GREMLIN Database
HYPF - Carbamoyltransferase HypF
UniProt: P30131 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11551
Length: 750 (725)
Sequences: 1338 (1088)
Seq/√Len: 40.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
480_A498_A5.1071.00
116_M129_I5.0541.00
163_D167_R4.7021.00
480_A500_T4.6591.00
221_I304_N4.4731.00
233_S287_C4.2191.00
26_V61_L4.0161.00
508_E525_C4.0041.00
264_A279_D3.8781.00
35_L50_L3.8751.00
152_V356_V3.8091.00
111_A133_H3.5341.00
399_A730_L3.5161.00
115_E129_I3.3621.00
233_S289_D3.3471.00
60_Q64_H3.3291.00
224_F334_N3.3231.00
673_A707_R3.3061.00
450_V738_A3.2571.00
406_C413_A3.2321.00
229_D232_N3.2231.00
511_A533_A3.2211.00
130_N178_P3.1351.00
142_R154_A3.1151.00
51_R84_L3.1101.00
209_Q347_G3.1041.00
227_A320_M3.0931.00
451_H463_A3.0581.00
422_L459_S3.0511.00
161_A183_E3.0271.00
33_L60_Q2.9381.00
617_E621_A2.9281.00
190_W347_G2.9031.00
451_H472_T2.8531.00
209_Q214_K2.8371.00
247_A617_E2.7811.00
684_A715_F2.7731.00
357_Q437_L2.7351.00
260_L278_V2.7241.00
723_L732_L2.6981.00
700_H726_G2.6811.00
32_Q60_Q2.6511.00
481_A737_I2.6381.00
238_T241_A2.6241.00
540_D543_A2.6071.00
532_P646_D2.6061.00
334_N350_I2.5961.00
139_T359_M2.5741.00
238_T242_R2.5551.00
8_G49_R2.5511.00
626_A703_L2.5191.00
534_V553_Q2.4831.00
408_V735_G2.4421.00
489_W718_L2.4251.00
117_N312_Q2.4211.00
501_L676_F2.4201.00
484_L489_W2.4141.00
254_L299_V2.4081.00
404_T731_S2.4051.00
601_V654_W2.3931.00
68_L106_A2.3451.00
499_L517_C2.3431.00
155_A354_D2.3231.00
499_L680_M2.3091.00
206_A216_V2.3031.00
531_L594_C2.3021.00
225_H303_A2.2891.00
480_A520_V2.2561.00
415_L731_S2.2411.00
519_R689_I2.2351.00
123_R165_E2.2301.00
108_T308_H2.2181.00
190_W209_Q2.2040.99
451_H470_T2.1840.99
218_I227_A2.1680.99
199_Q202_A2.1520.99
483_C720_P2.1490.99
113_L308_H2.1240.99
125_R313_E2.1090.99
645_L675_G2.0960.99
607_C625_L2.0920.99
477_H737_I2.0870.99
191_V338_L2.0690.99
464_R472_T2.0500.99
676_F708_L2.0480.99
677_A711_Y2.0460.99
12_R42_D2.0450.99
594_C672_L2.0410.99
406_C731_S2.0370.99
530_G533_A2.0280.99
723_L729_G1.9990.99
495_D521_N1.9960.99
328_K340_D1.9930.99
500_T520_V1.9550.99
8_G51_R1.9370.99
453_A508_E1.9110.99
608_A621_A1.9110.99
603_A609_P1.8920.98
111_A114_A1.8810.98
483_C693_V1.8660.98
695_S720_P1.8620.98
32_Q64_H1.8500.98
504_I512_L1.8450.98
36_H87_E1.8250.98
477_H481_A1.8020.98
456_G461_Q1.7980.98
487_H720_P1.7960.98
323_G331_A1.7900.98
8_G85_P1.7780.98
499_L676_F1.7770.98
257_A265_R1.7720.98
485_A732_L1.7700.98
187_H352_N1.7640.98
323_G337_A1.7580.97
614_Y620_C1.7560.97
536_L549_N1.7350.97
261_P264_A1.7340.97
484_L693_V1.7290.97
296_E365_R1.7150.97
334_N354_D1.7120.97
415_L723_L1.7060.97
323_G348_F1.7050.97
287_C290_I1.7020.97
517_C679_L1.6930.97
286_L290_I1.6840.97
405_F435_L1.6840.97
384_L413_A1.6830.97
614_Y621_A1.6810.97
431_W462_W1.6780.97
626_A665_A1.6760.97
528_L683_Q1.6740.97
118_T121_E1.6310.96
484_L496_V1.6140.96
138_F438_M1.6080.96
