OPDA - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

OPDA - Oligopeptidase A

UniProt:	P27298	Sequences: MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQGAPYTWENLCQPLAEVDDVLGRIFSPVSHLNSVKNSPELREAYEQTLPLLSEYSTWVGQHEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLSELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPSYLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFENYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVDELQPWDIAYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDVDVWHPDVRFFELYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNRPVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENWCWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFRPDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADAFSRFEEEGIFNRETGQSFLDNILSRGGSEEPMDLFKRFRGREPQLDAMLEHYGIKG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11441
Length:	680 (658)
Sequences:	3308 (2113)
Seq/√Len:	82.4

ECOLI - OPDA DCP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
158_R	261_E	7.526	1.00
151_R	268_E	6.155	1.00
660_K	666_E	5.572	1.00
233_E	237_R	5.432	1.00
277_N	280_F	4.748	1.00
188_A	227_D	4.563	1.00
227_D	336_Y	4.444	1.00
145_P	148_K	4.112	1.00
27_T	92_L	3.708	1.00
186_E	228_N	3.668	1.00
405_G	478_M	3.657	1.00
276_E	280_F	3.498	1.00
530_K	534_D	3.480	1.00
23_V	88_Q	3.297	1.00
34_R	99_W	3.289	1.00
28_K	32_D	3.202	1.00
184_E	195_L	3.029	1.00
380_E	392_R	3.017	1.00
640_Q	644_D	2.997	1.00
379_K	397_Y	2.971	1.00
230_A	233_E	2.923	1.00
641_S	645_N	2.902	1.00
111_R	115_D	2.847	1.00
123_N	126_Q	2.841	1.00
192_E	196_A	2.776	1.00
155_I	265_L	2.737	1.00
653_E	661_R	2.727	1.00
159_L	262_I	2.691	1.00
645_N	661_R	2.589	1.00
644_D	648_S	2.552	1.00
572_K	575_E	2.552	1.00
315_Q	345_L	2.533	1.00
104_E	108_K	2.498	1.00
306_R	310_E	2.493	1.00
169_N	255_N	2.434	1.00
33_C	96_Y	2.415	1.00
15_S	385_D	2.379	1.00
653_E	658_L	2.352	1.00
292_Q	296_D	2.314	1.00
534_D	538_A	2.312	1.00
371_K	377_T	2.310	1.00
653_E	657_D	2.282	1.00
516_A	530_K	2.275	1.00
38_E	42_A	2.237	1.00
267_H	271_Q	2.237	1.00
199_K	203_E	2.225	1.00
151_R	154_E	2.198	1.00
379_K	395_E	2.196	1.00
257_K	261_E	2.171	1.00
32_D	62_V	2.111	1.00
386_V	391_V	2.110	1.00
361_K	364_N	2.107	1.00
180_L	211_L	2.107	1.00
278_Y	608_A	2.106	1.00
23_V	27_T	2.075	1.00
227_D	340_K	2.071	1.00
104_E	149_Q	2.036	1.00
391_V	408_Y	2.026	1.00
162_L	258_V	2.013	1.00
50_E	54_Q	1.993	1.00
380_E	394_F	1.984	1.00
129_A	487_V	1.983	1.00
41_V	103_H	1.982	1.00
275_F	284_A	1.979	1.00
374_Y	505_M	1.944	1.00
18_L	21_H	1.943	1.00
657_D	661_R	1.939	1.00
317_R	321_K	1.929	1.00
95_E	157_T	1.915	1.00
431_R	483_E	1.908	1.00
186_E	234_E	1.903	1.00
317_R	328_E	1.902	1.00
104_E	146_K	1.894	1.00
630_E	663_R	1.887	1.00
461_H	510_W	1.882	1.00
126_Q	484_T	1.876	1.00
455_K	523_E	1.869	1.00
198_A	212_L	1.863	1.00
180_L	207_L	1.856	1.00
158_R	161_E	1.852	1.00
635_N	638_T	1.847	1.00
170_V	600_S	1.836	1.00
138_E	143_G	1.828	1.00
299_T	583_L	1.828	1.00
444_L	474_G	1.806	1.00
322_A	344_H	1.804	1.00
381_R	395_E	1.792	1.00
