GREMLIN Database
YBIB - Uncharacterized protein YbiB
UniProt: P30177 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11580
Length: 320 (306)
Sequences: 4238 (2772)
Seq/√Len: 158.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
280_R285_S4.0981.00
22_R64_E3.5391.00
234_A240_P3.2401.00
19_D52_K3.0991.00
258_D264_L2.7301.00
26_R64_E2.7151.00
234_A298_C2.6731.00
270_D273_T2.6511.00
276_Q280_R2.6321.00
209_G252_V2.5731.00
146_A150_E2.4971.00
38_P174_R2.4851.00
100_L278_I2.4711.00
148_L154_V2.4291.00
208_I243_N2.4161.00
26_R68_N2.4131.00
44_G47_I2.3991.00
13_G24_T2.3791.00
30_A69_H2.3681.00
60_L217_D2.3091.00
28_L45_V2.1711.00
293_K317_N2.1671.00
21_D24_T2.1401.00
104_L292_L2.1111.00
144_A154_V2.0841.00
244_L253_L2.0431.00
268_A274_T2.0411.00
308_T311_D2.0151.00
108_L300_L2.0011.00
38_P41_E2.0011.00
236_P265_L1.9811.00
223_L302_A1.9681.00
205_P241_Q1.9671.00
228_T241_Q1.9631.00
216_S245_I1.9601.00
132_L272_E1.9541.00
110_F300_L1.9151.00
30_A68_N1.9111.00
25_A62_F1.9011.00
140_H143_Q1.8831.00
34_N69_H1.8771.00
314_A317_N1.8621.00
105_L110_F1.8601.00
223_L298_C1.8391.00
209_G213_K1.8191.00
256_K259_T1.8011.00
243_N250_M1.7931.00
242_I253_L1.7901.00
61_G65_A1.7701.00
256_K264_L1.7511.00
30_A65_A1.7221.00
32_M42_L1.7151.00
97_L291_S1.7011.00
105_L299_C1.6791.00
222_A245_I1.6781.00
145_Q149_D1.6591.00
196_A220_G1.6451.00
66_M188_A1.6321.00
31_H36_E1.6221.00
47_I177_V1.6181.00
269_K274_T1.6101.00
22_R61_G1.6091.00
221_R246_D1.5851.00
86_P198_R1.5791.00
239_C254_Y1.5661.00
101_L296_M1.5581.00
289_P317_N1.5391.00
183_T207_Y1.5351.00
279_E283_A1.5211.00
306_A312_G1.5201.00
139_L143_Q1.5081.00
62_F180_S1.4941.00
229_E238_R1.4891.00
228_T238_R1.4721.00
50_R54_E1.4631.00
74_T145_Q1.4571.00
72_K192_A1.4511.00
297_A301_V1.4471.00
83_I299_C1.4381.00
44_G175_M1.4331.00
129_I278_I1.4261.00
29_Y62_F1.4151.00
22_R217_D1.3941.00
297_A312_G1.3901.00
265_L287_P1.3771.00
133_M275_A1.3731.00
129_I275_A1.3501.00
28_L37_V1.3471.00
13_G18_R1.3421.00
143_Q146_A1.3411.00
47_I51_I1.3401.00
57_A217_D1.3381.00
215_F222_A1.3381.00
241_Q252_V1.3361.00
39_D174_R1.3361.00
307_A311_D1.3311.00
40_L174_R1.3311.00
56_E60_L1.3181.00
239_C256_K1.3091.00
42_L171_M1.2861.00
305_E315_R1.2601.00
37_V42_L1.2321.00
118_S128_T1.2181.00
241_Q254_Y1.2081.00
9_E24_T1.2071.00
192_A195_E1.2001.00
56_E214_F1.2001.00
227_G238_R1.1961.00
139_L147_K1.1941.00
81_M196_A1.1911.00
243_N252_V1.1911.00
165_L168_Q1.1841.00
