DING - ECOLI - GREMLIN Contacts

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DING - Probable ATP-dependent helicase DinG

UniProt:	P27296	Sequences: MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQLDLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNEEQHIAEMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11357
Length:	716 (610)
Sequences:	3781 (2844)
Seq/√Len:	115.2

ECOLI - DING YOAA
BACSU - DING YPVA
HALSA - Q9HMP9 Q9HQ08 Q9HMM1
SULSO - Q980I2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
519_A	553_Y	5.056	1.00
68_G	246_V	4.671	1.00
227_V	247_L	4.619	1.00
541_F	550_F	4.369	1.00
250_G	457_V	4.331	1.00
525_F	609_H	4.210	1.00
42_L	244_L	4.059	1.00
554_V	589_V	3.884	1.00
529_V	537_M	3.879	1.00
29_A	33_Q	3.859	1.00
533_K	537_M	3.857	1.00
541_F	589_V	3.855	1.00
34_M	52_I	3.713	1.00
630_L	635_R	3.585	1.00
536_G	606_S	3.458	1.00
528_Q	668_V	3.136	1.00
97_L	109_F	3.123	1.00
41_T	50_L	2.878	1.00
573_V	577_R	2.877	1.00
26_I	661_H	2.804	1.00
110_T	217_A	2.802	1.00
172_R	184_W	2.791	1.00
37_D	486_V	2.766	1.00
562_L	586_S	2.763	1.00
48_R	484_R	2.730	1.00
551_L	563_V	2.676	1.00
569_R	573_V	2.669	1.00
525_F	539_V	2.660	1.00
568_P	573_V	2.644	1.00
669_I	674_L	2.641	1.00
68_G	79_L	2.638	1.00
315_I	318_L	2.617	1.00
544_G	591_L	2.543	1.00
657_L	665_G	2.542	1.00
595_A	653_Q	2.541	1.00
61_T	92_I	2.513	1.00
169_D	174_H	2.454	1.00
34_M	458_T	2.413	1.00
444_L	449_W	2.405	1.00
445_E	450_R	2.392	1.00
162_D	167_K	2.383	1.00
305_N	309_E	2.378	1.00
568_P	572_L	2.368	1.00
522_A	553_Y	2.316	1.00
601_K	660_S	2.300	1.00
247_L	253_L	2.298	1.00
635_R	640_V	2.271	1.00
472_Q	485_F	2.233	1.00
493_N	497_Q	2.211	1.00
528_Q	607_Q	2.206	1.00
40_K	46_E	2.183	1.00
654_V	667_V	2.173	1.00
536_G	559_L	2.166	1.00
529_V	587_V	2.152	1.00
607_Q	668_V	2.151	1.00
30_P	488_L	2.141	1.00
535_L	603_D	2.116	1.00
537_M	607_Q	2.101	1.00
526_R	557_L	2.073	1.00
650_L	669_I	2.053	1.00
603_D	606_S	2.045	1.00
252_H	596_E	2.013	1.00
545_R	549_R	1.988	1.00
309_E	312_Y	1.983	1.00
524_F	670_Y	1.976	1.00
568_P	577_R	1.950	1.00
560_M	583_G	1.939	1.00
463_R	487_A	1.904	1.00
112_A	220_V	1.901	1.00
194_C	199_C	1.896	1.00
547_M	563_V	1.889	1.00
311_L	315_I	1.884	1.00
569_R	572_L	1.872	1.00
41_T	454_H	1.869	1.00
236_V	239_D	1.869	1.00
82_S	224_H	1.858	1.00
32_R	36_A	1.852	1.00
51_A	471_L	1.844	1.00
560_M	584_E	1.814	1.00
51_A	475_S	1.808	1.00
639_E	678_N	1.806	1.00
647_S	683_L	1.797	1.00
609_H	670_Y	1.790	1.00
522_A	550_F	1.784	1.00
471_L	475_S	1.778	1.00
304_L	307_H	1.777	1.00
574_E	582_N	1.768	1.00
449_W	457_V	1.768	1.00
80_V	245_L	1.764	1.00
88_L	91_Q	1.759	1.00
41_T	48_R	1.740	1.00
51_A	472_Q	1.739	1.00
630_L	641_Q	1.732	1.00
628_E	631_K	1.726	1.00
42_L	456_I	1.720	1.00
547_M	589_V	1.720	1.00
61_T	247_L	1.718	1.00
