STHA - ECOLI - GREMLIN Contacts

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STHA - Soluble pyridine nucleotide transhydrogenase

UniProt:	P27306	Sequences: MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQGFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTHPRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQEMSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTDSLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALVKGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMNVGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11428
Length:	466 (448)
Sequences:	13711 (8887)
Seq/√Len:	419.9

ECOLI - STHA DLDH GSHR RCLA HCAD NORW
BACSU - DLDH1 DLDH2 DLDH3
HALSA - DLDH Q9HSN0 Q9HP48 Q9HR27
SULSO - Q97VD9 Q97XZ3 Q97Z19 Q97WE3 Q97VQ4 Q97Y24 Q97YT2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
180_L	262_A	4.199	1.00
296_N	300_Q	4.081	1.00
37_R	116_N	3.872	1.00
286_E	294_K	2.933	1.00
410_I	424_G	2.921	1.00
121_D	124_T	2.913	1.00
178_H	201_K	2.875	1.00
7_Y	111_E	2.795	1.00
201_K	233_V	2.783	1.00
203_D	235_R	2.736	1.00
372_P	403_E	2.718	1.00
149_R	276_D	2.660	1.00
6_D	140_E	2.595	1.00
423_I	445_F	2.558	1.00
7_Y	33_A	2.557	1.00
224_S	228_W	2.525	1.00
279_A	282_N	2.508	1.00
372_P	402_R	2.466	1.00
6_D	138_T	2.457	1.00
175_E	200_V	2.429	1.00
21_A	143_V	2.344	1.00
217_Q	364_Q	2.293	1.00
139_A	142_F	2.288	1.00
149_R	274_N	2.282	1.00
151_Y	272_T	2.247	1.00
178_H	263_D	2.239	1.00
33_A	113_L	2.232	1.00
242_K	253_H	2.218	1.00
361_K	366_L	2.205	1.00
124_T	136_T	2.205	1.00
401_H	404_T	2.199	1.00
244_E	253_H	2.171	1.00
374_E	402_R	2.168	1.00
361_K	369_M	2.164	1.00
251_I	259_K	2.144	1.00
10_I	137_L	2.133	1.00
180_L	205_I	2.115	1.00
412_C	417_A	2.103	1.00
126_A	136_T	2.102	1.00
329_A	333_L	2.091	1.00
405_K	438_E	2.075	1.00
288_D	292_Q	2.059	1.00
430_Q	435_N	2.058	1.00
406_E	434_G	2.053	1.00
118_R	126_A	2.033	1.00
156_V	242_K	2.001	1.00
17_G	309_V	1.980	1.00
10_I	35_I	1.973	1.00
189_C	204_L	1.965	1.00
9_A	25_L	1.965	1.00
10_I	125_L	1.945	1.00
75_H	82_S	1.945	1.00
120_V	126_A	1.926	1.00
251_I	261_K	1.900	1.00
241_E	255_K	1.899	1.00
165_D	168_S	1.878	1.00
209_D	237_N	1.865	1.00
239_E	255_K	1.846	1.00
235_R	258_K	1.838	1.00
373_Y	399_L	1.830	1.00
120_V	136_T	1.825	1.00
149_R	272_T	1.821	1.00
427_I	435_N	1.795	1.00
180_L	252_M	1.774	1.00
363_E	397_K	1.770	1.00
244_E	251_I	1.762	1.00
196_R	201_K	1.743	1.00
