CYDD - ECOLI - GREMLIN Contacts

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CYDD - ATP-binding/permease protein CydD

UniProt:	P29018	Sequences: MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEELFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGRYAELSVAGGPFATLLAHRQEEI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11405
Length:	588 (560)
Sequences:	53002 (37813)
Seq/√Len:	1597.9

ECOLI - CYDD MSBA MDLB MDLA CYDC YOJI YDDA
BACSU - YHEH YFIC BMRA YGAD YKNV SUNT YWJA YKNU CYDD YFIB YHEI CYDC YVRA OPUAA OPUCA
HALSA - Q9HSQ7 Q9HMX3 Q9HMW0 BTUDA
SULSO - Q97UJ9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
465_S	475_V	4.465	1.00
351_E	372_T	4.429	1.00
374_P	377_Q	4.275	1.00
377_Q	552_V	4.222	1.00
354_E	368_P	4.212	1.00
552_V	564_Q	4.080	1.00
437_A	441_D	4.003	1.00
460_D	465_S	3.886	1.00
440_R	452_E	3.871	1.00
353_E	405_S	3.869	1.00
567_Y	577_F	3.769	1.00
349_T	372_T	3.557	1.00
353_E	407_R	3.536	1.00
465_S	469_P	3.493	1.00
405_S	412_E	3.305	1.00
367_G	560_R	3.108	1.00
440_R	476_D	3.086	1.00
574_G	578_A	3.004	1.00
440_R	444_L	3.002	1.00
452_E	456_Q	2.958	1.00
364_T	367_G	2.944	1.00
451_S	454_E	2.923	1.00
352_A	355_L	2.914	1.00
356_F	368_P	2.769	1.00
459_L	475_V	2.722	1.00
424_H	505_S	2.685	1.00
393_L	540_V	2.684	1.00
393_L	508_L	2.648	1.00
351_E	407_R	2.594	1.00
457_A	461_N	2.560	1.00
349_T	374_P	2.466	1.00
358_T	364_T	2.443	1.00
554_W	564_Q	2.415	1.00
566_R	569_E	2.402	1.00
456_Q	465_S	2.390	1.00
563_E	573_A	2.390	1.00
503_P	535_Q	2.344	1.00
417_S	420_S	2.343	1.00
373_L	379_A	2.340	1.00
473_Q	477_T	2.334	1.00
356_F	403_Q	2.321	1.00
443_V	459_L	2.319	1.00
356_F	364_T	2.316	1.00
398_G	401_S	2.302	1.00
156_V	160_P	2.301	1.00
440_R	455_L	2.264	1.00
563_E	574_G	2.239	1.00
447_R	454_E	2.224	1.00
563_E	575_G	2.219	1.00
426_S	504_C	2.216	1.00
378_R	550_W	2.138	1.00
557_Q	576_P	2.120	1.00
349_T	375_A	2.117	1.00
456_Q	460_D	2.091	1.00
371_F	554_W	2.084	1.00
529_N	549_D	2.044	1.00
50_Q	284_G	2.014	1.00
464_V	467_F	2.006	1.00
443_V	455_L	1.987	1.00
454_E	503_P	1.976	1.00
521_E	543_Q	1.972	1.00
401_S	414_R	1.961	1.00
352_A	371_F	1.957	1.00
358_T	402_Y	1.955	1.00
373_L	538_L	1.934	1.00
565_G	569_E	1.926	1.00
456_Q	469_P	1.926	1.00
325_K	329_E	1.921	1.00
354_E	370_N	1.906	1.00
20_S	97_A	1.894	1.00
18_V	21_Q	1.892	1.00
63_L	67_T	1.881	1.00
105_R	332_L	1.870	1.00
197_A	234_D	1.864	1.00
348_V	409_N	1.841	1.00
16_Q	101_Q	1.836	1.00
522_Q	526_E	1.801	1.00
458_A	462_A	1.784	1.00
379_A	552_V	1.768	1.00
162_N	271_S	1.744	1.00
50_Q	282_D	1.741	1.00
379_A	554_W	1.739	1.00