592_Q	649_N	1.713	1.00
64_Y	458_T	1.700	1.00
321_I	324_L	1.697	1.00
534_H	559_L	1.692	1.00
629_W	633_L	1.684	1.00
627_G	642_S	1.684	1.00
497_Q	658_I	1.679	1.00
523_A	557_L	1.674	1.00
310_E	313_E	1.672	1.00
544_G	547_M	1.669	1.00
86_V	89_Q	1.661	1.00
80_V	242_N	1.645	1.00
120_C	205_C	1.640	1.00
528_Q	609_H	1.639	1.00
90_D	94_S	1.624	1.00
111_A	221_V	1.618	1.00
628_E	632_S	1.612	1.00
631_K	637_P	1.611	1.00
264_S	434_H	1.606	1.00
650_L	683_L	1.598	1.00
79_L	246_V	1.573	1.00
308_C	311_L	1.573	1.00
606_S	664_W	1.560	1.00
395_M	398_A	1.558	1.00
83_T	89_Q	1.557	1.00
555_T	566_D	1.553	1.00
307_H	315_I	1.543	1.00
34_M	38_V	1.534	1.00
541_F	547_M	1.530	1.00
312_Y	316_A	1.523	1.00
544_G	548_Q	1.507	1.00
499_K	666_E	1.492	1.00
113_F	171_L	1.489	1.00
600_L	604_L	1.489	1.00
108_K	218_E	1.485	1.00
452_I	455_I	1.481	1.00
684_L	692_I	1.481	1.00
264_S	432_W	1.476	1.00
533_K	607_Q	1.468	1.00
505_M	524_F	1.463	1.00
81_V	92_I	1.455	1.00
361_G	364_E	1.454	1.00
301_P	307_H	1.443	1.00
37_D	484_R	1.439	1.00
156_C	159_L	1.439	1.00
77_K	243_L	1.434	1.00
120_C	199_C	1.418	1.00
583_G	586_S	1.416	1.00
527_K	530_E	1.415	1.00
506_R	520_E	1.404	1.00
572_L	577_R	1.404	1.00
254_P	474_M	1.397	1.00
33_Q	36_A	1.388	1.00
613_I	646_A	1.387	1.00
339_G	342_P	1.378	1.00
396_F	399_Q	1.371	1.00
569_R	577_R	1.363	1.00
312_Y	319_N	1.362	1.00
112_A	214_I	1.357	1.00
283_V	287_M	1.353	1.00
534_H	585_R	1.348	1.00
267_I	431_L	1.346	1.00
654_V	669_I	1.341	1.00
506_R	509_P	1.337	1.00
577_R	604_L	1.335	1.00
584_E	603_D	1.332	1.00
324_L	327_P	1.326	1.00
656_R	659_R	1.325	1.00
63_S	67_P	1.324	1.00
457_V	471_L	1.324	1.00
551_L	555_T	1.324	1.00
562_L	575_L	1.323	1.00
542_A	612_K	1.321	1.00
311_L	314_L	1.320	1.00
92_I	96_D	1.315	1.00
51_A	462_L	1.309	1.00
228_M	231_M	1.294	1.00
627_G	631_K	1.293	1.00
322_L	326_M	1.289	0.99
96_D	99_L	1.288	0.99
38_V	67_P	1.286	0.99
121_P	124_L	1.284	0.99
52_I	488_L	1.282	0.99
38_V	456_I	1.279	0.99
539_V	589_V	1.277	0.99
169_D	172_R	1.277	0.99
97_L	221_V	1.274	0.99
392_A	396_F	1.268	0.99
571_R	575_L	1.261	0.99
212_R	215_Q	1.256	0.99
309_E	313_E	1.248	0.99
228_M	234_E	1.248	0.99
30_P	489_D	1.245	0.99
357_E	364_E	1.245	0.99
572_L	588_L	1.243	0.99
93_Y	221_V	1.235	0.99
655_G	659_R	1.233	0.99
258_R	626_E	1.232	0.99
539_V	587_V	1.231	0.99
305_N	315_I	1.226	0.99
503_P	506_R	1.221	0.99
445_E	478_K	1.217	0.99
69_I	107_L	1.213	0.99
55_P	488_L	1.211	0.99
677_K	680_G	1.202	0.99
55_P	491_P	1.201	0.99
245_L	452_I	1.199	0.99
500_I	669_I	1.198	0.99
47_G	453_P	1.196	0.99
518_I	522_A	1.193	0.99
615_F	679_Y	1.193	0.99
73_R	218_E	1.191	0.99
304_L	311_L	1.188	0.99
550_F	553_Y	1.187	0.99
315_I	322_L	1.182	0.99
355_L	362_L	1.178	0.99
519_A	523_A	1.176	0.99
667_V	690_F	1.175	0.99
518_I	550_F	1.169	0.99
37_D	50_L	1.167	0.99
