HYPF - ECOLI - GREMLIN Contacts

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HYPF - Carbamoyltransferase HypF

UniProt:	P30131	Sequences: MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGDGVEVRLREDPETFLVQLYQHCPPLARIDSVEREPFIWSQLPTEFTIRQSTGGTMNTQIVPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCPACDKEYRDPLDRRFHAQPVACPECGPHLEWVSHGEHAEQEAALQAAIAQLKMGKIVAIKGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIVLVDKKYVPELCDDIAPDLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISNEQALADLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALALPPGFKNVPPVLCLGADLKNTFCLVRGEQAVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTPQYVVHDAHPGYVSSQWAREMNLPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPEWQNYSETASVQQQNWSVLARAIERGINAPLASSCGRFFDAVAAALGCAPATLSYEGEAACALEALAASCHGVTHPVTMPRVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMREQATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAARWLAGEVQNG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11551
Length:	750 (725)
Sequences:	1338 (1088)
Seq/√Len:	40.4

ECOLI - HYPF

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
480_A	498_A	5.107	1.00
116_M	129_I	5.054	1.00
163_D	167_R	4.702	1.00
480_A	500_T	4.659	1.00
221_I	304_N	4.473	1.00
233_S	287_C	4.219	1.00
26_V	61_L	4.016	1.00
508_E	525_C	4.004	1.00
264_A	279_D	3.878	1.00
35_L	50_L	3.875	1.00
152_V	356_V	3.809	1.00
111_A	133_H	3.534	1.00
399_A	730_L	3.516	1.00
115_E	129_I	3.362	1.00
233_S	289_D	3.347	1.00
60_Q	64_H	3.329	1.00
224_F	334_N	3.323	1.00
673_A	707_R	3.306	1.00
450_V	738_A	3.257	1.00
406_C	413_A	3.232	1.00
229_D	232_N	3.223	1.00
511_A	533_A	3.221	1.00
130_N	178_P	3.135	1.00
142_R	154_A	3.115	1.00
51_R	84_L	3.110	1.00
209_Q	347_G	3.104	1.00
227_A	320_M	3.093	1.00
451_H	463_A	3.058	1.00
422_L	459_S	3.051	1.00
161_A	183_E	3.027	1.00
33_L	60_Q	2.938	1.00
617_E	621_A	2.928	1.00
190_W	347_G	2.903	1.00
451_H	472_T	2.853	1.00
209_Q	214_K	2.837	1.00
247_A	617_E	2.781	1.00
684_A	715_F	2.773	1.00
357_Q	437_L	2.735	1.00
260_L	278_V	2.724	1.00
723_L	732_L	2.698	1.00
700_H	726_G	2.681	1.00
32_Q	60_Q	2.651	1.00
481_A	737_I	2.638	1.00
238_T	241_A	2.624	1.00
540_D	543_A	2.607	1.00
532_P	646_D	2.606	1.00
334_N	350_I	2.596	1.00
139_T	359_M	2.574	1.00
238_T	242_R	2.555	1.00
8_G	49_R	2.551	1.00
626_A	703_L	2.519	1.00
534_V	553_Q	2.483	1.00
408_V	735_G	2.442	1.00
489_W	718_L	2.425	1.00
117_N	312_Q	2.421	1.00
501_L	676_F	2.420	1.00
484_L	489_W	2.414	1.00
254_L	299_V	2.408	1.00
404_T	731_S	2.405	1.00
601_V	654_W	2.393	1.00
68_L	106_A	2.345	1.00
499_L	517_C	2.343	1.00
155_A	354_D	2.323	1.00
499_L	680_M	2.309	1.00
206_A	216_V	2.303	1.00
531_L	594_C	2.302	1.00
225_H	303_A	2.289	1.00
480_A	520_V	2.256	1.00
415_L	731_S	2.241	1.00
519_R	689_I	2.235	1.00
123_R	165_E	2.230	1.00
108_T	308_H	2.218	1.00
190_W	209_Q	2.204	0.99
451_H	470_T	2.184	0.99
218_I	227_A	2.168	0.99
199_Q	202_A	2.152	0.99
483_C	720_P	2.149	0.99
113_L	308_H	2.124	0.99
125_R	313_E	2.109	0.99
645_L	675_G	2.096	0.99
607_C	625_L	2.092	0.99
477_H	737_I	2.087	0.99
191_V	338_L	2.069	0.99
464_R	472_T	2.050	0.99
676_F	708_L	2.048	0.99
677_A	711_Y	2.046	0.99
12_R	42_D	2.045	0.99
594_C	672_L	2.041	0.99
406_C	731_S	2.037	0.99
530_G	533_A	2.028	0.99
723_L	729_G	1.999	0.99
495_D	521_N	1.996	0.99
328_K	340_D	1.993	0.99
500_T	520_V	1.955	0.99
8_G	51_R	1.937	0.99
453_A	508_E	1.911	0.99
