NARQ - ECOLI - GREMLIN Contacts

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NARQ - Nitrate/nitrite sensor protein NarQ

UniProt:	P27896	Sequences: MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAINIAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHLNANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIGIFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTNLPNELGLLAKTFNQMSSELHKLYRSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRDNEAAEYLELNVGENWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLNSVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIPEDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAKLTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRDNGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11460
Length:	566 (520)
Sequences:	7929 (7001)
Seq/√Len:	307.0

ECOLI - NARQ NARX ATOS BARA TORS RCSC RCSD ARCB DPIB DCUS BAES GLRK CREC PHOQ CUSS PHOR
BACSU - RESE YYCG PHOR MALK DCTS CITS KINE YCLK KINC KINA YVRG YKOH CSSS
HALSA - Q9HQ16 Q9HQG5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
189_R	194_Q	5.150	1.00
204_L	209_G	4.327	1.00
544_P	547_G	4.083	1.00
507_R	550_L	3.870	1.00
262_I	266_C	3.470	1.00
206_N	209_G	3.372	1.00
199_P	223_H	3.287	1.00
384_L	405_F	3.211	1.00
485_A	509_N	3.173	1.00
187_S	218_M	3.099	1.00
199_P	216_N	2.898	1.00
10_S	206_N	2.883	1.00
541_F	551_V	2.795	1.00
452_T	489_E	2.650	1.00
6_P	9_A	2.539	1.00
190_I	218_M	2.538	1.00
491_A	507_R	2.534	1.00
504_V	553_I	2.458	1.00
190_I	219_S	2.454	1.00
493_S	505_Y	2.446	1.00
473_I	531_R	2.389	1.00
497_A	503_T	2.383	1.00
489_E	509_N	2.381	1.00
540_T	552_S	2.373	1.00
465_Q	535_L	2.338	1.00
501_N	554_S	2.307	1.00
367_R	370_H	2.292	1.00
431_D	434_S	2.288	1.00
384_L	388_K	2.284	1.00
529_R	533_E	2.270	1.00
454_D	493_S	2.261	1.00
473_I	532_A	2.249	1.00
364_T	367_R	2.215	1.00
199_P	219_S	2.202	1.00
128_Y	132_I	2.172	1.00
244_K	248_E	2.165	1.00
495_V	503_T	2.158	1.00
532_A	553_I	2.158	1.00
360_E	363_A	2.137	1.00
187_S	215_F	2.123	1.00
256_A	337_S	2.120	1.00
377_L	383_Q	2.085	1.00
376_V	387_L	2.070	1.00
183_L	212_A	2.051	1.00
199_P	220_S	2.050	1.00
377_L	384_L	2.041	1.00
359_M	363_A	2.039	1.00
505_Y	550_L	2.024	1.00
493_S	507_R	1.995	1.00
485_A	488_S	1.979	1.00
542_S	550_L	1.928	1.00
422_T	426_T	1.925	1.00
363_A	366_A	1.919	1.00
183_L	215_F	1.911	1.00
187_S	214_T	1.902	1.00
528_M	539_L	1.902	1.00
430_A	465_Q	1.898	1.00
248_E	252_Q	1.880	1.00
543_Q	546_G	1.879	1.00
