GREMLIN Database
NRDD - Anaerobic ribonucleoside-triphosphate reductase
UniProt: P28903 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11417
Length: 712 (666)
Sequences: 1670 (700)
Seq/√Len: 27.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
432_D523_R7.8781.00
149_D440_K5.5801.00
424_E519_A5.4101.00
443_M539_F5.3421.00
436_V531_W4.3881.00
439_R534_E4.2811.00
435_L524_L4.2801.00
5_V61_I4.0761.00
530_Q534_E3.9891.00
428_W519_A3.9311.00
142_R155_E3.8571.00
646_E669_D3.8061.00
152_Q156_R3.6671.00
315_I355_E3.3861.00
557_D573_Y3.3231.00
370_Q373_K3.1661.00
661_T666_G3.1321.00
515_A519_A3.0001.00
524_L541_L2.9281.00
527_A530_Q2.8781.00
432_D527_A2.8591.00
572_Y701_R2.7961.00
436_V527_A2.7761.00
419_E430_L2.7701.00
420_A426_T2.7611.00
522_E600_L2.7561.00
21_K43_A2.6720.99
439_R535_T2.6670.99
70_M75_K2.6670.99
661_T668_H2.5890.99
65_V81_Y2.5740.99
586_N589_D2.5730.99
443_M535_T2.5650.99
33_V74_Y2.5640.99
504_G512_Q2.5630.99
308_E352_L2.5530.99
430_L434_R2.5330.99
511_E515_A2.4810.99
295_F330_L2.4810.99
150_V440_K2.4610.99
502_F513_L2.4510.99
160_H552_R2.4300.99
148_R152_Q2.4100.99
415_R557_D2.3690.99
147_P444_T2.3650.99
88_R91_E2.3190.98
542_Y603_G2.2840.98
17_S43_A2.2790.98
525_R529_D2.2730.98
516_K520_I2.2660.98
62_Q66_E2.2610.98
439_R539_F2.2560.98
514_R596_P2.2490.98
45_V72_G2.2370.98
535_T539_F2.2370.98
66_E82_I2.2350.98
28_A74_Y2.2310.98
4_H14_P2.2180.98
540_S603_G2.2120.98
501_L516_K2.2080.98
478_E481_K2.1820.98
45_V68_Q2.1780.98
50_M64_A2.1750.98
543_S601_A2.1720.98
59_N62_Q2.1520.97
28_A77_L2.1500.97
393_N397_E2.1420.97
418_L564_V2.1280.97
78_A82_I2.1060.97
236_V306_I2.0980.97
43_A47_S2.0780.97
420_A500_A2.0680.97
564_V567_V2.0630.97
42_V72_G2.0600.97
523_R527_A2.0400.96
142_R164_L2.0170.96
237_T302_E1.9830.96
57_D60_E1.9830.96
184_L204_A1.9820.96
59_N63_T1.9720.96
522_E526_Q1.9570.95
237_T241_N1.9570.95
351_Q622_E1.9500.95
25_L36_A1.9380.95
439_R443_M1.9300.95
351_Q619_K1.9290.95
240_Y244_R1.9260.95
239_S266_E1.9200.95
246_T262_R1.9170.95
431_L435_L1.9120.95
39_C77_L1.9120.95
592_D627_Y1.9090.95
517_G597_Y1.9040.95
4_H12_K1.8980.95
158_D415_R1.8970.95
579_L593_F1.8940.95
439_R531_W1.8840.94
526_Q530_Q1.8740.94
514_R597_Y1.8730.94
415_R573_Y1.8640.94
6_M12_K1.8640.94
450_E477_S1.8400.94
70_M82_I1.8290.93
158_D434_R1.8260.93
33_V77_L1.8110.93
199_K238_A1.7900.93
447_A450_E1.7880.93
28_A33_V1.7780.92
33_V76_Q1.7720.92
264_I308_E1.7700.92
39_C43_A1.7570.92
30_A80_A1.7490.92
12_K55_Q1.7430.92
692_N695_K1.7150.91
87_D90_I1.7110.91
428_W431_L1.7040.91
79_R83_E1.6970.91
