SDHM - ECOLI - GREMLIN Contacts

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SDHM - L-serine dehydratase 2

UniProt:	P30744	Sequences: MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPSFIQDVNTHGRLMLANGQHEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQDSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRGGIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVACD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11623
Length:	455 (449)
Sequences:	1755 (992)
Seq/√Len:	46.8

ECOLI - SDHM TDCG SDHL
BACSU - SDHAA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
210_A	313_A	4.539	1.00
189_S	356_E	4.159	1.00
373_M	424_V	4.145	1.00
264_I	404_V	4.000	1.00
220_I	298_A	3.938	1.00
197_L	202_K	3.633	1.00
265_N	405_N	3.561	1.00
426_E	430_E	3.551	1.00
128_R	142_T	3.488	1.00
314_R	356_E	3.202	1.00
71_A	86_F	3.197	1.00
180_H	184_T	3.106	1.00
197_L	205_L	3.067	1.00
300_Y	311_S	3.041	1.00
355_A	360_A	3.003	1.00
44_R	112_C	2.989	1.00
182_Q	363_A	2.939	1.00
194_K	197_L	2.842	1.00
355_A	407_A	2.821	1.00
180_H	191_L	2.790	1.00
201_S	204_E	2.726	1.00
325_L	425_I	2.717	1.00
326_Y	348_S	2.714	1.00
91_N	109_V	2.702	1.00
122_L	144_Y	2.674	1.00
337_V	341_G	2.656	1.00
193_M	206_E	2.590	1.00
244_R	248_V	2.570	1.00
209_L	316_L	2.541	1.00
94_G	108_P	2.503	1.00
67_I	90_V	2.487	1.00
347_C	372_A	2.479	1.00
34_I	102_Q	2.477	1.00
241_A	245_R	2.470	1.00
179_K	183_E	2.338	1.00
95_R	104_E	2.276	1.00
326_Y	345_V	2.253	1.00
108_P	111_Q	2.243	1.00
44_R	132_L	2.231	1.00
210_A	309_A	2.227	1.00
74_L	77_T	2.212	1.00
130_T	140_S	2.182	1.00
206_E	313_A	2.149	1.00
10_I	211_N	2.124	1.00
71_A	90_V	2.111	1.00
227_E	245_R	2.111	1.00
189_S	314_R	2.100	1.00
4_V	320_S	2.092	1.00
9_K	24_K	2.078	1.00
130_T	137_V	2.078	1.00
181_C	362_P	2.073	1.00
48_D	116_H	2.032	0.99
202_K	206_E	2.010	0.99
322_I	352_A	1.977	0.99
133_A	136_K	1.977	0.99
4_V	209_L	1.946	0.99
120_L	126_G	1.938	0.99
233_K	387_Q	1.902	0.99
49_V	66_I	1.884	0.99
229_V	235_R	1.880	0.99
28_Q	151_I	1.880	0.99
48_D	130_T	1.865	0.99
27_K	31_D	1.864	0.99
67_I	113_M	1.855	0.99
356_E	365_V	1.840	0.99
8_F	319_A	1.838	0.99
32_D	139_Y	1.811	0.99
9_K	76_D	1.799	0.99
309_A	313_A	1.795	0.99
206_E	210_A	1.790	0.99
206_E	309_A	1.785	0.99
45_V	98_L	1.776	0.99
5_F	208_H	1.755	0.98
43_T	133_A	1.727	0.98
89_D	93_H	1.726	0.98
362_P	365_V	1.713	0.98
200_H	204_E	1.711	0.98