362_R	366_A	1.868	1.00
503_T	554_S	1.849	1.00
377_L	387_L	1.845	1.00
359_M	365_I	1.844	1.00
184_V	210_L	1.827	1.00
532_A	537_G	1.824	1.00
505_Y	552_S	1.823	1.00
359_M	366_A	1.803	1.00
169_L	173_R	1.793	1.00
189_R	197_S	1.790	1.00
531_R	535_L	1.781	1.00
377_L	388_K	1.774	1.00
362_R	365_I	1.771	1.00
543_Q	549_T	1.763	1.00
89_W	92_P	1.763	1.00
433_P	494_C	1.763	1.00
481_A	490_I	1.750	1.00
27_G	31_L	1.723	1.00
465_Q	470_L	1.722	1.00
216_N	219_S	1.721	1.00
543_Q	547_G	1.720	1.00
119_P	124_N	1.709	1.00
361_E	365_I	1.705	1.00
173_R	177_V	1.698	1.00
454_D	491_A	1.686	1.00
394_D	398_A	1.665	1.00
379_Y	383_Q	1.660	1.00
186_A	200_L	1.655	1.00
92_P	96_K	1.647	1.00
503_T	552_S	1.645	1.00
452_T	491_A	1.642	1.00
376_V	383_Q	1.614	1.00
335_S	340_L	1.600	1.00
435_A	439_M	1.600	1.00
273_I	276_D	1.591	1.00
474_I	504_V	1.589	1.00
187_S	211_L	1.585	1.00
196_D	223_H	1.583	1.00
42_A	45_I	1.578	1.00
184_V	214_T	1.565	1.00
387_L	391_I	1.565	1.00
488_S	509_N	1.556	1.00
508_D	512_G	1.552	1.00
188_Q	210_L	1.548	1.00
215_F	218_M	1.544	1.00
359_M	362_R	1.544	1.00
361_E	366_A	1.537	1.00
495_V	505_Y	1.521	1.00
449_A	453_L	1.518	1.00
88_V	92_P	1.517	1.00
200_L	216_N	1.516	1.00
318_E	321_W	1.515	1.00
363_A	368_E	1.510	1.00
376_V	384_L	1.483	1.00
538_T	554_S	1.482	1.00
272_Q	276_D	1.470	1.00
118_L	122_Q	1.459	1.00
369_L	377_L	1.455	1.00
376_V	379_Y	1.448	1.00
318_E	323_N	1.417	1.00
132_I	139_L	1.414	1.00
450_K	489_E	1.400	1.00
388_K	403_A	1.376	1.00
366_A	369_L	1.366	1.00
469_H	472_Q	1.365	1.00
379_Y	384_L	1.364	1.00
491_A	509_N	1.362	1.00
267_F	274_V	1.352	1.00
283_L	286_N	1.341	1.00
41_E	45_I	1.340	1.00
479_L	483_K	1.338	1.00
422_T	425_L	1.336	1.00
94_A	98_R	1.327	1.00
174_H	178_A	1.327	1.00
205_P	209_G	1.318	1.00
240_L	243_A	1.318	1.00
437_R	441_D	1.316	1.00
295_E	298_P	1.314	1.00
533_E	538_T	1.310	1.00
360_E	364_T	1.300	1.00
259_T	274_V	1.299	1.00
93_E	96_K	1.283	1.00
179_P	207_E	1.282	1.00
403_A	407_Q	1.280	1.00
46_A	49_L	1.273	1.00
200_L	212_A	1.269	1.00
514_G	545_S	1.266	1.00
501_N	538_T	1.265	1.00
194_Q	197_S	1.260	1.00
395_N	398_A	1.256	1.00
266_C	269_H	1.254	1.00
10_S	175_Q	1.250	1.00
317_G	323_N	1.247	1.00
360_E	368_E	1.247	1.00
119_P	122_Q	1.242	1.00
383_Q	387_L	1.241	1.00
473_I	528_M	1.239	1.00
421_T	424_R	1.238	1.00
8_S	12_A	1.230	1.00
299_N	302_L	1.225	1.00
257_L	277_N	1.219	1.00
542_S	552_S	1.218	1.00
186_A	215_F	1.217	1.00
320_H	324_S	1.215	1.00
257_L	271_L	1.210	1.00
102_L	106_W	1.209	1.00