68_Q71_S1.6860.90
42_V68_Q1.6830.90
504_G510_N1.6750.90
417_A420_A1.6550.89
550_C695_K1.6480.89
416_I434_R1.6480.89
153_A437_L1.6250.89
423_D426_T1.6230.88
232_L306_I1.5950.88
28_A31_A1.5620.86
6_M55_Q1.5520.86
194_E320_K1.5510.86
552_R556_L1.5470.86
595_A632_V1.5420.86
35_D38_Y1.5420.86
33_V70_M1.5410.86
558_T563_V1.5370.86
393_N396_G1.5330.85
150_V441_A1.5310.85
292_T331_V1.5150.85
200_S266_E1.5050.84
21_K40_A1.5050.84
426_T430_L1.4740.83
419_E561_F1.4720.83
20_I23_A1.4680.83
62_Q92_R1.4680.83
697_E700_K1.4620.82
430_L433_E1.4600.82
691_F699_V1.4590.82
311_L356_C1.4340.81
354_L621_L1.4320.81
31_A77_L1.4260.81
28_A39_C1.4120.80
25_L39_C1.4050.80
49_Q68_Q1.4050.80
62_Q82_I1.4040.80
67_N71_S1.4000.80
28_A34_D1.4000.80
435_L527_A1.3960.79
38_Y74_Y1.3950.79
264_I309_S1.3950.79
43_A65_V1.3950.79
446_I450_E1.3900.79
697_E701_R1.3880.79
589_D592_D1.3880.79
435_L531_W1.3860.79
147_P150_V1.3780.78
492_I550_C1.3750.78
53_R60_E1.3720.78
204_A235_F1.3710.78
88_R92_R1.3690.78
23_A62_Q1.3670.78
67_N75_K1.3650.78
5_V56_V1.3590.78
424_E516_K1.3580.77
308_E312_R1.3550.77
158_D419_E1.3450.77
66_E79_R1.3400.76
13_V16_K1.3400.76
208_T228_I1.3380.76
438_A489_L1.3340.76
62_Q88_R1.3250.76
175_C384_C1.3230.76
66_E88_R1.3170.75
28_A35_D1.3100.75
102_I136_V1.3100.75
698_E702_R1.3090.75
74_Y77_L1.3090.75
58_I62_Q1.3060.75
23_A92_R1.3020.74
519_A526_Q1.2990.74
499_N565_P1.2990.74
514_R518_I1.2930.74
420_A430_L1.2900.74
335_R368_Y1.2890.74
498_I502_F1.2850.73
157_G556_L1.2810.73
17_S44_A1.2810.73
185_T235_F1.2750.73
18_E22_E1.2710.73
8_R92_R1.2680.72
58_I66_E1.2670.72
243_H263_T1.2610.72
15_F47_S1.2510.71
8_R23_A1.2490.71
38_Y48_E1.2450.71
23_A27_A1.2410.71
150_V444_T1.2310.70
28_A75_K1.2290.70
566_G569_D1.2240.70
309_S312_R1.2230.70
67_N74_Y1.2200.69
64_A68_Q1.2200.69
159_I438_A1.2190.69
25_L29_K1.2180.69
525_R602_N1.2120.69
498_I517_G1.2120.69
17_S47_S1.2090.69
47_S51_Q1.2070.69
174_N220_Y1.2060.68
23_A88_R1.2000.68
679_V691_F1.1990.68
629_Y635_Y1.1980.68
62_Q85_R1.1980.68
497_T520_I1.1940.68
86_H90_I1.1920.68
23_A58_I1.1870.67
366_L381_P1.1840.67
25_L28_A1.1820.67
514_R593_F1.1760.66
695_K698_E1.1740.66
421_K426_T1.1720.66
66_E85_R1.1700.66
66_E70_M1.1680.66
417_A497_T1.1650.66
681_G702_R1.1630.66
498_I520_I1.1600.65
314_R330_L1.1590.65
5_V58_I1.1580.65
333_A368_Y1.1570.65
411_L431_L1.1560.65
498_I516_K1.1550.65
510_N513_L1.1520.65
300_S304_R1.1490.65
422_G426_T1.1490.65
502_F516_K1.1440.64
49_Q64_A1.1430.64
628_S635_Y1.1420.64
97_R101_E1.1420.64
432_D435_L1.1410.64
213_A281_L1.1390.64
