_E	0.880	1.00
315_L	388_L	0.877	1.00
184_L	188_G	0.877	1.00
192_P	196_L	0.876	1.00
322_A	325_A	0.876	1.00
361_L	430_C	0.875	1.00
296_H	299_S	0.871	1.00
107_F	110_V	0.869	1.00
362_L	377_I	0.869	1.00
358_F	390_F	0.868	1.00
180_L	184_L	0.866	1.00
323_G	327_R	0.863	1.00
335_L	369_T	0.862	1.00
272_K	275_P	0.861	1.00
245_M	248_I	0.861	1.00
251_E	360_N	0.859	1.00
237_N	240_M	0.858	1.00
370_D	373_G	0.857	1.00
199_G	210_T	0.854	1.00
196_L	200_T	0.849	1.00
88_D	92_D	0.849	1.00
132_P	136_N	0.841	1.00
281_L	285_V	0.839	1.00
382_R	456_E	0.838	1.00
239_Q	242_R	0.835	1.00
355_M	359_N	0.835	1.00
357_L	437_H	0.834	1.00
76_R	79_F	0.834	1.00
203_L	230_L	0.834	1.00
59_G	63_A	0.830	1.00
285_V	289_T	0.830	1.00
283_A	321_V	0.829	1.00
329_R	363_E	0.829	1.00
252_L	288_L	0.828	1.00
361_L	455_V	0.828	1.00
257_A	261_G	0.828	1.00
226_D	229_Q	0.822	1.00
326_F	363_E	0.821	1.00
137_G	141_G	0.821	1.00
55_S	59_G	0.819	1.00
322_A	362_L	0.818	1.00
319_L	358_F	0.818	1.00
43_I	46_G	0.818	1.00
45_H	48_E	0.817	1.00
214_P	225_Q	0.812	1.00
200_T	223_L	0.812	1.00
183_F	187_R	0.806	1.00
265_A	269_G	0.805	1.00
61_Q	64_Q	0.804	1.00
83_R	88_D	0.804	1.00
320_E	324_G	0.803	1.00
397_V	403_Q	0.799	1.00
47_N	51_L	0.798	1.00
276_E	279_A	0.795	1.00
153_R	157_I	0.795	1.00
62_Y	66_G	0.794	1.00
250_H	254_T	0.794	1.00
103_W	110_V	0.792	1.00
138_A	142_A	0.791	1.00
78_V	81_I	0.791	1.00
430_C	434_V	0.789	1.00
83_R	86_E	0.787	1.00
396_G	451_V	0.786	1.00
189_L	192_P	0.786	1.00
377_I	390_F	0.786	1.00
298_L	428_A	0.786	1.00
352_D	355_M	0.784	1.00
336_K	339_F	0.781	1.00
63_A	66_G	0.778	1.00
19_T	23_L	0.772	1.00
42_Y	46_G	0.771	1.00
51_L	54_L	0.769	1.00
132_P	142_A	0.768	1.00
201_H	226_D	0.765	1.00
51_L	55_S	0.763	1.00
204_A	229_Q	0.763	1.00
251_E	255_P	0.763	1.00
356_Q	433_I	0.762	1.00
250_H	360_N	0.761	1.00
142_A	148_V	0.759	1.00
160_D	164_R	0.759	1.00
86_E	89_N	0.759	1.00
40_I	44_K	0.758	1.00
385_T	458_P	0.758	1.00
325_A	329_R	0.758	1.00
132_P	135_V	0.757	1.00
141_G	144_I	0.756	1.00
106_Q	109_V	0.752	1.00
431_L	440_R	0.751	1.00
432_N	436_A	0.751	1.00
315_L	386_V	0.746	1.00
342_P	345_I	0.746	1.00
233_T	236_K	0.745	1.00
38_G	42_Y	0.745	1.00
87_H	90_S	0.745	1.00
82_L	86_E	0.743	1.00
399_D	403_Q	0.743	1.00
230_L	233_T	0.743	1.00
402_L	444_A	0.743	1.00
32_R	36_E	0.742	1.00
198_D	202_K	0.739	1.00
194_K	198_D	0.739	1.00
136_N	140_V	0.738	1.00