50_L	456_I	1.167	0.99
561_L	589_V	1.163	0.99
623_V	641_Q	1.163	0.99
302_E	305_N	1.161	0.99
255_D	645_S	1.159	0.99
85_N	91_Q	1.159	0.99
227_V	245_L	1.154	0.99
228_M	253_L	1.146	0.99
362_L	366_F	1.143	0.99
652_Q	655_G	1.142	0.99
608_V	657_L	1.138	0.99
559_L	585_R	1.137	0.99
569_R	594_F	1.134	0.99
86_V	91_Q	1.131	0.99
171_L	174_H	1.129	0.99
434_H	622_V	1.127	0.99
610_I	667_V	1.127	0.99
549_R	552_D	1.122	0.99
84_A	256_V	1.122	0.99
610_I	654_V	1.121	0.99
303_R	314_L	1.117	0.99
251_H	459_S	1.117	0.99
311_L	318_L	1.116	0.99
86_V	117_R	1.112	0.98
274_L	277_D	1.108	0.98
199_C	205_C	1.107	0.98
521_M	670_Y	1.107	0.98
28_R	31_Q	1.105	0.98
319_N	323_N	1.101	0.98
93_Y	111_A	1.093	0.98
119_V	124_L	1.092	0.98
156_C	160_K	1.090	0.98
609_H	668_V	1.090	0.98
522_A	554_V	1.088	0.98
37_D	40_K	1.080	0.98
615_F	643_L	1.080	0.98
49_H	454_H	1.080	0.98
245_L	455_I	1.079	0.98
315_I	326_M	1.078	0.98
89_Q	93_Y	1.077	0.98
364_E	367_L	1.075	0.98
636_Y	639_E	1.075	0.98
313_E	316_A	1.074	0.98
85_N	88_L	1.074	0.98
550_F	589_V	1.073	0.98
392_A	395_M	1.073	0.98
388_Q	391_R	1.069	0.98
307_H	327_P	1.069	0.98
28_R	54_A	1.069	0.98
230_A	233_S	1.064	0.98
500_I	503_P	1.063	0.98
316_A	324_L	1.061	0.98
85_N	96_D	1.060	0.98
319_N	322_L	1.053	0.98
49_H	52_I	1.050	0.98
308_C	314_L	1.047	0.98
357_E	361_G	1.040	0.98
335_R	338_M	1.038	0.98
318_L	322_L	1.034	0.98
468_F	485_F	1.034	0.98
155_R	158_K	1.034	0.98
562_L	583_G	1.034	0.98
228_M	257_A	1.026	0.97
506_R	510_S	1.026	0.97
244_L	454_H	1.025	0.97
367_L	371_S	1.024	0.97
540_L	595_A	1.023	0.97
319_N	324_L	1.019	0.97
560_M	586_S	1.015	0.97
419_W	621_P	1.014	0.97
384_R	388_Q	1.013	0.97
322_L	327_P	1.012	0.97
55_P	490_S	1.008	0.97
560_M	575_L	1.008	0.97
302_E	309_E	1.008	0.97
515_E	549_R	1.006	0.97
356_T	360_R	1.002	0.97
346_L	350_Q	0.999	0.97
93_Y	109_F	0.999	0.97
563_V	566_D	0.996	0.97
152_E	156_C	0.994	0.97
389_M	393_L	0.980	0.97
312_Y	315_I	0.980	0.97
350_Q	357_E	0.975	0.97
308_C	315_I	0.970	0.96
652_Q	659_R	0.963	0.96
37_D	488_L	0.963	0.96
385_L	392_A	0.963	0.96
89_Q	223_N	0.960	0.96
303_R	307_H	0.957	0.96
159_L	162_D	0.957	0.96
312_Y	322_L	0.954	0.96
491_P	602_G	0.953	0.96
501_V	668_V	0.952	0.96
508_E	672_K	0.951	0.96
302_E	306_A	0.950	0.96
320_N	324_L	0.942	0.96
521_M	525_F	0.941	0.96
122_R	200_Y	0.941	0.96
156_C	163_L	0.940	0.96
546_A	611_H	0.940	0.96
502_I	675_L	0.938	0.96
507_V	520_E	0.938	0.96
569_R	593_S	0.937	0.96
315_I	321_I	0.936	0.96
57_G	60_K	0.936	0.96
152_E	155_R	0.935	0.96
86_V	90_D	0.934	0.96
639_E	643_L	0.933	0.96
40_K	484_R	0.931	0.95
680_G	688_P	0.929	0.95
39_A	70_A	0.929	0.95
235_A	238_P	0.928	0.95
360_R	363_A	0.927	0.95
121_P	206_P	0.925	0.95
623_V	642_S	0.923	0.95
341_L	345_V	0.920	0.95
162_D	174_H	0.919	0.95
159_L	175_T	0.916	0.95
312_Y	318_L	0.915	0.95