368_Y378_F1.1350.64
447_A477_S1.1290.63
66_E84_Y1.1260.63
157_G415_R1.1250.63
71_S75_K1.1220.63
5_V561_F1.1190.63
208_T225_I1.1190.63
5_V13_V1.1190.63
62_Q84_Y1.1170.62
156_R560_E1.1160.62
646_E667_N1.1150.62
127_T130_D1.1140.62
315_I352_L1.1120.62
66_E92_R1.1060.62
38_Y73_P1.1030.61
300_S303_S1.1030.61
49_Q53_R1.1020.61
366_L387_F1.0980.61
495_H507_V1.0980.61
590_K607_C1.0960.61
518_I596_P1.0950.61
426_T429_K1.0910.61
8_R62_Q1.0890.60
17_S40_A1.0860.60
42_V64_A1.0840.60
119_N327_F1.0780.60
24_I42_V1.0750.59
176_M219_I1.0720.59
58_I83_E1.0690.59
312_R352_L1.0670.59
582_E701_R1.0640.59
37_D41_T1.0630.58
72_G75_K1.0630.58
427_F497_T1.0600.58
531_W534_E1.0600.58
239_S242_K1.0560.58
416_I430_L1.0560.58
682_Y702_R1.0540.58
298_G303_S1.0500.58
415_R434_R1.0480.57
28_A76_Q1.0460.57
22_E40_A1.0430.57
249_E261_S1.0410.57
334_I367_N1.0400.57
53_R67_N1.0390.57
212_I225_I1.0390.57
307_Q330_L1.0390.57
33_V49_Q1.0360.56
174_N542_Y1.0360.56
21_K42_V1.0340.56
64_A73_P1.0320.56
678_R681_G1.0300.56
70_M78_A1.0300.56
23_A66_E1.0290.56
273_S277_E1.0280.56
42_V70_M1.0260.56
6_M57_D1.0220.55
245_K248_E1.0170.55
43_A46_V1.0160.55
553_F573_Y1.0160.55
27_A92_R1.0130.55
450_E481_K1.0060.54
117_N545_P1.0040.54
443_M447_A1.0030.54
26_R79_R1.0010.54
85_R92_R0.9910.53
23_A85_R0.9900.53
643_E650_T0.9880.53
79_R82_I0.9870.53
135_I138_K0.9860.53
25_L31_A0.9800.52
204_A232_L0.9800.52
660_F675_V0.9780.52
626_D630_Q0.9760.52
682_Y698_E0.9740.52
45_V71_S0.9740.52
50_M56_V0.9710.52
335_R378_F0.9690.51
59_N66_E0.9690.51
293_F310_I0.9680.51
154_H552_R0.9670.51
410_S549_L0.9650.51
227_R231_V0.9640.51
28_A73_P0.9610.51
265_K269_D0.9610.51
508_Y513_L0.9600.51
260_N264_I0.9600.51
84_Y92_R0.9580.51
134_G165_D0.9510.50
451_G475_D0.9510.50
58_I85_R0.9500.50
334_I629_Y0.9470.50
676_T683_L0.9440.50
244_R312_R0.9430.50
435_L523_R0.9380.49
233_A303_S0.9380.49
77_L555_R0.9370.49
175_C385_R0.9360.49
32_E93_E0.9320.49
41_T72_G0.9280.48
534_E539_F0.9270.48
587_P637_T0.9230.48
367_N631_H0.9220.48
268_Y316_A0.9210.48
35_D39_C0.9210.48
25_L67_N0.9180.48
54_N60_E0.9180.48
515_A522_E0.9140.47
71_S74_Y0.9140.47
22_E26_R0.9080.47
154_H157_G0.9080.47
40_A71_S0.9060.47
90_I94_K0.9020.46
22_E25_L0.9010.46
59_N85_R0.9000.46
25_L70_M0.9000.46
492_I546_S0.8980.46
60_E64_A0.8960.46
570_K582_E0.8940.46
58_I92_R0.8930.46
23_A84_Y0.8930.46
197_P238_A0.8930.46
31_A80_A0.8920.46
677_R691_F0.8920.46
352_L355_E0.8880.45
58_I88_R0.8840.45
446_I477_S0.8820.45
411_L438_A0.8790.45
78_A81_Y0.8770.45
127_T131_L0.8770.45
443_M537_Y0.8760.44
428_W523_R0.8750.44
