GREMLIN Database
SCPA - Methylmalonyl-CoA mutase
UniProt: P27253 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11444
Length: 714 (677)
Sequences: 1424 (425)
Seq/√Len: 16.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
256_I301_V6.5471.00
134_T488_I4.7281.00
299_E410_R4.7041.00
681_A685_E4.3541.00
494_D498_T4.3371.00
172_E523_R4.1831.00
505_T537_V3.9881.00
265_K268_D3.7891.00
169_V523_R3.7531.00
177_T180_K3.5171.00
245_V405_I3.4790.99
516_A520_N3.4620.99
257_K417_D3.3620.99
652_I671_A3.3330.99
284_F398_I3.3180.99
629_R633_E3.3150.99
139_K173_E3.3140.99
410_R414_Q3.3040.99
36_K43_D3.1880.99
408_Q411_A3.1490.99
334_V357_F3.1320.99
167_Y171_A3.1210.99
148_D180_K3.0920.99
277_F290_L3.0620.99
116_S133_D3.0480.99
161_L535_L2.9870.98
284_F397_Y2.9590.98
493_D496_A2.9560.98
217_C226_T2.9250.98
658_A661_K2.9210.98
166_F528_L2.9170.98
295_Y406_V2.9160.98
116_S131_A2.8860.98
229_I273_L2.8570.98
240_N438_A2.8470.98
479_N483_A2.8220.98
148_D176_V2.8070.98
573_Q707_N2.7870.97
487_R491_T2.7820.97
504_L535_L2.7490.97
604_I701_S2.7440.97
442_E451_R2.7320.97
461_L464_E2.7100.97
445_L451_R2.6900.97
625_E658_A2.6570.96
247_F430_L2.6560.96
87_S91_Y2.6370.96
535_L539_F2.5890.96
85_K480_E2.5820.96
331_Y357_F2.5620.96
178_P216_W2.5560.96
201_Y532_S2.5550.96
604_I608_Y2.4660.95
277_F318_C2.3950.94
506_H509_Q2.3940.94
452_V458_K2.3690.93
140_V484_S2.2910.92
422_M431_P2.2710.92
302_S312_L2.2650.92
403_D407_K2.2600.92
260_I266_I2.2580.92
267_D311_S2.2220.91
27_H35_I2.2120.91
178_P220_N2.2080.91
586_R635_D2.1990.90
215_A262_A2.1570.89
265_K307_Q2.1540.89
139_K525_R2.1530.89
548_C617_L2.1290.89
136_E139_K2.1200.89
303_G417_D2.1120.88
361_L677_P2.1080.88
93_R366_D2.1080.88
104_V132_I2.1010.88
497_V526_A2.1010.88
151_S182_T2.0930.88
495_A499_A2.0690.87
482_I486_E2.0680.87
400_S404_Q2.0600.87
346_L392_L2.0490.87
508_A535_L2.0090.86
483_A487_R1.9790.85
656_V688_V1.9710.85
214_I259_A1.9610.84
204_K427_E1.9610.84
370_R374_N1.9580.84
30_A445_L1.9500.84
335_I338_T1.9470.84
211_A258_A1.9400.84
341_A352_L1.9300.83
498_T502_N1.9110.83
60_V295_Y1.9020.82
166_F522_A1.9010.82
414_Q418_E1.8980.82
649_K682_F1.8870.82
639_V655_L1.8840.82
36_K39_Y1.8780.82
638_V670_V1.8700.81
135_V139_K1.8600.81
575_E584_R1.8550.81
345_T385_L1.8490.81
424_K427_E1.8470.80
656_V669_V1.8450.80
172_E178_P1.7980.79
391_P398_I1.7920.78
298_S302_S1.7790.78
522_A531_I1.7770.78
31_E285_M1.7750.78
503_A520_N1.7730.78
604_I670_V1.7650.77
507_A517_A1.7350.76
656_V686_R1.7310.76
301_V306_A1.7290.76
307_Q311_S1.7200.75
684_Q691_I1.7160.75
365_T368_S1.6940.74
404_Q408_Q1.6880.74
40_T43_D1.6800.74
671_A688_V1.6780.73
489_R497_V1.6740.73
210_I214_I1.6680.73
173_E525_R1.6670.73
161_L518_A1.6570.73