213_K216_S1.1781.00
293_K313_L1.1651.00
110_F303_T1.1651.00
221_R244_L1.1641.00
297_A313_L1.1631.00
40_L43_G1.1631.00
135_I153_P1.1621.00
269_K273_T1.1571.00
65_A69_H1.1551.00
26_R65_A1.1501.00
310_S314_A1.1451.00
25_A61_G1.1441.00
110_F305_E1.1381.00
281_C288_I1.1161.00
216_S250_M1.1141.00
101_L105_L1.1081.00
66_M165_L1.0940.99
30_A34_N1.0910.99
82_P195_E1.0880.99
45_V62_F1.0840.99
228_T239_C1.0800.99
234_A255_E1.0780.99
237_Q266_P1.0730.99
255_E260_A1.0680.99
118_S131_E1.0650.99
234_A294_I1.0640.99
168_Q171_M1.0590.99
41_E174_R1.0580.99
15_N177_V1.0550.99
144_A161_F1.0440.99
23_D26_R1.0410.99
236_P291_S1.0390.99
256_K260_A1.0370.99
13_G17_A1.0290.99
127_E157_P1.0240.99
276_Q279_E1.0230.99
105_L112_V1.0230.99
244_L301_V1.0180.99
82_P113_V1.0120.99
265_L290_E1.0100.99
312_G316_V1.0060.99
95_A277_W1.0060.99
15_N47_I0.9950.99
170_A174_R0.9900.99
33_L66_M0.9900.99
235_N238_R0.9820.99
52_K58_E0.9790.99
306_A315_R0.9750.99
240_P257_Q0.9660.99
315_R318_Q0.9660.99
260_A313_L0.9660.99
289_P293_K0.9640.99
54_E59_M0.9630.99
40_L171_M0.9600.99
123_R270_D0.9580.99
271_P275_A0.9580.99
63_Y218_I0.9550.99
120_D159_G0.9520.99
105_L111_P0.9480.99
245_I250_M0.9390.98
197_L221_R0.9290.98
262_S294_I0.9280.98
54_E178_R0.9260.98
37_V41_E0.9230.98
56_E213_K0.9220.98
59_M214_F0.9150.98
199_L225_M0.9130.98
31_H37_V0.9130.98
19_D57_A0.9110.98
57_A61_G0.9100.98
197_L302_A0.9090.98
85_I101_L0.9050.98
281_C292_L0.9050.98
60_L64_E0.9030.98
272_E276_Q0.9000.98
147_K151_H0.8990.98
262_S313_L0.8970.98
111_P149_D0.8950.98
275_A279_E0.8930.98
223_L301_V0.8920.98
81_M197_L0.8870.98
105_L108_L0.8840.98
280_R286_E0.8820.98
202_V211_V0.8820.98
228_T254_Y0.8810.98
44_G177_V0.8800.98
27_G31_H0.8800.98
229_E235_N0.8770.98
60_L214_F0.8770.98
211_V224_L0.8740.97
42_L168_Q0.8710.97
144_A148_L0.8710.97
32_M168_Q0.8670.97
226_H230_G0.8670.97
56_E217_D0.8660.97
138_T160_A0.8660.97
287_P290_E0.8620.97
147_K154_V0.8620.97
20_L58_E0.8620.97
39_D170_A0.8580.97
86_P126_T0.8560.97
39_D171_M0.8550.97
85_I198_R0.8480.97
19_D55_G0.8470.97
48_A52_K0.8460.97
67_Q192_A0.8390.97
85_I102_A0.8390.97
26_R61_G0.8360.97
76_P149_D0.8330.97
94_Q231_E0.8310.97
227_G235_N0.8290.97
245_I248_E0.8260.96
71_I163_P0.8210.96
314_A318_Q0.8190.96
66_M184_L0.8170.96
99_P130_F0.8160.96
103_I107_K0.8150.96
209_G243_N0.8130.96
301_V306_A0.8110.96
197_L220_G0.8070.96
86_P101_L0.8070.96
263_E290_E0.8040.96
146_A149_D0.8030.96
22_R60_L0.8030.96
207_Y210_R0.8020.96