66_I	71_I	0.915	0.95
222_A	227_V	0.914	0.95
305_N	313_E	0.914	0.95
119_V	205_C	0.913	0.95
681_K	685_D	0.911	0.95
570_Y	574_E	0.910	0.95
647_S	686_A	0.904	0.95
310_E	315_I	0.904	0.95
237_L	240_P	0.899	0.95
84_A	252_H	0.898	0.94
548_Q	552_D	0.897	0.94
318_L	321_I	0.893	0.94
62_L	66_I	0.891	0.94
247_L	457_V	0.890	0.94
53_E	487_A	0.890	0.94
33_Q	486_V	0.886	0.94
157_A	160_K	0.885	0.94
311_L	324_L	0.884	0.94
316_A	319_N	0.884	0.94
83_T	223_N	0.883	0.94
317_S	320_N	0.883	0.94
108_K	213_E	0.882	0.94
559_L	564_Q	0.881	0.94
278_L	282_L	0.880	0.94
230_A	240_P	0.880	0.94
230_A	234_E	0.879	0.94
403_W	406_A	0.875	0.94
652_Q	656_R	0.875	0.94
69_I	219_V	0.874	0.94
674_L	684_L	0.874	0.94
351_R	354_K	0.871	0.94
495_C	689_V	0.868	0.93
387_L	391_R	0.867	0.93
78_T	217_A	0.867	0.93
348_I	359_L	0.866	0.93
605_L	657_L	0.862	0.93
96_D	101_K	0.862	0.93
56_T	438_I	0.862	0.93
121_P	125_T	0.861	0.93
553_Y	557_L	0.861	0.93
258_R	262_E	0.859	0.93
463_R	468_F	0.858	0.93
189_T	193_S	0.857	0.93
225_A	260_A	0.857	0.93
422_R	431_L	0.857	0.93
530_E	558_R	0.856	0.93
521_M	611_H	0.855	0.93
595_A	651_I	0.855	0.93
533_K	606_S	0.854	0.93
659_R	663_C	0.853	0.93
303_R	312_Y	0.853	0.93
536_G	584_E	0.853	0.93
460_A	492_F	0.852	0.93
42_L	71_I	0.849	0.93
228_M	232_E	0.849	0.93
222_A	226_L	0.848	0.93
565_G	572_L	0.847	0.93
354_K	358_M	0.847	0.93
517_H	521_M	0.846	0.93
459_S	599_D	0.845	0.93
125_T	201_Y	0.844	0.92
127_L	132_P	0.843	0.92
267_I	273_R	0.841	0.92
473_E	635_R	0.840	0.92
110_T	210_A	0.837	0.92
476_G	479_E	0.837	0.92
488_L	601_K	0.837	0.92
421_T	432_W	0.836	0.92
314_L	321_I	0.834	0.92
536_G	607_Q	0.832	0.92
229_A	234_E	0.832	0.92
113_F	223_N	0.832	0.92
504_R	508_E	0.831	0.92
548_Q	566_D	0.831	0.92
313_E	325_Y	0.830	0.92
27_P	32_R	0.828	0.92
573_V	600_L	0.828	0.92
188_S	191_K	0.826	0.92
535_L	606_S	0.826	0.92
361_G	367_L	0.825	0.92
84_A	88_L	0.825	0.92
648_F	651_I	0.821	0.91
355_L	364_E	0.821	0.91
347_E	351_R	0.819	0.91
88_L	92_I	0.815	0.91
355_L	359_L	0.815	0.91
280_T	287_M	0.815	0.91
321_I	327_P	0.815	0.91
283_V	286_C	0.813	0.91
316_A	320_N	0.813	0.91
548_Q	563_V	0.813	0.91
313_E	317_S	0.810	0.91
348_I	354_K	0.809	0.91
337_A	340_E	0.809	0.91
39_A	45_E	0.808	0.91
255_D	433_F	0.805	0.91
323_N	327_P	0.803	0.90
85_N	614_A	0.803	0.90
348_I	352_L	0.800	0.90
412_S	418_K	0.799	0.90
591_L	595_A	0.798	0.90
538_L	608_V	0.798	0.90
383_H	387_L	0.798	0.90
308_C	318_L	0.798	0.90
158_K	162_D	0.796	0.90
538_L	653_Q	0.795	0.90
347_E	352_L	0.794	0.90
552_D	555_T	0.793	0.90
55_P	494_H	0.790	0.90
85_N	89_Q	0.789	0.90
353_A	357_E	0.788	0.90
46_E	484_R	0.787	0.90
568_P	571_R	0.786	0.90
449_W	455_I	0.785	0.89
97_L	101_K	0.782	0.89
300_I	315_I	0.782	0.89
564_Q	593_S	0.780	0.89
398_A	406_A	0.780	0.89
254_P	471_L	0.779	0.89
347_E	350_Q	0.778	0.89
