GREMLIN Database
OPDA - Oligopeptidase A
UniProt: P27298 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11441
Length: 680 (658)
Sequences: 3308 (2113)
Seq/√Len: 82.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
158_R261_E7.5261.00
151_R268_E6.1551.00
660_K666_E5.5721.00
233_E237_R5.4321.00
277_N280_F4.7481.00
188_A227_D4.5631.00
227_D336_Y4.4441.00
145_P148_K4.1121.00
27_T92_L3.7081.00
186_E228_N3.6681.00
405_G478_M3.6571.00
276_E280_F3.4981.00
530_K534_D3.4801.00
23_V88_Q3.2971.00
34_R99_W3.2891.00
28_K32_D3.2021.00
184_E195_L3.0291.00
380_E392_R3.0171.00
640_Q644_D2.9971.00
379_K397_Y2.9711.00
230_A233_E2.9231.00
641_S645_N2.9021.00
111_R115_D2.8471.00
123_N126_Q2.8411.00
192_E196_A2.7761.00
155_I265_L2.7371.00
653_E661_R2.7271.00
159_L262_I2.6911.00
645_N661_R2.5891.00
644_D648_S2.5521.00
572_K575_E2.5521.00
315_Q345_L2.5331.00
104_E108_K2.4981.00
306_R310_E2.4931.00
169_N255_N2.4341.00
33_C96_Y2.4151.00
15_S385_D2.3791.00
653_E658_L2.3521.00
292_Q296_D2.3141.00
534_D538_A2.3121.00
371_K377_T2.3101.00
653_E657_D2.2821.00
516_A530_K2.2751.00
38_E42_A2.2371.00
267_H271_Q2.2371.00
199_K203_E2.2251.00
151_R154_E2.1981.00
379_K395_E2.1961.00
257_K261_E2.1711.00
32_D62_V2.1111.00
386_V391_V2.1101.00
361_K364_N2.1071.00
180_L211_L2.1071.00
278_Y608_A2.1061.00
23_V27_T2.0751.00
227_D340_K2.0711.00
104_E149_Q2.0361.00
391_V408_Y2.0261.00
162_L258_V2.0131.00
50_E54_Q1.9931.00
380_E394_F1.9841.00
129_A487_V1.9831.00
41_V103_H1.9821.00
275_F284_A1.9791.00
374_Y505_M1.9441.00
18_L21_H1.9431.00
657_D661_R1.9391.00
317_R321_K1.9291.00
95_E157_T1.9151.00
431_R483_E1.9081.00
186_E234_E1.9031.00
317_R328_E1.9021.00
104_E146_K1.8941.00
630_E663_R1.8871.00
461_H510_W1.8821.00
126_Q484_T1.8761.00
455_K523_E1.8691.00
198_A212_L1.8631.00
180_L207_L1.8561.00
158_R161_E1.8521.00
635_N638_T1.8471.00
170_V600_S1.8361.00
138_E143_G1.8281.00
299_T583_L1.8281.00
444_L474_G1.8061.00
322_A344_H1.8041.00
381_R395_E1.7921.00
28_K31_N1.7841.00
13_P16_K1.7841.00
627_R641_S1.7781.00
150_Q154_E1.7691.00
128_K132_N1.7591.00
574_L596_P1.7531.00
361_K520_G1.7481.00
139_L284_A1.7451.00
398_D402_E1.7431.00
631_E635_N1.7271.00
269_L278_Y1.7191.00
53_C110_Y1.7041.00
219_Y223_M1.7001.00
512_P530_K1.6991.00
29_A66_I1.6951.00
280_F291_P1.6811.00
358_P361_K1.6781.00
308_Q311_K1.6691.00
111_R134_L1.6601.00
87_E168_N1.6521.00
314_A318_A1.6231.00
84_E88_Q1.6181.00
425_D428_G1.6171.00
223_M235_M1.6131.00
575_E579_E1.6101.00
289_E654_E1.6031.00
183_D186_E1.5991.00
123_N483_E1.5831.00
627_R631_E1.5801.00