608_A	621_A	1.911	0.99
603_A	609_P	1.892	0.98
111_A	114_A	1.881	0.98
483_C	693_V	1.866	0.98
695_S	720_P	1.862	0.98
32_Q	64_H	1.850	0.98
504_I	512_L	1.845	0.98
36_H	87_E	1.825	0.98
477_H	481_A	1.802	0.98
456_G	461_Q	1.798	0.98
487_H	720_P	1.796	0.98
323_G	331_A	1.790	0.98
8_G	85_P	1.778	0.98
499_L	676_F	1.777	0.98
257_A	265_R	1.772	0.98
485_A	732_L	1.770	0.98
187_H	352_N	1.764	0.98
323_G	337_A	1.758	0.97
614_Y	620_C	1.756	0.97
536_L	549_N	1.735	0.97
261_P	264_A	1.734	0.97
484_L	693_V	1.729	0.97
296_E	365_R	1.715	0.97
334_N	354_D	1.712	0.97
415_L	723_L	1.706	0.97
323_G	348_F	1.705	0.97
287_C	290_I	1.702	0.97
517_C	679_L	1.693	0.97
286_L	290_I	1.684	0.97
405_F	435_L	1.684	0.97
384_L	413_A	1.683	0.97
614_Y	621_A	1.681	0.97
431_W	462_W	1.678	0.97
626_A	665_A	1.676	0.97
528_L	683_Q	1.674	0.97
118_T	121_E	1.631	0.96
484_L	496_V	1.614	0.96
138_F	438_M	1.608	0.96
674_Q	711_Y	1.604	0.96
654_W	664_R	1.601	0.96
14_R	73_S	1.590	0.95
406_C	735_G	1.574	0.95
541_L	545_Q	1.571	0.95
142_R	356_V	1.559	0.95
192_S	195_E	1.549	0.95
264_A	366_E	1.547	0.95
519_R	528_L	1.546	0.95
413_A	732_L	1.541	0.95
501_L	594_C	1.538	0.94
262_D	265_R	1.534	0.94
38_D	91_R	1.534	0.94
485_A	736_V	1.534	0.94
11_L	48_V	1.528	0.94
192_S	196_H	1.521	0.94
673_A	711_Y	1.519	0.94
418_H	728_G	1.514	0.94
451_H	460_S	1.514	0.94
518_L	525_C	1.513	0.94
205_A	208_A	1.502	0.94
38_D	49_R	1.501	0.94
246_P	613_S	1.501	0.94
482_A	729_G	1.496	0.94
684_A	690_T	1.496	0.94
659_A	663_Q	1.495	0.94
11_L	58_L	1.494	0.94
373_R	381_A	1.490	0.93
699_I	708_L	1.486	0.93
482_A	720_P	1.482	0.93
405_F	438_M	1.475	0.93
40_C	47_E	1.463	0.93
237_A	289_D	1.461	0.93
236_V	287_C	1.455	0.93
267_L	377_Y	1.454	0.93
189_E	350_I	1.454	0.93
724_P	728_G	1.444	0.92
242_R	346_D	1.437	0.92
197_A	202_A	1.437	0.92
125_R	200_E	1.429	0.92
529_G	679_L	1.421	0.92
114_A	121_E	1.417	0.92
265_R	269_T	1.416	0.92
13_I	48_V	1.415	0.92
545_Q	611_T	1.404	0.91
207_I	314_L	1.404	0.91
49_R	85_P	1.403	0.91
694_F	717_L	1.403	0.91
400_D	458_V	1.401	0.91
487_H	721_Q	1.401	0.91
188_L	203_L	1.396	0.91
534_V	549_N	1.396	0.91
397_L	462_W	1.394	0.91
138_F	434_A	1.391	0.91
226_L	345_A	1.388	0.91
598_F	668_F	1.382	0.91
263_A	266_Q	1.380	0.91
364_V	377_Y	1.375	0.90
364_V	370_M	1.371	0.90
462_W	466_M	1.371	0.90
232_N	235_A	1.367	0.90
486_E	720_P	1.367	0.90
224_F	350_I	1.366	0.90
242_R	344_I	1.352	0.90
246_P	327_G	1.352	0.90
252_V	297_V	1.349	0.89
553_Q	600_A	1.342	0.89
480_A	695_S	1.341	0.89
16_K	103_V	1.341	0.89
403_N	431_W	1.335	0.89
115_E	121_E	1.325	0.89
460_S	472_T	1.324	0.89
477_H	518_L	1.316	0.88
210_L	227_A	1.314	0.88
533_A	592_S	1.312	0.88
483_C	695_S	1.303	0.88
395_L	435_L	1.302	0.88
164_K	168_D	1.298	0.88
517_C	683_Q	1.296	0.87
409_R	412_Q	1.296	0.87
65_C	69_A	1.289	0.87
225_H	320_M	1.289	0.87
27_W	169_P	1.284	0.87
168_D	171_D	1.284	0.87
337_A	348_F	1.283	0.87
450_V	472_T	1.280	0.87
121_E	129_I	1.280	0.87
33_L	56_T	1.275	0.87
517_C	676_F	1.275	0.87
397_L	463_A	1.266	0.86
391_V	739_A	1.260	0.86
397_L	431_W	1.258	0.86
385_P	522_Y	1.256	0.86
646_D	649_T	1.255	0.86
673_A	703_L	1.254	0.86
581_A	587_N	1.248	0.85
27_W	174_F	1.247	0.85
256_V	259_G	1.240	0.85
14_R	75_E	1.238	0.85
252_V	299_V	1.233	0.85
504_I	543_A	1.225	0.84
40_C	91_R	1.224	0.84
400_D	423_S	1.222	0.84
428_Q	458_V	1.219	0.84
432_R	465_E	1.219	0.84
605_L	622_L	1.216	0.84
