GREMLIN Database
BASS - Sensor protein BasS
UniProt: P30844 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11614
Length: 363 (290)
Sequences: 57518 (45799)
Seq/√Len: 2689.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
291_D295_G3.4821.00
290_E348_R3.3611.00
211_V249_G3.0811.00
326_S330_Q3.0361.00
337_F350_W2.9421.00
165_L179_L2.7891.00
301_C340_N2.6371.00
288_A348_R2.5971.00
249_G332_H2.5821.00
269_S292_E2.3441.00
278_K288_A2.3401.00
284_G352_R2.3241.00
288_A350_W2.2881.00
257_L329_T2.2771.00
169_A180_V2.2641.00
237_L276_M2.2521.00
297_D300_K2.2501.00
286_V352_R2.2431.00
338_L349_A2.2341.00
210_H248_Q2.2301.00
341_R345_S2.2081.00
325_V336_F2.2051.00
162_R184_D2.1971.00
281_E355_K2.1901.00
286_V350_W2.1611.00
280_Q286_V2.1511.00
276_M290_E2.1421.00
237_L274_N2.1391.00
239_P278_K2.1121.00
305_S336_F2.1051.00
274_N292_E2.0951.00
169_A177_A2.0911.00
301_C338_L2.0651.00
278_K290_E2.0481.00
329_T334_G2.0481.00
210_H246_T2.0141.00
339_Q348_R2.0091.00
280_Q288_A1.9771.00
339_Q350_W1.9451.00
296_I304_L1.9091.00
209_Q251_A1.9081.00
162_R183_L1.8991.00
220_P255_R1.8941.00
340_N347_T1.8761.00
303_E306_K1.8241.00
329_T351_V1.7981.00
212_K216_D1.7901.00
212_K215_E1.7701.00
335_Q352_R1.7671.00
235_T274_N1.7661.00
273_S292_E1.7601.00
300_K303_E1.7301.00
298_E301_C1.7241.00
257_L328_I1.7101.00
225_L259_R1.7031.00
239_P276_M1.7021.00
162_R187_M1.6831.00
249_G254_L1.6771.00
341_R344_T1.6601.00
263_E267_R1.6361.00
269_S273_S1.6231.00
296_I300_K1.6101.00
166_E180_V1.6001.00
118_A123_E1.5921.00
187_M191_S1.5861.00
229_L266_H1.5751.00
303_E309_V1.5651.00
120_L123_E1.5571.00
104_A109_N1.5511.00
330_Q335_Q1.5471.00
257_L325_V1.5461.00
300_K309_V1.5391.00
296_I347_T1.5381.00
208_Y248_Q1.5311.00
153_E256_M1.5261.00
161_V183_L1.5211.00
337_F352_R1.4881.00
328_I332_H1.4771.00
145_L149_D1.4461.00
141_D145_L1.4431.00
165_L180_V1.4321.00
305_S338_L1.4261.00
300_K311_M1.4221.00
258_L287_M1.4131.00
132_L136_L1.3771.00
260_N325_V1.3591.00
119_T123_E1.3561.00
287_M351_V1.3471.00
253_L256_M1.3391.00
143_E147_T1.3161.00
276_M292_E1.3111.00
291_D346_G1.3051.00
140_L143_E1.2861.00
212_K244_D1.2851.00
250_D253_L1.2841.00
340_N344_T1.2831.00
130_N133_V1.2771.00
161_V179_L1.2661.00
133_V136_L1.2641.00
226_S230_D1.2331.00
180_V184_D1.2321.00
84_C88_V1.2291.00
340_N345_S1.2181.00
215_E219_L1.2071.00
149_D307_A1.2031.00
257_L351_V1.1981.00
168_L176_V1.1981.00
220_P251_A1.1951.00
122_I126_V1.1821.00
285_A355_K1.1711.00
297_D342_Q1.1671.00
224_E255_R1.1631.00
329_T336_F1.1451.00
212_K246_T1.1451.00
115_I118_A1.1341.00
165_L169_A1.1301.00
165_L183_L1.1271.00
215_E279_L1.1171.00
305_S349_A1.1151.00
162_R180_V1.1091.00
301_C305_S1.1031.00
334_G353_L1.0871.00
139_T143_E1.0831.00
105_R133_V1.0781.00
306_K309_V1.0731.00
160_G164_H1.0691.00
137_T141_D1.0671.00
327_R330_Q1.0661.00
304_L338_L1.0621.00
253_L328_I1.0591.00
164_H178_P1.0571.00
251_A255_R1.0571.00
160_G182_R1.0571.00
253_L331_L1.0531.00
102_L106_T1.0421.00
206_G250_D1.0411.00
102_L105_R1.0261.00
310_R315_Y1.0221.00
254_L332_H1.0211.00
260_N263_E1.0191.00
219_L238_L1.0181.00
208_Y332_H1.0051.00
188_E252_T1.0041.00
338_L347_T1.0011.00
222_Y238_L0.9971.00