444_L	455_L	1.737	1.00
392_L	556_M	1.732	1.00
562_I	576_P	1.732	1.00
457_A	460_D	1.727	1.00
463_W	523_R	1.726	1.00
452_E	476_D	1.719	1.00
557_Q	562_I	1.710	1.00
554_W	561_I	1.692	1.00
444_L	452_E	1.682	1.00
220_R	223_A	1.682	1.00
380_V	550_W	1.680	1.00
377_Q	551_D	1.669	1.00
378_R	539_M	1.666	1.00
461_N	530_A	1.652	1.00
516_L	524_V	1.615	1.00
480_G	485_R	1.610	1.00
350_I	538_L	1.609	1.00
571_S	581_L	1.595	1.00
450_A	501_L	1.590	1.00
347_P	409_N	1.588	1.00
412_E	415_D	1.577	1.00
67_T	71_L	1.577	1.00
443_V	501_L	1.567	1.00
381_L	554_W	1.566	1.00
129_Q	323_S	1.554	1.00
349_T	409_N	1.546	1.00
454_E	457_A	1.541	1.00
479_V	486_L	1.539	1.00
108_Q	332_L	1.528	1.00
466_E	469_P	1.520	1.00
459_L	468_L	1.514	1.00
192_R	322_D	1.484	1.00
456_Q	475_V	1.481	1.00
64_L	68_L	1.474	1.00
266_V	270_F	1.470	1.00
381_L	392_L	1.455	1.00
548_A	568_A	1.455	1.00
563_E	578_A	1.448	1.00
159_F	166_A	1.448	1.00
473_Q	478_P	1.448	1.00
200_R	234_D	1.443	1.00
374_P	552_V	1.440	1.00
384_R	557_Q	1.438	1.00
576_P	579_T	1.437	1.00
204_H	231_A	1.432	1.00
453_Q	456_Q	1.428	1.00
366_A	369_L	1.419	1.00
397_S	427_W	1.410	1.00
541_T	546_D	1.406	1.00
46_A	292_L	1.404	1.00
105_R	109_A	1.399	1.00
352_A	396_L	1.392	1.00
357_I	391_S	1.377	1.00
270_F	278_F	1.375	1.00
193_R	238_R	1.366	1.00
459_L	465_S	1.363	1.00
568_A	572_V	1.361	1.00
395_A	406_L	1.357	1.00
159_F	163_W	1.350	1.00
467_F	490_Q	1.347	1.00
526_E	530_A	1.339	1.00
530_A	533_L	1.339	1.00
436_A	478_P	1.338	1.00
357_I	395_A	1.334	1.00
452_E	455_L	1.324	1.00
368_P	560_R	1.309	1.00
346_D	409_N	1.309	1.00
454_E	501_L	1.308	1.00
19_I	97_A	1.305	1.00
197_A	238_R	1.302	1.00
197_A	200_R	1.301	1.00
186_G	189_D	1.292	1.00
444_L	450_A	1.280	1.00
348_V	375_A	1.276	1.00
426_S	499_A	1.275	1.00
357_I	400_L	1.270	1.00
356_F	367_G	1.268	1.00
453_Q	457_A	1.263	1.00
380_V	547_L	1.255	1.00
42_A	296_L	1.250	1.00
224_E	445_L	1.249	1.00
60_E	64_L	1.249	1.00
411_I	415_D	1.247	1.00
471_L	477_T	1.247	1.00
384_R	576_P	1.241	1.00
532_S	537_T	1.237	1.00
569_E	573_A	1.231	1.00
30_L	79_V	1.230	1.00
353_E	370_N	1.221	1.00
396_L	538_L	1.220	1.00
178_L	182_L	1.216	1.00
385_S	520_S	1.210	1.00
208_R	224_E	1.209	1.00
461_N	500_L	1.208	1.00
480_G	483_A	1.205	1.00
226_E	230_S	1.203	1.00
100_R	104_D	1.200	1.00
349_T	410_G	1.199	1.00
336_Q	417_S	1.196	1.00
105_R	328_M	1.191	1.00
375_A	505_S	1.190	1.00
470_L	490_Q	1.186	1.00
467_F	471_L	1.186	1.00
39_I	153_L	1.184	1.00
271_S	280_H	1.175	1.00
379_A	538_L	1.171	1.00
233_E	237_Q	1.171	1.00
447_R	450_A	1.167	1.00
371_F	392_L	1.163	1.00
439_L	494_V	1.158	1.00
216_R	221_G	1.155	1.00