419_V	451_I	1.692	0.98
186_L	191_L	1.679	0.98
38_L	41_D	1.670	0.98
190_G	194_K	1.662	0.98
169_Y	194_K	1.662	0.98
326_Y	373_M	1.660	0.98
347_C	376_N	1.649	0.98
203_E	207_Q	1.649	0.98
307_V	311_S	1.640	0.98
434_D	439_Y	1.634	0.98
334_G	397_A	1.630	0.97
177_L	191_L	1.591	0.97
360_A	411_L	1.586	0.97
137_V	140_S	1.572	0.97
345_V	399_A	1.566	0.97
63_D	115_F	1.564	0.97
141_Q	153_D	1.562	0.97
421_L	425_I	1.551	0.97
200_H	208_H	1.542	0.96
426_E	429_Y	1.541	0.96
81_D	222_R	1.536	0.96
176_D	179_K	1.535	0.96
217_R	298_A	1.521	0.96
361_S	364_Q	1.517	0.96
181_C	191_L	1.506	0.96
33_L	131_A	1.506	0.96
5_F	205_L	1.504	0.96
430_E	433_K	1.504	0.96
192_M	324_S	1.503	0.96
40_K	103_H	1.502	0.96
172_S	328_M	1.498	0.96
267_F	303_F	1.492	0.96
310_N	314_R	1.489	0.96
367_I	413_R	1.488	0.96
32_D	141_Q	1.487	0.96
169_Y	184_T	1.486	0.96
201_S	205_L	1.481	0.96
256_D	408_R	1.478	0.95
237_P	416_E	1.477	0.95
122_L	157_F	1.474	0.95
318_V	356_E	1.473	0.95
193_M	205_L	1.450	0.95
348_S	373_M	1.449	0.95
43_T	134_G	1.438	0.95
39_L	103_H	1.435	0.95
218_G	222_R	1.427	0.94
308_N	311_S	1.424	0.94
206_E	310_N	1.413	0.94
193_M	202_K	1.410	0.94
67_I	71_A	1.403	0.94
73_N	86_F	1.397	0.94
217_R	220_I	1.389	0.94
331_S	341_G	1.385	0.94
311_S	357_L	1.381	0.93
142_T	154_E	1.381	0.93
376_N	379_L	1.381	0.93
429_Y	433_K	1.362	0.93
119_N	124_E	1.350	0.93
213_W	312_L	1.345	0.93
108_P	112_C	1.343	0.92
172_S	176_D	1.338	0.92
10_I	215_V	1.336	0.92
180_H	183_E	1.332	0.92
390_V	418_R	1.324	0.92
300_Y	307_V	1.321	0.92
222_R	274_E	1.319	0.92
27_K	74_L	1.310	0.92
171_Y	192_M	1.305	0.91
178_Q	362_P	1.295	0.91
66_I	127_M	1.284	0.91
67_I	109_V	1.284	0.91
224_I	266_M	1.281	0.91
132_L	137_V	1.279	0.91
398_I	405_N	1.277	0.90
211_N	215_V	1.268	0.90
95_R	106_E	1.264	0.90
413_R	417_P	1.251	0.90
88_Q	92_T	1.251	0.90
245_R	248_V	1.247	0.89
26_G	129_I	1.242	0.89
187_S	190_G	1.241	0.89
322_I	353_G	1.237	0.89
73_N	82_S	1.233	0.89
292_I	334_G	1.230	0.89
200_H	205_L	1.228	0.89
46_V	130_T	1.227	0.89
97_M	104_E	1.222	0.88
221_E	225_S	1.220	0.88
34_I	99_A	1.214	0.88
367_I	417_P	1.212	0.88
246_M	412_R	1.206	0.88
401_V	405_N	1.205	0.88
426_E	450_K	1.204	0.88
42_V	138_V	1.186	0.87
202_K	205_L	1.177	0.86
265_N	398_I	1.169	0.86
208_H	212_V	1.166	0.86
173_S	176_D	1.163	0.86
214_E	218_G	1.156	0.85
366_C	417_P	1.150	0.85
64_I	84_P	1.142	0.85
86_F	90_V	1.141	0.85
122_L	154_E	1.139	0.85