500_L624_A1.5801.00
277_N563_A1.5751.00
146_K150_Q1.5751.00
148_K151_R1.5731.00
368_E517_F1.5681.00
176_G253_W1.5591.00
319_F344_H1.5581.00
393_F406_S1.5561.00
261_E264_A1.5401.00
289_E293_Q1.5351.00
449_N463_E1.5331.00
182_T210_Y1.5260.99
636_R640_Q1.5200.99
54_Q126_Q1.5160.99
424_D443_Y1.5140.99
349_S352_Q1.5080.99
305_A548_I1.5050.99
107_Y111_R1.5040.99
117_D120_A1.4950.99
127_K131_D1.4950.99
212_L235_M1.4910.99
649_R653_E1.4910.99
116_G120_A1.4840.99
52_L109_A1.4820.99
579_E583_L1.4820.99
23_V92_L1.4790.99
163_G262_I1.4710.99
179_K234_E1.4600.99
41_V105_G1.4580.99
57_A486_G1.4580.99
111_R143_G1.4530.99
279_A609_A1.4520.99
341_Q345_L1.4480.99
216_I220_L1.4460.99
376_I479_L1.4420.99
649_R658_L1.4350.99
512_P516_A1.4340.99
107_Y138_E1.4300.99
324_F337_Y1.4300.99
295_L559_F1.4230.99
125_A483_E1.4220.99
399_E636_R1.4170.99
357_F464_V1.4150.99
36_N60_D1.4150.99
26_V66_I1.4120.99
310_E314_A1.4020.99
205_K211_L1.3940.99
318_A322_A1.3910.99
321_K327_D1.3860.99
182_T209_G1.3860.99
309_G549_L1.3830.99
31_N35_E1.3810.99
259_M573_I1.3810.99
632_G635_N1.3710.99
200_A203_E1.3690.99
423_M477_H1.3690.99
282_S286_K1.3680.99
372_R517_F1.3660.99
623_D665_R1.3620.99
296_D300_D1.3530.99
154_E158_R1.3370.99
314_A317_R1.3370.99
320_A327_D1.3280.99
26_V67_F1.3270.99
219_Y235_M1.3260.99
369_V505_M1.3240.99
19_P81_E1.3240.99
626_S674_E1.3210.98
200_A204_A1.3160.98
201_Q211_L1.3120.98
521_H524_T1.3010.98
199_K208_E1.2990.98
111_R138_E1.2840.98
536_M539_A1.2830.98
177_W234_E1.2830.98
431_R481_R1.2770.98
656_M666_E1.2760.98
370_V471_F1.2710.98
359_E412_Y1.2690.98
178_T211_L1.2690.98
239_Y242_R1.2650.98
626_S629_E1.2640.98
184_E210_Y1.2630.98
114_R134_L1.2600.98
151_R155_I1.2590.98
27_T31_N1.2570.98
42_A105_G1.2570.98
390_D450_R1.2560.98
290_N293_Q1.2520.98
374_Y642_F1.2520.98
259_M596_P1.2520.98
17_I21_H1.2480.98
574_L578_A1.2470.98
180_L209_G1.2460.98
114_R117_D1.2390.98
191_P225_Y1.2320.98
134_L138_E1.2270.98
21_H25_A1.2270.98
80_P84_E1.2200.97
403_L439_K1.2140.97
72_H443_Y1.2080.97
107_Y134_L1.2050.97
531_E534_D1.2020.97
341_Q542_Y1.2010.97
152_Y156_A1.2000.97
368_E372_R1.1970.97
359_E459_F1.1930.97
293_Q296_D1.1910.97
642_F647_L1.1910.97
656_M660_K1.1890.97
625_F633_I1.1840.97
631_E638_T1.1830.97
295_L563_A1.1800.97
481_R648_S1.1800.97
561_L596_P1.1710.97
99_W153_G1.1710.97
40_V52_L1.1690.97
182_T208_E1.1670.97
198_A218_S1.1640.97
85_A89_T1.1620.97
657_D660_K1.1600.97
295_L299_T1.1580.97
203_E207_L1.1580.97
397_Y403_L1.1580.97
615_L676_Y1.1570.96
222_V235_M1.1540.96
173_A243_A1.1540.96
156_A269_L1.1540.96