674_Q711_Y1.6040.96
654_W664_R1.6010.96
14_R73_S1.5900.95
406_C735_G1.5740.95
541_L545_Q1.5710.95
142_R356_V1.5590.95
192_S195_E1.5490.95
264_A366_E1.5470.95
519_R528_L1.5460.95
413_A732_L1.5410.95
501_L594_C1.5380.94
262_D265_R1.5340.94
38_D91_R1.5340.94
485_A736_V1.5340.94
11_L48_V1.5280.94
192_S196_H1.5210.94
673_A711_Y1.5190.94
418_H728_G1.5140.94
451_H460_S1.5140.94
518_L525_C1.5130.94
205_A208_A1.5020.94
38_D49_R1.5010.94
246_P613_S1.5010.94
482_A729_G1.4960.94
684_A690_T1.4960.94
659_A663_Q1.4950.94
11_L58_L1.4940.94
373_R381_A1.4900.93
699_I708_L1.4860.93
482_A720_P1.4820.93
405_F438_M1.4750.93
40_C47_E1.4630.93
237_A289_D1.4610.93
236_V287_C1.4550.93
267_L377_Y1.4540.93
189_E350_I1.4540.93
724_P728_G1.4440.92
242_R346_D1.4370.92
197_A202_A1.4370.92
125_R200_E1.4290.92
529_G679_L1.4210.92
114_A121_E1.4170.92
265_R269_T1.4160.92
13_I48_V1.4150.92
545_Q611_T1.4040.91
207_I314_L1.4040.91
49_R85_P1.4030.91
694_F717_L1.4030.91
400_D458_V1.4010.91
487_H721_Q1.4010.91
188_L203_L1.3960.91
534_V549_N1.3960.91
397_L462_W1.3940.91
138_F434_A1.3910.91
226_L345_A1.3880.91
598_F668_F1.3820.91
263_A266_Q1.3800.91
364_V377_Y1.3750.90
364_V370_M1.3710.90
462_W466_M1.3710.90
232_N235_A1.3670.90
486_E720_P1.3670.90
224_F350_I1.3660.90
242_R344_I1.3520.90
246_P327_G1.3520.90
252_V297_V1.3490.89
553_Q600_A1.3420.89
480_A695_S1.3410.89
16_K103_V1.3410.89
403_N431_W1.3350.89
115_E121_E1.3250.89
460_S472_T1.3240.89
477_H518_L1.3160.88
210_L227_A1.3140.88
533_A592_S1.3120.88
483_C695_S1.3030.88
395_L435_L1.3020.88
164_K168_D1.2980.88
517_C683_Q1.2960.87
409_R412_Q1.2960.87
65_C69_A1.2890.87
225_H320_M1.2890.87
27_W169_P1.2840.87
168_D171_D1.2840.87
337_A348_F1.2830.87
450_V472_T1.2800.87
121_E129_I1.2800.87
33_L56_T1.2750.87
517_C676_F1.2750.87
397_L463_A1.2660.86
391_V739_A1.2600.86
397_L431_W1.2580.86
385_P522_Y1.2560.86
646_D649_T1.2550.86
673_A703_L1.2540.86
581_A587_N1.2480.85
27_W174_F1.2470.85
256_V259_G1.2400.85
14_R75_E1.2380.85
252_V299_V1.2330.85
504_I543_A1.2250.84
40_C91_R1.2240.84
400_D423_S1.2220.84
428_Q458_V1.2190.84
432_R465_E1.2190.84
605_L622_L1.2160.84
480_A496_V1.2110.84
10_Q77_E1.2100.84
121_E165_E1.2030.83
382_L732_L1.2000.83
477_H525_C1.1940.83
405_F416_S1.1920.83
453_A474_L1.1900.83
693_V718_L1.1900.83
550_L604_A1.1880.82
486_E722_S1.1860.82
480_A693_V1.1790.82
448_Y471_Q1.1790.82
497_I528_L1.1780.82
132_T178_P1.1770.82
189_E334_N1.1760.82
242_R345_A1.1750.82
250_L290_I1.1750.82
401_L615_E1.1740.82
532_P556_R1.1740.82
253_M311_L1.1730.82
71_I74_V1.1690.81
367_S713_A1.1670.81
36_H85_P1.1660.81
602_A608_A1.1640.81
42_D100_T1.1490.80
423_S458_V1.1470.80
537_P582_I1.1420.80
163_D179_V1.1390.80
210_L318_L1.1380.80
28_Q32_Q1.1370.80
110_P273_A1.1370.80
629_C666_W1.1360.79
208_A212_M1.1360.79
497_I517_C1.1340.79
529_G675_G1.1340.79
394_V735_G1.1320.79
424_D427_I1.1310.79
9_V76_R1.1310.79
449_V466_M1.1300.79
11_L76_R1.1290.79
691_T716_T1.1280.79