363_A	370_H	1.209	1.00
434_S	438_E	1.205	1.00
241_H	244_K	1.202	1.00
469_H	531_R	1.200	1.00
280_A	284_E	1.200	1.00
433_P	437_R	1.200	1.00
155_L	159_I	1.189	1.00
54_Y	57_G	1.187	1.00
429_Q	464_A	1.183	1.00
132_I	135_F	1.182	1.00
412_A	415_Q	1.180	1.00
165_V	169_L	1.179	1.00
331_P	334_N	1.178	1.00
431_D	435_A	1.177	1.00
188_Q	217_Q	1.175	1.00
414_R	418_E	1.174	1.00
361_E	370_H	1.172	1.00
302_L	305_Q	1.171	1.00
272_Q	275_R	1.170	1.00
259_T	267_F	1.168	1.00
184_V	188_Q	1.166	1.00
334_N	338_S	1.161	1.00
319_L	322_Q	1.161	1.00
256_A	259_T	1.161	1.00
68_N	72_Q	1.160	1.00
485_A	490_I	1.158	1.00
56_L	60_L	1.158	1.00
230_E	237_T	1.156	1.00
400_S	403_A	1.155	1.00
46_A	50_R	1.153	1.00
381_R	384_L	1.153	1.00
381_R	387_L	1.151	1.00
377_L	381_R	1.150	1.00
47_G	50_R	1.150	1.00
438_E	471_L	1.149	1.00
275_R	282_Y	1.142	1.00
15_F	18_I	1.141	1.00
127_N	130_N	1.138	1.00
376_V	388_K	1.137	1.00
436_L	474_I	1.135	1.00
54_Y	58_Y	1.133	1.00
388_K	399_Q	1.132	1.00
130_N	134_L	1.129	1.00
381_R	409_L	1.127	1.00
466_M	469_H	1.122	1.00
319_L	323_N	1.120	1.00
253_C	257_L	1.119	1.00
153_I	156_A	1.113	1.00
316_Y	323_N	1.113	1.00
377_L	380_L	1.110	1.00
92_P	102_L	1.108	1.00
293_I	297_Q	1.100	1.00
212_A	216_N	1.097	1.00
470_L	535_L	1.096	1.00
361_E	367_R	1.096	1.00
311_M	315_V	1.095	1.00
250_L	260_S	1.095	1.00
274_V	277_N	1.094	1.00
186_A	197_S	1.094	1.00
474_I	506_I	1.092	1.00
409_L	412_A	1.084	1.00
317_G	322_Q	1.084	1.00
362_R	368_E	1.078	1.00
271_L	274_V	1.076	1.00
331_P	335_S	1.074	1.00
537_G	555_F	1.074	1.00
406_S	410_N	1.067	1.00
365_I	369_L	1.066	1.00
362_R	369_L	1.062	1.00
515_E	544_P	1.061	1.00
376_V	380_L	1.057	1.00
218_M	222_L	1.057	1.00
263_D	266_C	1.057	1.00
202_T	216_N	1.053	1.00
134_L	139_L	1.051	1.00
376_V	391_I	1.048	1.00
388_K	406_S	1.043	1.00
32_T	35_S	1.043	1.00
250_L	257_L	1.035	1.00
455_C	494_C	1.034	1.00
359_M	370_H	1.033	1.00
363_A	367_R	1.032	1.00
321_W	324_S	1.031	1.00
42_A	46_A	1.028	1.00
409_L	415_Q	1.028	1.00
315_V	323_N	1.028	1.00
14_A	18_I	1.028	1.00
273_I	277_N	1.027	1.00
458_P	496_T	1.026	1.00
308_P	311_M	1.025	1.00
337_S	340_L	1.024	1.00
176_V	179_P	1.023	1.00
243_A	246_R	1.023	1.00
132_I	136_V	1.022	1.00
243_A	247_L	1.022	1.00
354_Q	358_L	1.021	1.00
237_T	241_H	1.021	1.00
182_Q	201_D	1.020	1.00
281_E	284_E	1.018	1.00
127_N	132_I	1.017	1.00
56_L	59_D	1.016	1.00
434_S	437_R	1.015	1.00
118_L	124_N	1.012	1.00
59_D	62_S	1.011	1.00
394_D	397_T	1.010	1.00
328_S	331_P	1.007	1.00