277_F293_A1.6510.72
584_R616_D1.6500.72
616_D635_D1.6360.72
658_A662_W1.6320.71
381_E459_Y1.6280.71
178_P519_V1.6200.71
616_D634_N1.6180.71
496_A520_N1.6170.71
584_R637_H1.6150.71
168_I519_V1.5960.70
632_V662_W1.5950.70
257_K304_F1.5920.69
136_E525_R1.5900.69
502_N506_H1.5880.69
471_E649_K1.5720.68
116_S481_Q1.5640.68
78_Y196_R1.5520.67
586_R616_D1.5500.67
135_V525_R1.5440.67
254_E257_K1.5370.67
168_I216_W1.5360.67
249_L300_A1.5310.66
503_A517_A1.5290.66
489_R527_T1.5280.66
199_Y544_V1.5080.65
92_R144_Q1.5010.65
242_V405_I1.4940.64
507_A510_H1.4810.64
89_A93_R1.4800.64
244_Q289_M1.4640.63
243_Q412_I1.4610.62
570_I699_L1.4560.62
669_V688_V1.4460.62
253_I300_A1.4420.61
39_Y400_S1.4350.61
682_F686_R1.4350.61
625_E654_E1.4340.61
136_E488_I1.4340.61
489_R504_L1.4270.61
254_E258_A1.4220.60
26_V34_A1.4210.60
496_A500_A1.4110.60
505_T509_Q1.4100.60
100_K149_K1.4100.60
629_R658_A1.4080.60
589_I604_I1.4070.59
507_A512_E1.3970.59
692_Y704_D1.3950.59
240_N243_Q1.3870.58
253_I305_G1.3750.58
570_I703_R1.3740.58
111_H196_R1.3700.57
349_T352_L1.3690.57
327_E649_K1.3670.57
214_I262_A1.3650.57
210_I262_A1.3620.57
641_A652_I1.3590.57
331_Y335_I1.3420.56
479_N486_E1.3410.56
616_D630_L1.3340.55
249_L252_G1.3310.55
338_T348_G1.3190.54
416_I578_L1.3120.54
339_I343_A1.3110.54
500_A524_V1.3080.54
608_Y701_S1.2980.53
507_A539_F1.2940.53
572_A576_Q1.2930.53
52_T60_V1.2900.53
437_E441_R1.2810.52
298_S312_L1.2810.52
330_P601_A1.2760.52
629_R662_W1.2720.52
678_Q691_I1.2710.52
33_I285_M1.2700.52
588_L639_V1.2650.51
331_Y371_I1.2630.51
53_L56_L1.2600.51
412_I430_L1.2590.51
346_L385_L1.2580.51
179_D220_N1.2570.51
185_I226_T1.2570.51
270_A311_S1.2540.51
504_L517_A1.2510.50
518_A531_I1.2480.50
54_P283_L1.2440.50
331_Y367_F1.2440.50
433_R549_V1.2430.50
28_Q34_A1.2320.49
660_K665_E1.2290.49
590_A627_I1.2270.49
318_C349_T1.2250.49
78_Y111_H1.2220.49
241_C278_G1.2200.49
628_A658_A1.2190.49
38_L389_V1.2160.48
504_L521_A1.2160.48
327_E601_A1.2150.48
592_M655_L1.2130.48
392_L398_I1.2110.48
680_Y693_G1.2090.48
178_P523_R1.2060.48
606_S609_S1.2020.48
521_A526_A1.1990.47
614_D634_N1.1930.47
244_Q286_N1.1820.46
494_D497_V1.1690.46
409_A413_I1.1680.46
533_D537_V1.1670.46
267_D270_A1.1660.46
657_E661_K1.1660.46
64_R259_A1.1550.45
215_A219_G1.1530.45
573_Q703_R1.1510.45
496_A524_V1.1500.45
469_V678_Q1.1470.44
128_A197_N1.1340.44
283_L287_V1.1300.43
229_I256_I1.1270.43
250_A413_I1.1220.43
604_I638_V1.1210.43
241_C405_I1.1200.43
338_T383_S1.1190.43
446_I453_I1.1160.43
111_H197_N1.1150.43
356_A369_A1.1130.42
42_A45_D1.1070.42
253_I306_A1.1050.42
483_A490_A1.1030.42
345_T379_I1.1020.42
35_I397_Y1.0950.41
486_E579_A1.0940.41
341_A379_I1.0940.41
486_E489_R1.0920.41
243_Q392_L1.0920.41