501_L517_G0.8740.44
58_I63_T0.8730.44
644_C662_C0.8730.44
48_E51_Q0.8730.44
368_Y372_V0.8720.44
64_A76_Q0.8720.44
36_A39_C0.8710.44
28_A67_N0.8710.44
13_V80_A0.8710.44
150_V437_L0.8700.44
154_H164_L0.8700.44
553_F557_D0.8680.44
36_A74_Y0.8680.44
103_R140_Y0.8660.44
311_L353_A0.8650.44
512_Q515_A0.8650.44
26_R49_Q0.8640.44
14_P18_E0.8630.44
662_C665_C0.8570.43
216_A223_T0.8560.43
70_M77_L0.8560.43
85_R88_R0.8560.43
531_W535_T0.8530.43
118_A691_F0.8510.43
31_A75_K0.8500.43
21_K45_V0.8490.42
117_N175_C0.8480.42
426_T434_R0.8480.42
645_Y667_N0.8470.42
533_E536_G0.8460.42
77_L80_A0.8430.42
158_D560_E0.8430.42
150_V159_I0.8430.42
42_V75_K0.8430.42
4_H55_Q0.8410.42
49_Q57_D0.8410.42
117_N384_C0.8400.42
196_E319_G0.8380.42
25_L75_K0.8380.42
53_R64_A0.8380.42
17_S21_K0.8380.42
342_K351_Q0.8360.42
676_T684_G0.8340.41
551_D555_R0.8340.41
30_A73_P0.8330.41
226_N401_D0.8330.41
58_I84_Y0.8330.41
681_G698_E0.8330.41
44_A52_G0.8310.41
33_V67_N0.8310.41
605_F633_P0.8310.41
391_W394_E0.8280.41
509_D583_K0.8260.41
383_G405_N0.8250.41
50_M533_E0.8240.41
451_G477_S0.8220.40
42_V47_S0.8220.40
678_R682_Y0.8220.40
103_R144_H0.8190.40
695_K702_R0.8190.40
336_D341_K0.8190.40
613_N616_H0.8180.40
475_D478_E0.8170.40
36_A71_S0.8150.40
411_L572_Y0.8140.40
206_A277_E0.8140.40
68_Q72_G0.8130.40
409_I441_A0.8130.40
428_W516_K0.8130.40
159_I437_L0.8110.40
25_L33_V0.8100.40
521_V524_L0.8090.40
129_R217_S0.8080.39
48_E71_S0.8080.39
8_R84_Y0.8070.39
336_D629_Y0.8070.39
84_Y88_R0.8060.39
678_R702_R0.8060.39
184_L235_F0.8050.39
620_A626_D0.8040.39
25_L74_Y0.8020.39
24_I70_M0.7980.39
609_G635_Y0.7970.39
31_A54_N0.7970.39
14_P21_K0.7960.39
8_R88_R0.7940.38
4_H72_G0.7910.38
393_N399_I0.7890.38
58_I61_I0.7880.38
43_A81_Y0.7880.38
25_L44_A0.7880.38
644_C667_N0.7870.38
609_G624_V0.7860.38
25_L45_V0.7850.38
259_A263_T0.7850.38
65_V92_R0.7830.38
86_H89_D0.7830.38
489_L528_V0.7830.38
357_A621_L0.7830.38
205_T232_L0.7820.38
389_G393_N0.7820.38
5_V55_Q0.7820.38
67_N83_E0.7790.37
42_V77_L0.7780.37
44_A48_E0.7760.37
499_N504_G0.7740.37
607_C679_V0.7740.37
522_E599_P0.7730.37
152_Q416_I0.7680.37
46_V68_Q0.7680.37
342_K350_K0.7650.36
494_I497_T0.7650.36
336_D340_H0.7640.36
679_V699_V0.7640.36
389_G538_G0.7640.36
174_N405_N0.7630.36
368_Y379_K0.7620.36
539_F697_E0.7620.36
529_D602_N0.7600.36
4_H37_D0.7600.36
64_A67_N0.7590.36
246_T249_E0.7590.36
43_A68_Q0.7580.36
181_K185_T0.7570.36
34_D77_L0.7570.36
49_Q67_N0.7570.36
692_N698_E0.7570.36
411_L421_K0.7560.36
139_H143_Q0.7560.36
259_A269_D0.7550.36
83_E86_H0.7550.36
59_N84_Y0.7540.36