184_T	191_L	1.136	0.84
345_V	348_S	1.136	0.84
310_N	313_A	1.123	0.84
170_P	180_H	1.122	0.84
292_I	379_L	1.122	0.84
58_K	63_D	1.116	0.83
50_Y	126_G	1.105	0.83
367_I	415_S	1.103	0.83
46_V	114_N	1.102	0.83
58_K	115_F	1.101	0.82
99_A	102_Q	1.093	0.82
42_V	131_A	1.086	0.82
437_A	444_R	1.077	0.81
36_R	139_Y	1.076	0.81
267_F	302_K	1.075	0.81
219_G	281_V	1.075	0.81
126_G	129_I	1.070	0.81
186_L	194_K	1.068	0.80
334_G	343_V	1.053	0.80
261_V	401_V	1.045	0.79
292_I	400_A	1.045	0.79
197_L	201_S	1.044	0.79
133_A	138_V	1.042	0.79
331_S	337_V	1.041	0.79
5_F	212_V	1.041	0.79
96_L	107_F	1.038	0.79
190_G	314_R	1.037	0.78
262_D	408_R	1.031	0.78
82_S	86_F	1.022	0.77
298_A	302_K	1.017	0.77
28_Q	156_H	1.014	0.77
217_R	221_E	1.008	0.76
360_A	364_Q	1.002	0.76
39_L	98_L	1.002	0.76
427_T	447_L	1.002	0.76
423_K	452_V	1.001	0.76
384_V	419_V	1.000	0.76
187_S	356_E	0.998	0.76
226_T	241_A	0.996	0.76
94_G	109_V	0.992	0.75
345_V	372_A	0.992	0.75
175_A	179_K	0.992	0.75
10_I	212_V	0.992	0.75
76_D	211_N	0.984	0.75
127_M	451_I	0.981	0.75
264_I	401_V	0.979	0.74
347_C	399_A	0.978	0.74
54_S	62_T	0.976	0.74
170_P	195_N	0.974	0.74
31_D	99_A	0.969	0.74
153_D	157_F	0.968	0.74
250_Q	412_R	0.965	0.73
341_G	405_N	0.964	0.73
326_Y	353_G	0.964	0.73
269_L	397_A	0.962	0.73
318_V	322_I	0.961	0.73
427_T	434_D	0.958	0.73
68_M	83_I	0.950	0.72
79_D	82_S	0.948	0.72
24_K	76_D	0.946	0.72
198_A	205_L	0.936	0.71
171_Y	321_A	0.936	0.71
214_E	309_A	0.933	0.71
324_S	372_A	0.932	0.71
30_T	99_A	0.927	0.70
55_L	444_R	0.924	0.70
301_D	312_L	0.924	0.70
2_I	6_D	0.923	0.70
247_L	263_W	0.923	0.70
109_V	113_M	0.923	0.70
41_D	133_A	0.914	0.69
47_V	129_I	0.912	0.69
55_L	345_V	0.911	0.69
210_A	310_N	0.910	0.69
262_D	412_R	0.908	0.69
331_S	432_G	0.905	0.68
251_D	254_T	0.905	0.68
170_P	173_S	0.905	0.68
263_W	303_F	0.903	0.68
46_V	132_L	0.900	0.68
97_M	102_Q	0.900	0.68
20_V	24_K	0.899	0.68
213_W	217_R	0.893	0.67
188_L	318_V	0.893	0.67
265_N	397_A	0.892	0.67
40_K	102_Q	0.892	0.67
38_L	42_V	0.892	0.67
62_T	168_P	0.892	0.67
153_D	156_H	0.890	0.67
116_H	119_N	0.889	0.67
193_M	197_L	0.887	0.67
86_F	89_D	0.885	0.67
128_R	140_S	0.885	0.67
42_V	98_L	0.883	0.66
430_E	450_K	0.882	0.66
222_R	226_T	0.880	0.66
324_S	328_M	0.880	0.66
94_G	106_E	0.879	0.66
366_C	415_S	0.877	0.66
168_P	198_A	0.868	0.65
337_V	432_G	0.864	0.65
311_S	314_R	0.861	0.64
176_D	183_E	0.859	0.64