631_K	636_Y	0.777	0.89
346_L	349_C	0.774	0.89
370_L	374_T	0.774	0.89
188_S	193_S	0.773	0.89
383_H	386_I	0.769	0.88
315_I	323_N	0.768	0.88
610_I	650_L	0.767	0.88
549_R	553_Y	0.767	0.88
526_R	530_E	0.765	0.88
188_S	194_C	0.764	0.88
360_R	364_E	0.762	0.88
41_T	49_H	0.762	0.88
153_Q	165_T	0.759	0.88
305_N	312_Y	0.758	0.88
308_C	322_L	0.758	0.88
266_E	269_A	0.758	0.88
181_D	185_R	0.756	0.88
282_L	286_C	0.756	0.88
114_G	223_N	0.756	0.88
160_K	163_L	0.755	0.88
226_L	230_A	0.755	0.88
64_Y	81_V	0.755	0.88
195_L	200_Y	0.754	0.88
397_E	400_S	0.751	0.87
189_T	195_L	0.750	0.87
598_L	658_I	0.749	0.87
36_A	40_K	0.749	0.87
300_I	303_R	0.747	0.87
304_L	312_Y	0.746	0.87
62_L	100_L	0.744	0.87
310_E	318_L	0.742	0.87
101_K	107_L	0.742	0.87
350_Q	354_K	0.741	0.87
61_T	65_L	0.740	0.87
572_L	575_L	0.740	0.87
349_C	352_L	0.739	0.86
616_P	627_G	0.739	0.86
224_H	230_A	0.739	0.86
361_G	366_F	0.738	0.86
34_M	488_L	0.738	0.86
474_M	626_E	0.738	0.86
400_S	403_W	0.736	0.86
318_L	325_Y	0.735	0.86
523_A	527_K	0.735	0.86
96_D	437_G	0.735	0.86
301_P	316_A	0.734	0.86
313_E	327_P	0.734	0.86
304_L	314_L	0.734	0.86
538_L	600_L	0.734	0.86
258_R	436_V	0.734	0.86
67_P	70_A	0.733	0.86
314_L	317_S	0.733	0.86
522_A	539_V	0.732	0.86
99_L	102_K	0.732	0.86
400_S	404_R	0.731	0.86
423_E	430_H	0.728	0.86
307_H	314_L	0.725	0.85
83_T	87_A	0.725	0.85
396_F	400_S	0.725	0.85
456_I	534_H	0.724	0.85
599_D	665_G	0.723	0.85
498_G	654_V	0.722	0.85
66_I	70_A	0.722	0.85
286_C	362_L	0.721	0.85
505_M	509_P	0.721	0.85
369_D	373_K	0.720	0.85
301_P	315_I	0.720	0.85
120_C	194_C	0.720	0.85
507_V	510_S	0.718	0.85
107_L	219_V	0.718	0.85
571_R	574_E	0.715	0.85
266_E	432_W	0.715	0.85
616_P	645_S	0.714	0.85
183_L	186_R	0.714	0.85
316_A	321_I	0.713	0.84
498_G	690_F	0.712	0.84
643_L	678_N	0.712	0.84
180_D	186_R	0.711	0.84
508_E	520_E	0.711	0.84
256_V	259_D	0.710	0.84
88_L	93_Y	0.710	0.84
358_M	362_L	0.710	0.84
209_V	213_E	0.710	0.84
641_Q	645_S	0.709	0.84
54_A	223_N	0.708	0.84
551_L	589_V	0.708	0.84
395_M	403_W	0.707	0.84
309_E	324_L	0.705	0.84
342_P	348_I	0.701	0.83
274_L	278_L	0.700	0.83
35_I	62_L	0.700	0.83
70_A	536_G	0.699	0.83
647_S	650_L	0.698	0.83
318_L	324_L	0.697	0.83
349_C	353_A	0.695	0.83
41_T	47_G	0.695	0.83
64_Y	224_H	0.691	0.83
526_R	554_V	0.689	0.82
515_E	519_A	0.688	0.82
542_A	595_A	0.688	0.82
646_A	683_L	0.688	0.82
307_H	316_A	0.687	0.82
229_A	232_E	0.687	0.82
602_G	660_S	0.686	0.82
102_K	106_D	0.685	0.82
273_R	312_Y	0.685	0.82
113_F	117_R	0.684	0.82
607_Q	666_E	0.683	0.82
249_E	656_R	0.683	0.82
303_R	306_A	0.683	0.82
623_V	627_G	0.682	0.82
359_L	374_T	0.682	0.82
35_I	39_A	0.681	0.82
249_E	652_Q	0.681	0.82
317_S	322_L	0.680	0.82
268_T	609_H	0.679	0.81
113_F	118_Y	0.679	0.81
88_L	113_F	0.679	0.81
564_Q	638_F	0.677	0.81
311_L	319_N	0.676	0.81