282_D387_R1.0910.41
99_Q102_L1.0880.41
568_D689_A1.0880.41
485_L488_I1.0800.41
25_L37_P1.0780.40
357_F367_F1.0770.40
584_R630_L1.0710.40
135_V268_D1.0670.40
490_A495_A1.0670.40
242_V412_I1.0580.39
93_R96_A1.0540.39
85_K89_A1.0530.39
567_F570_I1.0530.39
168_I221_M1.0520.39
361_L467_T1.0490.39
284_F391_P1.0490.39
486_E490_A1.0470.39
149_K180_K1.0450.39
243_Q323_W1.0450.39
484_S539_F1.0450.39
119_P625_E1.0410.38
75_I373_R1.0410.38
346_L397_Y1.0360.38
592_M627_I1.0330.38
267_D307_Q1.0280.38
630_L634_N1.0280.38
208_R539_F1.0280.38
281_M340_E1.0260.38
285_M397_Y1.0220.37
680_Y691_I1.0180.37
589_I608_Y1.0160.37
243_Q434_M1.0150.37
135_V488_I1.0140.37
219_G509_Q1.0080.37
257_K261_S1.0010.36
536_E541_R1.0000.36
652_I688_V1.0000.36
271_P300_A0.9990.36
178_P520_N0.9990.36
300_A410_R0.9990.36
253_I303_G0.9950.36
171_A523_R0.9940.36
64_R448_Q0.9940.36
588_L636_V0.9930.36
434_M437_E0.9910.36
197_N324_S0.9890.36
411_A414_Q0.9890.36
78_Y108_L0.9890.36
323_W446_I0.9870.35
64_R243_Q0.9840.35
111_H128_A0.9820.35
490_A499_A0.9810.35
499_A503_A0.9810.35
234_M701_S0.9780.35
242_V348_G0.9780.35
416_I628_A0.9740.35
118_N533_D0.9720.35
392_L397_Y0.9670.34
570_I573_Q0.9670.34
547_Q606_S0.9650.34
176_V180_K0.9630.34
584_R614_D0.9600.34
641_A671_A0.9600.34
323_W392_L0.9590.34
570_I574_T0.9570.34
296_L300_A0.9560.34
616_D637_H0.9540.34
44_L47_L0.9530.34
214_I269_F0.9530.34
25_L34_A0.9530.34
388_T393_A0.9520.34
478_R482_I0.9500.33
256_I484_S0.9490.33
703_R707_N0.9460.33
256_I266_I0.9450.33
649_K656_V0.9440.33
548_C634_N0.9420.33
215_A218_S0.9410.33
161_L539_F0.9410.33
299_E414_Q0.9400.33
664_R667_I0.9360.33
75_I377_I0.9340.33
251_D422_M0.9300.32
54_P60_V0.9280.32
577_F581_N0.9280.32
339_I379_I0.9250.32
210_I227_I0.9230.32
495_A498_T0.9230.32
485_L489_R0.9210.32
136_E318_C0.9210.32
604_I640_G0.9210.32
214_I227_I0.9200.32
440_A633_E0.9200.32
266_I304_F0.9190.32
164_L224_F0.9190.32
641_A655_L0.9180.32
681_A684_Q0.9170.32
52_T295_Y0.9160.32
571_V580_D0.9140.32
213_I258_A0.9130.32
167_Y569_A0.9110.31
542_Y545_P0.9090.31
59_Y307_Q0.9090.31
668_C689_A0.9080.31
330_P442_E0.9070.31
568_D686_R0.9070.31
168_I178_P0.9050.31
472_I477_V0.9040.31
247_F412_I0.9040.31
46_N50_T0.9040.31
39_Y43_D0.9030.31
211_A262_A0.9030.31
485_L527_T0.9030.31
270_A301_V0.9030.31
94_N99_Q0.9020.31
361_L484_S0.8960.31
295_Y298_S0.8960.31
490_A496_A0.8930.31
299_E302_S0.8900.30
413_I417_D0.8890.30
287_V690_A0.8890.30
128_A198_T0.8810.30
32_G54_P0.8800.30
100_K398_I0.8780.30
335_I378_I0.8760.30
638_V705_V0.8750.30
504_L508_A0.8750.30
377_I423_A0.8730.30
543_L546_S0.8730.30
587_I688_V0.8730.30
567_F611_L0.8700.29
78_Y198_T0.8700.29
586_R614_D0.8670.29
122_A654_E0.8670.29
384_E546_S0.8660.29