102_I441_I1.1260.79
496_V693_V1.1260.79
597_F668_F1.1250.79
267_L276_V1.1230.79
8_G79_F1.1200.79
27_W170_L1.1200.79
198_E202_A1.1120.78
252_V300_M1.1120.78
480_A484_L1.1100.78
703_L707_R1.1090.78
551_L579_A1.1050.78
56_T60_Q1.1050.78
272_A380_D1.1020.77
205_A209_Q1.0990.77
605_L665_A1.0960.77
383_A411_E1.0940.77
414_V442_Y1.0920.77
448_Y469_P1.0900.77
202_A349_L1.0900.77
149_P177_Q1.0880.76
36_H51_R1.0860.76
138_F405_F1.0850.76
691_T718_L1.0820.76
127_P188_L1.0810.76
369_E725_A1.0790.76
206_A218_I1.0710.75
108_T113_L1.0710.75
336_Q340_D1.0700.75
601_V664_R1.0690.75
473_V737_I1.0650.75
402_K615_E1.0650.75
58_L76_R1.0620.75
27_W31_Q1.0590.74
358_R430_Q1.0590.74
49_R79_F1.0570.74
670_D707_R1.0550.74
450_V473_V1.0540.74
107_A273_A1.0530.74
451_H469_P1.0510.74
328_K426_G1.0480.74
218_I225_H1.0460.74
304_N307_Q1.0390.73
10_Q47_E1.0380.73
607_C621_A1.0380.73
206_A310_L1.0370.73
188_L306_L1.0330.73
635_P653_Q1.0320.73
365_R702_R1.0320.73
712_L717_L1.0310.72
498_A693_V1.0310.72
724_P729_G1.0300.72
59_V63_Q1.0270.72
207_I313_E1.0230.72
117_N125_R1.0230.72
483_C487_H1.0230.72
450_V471_Q1.0190.72
400_D506_M1.0160.71
535_A592_S1.0150.71
314_L318_L1.0090.71
484_L718_L1.0070.71
50_L71_I1.0020.70
191_V350_I1.0000.70
397_L449_V0.9980.70
580_R584_R0.9930.70
341_L344_I0.9930.70
104_P177_Q0.9930.70
435_L462_W0.9910.69
42_D45_G0.9900.69
122_R161_A0.9900.69
118_T124_Y0.9860.69
438_M442_Y0.9810.69
35_L52_E0.9810.69
295_N624_A0.9790.68
628_S662_N0.9780.68
395_L449_V0.9760.68
647_L650_F0.9710.68
303_A307_Q0.9710.68
247_A613_S0.9700.68
160_P183_E0.9690.68
517_C529_G0.9670.68
337_A341_L0.9650.67
260_L265_R0.9610.67
333_S354_D0.9570.67
634_H667_A0.9560.67
712_L715_F0.9550.67
555_L579_A0.9540.66
553_Q651_W0.9530.66
702_R706_A0.9440.66
273_A308_H0.9420.65
143_A150_F0.9410.65
11_L74_V0.9410.65
331_A340_D0.9410.65
405_F434_A0.9390.65
569_S609_P0.9380.65
667_A671_A0.9370.65
209_Q216_V0.9350.65
13_I74_V0.9350.65
242_R341_L0.9280.64
253_M320_M0.9280.64
634_H638_M0.9250.64
142_R354_D0.9220.64
100_T133_H0.9210.64
215_I344_I0.9200.64
485_A723_L0.9200.64
10_Q49_R0.9190.64
634_H664_R0.9180.63
116_M121_E0.9160.63
636_V671_A0.9130.63
720_P725_A0.9120.63
123_R129_I0.9120.63
401_L421_D0.9120.63
160_P163_D0.9120.63
457_Y504_I0.9110.63
12_R47_E0.9100.63
423_S540_D0.9090.63
382_L485_A0.9080.63
409_R414_V0.9030.62
278_V299_V0.9020.62
626_A629_C0.8980.62
397_L459_S0.8960.62
161_A164_K0.8960.62
620_C698_V0.8960.62
358_R735_G0.8950.61
338_L350_I0.8950.61
663_Q667_A0.8940.61
206_A347_G0.8930.61
582_I588_A0.8930.61
549_N552_A0.8930.61
119_P124_Y0.8920.61
654_W671_A0.8900.61
669_H703_L0.8860.61
124_Y127_P0.8820.60
277_L296_E0.8820.60
294_L614_Y0.8820.60
358_R433_E0.8810.60
460_S464_R0.8790.60
720_P723_L0.8770.60
612_L618_A0.8770.60
101_Q381_A0.8750.60
577_V581_A0.8720.59
345_A348_F0.8710.59
693_V720_P0.8710.59
707_R711_Y0.8700.59
625_L661_V0.8690.59
158_L179_V0.8690.59
228_C319_V0.8680.59