28_K	31_N	1.784	1.00
13_P	16_K	1.784	1.00
627_R	641_S	1.778	1.00
150_Q	154_E	1.769	1.00
128_K	132_N	1.759	1.00
574_L	596_P	1.753	1.00
361_K	520_G	1.748	1.00
139_L	284_A	1.745	1.00
398_D	402_E	1.743	1.00
631_E	635_N	1.727	1.00
269_L	278_Y	1.719	1.00
53_C	110_Y	1.704	1.00
219_Y	223_M	1.700	1.00
512_P	530_K	1.699	1.00
29_A	66_I	1.695	1.00
280_F	291_P	1.681	1.00
358_P	361_K	1.678	1.00
308_Q	311_K	1.669	1.00
111_R	134_L	1.660	1.00
87_E	168_N	1.652	1.00
314_A	318_A	1.623	1.00
84_E	88_Q	1.618	1.00
425_D	428_G	1.617	1.00
223_M	235_M	1.613	1.00
575_E	579_E	1.610	1.00
289_E	654_E	1.603	1.00
183_D	186_E	1.599	1.00
123_N	483_E	1.583	1.00
627_R	631_E	1.580	1.00
500_L	624_A	1.580	1.00
277_N	563_A	1.575	1.00
146_K	150_Q	1.575	1.00
148_K	151_R	1.573	1.00
368_E	517_F	1.568	1.00
176_G	253_W	1.559	1.00
319_F	344_H	1.558	1.00
393_F	406_S	1.556	1.00
261_E	264_A	1.540	1.00
289_E	293_Q	1.535	1.00
449_N	463_E	1.533	1.00
182_T	210_Y	1.526	0.99
636_R	640_Q	1.520	0.99
54_Q	126_Q	1.516	0.99
424_D	443_Y	1.514	0.99
349_S	352_Q	1.508	0.99
305_A	548_I	1.505	0.99
107_Y	111_R	1.504	0.99
117_D	120_A	1.495	0.99
127_K	131_D	1.495	0.99
212_L	235_M	1.491	0.99
649_R	653_E	1.491	0.99
116_G	120_A	1.484	0.99
52_L	109_A	1.482	0.99
579_E	583_L	1.482	0.99
23_V	92_L	1.479	0.99
163_G	262_I	1.471	0.99
179_K	234_E	1.460	0.99
41_V	105_G	1.458	0.99
57_A	486_G	1.458	0.99
111_R	143_G	1.453	0.99
279_A	609_A	1.452	0.99
341_Q	345_L	1.448	0.99
216_I	220_L	1.446	0.99
376_I	479_L	1.442	0.99
649_R	658_L	1.435	0.99
512_P	516_A	1.434	0.99
107_Y	138_E	1.430	0.99
324_F	337_Y	1.430	0.99
295_L	559_F	1.423	0.99
125_A	483_E	1.422	0.99
399_E	636_R	1.417	0.99
357_F	464_V	1.415	0.99
36_N	60_D	1.415	0.99
26_V	66_I	1.412	0.99
310_E	314_A	1.402	0.99
205_K	211_L	1.394	0.99
318_A	322_A	1.391	0.99
321_K	327_D	1.386	0.99
182_T	209_G	1.386	0.99
309_G	549_L	1.383	0.99
31_N	35_E	1.381	0.99
259_M	573_I	1.381	0.99
632_G	635_N	1.371	0.99
200_A	203_E	1.369	0.99
423_M	477_H	1.369	0.99
282_S	286_K	1.368	0.99
372_R	517_F	1.366	0.99
623_D	665_R	1.362	0.99
296_D	300_D	1.353	0.99
154_E	158_R	1.337	0.99
314_A	317_R	1.337	0.99
320_A	327_D	1.328	0.99
26_V	67_F	1.327	0.99
219_Y	235_M	1.326	0.99
369_V	505_M	1.324	0.99
19_P	81_E	1.324	0.99
626_S	674_E	1.321	0.98
200_A	204_A	1.316	0.98
201_Q	211_L	1.312	0.98
521_H	524_T	1.301	0.98
199_K	208_E	1.299	0.98
111_R	138_E	1.284	0.98
536_M	539_A	1.283	0.98
177_W	234_E	1.283	0.98
431_R	481_R	1.277	0.98
656_M	666_E	1.276	0.98
370_V	471_F	1.271	0.98
359_E	412_Y	1.269	0.98
178_T	211_L	1.269	0.98
239_Y	242_R	1.265	0.98
626_S	629_E	1.264	0.98
184_E	210_Y	1.263	0.98
114_R	134_L	1.260	0.98
151_R	155_I	1.259	0.98
27_T	31_N	1.257	0.98
42_A	105_G	1.257	0.98
390_D	450_R	1.256	0.98
290_N	293_Q	1.252	0.98
374_Y	642_F	1.252	0.98
259_M	596_P	1.252	0.98
17_I	21_H	1.248	0.98
574_L	578_A	1.247	0.98
180_L	209_G	1.246	0.98
114_R	117_D	1.239	0.98
191_P	225_Y	1.232	0.98
134_L	138_E	1.227	0.98
21_H	25_A	1.227	0.98
80_P	84_E	1.220	0.97
403_L	439_K	1.214	0.97
72_H	443_Y	1.208	0.97
107_Y	134_L	1.205	0.97