480_A	496_V	1.211	0.84
10_Q	77_E	1.210	0.84
121_E	165_E	1.203	0.83
382_L	732_L	1.200	0.83
477_H	525_C	1.194	0.83
405_F	416_S	1.192	0.83
453_A	474_L	1.190	0.83
693_V	718_L	1.190	0.83
550_L	604_A	1.188	0.82
486_E	722_S	1.186	0.82
480_A	693_V	1.179	0.82
448_Y	471_Q	1.179	0.82
497_I	528_L	1.178	0.82
132_T	178_P	1.177	0.82
189_E	334_N	1.176	0.82
242_R	345_A	1.175	0.82
250_L	290_I	1.175	0.82
401_L	615_E	1.174	0.82
532_P	556_R	1.174	0.82
253_M	311_L	1.173	0.82
71_I	74_V	1.169	0.81
367_S	713_A	1.167	0.81
36_H	85_P	1.166	0.81
602_A	608_A	1.164	0.81
42_D	100_T	1.149	0.80
423_S	458_V	1.147	0.80
537_P	582_I	1.142	0.80
163_D	179_V	1.139	0.80
210_L	318_L	1.138	0.80
28_Q	32_Q	1.137	0.80
110_P	273_A	1.137	0.80
629_C	666_W	1.136	0.79
208_A	212_M	1.136	0.79
497_I	517_C	1.134	0.79
529_G	675_G	1.134	0.79
394_V	735_G	1.132	0.79
424_D	427_I	1.131	0.79
9_V	76_R	1.131	0.79
449_V	466_M	1.130	0.79
11_L	76_R	1.129	0.79
691_T	716_T	1.128	0.79
102_I	441_I	1.126	0.79
496_V	693_V	1.126	0.79
597_F	668_F	1.125	0.79
267_L	276_V	1.123	0.79
8_G	79_F	1.120	0.79
27_W	170_L	1.120	0.79
198_E	202_A	1.112	0.78
252_V	300_M	1.112	0.78
480_A	484_L	1.110	0.78
703_L	707_R	1.109	0.78
551_L	579_A	1.105	0.78
56_T	60_Q	1.105	0.78
272_A	380_D	1.102	0.77
205_A	209_Q	1.099	0.77
605_L	665_A	1.096	0.77
383_A	411_E	1.094	0.77
414_V	442_Y	1.092	0.77
448_Y	469_P	1.090	0.77
202_A	349_L	1.090	0.77
149_P	177_Q	1.088	0.76
36_H	51_R	1.086	0.76
138_F	405_F	1.085	0.76
691_T	718_L	1.082	0.76
127_P	188_L	1.081	0.76
369_E	725_A	1.079	0.76
206_A	218_I	1.071	0.75
108_T	113_L	1.071	0.75
336_Q	340_D	1.070	0.75
601_V	664_R	1.069	0.75
473_V	737_I	1.065	0.75
402_K	615_E	1.065	0.75
58_L	76_R	1.062	0.75
27_W	31_Q	1.059	0.74
358_R	430_Q	1.059	0.74
49_R	79_F	1.057	0.74
670_D	707_R	1.055	0.74
450_V	473_V	1.054	0.74
107_A	273_A	1.053	0.74
451_H	469_P	1.051	0.74
328_K	426_G	1.048	0.74
218_I	225_H	1.046	0.74
304_N	307_Q	1.039	0.73
10_Q	47_E	1.038	0.73
607_C	621_A	1.038	0.73
206_A	310_L	1.037	0.73
188_L	306_L	1.033	0.73
635_P	653_Q	1.032	0.73
365_R	702_R	1.032	0.73
712_L	717_L	1.031	0.72
498_A	693_V	1.031	0.72
724_P	729_G	1.030	0.72
59_V	63_Q	1.027	0.72
207_I	313_E	1.023	0.72
117_N	125_R	1.023	0.72
483_C	487_H	1.023	0.72
450_V	471_Q	1.019	0.72
400_D	506_M	1.016	0.71
535_A	592_S	1.015	0.71
314_L	318_L	1.009	0.71
484_L	718_L	1.007	0.71
50_L	71_I	1.002	0.70
191_V	350_I	1.000	0.70
397_L	449_V	0.998	0.70
580_R	584_R	0.993	0.70
341_L	344_I	0.993	0.70
104_P	177_Q	0.993	0.70
435_L	462_W	0.991	0.69
42_D	45_G	0.990	0.69
122_R	161_A	0.990	0.69
118_T	124_Y	0.986	0.69
438_M	442_Y	0.981	0.69
35_L	52_E	0.981	0.69
295_N	624_A	0.979	0.68
628_S	662_N	0.978	0.68
395_L	449_V	0.976	0.68
647_L	650_F	0.971	0.68
303_A	307_Q	0.971	0.68
247_A	613_S	0.970	0.68
160_P	183_E	0.969	0.68
517_C	529_G	0.967	0.68
337_A	341_L	0.965	0.67
260_L	265_R	0.961	0.67
333_S	354_D	0.957	0.67
634_H	667_A	0.956	0.67
712_L	715_F	0.955	0.67
555_L	579_A	0.954	0.66
553_Q	651_W	0.953	0.66
702_R	706_A	0.944	0.66
273_A	308_H	0.942	0.65
143_A	150_F	0.941	0.65
11_L	74_V	0.941	0.65
331_A	340_D	0.941	0.65
405_F	434_A	0.939	0.65
569_S	609_P	0.938	0.65
667_A	671_A	0.937	0.65
209_Q	216_V	0.935	0.65
13_I	74_V	0.935	0.65
242_R	341_L	0.928	0.64
253_M	320_M	0.928	0.64
634_H	638_M	0.925	0.64
142_R	354_D	0.922	0.64
100_T	133_H	0.921	0.64
215_I	344_I	0.920	0.64
485_A	723_L	0.920	0.64
10_Q	49_R	0.919	0.64