363_E	367_T	1.741	1.00
253_H	259_K	1.704	1.00
364_Q	368_A	1.696	1.00
128_D	132_G	1.696	1.00
119_F	142_F	1.693	1.00
189_C	352_T	1.682	1.00
12_I	117_A	1.663	1.00
141_K	305_H	1.660	1.00
300_Q	304_P	1.659	1.00
10_I	139_A	1.653	1.00
82_S	85_D	1.644	1.00
355_E	418_A	1.643	1.00
398_I	410_I	1.639	1.00
75_H	80_R	1.630	1.00
143_V	333_L	1.627	1.00
10_I	33_A	1.624	1.00
366_L	373_Y	1.613	1.00
124_T	138_T	1.606	1.00
144_I	312_V	1.598	1.00
179_V	200_V	1.589	1.00
8_D	140_E	1.588	1.00
179_V	195_F	1.577	1.00
210_R	220_S	1.575	1.00
113_L	137_L	1.548	1.00
177_R	201_K	1.546	1.00
246_C	251_I	1.526	1.00
85_D	88_N	1.486	1.00
371_V	408_L	1.484	1.00
218_E	377_R	1.483	1.00
164_Y	264_C	1.478	1.00
163_I	243_I	1.477	1.00
102_Q	114_Q	1.477	1.00
241_E	253_H	1.463	1.00
235_R	238_E	1.461	1.00
164_Y	172_M	1.460	1.00
307_Y	332_A	1.445	1.00
115_G	127_L	1.440	1.00
207_T	239_E	1.423	1.00
366_L	399_L	1.417	1.00
436_T	439_Y	1.416	1.00
177_R	263_D	1.407	1.00
141_K	333_L	1.403	1.00
398_I	458_A	1.391	1.00
9_A	30_A	1.390	1.00
365_Q	368_A	1.387	1.00
300_Q	305_H	1.372	1.00
216_D	397_K	1.366	1.00
7_Y	113_L	1.364	1.00
197_G	230_S	1.362	1.00
222_S	413_F	1.361	1.00
62_R	65_E	1.360	1.00
41_V	112_I	1.359	1.00
254_L	260_L	1.358	1.00
246_C	249_G	1.345	1.00
203_D	233_V	1.337	1.00
35_I	137_L	1.336	1.00
119_F	125_L	1.335	1.00
298_M	332_A	1.335	1.00
146_C	312_V	1.322	1.00
299_Y	313_I	1.316	1.00
143_V	309_V	1.314	1.00
8_D	31_R	1.302	1.00
33_A	137_L	1.297	1.00
249_G	261_K	1.296	1.00
196_R	232_V	1.295	1.00
169_I	195_F	1.294	1.00
91_D	95_N	1.287	1.00
24_G	331_Q	1.286	1.00
372_P	401_H	1.274	1.00
9_A	143_V	1.273	1.00
375_V	399_L	1.271	1.00
184_A	211_L	1.269	1.00
119_F	144_I	1.266	1.00
288_D	294_K	1.243	1.00
75_H	85_D	1.243	1.00
48_W	167_D	1.241	1.00
125_L	129_C	1.240	1.00
225_Y	228_W	1.235	1.00
219_M	413_F	1.216	1.00
204_L	234_I	1.214	1.00
219_M	395_T	1.210	1.00
283_I	303_Q	1.207	1.00
205_I	260_L	1.197	1.00
215_L	348_T	1.194	1.00
210_R	217_Q	1.186	1.00
286_E	302_A	1.186	1.00
123_H	305_H	1.182	1.00
303_Q	306_V	1.181	1.00
223_L	413_F	1.173	1.00
224_S	234_I	1.171	1.00
87_L	91_D	1.167	1.00
206_N	236_H	1.167	1.00
356_I	413_F	1.162	1.00
152_H	165_D	1.160	1.00
238_E	256_S	1.157	1.00
215_L	358_S	1.157	1.00
217_Q	221_D	1.157	1.00
398_I	424_G	1.155	1.00
205_I	254_L	1.152	1.00
380_F	414_G	1.150	1.00
218_E	397_K	1.150	1.00
396_L	453_A	1.147	1.00
157_D	160_H	1.147	1.00
246_C	261_K	1.145	1.00