531_E	534_D	1.202	0.97
341_Q	542_Y	1.201	0.97
152_Y	156_A	1.200	0.97
368_E	372_R	1.197	0.97
359_E	459_F	1.193	0.97
293_Q	296_D	1.191	0.97
642_F	647_L	1.191	0.97
656_M	660_K	1.189	0.97
625_F	633_I	1.184	0.97
631_E	638_T	1.183	0.97
295_L	563_A	1.180	0.97
481_R	648_S	1.180	0.97
561_L	596_P	1.171	0.97
99_W	153_G	1.171	0.97
40_V	52_L	1.169	0.97
182_T	208_E	1.167	0.97
198_A	218_S	1.164	0.97
85_A	89_T	1.162	0.97
657_D	660_K	1.160	0.97
295_L	299_T	1.158	0.97
203_E	207_L	1.158	0.97
397_Y	403_L	1.158	0.97
615_L	676_Y	1.157	0.96
222_V	235_M	1.154	0.96
173_A	243_A	1.154	0.96
156_A	269_L	1.154	0.96
494_P	655_P	1.153	0.96
313_L	329_L	1.149	0.96
280_F	292_Q	1.149	0.96
77_K	416_N	1.149	0.96
403_L	406_S	1.145	0.96
23_V	89_T	1.143	0.96
368_E	371_K	1.138	0.96
229_Q	330_Q	1.138	0.96
146_K	149_Q	1.134	0.96
22_V	73_L	1.134	0.96
181_V	231_L	1.129	0.96
550_R	554_F	1.124	0.96
136_D	486_G	1.122	0.96
451_P	457_A	1.118	0.96
398_D	404_R	1.115	0.96
165_Q	169_N	1.115	0.96
338_S	543_Q	1.114	0.96
9_F	403_L	1.113	0.96
283_L	294_V	1.103	0.95
161_E	165_Q	1.100	0.95
299_T	556_L	1.099	0.95
139_L	281_K	1.099	0.95
33_C	59_V	1.091	0.95
212_L	218_S	1.091	0.95
318_A	321_K	1.088	0.95
378_A	396_L	1.086	0.95
320_A	329_L	1.083	0.95
377_T	397_Y	1.083	0.95
487_V	651_G	1.079	0.95
108_K	112_D	1.078	0.95
112_D	116_G	1.076	0.95
74_N	82_L	1.074	0.95
386_V	393_F	1.073	0.95
169_N	253_W	1.072	0.95
313_L	317_R	1.065	0.94
430_M	438_Q	1.062	0.94
579_E	582_K	1.059	0.94
659_F	663_R	1.059	0.94
129_A	484_T	1.057	0.94
35_E	39_R	1.057	0.94
256_S	597_H	1.053	0.94
504_F	642_F	1.053	0.94
150_Q	153_G	1.053	0.94
260_E	264_A	1.052	0.94
26_V	89_T	1.045	0.94
442_A	477_H	1.043	0.94
456_P	522_Y	1.042	0.94
190_M	198_A	1.042	0.94
294_V	559_F	1.041	0.94
133_A	486_G	1.040	0.94
74_N	86_Y	1.040	0.94
362_A	464_V	1.037	0.94
219_Y	239_Y	1.036	0.94
48_T	55_P	1.035	0.94
336_Y	340_K	1.034	0.94
398_D	643_L	1.032	0.93
76_V	445_T	1.028	0.93
258_V	262_I	1.027	0.93
560_R	580_I	1.027	0.93
323_E	344_H	1.021	0.93
264_A	268_E	1.021	0.93
38_E	103_H	1.019	0.93
364_N	368_E	1.017	0.93
426_C	443_Y	1.015	0.93
359_E	411_L	1.015	0.93
36_N	40_V	1.014	0.93
339_E	342_K	1.012	0.93
38_E	105_G	1.012	0.93
27_T	30_L	1.010	0.93
511_E	625_F	1.009	0.93
387_W	391_V	1.008	0.93
329_L	337_Y	1.007	0.93
142_I	149_Q	1.007	0.93
656_M	667_P	1.004	0.92
560_R	583_L	1.004	0.92
363_V	392_R	1.003	0.92
169_N	258_V	1.001	0.92
201_Q	205_K	0.999	0.92
348_I	536_M	0.997	0.92
98_T	156_A	0.994	0.92
222_V	226_C	0.994	0.92
520_G	525_G	0.993	0.92
9_F	13_P	0.992	0.92
108_K	111_R	0.992	0.92
116_G	119_Y	0.990	0.92
107_Y	143_G	0.986	0.92
177_W	235_M	0.985	0.92
184_E	192_E	0.982	0.92
427_V	441_V	0.981	0.92
125_A	487_V	0.979	0.92
507_N	621_A	0.975	0.91
395_E	403_L	0.971	0.91
19_P	79_S	0.970	0.91
645_N	653_E	0.969	0.91
511_E	629_E	0.965	0.91
618_D	621_A	0.963	0.91
637_E	641_S	0.962	0.91
73_L	77_K	0.961	0.91
528_L	533_L	0.959	0.91
548_I	615_L	0.958	0.91
425_D	491_S	0.956	0.91
306_R	549_L	0.955	0.90
205_K	415_E	0.953	0.90
343_Q	347_S	0.953	0.90
19_P	85_A	0.951	0.90
668_Q	671_A	0.949	0.90