310_K	438_N	0.738	1.00
395_P	420_S	0.736	1.00
223_L	227_F	0.734	1.00
144_I	148_V	0.733	1.00
253_R	289_T	0.732	1.00
79_F	86_E	0.732	1.00
245_M	249_S	0.732	1.00
324_G	327_R	0.732	1.00
140_V	147_P	0.730	1.00
310_K	349_G	0.727	1.00
254_T	258_V	0.726	1.00
309_Q	350_D	0.725	1.00
274_T	277_T	0.725	1.00
211_R	231_A	0.725	1.00
42_Y	45_H	0.724	1.00
210_T	213_T	0.724	1.00
201_H	205_A	0.721	1.00
439_G	455_V	0.719	1.00
297_Q	356_Q	0.719	1.00
356_Q	359_N	0.718	1.00
279_A	282_Q	0.718	1.00
340_S	380_G	0.718	1.00
319_L	377_I	0.718	1.00
286_G	289_T	0.718	1.00
256_L	292_V	0.715	1.00
44_K	47_N	0.714	1.00
222_K	225_Q	0.712	1.00
25_I	29_W	0.710	1.00
39_F	42_Y	0.709	1.00
212_V	224_A	0.709	1.00
321_V	325_A	0.706	1.00
367_R	420_S	0.705	1.00
235_E	238_Q	0.705	1.00
141_G	147_P	0.704	1.00
199_G	202_K	0.701	1.00
161_K	164_R	0.700	1.00
262_E	281_L	0.700	1.00
46_G	50_R	0.699	1.00
344_S	381_Q	0.698	1.00
399_D	446_S	0.697	1.00
361_L	434_V	0.697	1.00
49_Q	52_Q	0.695	1.00
323_G	337_L	0.695	1.00
330_F	375_L	0.694	1.00
334_G	372_G	0.694	1.00
40_I	43_I	0.693	1.00
294_D	356_Q	0.693	1.00
216_S	220_L	0.693	1.00
398_S	412_T	0.692	1.00
397_V	445_H	0.692	1.00
162_Q	166_T	0.691	1.00
240_M	243_D	0.690	1.00
46_G	49_Q	0.690	1.00
162_Q	165_Q	0.689	1.00
280_S	283_A	0.689	1.00
297_Q	353_R	0.689	1.00
334_G	371_S	0.689	1.00
328_E	331_A	0.688	1.00
385_T	459_L	0.687	1.00
267_Q	278_V	0.685	1.00
136_N	141_G	0.685	1.00
353_R	357_L	0.684	1.00
43_I	47_N	0.683	1.00
248_I	295_L	0.683	1.00
313_V	351_R	0.681	1.00
262_E	284_E	0.675	1.00
369_T	372_G	0.675	1.00
392_D	395_P	0.675	1.00
347_V	350_D	0.673	1.00
191_A	195_R	0.671	1.00
223_L	226_D	0.671	1.00
168_W	172_A	0.670	1.00
192_P	197_V	0.670	1.00
308_Y	436_A	0.669	1.00
244_F	251_E	0.667	1.00
232_S	236_K	0.667	1.00
389_T	444_A	0.666	1.00
296_H	300_M	0.664	1.00
212_V	228_N	0.663	1.00
407_E	431_L	0.661	1.00
316_I	343_D	0.657	1.00
83_R	89_N	0.656	1.00
89_N	93_K	0.656	1.00
222_K	226_D	0.656	1.00
186_A	189_L	0.652	1.00
141_G	146_S	0.651	1.00
156_D	159_F	0.651	1.00
219_E	223_L	0.650	1.00
111_D	115_K	0.650	1.00
193_V	223_L	0.649	1.00
166_T	169_L	0.648	1.00
242_R	247_D	0.647	1.00
277_T	281_L	0.647	1.00
287_T	355_M	0.646	1.00
442_I	455_V	0.646	1.00
391_A	448_F	0.645	1.00
209_T	235_E	0.644	1.00
411_R	422_G	0.643	1.00
251_E	429_I	0.642	1.00
188_G	191_A	0.642	1.00
429_I	433_I	0.641	1.00
331_A	334_G	0.638	1.00
335_L	366_L	0.637	1.00