280_L	285_L	1.144	1.00
12_I	144_I	1.144	1.00
34_V	105_Y	1.140	1.00
162_R	245_G	1.140	1.00
297_S	340_A	1.139	1.00
326_G	330_A	1.139	1.00
122_E	303_Q	1.138	1.00
118_R	279_A	1.130	1.00
113_L	135_E	1.126	1.00
238_E	254_L	1.126	1.00
111_E	135_E	1.124	1.00
31_R	111_E	1.124	1.00
182_Y	265_L	1.123	1.00
401_H	406_E	1.120	1.00
424_G	454_Y	1.116	1.00
293_L	312_V	1.111	1.00
349_G	446_N	1.108	1.00
35_I	117_A	1.099	1.00
430_Q	439_Y	1.091	1.00
422_H	446_N	1.090	1.00
363_E	375_V	1.089	1.00
243_I	250_V	1.088	1.00
365_Q	369_M	1.087	1.00
68_Q	71_L	1.086	1.00
377_R	395_T	1.080	1.00
285_L	293_L	1.065	1.00
226_H	229_N	1.063	1.00
88_N	92_N	1.060	1.00
224_S	236_H	1.057	1.00
164_Y	168_S	1.054	1.00
162_R	250_V	1.053	1.00
23_M	108_N	1.052	1.00
367_T	373_Y	1.051	1.00
210_R	224_S	1.049	1.00
363_E	373_Y	1.049	1.00
160_H	245_G	1.048	1.00
309_V	329_A	1.042	1.00
225_Y	229_N	1.040	1.00
362_T	365_Q	1.039	1.00
116_N	277_S	1.039	1.00
348_T	358_S	1.039	1.00
17_G	322_A	1.037	1.00
245_G	249_G	1.034	1.00
119_F	139_A	1.031	1.00
357_S	421_I	1.029	1.00
162_R	264_C	1.026	1.00
118_R	128_D	1.025	1.00
125_L	305_H	1.021	1.00
164_Y	169_I	1.017	1.00
84_A	173_H	1.016	1.00
58_H	62_R	1.012	1.00
129_C	135_E	1.010	1.00
299_Y	329_A	1.006	1.00
345_D	428_M	1.005	1.00
154_T	158_F	1.004	1.00
357_S	417_A	1.003	1.00
227_F	232_V	1.001	1.00
119_F	282_N	0.999	1.00
228_W	233_V	0.999	1.00
120_V	124_T	0.998	1.00
83_F	87_L	0.997	1.00
371_V	401_H	0.992	1.00
179_V	264_C	0.988	1.00
349_G	418_A	0.987	1.00
178_H	200_V	0.985	1.00
275_T	287_T	0.983	1.00
243_I	265_L	0.983	1.00
366_L	371_V	0.980	1.00
92_N	96_Q	0.976	1.00
223_L	356_I	0.973	1.00
295_V	313_I	0.973	1.00
30_A	334_V	0.972	1.00
342_L	429_E	0.968	1.00
416_R	419_E	0.965	1.00
245_G	248_D	0.965	1.00
45_C	50_T	0.963	1.00
405_K	437_I	0.962	1.00
374_E	405_K	0.959	1.00
7_Y	31_R	0.958	1.00
316_P	346_I	0.958	1.00
179_V	266_L	0.958	1.00
102_Q	106_E	0.957	1.00
35_I	115_G	0.957	1.00
245_G	250_V	0.955	1.00
211_L	234_I	0.953	1.00
283_I	306_V	0.950	1.00
219_M	411_H	0.950	1.00
155_D	158_F	0.947	1.00
189_C	227_F	0.947	1.00
244_E	259_K	0.944	1.00
28_Q	334_V	0.943	1.00
229_N	393_V	0.943	1.00
254_L	258_K	0.942	1.00
118_R	282_N	0.941	1.00
235_R	260_L	0.941	1.00
30_A	140_E	0.940	1.00
210_R	364_Q	0.937	1.00
14_S	34_V	0.936	1.00
359_V	428_M	0.934	1.00
39_Q	48_W	0.934	1.00
28_Q	331_Q	0.932	1.00
14_S	41_V	0.932	1.00
422_H	451_A	0.931	1.00
24_G	28_Q	0.928	1.00
184_A	206_N	0.927	1.00