459_L	464_V	1.155	1.00
369_L	392_L	1.154	1.00
222_E	226_E	1.154	1.00
469_P	474_G	1.151	1.00
464_V	468_L	1.149	1.00
418_P	422_R	1.145	1.00
553_I	567_Y	1.144	1.00
347_P	375_A	1.140	1.00
165_A	293_A	1.140	1.00
117_K	121_S	1.133	1.00
456_Q	459_L	1.131	1.00
211_G	433_Q	1.130	1.00
236_R	240_M	1.129	1.00
364_T	402_Y	1.123	1.00
492_Q	514_A	1.123	1.00
486_L	494_V	1.123	1.00
115_Q	400_L	1.119	1.00
451_S	501_L	1.119	1.00
104_D	108_Q	1.115	1.00
463_W	520_S	1.110	1.00
46_A	50_Q	1.110	1.00
200_R	231_A	1.106	1.00
105_R	108_Q	1.105	1.00
282_D	285_V	1.102	1.00
352_A	406_L	1.100	1.00
411_I	416_L	1.099	1.00
458_A	500_L	1.096	1.00
373_L	536_T	1.094	1.00
43_W	47_R	1.092	1.00
378_R	537_T	1.091	1.00
172_T	260_S	1.089	1.00
466_E	470_L	1.088	1.00
224_E	227_S	1.086	1.00
567_Y	571_S	1.086	1.00
190_A	241_E	1.085	1.00
102_V	327_F	1.080	1.00
158_I	293_A	1.080	1.00
354_E	403_Q	1.072	1.00
555_V	576_P	1.068	1.00
118_P	121_S	1.068	1.00
23_W	89_H	1.068	1.00
321_A	325_K	1.067	1.00
97_A	101_Q	1.067	1.00
420_S	423_K	1.067	1.00
33_V	79_V	1.066	1.00
267_Y	271_S	1.064	1.00
89_H	93_H	1.062	1.00
350_I	396_L	1.059	1.00
539_M	550_W	1.057	1.00
462_A	497_A	1.055	1.00
121_S	199_A	1.054	1.00
352_A	392_L	1.047	1.00
359_S	365_L	1.045	1.00
408_I	421_W	1.042	1.00
14_K	18_V	1.036	1.00
463_W	526_E	1.035	1.00
337_R	415_D	1.032	1.00
428_V	499_A	1.032	1.00
432_P	495_A	1.030	1.00
230_S	234_D	1.028	1.00
541_T	547_L	1.027	1.00
463_W	527_A	1.025	1.00
115_Q	394_N	1.025	1.00
47_R	51_H	1.018	1.00
204_H	227_S	1.015	1.00
44_F	65_P	1.011	1.00
364_T	403_Q	1.007	1.00
241_E	244_R	1.003	1.00
463_W	530_A	0.999	1.00
505_S	535_Q	0.994	1.00
499_A	507_L	0.994	1.00
182_L	186_G	0.993	1.00
27_S	87_G	0.993	1.00
152_L	156_V	0.990	1.00
455_L	475_V	0.989	1.00
223_A	227_S	0.988	1.00
167_L	171_G	0.987	1.00
25_N	29_L	0.986	1.00
441_D	444_L	0.985	1.00
30_L	82_L	0.985	1.00
164_A	280_H	0.980	1.00
523_R	526_E	0.978	1.00
22_R	26_I	0.977	1.00
228_I	232_S	0.975	1.00
21_Q	25_N	0.973	1.00
507_L	535_Q	0.973	1.00
511_E	542_H	0.971	1.00
458_A	501_L	0.967	1.00
220_R	224_E	0.965	1.00
215_L	224_E	0.965	1.00
193_R	197_A	0.964	1.00
457_A	503_P	0.964	1.00
132_D	320_A	0.963	1.00
355_L	395_A	0.963	1.00
46_A	285_V	0.960	1.00
192_R	196_L	0.959	1.00
405_S	414_R	0.954	1.00
519_H	523_R	0.952	1.00
113_W	117_K	0.950	1.00
398_G	418_P	0.949	1.00
351_E	410_G	0.949	1.00
163_W	167_L	0.949	1.00
227_S	231_A	0.948	1.00
368_P	403_Q	0.943	1.00
387_S	556_M	0.940	1.00
377_Q	564_Q	0.939	1.00
96_F	100_R	0.938	1.00
380_V	541_T	0.937	1.00
318_V	322_D	0.935	1.00
473_Q	476_D	0.935	1.00
461_N	531_A	0.934	1.00