188_Q	192_H	1.007	1.00
420_L	426_T	1.006	1.00
45_I	49_L	1.006	1.00
270_I	277_N	1.005	1.00
335_S	338_S	1.002	1.00
57_G	60_L	1.001	1.00
316_Y	324_S	0.997	1.00
388_K	391_I	0.996	1.00
195_F	218_M	0.993	1.00
472_Q	531_R	0.993	1.00
277_N	284_E	0.990	1.00
318_E	322_Q	0.985	1.00
28_I	32_T	0.983	1.00
93_E	97_T	0.983	1.00
316_Y	319_L	0.979	1.00
513_I	549_T	0.978	1.00
384_L	391_I	0.976	1.00
413_Y	417_R	0.976	1.00
58_Y	62_S	0.973	1.00
497_A	554_S	0.973	1.00
375_Q	379_Y	0.970	1.00
126_N	130_N	0.968	1.00
410_N	414_R	0.968	1.00
254_S	257_L	0.968	1.00
70_H	73_L	0.966	1.00
97_T	101_H	0.965	1.00
57_G	61_Q	0.965	1.00
383_Q	388_K	0.962	1.00
271_L	277_N	0.959	1.00
224_K	228_S	0.958	1.00
210_L	213_K	0.956	1.00
250_L	255_Q	0.956	1.00
282_Y	286_N	0.954	1.00
8_S	173_R	0.952	1.00
532_A	555_F	0.950	1.00
540_T	554_S	0.949	1.00
362_R	370_H	0.948	1.00
242_E	246_R	0.947	1.00
239_D	242_E	0.947	1.00
251_Y	258_N	0.942	1.00
49_L	53_S	0.938	1.00
183_L	187_S	0.938	1.00
95_V	98_R	0.936	1.00
414_R	468_V	0.935	1.00
376_V	381_R	0.934	1.00
303_P	306_I	0.932	1.00
377_L	391_I	0.930	1.00
49_L	52_Q	0.928	1.00
90_Y	93_E	0.928	1.00
139_L	142_Y	0.926	1.00
421_T	425_L	0.926	1.00
96_K	100_A	0.925	1.00
440_L	444_Q	0.925	1.00
89_W	95_V	0.925	1.00
474_I	478_V	0.925	1.00
98_R	102_L	0.924	1.00
103_N	107_L	0.923	1.00
379_Y	387_L	0.920	1.00
267_F	270_I	0.915	1.00
473_I	535_L	0.912	1.00
128_Y	134_L	0.906	1.00
541_F	549_T	0.904	1.00
321_W	325_H	0.903	1.00
473_I	553_I	0.902	1.00
79_H	82_V	0.901	1.00
183_L	208_L	0.900	1.00
97_T	100_A	0.898	1.00
202_T	213_K	0.898	1.00
257_L	260_S	0.896	1.00
440_L	443_L	0.894	1.00
284_E	287_V	0.893	1.00
270_I	274_V	0.891	1.00
305_Q	308_P	0.891	1.00
387_L	390_S	0.890	1.00
420_L	424_R	0.887	1.00
436_L	492_V	0.886	1.00
443_L	475_R	0.884	1.00
7_V	176_V	0.882	1.00
254_S	258_N	0.880	1.00
270_I	273_I	0.880	1.00
104_A	108_E	0.879	1.00
470_L	553_I	0.879	1.00
435_A	443_L	0.878	1.00
463_D	555_F	0.878	1.00
359_M	368_E	0.877	1.00
69_A	72_Q	0.876	1.00
140_Q	144_E	0.874	1.00
131_Q	134_L	0.874	1.00
399_Q	403_A	0.873	1.00
412_A	425_L	0.872	1.00
265_H	271_L	0.872	1.00
43_I	46_A	0.872	1.00
360_E	365_I	0.870	1.00
148_L	152_A	0.870	1.00
359_M	367_R	0.870	1.00
263_D	270_I	0.868	1.00
251_Y	271_L	0.868	1.00
251_Y	254_S	0.864	1.00
494_C	504_V	0.864	1.00
408_A	411_D	0.861	1.00
261_Q	267_F	0.860	1.00
540_T	553_I	0.860	1.00
477_A	528_M	0.859	1.00
152_A	156_A	0.859	1.00
26_T	158_G	0.855	1.00
221_E	224_K	0.855	1.00