217_V221_S0.9931.00
342_Q345_S0.9931.00
138_S142_N0.9931.00
146_F150_V0.9901.00
228_M231_Q0.9801.00
126_V130_N0.9791.00
268_Y310_R0.9751.00
221_S259_R0.9751.00
145_L307_A0.9721.00
269_S275_I0.9681.00
115_I119_T0.9661.00
118_A122_I0.9661.00
119_T122_I0.9631.00
290_E341_R0.9581.00
291_D347_T0.9581.00
99_Q103_E0.9561.00
334_G351_V0.9461.00
217_V249_G0.9451.00
245_I285_A0.9411.00
81_L85_Y0.9401.00
112_P115_I0.9391.00
67_A71_V0.9351.00
118_A126_V0.9331.00
310_R317_G0.9321.00
241_S244_D0.9301.00
305_S326_S0.9241.00
215_E244_D0.9211.00
122_I125_V0.9191.00
177_A181_A0.9191.00
114_A118_A0.9181.00
163_L167_L0.9171.00
221_S225_L0.9161.00
221_S255_R0.9111.00
88_V92_T0.9071.00
99_Q124_A0.9061.00
218_I279_L0.8991.00
284_G335_Q0.8871.00
165_L176_V0.8871.00
182_R185_Q0.8721.00
207_N250_D0.8721.00
191_S195_Q0.8691.00
131_D135_R0.8691.00
123_E126_V0.8651.00
211_V217_V0.8621.00
228_M263_E0.8581.00
296_I302_G0.8571.00
295_G347_T0.8551.00
91_I94_P0.8541.00
155_R191_S0.8501.00
181_A220_P0.8451.00
241_S279_L0.8421.00
268_Y294_P0.8421.00
238_L241_S0.8321.00
178_P182_R0.8251.00
329_T353_L0.8231.00
258_L289_V0.8201.00
140_L144_R0.8201.00
304_L349_A0.8161.00
192_Q253_L0.8161.00
129_L132_L0.8141.00
258_L262_V0.8091.00
298_E340_N0.8091.00
89_R93_R0.8071.00
265_A275_I0.8051.00
179_L183_L0.8021.00
162_R166_E0.7981.00
158_L190_V0.7981.00
252_T255_R0.7961.00
123_E127_S0.7941.00
222_Y236_L0.7941.00
225_L262_V0.7871.00
195_Q256_M0.7861.00
208_Y249_G0.7841.00
261_L349_A0.7831.00
327_R331_L0.7801.00
224_E259_R0.7761.00
216_D220_P0.7761.00
211_V251_A0.7741.00
196_L323_S0.7731.00
296_I338_L0.7661.00
212_K245_I0.7661.00
82_F86_Q0.7661.00
259_R263_E0.7651.00
296_I301_C0.7651.00
154_L186_M0.7651.00
270_P273_S0.7611.00
183_L187_M0.7541.00
128_A131_D0.7531.00
178_P181_A0.7471.00
245_I281_E0.7421.00
219_L223_D0.7401.00
167_L171_T0.7341.00
160_G163_L0.7331.00
144_R200_G0.7331.00
129_L133_V0.7321.00
218_I258_L0.7311.00
213_L287_M0.7301.00
125_V129_L0.7281.00
208_Y333_H0.7271.00
153_E157_P0.7251.00
261_L336_F0.7211.00
130_N134_S0.7211.00
96_A99_Q0.7191.00
288_A339_Q0.7171.00
255_R259_R0.7161.00
99_Q128_A0.7141.00
320_L324_I0.7131.00
119_T126_V0.7081.00
296_I340_N0.7051.00
192_Q256_M0.7051.00
156_T160_G0.7051.00
225_L263_E0.7041.00
337_F351_V0.7031.00
229_L275_I0.7011.00
261_L325_V0.7011.00
256_M259_R0.7011.00
86_Q90_R0.7001.00
261_L351_V0.7001.00
94_P98_L0.7001.00
215_E243_A0.6981.00
118_A125_V0.6981.00
206_G253_L0.6951.00
256_M328_I0.6901.00
85_Y89_R0.6891.00
103_E124_A0.6821.00
169_A176_V0.6821.00
206_G331_L0.6811.00
222_Y226_S0.6801.00
138_S141_D0.6801.00
242_A245_I0.6801.00
325_V329_T0.6791.00
63_R67_A0.6781.00
229_L236_L0.6771.00
233_Q272_G0.6771.00
257_L332_H0.6771.00
145_L327_R0.6751.00
185_Q255_R0.6751.00
297_D311_M0.6711.00
172_H175_D0.6691.00
88_V91_I0.6681.00
334_G354_K0.6671.00
283_D355_K0.6661.00
177_A180_V0.6591.00
223_D226_S0.6591.00
267_R315_Y0.6591.00
232_R266_H0.6561.00
184_D187_M0.6551.00
298_E341_R0.6511.00
106_T109_N0.6491.00
230_D233_Q0.6491.00
182_R224_E0.6491.00
141_D144_R0.6481.00
188_E192_Q0.6471.00
301_C339_Q0.6461.00
113_I133_V0.6451.00
213_L285_A0.6421.00
66_V70_I0.6411.00
211_V248_Q0.6411.00
