THIF - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

THIF - Sulfur carrier protein ThiS adenylyltransferase

UniProt:	P30138	Sequences: MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIQLTALQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMVLTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGELRLFDGKSSQWRSLALRRASGCPVCGGSNADPV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11587
Length:	251 (221)
Sequences:	8867 (5841)
Seq/√Len:	392.9

ECOLI - THIF MOEB TCDA
BACSU - MOEB THIF TCDA
HALSA - Q9HST5
SULSO - Q980J4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
54_T	99_Q	3.510	1.00
54_T	101_T	3.318	1.00
88_Q	92_T	3.309	1.00
81_R	89_Q	3.169	1.00
30_Q	56_V	3.135	1.00
82_P	104_Q	3.089	1.00
60_D	106_R	3.007	1.00
30_Q	54_T	2.982	1.00
56_V	119_A	2.968	1.00
74_F	86_V	2.550	1.00
204_E	207_K	2.532	1.00
44_A	91_L	2.443	1.00
169_C	172_C	2.366	1.00
43_A	123_L	2.354	1.00
123_L	205_A	2.331	1.00
33_I	44_A	2.309	1.00
77_E	93_Q	2.297	1.00
78_D	81_R	2.231	1.00
88_Q	102_A	2.201	1.00
32_L	119_A	2.198	1.00
76_T	96_P	2.165	1.00
73_L	87_S	2.151	1.00
85_Q	104_Q	2.126	1.00
121_V	205_A	2.104	1.00
149_A	197_M	2.046	1.00
149_A	201_Q	2.041	1.00
122_V	139_C	2.027	1.00
56_V	103_L	1.992	1.00
29_S	209_L	1.917	1.00
113_K	141_A	1.914	1.00
85_Q	102_A	1.904	1.00
75_T	93_Q	1.813	1.00
84_S	102_A	1.762	1.00
117_A	142_L	1.729	1.00
24_Q	28_D	1.725	1.00
84_S	104_Q	1.672	1.00
36_L	57_L	1.665	1.00
156_G	197_M	1.663	1.00
10_S	14_L	1.659	1.00
126_T	131_T	1.635	1.00
138_A	142_L	1.617	1.00
113_K	142_L	1.588	1.00
18_I	22_G	1.583	1.00
18_I	210_S	1.562	1.00
75_T	90_R	1.556	1.00
41_T	73_L	1.550	1.00
62_D	82_P	1.541	1.00
56_V	101_T	1.524	1.00
46_Y	195_G	1.519	1.00
32_L	58_A	1.512	1.00
13_I	20_L	1.497	1.00
107_L	112_L	1.489	1.00
48_A	91_L	1.478	1.00
26_L	206_I	1.468	1.00
81_R	85_Q	1.466	1.00
82_P	85_Q	1.457	1.00
137_A	171_R	1.428	1.00
9_Y	95_N	1.420	1.00
42_P	45_L	1.418	1.00
44_A	57_L	1.383	1.00
78_D	90_R	1.378	1.00
31_V	121_V	1.373	1.00
90_R	93_Q	1.361	1.00
160_V	208_L	1.336	1.00
8_R	76_T	1.325	1.00
48_A	98_I	1.302	1.00
43_A	125_C	1.298	1.00
30_Q	119_A	1.296	1.00
105_Q	111_A	1.293	1.00
75_T	78_D	1.286	1.00
222_F	227_S	1.269	1.00
137_A	141_A	1.264	1.00
12_Q	23_Q	1.245	1.00
192_P	203_L	1.204	1.00
20_L	24_Q	1.195	1.00
36_L	87_S	1.194	1.00
25_K	29_S	1.187	1.00
158_L	200_L	1.184	1.00
91_L	98_I	1.182	1.00
108_T	111_A	1.178	1.00
67_N	83_K	1.172	1.00
88_Q	100_L	1.139	1.00
91_L	100_L	1.133	1.00
136_N	140_V	1.126	1.00
200_L	229_W	1.122	1.00
34_I	135_I	1.116	1.00
45_L	72_I	1.114	1.00
45_L	49_G	1.101	1.00
113_K	138_A	1.098	1.00
198_G	202_A	1.095	1.00
151_A	194_V	1.093	1.00
112_L	138_A	1.084	1.00
27_L	97_D	1.076	1.00
95_N	98_I	1.066	1.00
222_F	229_W	1.064	1.00
136_N	146_L	1.061	1.00
223_D	226_S	1.061	1.00
81_R	86_V	1.061	1.00
92_T	98_I	1.057	1.00
135_I	146_L	1.057	1.00
85_Q	88_Q	1.054	1.00