634_H	664_R	0.918	0.63
116_M	121_E	0.916	0.63
636_V	671_A	0.913	0.63
720_P	725_A	0.912	0.63
123_R	129_I	0.912	0.63
401_L	421_D	0.912	0.63
160_P	163_D	0.912	0.63
457_Y	504_I	0.911	0.63
12_R	47_E	0.910	0.63
423_S	540_D	0.909	0.63
382_L	485_A	0.908	0.63
409_R	414_V	0.903	0.62
278_V	299_V	0.902	0.62
626_A	629_C	0.898	0.62
397_L	459_S	0.896	0.62
161_A	164_K	0.896	0.62
620_C	698_V	0.896	0.62
358_R	735_G	0.895	0.61
338_L	350_I	0.895	0.61
663_Q	667_A	0.894	0.61
206_A	347_G	0.893	0.61
582_I	588_A	0.893	0.61
549_N	552_A	0.893	0.61
119_P	124_Y	0.892	0.61
654_W	671_A	0.890	0.61
669_H	703_L	0.886	0.61
124_Y	127_P	0.882	0.60
277_L	296_E	0.882	0.60
294_L	614_Y	0.882	0.60
358_R	433_E	0.881	0.60
460_S	464_R	0.879	0.60
720_P	723_L	0.877	0.60
612_L	618_A	0.877	0.60
101_Q	381_A	0.875	0.60
577_V	581_A	0.872	0.59
345_A	348_F	0.871	0.59
693_V	720_P	0.871	0.59
707_R	711_Y	0.870	0.59
625_L	661_V	0.869	0.59
158_L	179_V	0.869	0.59
228_C	319_V	0.868	0.59
694_F	712_L	0.865	0.59
397_L	435_L	0.864	0.59
51_R	85_P	0.860	0.58
436_R	440_N	0.860	0.58
413_A	735_G	0.858	0.58
220_G	303_A	0.857	0.58
501_L	517_C	0.857	0.58
406_C	415_L	0.856	0.58
216_V	347_G	0.854	0.58
598_F	669_H	0.852	0.58
210_L	314_L	0.849	0.57
31_Q	170_L	0.849	0.57
146_Y	178_P	0.847	0.57
471_Q	738_A	0.843	0.57
392_P	447_Q	0.841	0.57
9_V	78_P	0.841	0.57
708_L	711_Y	0.840	0.57
126_Y	129_I	0.840	0.57
373_R	378_V	0.840	0.57
373_R	417_Q	0.837	0.56
334_N	348_F	0.836	0.56
409_R	442_Y	0.836	0.56
482_A	723_L	0.835	0.56
501_L	547_W	0.835	0.56
664_R	667_A	0.834	0.56
604_A	651_W	0.834	0.56
496_V	500_T	0.834	0.56
123_R	171_D	0.833	0.56
559_P	562_Q	0.832	0.56
393_P	444_F	0.830	0.56
498_A	695_S	0.829	0.56
474_L	508_E	0.828	0.55
243_K	402_K	0.827	0.55
394_V	448_Y	0.826	0.55
709_A	713_A	0.826	0.55
201_A	204_Q	0.824	0.55
160_P	635_P	0.823	0.55
458_V	461_Q	0.822	0.55
314_L	317_P	0.821	0.55
584_R	587_N	0.820	0.55
397_L	451_H	0.820	0.55
65_C	74_V	0.819	0.55
529_G	645_L	0.817	0.54
281_K	284_P	0.817	0.54
214_K	347_G	0.816	0.54
404_T	418_H	0.815	0.54
139_T	221_I	0.814	0.54
531_L	675_G	0.813	0.54
121_E	179_V	0.812	0.54
128_F	352_N	0.812	0.54
537_P	589_P	0.812	0.54
393_P	447_Q	0.811	0.54
191_V	195_E	0.811	0.54
30_A	57_F	0.809	0.54
219_K	334_N	0.809	0.54
541_L	718_L	0.809	0.54
234_N	238_T	0.809	0.54
542_A	589_P	0.806	0.53
45_G	180_A	0.805	0.53
153_M	353_R	0.804	0.53
673_A	708_L	0.803	0.53
571_Q	574_N	0.802	0.53
333_S	336_Q	0.799	0.53
25_F	29_L	0.797	0.53
497_I	680_M	0.795	0.52
221_I	374_S	0.795	0.52
237_A	241_A	0.794	0.52
489_W	693_V	0.794	0.52
417_Q	430_Q	0.794	0.52
481_A	736_V	0.793	0.52
601_V	668_F	0.793	0.52
636_V	678_A	0.792	0.52
497_I	519_R	0.790	0.52
605_L	664_R	0.790	0.52
153_M	178_P	0.790	0.52
56_T	59_V	0.789	0.52
25_F	65_C	0.787	0.52
8_G	81_W	0.786	0.52
295_N	627_A	0.784	0.51
58_L	61_L	0.782	0.51
257_A	269_T	0.781	0.51
311_L	317_P	0.781	0.51
578_L	731_S	0.778	0.51
549_N	553_Q	0.777	0.51
695_S	729_G	0.776	0.51
400_D	698_V	0.776	0.51
113_L	273_A	0.775	0.51
142_R	152_V	0.773	0.50
464_R	470_T	0.770	0.50
255_P	315_Q	0.770	0.50
139_T	228_C	0.766	0.50
459_S	481_A	0.766	0.50
405_F	431_W	0.765	0.50
45_G	100_T	0.765	0.50
125_R	201_A	0.764	0.50
231_R	316_C	0.764	0.50
233_S	288_D	0.764	0.50
404_T	416_S	0.763	0.49
555_L	582_I	0.763	0.49
31_Q	87_E	0.761	0.49
117_N	308_H	0.760	0.49
25_F	64_H	0.759	0.49
535_A	552_A	0.758	0.49