494_P655_P1.1530.96
313_L329_L1.1490.96
280_F292_Q1.1490.96
77_K416_N1.1490.96
403_L406_S1.1450.96
23_V89_T1.1430.96
368_E371_K1.1380.96
229_Q330_Q1.1380.96
146_K149_Q1.1340.96
22_V73_L1.1340.96
181_V231_L1.1290.96
550_R554_F1.1240.96
136_D486_G1.1220.96
451_P457_A1.1180.96
398_D404_R1.1150.96
165_Q169_N1.1150.96
338_S543_Q1.1140.96
9_F403_L1.1130.96
283_L294_V1.1030.95
161_E165_Q1.1000.95
299_T556_L1.0990.95
139_L281_K1.0990.95
33_C59_V1.0910.95
212_L218_S1.0910.95
318_A321_K1.0880.95
378_A396_L1.0860.95
320_A329_L1.0830.95
377_T397_Y1.0830.95
487_V651_G1.0790.95
108_K112_D1.0780.95
112_D116_G1.0760.95
74_N82_L1.0740.95
386_V393_F1.0730.95
169_N253_W1.0720.95
313_L317_R1.0650.94
430_M438_Q1.0620.94
579_E582_K1.0590.94
659_F663_R1.0590.94
129_A484_T1.0570.94
35_E39_R1.0570.94
256_S597_H1.0530.94
504_F642_F1.0530.94
150_Q153_G1.0530.94
260_E264_A1.0520.94
26_V89_T1.0450.94
442_A477_H1.0430.94
456_P522_Y1.0420.94
190_M198_A1.0420.94
294_V559_F1.0410.94
133_A486_G1.0400.94
74_N86_Y1.0400.94
362_A464_V1.0370.94
219_Y239_Y1.0360.94
48_T55_P1.0350.94
336_Y340_K1.0340.94
398_D643_L1.0320.93
76_V445_T1.0280.93
258_V262_I1.0270.93
560_R580_I1.0270.93
323_E344_H1.0210.93
264_A268_E1.0210.93
38_E103_H1.0190.93
364_N368_E1.0170.93
426_C443_Y1.0150.93
359_E411_L1.0150.93
36_N40_V1.0140.93
339_E342_K1.0120.93
38_E105_G1.0120.93
27_T30_L1.0100.93
511_E625_F1.0090.93
387_W391_V1.0080.93
329_L337_Y1.0070.93
142_I149_Q1.0070.93
656_M667_P1.0040.92
560_R583_L1.0040.92
363_V392_R1.0030.92
169_N258_V1.0010.92
201_Q205_K0.9990.92
348_I536_M0.9970.92
98_T156_A0.9940.92
222_V226_C0.9940.92
520_G525_G0.9930.92
9_F13_P0.9920.92
108_K111_R0.9920.92
116_G119_Y0.9900.92
107_Y143_G0.9860.92
177_W235_M0.9850.92
184_E192_E0.9820.92
427_V441_V0.9810.92
125_A487_V0.9790.92
507_N621_A0.9750.91
395_E403_L0.9710.91
19_P79_S0.9700.91
645_N653_E0.9690.91
511_E629_E0.9650.91
618_D621_A0.9630.91
637_E641_S0.9620.91
73_L77_K0.9610.91
528_L533_L0.9590.91
548_I615_L0.9580.91
425_D491_S0.9560.91
306_R549_L0.9550.90
205_K415_E0.9530.90
343_Q347_S0.9530.90
19_P85_A0.9510.90
668_Q671_A0.9490.90
575_E578_A0.9470.90
34_R38_E0.9440.90
386_V408_Y0.9440.90
621_A675_H0.9420.90
152_Y269_L0.9400.90
35_E38_E0.9390.90
126_Q483_E0.9390.90
363_V409_L0.9390.90
560_R564_E0.9360.90
179_K182_T0.9360.90
184_E199_K0.9350.90
512_P533_L0.9330.89
257_K260_E0.9320.89
87_E165_Q0.9310.89
155_I159_L0.9310.89
20_E81_E0.9280.89
291_P559_F0.9280.89
180_L208_E0.9260.89
530_K533_L0.9250.89
181_V212_L0.9240.89
233_E330_Q0.9220.89
101_G136_D0.9220.89