288_L	292_V	0.635	1.00
375_L	390_F	0.635	1.00
345_I	379_A	0.634	1.00
314_D	344_S	0.634	1.00
224_A	227_F	0.634	1.00
330_F	337_L	0.633	1.00
330_F	334_G	0.632	1.00
401_Q	414_G	0.631	1.00
324_G	328_E	0.629	1.00
41_D	44_K	0.628	1.00
195_R	198_D	0.628	1.00
157_I	161_K	0.627	1.00
80_Q	84_S	0.627	1.00
379_A	386_V	0.627	1.00
91_E	95_G	0.626	1.00
265_A	270_V	0.626	1.00
379_A	388_L	0.626	1.00
56_D	60_E	0.624	1.00
246_A	249_S	0.623	1.00
223_L	228_N	0.621	1.00
326_F	366_L	0.620	1.00
85_F	88_D	0.619	1.00
237_N	241_R	0.618	1.00
439_G	458_P	0.617	1.00
34_S	37_R	0.615	1.00
257_A	260_R	0.615	1.00
116_V	119_G	0.613	1.00
34_S	38_G	0.613	1.00
315_L	347_V	0.612	1.00
136_N	139_E	0.612	1.00
41_D	45_H	0.609	1.00
58_L	62_Y	0.609	1.00
242_R	302_D	0.608	1.00
90_S	93_K	0.608	1.00
247_D	251_E	0.608	1.00
9_T	194_K	0.608	1.00
172_A	176_L	0.606	1.00
52_Q	56_D	0.605	1.00
126_P	130_R	0.605	1.00
82_L	85_F	0.604	1.00
214_P	224_A	0.604	1.00
313_V	348_F	0.604	1.00
323_G	377_I	0.603	1.00
397_V	453_I	0.603	1.00
320_E	323_G	0.602	1.00
328_E	332_S	0.602	1.00
134_L	137_G	0.601	1.00
178_A	182_T	0.599	1.00
74_N	77_F	0.598	1.00
258_V	280_S	0.597	1.00
45_H	49_Q	0.597	1.00
323_G	326_F	0.596	1.00
15_A	19_T	0.595	1.00
402_L	453_I	0.595	1.00
26_S	30_A	0.594	1.00
317_P	351_R	0.594	1.00
362_L	375_L	0.594	1.00
402_L	451_V	0.593	1.00
405_L	428_A	0.591	1.00
284_E	325_A	0.590	1.00
353_R	437_H	0.590	1.00
367_R	422_G	0.588	1.00
192_P	200_T	0.588	1.00
333_R	371_S	0.586	1.00
37_R	40_I	0.586	1.00
365_S	390_F	0.586	1.00
140_V	143_V	0.584	1.00
210_T	214_P	0.584	1.00
141_G	148_V	0.584	1.00
335_L	339_F	0.583	1.00
405_L	410_Y	0.583	1.00
345_I	386_V	0.583	1.00
192_P	218_D	0.580	1.00
111_D	114_N	0.580	1.00
357_L	360_N	0.579	1.00
79_F	82_L	0.579	1.00
234_L	237_N	0.578	1.00
236_K	239_Q	0.578	1.00
302_D	408_R	0.578	1.00
204_A	233_T	0.576	1.00
103_W	106_Q	0.574	1.00
18_A	21_I	0.573	1.00
84_S	87_H	0.572	1.00
196_L	227_F	0.572	1.00
264_E	268_D	0.571	1.00
342_P	379_A	0.571	1.00
52_Q	55_S	0.570	1.00
196_L	224_A	0.570	1.00
198_D	201_H	0.569	1.00
110_V	117_L	0.569	1.00
356_Q	360_N	0.568	1.00
202_K	206_G	0.567	1.00
387_R	442_I	0.566	1.00
54_L	57_A	0.565	1.00
450_G	453_I	0.565	1.00
318_L	354_L	0.565	1.00
47_N	50_R	0.564	1.00
200_T	230_L	0.564	1.00
252_L	255_P	0.563	1.00
69_R	72_R	0.560	1.00
282_Q	285_V	0.560	1.00
326_F	329_R	0.560	1.00
217_E	220_L	0.560	1.00