677_R699_V0.7540.36
32_E76_Q0.7540.36
180_L225_I0.7540.36
551_D694_G0.7540.36
7_K19_R0.7530.36
82_I91_E0.7530.36
323_K674_S0.7530.36
38_Y47_S0.7520.36
265_K268_Y0.7510.35
206_A209_A0.7510.35
394_E397_E0.7500.35
562_G568_T0.7500.35
56_V64_A0.7490.35
16_K58_I0.7480.35
17_S20_I0.7470.35
147_P440_K0.7460.35
52_G55_Q0.7420.35
501_L520_I0.7420.35
76_Q80_A0.7410.35
73_P79_R0.7390.35
30_A39_C0.7380.35
14_P56_V0.7360.34
147_P168_P0.7350.34
75_K82_I0.7350.34
129_R166_Y0.7340.34
8_R27_A0.7340.34
424_E502_F0.7330.34
68_Q93_E0.7320.34
677_R705_H0.7300.34
571_G700_K0.7300.34
175_C545_P0.7300.34
180_L231_V0.7300.34
6_M68_Q0.7270.34
481_K537_Y0.7270.34
70_M74_Y0.7270.34
154_H160_H0.7260.34
17_S33_V0.7260.34
149_D436_V0.7250.34
28_A32_E0.7240.34
524_L527_A0.7240.34
180_L234_P0.7240.34
315_I356_C0.7230.34
159_I434_R0.7230.34
43_A82_I0.7220.33
559_A619_K0.7210.33
128_Q131_L0.7210.33
24_I52_G0.7210.33
40_A48_E0.7210.33
532_K538_G0.7210.33
36_A41_T0.7210.33
14_P29_K0.7190.33
72_G82_I0.7190.33
191_G206_A0.7180.33
89_D93_E0.7170.33
418_L563_V0.7170.33
17_S22_E0.7160.33
12_K57_D0.7140.33
414_P417_A0.7130.33
35_D56_V0.7130.33
75_K83_E0.7120.33
135_I139_H0.7120.33
496_E574_T0.7110.33
32_E35_D0.7110.33
562_G569_D0.7100.33
180_L208_T0.7090.33
644_C665_C0.7080.33
25_L77_L0.7080.33
25_L32_E0.7070.32
57_D64_A0.7070.32
213_A217_S0.7050.32
411_L434_R0.7050.32
36_A50_M0.7040.32
587_P628_S0.7040.32
667_N673_V0.7010.32
491_Y524_L0.7010.32
87_D91_E0.7000.32
25_L35_D0.7000.32
675_V694_G0.6990.32
70_M86_H0.6980.32
225_I228_I0.6980.32
675_V684_G0.6970.32
44_A47_S0.6970.32
126_P130_D0.6970.32
82_I88_R0.6970.32
6_M75_K0.6960.32
34_D39_C0.6950.32
333_A378_F0.6950.32
18_E51_Q0.6930.32
414_P492_I0.6920.31
60_E72_G0.6920.31
224_T540_S0.6910.31
48_E52_G0.6910.31
386_S408_V0.6900.31
682_Y695_K0.6890.31
13_V47_S0.6880.31
67_N70_M0.6870.31
59_N92_R0.6860.31
411_L489_L0.6860.31
57_D77_L0.6860.31
29_K42_V0.6850.31
280_T286_G0.6840.31
19_R51_Q0.6840.31
31_A45_V0.6810.31
47_S54_N0.6800.31
142_R151_V0.6800.31
205_T270_A0.6780.31
492_I553_F0.6770.31
246_T250_W0.6760.30
9_D39_C0.6750.30
39_C50_M0.6750.30
18_E21_K0.6740.30
22_E64_A0.6740.30
6_M11_C0.6730.30
17_S48_E0.6720.30
361_M641_I0.6700.30
12_K44_A0.6690.30
131_L135_I0.6690.30
558_T669_D0.6680.30
151_V154_H0.6670.30
495_H582_E0.6660.30
6_M19_R0.6660.30
16_K21_K0.6650.30
40_A44_A0.6640.30
491_Y601_A0.6630.30
5_V16_K0.6620.30
358_S615_Q0.6620.30
180_L342_K0.6620.30
59_N90_I0.6600.29
41_T53_R0.6580.29
31_A34_D0.6580.29
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31_A74_Y0.6570.29