294_K	302_A	0.922	1.00
371_V	399_L	0.921	1.00
211_L	224_S	0.921	1.00
180_L	260_L	0.915	1.00
222_S	225_Y	0.915	1.00
59_A	86_I	0.915	1.00
63_I	67_N	0.914	1.00
178_H	249_G	0.910	1.00
435_N	439_Y	0.909	1.00
363_E	399_L	0.903	1.00
308_A	312_V	0.901	1.00
119_F	279_A	0.899	1.00
119_F	283_I	0.897	1.00
174_H	264_C	0.897	1.00
47_H	98_T	0.896	1.00
396_L	412_C	0.896	1.00
300_Q	332_A	0.895	1.00
178_H	262_A	0.894	1.00
178_H	203_D	0.892	1.00
277_S	280_L	0.891	1.00
285_L	303_Q	0.890	1.00
205_I	235_R	0.890	1.00
233_V	258_K	0.889	1.00
142_F	306_V	0.888	1.00
30_A	141_K	0.888	1.00
329_A	332_A	0.887	1.00
250_V	265_L	0.885	1.00
219_M	356_I	0.885	1.00
287_T	294_K	0.884	1.00
122_E	305_H	0.884	1.00
330_A	334_V	0.882	1.00
377_R	397_K	0.881	1.00
59_A	89_H	0.881	1.00
64_I	67_N	0.880	1.00
361_K	365_Q	0.879	1.00
64_I	230_S	0.879	1.00
221_D	225_Y	0.876	1.00
182_Y	267_Y	0.871	1.00
178_H	261_K	0.866	1.00
118_R	277_S	0.866	1.00
222_S	226_H	0.860	1.00
60_V	197_G	0.854	1.00
285_L	302_A	0.850	1.00
328_I	332_A	0.850	1.00
70_P	85_D	0.847	1.00
300_Q	307_Y	0.845	1.00
105_Y	110_C	0.845	1.00
141_K	307_Y	0.843	1.00
12_I	278_L	0.842	1.00
20_G	323_Y	0.839	1.00
87_L	90_A	0.838	1.00
188_G	206_N	0.835	1.00
211_L	236_H	0.835	1.00
295_V	308_A	0.834	1.00
299_Y	332_A	0.833	1.00
182_Y	269_N	0.833	1.00
221_D	224_S	0.829	1.00
284_G	303_Q	0.827	1.00
328_I	341_H	0.827	1.00
161_P	245_G	0.827	1.00
64_I	197_G	0.826	1.00
238_E	258_K	0.826	1.00
12_I	125_L	0.824	1.00
186_V	350_I	0.823	1.00
95_N	99_R	0.821	1.00
122_E	284_G	0.819	1.00
273_G	292_Q	0.817	1.00
163_I	267_Y	0.817	1.00
226_H	393_V	0.817	1.00
182_Y	240_Y	0.816	1.00
168_S	171_S	0.816	1.00
151_Y	269_N	0.813	1.00
57_R	194_I	0.812	1.00
105_Y	112_I	0.812	1.00
94_I	97_Q	0.810	1.00
61_S	65_E	0.808	1.00
10_I	142_F	0.808	1.00
9_A	330_A	0.805	1.00
30_A	333_L	0.804	1.00
226_H	230_S	0.803	1.00
103_G	107_R	0.803	1.00
77_R	80_R	0.801	1.00
25_L	330_A	0.801	1.00
435_N	440_F	0.798	1.00
76_S	79_L	0.796	1.00
156_V	160_H	0.796	1.00
423_I	426_A	0.795	1.00
407_I	424_G	0.795	1.00
226_H	413_F	0.794	1.00
64_I	68_Q	0.792	1.00
88_N	173_H	0.792	1.00
427_I	440_F	0.789	1.00
96_Q	387_Q	0.787	1.00
196_R	230_S	0.786	1.00
410_I	428_M	0.785	1.00
362_T	411_H	0.784	1.00
374_E	400_F	0.784	1.00
235_R	254_L	0.784	1.00
90_A	94_I	0.783	1.00
205_I	238_E	0.782	1.00
56_L	87_L	0.781	1.00
208_R	213_A	0.780	1.00
160_H	168_S	0.780	1.00
8_D	30_A	0.779	1.00