575_E	578_A	0.947	0.90
34_R	38_E	0.944	0.90
386_V	408_Y	0.944	0.90
621_A	675_H	0.942	0.90
152_Y	269_L	0.940	0.90
35_E	38_E	0.939	0.90
126_Q	483_E	0.939	0.90
363_V	409_L	0.939	0.90
560_R	564_E	0.936	0.90
179_K	182_T	0.936	0.90
184_E	199_K	0.935	0.90
512_P	533_L	0.933	0.89
257_K	260_E	0.932	0.89
87_E	165_Q	0.931	0.89
155_I	159_L	0.931	0.89
20_E	81_E	0.928	0.89
291_P	559_F	0.928	0.89
180_L	208_E	0.926	0.89
530_K	533_L	0.925	0.89
181_V	212_L	0.924	0.89
233_E	330_Q	0.922	0.89
101_G	136_D	0.922	0.89
544_A	676_Y	0.920	0.89
124_T	653_E	0.917	0.89
428_G	491_S	0.910	0.88
323_E	337_Y	0.909	0.88
11_L	408_Y	0.908	0.88
421_A	498_V	0.907	0.88
487_V	652_S	0.903	0.88
47_Y	109_A	0.903	0.88
49_W	126_Q	0.901	0.88
352_Q	355_P	0.899	0.88
494_P	654_E	0.898	0.88
181_V	210_Y	0.897	0.88
119_Y	127_K	0.896	0.87
127_K	130_V	0.896	0.87
288_A	294_V	0.895	0.87
119_Y	131_D	0.895	0.87
295_L	560_R	0.892	0.87
266_R	562_H	0.890	0.87
38_E	41_V	0.890	0.87
458_L	522_Y	0.889	0.87
300_D	304_R	0.888	0.87
448_F	459_F	0.885	0.87
157_T	161_E	0.884	0.87
37_V	56_L	0.883	0.87
21_H	24_P	0.881	0.87
37_V	100_V	0.875	0.86
330_Q	588_P	0.875	0.86
553_E	581_K	0.872	0.86
376_I	404_R	0.872	0.86
119_Y	130_V	0.871	0.86
27_T	88_Q	0.869	0.86
323_E	340_K	0.868	0.86
29_A	62_V	0.868	0.86
421_A	466_T	0.868	0.86
510_W	536_M	0.867	0.86
244_S	256_S	0.865	0.86
147_E	150_Q	0.864	0.85
397_Y	401_N	0.863	0.85
58_E	433_A	0.862	0.85
277_N	291_P	0.861	0.85
27_T	89_T	0.860	0.85
83_R	172_D	0.860	0.85
454_G	523_E	0.859	0.85
658_L	661_R	0.855	0.85
262_I	603_F	0.855	0.85
81_E	84_E	0.855	0.85
48_T	51_N	0.855	0.85
578_A	582_K	0.854	0.85
155_I	269_L	0.854	0.85
47_Y	112_D	0.852	0.85
372_R	513_E	0.852	0.85
113_L	130_V	0.851	0.85
190_M	226_C	0.850	0.85
280_F	284_A	0.850	0.85
236_Y	331_P	0.848	0.84
198_A	222_V	0.847	0.84
260_E	573_I	0.847	0.84
516_A	527_P	0.846	0.84
366_L	467_L	0.844	0.84
645_N	649_R	0.844	0.84
462_D	465_I	0.840	0.84
295_L	556_L	0.840	0.84
340_K	343_Q	0.839	0.84
216_I	239_Y	0.839	0.84
222_V	231_L	0.835	0.83
529_P	532_L	0.835	0.83
139_L	275_F	0.835	0.83
192_E	195_L	0.833	0.83
135_R	285_T	0.832	0.83
267_H	566_R	0.830	0.83
117_D	127_K	0.829	0.83
167_S	600_S	0.829	0.83
47_Y	113_L	0.827	0.83
477_H	490_I	0.827	0.83
622_A	675_H	0.827	0.83
19_P	82_L	0.825	0.83
371_K	376_I	0.825	0.83
356_Y	532_L	0.824	0.83
582_K	588_P	0.823	0.83
26_V	30_L	0.823	0.83
236_Y	591_S	0.823	0.83
645_N	658_L	0.822	0.83
121_T	127_K	0.820	0.82
53_C	130_V	0.818	0.82
313_L	587_V	0.816	0.82
300_D	669_L	0.815	0.82
504_F	508_W	0.814	0.82
515_L	533_L	0.813	0.82
548_I	676_Y	0.813	0.82
307_P	310_E	0.813	0.82
201_Q	204_A	0.811	0.82
630_E	665_R	0.811	0.82
188_A	228_N	0.810	0.82
344_H	347_S	0.807	0.81
294_V	298_L	0.807	0.81
175_M	215_D	0.806	0.81
407_F	478_M	0.804	0.81
375_G	399_E	0.804	0.81
229_Q	332_W	0.802	0.81
623_D	663_R	0.801	0.81
301_L	552_L	0.800	0.81
114_R	131_D	0.800	0.81
363_V	467_L	0.800	0.81
123_N	484_T	0.799	0.81
607_Y	614_Y	0.798	0.81
40_V	59_V	0.798	0.81
23_V	85_A	0.798	0.81
105_G	108_K	0.797	0.81
320_A	325_G	0.795	0.80
