TATD - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

TATD - Tat-linked quality control protein TatD

UniProt:	P27859	Sequences: MFDIGVNLTSSQFAKDRDDVVACAFDAGVNGLLITGTNLRESQQAQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFSTPEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREEMQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSSRRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11481
Length:	260 (250)
Sequences:	7104 (5051)
Seq/√Len:	319.4

ECOLI - TATD YJJV YCFH
BACSU - YABD
SULSO - Q981A2 Q97ZA2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
78_I	119_D	3.329	1.00
111_V	141_P	3.118	1.00
232_R	235_H	2.760	1.00
158_R	192_L	2.723	1.00
96_F	134_R	2.574	1.00
50_R	83_Q	2.502	1.00
23_C	222_E	2.399	1.00
114_L	124_V	2.392	1.00
149_A	169_I	2.208	1.00
250_A	254_T	2.187	1.00
140_E	163_A	2.134	1.00
231_Q	241_A	2.127	1.00
187_R	232_R	2.068	1.00
107_E	134_R	1.963	1.00
128_C	135_F	1.947	1.00
81_A	89_I	1.901	1.00
115_R	142_W	1.878	1.00
58_T	88_A	1.865	1.00
22_A	26_D	1.844	1.00
14_A	17_R	1.838	1.00
239_E	244_L	1.835	1.00
16_D	220_R	1.832	1.00
6_V	32_L	1.825	1.00
195_A	237_R	1.825	1.00
195_A	247_T	1.824	1.00
246_A	250_A	1.817	1.00
111_V	142_W	1.792	1.00
49_A	57_S	1.751	1.00
190_L	233_I	1.745	1.00
133_E	137_T	1.731	1.00
96_F	103_P	1.730	1.00
58_T	125_F	1.727	1.00
230_L	241_A	1.717	1.00
25_F	54_S	1.717	1.00
195_A	239_E	1.691	1.00
140_E	167_H	1.690	1.00
158_R	162_Q	1.661	1.00
108_R	112_A	1.659	1.00
200_I	230_L	1.659	1.00
57_S	86_V	1.650	1.00
153_C	174_T	1.642	1.00
92_C	113_Q	1.620	1.00
31_G	56_W	1.616	1.00
151_L	164_C	1.615	1.00
163_A	166_A	1.611	1.00
31_G	253_K	1.607	1.00
4_I	252_V	1.594	1.00
43_Q	76_A	1.592	1.00
92_C	124_V	1.568	1.00
18_D	51_Q	1.555	1.00
112_A	115_R	1.533	1.00
162_Q	166_A	1.528	1.00
47_K	51_Q	1.512	1.00
177_V	233_I	1.512	1.00
128_C	132_H	1.487	1.00
173_I	190_L	1.486	1.00
107_E	137_T	1.485	1.00
118_A	146_L	1.478	1.00
162_Q	192_L	1.476	1.00
110_F	126_M	1.459	1.00
150_V	255_L	1.444	1.00
231_Q	235_H	1.437	1.00
184_L	188_E	1.424	1.00
2_F	31_G	1.414	1.00
170_Y	197_K	1.413	1.00
78_I	120_L	1.402	1.00
188_E	191_P	1.397	1.00
137_T	141_P	1.389	1.00
161_M	171_I	1.384	1.00
184_L	187_R	1.370	1.00
170_Y	254_T	1.367	1.00
227_P	231_Q	1.366	1.00
157_T	160_E	1.363	1.00
38_N	41_E	1.348	1.00
121_N	148_G	1.344	1.00
24_A	32_L	1.342	1.00
136_M	163_A	1.323	1.00
74_E	112_A	1.299	1.00
110_F	135_F	1.297	1.00