261_Q	266_C	0.854	1.00
435_A	438_E	0.852	1.00
400_S	404_D	0.851	1.00
364_T	368_E	0.850	1.00
361_E	368_E	0.849	1.00
129_V	132_I	0.849	1.00
159_I	163_T	0.846	1.00
247_L	251_Y	0.845	1.00
269_H	272_Q	0.844	1.00
202_T	212_A	0.843	1.00
295_E	299_N	0.843	1.00
261_Q	265_H	0.842	1.00
477_A	551_V	0.841	1.00
367_R	376_V	0.839	1.00
331_P	340_L	0.837	1.00
320_H	323_N	0.837	1.00
414_R	417_R	0.835	1.00
24_L	28_I	0.835	1.00
217_Q	221_E	0.834	1.00
358_L	362_R	0.833	1.00
312_Q	316_Y	0.832	1.00
381_R	410_N	0.831	1.00
249_V	253_C	0.829	1.00
478_V	492_V	0.829	1.00
412_A	416_L	0.827	1.00
250_L	254_S	0.826	1.00
141_H	145_R	0.824	1.00
304_M	307_L	0.823	1.00
95_V	99_Y	0.822	1.00
151_V	155_L	0.822	1.00
359_M	369_L	0.821	1.00
255_Q	259_T	0.820	1.00
366_A	375_Q	0.819	1.00
292_R	296_G	0.816	1.00
120_W	124_N	0.816	1.00
263_D	267_F	0.815	1.00
296_G	300_P	0.815	1.00
411_D	415_Q	0.813	1.00
339_M	342_R	0.812	1.00
251_Y	257_L	0.810	1.00
211_L	215_F	0.809	1.00
438_E	467_Q	0.809	1.00
7_V	208_L	0.805	1.00
387_L	398_A	0.803	1.00
250_L	258_N	0.800	1.00
117_D	120_W	0.799	1.00
266_C	270_I	0.798	1.00
429_Q	433_P	0.796	1.00
432_L	502_H	0.795	1.00
456_R	495_V	0.793	1.00
439_M	443_L	0.792	1.00
439_M	442_T	0.792	1.00
90_Y	94_A	0.790	1.00
223_H	227_R	0.787	1.00
484_H	518_E	0.784	1.00
262_I	265_H	0.783	0.99
120_W	123_A	0.783	0.99
334_N	340_L	0.782	0.99
128_Y	131_Q	0.781	0.99
58_Y	61_Q	0.781	0.99
35_S	39_D	0.780	0.99
365_I	368_E	0.779	0.99
135_F	139_L	0.776	0.99
67_L	70_H	0.775	0.99
435_A	442_T	0.774	0.99
265_H	268_R	0.772	0.99
505_Y	553_I	0.771	0.99
353_F	357_L	0.769	0.99
274_V	281_E	0.766	0.99
439_M	478_V	0.765	0.99
274_V	278_E	0.764	0.99
446_Q	449_A	0.762	0.99
443_L	482_M	0.762	0.99
45_I	48_S	0.760	0.99
238_R	242_E	0.759	0.99
184_V	211_L	0.759	0.99
89_W	93_E	0.759	0.99
477_A	553_I	0.757	0.99
118_L	125_I	0.757	0.99
267_F	277_N	0.752	0.99
92_P	98_R	0.749	0.99
7_V	180_L	0.748	0.99
247_L	250_L	0.747	0.99
146_K	150_V	0.743	0.99
413_Y	416_L	0.743	0.99
316_Y	322_Q	0.742	0.99
380_L	405_F	0.740	0.99
30_L	34_A	0.739	0.99
34_A	37_L	0.738	0.99
19_V	165_V	0.738	0.99
532_A	539_L	0.738	0.99
316_Y	320_H	0.736	0.99
95_V	102_L	0.736	0.99
424_R	428_Q	0.735	0.99
477_A	506_I	0.734	0.99
28_I	31_L	0.732	0.99
119_P	123_A	0.731	0.99
201_D	216_N	0.731	0.99
18_I	165_V	0.730	0.99
219_S	223_H	0.730	0.99
317_G	320_H	0.729	0.99
417_R	421_T	0.729	0.99
67_L	71_R	0.726	0.99
237_T	240_L	0.726	0.99
505_Y	542_S	0.725	0.99
454_D	495_V	0.724	0.99
127_N	131_Q	0.724	0.99