694_F712_L0.8650.59
397_L435_L0.8640.59
51_R85_P0.8600.58
436_R440_N0.8600.58
413_A735_G0.8580.58
220_G303_A0.8570.58
501_L517_C0.8570.58
406_C415_L0.8560.58
216_V347_G0.8540.58
598_F669_H0.8520.58
210_L314_L0.8490.57
31_Q170_L0.8490.57
146_Y178_P0.8470.57
471_Q738_A0.8430.57
392_P447_Q0.8410.57
9_V78_P0.8410.57
708_L711_Y0.8400.57
126_Y129_I0.8400.57
373_R378_V0.8400.57
373_R417_Q0.8370.56
334_N348_F0.8360.56
409_R442_Y0.8360.56
482_A723_L0.8350.56
501_L547_W0.8350.56
664_R667_A0.8340.56
604_A651_W0.8340.56
496_V500_T0.8340.56
123_R171_D0.8330.56
559_P562_Q0.8320.56
393_P444_F0.8300.56
498_A695_S0.8290.56
474_L508_E0.8280.55
243_K402_K0.8270.55
394_V448_Y0.8260.55
709_A713_A0.8260.55
201_A204_Q0.8240.55
160_P635_P0.8230.55
458_V461_Q0.8220.55
314_L317_P0.8210.55
584_R587_N0.8200.55
397_L451_H0.8200.55
65_C74_V0.8190.55
529_G645_L0.8170.54
281_K284_P0.8170.54
214_K347_G0.8160.54
404_T418_H0.8150.54
139_T221_I0.8140.54
531_L675_G0.8130.54
121_E179_V0.8120.54
128_F352_N0.8120.54
537_P589_P0.8120.54
393_P447_Q0.8110.54
191_V195_E0.8110.54
30_A57_F0.8090.54
219_K334_N0.8090.54
541_L718_L0.8090.54
234_N238_T0.8090.54
542_A589_P0.8060.53
45_G180_A0.8050.53
153_M353_R0.8040.53
673_A708_L0.8030.53
571_Q574_N0.8020.53
333_S336_Q0.7990.53
25_F29_L0.7970.53
497_I680_M0.7950.52
221_I374_S0.7950.52
237_A241_A0.7940.52
489_W693_V0.7940.52
417_Q430_Q0.7940.52
481_A736_V0.7930.52
601_V668_F0.7930.52
636_V678_A0.7920.52
497_I519_R0.7900.52
605_L664_R0.7900.52
153_M178_P0.7900.52
56_T59_V0.7890.52
25_F65_C0.7870.52
8_G81_W0.7860.52
295_N627_A0.7840.51
58_L61_L0.7820.51
257_A269_T0.7810.51
311_L317_P0.7810.51
578_L731_S0.7780.51
549_N553_Q0.7770.51
695_S729_G0.7760.51
400_D698_V0.7760.51
113_L273_A0.7750.51
142_R152_V0.7730.50
464_R470_T0.7700.50
255_P315_Q0.7700.50
139_T228_C0.7660.50
459_S481_A0.7660.50
405_F431_W0.7650.50
45_G100_T0.7650.50
125_R201_A0.7640.50
231_R316_C0.7640.50
233_S288_D0.7640.50
404_T416_S0.7630.49
555_L582_I0.7630.49
31_Q87_E0.7610.49
117_N308_H0.7600.49
25_F64_H0.7590.49
535_A552_A0.7580.49
680_M684_A0.7570.49
692_L712_L0.7570.49
273_A302_P0.7560.49
365_R623_E0.7560.49
594_C664_R0.7550.49
9_V58_L0.7540.49
13_I71_I0.7520.48
279_D295_N0.7510.48
243_K248_K0.7510.48
393_P408_V0.7510.48
419_L434_A0.7500.48
520_V525_C0.7470.48
195_E338_L0.7470.48
50_L61_L0.7470.48
541_L544_K0.7460.48
406_C547_W0.7450.48
103_V140_I0.7440.48
430_Q433_E0.7430.48
407_L444_F0.7430.48
337_A345_A0.7410.47
334_N337_A0.7400.47
390_N408_V0.7400.47
535_A590_L0.7400.47
258_D432_R0.7400.47
188_L202_A0.7390.47
699_I705_R0.7390.47
334_N417_Q0.7380.47
626_A673_A0.7370.47
143_A440_N0.7360.47
532_P647_L0.7350.47
294_L620_C0.7350.47
13_I543_A0.7350.47
671_A675_G0.7340.47
501_L672_L0.7340.47
501_L698_V0.7330.47
403_N419_L0.7330.47
42_D47_E0.7320.47
436_R439_Q0.7320.47
477_H520_V0.7310.47
461_Q465_E0.7310.47
424_D458_V0.7300.46
482_A487_H0.7300.46
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577_V580_R0.7050.44