395_E	406_S	0.795	0.80
504_F	624_A	0.795	0.80
236_Y	240_S	0.795	0.80
79_S	416_N	0.793	0.80
551_Q	615_L	0.792	0.80
183_D	210_Y	0.792	0.80
135_R	284_A	0.792	0.80
507_N	625_F	0.792	0.80
88_Q	92_L	0.791	0.80
378_A	407_F	0.791	0.80
516_A	533_L	0.790	0.80
18_L	24_P	0.787	0.80
263_L	561_L	0.787	0.80
469_H	499_E	0.786	0.80
226_C	231_L	0.786	0.80
128_K	651_G	0.785	0.80
74_N	78_N	0.785	0.80
11_L	406_S	0.783	0.79
659_F	667_P	0.783	0.79
52_L	55_P	0.780	0.79
343_Q	349_S	0.780	0.79
54_Q	58_E	0.780	0.79
155_I	268_E	0.780	0.79
369_V	514_A	0.780	0.79
175_M	416_N	0.778	0.79
346_Y	539_A	0.778	0.79
308_Q	678_I	0.775	0.79
276_E	292_Q	0.775	0.79
102_Q	153_G	0.772	0.78
571_A	579_E	0.772	0.78
601_H	611_Y	0.771	0.78
165_Q	168_N	0.771	0.78
507_N	675_H	0.770	0.78
319_F	341_Q	0.769	0.78
233_E	332_W	0.769	0.78
22_V	70_V	0.769	0.78
311_K	314_A	0.768	0.78
556_L	584_V	0.767	0.78
643_L	648_S	0.766	0.78
313_L	334_I	0.765	0.78
544_A	548_I	0.764	0.78
407_F	444_L	0.762	0.78
670_D	674_E	0.760	0.77
58_E	432_K	0.757	0.77
186_E	230_A	0.757	0.77
637_E	644_D	0.756	0.77
228_N	234_E	0.756	0.77
387_W	426_C	0.755	0.77
203_E	453_N	0.754	0.77
260_E	570_G	0.754	0.77
207_L	211_L	0.753	0.77
269_L	281_K	0.752	0.77
381_R	384_V	0.751	0.76
199_K	209_G	0.751	0.76
654_E	657_D	0.750	0.76
347_S	535_K	0.750	0.76
158_R	257_K	0.750	0.76
423_M	442_A	0.748	0.76
49_W	53_C	0.747	0.76
371_K	378_A	0.746	0.76
627_R	632_G	0.743	0.76
89_T	92_L	0.743	0.76
120_A	130_V	0.741	0.76
627_R	630_E	0.741	0.76
128_K	131_D	0.741	0.76
165_Q	258_V	0.740	0.75
190_M	222_V	0.740	0.75
34_R	96_Y	0.740	0.75
352_Q	532_L	0.737	0.75
511_E	633_I	0.736	0.75
67_F	71_S	0.736	0.75
458_L	521_H	0.735	0.75
665_R	668_Q	0.734	0.75
36_N	59_V	0.733	0.75
22_V	82_L	0.733	0.75
357_F	461_H	0.732	0.75
188_A	336_Y	0.732	0.75
32_D	35_E	0.732	0.75
431_R	437_L	0.731	0.75
370_V	378_A	0.729	0.74
370_V	396_L	0.729	0.74
321_K	325_G	0.729	0.74
470_E	473_H	0.728	0.74
190_M	194_A	0.728	0.74
191_P	194_A	0.728	0.74
61_D	430_M	0.727	0.74
193_S	351_E	0.726	0.74
271_Q	566_R	0.725	0.74
520_G	527_P	0.725	0.74
317_R	329_L	0.725	0.74
341_Q	346_Y	0.724	0.74
296_D	299_T	0.723	0.74
528_L	532_L	0.722	0.74
202_A	211_L	0.722	0.74
360_N	392_R	0.721	0.74
154_E	157_T	0.720	0.73
77_K	82_L	0.720	0.73
370_V	475_L	0.719	0.73
308_Q	545_A	0.719	0.73
649_R	652_S	0.717	0.73
627_R	635_N	0.717	0.73
601_H	614_Y	0.716	0.73
460_T	463_E	0.715	0.73
113_L	120_A	0.714	0.73
489_G	498_V	0.713	0.73
57_A	485_A	0.712	0.73
40_V	55_P	0.712	0.73
627_R	663_R	0.711	0.72
271_Q	276_E	0.709	0.72
519_S	528_L	0.707	0.72
76_V	387_W	0.706	0.72
159_L	265_L	0.706	0.72
560_R	579_E	0.706	0.72
599_F	611_Y	0.705	0.72
117_D	131_D	0.705	0.72
375_G	398_D	0.705	0.72
404_R	478_M	0.704	0.72
58_E	430_M	0.704	0.72
104_E	145_P	0.704	0.72
310_E	317_R	0.702	0.72
321_K	328_E	0.701	0.71
531_E	535_K	0.701	0.71
384_V	393_F	0.700	0.71
380_E	383_D	0.700	0.71
194_A	222_V	0.697	0.71
229_Q	333_D	0.697	0.71
182_T	186_E	0.697	0.71
132_N	135_R	0.697	0.71
133_A	136_D	0.696	0.71
329_L	334_I	0.696	0.71
311_K	315_Q	0.695	0.71