141_Q	155_E	0.856	0.64
39_L	42_V	0.856	0.64
229_V	233_K	0.853	0.64
66_I	113_M	0.849	0.63
209_L	320_S	0.846	0.63
39_L	99_A	0.845	0.63
168_P	195_N	0.844	0.63
299_Y	303_F	0.844	0.63
180_H	185_G	0.838	0.62
37_N	40_K	0.831	0.62
345_V	373_M	0.827	0.61
379_L	398_I	0.820	0.61
64_I	443_S	0.819	0.61
211_N	214_E	0.817	0.60
208_H	211_N	0.810	0.60
177_L	321_A	0.807	0.59
62_T	115_F	0.806	0.59
199_L	205_L	0.803	0.59
292_I	343_V	0.799	0.59
87_I	91_N	0.792	0.58
9_K	20_V	0.792	0.58
82_S	89_D	0.792	0.58
224_I	244_R	0.791	0.58
31_D	34_I	0.791	0.58
71_A	97_M	0.791	0.58
251_D	259_A	0.786	0.57
334_G	337_V	0.785	0.57
28_Q	32_D	0.784	0.57
12_I	68_M	0.784	0.57
48_D	114_N	0.782	0.57
13_G	17_S	0.780	0.57
89_D	92_T	0.779	0.57
300_Y	304_I	0.769	0.56
169_Y	180_H	0.769	0.56
348_S	424_V	0.762	0.55
189_S	318_V	0.761	0.55
221_E	298_A	0.761	0.55
81_D	84_P	0.759	0.55
207_Q	211_N	0.753	0.54
167_V	199_L	0.745	0.53
227_E	241_A	0.741	0.53
49_V	113_M	0.740	0.53
301_D	307_V	0.739	0.53
252_K	255_T	0.737	0.53
150_F	327_K	0.737	0.53
120_L	142_T	0.736	0.52
187_S	314_R	0.735	0.52
256_D	264_I	0.732	0.52
331_S	334_G	0.732	0.52
38_L	138_V	0.732	0.52
56_T	59_G	0.730	0.52
300_Y	357_L	0.728	0.52
2_I	328_M	0.726	0.52
409_M	418_R	0.723	0.51
426_E	433_K	0.722	0.51
190_G	249_S	0.721	0.51
61_H	443_S	0.720	0.51
257_P	262_D	0.719	0.51
84_P	87_I	0.718	0.51
66_I	124_E	0.715	0.50
191_L	361_S	0.714	0.50
366_C	413_R	0.713	0.50
256_D	259_A	0.710	0.50
215_V	219_G	0.708	0.50
221_E	244_R	0.707	0.50
78_V	83_I	0.706	0.50
193_M	313_A	0.706	0.50
193_M	310_N	0.705	0.49
82_S	85_S	0.703	0.49
48_D	64_I	0.703	0.49
96_L	105_V	0.700	0.49
45_V	122_L	0.699	0.49
168_P	199_L	0.698	0.49
306_E	311_S	0.698	0.49
364_Q	371_I	0.696	0.49
13_G	18_H	0.694	0.48
265_N	401_V	0.693	0.48
124_E	144_Y	0.693	0.48
242_A	246_M	0.690	0.48
258_M	408_R	0.690	0.48
376_N	398_I	0.689	0.48
293_I	319_A	0.688	0.48
325_L	329_N	0.687	0.48
355_A	409_M	0.687	0.48
58_K	61_H	0.686	0.48
120_L	144_Y	0.686	0.48
87_I	109_V	0.685	0.47
372_A	409_M	0.685	0.47
169_Y	195_N	0.684	0.47
64_I	334_G	0.683	0.47
31_D	35_A	0.682	0.47
385_A	390_V	0.681	0.47
345_V	424_V	0.681	0.47
63_D	113_M	0.678	0.47
220_I	301_D	0.678	0.47
50_Y	116_H	0.675	0.46
192_M	321_A	0.671	0.46
84_P	88_Q	0.671	0.46
71_A	89_D	0.670	0.46
427_T	450_K	0.670	0.46
117_A	436_N	0.669	0.46
345_V	429_Y	0.666	0.46
226_T	277_A	0.664	0.45
267_F	329_N	0.663	0.45