156_V	159_T	0.778	1.00
24_G	27_K	0.777	1.00
11_V	18_G	0.773	1.00
210_R	221_D	0.773	1.00
25_L	30_A	0.772	1.00
243_I	252_M	0.770	1.00
203_D	262_A	0.767	1.00
181_I	266_L	0.765	1.00
99_R	102_Q	0.764	1.00
53_S	191_Y	0.763	1.00
292_Q	317_S	0.762	1.00
129_C	132_G	0.762	1.00
24_G	330_A	0.761	1.00
279_A	283_I	0.761	1.00
359_V	425_Q	0.760	1.00
92_N	95_N	0.760	1.00
101_R	105_Y	0.759	1.00
21_A	326_G	0.758	1.00
66_F	76_S	0.757	1.00
36_E	40_N	0.754	1.00
39_Q	114_Q	0.753	1.00
66_F	69_N	0.753	1.00
155_D	159_T	0.752	1.00
331_Q	336_G	0.751	1.00
223_L	352_T	0.751	1.00
276_D	281_Q	0.750	1.00
367_T	370_K	0.750	1.00
424_G	428_M	0.750	1.00
143_V	329_A	0.749	1.00
366_L	408_L	0.746	1.00
379_Q	382_H	0.741	1.00
21_A	330_A	0.739	1.00
188_G	207_T	0.739	1.00
123_H	138_T	0.739	1.00
99_R	103_G	0.738	1.00
227_F	234_I	0.736	1.00
283_I	302_A	0.736	1.00
197_G	353_I	0.736	1.00
398_I	457_A	0.735	1.00
151_Y	154_T	0.735	1.00
376_G	457_A	0.728	1.00
194_I	198_M	0.725	1.00
67_N	78_L	0.724	1.00
207_T	213_A	0.722	1.00
293_L	308_A	0.722	1.00
283_I	287_T	0.721	1.00
193_S	197_G	0.720	1.00
142_F	305_H	0.717	1.00
344_E	369_M	0.716	1.00
401_H	408_L	0.715	1.00
172_M	264_C	0.711	1.00
406_E	436_T	0.710	1.00
429_E	442_N	0.709	1.00
325_Q	343_I	0.708	1.00
84_A	88_N	0.707	1.00
152_H	158_F	0.705	1.00
355_E	416_R	0.704	1.00
215_L	350_I	0.703	1.00
148_S	271_R	0.703	1.00
68_Q	390_G	0.702	1.00
280_L	287_T	0.702	1.00
127_L	137_L	0.701	1.00
209_D	217_Q	0.701	1.00
240_Y	252_M	0.700	1.00
59_A	72_Y	0.700	1.00
321_A	346_I	0.698	1.00
58_H	61_S	0.697	1.00
212_L	223_L	0.697	1.00
128_D	131_D	0.696	1.00
280_L	283_I	0.695	1.00
216_D	411_H	0.694	1.00
7_Y	10_I	0.693	1.00
399_L	402_R	0.692	1.00
21_A	329_A	0.691	1.00
447_Y	452_E	0.691	1.00
146_C	278_L	0.689	1.00
192_A	204_L	0.686	1.00
407_I	428_M	0.686	1.00
66_F	74_D	0.686	1.00
53_S	57_R	0.686	1.00
40_N	48_W	0.682	1.00
123_H	303_Q	0.676	1.00
122_E	283_I	0.675	1.00
275_T	312_V	0.675	1.00
192_A	232_V	0.674	1.00
324_D	327_R	0.671	1.00
66_F	79_L	0.671	1.00
89_H	93_V	0.669	1.00
115_G	131_D	0.666	0.99
404_T	434_G	0.666	0.99
299_Y	328_I	0.665	0.99
181_I	188_G	0.665	0.99
167_D	271_R	0.662	0.99
250_V	264_C	0.662	0.99
81_S	86_I	0.661	0.99
189_C	211_L	0.659	0.99
206_N	213_A	0.658	0.99
152_H	157_D	0.657	0.99
91_D	171_S	0.657	0.99
380_F	453_A	0.656	0.99
158_F	163_I	0.656	0.99
86_I	198_M	0.655	0.99
100_M	104_F	0.655	0.99
90_A	171_S	0.654	0.99
376_G	400_F	0.654	0.99