53_S	56_L	0.721	0.99
433_P	455_C	0.720	0.99
253_C	259_T	0.719	0.99
148_L	151_V	0.717	0.99
306_I	312_Q	0.717	0.99
476_E	521_G	0.716	0.99
22_S	25_S	0.716	0.99
442_T	475_R	0.712	0.99
383_Q	401_I	0.710	0.99
347_N	350_Q	0.708	0.99
251_Y	260_S	0.704	0.99
241_H	245_R	0.704	0.99
98_R	101_H	0.703	0.99
355_Q	358_L	0.702	0.99
419_L	423_F	0.702	0.99
53_S	60_L	0.701	0.99
317_G	321_W	0.700	0.99
447_T	451_L	0.698	0.99
218_M	221_E	0.697	0.99
314_T	317_G	0.694	0.99
314_T	322_Q	0.694	0.99
438_E	441_D	0.694	0.99
244_K	247_L	0.693	0.99
436_L	494_C	0.693	0.99
135_F	138_A	0.691	0.99
348_Q	351_K	0.691	0.99
303_P	307_L	0.689	0.99
363_A	369_L	0.688	0.99
470_L	474_I	0.686	0.99
103_N	106_W	0.686	0.99
330_E	334_N	0.684	0.99
318_E	325_H	0.683	0.99
117_D	121_Y	0.682	0.99
139_L	143_A	0.682	0.99
55_R	59_D	0.681	0.99
8_S	174_H	0.680	0.99
322_Q	325_H	0.680	0.99
360_E	369_L	0.679	0.99
48_S	52_Q	0.679	0.99
415_Q	423_F	0.678	0.99
79_H	83_L	0.678	0.99
405_F	409_L	0.678	0.99
29_A	33_L	0.678	0.99
474_I	553_I	0.677	0.99
195_F	222_L	0.677	0.99
333_L	340_L	0.677	0.99
381_R	388_K	0.674	0.98
53_S	57_G	0.674	0.98
262_I	268_R	0.673	0.98
402_M	420_L	0.673	0.98
293_I	296_G	0.673	0.98
298_P	302_L	0.673	0.98
136_V	139_L	0.672	0.98
355_Q	359_M	0.672	0.98
362_R	367_R	0.672	0.98
48_S	51_M	0.671	0.98
183_L	211_L	0.671	0.98
257_L	274_V	0.670	0.98
83_L	87_N	0.669	0.98
106_W	109_M	0.667	0.98
358_L	363_A	0.667	0.98
439_M	471_L	0.667	0.98
461_A	496_T	0.665	0.98
409_L	422_T	0.664	0.98
296_G	299_N	0.661	0.98
358_L	361_E	0.660	0.98
409_L	413_Y	0.660	0.98
213_K	216_N	0.659	0.98
251_Y	269_H	0.658	0.98
275_R	279_A	0.657	0.98
402_M	426_T	0.657	0.98
271_L	275_R	0.654	0.98
257_L	336_V	0.654	0.98
117_D	124_N	0.653	0.98
384_L	409_L	0.653	0.98
250_L	253_C	0.652	0.98
88_V	91_V	0.651	0.98
484_H	511_I	0.650	0.98
25_S	29_A	0.649	0.98
262_I	271_L	0.648	0.98
149_L	153_I	0.648	0.98
314_T	323_N	0.647	0.98
133_D	137_L	0.647	0.98
152_A	155_L	0.646	0.98
89_W	102_L	0.645	0.98
252_Q	256_A	0.644	0.98
196_D	219_S	0.644	0.98
19_V	22_S	0.644	0.98
331_P	338_S	0.643	0.98
161_I	165_V	0.643	0.98
511_I	518_E	0.643	0.98
354_Q	357_L	0.641	0.98
265_H	269_H	0.641	0.98
408_A	412_A	0.640	0.98
143_A	147_M	0.639	0.98
295_E	302_L	0.639	0.98
44_N	47_G	0.638	0.98
471_L	475_R	0.638	0.98
275_R	285_L	0.637	0.98
312_Q	319_L	0.637	0.98
175_Q	179_P	0.635	0.98
511_I	549_T	0.634	0.98
100_A	103_N	0.632	0.98
68_N	71_R	0.631	0.98
26_T	29_A	0.630	0.98
360_E	366_A	0.629	0.98