544_A676_Y0.9200.89
124_T653_E0.9170.89
428_G491_S0.9100.88
323_E337_Y0.9090.88
11_L408_Y0.9080.88
421_A498_V0.9070.88
487_V652_S0.9030.88
47_Y109_A0.9030.88
49_W126_Q0.9010.88
352_Q355_P0.8990.88
494_P654_E0.8980.88
181_V210_Y0.8970.88
119_Y127_K0.8960.87
127_K130_V0.8960.87
288_A294_V0.8950.87
119_Y131_D0.8950.87
295_L560_R0.8920.87
266_R562_H0.8900.87
38_E41_V0.8900.87
458_L522_Y0.8890.87
300_D304_R0.8880.87
448_F459_F0.8850.87
157_T161_E0.8840.87
37_V56_L0.8830.87
21_H24_P0.8810.87
37_V100_V0.8750.86
330_Q588_P0.8750.86
553_E581_K0.8720.86
376_I404_R0.8720.86
119_Y130_V0.8710.86
27_T88_Q0.8690.86
323_E340_K0.8680.86
29_A62_V0.8680.86
421_A466_T0.8680.86
510_W536_M0.8670.86
244_S256_S0.8650.86
147_E150_Q0.8640.85
397_Y401_N0.8630.85
58_E433_A0.8620.85
277_N291_P0.8610.85
27_T89_T0.8600.85
83_R172_D0.8600.85
454_G523_E0.8590.85
658_L661_R0.8550.85
262_I603_F0.8550.85
81_E84_E0.8550.85
48_T51_N0.8550.85
578_A582_K0.8540.85
155_I269_L0.8540.85
47_Y112_D0.8520.85
372_R513_E0.8520.85
113_L130_V0.8510.85
190_M226_C0.8500.85
280_F284_A0.8500.85
236_Y331_P0.8480.84
198_A222_V0.8470.84
260_E573_I0.8470.84
516_A527_P0.8460.84
366_L467_L0.8440.84
645_N649_R0.8440.84
462_D465_I0.8400.84
295_L556_L0.8400.84
340_K343_Q0.8390.84
216_I239_Y0.8390.84
222_V231_L0.8350.83
529_P532_L0.8350.83
139_L275_F0.8350.83
192_E195_L0.8330.83
135_R285_T0.8320.83
267_H566_R0.8300.83
117_D127_K0.8290.83
167_S600_S0.8290.83
47_Y113_L0.8270.83
477_H490_I0.8270.83
622_A675_H0.8270.83
19_P82_L0.8250.83
371_K376_I0.8250.83
356_Y532_L0.8240.83
582_K588_P0.8230.83
26_V30_L0.8230.83
236_Y591_S0.8230.83
645_N658_L0.8220.83
121_T127_K0.8200.82
53_C130_V0.8180.82
313_L587_V0.8160.82
300_D669_L0.8150.82
504_F508_W0.8140.82
515_L533_L0.8130.82
548_I676_Y0.8130.82
307_P310_E0.8130.82
201_Q204_A0.8110.82
630_E665_R0.8110.82
188_A228_N0.8100.82
344_H347_S0.8070.81
294_V298_L0.8070.81
175_M215_D0.8060.81
407_F478_M0.8040.81
375_G399_E0.8040.81
229_Q332_W0.8020.81
623_D663_R0.8010.81
301_L552_L0.8000.81
114_R131_D0.8000.81
363_V467_L0.8000.81
123_N484_T0.7990.81
607_Y614_Y0.7980.81
40_V59_V0.7980.81
23_V85_A0.7980.81
105_G108_K0.7970.81
320_A325_G0.7950.80
395_E406_S0.7950.80
504_F624_A0.7950.80
236_Y240_S0.7950.80
79_S416_N0.7930.80
551_Q615_L0.7920.80
183_D210_Y0.7920.80
135_R284_A0.7920.80
507_N625_F0.7920.80
88_Q92_L0.7910.80
378_A407_F0.7910.80
516_A533_L0.7900.80
18_L24_P0.7870.80
263_L561_L0.7870.80
469_H499_E0.7860.80
226_C231_L0.7860.80
128_K651_G0.7850.80
74_N78_N0.7850.80
11_L406_S0.7830.79
659_F667_P0.7830.79