111_V	138_L	1.296	1.00
107_E	111_V	1.295	1.00
2_F	33_L	1.292	1.00
249_D	253_K	1.291	1.00
76_A	79_E	1.284	1.00
81_A	120_L	1.282	1.00
228_H	231_Q	1.276	1.00
9_T	41_E	1.266	1.00
212_L	228_H	1.260	1.00
187_R	236_W	1.257	1.00
243_W	246_A	1.251	1.00
33_L	87_V	1.248	1.00
2_F	249_D	1.244	1.00
45_A	57_S	1.237	1.00
118_A	142_W	1.234	1.00
96_F	107_E	1.234	1.00
99_N	103_P	1.233	1.00
171_I	193_I	1.229	1.00
47_K	50_R	1.220	1.00
194_P	197_K	1.220	1.00
64_H	98_R	1.214	1.00
36_G	42_S	1.207	1.00
212_L	225_H	1.206	1.00
249_D	252_V	1.205	1.00
240_D	243_W	1.204	1.00
6_V	204_A	1.197	1.00
239_E	243_W	1.191	1.00
102_T	105_E	1.189	1.00
230_L	248_T	1.184	1.00
107_E	138_L	1.182	1.00
173_I	198_L	1.180	1.00
233_I	244_L	1.171	1.00
165_V	197_K	1.160	1.00
39_L	42_S	1.147	1.00
70_Q	73_T	1.147	1.00
103_P	107_E	1.146	1.00
34_I	45_A	1.140	1.00
16_D	19_D	1.138	1.00
46_Q	57_S	1.137	1.00
248_T	252_V	1.134	1.00
13_F	220_R	1.128	1.00
199_L	255_L	1.125	1.00
159_E	162_Q	1.114	1.00
39_L	73_T	1.114	1.00
50_R	85_E	1.110	1.00
35_T	125_F	1.096	1.00
232_R	236_W	1.084	1.00
221_N	225_H	1.078	1.00
79_E	82_A	1.075	1.00
133_E	160_E	1.074	1.00
19_D	23_C	1.072	1.00
18_D	22_A	1.066	1.00
64_H	101_S	1.066	1.00
32_L	55_C	1.062	1.00
121_N	147_P	1.059	1.00
190_L	237_R	1.057	1.00
133_E	163_A	1.051	1.00
66_S	109_A	1.050	1.00
200_I	226_L	1.041	1.00
132_H	160_E	1.037	1.00
104_E	108_R	1.035	1.00
212_L	219_R	1.029	1.00
2_F	252_V	1.023	1.00
170_Y	255_L	1.019	1.00
115_R	119_D	1.013	1.00
104_E	107_E	1.013	1.00
43_Q	47_K	1.011	1.00
23_C	224_A	1.008	1.00
78_I	82_A	1.005	1.00
158_R	189_L	0.999	1.00
46_Q	83_Q	0.996	1.00
34_I	55_C	0.993	1.00
19_D	22_A	0.991	1.00
188_E	192_L	0.981	1.00
39_L	76_A	0.977	1.00
105_E	108_R	0.977	1.00
65_D	68_Q	0.975	1.00
44_Q	47_K	0.965	1.00
200_I	233_I	0.964	1.00
156_G	160_E	0.963	1.00
179_D	208_L	0.958	1.00
247_T	250_A	0.955	1.00
46_Q	59_A	0.953	1.00
181_R	210_R	0.951	1.00
158_R	188_E	0.943	1.00
245_A	249_D	0.941	1.00
43_Q	80_L	0.939	1.00
230_L	245_A	0.936	1.00
173_I	193_I	0.936	1.00
49_A	55_C	0.936	1.00
200_I	248_T	0.929	1.00
177_V	190_L	0.927	1.00
149_A	255_L	0.916	1.00
69_W	74_E	0.909	1.00
18_D	52_Y	0.906	1.00
222_E	225_H	0.905	1.00
230_L	244_L	0.902	1.00
243_W	247_T	0.894	1.00
4_I	199_L	0.892	1.00
78_I	116_I	0.892	1.00
244_L	248_T	0.892	1.00
172_G	199_L	0.888	1.00
33_L	252_V	0.888	1.00
46_Q	50_R	0.887	1.00
136_M	164_C	0.886	1.00
8_L	223_P	0.885	1.00