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399_A729_G0.7040.44
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191_V334_N0.7010.44
254_L278_V0.7010.44
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233_S237_A0.6980.44
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204_Q313_E0.6960.43
33_L64_H0.6960.43
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70_R224_F0.6950.43
549_N591_A0.6950.43
332_I430_Q0.6940.43
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394_V450_V0.6890.43
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431_W435_L0.6850.42
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564_Y567_T0.6790.42
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515_G623_E0.6650.41
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665_A673_A0.6630.40
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168_D710_H0.6610.40
123_R179_V0.6600.40
247_A621_A0.6600.40
221_I487_H0.6580.40
183_E352_N0.6580.40
605_L626_A0.6580.40
103_V144_M0.6570.40
68_L132_T0.6570.40
294_L621_A0.6570.40
128_F305_P0.6560.40
207_I310_L0.6550.40
139_T363_V0.6550.40
146_Y153_M0.6530.40
435_L439_Q0.6520.39
90_I177_Q0.6520.39
12_R106_A0.6500.39
709_A717_L0.6490.39
489_W691_T0.6490.39
178_P225_H0.6490.39
480_A483_C0.6480.39
144_M434_A0.6470.39
266_Q399_A0.6470.39
51_R81_W0.6470.39
68_L133_H0.6440.39
356_V680_M0.6440.39
358_R589_P0.6440.39
557_F651_W0.6430.39
374_S720_P0.6420.39
519_R526_E0.6410.38
612_L617_E0.6390.38
670_D703_L0.6370.38
243_K421_D0.6370.38
351_H546_P0.6360.38
598_F704_L0.6350.38
439_Q445_T0.6350.38
417_Q438_M0.6340.38
396_C735_G0.6340.38
302_P536_L0.6340.38
481_A525_C0.6340.38
26_V678_A0.6330.38
228_C235_A0.6310.38
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547_W574_N0.6310.38
16_K380_D0.6300.37
581_A584_R0.6290.37
554_C604_A0.6290.37
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677_A684_A0.6280.37
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25_F62_Y0.6260.37
190_W197_A0.6260.37
253_M303_A0.6260.37
484_L575_W0.6260.37
429_M432_R0.6250.37
106_A133_H0.6240.37
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187_H199_Q0.6210.37
373_R405_F0.6210.37
328_K424_D0.6200.37
143_A356_V0.6200.37
684_A689_I0.6200.37
555_L583_E0.6190.37
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130_N695_S0.6190.37
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320_M424_D0.6080.36
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627_A634_H0.6040.35
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437_L442_Y0.6030.35
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580_R583_E0.6010.35
650_F653_Q0.6000.35
177_Q403_N0.6000.35
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192_S201_A0.5980.35
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430_Q486_E0.5940.34
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359_M374_S0.5930.34
474_L509_N0.5930.34