72_H	426_C	0.693	0.71
34_R	92_L	0.693	0.71
644_D	649_R	0.692	0.70
442_A	490_I	0.691	0.70
551_Q	554_F	0.689	0.70
267_H	564_E	0.688	0.70
148_K	271_Q	0.685	0.70
312_E	543_Q	0.685	0.70
552_L	615_L	0.684	0.70
469_H	473_H	0.682	0.69
161_E	261_E	0.681	0.69
78_N	416_N	0.681	0.69
394_F	409_L	0.680	0.69
552_L	556_L	0.680	0.69
131_D	135_R	0.680	0.69
14_F	17_I	0.680	0.69
49_W	55_P	0.679	0.69
342_K	542_Y	0.679	0.69
72_H	76_V	0.678	0.69
79_S	82_L	0.678	0.69
381_R	393_F	0.677	0.69
149_Q	653_E	0.675	0.69
427_V	438_Q	0.675	0.69
600_S	604_A	0.673	0.68
411_L	467_L	0.673	0.68
412_Y	451_P	0.672	0.68
220_L	335_A	0.671	0.68
507_N	622_A	0.671	0.68
546_L	549_L	0.668	0.68
78_N	83_R	0.667	0.68
377_T	401_N	0.666	0.68
412_Y	457_A	0.666	0.68
482_I	652_S	0.666	0.68
128_K	654_E	0.664	0.67
557_F	577_L	0.664	0.67
90_L	94_S	0.660	0.67
187_L	195_L	0.659	0.67
331_P	590_P	0.659	0.67
92_L	95_E	0.657	0.66
61_D	65_R	0.657	0.66
95_E	99_W	0.656	0.66
631_E	641_S	0.656	0.66
469_H	614_Y	0.656	0.66
315_Q	341_Q	0.655	0.66
37_V	103_H	0.654	0.66
197_A	450_R	0.653	0.66
298_L	556_L	0.653	0.66
619_V	667_P	0.653	0.66
267_H	565_F	0.652	0.66
283_L	288_A	0.651	0.66
26_V	85_A	0.651	0.66
476_H	501_P	0.651	0.66
490_I	498_V	0.651	0.66
278_Y	282_S	0.651	0.66
316_L	329_L	0.649	0.66
381_R	406_S	0.647	0.65
17_I	25_A	0.646	0.65
110_Y	133_A	0.646	0.65
30_L	93_L	0.644	0.65
599_F	602_I	0.644	0.65
409_L	444_L	0.643	0.65
317_R	327_D	0.642	0.65
470_E	506_E	0.642	0.65
319_F	323_E	0.641	0.65
304_R	669_L	0.641	0.65
534_D	537_L	0.640	0.64
71_S	93_L	0.638	0.64
275_F	281_K	0.638	0.64
448_F	457_A	0.637	0.64
224_T	545_A	0.636	0.64
560_R	576_T	0.636	0.64
557_F	561_L	0.635	0.64
55_P	130_V	0.635	0.64
107_Y	114_R	0.635	0.64
33_C	100_V	0.634	0.64
84_E	87_E	0.633	0.64
637_E	640_Q	0.632	0.63
358_P	520_G	0.630	0.63
30_L	33_C	0.630	0.63
306_R	583_L	0.630	0.63
581_K	593_G	0.630	0.63
178_T	205_K	0.629	0.63
424_D	445_T	0.628	0.63
508_W	634_F	0.627	0.63
470_E	499_E	0.627	0.63
577_L	595_F	0.626	0.63
357_F	528_L	0.626	0.63
30_L	96_Y	0.625	0.63
324_F	327_D	0.624	0.62
236_Y	332_W	0.620	0.62
124_T	127_K	0.620	0.62
255_N	258_V	0.620	0.62
549_L	552_L	0.620	0.62
303_K	310_E	0.620	0.62
190_M	212_L	0.620	0.62
36_N	39_R	0.619	0.62
181_V	222_V	0.619	0.62
260_E	571_A	0.619	0.62
88_Q	91_P	0.618	0.62
30_L	34_R	0.617	0.62
114_R	127_K	0.617	0.62
473_H	499_E	0.617	0.62
179_K	222_V	0.617	0.62
495_W	613_S	0.616	0.61
181_V	228_N	0.614	0.61
369_V	468_F	0.614	0.61
631_E	637_E	0.614	0.61
625_F	646_I	0.613	0.61
561_L	576_T	0.613	0.61
72_H	424_D	0.612	0.61
566_R	569_Q	0.612	0.61
29_A	33_C	0.611	0.61
57_A	60_D	0.611	0.61
469_H	506_E	0.610	0.61
428_G	488_S	0.610	0.61
508_W	633_I	0.610	0.61
600_S	613_S	0.607	0.60
44_G	51_N	0.607	0.60
561_L	602_I	0.606	0.60
319_F	543_Q	0.606	0.60
106_L	137_F	0.605	0.60
118_H	127_K	0.605	0.60
417_K	502_S	0.604	0.60
31_N	34_R	0.604	0.60
627_R	638_T	0.604	0.60
580_I	584_V	0.603	0.60
271_Q	277_N	0.602	0.60
481_R	644_D	0.602	0.60
633_I	638_T	0.600	0.59
72_H	387_W	0.599	0.59
47_Y	52_L	0.598	0.59
387_W	445_T	0.598	0.59