227_P	241_A	0.873	1.00
118_A	143_L	0.871	1.00
150_V	256_F	0.868	1.00
190_L	236_W	0.867	1.00
45_A	49_A	0.865	1.00
237_R	244_L	0.863	1.00
21_V	52_Y	0.853	1.00
195_A	244_L	0.852	1.00
66_S	105_E	0.839	1.00
126_M	151_L	0.838	1.00
75_E	79_E	0.837	1.00
165_V	194_P	0.833	1.00
114_L	118_A	0.830	1.00
69_W	109_A	0.825	1.00
103_P	134_R	0.821	1.00
97_N	130_D	0.821	1.00
59_A	86_V	0.818	1.00
241_A	245_A	0.816	1.00
35_T	58_T	0.812	1.00
99_N	102_T	0.804	1.00
132_H	156_G	0.803	1.00
126_M	135_F	0.802	1.00
128_C	156_G	0.802	1.00
138_L	141_P	0.798	1.00
74_E	78_I	0.795	1.00
86_V	122_M	0.791	1.00
134_R	137_T	0.790	1.00
82_A	120_L	0.786	1.00
136_M	160_E	0.786	1.00
37_T	41_E	0.783	1.00
191_P	236_W	0.782	1.00
4_I	150_V	0.782	1.00
30_N	249_D	0.779	1.00
61_V	69_W	0.776	1.00
165_V	171_I	0.774	1.00
226_L	229_I	0.773	1.00
76_A	80_L	0.772	1.00
23_C	26_D	0.769	1.00
132_H	164_C	0.767	0.99
75_E	78_I	0.764	0.99
230_L	234_A	0.764	0.99
116_I	120_L	0.763	0.99
33_L	58_T	0.754	0.99
170_Y	199_L	0.747	0.99
242_A	246_A	0.745	0.99
21_V	32_L	0.743	0.99
118_A	147_P	0.737	0.99
100_F	103_P	0.735	0.99
73_T	76_A	0.733	0.99
9_T	44_Q	0.731	0.99
250_A	253_K	0.729	0.99
69_W	73_T	0.728	0.99
198_L	244_L	0.728	0.99
89_I	92_C	0.726	0.99
148_G	257_G	0.723	0.99
140_E	166_A	0.714	0.99
64_H	100_F	0.712	0.99
233_I	237_R	0.711	0.99
138_L	142_W	0.703	0.99
176_W	179_D	0.702	0.99
111_V	115_R	0.701	0.99
41_E	45_A	0.700	0.99
191_P	238_G	0.699	0.99
198_L	237_R	0.692	0.99
10_S	206_Y	0.690	0.99
13_F	17_R	0.687	0.99
239_E	247_T	0.685	0.99
27_A	227_P	0.682	0.99
150_V	172_G	0.682	0.99
38_N	68_Q	0.669	0.99
105_E	109_A	0.669	0.99
36_G	45_A	0.666	0.99
56_W	85_E	0.665	0.99
88_A	125_F	0.664	0.99
14_A	44_Q	0.664	0.99
194_P	237_R	0.662	0.99
42_S	80_L	0.661	0.99
176_W	207_L	0.659	0.98
22_A	25_F	0.654	0.98
42_S	77_I	0.653	0.98
114_L	138_L	0.651	0.98
4_I	125_F	0.645	0.98
128_C	164_C	0.644	0.98
247_T	254_T	0.643	0.98
161_M	165_V	0.639	0.98
179_D	211_D	0.638	0.98
10_S	13_F	0.637	0.98
92_C	109_A	0.636	0.98
59_A	80_L	0.636	0.98
161_M	193_I	0.634	0.98
164_C	171_I	0.633	0.98
165_V	193_I	0.633	0.98
21_V	25_F	0.630	0.98
118_A	145_K	0.629	0.98
161_M	189_L	0.628	0.98
193_I	198_L	0.627	0.98
79_E	83_Q	0.626	0.98
143_L	146_L	0.624	0.98
67_S	102_T	0.620	0.98
154_F	160_E	0.620	0.98
114_L	142_W	0.617	0.98
74_E	116_I	0.615	0.98
186_L	189_L	0.614	0.98
136_M	140_E	0.613	0.98
208_L	225_H	0.612	0.98