498_T685_E0.8640.29
182_T223_R0.8640.29
588_L627_I0.8610.29
568_D700_D0.8600.29
66_T485_L0.8600.29
100_K240_N0.8590.29
583_R635_D0.8570.29
361_L601_A0.8510.29
583_R633_E0.8500.28
518_A522_A0.8480.28
84_A95_L0.8480.28
480_E483_A0.8470.28
254_E423_A0.8450.28
604_I698_M0.8450.28
64_R392_L0.8450.28
85_K519_V0.8440.28
361_L574_T0.8420.28
489_R529_G0.8410.28
399_E402_T0.8400.28
166_F471_E0.8400.28
491_T509_Q0.8390.28
261_S498_T0.8390.28
161_L167_Y0.8380.28
54_P293_A0.8370.28
601_A705_V0.8340.28
569_A703_R0.8330.28
100_K150_M0.8330.28
258_A261_S0.8310.28
503_A512_E0.8310.28
36_K400_S0.8300.28
326_T330_P0.8300.28
173_E523_R0.8250.27
548_C633_E0.8240.27
285_M329_D0.8210.27
95_L426_I0.8210.27
171_A519_V0.8190.27
339_I342_L0.8180.27
568_D572_A0.8170.27
100_K397_Y0.8170.27
189_I201_Y0.8160.27
284_F346_L0.8150.27
94_N150_M0.8150.27
143_D265_K0.8140.27
638_V668_C0.8130.27
345_T588_L0.8120.27
252_G422_M0.8120.27
406_V410_R0.8080.27
277_F316_T0.8070.26
546_S549_V0.8060.26
243_Q426_I0.8060.26
79_A91_Y0.8060.26
329_D371_I0.8050.26
386_C701_S0.8040.26
242_V408_Q0.8040.26
38_L53_L0.8030.26
442_E601_A0.8020.26
338_T378_I0.8010.26
78_Y128_A0.8000.26
483_A533_D0.7990.26
346_L656_V0.7980.26
134_T485_L0.7960.26
27_H387_R0.7960.26
519_V522_A0.7950.26
385_L601_A0.7950.26
632_V639_V0.7900.26
592_M643_S0.7900.26
25_L53_L0.7900.26
172_E176_V0.7900.26
266_I287_V0.7900.26
564_A567_F0.7890.26
324_S340_E0.7890.26
241_C287_V0.7890.26
179_D302_S0.7880.26
568_D571_V0.7860.26
618_S622_S0.7860.26
108_L196_R0.7840.25
330_P656_V0.7840.25
616_D636_V0.7840.25
201_Y405_I0.7830.25
185_I210_I0.7810.25
116_S485_L0.7800.25
166_F406_V0.7790.25
407_K411_A0.7790.25
243_Q283_L0.7780.25
42_A51_G0.7770.25
284_F392_L0.7750.25
226_T368_S0.7750.25
49_V60_V0.7740.25
656_V690_A0.7740.25
225_N272_R0.7730.25
78_Y105_A0.7730.25
361_L410_R0.7720.25
136_E542_Y0.7710.25
589_I638_V0.7710.25
245_V409_A0.7670.25
44_L50_T0.7670.25
327_E442_E0.7640.25
569_A700_D0.7630.25
60_V69_T0.7630.25
38_L404_Q0.7630.25
505_T534_A0.7610.24
342_L346_L0.7590.24
223_R482_I0.7580.24
486_E632_V0.7570.24
260_I306_A0.7560.24
247_F428_A0.7560.24
479_N487_R0.7560.24
148_D177_T0.7550.24
483_A495_A0.7540.24
258_A686_R0.7530.24
450_K589_I0.7530.24
265_K500_A0.7530.24
65_A484_S0.7520.24
295_Y410_R0.7520.24
144_Q216_W0.7500.24
242_V426_I0.7480.24
571_V575_E0.7470.24
324_S337_T0.7470.24
490_A575_E0.7470.24
253_I304_F0.7470.24
224_F519_V0.7460.24
288_A401_L0.7450.24
240_N397_Y0.7420.24
171_A178_P0.7420.24
418_E576_Q0.7420.24
576_Q580_D0.7410.24
450_K567_F0.7410.24
213_I259_A0.7400.24
278_G290_L0.7390.23
335_I570_I0.7390.23
286_N289_M0.7380.23
601_A656_V0.7370.23
317_H353_H0.7370.23
190_L422_M0.7350.23
493_D625_E0.7350.23