680_M	684_A	0.757	0.49
692_L	712_L	0.757	0.49
273_A	302_P	0.756	0.49
365_R	623_E	0.756	0.49
594_C	664_R	0.755	0.49
9_V	58_L	0.754	0.49
13_I	71_I	0.752	0.48
279_D	295_N	0.751	0.48
243_K	248_K	0.751	0.48
393_P	408_V	0.751	0.48
419_L	434_A	0.750	0.48
520_V	525_C	0.747	0.48
195_E	338_L	0.747	0.48
50_L	61_L	0.747	0.48
541_L	544_K	0.746	0.48
406_C	547_W	0.745	0.48
103_V	140_I	0.744	0.48
430_Q	433_E	0.743	0.48
407_L	444_F	0.743	0.48
337_A	345_A	0.741	0.47
334_N	337_A	0.740	0.47
390_N	408_V	0.740	0.47
535_A	590_L	0.740	0.47
258_D	432_R	0.740	0.47
188_L	202_A	0.739	0.47
699_I	705_R	0.739	0.47
334_N	417_Q	0.738	0.47
626_A	673_A	0.737	0.47
143_A	440_N	0.736	0.47
532_P	647_L	0.735	0.47
294_L	620_C	0.735	0.47
13_I	543_A	0.735	0.47
671_A	675_G	0.734	0.47
501_L	672_L	0.734	0.47
501_L	698_V	0.733	0.47
403_N	419_L	0.733	0.47
42_D	47_E	0.732	0.47
436_R	439_Q	0.732	0.47
477_H	520_V	0.731	0.47
461_Q	465_E	0.731	0.47
424_D	458_V	0.730	0.46
482_A	487_H	0.730	0.46
594_C	699_I	0.728	0.46
680_M	692_L	0.728	0.46
532_P	649_T	0.728	0.46
357_Q	417_Q	0.727	0.46
481_A	522_Y	0.726	0.46
501_L	708_L	0.726	0.46
8_G	38_D	0.725	0.46
418_H	731_S	0.724	0.46
598_F	618_A	0.723	0.46
600_A	651_W	0.722	0.46
327_G	340_D	0.720	0.46
330_P	620_C	0.720	0.46
279_D	366_E	0.719	0.45
98_M	144_M	0.717	0.45
495_D	519_R	0.714	0.45
385_P	488_Q	0.714	0.45
217_A	341_L	0.713	0.45
126_Y	306_L	0.713	0.45
535_A	585_G	0.712	0.45
125_R	312_Q	0.711	0.45
408_V	413_A	0.711	0.45
138_F	417_Q	0.710	0.45
680_M	708_L	0.708	0.44
713_A	717_L	0.706	0.44
577_V	580_R	0.705	0.44
11_L	50_L	0.705	0.44
417_Q	725_A	0.705	0.44
399_A	729_G	0.704	0.44
101_Q	414_V	0.704	0.44
191_V	334_N	0.701	0.44
254_L	278_V	0.701	0.44
267_L	364_V	0.699	0.44
549_N	600_A	0.699	0.44
104_P	380_D	0.698	0.44
547_W	570_V	0.698	0.44
594_C	676_F	0.698	0.44
233_S	237_A	0.698	0.44
367_S	706_A	0.697	0.43
204_Q	313_E	0.696	0.43
33_L	64_H	0.696	0.43
453_A	472_T	0.696	0.43
70_R	224_F	0.695	0.43
549_N	591_A	0.695	0.43
332_I	430_Q	0.694	0.43
424_D	695_S	0.692	0.43
394_V	450_V	0.689	0.43
535_A	556_R	0.689	0.43
108_T	305_P	0.688	0.43
174_F	724_P	0.687	0.43
545_Q	548_R	0.686	0.42
534_V	600_A	0.686	0.42
114_A	118_T	0.686	0.42
431_W	435_L	0.685	0.42
45_G	483_C	0.684	0.42
457_Y	700_H	0.684	0.42
28_Q	177_Q	0.684	0.42
367_S	709_A	0.683	0.42
294_L	624_A	0.683	0.42
519_R	687_R	0.680	0.42
684_A	687_R	0.680	0.42
394_V	408_V	0.680	0.42
248_K	277_L	0.680	0.42
677_A	708_L	0.680	0.42
517_C	528_L	0.680	0.42
564_Y	567_T	0.679	0.42
8_G	50_L	0.679	0.42
484_L	522_Y	0.676	0.42
705_R	719_F	0.674	0.41
332_I	358_R	0.673	0.41
626_A	666_W	0.673	0.41
190_W	205_A	0.672	0.41
93_S	147_D	0.671	0.41
115_E	123_R	0.669	0.41
650_F	671_A	0.669	0.41
527_H	530_G	0.669	0.41
501_L	699_I	0.668	0.41
497_I	689_I	0.668	0.41
512_L	540_D	0.667	0.41
330_P	504_I	0.665	0.41
435_L	459_S	0.665	0.41
207_I	211_K	0.665	0.41
692_L	715_F	0.665	0.41
515_G	623_E	0.665	0.41
293_D	621_A	0.663	0.40
665_A	673_A	0.663	0.40
115_E	127_P	0.663	0.40
116_M	127_P	0.663	0.40
345_A	350_I	0.663	0.40
578_L	582_I	0.662	0.40
608_A	612_L	0.662	0.40
168_D	710_H	0.661	0.40
123_R	179_V	0.660	0.40
247_A	621_A	0.660	0.40
221_I	487_H	0.658	0.40
183_E	352_N	0.658	0.40
605_L	626_A	0.658	0.40
103_V	144_M	0.657	0.40
68_L	132_T	0.657	0.40
294_L	621_A	0.657	0.40
128_F	305_P	0.656	0.40
207_I	310_L	0.655	0.40
139_T	363_V	0.655	0.40
146_Y	153_M	0.653	0.40