258_Y262_R0.6560.29
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194_E323_K0.6530.29
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679_V695_K0.6530.29
29_K51_Q0.6520.29
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186_Q197_P0.6480.29
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305_L309_S0.6470.29
31_A41_T0.6460.29
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377_S398_Q0.6440.28
524_L531_W0.6430.28
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413_L497_T0.6420.28
230_E303_S0.6420.28
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179_D189_K0.6380.28
32_E39_C0.6370.28
681_G695_K0.6350.28
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675_V680_C0.6350.28
492_I557_D0.6350.28
526_Q529_D0.6350.28
324_T362_Y0.6350.28
49_Q52_G0.6340.28
425_A429_K0.6330.28
680_C695_K0.6330.28
508_Y577_F0.6310.28
499_N502_F0.6310.28
209_A277_E0.6310.28
425_A519_A0.6300.28
41_T51_Q0.6290.28
564_V572_Y0.6290.28
27_A80_A0.6280.27
243_H259_A0.6280.27
45_V67_N0.6280.27
558_T592_D0.6280.27
14_P80_A0.6270.27
45_V54_N0.6270.27
188_F319_G0.6250.27
414_P420_A0.6250.27
67_N79_R0.6240.27
67_N73_P0.6240.27
64_A72_G0.6240.27
33_V39_C0.6230.27
355_E359_K0.6220.27
63_T67_N0.6220.27
31_A50_M0.6220.27
33_V80_A0.6210.27
282_H285_N0.6210.27
222_G383_G0.6210.27
31_A57_D0.6200.27
70_M76_Q0.6200.27
28_A43_A0.6190.27
575_N581_V0.6180.27
175_C382_M0.6180.27
566_G570_K0.6180.27
38_Y67_N0.6170.27
212_I263_T0.6170.27
28_A70_M0.6170.27
215_V402_G0.6160.27
211_I215_V0.6150.27
138_K525_R0.6150.27
14_P93_E0.6140.27
423_D666_G0.6140.27
18_E35_D0.6140.27
511_E514_R0.6140.27
621_L637_T0.6140.27
572_Y582_E0.6110.26
549_L557_D0.6110.26
34_D37_D0.6110.26
38_Y53_R0.6100.26
28_A71_S0.6090.26
16_K53_R0.6090.26
676_T685_S0.6080.26
38_Y42_V0.6070.26
28_A42_V0.6060.26
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14_P42_V0.6050.26
316_A322_R0.6040.26
410_S550_C0.6040.26
572_Y578_H0.6040.26
392_E395_N0.6030.26
39_C42_V0.6020.26
29_K36_A0.6010.26
39_C47_S0.6010.26
31_A62_Q0.6010.26
377_S391_W0.6010.26
70_M79_R0.5990.26
145_L691_F0.5980.26
129_R134_G0.5970.26
24_I64_A0.5970.26
235_F644_C0.5970.26
680_C684_G0.5970.26
34_D48_E0.5960.26
48_E64_A0.5950.26
119_N384_C0.5950.26
305_L626_D0.5950.26
492_I573_Y0.5940.25
82_I85_R0.5940.25
65_V77_L0.5940.25
22_E54_N0.5940.25
237_T478_E0.5940.25
45_V70_M0.5920.25
160_H694_G0.5920.25
62_Q70_M0.5920.25
37_D60_E0.5920.25
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679_V696_Q0.5910.25
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230_E368_Y0.5890.25