468_L	475_V	0.934	1.00
234_D	238_R	0.934	1.00
64_L	67_T	0.933	1.00
385_S	493_R	0.930	1.00
223_A	226_E	0.930	1.00
30_L	86_V	0.928	1.00
337_R	340_A	0.928	1.00
569_E	572_V	0.927	1.00
268_F	290_G	0.924	1.00
353_E	372_T	0.917	1.00
110_G	333_A	0.917	1.00
416_L	421_W	0.916	1.00
420_S	424_H	0.916	1.00
406_L	413_L	0.914	1.00
440_R	456_Q	0.913	1.00
556_M	561_I	0.913	1.00
390_S	394_N	0.909	1.00
455_L	501_L	0.908	1.00
164_A	271_S	0.906	1.00
351_E	370_N	0.905	1.00
460_D	469_P	0.903	1.00
378_R	529_N	0.903	1.00
229_R	233_E	0.901	1.00
450_A	454_E	0.900	1.00
233_E	236_R	0.896	1.00
358_T	365_L	0.896	1.00
428_V	496_V	0.893	1.00
225_I	229_R	0.892	1.00
20_S	93_H	0.890	1.00
419_E	423_K	0.890	1.00
334_H	401_S	0.889	1.00
179_F	252_I	0.888	1.00
160_P	163_W	0.888	1.00
479_V	485_R	0.885	1.00
378_R	532_S	0.884	1.00
397_S	425_L	0.882	1.00
543_Q	546_D	0.880	1.00
240_M	244_R	0.878	1.00
231_A	234_D	0.877	1.00
397_S	508_L	0.876	1.00
440_R	475_V	0.875	1.00
71_L	75_L	0.873	1.00
488_V	493_R	0.871	1.00
125_L	326_T	0.871	1.00
561_I	564_Q	0.870	1.00
102_V	126_V	0.868	1.00
101_Q	105_R	0.868	1.00
112_A	333_A	0.868	1.00
186_G	245_L	0.868	1.00
408_I	506_L	0.867	1.00
227_S	230_S	0.865	1.00
464_V	470_L	0.863	1.00
155_V	166_A	0.862	1.00
190_A	238_R	0.857	1.00
193_R	241_E	0.856	1.00
435_P	442_N	0.853	1.00
461_N	465_S	0.852	1.00
380_V	553_I	0.851	1.00
194_N	239_T	0.850	1.00
189_D	193_R	0.848	1.00
358_T	362_G	0.847	1.00
513_A	524_V	0.846	1.00
112_A	116_G	0.843	1.00
345_T	409_N	0.843	1.00
27_S	90_A	0.842	1.00
186_G	190_A	0.842	1.00
272_Y	281_Y	0.841	1.00
181_A	185_M	0.841	1.00
375_A	409_N	0.841	1.00
226_E	229_R	0.841	1.00
469_P	475_V	0.840	1.00
129_Q	320_A	0.839	1.00
109_A	330_T	0.836	1.00
43_W	157_A	0.834	1.00
575_G	578_A	0.834	1.00
213_E	394_N	0.831	1.00
47_R	65_P	0.829	1.00
177_P	181_A	0.829	1.00
576_P	580_L	0.827	1.00
343_A	416_L	0.826	1.00
158_I	166_A	0.826	1.00
238_R	241_E	0.826	1.00
573_A	578_A	0.825	1.00
479_V	483_A	0.824	1.00
61_A	64_L	0.823	1.00
341_E	411_I	0.821	1.00
168_I	267_Y	0.820	1.00
37_L	75_L	0.820	1.00
557_Q	560_R	0.820	1.00
507_L	532_S	0.818	1.00
413_L	421_W	0.818	1.00
480_G	484_A	0.818	1.00
496_V	509_L	0.817	1.00
157_A	161_S	0.816	1.00
434_L	494_V	0.815	1.00
407_R	410_G	0.813	1.00
37_L	79_V	0.809	1.00
15_Q	18_V	0.805	1.00
434_L	491_A	0.804	1.00
350_I	408_I	0.804	1.00
464_V	494_V	0.803	1.00
331_P	335_P	0.803	1.00
222_E	225_I	0.802	1.00
467_F	470_L	0.800	1.00
438_T	441_D	0.799	1.00
504_C	535_Q	0.797	1.00
574_G	579_T	0.797	1.00
369_L	561_I	0.795	1.00
356_F	402_Y	0.795	1.00
443_V	475_V	0.789	1.00
269_G	273_L	0.788	1.00