356_E	362_P	0.659	0.45
304_I	311_S	0.658	0.45
153_D	376_N	0.658	0.45
243_L	267_F	0.658	0.45
318_V	352_A	0.655	0.44
348_S	376_N	0.655	0.44
186_L	363_A	0.655	0.44
68_M	84_P	0.655	0.44
88_Q	91_N	0.655	0.44
341_G	432_G	0.654	0.44
184_T	194_K	0.653	0.44
252_K	302_K	0.653	0.44
26_G	66_I	0.652	0.44
221_E	302_K	0.652	0.44
221_E	224_I	0.652	0.44
194_K	225_S	0.652	0.44
292_I	397_A	0.650	0.44
317_L	397_A	0.650	0.44
267_F	357_L	0.649	0.44
364_Q	411_L	0.648	0.44
320_S	324_S	0.646	0.44
93_H	106_E	0.643	0.43
301_D	311_S	0.643	0.43
141_Q	151_I	0.643	0.43
420_C	424_V	0.643	0.43
186_L	242_A	0.642	0.43
67_I	86_F	0.641	0.43
45_V	103_H	0.639	0.43
132_L	136_K	0.639	0.43
129_I	142_T	0.638	0.43
261_V	398_I	0.638	0.43
142_T	174_A	0.638	0.43
237_P	414_T	0.637	0.43
258_M	329_N	0.636	0.43
435_M	440_R	0.636	0.43
264_I	405_N	0.636	0.43
39_L	102_Q	0.635	0.43
89_D	137_V	0.634	0.42
63_D	405_N	0.633	0.42
93_H	104_E	0.632	0.42
204_E	208_H	0.632	0.42
58_K	423_K	0.631	0.42
367_I	427_T	0.628	0.42
2_I	205_L	0.627	0.42
173_S	329_N	0.626	0.42
110_D	114_N	0.625	0.42
329_N	334_G	0.625	0.42
44_R	111_Q	0.624	0.41
304_I	358_L	0.623	0.41
152_V	157_F	0.623	0.41
262_D	376_N	0.623	0.41
46_V	50_Y	0.623	0.41
13_G	16_S	0.622	0.41
113_M	279_G	0.622	0.41
80_I	222_R	0.620	0.41
77_T	215_V	0.619	0.41
14_P	17_S	0.619	0.41
326_Y	425_I	0.619	0.41
14_P	18_H	0.618	0.41
201_S	207_Q	0.618	0.41
24_K	28_Q	0.618	0.41
337_V	405_N	0.617	0.41
77_T	80_I	0.615	0.41
224_I	443_S	0.615	0.41
144_Y	157_F	0.615	0.41
357_L	362_P	0.614	0.41
304_I	307_V	0.614	0.41
266_M	269_L	0.614	0.41
7_I	157_F	0.614	0.41
28_Q	143_Y	0.613	0.40
326_Y	424_V	0.612	0.40
237_P	242_A	0.611	0.40
214_E	237_P	0.610	0.40
418_R	423_K	0.610	0.40
98_L	105_V	0.610	0.40
45_V	102_Q	0.609	0.40
73_N	113_M	0.609	0.40
26_G	47_V	0.607	0.40
208_H	290_C	0.606	0.40
12_I	83_I	0.605	0.40
201_S	208_H	0.605	0.40
361_S	414_T	0.604	0.40
252_K	259_A	0.604	0.40
46_V	140_S	0.603	0.39
133_A	137_V	0.603	0.39
116_H	355_A	0.602	0.39
26_G	269_L	0.602	0.39
217_R	302_K	0.601	0.39
315_Y	357_L	0.601	0.39
193_M	314_R	0.601	0.39
322_I	355_A	0.601	0.39
103_H	106_E	0.601	0.39
353_G	365_V	0.600	0.39
122_L	409_M	0.600	0.39
405_N	437_A	0.600	0.39
167_V	198_A	0.597	0.39
10_I	281_V	0.597	0.39
427_T	439_Y	0.595	0.39
265_N	341_G	0.594	0.39
94_G	110_D	0.594	0.39
13_G	19_T	0.593	0.39
188_L	356_E	0.593	0.39
337_V	397_A	0.591	0.38