331_Q	335_K	0.650	0.99
426_A	440_F	0.647	0.99
152_H	267_Y	0.647	0.99
155_D	240_Y	0.644	0.99
419_E	451_A	0.642	0.99
70_P	75_H	0.640	0.99
166_S	271_R	0.640	0.99
437_I	441_V	0.640	0.99
426_A	443_T	0.639	0.99
8_D	33_A	0.638	0.99
439_Y	442_N	0.636	0.99
425_Q	429_E	0.636	0.99
292_Q	314_G	0.636	0.99
103_G	106_E	0.633	0.99
414_G	417_A	0.633	0.99
426_A	435_N	0.631	0.99
426_A	430_Q	0.629	0.99
287_T	293_L	0.629	0.99
412_C	420_I	0.627	0.99
28_Q	336_G	0.626	0.99
410_I	454_Y	0.625	0.99
295_V	299_Y	0.620	0.99
126_A	132_G	0.618	0.99
373_Y	408_L	0.615	0.99
186_V	348_T	0.615	0.99
132_G	135_E	0.615	0.99
298_M	337_E	0.615	0.99
215_L	356_I	0.614	0.99
238_E	255_K	0.614	0.99
219_M	222_S	0.614	0.99
189_C	234_I	0.612	0.99
400_F	437_I	0.612	0.99
321_A	343_I	0.611	0.99
289_S	294_K	0.610	0.99
115_G	125_L	0.609	0.99
69_N	72_Y	0.607	0.99
331_Q	339_T	0.606	0.99
158_F	267_Y	0.606	0.99
115_G	128_D	0.605	0.99
440_F	458_A	0.604	0.99
36_E	112_I	0.603	0.99
222_S	395_T	0.603	0.99
150_P	166_S	0.601	0.99
191_Y	194_I	0.601	0.99
172_M	195_F	0.600	0.99
153_P	158_F	0.600	0.99
361_K	371_V	0.600	0.99
300_Q	303_Q	0.600	0.99
113_L	127_L	0.600	0.99
153_P	267_Y	0.597	0.99
163_I	265_L	0.590	0.99
102_Q	112_I	0.589	0.99
95_N	98_T	0.588	0.99
34_V	110_C	0.588	0.99
400_F	405_K	0.587	0.99
72_Y	89_H	0.586	0.99
84_A	87_L	0.586	0.99
25_L	32_V	0.584	0.99
97_Q	387_Q	0.584	0.99
391_M	415_E	0.584	0.99
301_T	308_A	0.583	0.99
345_D	359_V	0.583	0.99
297_S	339_T	0.582	0.99
386_A	450_M	0.582	0.99
180_L	265_L	0.582	0.99
193_S	230_S	0.581	0.99
285_L	306_V	0.581	0.99
51_I	384_A	0.580	0.99
26_V	110_C	0.580	0.99
358_S	411_H	0.580	0.99
176_P	200_V	0.579	0.99
50_T	54_K	0.579	0.99
88_N	91_D	0.578	0.99
91_D	94_I	0.577	0.99
298_M	340_A	0.575	0.99
131_D	135_E	0.575	0.99
62_R	69_N	0.575	0.99
23_M	27_K	0.574	0.98
87_L	173_H	0.574	0.98
193_S	227_F	0.573	0.98
150_P	153_P	0.573	0.98
309_V	326_G	0.573	0.98
345_D	429_E	0.573	0.98
44_G	166_S	0.572	0.98
85_D	89_H	0.571	0.98
58_H	65_E	0.568	0.98
40_N	98_T	0.567	0.98
58_H	389_V	0.567	0.98
74_D	81_S	0.565	0.98
41_V	105_Y	0.564	0.98
61_S	353_I	0.564	0.98
35_I	127_L	0.562	0.98
89_H	390_G	0.561	0.98
387_Q	392_N	0.561	0.98
376_G	398_I	0.559	0.98
63_I	74_D	0.559	0.98
429_E	443_T	0.559	0.98
314_G	317_S	0.558	0.98
144_I	293_L	0.558	0.98
396_L	457_A	0.558	0.98
420_I	450_M	0.555	0.98
203_D	260_L	0.554	0.98
430_Q	434_G	0.552	0.98
120_V	282_N	0.552	0.98
158_F	165_D	0.551	0.98