171_R	174_W	1.048	1.00
32_L	56_V	1.044	1.00
74_F	78_D	1.034	1.00
195_G	199_T	1.028	1.00
126_T	135_I	1.025	1.00
183_N	186_T	1.011	1.00
63_V	74_F	0.992	1.00
196_V	222_F	0.992	1.00
78_D	89_Q	0.992	1.00
50_A	206_I	0.983	1.00
30_Q	101_T	0.978	1.00
124_D	135_I	0.977	1.00
121_V	208_L	0.973	1.00
61_D	83_K	0.965	1.00
78_D	86_V	0.954	1.00
49_G	94_L	0.954	1.00
138_A	141_A	0.954	1.00
133_Q	175_P	0.954	1.00
147_I	208_L	0.950	1.00
128_N	131_T	0.947	1.00
48_A	55_L	0.947	1.00
19_A	22_G	0.936	1.00
61_D	67_N	0.933	1.00
183_N	187_A	0.932	1.00
121_V	147_I	0.932	1.00
169_C	173_L	0.910	1.00
63_V	86_V	0.902	1.00
32_L	116_V	0.901	1.00
116_V	119_A	0.898	1.00
45_L	90_R	0.891	1.00
34_I	58_A	0.890	1.00
220_R	229_W	0.879	1.00
12_Q	69_Q	0.873	1.00
25_K	211_G	0.872	1.00
21_D	25_K	0.871	1.00
44_A	87_S	0.870	1.00
162_T	165_W	0.866	1.00
109_G	137_A	0.865	1.00
170_Y	173_L	0.859	1.00
41_T	45_L	0.856	1.00
182_R	187_A	0.854	1.00
101_T	118_R	0.853	1.00
133_Q	137_A	0.853	1.00
89_Q	93_Q	0.853	1.00
196_V	200_L	0.851	1.00
123_L	201_Q	0.846	1.00
139_C	146_L	0.844	1.00
134_E	138_A	0.836	1.00
114_D	117_A	0.832	1.00
60_D	104_Q	0.826	1.00
15_L	154_F	0.825	1.00
121_V	209_L	0.821	1.00
34_I	107_L	0.817	1.00
124_D	132_R	0.815	1.00
112_L	134_E	0.807	1.00
147_I	205_A	0.807	1.00
168_G	172_C	0.804	1.00
42_P	195_G	0.800	1.00
203_L	224_G	0.799	1.00
105_Q	114_D	0.799	1.00
136_N	169_C	0.798	1.00
220_R	227_S	0.790	1.00
118_R	144_T	0.788	1.00
39_L	201_Q	0.782	1.00
31_V	205_A	0.778	1.00
45_L	94_L	0.778	1.00
41_T	74_F	0.773	1.00
120_D	144_T	0.769	1.00
89_Q	92_T	0.765	1.00
151_A	189_V	0.763	1.00
182_R	186_T	0.761	1.00
36_L	84_S	0.761	1.00
133_Q	171_R	0.760	1.00
158_L	197_M	0.754	1.00
23_Q	27_L	0.754	1.00
73_L	91_L	0.753	1.00
189_V	194_V	0.751	1.00
116_V	138_A	0.748	1.00
122_V	135_I	0.748	1.00
169_C	174_W	0.747	1.00
171_R	175_P	0.743	1.00
68_L	79_I	0.742	1.00
168_G	217_G	0.737	1.00
36_L	44_A	0.735	1.00
193_V	224_G	0.735	1.00
92_T	99_Q	0.732	1.00
44_A	55_L	0.731	1.00
55_L	91_L	0.727	1.00
203_L	222_F	0.727	1.00
170_Y	174_W	0.724	1.00
136_N	172_C	0.724	1.00
86_V	89_Q	0.722	1.00
46_Y	72_I	0.722	1.00
31_V	52_V	0.722	1.00
38_G	194_V	0.722	1.00
46_Y	202_A	0.720	1.00
122_V	144_T	0.717	1.00
65_L	79_I	0.716	1.00
154_F	225_K	0.707	1.00
7_M	13_I	0.707	1.00
46_Y	199_T	0.706	1.00
208_L	215_P	0.704	1.00
24_Q	27_L	0.703	1.00
160_V	204_E	0.702	1.00
177_N	180_P	0.697	1.00
58_A	115_A	0.695	1.00
107_L	111_A	0.692	1.00
7_M	10_S	0.692	1.00
113_K	117_A	0.689	0.99
109_G	134_E	0.688	0.99
58_A	107_L	0.685	0.99
12_Q	50_A	0.682	0.99
12_Q	15_L	0.681	0.99
25_K	210_S	0.681	0.99
147_I	160_V	0.679	0.99
162_T	166_E	0.675	0.99
26_L	53_G	0.674	0.99
65_L	76_T	0.671	0.99
224_G	227_S	0.670	0.99
9_Y	98_I	0.666	0.99
116_V	142_L	0.665	0.99
25_K	28_D	0.665	0.99
30_Q	118_R	0.664	0.99
124_D	148_T	0.661	0.99
84_S	100_L	0.661	0.99
22_G	210_S	0.656	0.99