37_D54_N0.5880.25
66_E77_L0.5880.25
187_G317_G0.5870.25
295_F298_G0.5860.25
31_A47_S0.5850.25
598_P605_F0.5830.25
14_P57_D0.5830.25
518_I597_Y0.5830.25
53_R71_S0.5830.25
14_P44_A0.5820.25
116_E524_L0.5820.25
383_G386_S0.5810.25
56_V65_V0.5810.25
21_K55_Q0.5800.25
28_A90_I0.5790.25
119_N175_C0.5790.25
38_Y51_Q0.5780.25
555_R586_N0.5770.25
673_V685_S0.5770.25
52_G71_S0.5770.25
67_N80_A0.5750.24
54_N429_K0.5750.24
225_I357_A0.5740.24
607_C632_V0.5740.24
21_K87_D0.5740.24
28_A41_T0.5730.24
675_V685_S0.5730.24
388_L396_G0.5730.24
83_E91_E0.5730.24
504_G509_D0.5720.24
37_D51_Q0.5710.24
38_Y49_Q0.5710.24
18_E39_C0.5700.24
61_I420_A0.5700.24
214_Q218_H0.5700.24
392_E398_Q0.5700.24
389_G392_E0.5690.24
28_A58_I0.5680.24
74_Y90_I0.5680.24
142_R146_L0.5680.24
217_S267_C0.5680.24
9_D93_E0.5680.24
424_E428_W0.5680.24
33_V36_A0.5650.24
382_M388_L0.5650.24
336_D630_Q0.5650.24
642_D677_R0.5650.24
8_R59_N0.5650.24
281_L318_L0.5640.24
29_K32_E0.5640.24
41_T73_P0.5640.24
492_I548_N0.5640.24
21_K25_L0.5630.24
133_A166_Y0.5620.24
237_T294_G0.5620.24
62_Q77_L0.5610.24
39_C65_V0.5610.24
593_F597_Y0.5610.24
394_E532_K0.5610.24
42_V45_V0.5580.23
167_S446_I0.5580.23
391_W398_Q0.5580.23
12_K48_E0.5580.23
28_A38_Y0.5580.23
9_D41_T0.5580.23
414_P573_Y0.5570.23
17_S68_Q0.5570.23
331_V381_P0.5570.23
52_G429_K0.5560.23
178_I223_T0.5560.23
329_K364_D0.5560.23
571_G697_E0.5550.23
49_Q61_I0.5550.23
6_M37_D0.5540.23
49_Q55_Q0.5540.23
159_I435_L0.5530.23
35_D240_Y0.5530.23
174_N383_G0.5530.23
14_P60_E0.5520.23
208_T274_L0.5520.23
410_S701_R0.5510.23
44_A301_W0.5510.23
120_K130_D0.5510.23
43_A93_E0.5510.23
486_S695_K0.5500.23
151_V155_E0.5490.23
33_V75_K0.5490.23
45_V60_E0.5490.23
38_Y76_Q0.5480.23
75_K80_A0.5470.23
696_Q699_V0.5460.23
433_E586_N0.5460.23
49_Q76_Q0.5450.23
33_V71_S0.5450.23
412_N557_D0.5450.23
361_M639_T0.5440.23
40_A64_A0.5440.23
125_I219_I0.5440.23
11_C31_A0.5440.23
29_K67_N0.5440.23
678_R695_K0.5430.23
413_L491_Y0.5430.23
32_E68_Q0.5430.23
341_K622_E0.5420.23
21_K41_T0.5420.23
17_S49_Q0.5420.23
37_D52_G0.5420.23
279_N683_L0.5420.23
29_K76_Q0.5410.23
429_K440_K0.5410.23
334_I628_S0.5390.22
90_I99_N0.5390.22
550_C553_F0.5380.22
18_E36_A0.5370.22
343_G397_E0.5370.22
113_L138_K0.5350.22
123_K199_K0.5350.22
66_E87_D0.5350.22
58_I74_Y0.5350.22
5_V36_A0.5340.22
333_A367_N0.5340.22
201_I205_T0.5330.22
628_S679_V0.5330.22
619_K623_D0.5330.22
39_C90_I0.5300.22
25_L58_I0.5300.22
384_C545_P0.5300.22
429_K515_A0.5300.22
67_N156_R0.5290.22
312_R355_E0.5290.22
33_V43_A0.5280.22