193_V	220_L	0.560	1.00
109_V	114_N	0.559	1.00
218_D	222_K	0.559	1.00
278_V	282_Q	0.558	1.00
354_L	457_L	0.556	1.00
160_D	163_Q	0.555	1.00
109_V	113_N	0.554	1.00
192_P	216_S	0.554	1.00
233_T	237_N	0.553	1.00
403_Q	407_E	0.553	1.00
29_W	32_R	0.553	1.00
265_A	277_T	0.552	1.00
156_D	160_D	0.552	1.00
192_P	195_R	0.552	1.00
60_E	64_Q	0.550	1.00
262_E	266_I	0.550	1.00
273_F	277_T	0.548	1.00
60_E	63_A	0.547	1.00
37_R	41_D	0.547	1.00
132_P	137_G	0.545	1.00
225_Q	229_Q	0.544	1.00
428_A	432_N	0.543	1.00
108_W	114_N	0.543	1.00
430_C	433_I	0.541	1.00
406_F	409_F	0.540	1.00
102_G	106_Q	0.539	1.00
82_L	87_H	0.539	1.00
11_K	15_A	0.539	1.00
330_F	335_L	0.538	1.00
54_L	58_L	0.538	1.00
116_V	120_P	0.538	1.00
89_N	94_P	0.537	1.00
195_R	199_G	0.537	1.00
17_F	20_C	0.536	1.00
411_R	421_G	0.535	1.00
286_G	290_K	0.532	1.00
365_S	369_T	0.532	1.00
316_I	344_S	0.531	1.00
135_V	139_E	0.531	1.00
376_Q	379_A	0.530	1.00
262_E	285_V	0.530	1.00
333_R	369_T	0.529	1.00
317_P	320_E	0.528	1.00
135_V	138_A	0.528	1.00
57_A	60_E	0.527	1.00
16_I	182_T	0.527	1.00
294_D	352_D	0.526	1.00
202_K	205_A	0.526	1.00
216_S	219_E	0.525	1.00
187_R	194_K	0.524	1.00
381_Q	386_V	0.524	1.00
104_R	108_W	0.524	1.00
10_G	14_L	0.523	1.00
81_I	86_E	0.521	1.00
347_V	386_V	0.521	1.00
82_L	88_D	0.519	1.00
362_L	366_L	0.519	1.00
259_L	263_L	0.518	1.00
267_Q	270_V	0.518	1.00
166_T	170_I	0.516	1.00
277_T	280_S	0.516	1.00
398_S	402_L	0.515	1.00
68_W	72_R	0.515	1.00
101_H	104_R	0.513	1.00
49_Q	53_L	0.513	1.00
251_E	291_L	0.511	1.00
244_F	249_S	0.511	1.00
370_D	393_S	0.510	1.00
396_G	450_G	0.509	1.00
330_F	333_R	0.509	1.00
89_N	92_D	0.508	1.00
92_D	95_G	0.507	1.00
201_H	204_A	0.506	1.00
127_D	132_P	0.505	1.00
322_A	329_R	0.504	1.00
336_K	372_G	0.504	1.00
86_E	92_D	0.501	1.00
251_E	254_T	0.501	1.00
413_E	421_G	0.501	1.00
208_F	231_A	0.501	1.00
298_L	408_R	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.5803	100	0.322	Contact Map
4bixA	2	0.4882	100	0.364	Contact Map
4ctiA	2	0.4882	100	0.402	Contact Map
4q20A	2	0.4904	100	0.445	Contact Map
4mpcA	2	0.6424	100	0.462	Contact Map
3jz3A	2	0.3405	100	0.466	Contact Map
2c2aA	2	0.4946	100	0.47	Contact Map
4e01A	3	0.6103	100	0.471	Contact Map
2q8gA	2	0.6531	100	0.471	Contact Map
2e0aA	2	0.6552	100	0.477	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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