43_A	201_Q	0.656	0.99
49_G	69_Q	0.654	0.99
162_T	167_Q	0.652	0.99
63_V	73_L	0.648	0.99
85_Q	89_Q	0.646	0.99
221_L	230_R	0.645	0.99
55_L	98_I	0.644	0.99
132_R	150_S	0.643	0.99
206_I	210_S	0.641	0.99
50_A	191_G	0.641	0.99
42_P	46_Y	0.640	0.99
43_A	198_G	0.637	0.99
205_A	209_L	0.636	0.99
157_Q	160_V	0.629	0.99
212_I	225_K	0.627	0.99
76_T	79_I	0.625	0.99
128_N	132_R	0.623	0.99
111_A	115_A	0.623	0.99
78_D	93_Q	0.617	0.99
194_V	199_T	0.617	0.99
44_A	73_L	0.616	0.99
190_V	203_L	0.614	0.99
7_M	65_L	0.613	0.99
53_G	95_N	0.613	0.99
42_P	72_I	0.609	0.99
8_R	97_D	0.608	0.99
126_T	132_R	0.601	0.99
212_I	215_P	0.598	0.99
26_L	52_V	0.598	0.99
170_Y	175_P	0.597	0.99
29_S	52_V	0.596	0.99
47_L	55_L	0.595	0.99
37_G	40_G	0.595	0.99
67_N	70_R	0.593	0.98
29_S	120_D	0.593	0.98
171_R	176_D	0.591	0.98
192_P	206_I	0.590	0.98
10_S	13_I	0.590	0.98
175_P	178_Q	0.589	0.98
21_D	24_Q	0.589	0.98
48_A	100_L	0.586	0.98
62_D	104_Q	0.584	0.98
177_N	181_E	0.584	0.98
140_V	172_C	0.583	0.98
61_D	66_S	0.582	0.98
67_N	71_Q	0.580	0.98
145_P	208_L	0.578	0.98
13_I	23_Q	0.578	0.98
124_D	127_D	0.577	0.98
178_Q	181_E	0.577	0.98
103_L	119_A	0.574	0.98
41_T	63_V	0.573	0.98
73_L	90_R	0.569	0.98
33_I	47_L	0.565	0.98
57_L	100_L	0.564	0.98
15_L	18_I	0.564	0.98
57_L	87_S	0.563	0.98
59_D	84_S	0.561	0.98
31_V	123_L	0.558	0.98
52_V	209_L	0.557	0.98
131_T	134_E	0.556	0.98
64_H	67_N	0.554	0.98
70_R	83_K	0.554	0.98
61_D	127_D	0.554	0.98
90_R	94_L	0.553	0.98
67_N	127_D	0.552	0.98
176_D	179_E	0.552	0.98
116_V	122_V	0.550	0.98
36_L	74_F	0.548	0.97
116_V	139_C	0.546	0.97
38_G	69_Q	0.546	0.97
147_I	201_Q	0.543	0.97
148_T	159_M	0.542	0.97
42_P	198_G	0.541	0.97
200_L	203_L	0.540	0.97
83_K	127_D	0.539	0.97
189_V	193_V	0.539	0.97
42_P	199_T	0.537	0.97
116_V	144_T	0.535	0.97
153_G	193_V	0.534	0.97
156_G	190_V	0.533	0.97
140_V	161_L	0.532	0.97
171_R	177_N	0.531	0.97
107_L	116_V	0.522	0.97
115_A	119_A	0.521	0.97
61_D	70_R	0.520	0.97
192_P	199_T	0.518	0.96
33_I	40_G	0.517	0.96
214_T	226_S	0.515	0.96
199_T	203_L	0.515	0.96
210_S	215_P	0.513	0.96
173_L	177_N	0.510	0.96
18_I	23_Q	0.510	0.96
207_K	213_E	0.509	0.96
159_M	163_P	0.507	0.96
37_G	71_Q	0.506	0.96
119_A	144_T	0.506	0.96
154_F	212_I	0.505	0.96
39_L	194_V	0.505	0.96
62_D	65_L	0.504	0.96
30_Q	120_D	0.503	0.96
55_L	100_L	0.503	0.96
221_L	224_G	0.501	0.96
172_C	175_P	0.501	0.96
35_G	40_G	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1zud1	2	0.9562	100	0.146	Contact Map
1jw9B	2	0.9442	100	0.178	Contact Map
1tt5B	1	0.9841	100	0.214	Contact Map
4gslA	2	0.9841	100	0.22	Contact Map
3h5nA	3	0.9562	100	0.23	Contact Map
2nvuB	1	0.9841	100	0.231	Contact Map
3h8vA	2	0.8287	100	0.232	Contact Map
1y8qA	1	0.9124	100	0.249	Contact Map
3ruiA	2	0.9841	100	0.254	Contact Map
1y8qB	1	0.9402	100	0.276	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0086 seconds.