435_L	439_Q	0.652	0.39
90_I	177_Q	0.652	0.39
12_R	106_A	0.650	0.39
709_A	717_L	0.649	0.39
489_W	691_T	0.649	0.39
178_P	225_H	0.649	0.39
480_A	483_C	0.648	0.39
144_M	434_A	0.647	0.39
266_Q	399_A	0.647	0.39
51_R	81_W	0.647	0.39
68_L	133_H	0.644	0.39
356_V	680_M	0.644	0.39
358_R	589_P	0.644	0.39
557_F	651_W	0.643	0.39
374_S	720_P	0.642	0.39
519_R	526_E	0.641	0.38
612_L	617_E	0.639	0.38
670_D	703_L	0.637	0.38
243_K	421_D	0.637	0.38
351_H	546_P	0.636	0.38
598_F	704_L	0.635	0.38
439_Q	445_T	0.635	0.38
417_Q	438_M	0.634	0.38
396_C	735_G	0.634	0.38
302_P	536_L	0.634	0.38
481_A	525_C	0.634	0.38
26_V	678_A	0.633	0.38
228_C	235_A	0.631	0.38
115_E	118_T	0.631	0.38
547_W	574_N	0.631	0.38
16_K	380_D	0.630	0.37
581_A	584_R	0.629	0.37
554_C	604_A	0.629	0.37
25_F	360_D	0.628	0.37
677_A	684_A	0.628	0.37
18_Q	23_R	0.628	0.37
86_T	731_S	0.628	0.37
25_F	62_Y	0.626	0.37
190_W	197_A	0.626	0.37
253_M	303_A	0.626	0.37
484_L	575_W	0.626	0.37
429_M	432_R	0.625	0.37
106_A	133_H	0.624	0.37
16_K	133_H	0.623	0.37
108_T	586_I	0.623	0.37
428_Q	432_R	0.623	0.37
243_K	598_F	0.623	0.37
330_P	374_S	0.622	0.37
272_A	378_V	0.622	0.37
10_Q	79_F	0.621	0.37
221_I	303_A	0.621	0.37
187_H	199_Q	0.621	0.37
373_R	405_F	0.621	0.37
328_K	424_D	0.620	0.37
143_A	356_V	0.620	0.37
684_A	689_I	0.620	0.37
555_L	583_E	0.619	0.37
515_G	593_S	0.619	0.37
130_N	695_S	0.619	0.37
401_L	540_D	0.619	0.37
531_L	597_F	0.619	0.37
72_D	413_A	0.618	0.36
338_L	654_W	0.618	0.36
551_L	575_W	0.614	0.36
291_A	297_V	0.613	0.36
264_A	278_V	0.613	0.36
593_S	623_E	0.612	0.36
545_Q	581_A	0.612	0.36
280_K	288_D	0.612	0.36
439_Q	466_M	0.612	0.36
325_L	340_D	0.611	0.36
652_Q	655_L	0.611	0.36
155_A	158_L	0.610	0.36
517_C	645_L	0.610	0.36
381_A	414_V	0.609	0.36
396_C	406_C	0.608	0.36
406_C	732_L	0.608	0.36
17_V	20_V	0.608	0.36
320_M	424_D	0.608	0.36
202_A	206_A	0.606	0.35
18_Q	21_G	0.606	0.35
236_V	290_I	0.606	0.35
45_G	693_V	0.606	0.35
300_M	320_M	0.606	0.35
69_A	119_P	0.605	0.35
467_N	470_T	0.604	0.35
627_A	634_H	0.604	0.35
422_L	581_A	0.604	0.35
437_L	442_Y	0.603	0.35
500_T	695_S	0.602	0.35
580_R	583_E	0.601	0.35
650_F	653_Q	0.600	0.35
177_Q	403_N	0.600	0.35
203_L	255_P	0.599	0.35
460_S	591_A	0.598	0.35
192_S	201_A	0.598	0.35
415_L	732_L	0.597	0.35
21_G	24_P	0.597	0.35
82_S	85_P	0.595	0.35
638_M	682_E	0.594	0.34
497_I	617_E	0.594	0.34
206_A	349_L	0.594	0.34
430_Q	486_E	0.594	0.34
293_D	602_A	0.594	0.34
359_M	374_S	0.593	0.34
474_L	509_N	0.593	0.34
53_D	124_Y	0.593	0.34
581_A	586_I	0.593	0.34
90_I	225_H	0.593	0.34
328_K	418_H	0.592	0.34
157_P	163_D	0.592	0.34
575_W	579_A	0.592	0.34
381_A	669_H	0.591	0.34
528_L	687_R	0.589	0.34
43_G	96_G	0.588	0.34
141_I	709_A	0.588	0.34
129_I	182_P	0.587	0.34
243_K	326_S	0.586	0.34
417_Q	442_Y	0.586	0.34
128_F	351_H	0.586	0.34
211_K	316_C	0.586	0.34
399_A	459_S	0.585	0.34
186_P	538_G	0.585	0.34
141_I	146_Y	0.585	0.34
268_L	278_V	0.584	0.34
167_R	179_V	0.584	0.34
600_A	647_L	0.584	0.34
20_V	69_A	0.584	0.34
16_K	250_L	0.584	0.34
50_L	65_C	0.584	0.34
337_A	344_I	0.583	0.34
292_P	351_H	0.583	0.34
484_L	691_T	0.583	0.34
484_L	520_V	0.583	0.34
214_K	346_D	0.583	0.34
129_I	370_M	0.582	0.33
674_Q	678_A	0.582	0.33
616_G	700_H	0.581	0.33
299_V	327_G	0.580	0.33
545_Q	574_N	0.579	0.33
647_L	672_L	0.579	0.33
227_A	424_D	0.578	0.33
402_K	598_F	0.578	0.33
430_Q	434_A	0.578	0.33
311_L	378_V	0.578	0.33