552_D	556_D	0.675	0.81
115_R	208_F	0.675	0.81
689_V	692_I	0.675	0.81
389_M	395_M	0.674	0.81
196_N	199_C	0.674	0.81
157_A	164_D	0.673	0.81
312_Y	320_N	0.673	0.81
112_A	226_L	0.672	0.81
256_V	544_G	0.671	0.81
320_N	323_N	0.671	0.81
249_E	659_R	0.671	0.81
115_R	207_F	0.669	0.80
460_A	564_Q	0.667	0.80
115_R	194_C	0.667	0.80
71_I	244_L	0.665	0.80
254_P	258_R	0.665	0.80
306_A	316_A	0.664	0.80
490_S	658_I	0.663	0.80
520_E	523_A	0.663	0.80
158_K	169_D	0.663	0.80
350_Q	353_A	0.661	0.80
500_I	674_L	0.659	0.79
213_E	217_A	0.659	0.79
98_P	194_C	0.658	0.79
461_T	659_R	0.657	0.79
249_E	655_G	0.657	0.79
301_P	312_Y	0.657	0.79
499_K	503_P	0.657	0.79
647_S	682_R	0.657	0.79
154_K	161_G	0.656	0.79
500_I	506_R	0.655	0.79
19_Q	25_F	0.654	0.79
335_R	342_P	0.653	0.79
500_I	509_P	0.652	0.79
576_H	586_S	0.652	0.79
80_V	399_Q	0.652	0.79
650_L	674_L	0.651	0.79
191_K	194_C	0.650	0.79
178_A	184_W	0.650	0.79
257_A	437_G	0.649	0.78
683_L	686_A	0.649	0.78
308_C	313_E	0.648	0.78
61_T	596_E	0.648	0.78
34_M	63_S	0.647	0.78
564_Q	591_L	0.646	0.78
114_G	492_F	0.645	0.78
91_Q	118_Y	0.645	0.78
312_Y	323_N	0.644	0.78
315_I	327_P	0.644	0.78
545_R	548_Q	0.644	0.78
109_F	219_V	0.644	0.78
345_V	349_C	0.643	0.78
119_V	167_K	0.642	0.78
65_L	92_I	0.641	0.78
261_L	443_Q	0.641	0.78
456_I	520_E	0.640	0.78
97_L	219_V	0.638	0.77
81_V	224_H	0.638	0.77
388_Q	395_M	0.637	0.77
158_K	161_G	0.636	0.77
464_S	647_S	0.636	0.77
653_Q	665_G	0.635	0.77
504_R	675_L	0.635	0.77
69_I	97_L	0.635	0.77
389_M	392_A	0.633	0.77
162_D	165_T	0.633	0.77
518_I	521_M	0.630	0.76
28_R	657_L	0.630	0.76
625_T	628_E	0.630	0.76
535_L	585_R	0.629	0.76
304_L	315_I	0.628	0.76
88_L	223_N	0.628	0.76
535_L	576_H	0.627	0.76
85_N	115_R	0.627	0.76
113_F	120_C	0.627	0.76
45_E	79_L	0.627	0.76
492_F	498_G	0.626	0.76
158_K	163_L	0.625	0.76
204_E	209_V	0.625	0.76
62_L	99_L	0.625	0.76
312_Y	324_L	0.624	0.76
354_K	361_G	0.624	0.76
363_A	368_N	0.624	0.76
529_V	533_K	0.620	0.75
42_L	454_H	0.620	0.75
311_L	320_N	0.619	0.75
559_L	587_V	0.618	0.75
356_T	361_G	0.617	0.75
524_F	527_K	0.617	0.75
53_E	651_I	0.615	0.75
98_P	101_K	0.615	0.75
338_M	341_L	0.615	0.75
342_P	345_V	0.615	0.75
38_V	52_I	0.614	0.75
91_Q	96_D	0.614	0.75
345_V	366_F	0.614	0.75
280_T	283_V	0.614	0.75
155_R	164_D	0.613	0.74
630_L	640_V	0.613	0.74
553_Y	556_D	0.612	0.74
559_L	606_S	0.611	0.74
314_L	322_L	0.611	0.74
82_S	227_V	0.610	0.74
53_E	91_Q	0.608	0.74
201_Y	204_E	0.608	0.74
254_P	449_W	0.608	0.74
356_T	365_L	0.607	0.74
355_L	367_L	0.607	0.74
112_A	222_A	0.606	0.74
25_F	613_I	0.606	0.74
86_V	93_Y	0.606	0.74
343_D	346_L	0.606	0.74
88_L	120_C	0.606	0.74
343_D	350_Q	0.605	0.73
24_D	28_R	0.604	0.73
312_Y	321_I	0.604	0.73
167_K	174_H	0.604	0.73
309_E	315_I	0.603	0.73
388_Q	392_A	0.603	0.73
444_L	475_S	0.602	0.73