165_V	192_L	0.611	0.98
184_L	191_P	0.611	0.98
121_N	257_G	0.610	0.97
56_W	87_V	0.608	0.97
42_S	59_A	0.607	0.97
66_S	101_S	0.599	0.97
125_F	256_F	0.595	0.97
24_A	222_E	0.593	0.97
198_L	248_T	0.593	0.97
199_L	252_V	0.593	0.97
178_C	210_R	0.589	0.97
237_R	247_T	0.587	0.97
185_E	188_E	0.586	0.97
17_R	20_V	0.585	0.97
42_S	57_S	0.585	0.97
109_A	113_Q	0.582	0.97
121_N	146_L	0.580	0.97
17_R	220_R	0.580	0.97
20_V	220_R	0.579	0.97
9_T	34_I	0.579	0.97
42_S	45_A	0.578	0.97
132_H	136_M	0.577	0.97
94_L	131_A	0.577	0.97
9_T	37_T	0.575	0.96
151_L	172_G	0.575	0.96
13_F	16_D	0.572	0.96
150_V	199_L	0.572	0.96
71_A	112_A	0.572	0.96
25_F	30_N	0.571	0.96
16_D	20_V	0.570	0.96
176_W	186_L	0.568	0.96
163_A	167_H	0.568	0.96
196_E	254_T	0.567	0.96
27_A	224_A	0.566	0.96
24_A	29_V	0.566	0.96
71_A	108_R	0.565	0.96
81_A	86_V	0.562	0.96
21_V	55_C	0.561	0.96
234_A	241_A	0.560	0.96
2_F	253_K	0.560	0.96
170_Y	251_N	0.559	0.96
24_A	28_G	0.556	0.96
179_D	210_R	0.552	0.96
67_S	101_S	0.549	0.95
143_L	169_I	0.547	0.95
72_A	75_E	0.546	0.95
136_M	167_H	0.545	0.95
67_S	105_E	0.544	0.95
40_R	44_Q	0.543	0.95
40_R	68_Q	0.543	0.95
60_G	113_Q	0.541	0.95
247_T	251_N	0.541	0.95
242_A	245_A	0.541	0.95
196_E	247_T	0.539	0.95
97_N	129_R	0.538	0.95
187_R	191_P	0.537	0.95
174_T	207_L	0.535	0.95
177_V	244_L	0.535	0.95
12_Q	220_R	0.535	0.95
37_T	65_D	0.533	0.95
142_W	146_L	0.531	0.94
24_A	224_A	0.528	0.94
33_L	256_F	0.527	0.94
46_Q	80_L	0.527	0.94
153_C	207_L	0.524	0.94
20_V	23_C	0.522	0.94
225_H	228_H	0.520	0.94
115_R	118_A	0.520	0.94
154_F	164_C	0.519	0.94
48_L	55_C	0.518	0.94
46_Q	49_A	0.516	0.94
112_A	116_I	0.515	0.94
251_N	254_T	0.515	0.94
10_S	37_T	0.511	0.93
176_W	183_G	0.511	0.93
186_L	190_L	0.510	0.93
53_S	85_E	0.509	0.93
132_H	135_F	0.507	0.93
160_E	164_C	0.506	0.93
172_G	207_L	0.504	0.93
183_G	187_R	0.503	0.93
235_H	238_G	0.502	0.93
116_I	119_D	0.500	0.93
94_L	107_E	0.500	0.93
177_V	187_R	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3e2vA	1	0.9692	100	0.193	Contact Map
3ipwA	1	0.9846	100	0.246	Contact Map
1j6oA	1	0.9808	100	0.314	Contact Map
2xioA	1	0.9846	100	0.316	Contact Map
3gg7A	1	0.9231	100	0.349	Contact Map
1xwyA	1	0.9923	100	0.365	Contact Map
3rcmA	1	1	100	0.366	Contact Map
2gzxA	1	0.9692	100	0.382	Contact Map
2y1hA	2	0.9538	100	0.393	Contact Map
1zzmA	1	0.9731	100	0.396	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0094 seconds.