52_L55_P0.7800.79
343_Q349_S0.7800.79
54_Q58_E0.7800.79
155_I268_E0.7800.79
369_V514_A0.7800.79
175_M416_N0.7780.79
346_Y539_A0.7780.79
308_Q678_I0.7750.79
276_E292_Q0.7750.79
102_Q153_G0.7720.78
571_A579_E0.7720.78
601_H611_Y0.7710.78
165_Q168_N0.7710.78
507_N675_H0.7700.78
319_F341_Q0.7690.78
233_E332_W0.7690.78
22_V70_V0.7690.78
311_K314_A0.7680.78
556_L584_V0.7670.78
643_L648_S0.7660.78
313_L334_I0.7650.78
544_A548_I0.7640.78
407_F444_L0.7620.78
670_D674_E0.7600.77
58_E432_K0.7570.77
186_E230_A0.7570.77
637_E644_D0.7560.77
228_N234_E0.7560.77
387_W426_C0.7550.77
203_E453_N0.7540.77
260_E570_G0.7540.77
207_L211_L0.7530.77
269_L281_K0.7520.77
381_R384_V0.7510.76
199_K209_G0.7510.76
654_E657_D0.7500.76
347_S535_K0.7500.76
158_R257_K0.7500.76
423_M442_A0.7480.76
49_W53_C0.7470.76
371_K378_A0.7460.76
627_R632_G0.7430.76
89_T92_L0.7430.76
120_A130_V0.7410.76
627_R630_E0.7410.76
128_K131_D0.7410.76
165_Q258_V0.7400.75
190_M222_V0.7400.75
34_R96_Y0.7400.75
352_Q532_L0.7370.75
511_E633_I0.7360.75
67_F71_S0.7360.75
458_L521_H0.7350.75
665_R668_Q0.7340.75
36_N59_V0.7330.75
22_V82_L0.7330.75
357_F461_H0.7320.75
188_A336_Y0.7320.75
32_D35_E0.7320.75
431_R437_L0.7310.75
370_V378_A0.7290.74
370_V396_L0.7290.74
321_K325_G0.7290.74
470_E473_H0.7280.74
190_M194_A0.7280.74
191_P194_A0.7280.74
61_D430_M0.7270.74
193_S351_E0.7260.74
271_Q566_R0.7250.74
520_G527_P0.7250.74
317_R329_L0.7250.74
341_Q346_Y0.7240.74
296_D299_T0.7230.74
528_L532_L0.7220.74
202_A211_L0.7220.74
360_N392_R0.7210.74
154_E157_T0.7200.73
77_K82_L0.7200.73
370_V475_L0.7190.73
308_Q545_A0.7190.73
649_R652_S0.7170.73
627_R635_N0.7170.73
601_H614_Y0.7160.73
460_T463_E0.7150.73
113_L120_A0.7140.73
489_G498_V0.7130.73
57_A485_A0.7120.73
40_V55_P0.7120.73
627_R663_R0.7110.72
271_Q276_E0.7090.72
519_S528_L0.7070.72
76_V387_W0.7060.72
159_L265_L0.7060.72
560_R579_E0.7060.72
599_F611_Y0.7050.72
117_D131_D0.7050.72
375_G398_D0.7050.72
404_R478_M0.7040.72
58_E430_M0.7040.72
104_E145_P0.7040.72
310_E317_R0.7020.72
321_K328_E0.7010.71
531_E535_K0.7010.71
384_V393_F0.7000.71
380_E383_D0.7000.71
194_A222_V0.6970.71
229_Q333_D0.6970.71
182_T186_E0.6970.71
132_N135_R0.6970.71
133_A136_D0.6960.71
329_L334_I0.6960.71
311_K315_Q0.6950.71
72_H426_C0.6930.71
34_R92_L0.6930.71
644_D649_R0.6920.70
442_A490_I0.6910.70
551_Q554_F0.6890.70
267_H564_E0.6880.70
148_K271_Q0.6850.70
312_E543_Q0.6850.70
552_L615_L0.6840.70
469_H473_H0.6820.69
161_E261_E0.6810.69
78_N416_N0.6810.69
394_F409_L0.6800.69
552_L556_L0.6800.69
131_D135_R0.6800.69
14_F17_I0.6800.69