601_K	683_L	0.601	0.73
208_F	536_G	0.601	0.73
112_A	649_N	0.601	0.73
360_R	367_L	0.601	0.73
436_V	622_V	0.601	0.73
118_Y	590_G	0.600	0.73
387_L	394_G	0.599	0.73
394_G	397_E	0.598	0.73
70_A	245_L	0.598	0.73
390_N	393_L	0.598	0.73
348_I	366_F	0.597	0.72
42_L	68_G	0.596	0.72
565_G	569_R	0.596	0.72
654_V	690_F	0.595	0.72
394_G	403_W	0.595	0.72
355_L	365_L	0.595	0.72
648_F	658_I	0.595	0.72
469_S	473_E	0.594	0.72
399_Q	405_L	0.594	0.72
123_N	126_A	0.593	0.72
65_L	653_Q	0.593	0.72
371_S	374_T	0.592	0.72
518_I	546_A	0.592	0.72
35_I	67_P	0.591	0.72
393_L	397_E	0.591	0.72
153_Q	157_A	0.591	0.72
307_H	313_E	0.591	0.72
190_D	195_L	0.590	0.72
63_S	72_A	0.590	0.72
157_A	161_G	0.588	0.71
84_A	87_A	0.587	0.71
28_R	605_L	0.587	0.71
225_A	256_V	0.587	0.71
58_V	468_F	0.586	0.71
301_P	310_E	0.584	0.71
528_Q	670_Y	0.584	0.71
56_T	85_N	0.584	0.71
363_A	367_L	0.584	0.71
317_S	321_I	0.583	0.71
38_V	127_L	0.582	0.71
384_R	387_L	0.582	0.71
498_G	667_V	0.581	0.70
536_G	600_L	0.580	0.70
313_E	318_L	0.580	0.70
25_F	32_R	0.579	0.70
619_D	624_I	0.579	0.70
226_L	229_A	0.578	0.70
249_E	597_G	0.578	0.70
391_R	394_G	0.578	0.70
156_C	161_G	0.577	0.70
345_V	354_K	0.574	0.70
474_M	554_V	0.574	0.70
417_T	625_T	0.574	0.70
321_I	326_M	0.572	0.69
87_A	91_Q	0.572	0.69
415_P	419_W	0.569	0.69
54_A	58_V	0.569	0.69
45_E	71_I	0.569	0.69
498_G	506_R	0.569	0.69
339_G	343_D	0.569	0.69
538_L	590_G	0.569	0.69
30_P	58_V	0.568	0.69
154_K	164_D	0.568	0.69
55_P	64_Y	0.567	0.69
344_E	351_R	0.567	0.69
189_T	192_A	0.565	0.68
356_T	367_L	0.565	0.68
597_G	659_R	0.565	0.68
90_D	193_S	0.563	0.68
346_L	366_F	0.562	0.68
280_T	285_T	0.562	0.68
162_D	170_G	0.562	0.68
311_L	327_P	0.561	0.68
401_K	405_L	0.561	0.68
38_V	458_T	0.561	0.68
501_V	506_R	0.560	0.68
576_H	604_L	0.559	0.68
316_A	325_Y	0.559	0.68
206_P	595_A	0.559	0.68
209_V	548_Q	0.558	0.67
169_D	173_D	0.557	0.67
276_L	309_E	0.556	0.67
46_E	49_H	0.556	0.67
207_F	211_R	0.555	0.67
536_G	664_W	0.555	0.67
307_H	310_E	0.554	0.67
351_R	355_L	0.553	0.67
278_L	281_K	0.553	0.67
120_C	540_L	0.552	0.67
86_V	223_N	0.552	0.67
597_G	655_G	0.552	0.67
114_G	117_R	0.552	0.67
527_K	531_S	0.551	0.66
304_L	308_C	0.549	0.66
305_N	316_A	0.549	0.66
551_L	566_D	0.548	0.66
503_P	507_V	0.548	0.66
315_I	319_N	0.548	0.66
474_M	477_L	0.547	0.66
35_I	38_V	0.547	0.66
117_R	223_N	0.547	0.66
386_I	393_L	0.547	0.66
468_F	476_G	0.546	0.66
224_H	540_L	0.543	0.65
500_I	615_F	0.543	0.65
223_N	615_F	0.543	0.65
361_G	365_L	0.542	0.65
340_E	343_D	0.542	0.65
84_A	96_D	0.542	0.65
461_T	597_G	0.542	0.65
309_E	320_N	0.541	0.65
677_K	681_K	0.541	0.65
613_I	621_P	0.541	0.65
235_A	239_D	0.541	0.65
114_G	214_I	0.539	0.65
190_D	194_C	0.539	0.65
397_E	401_K	0.539	0.65
88_L	540_L	0.537	0.64
437_G	440_V	0.537	0.64
112_A	211_R	0.536	0.64
165_T	246_V	0.535	0.64