325_L	409_M	0.590	0.38
266_M	387_Q	0.589	0.38
95_R	144_Y	0.588	0.38
9_K	241_A	0.587	0.38
363_A	416_E	0.586	0.38
326_Y	352_A	0.585	0.38
10_I	218_G	0.585	0.38
336_E	346_A	0.584	0.38
256_D	303_F	0.583	0.38
43_T	186_L	0.583	0.38
233_K	390_V	0.583	0.38
158_G	161_D	0.582	0.37
35_A	229_V	0.580	0.37
343_V	346_A	0.580	0.37
257_P	408_R	0.579	0.37
29_F	131_A	0.578	0.37
68_M	402_K	0.578	0.37
24_K	259_A	0.578	0.37
243_L	401_V	0.578	0.37
409_M	425_I	0.577	0.37
50_Y	373_M	0.576	0.37
256_D	304_I	0.576	0.37
105_V	112_C	0.576	0.37
85_S	89_D	0.576	0.37
54_S	63_D	0.576	0.37
300_Y	354_L	0.575	0.37
43_T	136_K	0.575	0.37
23_M	336_E	0.574	0.37
261_V	345_V	0.574	0.37
213_W	301_D	0.573	0.37
2_I	324_S	0.573	0.37
146_I	242_A	0.573	0.37
169_Y	191_L	0.572	0.37
83_I	87_I	0.572	0.37
241_A	244_R	0.572	0.37
420_C	423_K	0.572	0.37
186_L	190_G	0.572	0.37
287_N	327_K	0.571	0.36
301_D	308_N	0.571	0.36
92_T	114_N	0.571	0.36
347_C	379_L	0.571	0.36
92_T	182_Q	0.570	0.36
192_M	400_A	0.570	0.36
219_G	272_N	0.567	0.36
434_D	438_K	0.567	0.36
348_S	408_R	0.566	0.36
124_E	440_R	0.566	0.36
334_G	432_G	0.566	0.36
175_A	225_S	0.565	0.36
419_V	427_T	0.565	0.36
31_D	211_N	0.565	0.36
37_N	139_Y	0.564	0.36
47_V	67_I	0.563	0.36
91_N	113_M	0.562	0.36
175_A	180_H	0.561	0.36
181_C	405_N	0.561	0.36
222_R	279_G	0.560	0.35
87_I	155_E	0.558	0.35
32_D	36_R	0.558	0.35
78_V	154_E	0.557	0.35
14_P	19_T	0.557	0.35
300_Y	347_C	0.556	0.35
35_A	84_P	0.555	0.35
191_L	197_L	0.555	0.35
24_K	158_G	0.554	0.35
50_Y	120_L	0.554	0.35
162_S	166_E	0.554	0.35
30_T	38_L	0.551	0.35
126_G	144_Y	0.550	0.35
158_G	162_S	0.549	0.34
143_Y	401_V	0.549	0.34
30_T	98_L	0.548	0.34
335_A	441_E	0.548	0.34
54_S	66_I	0.547	0.34
171_Y	324_S	0.547	0.34
47_V	307_V	0.546	0.34
146_I	379_L	0.544	0.34
98_L	102_Q	0.544	0.34
236_V	279_G	0.544	0.34
207_Q	210_A	0.544	0.34
337_V	429_Y	0.544	0.34
334_G	384_V	0.543	0.34
258_M	262_D	0.543	0.34
33_L	42_V	0.542	0.34
43_T	110_D	0.542	0.34
45_V	96_L	0.542	0.34
345_V	405_N	0.541	0.34
187_S	191_L	0.541	0.34
26_G	105_V	0.541	0.34
46_V	112_C	0.539	0.34
143_Y	402_K	0.539	0.34
41_D	183_E	0.539	0.34
415_S	440_R	0.538	0.33
376_N	402_K	0.538	0.33
20_V	292_I	0.538	0.33
111_Q	175_A	0.538	0.33
124_E	409_M	0.538	0.33
104_E	159_Q	0.538	0.33
55_L	399_A	0.537	0.33
47_V	113_M	0.537	0.33
278_G	336_E	0.536	0.33
319_A	353_G	0.535	0.33
43_T	106_E	0.535	0.33