423_K	502_N	0.788	1.00
193_R	196_L	0.786	1.00
345_T	505_S	0.785	1.00
201_L	235_F	0.784	1.00
211_G	214_T	0.783	1.00
214_T	218_F	0.783	1.00
157_A	160_P	0.782	1.00
212_M	216_R	0.781	1.00
255_F	259_L	0.780	1.00
360_P	363_K	0.780	1.00
37_L	72_T	0.779	1.00
23_W	93_H	0.778	1.00
425_L	506_L	0.778	1.00
462_A	493_R	0.777	1.00
443_V	494_V	0.777	1.00
358_T	361_E	0.775	1.00
47_R	50_Q	0.775	1.00
44_F	72_T	0.774	1.00
14_K	17_S	0.772	1.00
492_Q	515_S	0.770	1.00
521_E	525_M	0.770	1.00
43_W	46_A	0.769	1.00
161_S	285_V	0.769	1.00
153_L	156_V	0.769	1.00
343_A	346_D	0.768	1.00
571_S	578_A	0.768	1.00
23_W	86_V	0.766	1.00
493_R	520_S	0.766	1.00
147_A	306_D	0.765	1.00
44_F	68_L	0.764	1.00
121_S	125_L	0.763	1.00
341_E	415_D	0.762	1.00
339_E	343_A	0.762	1.00
51_H	61_A	0.761	1.00
416_L	420_S	0.760	1.00
237_Q	241_E	0.760	1.00
78_W	82_L	0.757	1.00
31_G	146_L	0.756	1.00
444_L	449_D	0.756	1.00
171_G	174_P	0.755	1.00
132_D	316_Q	0.755	1.00
15_Q	101_Q	0.754	1.00
159_F	170_L	0.752	1.00
234_D	237_Q	0.750	1.00
431_N	491_A	0.750	1.00
471_L	486_L	0.748	1.00
164_A	167_L	0.748	1.00
65_P	68_L	0.747	1.00
348_V	536_T	0.746	1.00
267_Y	270_F	0.746	1.00
50_Q	53_I	0.746	1.00
67_T	70_V	0.745	1.00
382_V	555_V	0.744	1.00
36_I	40_A	0.744	1.00
105_R	331_P	0.743	1.00
525_M	546_D	0.739	1.00
110_G	334_H	0.738	1.00
507_L	537_T	0.738	1.00
102_V	324_L	0.736	1.00
358_T	363_K	0.736	1.00
447_R	503_P	0.735	1.00
573_A	576_P	0.735	1.00
197_A	231_A	0.734	1.00
343_A	420_S	0.733	1.00
272_Y	290_G	0.733	1.00
136_Y	317_A	0.733	1.00
20_S	23_W	0.733	1.00
447_R	502_N	0.732	1.00
81_W	85_R	0.731	1.00
101_Q	104_D	0.730	1.00
324_L	328_M	0.730	1.00
273_L	278_F	0.729	1.00
35_G	149_S	0.727	1.00
106_L	114_I	0.727	1.00
68_L	71_L	0.726	1.00
367_G	558_D	0.725	1.00
444_L	447_R	0.723	1.00
350_I	506_L	0.723	1.00
407_R	412_E	0.723	1.00
66_F	70_V	0.722	1.00
51_H	54_M	0.721	1.00
148_V	152_L	0.719	1.00
162_N	166_A	0.719	1.00
577_F	580_L	0.719	1.00
463_W	466_E	0.718	1.00
421_W	425_L	0.716	1.00
322_D	326_T	0.716	1.00
156_V	159_F	0.714	1.00
235_F	239_T	0.714	1.00
161_S	292_L	0.712	1.00
122_W	327_F	0.710	1.00
178_L	181_A	0.709	1.00
154_I	300_F	0.708	1.00
154_I	299_E	0.707	1.00
444_L	448_P	0.706	1.00
378_R	549_D	0.704	1.00
49_L	291_F	0.704	1.00
461_N	527_A	0.702	1.00
26_I	86_V	0.701	1.00
376_G	536_T	0.698	1.00
525_M	541_T	0.698	1.00
567_Y	581_L	0.696	1.00
439_L	468_L	0.696	1.00
552_V	566_R	0.695	1.00
336_Q	418_P	0.695	1.00
118_P	203_G	0.694	1.00
342_L	420_S	0.694	1.00
385_S	511_E	0.694	1.00
185_M	189_D	0.693	1.00
379_A	564_Q	0.693	1.00
63_L	66_F	0.693	1.00
488_V	515_S	0.691	1.00