49_W55_P0.6790.69
342_K542_Y0.6790.69
72_H76_V0.6780.69
79_S82_L0.6780.69
381_R393_F0.6770.69
149_Q653_E0.6750.69
427_V438_Q0.6750.69
600_S604_A0.6730.68
411_L467_L0.6730.68
412_Y451_P0.6720.68
220_L335_A0.6710.68
507_N622_A0.6710.68
546_L549_L0.6680.68
78_N83_R0.6670.68
377_T401_N0.6660.68
412_Y457_A0.6660.68
482_I652_S0.6660.68
128_K654_E0.6640.67
557_F577_L0.6640.67
90_L94_S0.6600.67
187_L195_L0.6590.67
331_P590_P0.6590.67
92_L95_E0.6570.66
61_D65_R0.6570.66
95_E99_W0.6560.66
631_E641_S0.6560.66
469_H614_Y0.6560.66
315_Q341_Q0.6550.66
37_V103_H0.6540.66
197_A450_R0.6530.66
298_L556_L0.6530.66
619_V667_P0.6530.66
267_H565_F0.6520.66
283_L288_A0.6510.66
26_V85_A0.6510.66
476_H501_P0.6510.66
490_I498_V0.6510.66
278_Y282_S0.6510.66
316_L329_L0.6490.66
381_R406_S0.6470.65
17_I25_A0.6460.65
110_Y133_A0.6460.65
30_L93_L0.6440.65
599_F602_I0.6440.65
409_L444_L0.6430.65
317_R327_D0.6420.65
470_E506_E0.6420.65
319_F323_E0.6410.65
304_R669_L0.6410.65
534_D537_L0.6400.64
71_S93_L0.6380.64
275_F281_K0.6380.64
448_F457_A0.6370.64
224_T545_A0.6360.64
560_R576_T0.6360.64
557_F561_L0.6350.64
55_P130_V0.6350.64
107_Y114_R0.6350.64
33_C100_V0.6340.64
84_E87_E0.6330.64
637_E640_Q0.6320.63
358_P520_G0.6300.63
30_L33_C0.6300.63
306_R583_L0.6300.63
581_K593_G0.6300.63
178_T205_K0.6290.63
424_D445_T0.6280.63
508_W634_F0.6270.63
470_E499_E0.6270.63
577_L595_F0.6260.63
357_F528_L0.6260.63
30_L96_Y0.6250.63
324_F327_D0.6240.62
236_Y332_W0.6200.62
124_T127_K0.6200.62
255_N258_V0.6200.62
549_L552_L0.6200.62
303_K310_E0.6200.62
190_M212_L0.6200.62
36_N39_R0.6190.62
181_V222_V0.6190.62
260_E571_A0.6190.62
88_Q91_P0.6180.62
30_L34_R0.6170.62
114_R127_K0.6170.62
473_H499_E0.6170.62
179_K222_V0.6170.62
495_W613_S0.6160.61
181_V228_N0.6140.61
369_V468_F0.6140.61
631_E637_E0.6140.61
625_F646_I0.6130.61
561_L576_T0.6130.61
72_H424_D0.6120.61
566_R569_Q0.6120.61
29_A33_C0.6110.61
57_A60_D0.6110.61
469_H506_E0.6100.61
428_G488_S0.6100.61
508_W633_I0.6100.61
600_S613_S0.6070.60
44_G51_N0.6070.60
561_L602_I0.6060.60
319_F543_Q0.6060.60
106_L137_F0.6050.60
118_H127_K0.6050.60
417_K502_S0.6040.60
31_N34_R0.6040.60
627_R638_T0.6040.60
580_I584_V0.6030.60
271_Q277_N0.6020.60
481_R644_D0.6020.60
633_I638_T0.6000.59
72_H387_W0.5990.59
47_Y52_L0.5980.59
387_W445_T0.5980.59
291_P563_A0.5970.59
199_K202_A0.5970.59
532_L536_M0.5970.59
466_T601_H0.5970.59
321_K326_V0.5950.59
280_F563_A0.5950.59
286_K617_A0.5950.59
172_D253_W0.5940.59
75_S424_D0.5930.59
188_A340_K0.5920.58
406_S439_K0.5920.58
299_T303_K0.5920.58