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90_I225_H0.5930.34
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157_P163_D0.5920.34
575_W579_A0.5920.34
381_A669_H0.5910.34
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268_L278_V0.5840.34
167_R179_V0.5840.34
600_A647_L0.5840.34
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50_L65_C0.5840.34
337_A344_I0.5830.34
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214_K346_D0.5830.34
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616_G700_H0.5810.33
299_V327_G0.5800.33
545_Q574_N0.5790.33
647_L672_L0.5790.33
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370_M723_L0.5730.33
327_G531_L0.5730.33
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154_A723_L0.5710.33
58_L62_Y0.5710.33
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694_F705_R0.5710.33
177_Q180_A0.5700.32
396_C730_L0.5700.32
309_L418_H0.5700.32
100_T106_A0.5700.32
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541_L548_R0.5600.32
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564_Y575_W0.5590.32
121_E271_P0.5590.32
102_I347_G0.5590.32
651_W654_W0.5590.32
165_E171_D0.5580.32
117_N470_T0.5580.32
666_W703_L0.5580.32
228_C311_L0.5570.31
42_D291_A0.5570.31
629_C663_Q0.5560.31
236_V288_D0.5560.31
330_P430_Q0.5560.31
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281_K577_V0.5540.31
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326_S402_K0.5540.31
294_L700_H0.5540.31
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457_Y577_V0.5540.31
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319_V589_P0.5530.31
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130_N146_Y0.5500.31
396_C450_V0.5500.31
625_L662_N0.5490.31
501_L694_F0.5490.31
403_N545_Q0.5480.31
174_F553_Q0.5480.31
286_L680_M0.5480.31
582_I740_A0.5480.31
281_K319_V0.5470.31
499_L559_P0.5470.31
474_L525_C0.5470.31
499_L708_L0.5460.31
400_D456_G0.5460.31
571_Q575_W0.5460.31
15_G18_Q0.5450.30
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224_F477_H0.5450.30
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250_L448_Y0.5440.30
33_L50_L0.5440.30
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619_A669_H0.5430.30
152_V354_D0.5430.30
68_L552_A0.5430.30
689_I715_F0.5430.30
45_G68_L0.5430.30
547_W551_L0.5420.30
278_V366_E0.5420.30
483_C737_I0.5420.30
179_V499_L0.5420.30
613_S617_E0.5400.30
311_L323_G0.5400.30
708_L712_L0.5390.30
43_G133_H0.5390.30
15_G19_G0.5390.30
311_L318_L0.5390.30
207_I316_C0.5380.30
8_G52_E0.5380.30
415_L565_S0.5380.30
605_L634_H0.5380.30
520_V695_S0.5370.30
16_K286_L0.5370.30
152_V431_W0.5370.30
121_E171_D0.5370.30
218_I320_M0.5370.30
419_L430_Q0.5360.30
450_V737_I0.5360.30
417_Q434_A0.5360.30
211_K315_Q0.5360.30
570_V574_N0.5360.30
640_R686_M0.5360.30
645_L679_L0.5350.30
163_D194_G0.5350.30
178_P498_A0.5350.30
130_N402_K0.5350.30
29_L32_Q0.5350.30
102_I735_G0.5340.30