376_G	534_R	0.691	1.00
241_E	245_L	0.690	1.00
95_R	134_H	0.690	1.00
75_L	79_V	0.689	1.00
359_S	391_S	0.687	1.00
101_Q	328_M	0.687	1.00
472_P	477_T	0.683	1.00
269_G	272_Y	0.683	1.00
342_L	417_S	0.683	1.00
104_D	225_I	0.682	1.00
190_A	193_R	0.682	1.00
363_K	367_G	0.681	1.00
394_N	400_L	0.679	1.00
29_L	33_V	0.678	1.00
34_S	80_V	0.677	1.00
521_E	546_D	0.677	1.00
458_A	497_A	0.677	1.00
552_V	569_E	0.676	1.00
271_S	278_F	0.676	1.00
162_N	165_A	0.675	1.00
336_Q	339_E	0.674	1.00
136_Y	314_K	0.674	1.00
165_A	271_S	0.674	1.00
166_A	293_A	0.674	1.00
436_A	480_G	0.673	1.00
125_L	129_Q	0.672	1.00
527_A	530_A	0.671	1.00
395_A	400_L	0.670	1.00
436_A	485_R	0.669	1.00
513_A	521_E	0.668	1.00
437_A	478_P	0.667	1.00
61_A	65_P	0.666	1.00
496_V	524_V	0.665	1.00
496_V	500_L	0.664	1.00
563_E	576_P	0.664	1.00
43_W	161_S	0.663	1.00
33_V	75_L	0.662	1.00
524_V	527_A	0.661	1.00
457_A	531_A	0.660	1.00
93_H	96_F	0.658	1.00
452_E	475_V	0.657	1.00
95_R	99_R	0.657	1.00
393_L	538_L	0.654	1.00
568_A	571_S	0.654	1.00
347_P	536_T	0.652	1.00
408_I	413_L	0.648	1.00
366_A	556_M	0.647	1.00
31_G	83_R	0.647	1.00
346_D	424_H	0.643	1.00
302_Q	306_D	0.642	1.00
109_A	332_L	0.642	1.00
50_Q	54_M	0.641	1.00
334_H	398_G	0.641	1.00
98_I	130_I	0.638	1.00
144_M	148_V	0.637	1.00
563_E	570_L	0.637	1.00
243_L	247_F	0.636	1.00
373_L	377_Q	0.634	1.00
111_P	115_Q	0.634	1.00
547_L	550_W	0.634	1.00
355_L	404_G	0.634	1.00
259_L	263_L	0.634	1.00
177_P	180_M	0.633	1.00
154_I	296_L	0.633	1.00
464_V	475_V	0.632	1.00
268_F	272_Y	0.631	1.00
454_E	458_A	0.629	1.00
563_E	571_S	0.629	1.00
393_L	427_W	0.629	1.00
508_L	538_L	0.629	1.00
195_F	198_L	0.628	1.00
517_D	520_S	0.628	1.00
381_L	538_L	0.628	1.00
361_E	402_Y	0.627	1.00
22_R	25_N	0.626	1.00
182_L	185_M	0.625	1.00
262_A	266_V	0.625	1.00
60_E	63_L	0.624	1.00
506_L	536_T	0.624	1.00
340_A	343_A	0.623	1.00
199_A	323_S	0.623	1.00
247_F	251_G	0.622	1.00
317_A	320_A	0.620	1.00
459_L	462_A	0.619	1.00
487_S	490_Q	0.617	1.00
102_V	328_M	0.615	1.00
237_Q	240_M	0.615	1.00
431_N	482_Q	0.613	1.00
516_L	520_S	0.613	1.00
463_W	524_V	0.612	1.00
363_K	558_D	0.611	1.00
135_D	313_A	0.611	1.00
438_T	476_D	0.611	1.00
320_A	323_S	0.611	1.00
129_Q	195_F	0.610	1.00
124_T	202_S	0.610	1.00
455_L	459_L	0.610	1.00
40_A	72_T	0.609	1.00
281_Y	285_V	0.608	1.00
567_Y	570_L	0.608	1.00
164_A	267_Y	0.606	1.00
160_P	164_A	0.605	1.00
340_A	420_S	0.604	1.00
116_G	360_P	0.604	1.00
456_Q	468_L	0.604	1.00
352_A	369_L	0.604	1.00
341_E	344_S	0.603	1.00
59_R	63_L	0.603	1.00
518_A	521_E	0.603	1.00
493_R	516_L	0.603	1.00
16_Q	19_I	0.600	1.00