66_I93_L0.5920.58
302_A584_V0.5920.58
235_M239_Y0.5910.58
154_E268_E0.5910.58
418_R422_W0.5910.58
546_L550_R0.5910.58
117_D121_T0.5900.58
624_A659_F0.5900.58
139_L285_T0.5890.58
46_P116_G0.5880.58
423_M489_G0.5880.58
256_S573_I0.5870.58
204_A415_E0.5870.58
18_L81_E0.5860.58
99_W103_H0.5850.58
473_H506_E0.5840.57
607_Y611_Y0.5830.57
323_E336_Y0.5820.57
194_A221_P0.5820.57
500_L505_M0.5810.57
599_F607_Y0.5810.57
355_P522_Y0.5800.57
97_S101_G0.5800.57
69_P73_L0.5790.57
307_P311_K0.5780.57
78_N86_Y0.5780.57
499_E502_S0.5780.57
231_L234_E0.5780.57
56_L133_A0.5780.57
548_I555_G0.5770.57
395_E405_G0.5770.57
24_P35_E0.5770.57
409_L474_G0.5760.56
416_N559_F0.5760.56
11_L441_V0.5760.56
335_A338_S0.5760.56
508_W625_F0.5760.56
30_L92_L0.5750.56
230_A234_E0.5750.56
282_S608_A0.5750.56
328_E588_P0.5750.56
601_H607_Y0.5740.56
377_T398_D0.5740.56
64_G425_D0.5730.56
500_L504_F0.5730.56
86_Y164_N0.5720.56
414_R417_K0.5720.56
364_N371_K0.5710.56
499_E614_Y0.5710.56
465_I509_C0.5710.56
138_E284_A0.5710.56
64_G428_G0.5710.56
145_P149_Q0.5710.56
320_A324_F0.5700.56
312_E545_A0.5690.56
174_T419_G0.5690.56
74_N83_R0.5690.56
615_L624_A0.5690.56
33_C36_N0.5680.55
372_R634_F0.5680.55
425_D488_S0.5680.55
355_P523_E0.5670.55
96_Y99_W0.5670.55
316_L341_Q0.5650.55
189_G226_C0.5650.55
363_V378_A0.5650.55
641_S661_R0.5640.55
423_M490_I0.5640.55
54_Q129_A0.5640.55
132_N486_G0.5640.55
299_T560_R0.5630.55
499_E506_E0.5630.55
377_T399_E0.5620.55
288_A616_W0.5620.55
654_E658_L0.5620.55
537_L540_K0.5620.55
476_H493_V0.5620.55
305_A549_L0.5610.54
570_G575_E0.5610.54
120_A127_K0.5610.54
353_L532_L0.5610.54
623_D659_F0.5610.54
303_K307_P0.5610.54
346_Y535_K0.5600.54
557_F576_T0.5600.54
25_A66_I0.5600.54
495_W498_V0.5590.54
10_E13_P0.5590.54
301_L669_L0.5590.54
298_L552_L0.5580.54
50_E118_H0.5560.54
29_A59_V0.5550.54
264_A569_Q0.5550.54
423_M498_V0.5550.54
262_I608_A0.5550.54
8_P65_R0.5540.54
8_P13_P0.5540.54
158_R265_L0.5540.54
287_M500_L0.5530.53
24_P27_T0.5520.53
225_Y239_Y0.5520.53
482_I488_S0.5510.53
642_F646_I0.5510.53
312_E316_L0.5500.53
10_E427_V0.5490.53
611_Y614_Y0.5490.53
293_Q297_F0.5490.53
298_L555_G0.5480.53
665_R671_A0.5480.53
621_A674_E0.5460.52
428_G485_A0.5460.52
205_K213_T0.5450.52
634_F639_G0.5450.52
533_L537_L0.5450.52
185_A195_L0.5450.52
268_E271_Q0.5450.52
405_G439_K0.5440.52
21_H66_I0.5440.52
407_F474_G0.5440.52
110_Y134_L0.5430.52
263_L564_E0.5410.52
448_F467_L0.5400.52
17_I69_P0.5400.52
221_P224_T0.5400.52
602_I608_A0.5400.52
44_G52_L0.5390.52
620_L659_F0.5390.52
544_A547_F0.5380.51
51_N109_A0.5380.51