155_E158_D0.5280.22
174_N222_G0.5280.22
49_Q71_S0.5280.22
120_K129_R0.5270.22
61_I92_R0.5270.22
14_P50_M0.5260.22
387_F390_V0.5260.22
220_Y542_Y0.5260.22
49_Q77_L0.5260.22
33_V83_E0.5260.22
206_A273_S0.5250.22
63_T66_E0.5250.22
622_E625_W0.5250.22
53_R76_Q0.5250.22
108_Q115_N0.5250.22
350_K354_L0.5250.22
25_L55_Q0.5250.22
58_I86_H0.5240.22
294_G299_T0.5240.22
50_M60_E0.5240.22
204_A327_F0.5240.22
224_T331_V0.5240.22
80_A145_L0.5230.22
258_Y261_S0.5230.22
41_T67_N0.5230.22
36_A44_A0.5220.22
306_I570_K0.5220.22
645_Y674_S0.5220.22
405_N540_S0.5220.22
421_K530_Q0.5210.22
664_K668_H0.5210.22
416_I497_T0.5210.22
208_T250_W0.5210.22
138_K311_L0.5210.22
64_A74_Y0.5210.22
342_K447_A0.5210.22
93_E101_E0.5200.21
236_V267_C0.5200.21
589_D593_F0.5200.21
146_L586_N0.5190.21
350_K622_E0.5190.21
393_N482_N0.5190.21
432_D436_V0.5190.21
556_L559_A0.5190.21
30_A50_M0.5190.21
106_V115_N0.5180.21
182_G186_Q0.5180.21
17_S72_G0.5180.21
36_A48_E0.5180.21
23_A59_N0.5180.21
29_K44_A0.5170.21
357_A365_I0.5170.21
25_L71_S0.5170.21
318_L474_D0.5150.21
523_R526_Q0.5150.21
329_K636_G0.5150.21
40_A75_K0.5150.21
297_L368_Y0.5140.21
31_A37_D0.5140.21
674_S679_V0.5140.21
414_P550_C0.5130.21
31_A38_Y0.5130.21
20_I62_Q0.5120.21
58_I82_I0.5110.21
198_P204_A0.5110.21
634_Y663_P0.5100.21
34_D70_M0.5090.21
623_D627_Y0.5090.21
141_A168_P0.5090.21
56_V411_L0.5090.21
77_L86_H0.5090.21
73_P77_L0.5080.21
499_N582_E0.5080.21
25_L61_I0.5080.21
210_Q408_V0.5080.21
4_H80_A0.5070.21
11_C41_T0.5060.21
677_R685_S0.5060.21
592_D666_G0.5060.21
205_T271_F0.5050.21
181_K227_R0.5050.21
609_G637_T0.5050.21
34_D38_Y0.5040.21
22_E51_Q0.5040.21
26_R30_A0.5040.21
115_N561_F0.5040.21
181_K234_P0.5040.21
25_L76_Q0.5030.21
29_K34_D0.5030.21
27_A66_E0.5030.21
6_M22_E0.5030.21
40_A54_N0.5030.21
432_D511_E0.5020.21
245_K312_R0.5020.21
180_L692_N0.5020.21
327_F545_P0.5020.21
424_E511_E0.5020.21
240_Y305_L0.5020.21
439_R527_A0.5010.21
154_H414_P0.5010.21
222_G386_S0.5010.21
141_A167_S0.5010.21
33_V44_A0.5000.20
417_A500_A0.5000.20
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1h7bA 2 0.7416 100 0.255 Contact Map
4u3eA 2 0.8287 100 0.383 Contact Map
1r9dA 2 0.8455 99.8 0.921 Contact Map
2y8nA 2 0.8525 99.7 0.927 Contact Map
3hncA 2 0.7795 99.5 0.934 Contact Map
2f3oA 3 0.8104 99.4 0.938 Contact Map
3k8tA 2 0.6629 99.4 0.939 Contact Map
5a0uA 2 0.861 99.4 0.94 Contact Map
1h16A 2 0.8567 99.3 0.941 Contact Map
2xapA 4 0.7935 99.1 0.946 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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