154_T	159_T	0.550	0.98
182_Y	205_I	0.550	0.98
307_Y	333_L	0.550	0.98
361_K	409_G	0.549	0.98
373_Y	402_R	0.549	0.98
143_V	330_A	0.549	0.98
455_R	459_L	0.547	0.98
261_K	264_C	0.547	0.98
178_H	196_R	0.547	0.98
119_F	305_H	0.546	0.98
345_D	425_Q	0.546	0.98
188_G	268_A	0.544	0.98
313_I	325_Q	0.544	0.98
230_S	353_I	0.544	0.98
324_D	328_I	0.544	0.98
148_S	317_S	0.543	0.98
166_S	187_I	0.542	0.98
428_M	435_N	0.542	0.98
6_D	31_R	0.542	0.98
11_V	32_V	0.542	0.98
128_D	135_E	0.541	0.98
40_N	47_H	0.540	0.98
423_I	451_A	0.539	0.98
398_I	407_I	0.539	0.98
206_N	240_Y	0.539	0.98
364_Q	367_T	0.539	0.98
101_R	104_F	0.539	0.98
243_I	267_Y	0.538	0.98
100_M	103_G	0.537	0.98
195_F	200_V	0.536	0.98
321_A	325_Q	0.536	0.98
323_Y	455_R	0.536	0.98
122_E	306_V	0.535	0.98
41_V	102_Q	0.534	0.98
205_I	262_A	0.534	0.98
62_R	66_F	0.533	0.98
324_D	455_R	0.532	0.98
27_K	108_N	0.532	0.98
84_A	174_H	0.530	0.97
384_A	388_I	0.529	0.97
116_N	128_D	0.528	0.97
193_S	353_I	0.527	0.97
438_E	442_N	0.526	0.97
60_V	63_I	0.526	0.97
332_A	338_A	0.526	0.97
327_R	331_Q	0.526	0.97
383_L	386_A	0.525	0.97
60_V	198_M	0.525	0.97
417_A	420_I	0.525	0.97
422_H	425_Q	0.524	0.97
200_V	263_D	0.524	0.97
145_A	309_V	0.524	0.97
380_F	450_M	0.522	0.97
277_S	281_Q	0.522	0.97
11_V	22_A	0.521	0.97
26_V	31_R	0.521	0.97
342_L	345_D	0.521	0.97
392_N	415_E	0.519	0.97
273_G	287_T	0.519	0.97
188_G	213_A	0.518	0.97
90_A	93_V	0.517	0.97
53_S	194_I	0.517	0.97
426_A	445_F	0.516	0.97
254_L	259_K	0.516	0.97
58_H	72_Y	0.515	0.97
353_I	391_M	0.513	0.97
121_D	125_L	0.513	0.97
358_S	365_Q	0.512	0.97
207_T	269_N	0.510	0.97
411_H	424_G	0.510	0.97
407_I	410_I	0.509	0.97
141_K	300_Q	0.507	0.97
17_G	145_A	0.507	0.97
410_I	421_I	0.506	0.97
65_E	68_Q	0.506	0.97
355_E	450_M	0.504	0.97
75_H	79_L	0.504	0.97
425_Q	443_T	0.503	0.97
401_H	405_K	0.502	0.97
140_E	305_H	0.502	0.97
285_L	301_T	0.501	0.96
57_R	61_S	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ojtA	2	0.9871	100	0.205	Contact Map
3ladA	2	0.985	100	0.211	Contact Map
1zmdA	4	0.9893	100	0.218	Contact Map
3ic9A	2	0.9785	100	0.221	Contact Map
1xdiA	3	0.9657	100	0.222	Contact Map
3urhA	2	0.9742	100	0.223	Contact Map
2a8xA	2	0.9807	100	0.227	Contact Map
2wpfA	2	0.9871	100	0.228	Contact Map
4jq9A	3	0.9828	100	0.229	Contact Map
3o0hA	2	0.97	100	0.229	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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