360_N364_N0.5370.51
33_C40_V0.5370.51
33_C37_V0.5360.51
259_M263_L0.5350.51
183_D228_N0.5350.51
98_T153_G0.5350.51
186_E222_V0.5350.51
43_Q47_Y0.5350.51
317_R320_A0.5340.51
300_D303_K0.5340.51
162_L261_E0.5340.51
622_A672_M0.5340.51
402_E481_R0.5340.51
404_R643_L0.5330.51
548_I672_M0.5310.51
276_E565_F0.5310.51
174_T242_R0.5310.51
179_K235_M0.5300.50
260_E569_Q0.5300.50
49_W484_T0.5300.50
384_V387_W0.5300.50
502_S601_H0.5300.50
203_E206_E0.5290.50
489_G650_G0.5290.50
369_V634_F0.5290.50
37_V41_V0.5290.50
219_Y255_N0.5280.50
342_K350_D0.5280.50
413_A420_G0.5270.50
364_N520_G0.5260.50
526_E531_E0.5250.50
354_R460_T0.5250.50
559_F678_I0.5240.50
200_A450_R0.5240.50
70_V85_A0.5240.50
152_Y273_L0.5230.49
561_L573_I0.5230.49
225_Y343_Q0.5230.49
557_F596_P0.5220.49
363_V366_L0.5220.49
430_M485_A0.5220.49
115_D531_E0.5210.49
326_V337_Y0.5210.49
305_A648_S0.5210.49
185_A389_P0.5200.49
309_G651_G0.5200.49
199_K206_E0.5200.49
643_L647_L0.5190.49
58_E485_A0.5190.49
302_A549_L0.5190.49
511_E634_F0.5180.49
318_A344_H0.5180.49
197_A201_Q0.5170.49
468_F514_A0.5170.49
543_Q546_L0.5170.49
61_D64_G0.5170.49
309_G586_V0.5170.49
229_Q233_E0.5160.49
469_H502_S0.5160.49
470_E614_Y0.5150.48
397_Y439_K0.5150.48
315_Q318_A0.5150.48
127_K276_E0.5150.48
514_A517_F0.5150.48
17_I24_P0.5140.48
508_W628_F0.5140.48
68_S485_A0.5140.48
202_A254_D0.5130.48
85_A88_Q0.5130.48
75_S418_R0.5130.48
45_A48_T0.5130.48
201_Q213_T0.5110.48
16_K385_D0.5110.48
296_D389_P0.5100.48
578_A588_P0.5100.48
132_N487_V0.5100.48
374_Y647_L0.5090.48
42_A148_K0.5080.47
167_S604_A0.5080.47
447_N464_V0.5070.47
346_Y536_M0.5070.47
20_E323_E0.5070.47
339_E347_S0.5070.47
60_D100_V0.5070.47
548_I551_Q0.5070.47
341_Q344_H0.5060.47
88_Q318_A0.5060.47
30_L103_H0.5060.47
198_A201_Q0.5040.47
490_I495_W0.5030.47
495_W617_A0.5030.47
115_D186_E0.5030.47
418_R613_S0.5030.47
532_L535_K0.5030.47
229_Q320_A0.5020.47
286_K495_W0.5020.47
113_L116_G0.5020.47
541_N544_A0.5020.47
411_L445_T0.5010.47
178_T207_L0.5000.46
353_L528_L0.5000.46
185_A188_A0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ka7A 1 0.9882 100 0.205 Contact Map
2o3eA 1 0.9632 100 0.211 Contact Map
1y791 1 0.9882 100 0.222 Contact Map
2o36A 1 0.9485 100 0.256 Contact Map
1r42A 1 0.7765 100 0.58 Contact Map
4ca6A 1 0.7897 100 0.587 Contact Map
4c2oA 1 0.7632 100 0.601 Contact Map
3sksA 1 0.7691 100 0.604 Contact Map
3ahnA 1 0.7882 100 0.614 Contact Map
2qr4A 2 0.7221 100 0.618 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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