564_Q	569_E	0.600	1.00
369_L	556_M	0.599	1.00
39_I	42_A	0.599	1.00
133_M	321_A	0.598	1.00
102_V	130_I	0.597	1.00
371_F	561_I	0.596	1.00
105_R	330_T	0.596	1.00
357_I	365_L	0.596	1.00
562_I	574_G	0.593	1.00
113_W	122_W	0.591	1.00
135_D	139_R	0.591	1.00
462_A	500_L	0.591	1.00
373_L	378_R	0.590	1.00
521_E	545_E	0.590	1.00
131_D	134_H	0.590	1.00
174_P	178_L	0.590	1.00
25_N	28_R	0.589	1.00
362_G	365_L	0.589	1.00
335_P	417_S	0.588	1.00
358_T	403_Q	0.587	1.00
444_L	459_L	0.587	1.00
53_I	56_N	0.586	1.00
426_S	502_N	0.585	1.00
548_A	567_Y	0.584	1.00
428_V	509_L	0.584	1.00
88_Y	92_Q	0.584	1.00
563_E	579_T	0.581	1.00
162_N	281_Y	0.581	1.00
197_A	235_F	0.581	1.00
196_L	200_R	0.580	1.00
193_R	234_D	0.580	1.00
460_D	466_E	0.580	1.00
204_H	224_E	0.579	1.00
124_T	128_E	0.579	1.00
183_V	249_S	0.579	1.00
474_G	477_T	0.579	1.00
92_Q	95_R	0.579	1.00
355_L	406_L	0.578	1.00
268_F	271_S	0.578	1.00
418_P	421_W	0.577	1.00
88_Y	139_R	0.577	1.00
429_G	432_P	0.575	1.00
462_A	496_V	0.574	1.00
191_N	242_V	0.574	1.00
146_L	150_V	0.574	1.00
526_E	529_N	0.573	1.00
110_G	113_W	0.573	1.00
103_L	107_Q	0.573	1.00
526_E	549_D	0.572	1.00
452_E	459_L	0.572	1.00
204_H	208_R	0.571	1.00
151_P	155_V	0.571	1.00
409_N	505_S	0.571	1.00
258_S	262_A	0.571	1.00
374_P	379_A	0.571	1.00
381_L	540_V	0.570	1.00
195_F	319_G	0.570	1.00
74_V	78_W	0.570	1.00
91_G	138_A	0.570	1.00
190_A	242_V	0.569	1.00
143_Q	306_D	0.569	1.00
263_L	267_Y	0.569	1.00
124_T	198_L	0.567	1.00
18_V	22_R	0.567	1.00
553_I	566_R	0.566	1.00
169_L	297_A	0.565	1.00
430_Q	488_V	0.565	1.00
355_L	370_N	0.565	1.00
394_N	427_W	0.564	1.00
34_S	79_V	0.563	1.00
555_V	563_E	0.563	1.00
525_M	539_M	0.563	1.00
442_N	494_V	0.563	1.00
44_F	47_R	0.563	1.00
558_D	562_I	0.561	1.00
459_L	497_A	0.561	1.00
19_I	101_Q	0.560	1.00
214_T	217_I	0.560	1.00
85_R	89_H	0.559	1.00
444_L	501_L	0.559	1.00
119_A	123_A	0.557	1.00
270_F	273_L	0.557	1.00
408_I	416_L	0.555	1.00
369_L	554_W	0.555	1.00
391_S	400_L	0.554	1.00
577_F	581_L	0.554	1.00
447_R	501_L	0.553	1.00
367_G	370_N	0.553	1.00
111_P	399_F	0.553	1.00
292_L	296_L	0.552	1.00
364_T	368_P	0.551	1.00
77_A	81_W	0.550	1.00
356_F	366_A	0.550	1.00
35_G	38_I	0.549	1.00
147_A	151_P	0.549	1.00
336_Q	340_A	0.549	1.00
513_A	516_L	0.548	1.00
509_L	512_P	0.548	1.00
121_S	323_S	0.548	1.00
385_S	541_T	0.548	1.00
230_S	233_E	0.547	1.00
434_L	479_V	0.547	1.00
382_V	547_L	0.547	1.00
20_S	90_A	0.546	1.00
20_S	94_I	0.545	1.00
254_E	305_R	0.544	1.00
120_G	203_G	0.543	1.00
68_L	72_T	0.543	1.00
346_D	375_A	0.542	1.00
293_A	297_A	0.542	1.00
16_Q	20_S	0.542	1.00
96_F	232_S	0.541	1.00