336_E	432_G	0.534	0.33
63_D	265_N	0.533	0.33
264_I	299_Y	0.533	0.33
292_I	423_K	0.532	0.33
423_K	430_E	0.532	0.33
304_I	357_L	0.532	0.33
346_A	432_G	0.531	0.33
297_L	315_Y	0.531	0.33
30_T	34_I	0.529	0.33
124_E	348_S	0.529	0.33
11_G	22_P	0.528	0.33
134_G	204_E	0.527	0.33
365_V	443_S	0.527	0.33
251_D	255_T	0.526	0.32
263_W	364_Q	0.526	0.32
194_K	320_S	0.525	0.32
413_R	416_E	0.525	0.32
15_S	18_H	0.525	0.32
41_D	185_G	0.525	0.32
76_D	451_I	0.523	0.32
280_R	295_A	0.522	0.32
163_A	166_E	0.522	0.32
87_I	90_V	0.522	0.32
117_A	423_K	0.522	0.32
376_N	399_A	0.522	0.32
28_Q	153_D	0.522	0.32
102_Q	129_I	0.521	0.32
320_S	328_M	0.520	0.32
385_A	452_V	0.520	0.32
71_A	224_I	0.518	0.32
217_R	309_A	0.518	0.32
371_I	413_R	0.518	0.32
334_G	345_V	0.518	0.32
373_M	420_C	0.518	0.32
331_S	336_E	0.517	0.32
113_M	141_Q	0.517	0.32
186_L	235_R	0.517	0.32
43_T	103_H	0.516	0.32
293_I	315_Y	0.515	0.31
88_Q	203_E	0.515	0.31
11_G	18_H	0.515	0.31
107_F	112_C	0.515	0.31
194_K	235_R	0.514	0.31
191_L	419_V	0.514	0.31
281_V	373_M	0.513	0.31
36_R	104_E	0.513	0.31
353_G	364_Q	0.513	0.31
399_A	409_M	0.511	0.31
76_D	222_R	0.510	0.31
423_K	444_R	0.509	0.31
93_H	105_V	0.509	0.31
35_A	40_K	0.508	0.31
102_Q	106_E	0.508	0.31
430_E	445_G	0.507	0.31
162_S	190_G	0.507	0.31
104_E	111_Q	0.507	0.31
437_A	440_R	0.507	0.31
312_L	316_L	0.507	0.31
9_K	401_V	0.507	0.31
438_K	445_G	0.506	0.31
440_R	450_K	0.506	0.31
56_T	335_A	0.505	0.31
24_K	153_D	0.504	0.31
337_V	340_Q	0.504	0.31
413_R	440_R	0.504	0.31
60_H	335_A	0.503	0.30
20_V	75_P	0.503	0.30
220_I	426_E	0.503	0.30
55_L	267_F	0.503	0.30
59_G	62_T	0.502	0.30
374_E	394_E	0.502	0.30
182_Q	305_R	0.502	0.30
87_I	113_M	0.502	0.30
73_N	83_I	0.501	0.30
24_K	74_L	0.501	0.30
73_N	78_V	0.501	0.30
15_S	21_G	0.501	0.30
319_A	357_L	0.500	0.30
126_G	142_T	0.500	0.30
115_F	260_V	0.500	0.30
184_T	190_G	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4rqoA	2	0.9846	100	0.175	Contact Map
2iafA	1	0.3033	100	0.74	Contact Map
1ygyA	4	0.4396	99.5	0.918	Contact Map
2hp0A	2	0.5341	69	0.978	Contact Map
1szqA	2	0.5253	51.2	0.98	Contact Map
3tsoC	2	0.1121	23.4	0.983	Contact Map
4zacA	2	0.367	19.5	0.984	Contact Map
4d0gC	1	0.0989	18.5	0.984	Contact Map
1owfB	1	0.1978	16.3	0.984	Contact Map
4n1vA	2	0.1934	15.2	0.985	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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