33_L188_A0.7990.96
25_A180_S0.7980.96
92_R121_P0.7980.96
104_L296_M0.7980.96
244_L251_R0.7890.95
77_A149_D0.7860.95
141_G145_Q0.7840.95
83_I112_V0.7830.95
304_G312_G0.7820.95
103_I153_P0.7820.95
132_L271_P0.7810.95
301_V308_T0.7790.95
91_A94_Q0.7770.95
9_E13_G0.7760.95
144_A156_M0.7740.95
246_D251_R0.7740.95
129_I133_M0.7690.95
100_L282_L0.7670.95
234_A260_A0.7630.95
277_W281_C0.7610.94
35_G167_K0.7600.94
259_T310_S0.7510.94
10_I14_K0.7500.94
43_G171_M0.7480.94
26_R30_A0.7470.94
67_Q218_I0.7470.94
75_P148_L0.7370.93
203_S207_Y0.7350.93
12_R16_H0.7350.93
301_V309_I0.7320.93
290_E317_N0.7310.93
143_Q147_K0.7300.93
28_L32_M0.7300.93
105_L296_M0.7280.93
200_S211_V0.7280.93
10_I13_G0.7250.93
39_D167_K0.7240.93
33_L167_K0.7210.93
297_A309_I0.7210.93
59_M183_T0.7200.93
85_I126_T0.7200.93
216_S249_G0.7170.93
236_P266_P0.7170.93
213_K250_M0.7100.92
197_L303_T0.7090.92
93_K123_R0.7050.92
46_L165_L0.7040.92
220_G247_R0.7020.92
258_D263_E0.7020.92
223_L253_L0.7020.92
95_A288_I0.7010.92
93_K267_Q0.7000.92
136_T143_Q0.7000.92
140_H160_A0.6980.91
28_L31_H0.6970.91
70_T188_A0.6950.91
49_L54_E0.6950.91
8_K12_R0.6950.91
58_E61_G0.6940.91
229_E237_Q0.6930.91
205_P252_V0.6930.91
144_A147_K0.6900.91
29_Y180_S0.6900.91
83_I110_F0.6840.91
102_A153_P0.6840.91
100_L281_C0.6820.91
165_L188_A0.6810.90
236_P262_S0.6810.90
91_A122_T0.6800.90
311_D315_R0.6790.90
15_N51_I0.6730.90
253_L301_V0.6670.90
236_P290_E0.6660.89
43_G47_I0.6630.89
85_I299_C0.6620.89
304_G315_R0.6610.89
309_I312_G0.6600.89
71_I141_G0.6600.89
105_L300_L0.6600.89
236_P287_P0.6600.89
281_C286_E0.6590.89
268_A277_W0.6590.89
113_V156_M0.6580.89
22_R57_A0.6540.89
213_K217_D0.6540.89
48_A51_I0.6500.88
179_N182_H0.6480.88
73_L144_A0.6470.88
208_I252_V0.6450.88
62_F184_L0.6430.88
126_T129_I0.6430.88
136_T139_L0.6420.88
127_E131_E0.6410.88
56_E210_R0.6400.88
65_A68_N0.6390.87
132_L275_A0.6320.87
55_G58_E0.6300.87
278_I282_L0.6280.87
273_T276_Q0.6280.87
113_V148_L0.6280.87
199_L302_A0.6270.86
47_I175_M0.6270.86
212_A245_I0.6260.86
85_I199_L0.6260.86
239_C264_L0.6250.86
124_V271_P0.6240.86
298_C309_I0.6220.86
223_L309_I0.6200.86
223_L242_I0.6180.86
301_V305_E0.6150.85
159_G173_W0.6150.85
300_L305_E0.6140.85
307_A315_R0.6130.85
64_E68_N0.6120.85
44_G51_I0.6070.85
208_I241_Q0.6040.84
221_R304_G0.6040.84
63_Y184_L0.6030.84
23_D27_G0.6030.84
83_I303_T0.6030.84
103_I282_L0.6010.84
142_G145_Q0.5990.84
103_I135_I0.5970.84
205_P228_T0.5950.84