265_R	636_V	0.578	0.33
496_V	520_V	0.577	0.33
110_P	114_A	0.577	0.33
601_V	651_W	0.575	0.33
174_F	589_P	0.575	0.33
13_I	97_T	0.575	0.33
13_I	448_Y	0.574	0.33
651_W	655_L	0.574	0.33
497_I	684_A	0.574	0.33
33_L	57_F	0.574	0.33
268_L	301_L	0.573	0.33
103_V	613_S	0.573	0.33
370_M	723_L	0.573	0.33
327_G	531_L	0.573	0.33
500_T	693_V	0.573	0.33
129_I	330_P	0.572	0.33
515_G	592_S	0.572	0.33
518_L	692_L	0.571	0.33
154_A	723_L	0.571	0.33
58_L	62_Y	0.571	0.33
422_L	598_F	0.571	0.33
694_F	705_R	0.571	0.33
177_Q	180_A	0.570	0.32
396_C	730_L	0.570	0.32
309_L	418_H	0.570	0.32
100_T	106_A	0.570	0.32
378_V	416_S	0.569	0.32
243_K	277_L	0.569	0.32
484_L	518_L	0.569	0.32
481_A	518_L	0.569	0.32
634_H	671_A	0.568	0.32
553_Q	597_F	0.568	0.32
455_P	506_M	0.567	0.32
98_M	143_A	0.567	0.32
501_L	534_V	0.566	0.32
187_H	202_A	0.566	0.32
423_S	456_G	0.566	0.32
89_T	238_T	0.565	0.32
304_N	725_A	0.564	0.32
400_D	540_D	0.564	0.32
529_G	638_M	0.563	0.32
273_A	549_N	0.563	0.32
202_A	673_A	0.563	0.32
77_E	725_A	0.563	0.32
667_A	670_D	0.563	0.32
517_C	680_M	0.562	0.32
67_P	133_H	0.562	0.32
108_T	311_L	0.562	0.32
320_M	737_I	0.562	0.32
449_V	468_L	0.561	0.32
13_I	288_D	0.561	0.32
473_V	477_H	0.561	0.32
38_D	50_L	0.560	0.32
33_L	432_R	0.560	0.32
451_H	464_R	0.560	0.32
406_C	617_E	0.560	0.32
541_L	548_R	0.560	0.32
28_Q	133_H	0.559	0.32
55_E	685_T	0.559	0.32
564_Y	575_W	0.559	0.32
121_E	271_P	0.559	0.32
102_I	347_G	0.559	0.32
651_W	654_W	0.559	0.32
165_E	171_D	0.558	0.32
117_N	470_T	0.558	0.32
666_W	703_L	0.558	0.32
228_C	311_L	0.557	0.31
42_D	291_A	0.557	0.31
629_C	663_Q	0.556	0.31
236_V	288_D	0.556	0.31
330_P	430_Q	0.556	0.31
190_W	206_A	0.555	0.31
281_K	577_V	0.554	0.31
8_G	27_W	0.554	0.31
326_S	402_K	0.554	0.31
294_L	700_H	0.554	0.31
28_Q	68_L	0.554	0.31
489_W	494_G	0.554	0.31
457_Y	577_V	0.554	0.31
267_L	369_E	0.553	0.31
319_V	589_P	0.553	0.31
125_R	204_Q	0.552	0.31
450_V	477_H	0.552	0.31
497_I	687_R	0.551	0.31
244_H	325_L	0.551	0.31
158_L	344_I	0.551	0.31
625_L	628_S	0.551	0.31
130_N	146_Y	0.550	0.31
396_C	450_V	0.550	0.31
625_L	662_N	0.549	0.31
501_L	694_F	0.549	0.31
403_N	545_Q	0.548	0.31
174_F	553_Q	0.548	0.31
286_L	680_M	0.548	0.31
582_I	740_A	0.548	0.31
281_K	319_V	0.547	0.31
499_L	559_P	0.547	0.31
474_L	525_C	0.547	0.31
499_L	708_L	0.546	0.31
400_D	456_G	0.546	0.31
571_Q	575_W	0.546	0.31
15_G	18_Q	0.545	0.30
190_W	292_P	0.545	0.30
267_L	378_V	0.545	0.30
576_S	586_I	0.545	0.30
591_A	725_A	0.545	0.30
224_F	477_H	0.545	0.30
374_S	506_M	0.544	0.30
250_L	448_Y	0.544	0.30
33_L	50_L	0.544	0.30
294_L	705_R	0.543	0.30
619_A	669_H	0.543	0.30
152_V	354_D	0.543	0.30
68_L	552_A	0.543	0.30
689_I	715_F	0.543	0.30
45_G	68_L	0.543	0.30
547_W	551_L	0.542	0.30
278_V	366_E	0.542	0.30
483_C	737_I	0.542	0.30
179_V	499_L	0.542	0.30
613_S	617_E	0.540	0.30
311_L	323_G	0.540	0.30
708_L	712_L	0.539	0.30
43_G	133_H	0.539	0.30
15_G	19_G	0.539	0.30
311_L	318_L	0.539	0.30
207_I	316_C	0.538	0.30
8_G	52_E	0.538	0.30
415_L	565_S	0.538	0.30
605_L	634_H	0.538	0.30
520_V	695_S	0.537	0.30
16_K	286_L	0.537	0.30
152_V	431_W	0.537	0.30
121_E	171_D	0.537	0.30
218_I	320_M	0.537	0.30
419_L	430_Q	0.536	0.30
450_V	737_I	0.536	0.30
417_Q	434_A	0.536	0.30
211_K	315_Q	0.536	0.30
570_V	574_N	0.536	0.30
640_R	686_M	0.536	0.30
645_L	679_L	0.535	0.30
163_D	194_G	0.535	0.30
178_P	498_A	0.535	0.30
130_N	402_K	0.535	0.30