265_H	273_I	0.629	0.98
92_P	106_W	0.628	0.98
319_L	324_S	0.627	0.98
294_S	297_Q	0.626	0.98
380_L	383_Q	0.623	0.98
162_F	165_V	0.620	0.97
259_T	271_L	0.619	0.97
435_A	440_L	0.619	0.97
206_N	212_A	0.619	0.97
101_H	105_N	0.619	0.97
318_E	324_S	0.618	0.97
219_S	222_L	0.617	0.97
314_T	318_E	0.614	0.97
186_A	216_N	0.614	0.97
14_A	21_L	0.614	0.97
37_L	147_M	0.614	0.97
368_E	379_Y	0.613	0.97
523_Y	527_I	0.613	0.97
398_A	402_M	0.613	0.97
350_Q	353_F	0.610	0.97
361_E	484_H	0.609	0.97
485_A	511_I	0.609	0.97
383_Q	404_D	0.608	0.97
335_S	339_M	0.608	0.97
320_H	325_H	0.607	0.97
177_V	181_N	0.607	0.97
96_K	106_W	0.606	0.97
436_L	443_L	0.604	0.97
263_D	274_V	0.604	0.97
396_A	400_S	0.602	0.97
343_G	360_E	0.601	0.97
131_Q	139_L	0.601	0.97
469_H	534_R	0.601	0.97
312_Q	315_V	0.601	0.97
99_Y	106_W	0.601	0.97
52_Q	55_R	0.600	0.97
420_L	425_L	0.600	0.97
368_E	375_Q	0.598	0.97
180_L	211_L	0.597	0.97
429_Q	432_L	0.597	0.97
497_A	501_N	0.596	0.97
513_I	551_V	0.595	0.97
380_L	391_I	0.594	0.97
366_A	370_H	0.592	0.97
259_T	334_N	0.592	0.97
262_I	270_I	0.591	0.97
415_Q	426_T	0.591	0.97
310_T	314_T	0.591	0.97
42_A	50_R	0.591	0.97
384_L	387_L	0.591	0.97
33_L	36_S	0.590	0.97
369_L	379_Y	0.590	0.97
402_M	415_Q	0.586	0.96
188_Q	214_T	0.586	0.96
221_E	225_L	0.585	0.96
378_S	383_Q	0.584	0.96
78_L	81_P	0.584	0.96
261_Q	270_I	0.583	0.96
460_L	463_D	0.580	0.96
431_D	461_A	0.579	0.96
369_L	380_L	0.579	0.96
117_D	125_I	0.579	0.96
450_K	487_A	0.579	0.96
95_V	106_W	0.578	0.96
39_D	43_I	0.578	0.96
415_Q	422_T	0.578	0.96
380_L	384_L	0.576	0.96
211_L	218_M	0.575	0.96
421_T	428_Q	0.575	0.96
269_H	277_N	0.573	0.96
137_L	141_H	0.573	0.96
132_I	140_Q	0.573	0.96
119_P	125_I	0.571	0.96
316_Y	321_W	0.571	0.96
141_H	144_E	0.571	0.96
369_L	376_V	0.570	0.96
383_Q	390_S	0.568	0.96
378_S	382_I	0.568	0.96
353_F	358_L	0.568	0.96
118_L	123_A	0.568	0.96
36_S	40_A	0.568	0.96
101_H	104_A	0.567	0.96
51_M	54_Y	0.566	0.96
309_V	312_Q	0.565	0.96
181_N	184_V	0.564	0.96
118_L	121_Y	0.563	0.95
8_S	181_N	0.563	0.95
302_L	306_I	0.561	0.95
126_N	133_D	0.561	0.95
311_M	314_T	0.560	0.95
360_E	370_H	0.560	0.95
210_L	214_T	0.560	0.95
513_I	525_L	0.560	0.95
314_T	320_H	0.560	0.95
369_L	383_Q	0.556	0.95
434_S	467_Q	0.556	0.95
134_L	138_A	0.552	0.95
458_P	461_A	0.552	0.95
42_A	49_L	0.550	0.95
225_L	229_L	0.549	0.95
250_L	271_L	0.548	0.95
402_M	405_F	0.547	0.95
106_W	113_L	0.547	0.95
114_S	118_L	0.547	0.95
89_W	94_A	0.547	0.95
378_S	381_R	0.547	0.95