372_T	564_Q	0.541	1.00
417_S	421_W	0.540	1.00
381_L	556_M	0.540	1.00
98_I	133_M	0.540	1.00
43_W	292_L	0.539	1.00
124_T	199_A	0.538	1.00
35_G	39_I	0.537	1.00
215_L	221_G	0.537	1.00
114_I	117_K	0.537	1.00
85_R	88_Y	0.537	1.00
38_I	76_R	0.536	1.00
260_S	263_L	0.536	1.00
206_L	210_R	0.536	1.00
361_E	364_T	0.536	1.00
538_L	554_W	0.534	1.00
107_Q	110_G	0.533	1.00
31_G	35_G	0.533	1.00
439_L	479_V	0.532	1.00
338_G	342_L	0.532	1.00
557_Q	579_T	0.532	1.00
390_S	393_L	0.531	1.00
175_L	178_L	0.531	1.00
465_S	468_L	0.530	1.00
232_S	236_R	0.529	1.00
489_G	517_D	0.529	1.00
82_L	86_V	0.529	1.00
70_V	74_V	0.529	1.00
198_L	202_S	0.529	1.00
130_I	324_L	0.528	1.00
257_T	261_I	0.528	1.00
33_V	37_L	0.528	1.00
179_F	256_F	0.527	1.00
525_M	549_D	0.527	1.00
340_A	417_S	0.526	1.00
527_A	531_A	0.526	1.00
52_M	61_A	0.526	1.00
520_S	523_R	0.525	1.00
232_S	235_F	0.524	1.00
500_L	527_A	0.524	1.00
385_S	516_L	0.524	1.00
200_R	203_G	0.523	1.00
194_N	198_L	0.522	1.00
123_A	127_L	0.522	1.00
500_L	531_A	0.522	1.00
348_V	505_S	0.521	1.00
79_V	82_L	0.521	1.00
460_D	475_V	0.520	1.00
571_S	574_G	0.519	1.00
341_E	345_T	0.519	1.00
284_G	292_L	0.518	1.00
339_E	417_S	0.518	1.00
339_E	415_D	0.518	1.00
346_D	349_T	0.518	1.00
374_P	536_T	0.518	1.00
126_V	130_I	0.518	1.00
194_N	242_V	0.517	1.00
57_I	61_A	0.516	1.00
84_E	88_Y	0.516	1.00
442_N	498_R	0.515	1.00
155_V	159_F	0.514	1.00
391_S	395_A	0.513	1.00
248_L	251_G	0.513	1.00
27_S	86_V	0.513	1.00
265_A	268_F	0.513	1.00
44_F	69_L	0.512	1.00
346_D	408_I	0.511	1.00
447_R	451_S	0.511	1.00
532_S	535_Q	0.511	1.00
512_P	539_M	0.511	1.00
271_S	279_G	0.510	1.00
125_L	323_S	0.510	1.00
17_S	24_L	0.509	1.00
23_W	90_A	0.509	1.00
155_V	158_I	0.508	1.00
443_V	446_A	0.507	1.00
439_L	464_V	0.507	1.00
411_I	420_S	0.506	1.00
334_H	418_P	0.506	1.00
372_T	375_A	0.506	1.00
468_L	471_L	0.506	1.00
518_A	545_E	0.506	1.00
345_T	348_V	0.505	1.00
208_R	215_L	0.505	1.00
142_P	145_A	0.505	1.00
523_R	527_A	0.504	1.00
95_R	130_I	0.504	1.00
531_A	535_Q	0.504	1.00
147_A	150_V	0.502	1.00
139_R	143_Q	0.502	1.00
34_S	38_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9609	100	0.088	Contact Map
4a82A	2	0.9694	100	0.123	Contact Map
4q4hB	1	0.9796	100	0.153	Contact Map
4f4cA	1	0.9626	100	0.157	Contact Map
3b5xA	2	0.9677	100	0.161	Contact Map
3b60A	2	0.9626	100	0.166	Contact Map
4q4hA	1	0.9677	100	0.17	Contact Map
3zdqA	2	0.9524	100	0.173	Contact Map
3wmgA	1	0.9745	100	0.175	Contact Map
4mrsA	2	0.9864	100	0.176	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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