29_L	32_Q	0.535	0.30
102_I	735_G	0.534	0.30
50_L	57_F	0.534	0.30
511_A	590_L	0.533	0.30
707_R	710_H	0.532	0.29
290_I	651_W	0.532	0.29
48_V	57_F	0.532	0.29
607_C	661_V	0.531	0.29
45_G	179_V	0.531	0.29
369_E	719_F	0.531	0.29
418_H	430_Q	0.530	0.29
347_G	656_N	0.530	0.29
534_V	647_L	0.529	0.29
647_L	675_G	0.529	0.29
622_L	665_A	0.529	0.29
522_Y	736_V	0.528	0.29
246_P	250_L	0.528	0.29
24_P	41_N	0.528	0.29
432_R	436_R	0.528	0.29
270_T	469_P	0.527	0.29
496_V	593_S	0.527	0.29
103_V	106_A	0.527	0.29
174_F	417_Q	0.527	0.29
381_A	442_Y	0.527	0.29
45_G	133_H	0.527	0.29
442_Y	581_A	0.526	0.29
292_P	546_P	0.526	0.29
581_A	588_A	0.526	0.29
255_P	707_R	0.525	0.29
190_W	195_E	0.525	0.29
504_I	540_D	0.525	0.29
126_Y	589_P	0.525	0.29
550_L	651_W	0.525	0.29
155_A	335_E	0.524	0.29
305_P	396_C	0.524	0.29
67_P	292_P	0.524	0.29
563_N	567_T	0.524	0.29
535_A	549_N	0.523	0.29
623_E	627_A	0.523	0.29
636_V	649_T	0.523	0.29
44_D	221_I	0.523	0.29
93_S	665_A	0.523	0.29
110_P	269_T	0.522	0.29
115_E	281_K	0.522	0.29
26_V	48_V	0.522	0.29
422_L	435_L	0.521	0.29
38_D	79_F	0.520	0.29
102_I	154_A	0.519	0.28
254_L	317_P	0.519	0.28
180_A	345_A	0.519	0.28
177_Q	225_H	0.519	0.28
48_V	323_G	0.519	0.28
130_N	180_A	0.519	0.28
197_A	200_E	0.518	0.28
252_V	564_Y	0.518	0.28
413_A	536_L	0.518	0.28
18_Q	24_P	0.518	0.28
639_P	646_D	0.517	0.28
108_T	225_H	0.517	0.28
659_A	667_A	0.516	0.28
494_G	690_T	0.516	0.28
25_F	377_Y	0.516	0.28
551_L	679_L	0.516	0.28
402_K	668_F	0.516	0.28
130_N	179_V	0.516	0.28
91_R	302_P	0.514	0.28
139_T	381_A	0.514	0.28
188_L	199_Q	0.513	0.28
177_Q	484_L	0.513	0.28
494_G	691_T	0.513	0.28
728_G	738_A	0.513	0.28
350_I	354_D	0.513	0.28
69_A	384_L	0.512	0.28
512_L	543_A	0.512	0.28
484_L	493_G	0.511	0.28
180_A	486_E	0.511	0.28
208_A	713_A	0.511	0.28
295_N	731_S	0.510	0.28
536_L	600_A	0.510	0.28
307_Q	431_W	0.510	0.28
515_G	672_L	0.510	0.28
225_H	359_M	0.510	0.28
130_N	483_C	0.510	0.28
669_H	712_L	0.510	0.28
634_H	640_R	0.509	0.28
699_I	704_L	0.509	0.28
629_C	662_N	0.508	0.28
179_V	378_V	0.508	0.28
273_A	397_L	0.508	0.28
374_S	381_A	0.508	0.28
533_A	591_A	0.507	0.28
54_P	363_V	0.507	0.28
602_A	618_A	0.506	0.28
241_A	265_R	0.506	0.28
220_G	307_Q	0.506	0.28
433_E	464_R	0.506	0.28
115_E	649_T	0.506	0.28
357_Q	434_A	0.505	0.27
381_A	474_L	0.505	0.27
304_N	530_G	0.505	0.27
634_H	654_W	0.505	0.27
20_V	23_R	0.505	0.27
152_V	357_Q	0.505	0.27
307_Q	351_H	0.504	0.27
441_I	607_C	0.504	0.27
246_P	417_Q	0.504	0.27
254_L	363_V	0.504	0.27
246_P	442_Y	0.504	0.27
16_K	101_Q	0.503	0.27
302_P	326_S	0.502	0.27
550_L	557_F	0.502	0.27
179_V	365_R	0.502	0.27
547_W	603_A	0.502	0.27
290_I	678_A	0.502	0.27
17_V	23_R	0.501	0.27
203_L	207_I	0.501	0.27
272_A	377_Y	0.501	0.27
263_A	368_G	0.501	0.27
709_A	719_F	0.501	0.27
13_I	62_Y	0.501	0.27
582_I	619_A	0.500	0.27
532_P	648_A	0.500	0.27
515_G	698_V	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3vthA	1	0.976	100	0.237	Contact Map
4g9iA	1	0.972	100	0.25	Contact Map
3ttcA	1	0.8587	100	0.313	Contact Map
3enoA	1	0.3773	100	0.868	Contact Map
1k7jA	1	0.2573	100	0.871	Contact Map
1jcuA	1	0.2613	100	0.872	Contact Map
2ivnA	1	0.3707	100	0.872	Contact Map
4k25A	2	0.368	100	0.873	Contact Map
2eqaA	1	0.4013	100	0.874	Contact Map
3zeuB	1	0.3787	100	0.88	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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