301_P	305_N	0.535	0.64
315_I	324_L	0.535	0.64
519_A	549_R	0.535	0.64
393_L	396_F	0.535	0.64
190_D	193_S	0.534	0.64
64_Y	89_Q	0.534	0.64
124_L	127_L	0.533	0.64
100_L	105_P	0.533	0.64
251_H	461_T	0.532	0.64
675_L	678_N	0.530	0.63
312_Y	327_P	0.530	0.63
51_A	645_S	0.529	0.63
117_R	576_H	0.529	0.63
249_E	461_T	0.528	0.63
33_Q	488_L	0.528	0.63
407_S	412_S	0.528	0.63
307_H	326_M	0.528	0.63
626_E	641_Q	0.526	0.63
644_P	682_R	0.526	0.63
363_A	366_F	0.526	0.63
345_V	352_L	0.525	0.63
201_Y	548_Q	0.525	0.63
89_Q	92_I	0.524	0.63
613_I	644_P	0.523	0.62
634_N	638_F	0.523	0.62
124_L	608_V	0.523	0.62
565_G	568_P	0.522	0.62
352_L	359_L	0.522	0.62
461_T	655_G	0.522	0.62
64_Y	88_L	0.522	0.62
497_Q	664_W	0.522	0.62
54_A	88_L	0.522	0.62
89_Q	113_F	0.522	0.62
268_T	430_H	0.522	0.62
29_A	32_R	0.521	0.62
503_P	524_F	0.521	0.62
443_Q	447_L	0.521	0.62
398_A	402_L	0.520	0.62
286_C	289_Q	0.520	0.62
248_D	652_Q	0.520	0.62
500_I	505_M	0.519	0.62
364_E	368_N	0.519	0.62
646_A	665_G	0.519	0.62
273_R	414_A	0.518	0.62
669_I	687_L	0.518	0.62
56_T	646_A	0.517	0.62
84_A	596_E	0.517	0.62
386_I	390_N	0.517	0.62
113_F	657_L	0.517	0.62
85_N	92_I	0.516	0.61
355_L	363_A	0.516	0.61
90_D	570_Y	0.515	0.61
20_E	23_P	0.514	0.61
600_L	606_S	0.514	0.61
274_L	280_T	0.514	0.61
306_A	423_E	0.514	0.61
498_G	687_L	0.513	0.61
101_K	106_D	0.513	0.61
304_L	313_E	0.513	0.61
672_K	676_T	0.513	0.61
560_M	585_R	0.513	0.61
365_L	371_S	0.513	0.61
354_K	367_L	0.512	0.61
35_I	100_L	0.512	0.61
300_I	312_Y	0.512	0.61
509_P	672_K	0.512	0.61
41_T	345_V	0.511	0.61
301_P	308_C	0.511	0.61
365_L	369_D	0.511	0.61
385_L	390_N	0.510	0.61
155_R	162_D	0.510	0.61
53_E	665_G	0.509	0.60
309_E	322_L	0.509	0.60
336_F	343_D	0.509	0.60
548_Q	633_L	0.509	0.60
285_T	288_E	0.509	0.60
63_S	81_V	0.509	0.60
232_E	592_Q	0.509	0.60
314_L	326_M	0.509	0.60
343_D	347_E	0.507	0.60
398_A	403_W	0.506	0.60
226_L	626_E	0.506	0.60
472_Q	475_S	0.505	0.60
405_L	409_A	0.505	0.60
464_S	612_K	0.505	0.60
56_T	59_G	0.505	0.60
368_N	410_Q	0.504	0.60
42_L	246_V	0.504	0.60
558_R	585_R	0.503	0.59
575_L	582_N	0.503	0.59
550_F	563_V	0.503	0.59
348_I	371_S	0.501	0.59
356_T	364_E	0.501	0.59
112_A	210_A	0.501	0.59
304_L	321_I	0.501	0.59
387_L	390_N	0.500	0.59
313_E	324_L	0.500	0.59

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4a15A	1	0.8073	100	0.349	Contact Map
3crvA	1	0.7556	100	0.393	Contact Map
2vl7A	1	0.6299	100	0.438	Contact Map
1gkuB	1	0.5573	100	0.77	Contact Map
4ys0A	1	0.7696	100	0.784	Contact Map
4dduA	1	0.5936	100	0.797	Contact Map
3fhoA	2	0.419	100	0.803	Contact Map
2ykgA	1	0.6634	100	0.805	Contact Map
3oiyA	1	0.5503	100	0.808	Contact Map
4a2qA	1	0.6453	100	0.81	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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