276_Q285_S0.5950.84
44_G171_M0.5950.84
106_H109_G0.5950.84
200_S224_L0.5940.83
300_L316_V0.5920.83
9_E18_R0.5890.83
300_L306_A0.5850.82
311_D314_A0.5850.82
293_K297_A0.5840.82
63_Y67_Q0.5840.82
229_E240_P0.5810.82
198_R222_A0.5810.82
107_K151_H0.5800.82
44_G48_A0.5780.82
9_E12_R0.5770.82
200_S215_F0.5760.82
63_Y66_M0.5760.82
89_N185_A0.5750.81
100_L292_L0.5750.81
81_M305_E0.5750.81
11_G14_K0.5740.81
256_K294_I0.5730.81
32_M45_V0.5720.81
284_G289_P0.5710.81
73_L156_M0.5690.81
191_F195_E0.5680.81
262_S293_K0.5670.81
103_I278_I0.5670.81
107_K282_L0.5670.81
89_N186_K0.5660.80
199_L299_C0.5650.80
133_M279_E0.5630.80
268_A288_I0.5620.80
313_L317_N0.5600.80
83_I197_L0.5590.80
286_E290_E0.5570.79
38_P171_M0.5560.79
40_L47_I0.5550.79
147_K153_P0.5550.79
304_G307_A0.5540.79
63_Y187_L0.5540.79
260_A309_I0.5530.79
262_S265_L0.5520.79
8_K11_G0.5490.78
297_A308_T0.5480.78
75_P145_Q0.5480.78
25_A29_Y0.5460.78
120_D203_S0.5450.78
299_C302_A0.5440.78
100_L124_V0.5430.78
24_T61_G0.5430.78
277_W288_I0.5380.77
11_G177_V0.5370.77
111_P152_Q0.5370.77
242_I255_E0.5360.77
101_L104_L0.5360.77
54_E58_E0.5360.77
63_Y70_T0.5330.76
216_S248_E0.5330.76
210_R213_K0.5330.76
135_I147_K0.5320.76
300_L315_R0.5310.76
46_L168_Q0.5300.76
220_G304_G0.5290.76
221_R301_V0.5280.76
286_E289_P0.5270.76
202_V208_I0.5260.75
15_N50_R0.5250.75
50_R176_G0.5250.75
96_N114_V0.5240.75
83_I195_E0.5220.75
63_Y188_A0.5190.74
225_M234_A0.5180.74
101_L292_L0.5180.74
228_T235_N0.5150.74
94_Q97_L0.5150.74
89_N96_N0.5140.74
29_Y168_Q0.5140.74
223_L244_L0.5140.74
83_I302_A0.5130.74
260_A294_I0.5130.74
142_G146_A0.5120.73
268_A275_A0.5110.73
25_A58_E0.5100.73
59_M210_R0.5100.73
82_P111_P0.5090.73
17_A51_I0.5090.73
10_I48_A0.5080.73
246_D249_G0.5080.73
131_E137_P0.5080.73
81_M111_P0.5060.73
22_R26_R0.5060.73
77_A145_Q0.5020.72
60_L63_Y0.5020.72
67_Q195_E0.5020.72
178_R207_Y0.5010.72
168_Q181_A0.5010.72
289_P292_L0.5000.72
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4muoA 2 0.9688 100 0.079 Contact Map
4giuA 2 0.9812 100 0.087 Contact Map
1vquA 2 0.9625 100 0.094 Contact Map
1khdA 2 0.9563 100 0.096 Contact Map
1o17A 2 0.9656 100 0.112 Contact Map
4gtnA 2 0.9406 100 0.114 Contact Map
4hkmA 2 0.95 100 0.115 Contact Map
2elcA 4 0.95 100 0.124 Contact Map
3h5qA 2 0.875 100 0.315 Contact Map
4eadA 2 0.8531 100 0.324 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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