291_P	563_A	0.597	0.59
199_K	202_A	0.597	0.59
532_L	536_M	0.597	0.59
466_T	601_H	0.597	0.59
321_K	326_V	0.595	0.59
280_F	563_A	0.595	0.59
286_K	617_A	0.595	0.59
172_D	253_W	0.594	0.59
75_S	424_D	0.593	0.59
188_A	340_K	0.592	0.58
406_S	439_K	0.592	0.58
299_T	303_K	0.592	0.58
66_I	93_L	0.592	0.58
302_A	584_V	0.592	0.58
235_M	239_Y	0.591	0.58
154_E	268_E	0.591	0.58
418_R	422_W	0.591	0.58
546_L	550_R	0.591	0.58
117_D	121_T	0.590	0.58
624_A	659_F	0.590	0.58
139_L	285_T	0.589	0.58
46_P	116_G	0.588	0.58
423_M	489_G	0.588	0.58
256_S	573_I	0.587	0.58
204_A	415_E	0.587	0.58
18_L	81_E	0.586	0.58
99_W	103_H	0.585	0.58
473_H	506_E	0.584	0.57
607_Y	611_Y	0.583	0.57
323_E	336_Y	0.582	0.57
194_A	221_P	0.582	0.57
500_L	505_M	0.581	0.57
599_F	607_Y	0.581	0.57
355_P	522_Y	0.580	0.57
97_S	101_G	0.580	0.57
69_P	73_L	0.579	0.57
307_P	311_K	0.578	0.57
78_N	86_Y	0.578	0.57
499_E	502_S	0.578	0.57
231_L	234_E	0.578	0.57
56_L	133_A	0.578	0.57
548_I	555_G	0.577	0.57
395_E	405_G	0.577	0.57
24_P	35_E	0.577	0.57
409_L	474_G	0.576	0.56
416_N	559_F	0.576	0.56
11_L	441_V	0.576	0.56
335_A	338_S	0.576	0.56
508_W	625_F	0.576	0.56
30_L	92_L	0.575	0.56
230_A	234_E	0.575	0.56
282_S	608_A	0.575	0.56
328_E	588_P	0.575	0.56
601_H	607_Y	0.574	0.56
377_T	398_D	0.574	0.56
64_G	425_D	0.573	0.56
500_L	504_F	0.573	0.56
86_Y	164_N	0.572	0.56
414_R	417_K	0.572	0.56
364_N	371_K	0.571	0.56
499_E	614_Y	0.571	0.56
465_I	509_C	0.571	0.56
138_E	284_A	0.571	0.56
64_G	428_G	0.571	0.56
145_P	149_Q	0.571	0.56
320_A	324_F	0.570	0.56
312_E	545_A	0.569	0.56
174_T	419_G	0.569	0.56
74_N	83_R	0.569	0.56
615_L	624_A	0.569	0.56
33_C	36_N	0.568	0.55
372_R	634_F	0.568	0.55
425_D	488_S	0.568	0.55
355_P	523_E	0.567	0.55
96_Y	99_W	0.567	0.55
316_L	341_Q	0.565	0.55
189_G	226_C	0.565	0.55
363_V	378_A	0.565	0.55
641_S	661_R	0.564	0.55
423_M	490_I	0.564	0.55
54_Q	129_A	0.564	0.55
132_N	486_G	0.564	0.55
299_T	560_R	0.563	0.55
499_E	506_E	0.563	0.55
377_T	399_E	0.562	0.55
288_A	616_W	0.562	0.55
654_E	658_L	0.562	0.55
537_L	540_K	0.562	0.55
476_H	493_V	0.562	0.55
305_A	549_L	0.561	0.54
570_G	575_E	0.561	0.54
120_A	127_K	0.561	0.54
353_L	532_L	0.561	0.54
623_D	659_F	0.561	0.54
303_K	307_P	0.561	0.54
346_Y	535_K	0.560	0.54
557_F	576_T	0.560	0.54
25_A	66_I	0.560	0.54
495_W	498_V	0.559	0.54
10_E	13_P	0.559	0.54
301_L	669_L	0.559	0.54
298_L	552_L	0.558	0.54
50_E	118_H	0.556	0.54
29_A	59_V	0.555	0.54
264_A	569_Q	0.555	0.54
423_M	498_V	0.555	0.54
262_I	608_A	0.555	0.54
8_P	65_R	0.554	0.54
8_P	13_P	0.554	0.54
158_R	265_L	0.554	0.54
287_M	500_L	0.553	0.53
24_P	27_T	0.552	0.53
225_Y	239_Y	0.552	0.53
482_I	488_S	0.551	0.53
642_F	646_I	0.551	0.53
312_E	316_L	0.550	0.53
10_E	427_V	0.549	0.53
611_Y	614_Y	0.549	0.53
293_Q	297_F	0.549	0.53
298_L	555_G	0.548	0.53
665_R	671_A	0.548	0.53
621_A	674_E	0.546	0.52
428_G	485_A	0.546	0.52
205_K	213_T	0.545	0.52
634_F	639_G	0.545	0.52
533_L	537_L	0.545	0.52
185_A	195_L	0.545	0.52
268_E	271_Q	0.545	0.52
405_G	439_K	0.544	0.52
21_H	66_I	0.544	0.52
407_F	474_G	0.544	0.52
110_Y	134_L	0.543	0.52