450_K	453_L	0.546	0.95
102_L	105_N	0.545	0.95
302_L	309_V	0.544	0.95
275_R	281_E	0.544	0.95
432_L	504_V	0.542	0.94
353_F	356_L	0.541	0.94
297_Q	300_P	0.541	0.94
116_G	120_W	0.540	0.94
132_I	138_A	0.537	0.94
436_L	439_M	0.537	0.94
136_V	143_A	0.537	0.94
343_G	347_N	0.537	0.94
137_L	140_Q	0.536	0.94
483_K	518_E	0.536	0.94
308_P	315_V	0.534	0.94
266_C	273_I	0.534	0.94
307_L	311_M	0.533	0.94
253_C	258_N	0.533	0.94
99_Y	103_N	0.532	0.94
176_V	208_L	0.532	0.94
418_E	424_R	0.531	0.94
256_A	260_S	0.531	0.94
370_H	376_V	0.531	0.94
402_M	422_T	0.530	0.94
401_I	405_F	0.530	0.94
268_R	271_L	0.530	0.94
381_R	385_T	0.530	0.94
408_A	420_L	0.529	0.94
270_I	275_R	0.529	0.94
92_P	95_V	0.528	0.94
334_N	337_S	0.528	0.94
376_V	412_A	0.527	0.94
180_L	208_L	0.527	0.94
380_L	409_L	0.527	0.94
387_L	402_M	0.527	0.94
182_Q	185_T	0.526	0.94
467_Q	471_L	0.525	0.94
238_R	241_H	0.524	0.93
104_A	107_L	0.523	0.93
41_E	44_N	0.523	0.93
356_L	360_E	0.523	0.93
50_R	53_S	0.523	0.93
91_V	94_A	0.523	0.93
179_P	208_L	0.520	0.93
51_M	55_R	0.519	0.93
334_N	339_M	0.518	0.93
357_L	365_I	0.518	0.93
226_Y	229_L	0.518	0.93
262_I	277_N	0.517	0.93
295_E	319_L	0.516	0.93
132_I	143_A	0.515	0.93
96_K	109_M	0.515	0.93
308_P	318_E	0.514	0.93
252_Q	257_L	0.514	0.93
354_Q	365_I	0.514	0.93
170_R	174_H	0.513	0.93
214_T	218_M	0.513	0.93
298_P	301_E	0.513	0.93
100_A	104_A	0.513	0.93
511_I	543_Q	0.512	0.93
333_L	337_S	0.511	0.93
136_V	140_Q	0.511	0.93
483_K	517_K	0.511	0.93
326_V	329_S	0.511	0.93
543_Q	550_L	0.510	0.93
299_N	305_Q	0.510	0.93
29_A	36_S	0.509	0.92
366_A	380_L	0.509	0.92
404_D	408_A	0.508	0.92
89_W	96_K	0.508	0.92
88_V	102_L	0.508	0.92
398_A	401_I	0.507	0.92
89_W	98_R	0.507	0.92
361_E	369_L	0.506	0.92
249_V	252_Q	0.506	0.92
40_A	43_I	0.505	0.92
255_Q	258_N	0.502	0.92
32_T	36_S	0.502	0.92
134_L	137_L	0.502	0.92
421_T	469_H	0.502	0.92
47_G	51_M	0.502	0.92
263_D	281_E	0.500	0.92
36_S	39_D	0.500	0.92
19_V	169_L	0.500	0.92

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.6325	100	0.443	Contact Map
3a0rA	2	0.5371	100	0.543	Contact Map
4gczA	2	0.5883	100	0.558	Contact Map
4bixA	2	0.3675	100	0.601	Contact Map
4r3aA	1	0.5141	100	0.603	Contact Map
4ctiA	2	0.3958	100	0.622	Contact Map
2q8gA	2	0.4929	100	0.646	Contact Map
4mpcA	2	0.5053	100	0.651	Contact Map
4q20A	2	0.3675	100	0.653	Contact Map
2c2aA	2	0.3781	100	0.654	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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