50_L57_F0.5340.30
511_A590_L0.5330.30
707_R710_H0.5320.29
290_I651_W0.5320.29
48_V57_F0.5320.29
607_C661_V0.5310.29
45_G179_V0.5310.29
369_E719_F0.5310.29
418_H430_Q0.5300.29
347_G656_N0.5300.29
534_V647_L0.5290.29
647_L675_G0.5290.29
622_L665_A0.5290.29
522_Y736_V0.5280.29
246_P250_L0.5280.29
24_P41_N0.5280.29
432_R436_R0.5280.29
270_T469_P0.5270.29
496_V593_S0.5270.29
103_V106_A0.5270.29
174_F417_Q0.5270.29
381_A442_Y0.5270.29
45_G133_H0.5270.29
442_Y581_A0.5260.29
292_P546_P0.5260.29
581_A588_A0.5260.29
255_P707_R0.5250.29
190_W195_E0.5250.29
504_I540_D0.5250.29
126_Y589_P0.5250.29
550_L651_W0.5250.29
155_A335_E0.5240.29
305_P396_C0.5240.29
67_P292_P0.5240.29
563_N567_T0.5240.29
535_A549_N0.5230.29
623_E627_A0.5230.29
636_V649_T0.5230.29
44_D221_I0.5230.29
93_S665_A0.5230.29
110_P269_T0.5220.29
115_E281_K0.5220.29
26_V48_V0.5220.29
422_L435_L0.5210.29
38_D79_F0.5200.29
102_I154_A0.5190.28
254_L317_P0.5190.28
180_A345_A0.5190.28
177_Q225_H0.5190.28
48_V323_G0.5190.28
130_N180_A0.5190.28
197_A200_E0.5180.28
252_V564_Y0.5180.28
413_A536_L0.5180.28
18_Q24_P0.5180.28
639_P646_D0.5170.28
108_T225_H0.5170.28
659_A667_A0.5160.28
494_G690_T0.5160.28
25_F377_Y0.5160.28
551_L679_L0.5160.28
402_K668_F0.5160.28
130_N179_V0.5160.28
91_R302_P0.5140.28
139_T381_A0.5140.28
188_L199_Q0.5130.28
177_Q484_L0.5130.28
494_G691_T0.5130.28
728_G738_A0.5130.28
350_I354_D0.5130.28
69_A384_L0.5120.28
512_L543_A0.5120.28
484_L493_G0.5110.28
180_A486_E0.5110.28
208_A713_A0.5110.28
295_N731_S0.5100.28
536_L600_A0.5100.28
307_Q431_W0.5100.28
515_G672_L0.5100.28
225_H359_M0.5100.28
130_N483_C0.5100.28
669_H712_L0.5100.28
634_H640_R0.5090.28
699_I704_L0.5090.28
629_C662_N0.5080.28
179_V378_V0.5080.28
273_A397_L0.5080.28
374_S381_A0.5080.28
533_A591_A0.5070.28
54_P363_V0.5070.28
602_A618_A0.5060.28
241_A265_R0.5060.28
220_G307_Q0.5060.28
433_E464_R0.5060.28
115_E649_T0.5060.28
357_Q434_A0.5050.27
381_A474_L0.5050.27
304_N530_G0.5050.27
634_H654_W0.5050.27
20_V23_R0.5050.27
152_V357_Q0.5050.27
307_Q351_H0.5040.27
441_I607_C0.5040.27
246_P417_Q0.5040.27
254_L363_V0.5040.27
246_P442_Y0.5040.27
16_K101_Q0.5030.27
302_P326_S0.5020.27
550_L557_F0.5020.27
179_V365_R0.5020.27
547_W603_A0.5020.27
290_I678_A0.5020.27
17_V23_R0.5010.27
203_L207_I0.5010.27
272_A377_Y0.5010.27
263_A368_G0.5010.27
709_A719_F0.5010.27
13_I62_Y0.5010.27
582_I619_A0.5000.27
532_P648_A0.5000.27
515_G698_V0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3vthA 1 0.976 100 0.237 Contact Map
4g9iA 1 0.972 100 0.25 Contact Map
3ttcA 1 0.8587 100 0.313 Contact Map
3enoA 1 0.3773 100 0.868 Contact Map
1k7jA 1 0.2573 100 0.871 Contact Map
1jcuA 1 0.2613 100 0.872 Contact Map
2ivnA 1 0.3707 100 0.872 Contact Map
4k25A 2 0.368 100 0.873 Contact Map
2eqaA 1 0.4013 100 0.874 Contact Map
3zeuB 1 0.3787 100 0.88 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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