263_L	564_E	0.541	0.52
448_F	467_L	0.540	0.52
17_I	69_P	0.540	0.52
221_P	224_T	0.540	0.52
602_I	608_A	0.540	0.52
44_G	52_L	0.539	0.52
620_L	659_F	0.539	0.52
544_A	547_F	0.538	0.51
51_N	109_A	0.538	0.51
360_N	364_N	0.537	0.51
33_C	40_V	0.537	0.51
33_C	37_V	0.536	0.51
259_M	263_L	0.535	0.51
183_D	228_N	0.535	0.51
98_T	153_G	0.535	0.51
186_E	222_V	0.535	0.51
43_Q	47_Y	0.535	0.51
317_R	320_A	0.534	0.51
300_D	303_K	0.534	0.51
162_L	261_E	0.534	0.51
622_A	672_M	0.534	0.51
402_E	481_R	0.534	0.51
404_R	643_L	0.533	0.51
548_I	672_M	0.531	0.51
276_E	565_F	0.531	0.51
174_T	242_R	0.531	0.51
179_K	235_M	0.530	0.50
260_E	569_Q	0.530	0.50
49_W	484_T	0.530	0.50
384_V	387_W	0.530	0.50
502_S	601_H	0.530	0.50
203_E	206_E	0.529	0.50
489_G	650_G	0.529	0.50
369_V	634_F	0.529	0.50
37_V	41_V	0.529	0.50
219_Y	255_N	0.528	0.50
342_K	350_D	0.528	0.50
413_A	420_G	0.527	0.50
364_N	520_G	0.526	0.50
526_E	531_E	0.525	0.50
354_R	460_T	0.525	0.50
559_F	678_I	0.524	0.50
200_A	450_R	0.524	0.50
70_V	85_A	0.524	0.50
152_Y	273_L	0.523	0.49
561_L	573_I	0.523	0.49
225_Y	343_Q	0.523	0.49
557_F	596_P	0.522	0.49
363_V	366_L	0.522	0.49
430_M	485_A	0.522	0.49
115_D	531_E	0.521	0.49
326_V	337_Y	0.521	0.49
305_A	648_S	0.521	0.49
185_A	389_P	0.520	0.49
309_G	651_G	0.520	0.49
199_K	206_E	0.520	0.49
643_L	647_L	0.519	0.49
58_E	485_A	0.519	0.49
302_A	549_L	0.519	0.49
511_E	634_F	0.518	0.49
318_A	344_H	0.518	0.49
197_A	201_Q	0.517	0.49
468_F	514_A	0.517	0.49
543_Q	546_L	0.517	0.49
61_D	64_G	0.517	0.49
309_G	586_V	0.517	0.49
229_Q	233_E	0.516	0.49
469_H	502_S	0.516	0.49
470_E	614_Y	0.515	0.48
397_Y	439_K	0.515	0.48
315_Q	318_A	0.515	0.48
127_K	276_E	0.515	0.48
514_A	517_F	0.515	0.48
17_I	24_P	0.514	0.48
508_W	628_F	0.514	0.48
68_S	485_A	0.514	0.48
202_A	254_D	0.513	0.48
85_A	88_Q	0.513	0.48
75_S	418_R	0.513	0.48
45_A	48_T	0.513	0.48
201_Q	213_T	0.511	0.48
16_K	385_D	0.511	0.48
296_D	389_P	0.510	0.48
578_A	588_P	0.510	0.48
132_N	487_V	0.510	0.48
374_Y	647_L	0.509	0.48
42_A	148_K	0.508	0.47
167_S	604_A	0.508	0.47
447_N	464_V	0.507	0.47
346_Y	536_M	0.507	0.47
20_E	323_E	0.507	0.47
339_E	347_S	0.507	0.47
60_D	100_V	0.507	0.47
548_I	551_Q	0.507	0.47
341_Q	344_H	0.506	0.47
88_Q	318_A	0.506	0.47
30_L	103_H	0.506	0.47
198_A	201_Q	0.504	0.47
490_I	495_W	0.503	0.47
495_W	617_A	0.503	0.47
115_D	186_E	0.503	0.47
418_R	613_S	0.503	0.47
532_L	535_K	0.503	0.47
229_Q	320_A	0.502	0.47
286_K	495_W	0.502	0.47
113_L	116_G	0.502	0.47
541_N	544_A	0.502	0.47
411_L	445_T	0.501	0.47
178_T	207_L	0.500	0.46
353_L	528_L	0.500	0.46
185_A	188_A	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ka7A	1	0.9882	100	0.205	Contact Map
2o3eA	1	0.9632	100	0.211	Contact Map
1y791	1	0.9882	100	0.222	Contact Map
2o36A	1	0.9485	100	0.256	Contact Map
1r42A	1	0.7765	100	0.58	Contact Map
4ca6A	1	0.7897	100	0.587	Contact Map
4c2oA	1	0.7632	100	0.601	Contact Map
3sksA	1	0.7691	100	0.604	Contact Map
3ahnA	1	0.7882	100	0.614	Contact Map
2qr4A	2	0.7221	100	0.618	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0164 seconds.