221_S262_V0.6401.00
301_C349_A0.6371.00
227_T230_D0.6371.00
164_H182_R0.6361.00
142_N145_L0.6351.00
112_P118_A0.6341.00
102_L128_A0.6331.00
215_E241_S0.6331.00
291_D294_P0.6321.00
277_I289_V0.6311.00
103_E107_A0.6311.00
225_L266_H0.6281.00
137_T140_L0.6281.00
286_V337_F0.6271.00
326_S335_Q0.6261.00
149_D153_E0.6251.00
290_E344_T0.6231.00
229_L234_Q0.6221.00
298_E302_G0.6211.00
90_R93_R0.6191.00
116_H123_E0.6181.00
195_Q253_L0.6181.00
159_A163_L0.6181.00
152_H260_N0.6171.00
194_L197_A0.6161.00
147_T150_V0.6151.00
218_I277_I0.6121.00
243_A281_E0.6121.00
102_L129_L0.6121.00
147_T151_A0.6081.00
98_L102_L0.6081.00
234_Q238_L0.6081.00
262_V275_I0.6051.00
124_A127_S0.6051.00
296_I349_A0.6031.00
234_Q266_H0.5991.00
150_V193_L0.5991.00
103_E128_A0.5961.00
139_T142_N0.5951.00
155_R187_M0.5951.00
233_Q271_Q0.5941.00
116_H120_L0.5931.00
68_S71_V0.5921.00
216_D251_A0.5901.00
295_G346_G0.5881.00
114_A126_V0.5881.00
106_T131_D0.5871.00
70_I74_V0.5861.00
112_P119_T0.5841.00
234_Q275_I0.5831.00
105_R108_D0.5811.00
267_R317_G0.5811.00
221_S224_E0.5811.00
234_Q269_S0.5791.00
217_V254_L0.5781.00
307_A327_R0.5741.00
126_V129_L0.5741.00
105_R132_L0.5731.00
160_G178_P0.5711.00
113_I134_S0.5701.00
200_G327_R0.5671.00
113_I118_A0.5651.00
294_P315_Y0.5631.00
133_V137_T0.5601.00
119_T125_V0.5581.00
125_V128_A0.5581.00
67_A70_I0.5571.00
114_A130_N0.5561.00
222_Y277_I0.5561.00
310_R316_G0.5551.00
228_M232_R0.5551.00
104_A108_D0.5541.00
239_P280_Q0.5531.00
154_L190_V0.5531.00
262_V277_I0.5521.00
261_L329_T0.5511.00
176_V180_V0.5501.00
275_I289_V0.5501.00
229_L232_R0.5491.00
241_S280_Q0.5481.00
153_E260_N0.5471.00
164_H179_L0.5451.00
245_I279_L0.5451.00
232_R271_Q0.5431.00
100_K104_A0.5431.00
109_N112_P0.5431.00
63_R66_V0.5421.00
223_D227_T0.5421.00
97_E101_E0.5411.00
194_L198_R0.5401.00
62_I66_V0.5401.00
336_F349_A0.5401.00
153_E324_I0.5391.00
279_L285_A0.5381.00
74_V78_S0.5361.00
269_S272_G0.5361.00
200_G307_A0.5361.00
146_F153_E0.5341.00
227_T231_Q0.5331.00
265_A289_V0.5321.00
304_L323_S0.5321.00
166_E170_K0.5311.00
101_E104_A0.5301.00
262_V266_H0.5301.00
124_A128_A0.5281.00
300_K312_D0.5271.00
297_D301_C0.5261.00
247_V285_A0.5251.00
135_R138_S0.5231.00
235_T238_L0.5191.00
247_V353_L0.5181.00
120_L124_A0.5161.00
306_K326_S0.5161.00
241_S245_I0.5151.00
99_Q102_L0.5151.00
101_E114_A0.5141.00
304_L309_V0.5111.00
211_V254_L0.5111.00
346_G349_A0.5111.00
131_D134_S0.5091.00
215_E245_I0.5091.00
216_D219_L0.5051.00
110_L133_V0.5051.00
253_L332_H0.5041.00
132_L135_R0.5041.00
340_N346_G0.5041.00
152_H156_T0.5031.00
64_E68_S0.5021.00
264_N268_Y0.5011.00
284_G355_K0.5011.00
71_V75_F0.5001.00
186_M190_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4i5sA 2 0.73 100 0.312 Contact Map
4bixA 2 0.6226 100 0.348 Contact Map
4ctiA 2 0.6253 100 0.367 Contact Map
4q20A 2 0.6226 100 0.413 Contact Map
3jz3A 2 0.4353 100 0.423 Contact Map
4mpcA 2 0.8154 100 0.433 Contact Map
2q8gA 2 0.8154 100 0.442 Contact Map
4gczA 2 0.8981 100 0.444 Contact Map
2c2aA 2 0.6253 100 0.448 Contact Map
2e0aA 2 0.8375 100 0.454 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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