426_I434_M0.7340.23
167_Y310_K0.7340.23
29_T39_Y0.7330.23
357_F467_T0.7310.23
554_A592_M0.7310.23
277_F664_R0.7310.23
208_R507_A0.7300.23
370_R461_L0.7290.23
295_Y403_D0.7290.23
300_A303_G0.7290.23
496_A692_Y0.7280.23
337_T340_E0.7280.23
29_T285_M0.7270.23
29_T33_I0.7260.23
49_V54_P0.7250.23
235_G356_A0.7240.23
139_K649_K0.7220.23
356_A535_L0.7210.23
108_L199_Y0.7200.23
166_F451_R0.7190.23
204_K424_K0.7190.23
140_V144_Q0.7190.23
412_I416_I0.7190.23
142_F173_E0.7170.23
134_T235_G0.7160.23
104_V182_T0.7160.23
442_E488_I0.7160.23
308_D689_A0.7150.22
42_A386_C0.7140.22
89_A96_A0.7140.22
119_P639_V0.7130.22
704_D708_L0.7110.22
242_V378_I0.7100.22
616_D629_R0.7090.22
108_L111_H0.7090.22
170_A174_Q0.7080.22
393_A398_I0.7060.22
269_F273_L0.7060.22
193_Y264_L0.7060.22
105_A363_L0.7050.22
696_T701_S0.7050.22
134_T489_R0.7040.22
385_L489_R0.7040.22
261_S483_A0.7030.22
564_A568_D0.7030.22
579_A685_E0.7010.22
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226_T259_A0.7000.22
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337_T355_N0.6960.22
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494_D661_K0.6940.22
410_R413_I0.6920.22
627_I639_V0.6920.22
162_P532_S0.6920.22
187_N206_S0.6920.22
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285_M405_I0.6910.22
497_V524_V0.6890.21
309_P502_N0.6880.21
36_K40_T0.6870.21
197_N431_P0.6870.21
362_G365_T0.6870.21
271_P415_Q0.6860.21
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601_A688_V0.6840.21
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300_A449_G0.6840.21
400_S403_D0.6820.21
166_F531_I0.6820.21
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414_Q482_I0.6810.21
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393_A691_I0.6290.19
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496_A565_S0.6270.19
208_R218_S0.6260.19
259_A262_A0.6250.19
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185_I214_I0.6140.19
219_G407_K0.6140.19
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339_I416_I0.5690.17
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235_G278_G0.5610.17
199_Y539_F0.5600.17
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407_K450_K0.5570.17
197_N541_R0.5570.17
29_T393_A0.5560.17
73_W98_G0.5550.17
686_R691_I0.5550.17
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305_G630_L0.5540.17
628_A632_V0.5540.17
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348_G697_P0.5530.17
149_K504_L0.5530.17
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40_T543_L0.5500.16
125_V477_V0.5500.16
614_D630_L0.5500.16
547_Q550_T0.5490.16
662_W665_E0.5490.16
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191_K233_H0.5480.16
219_G506_H0.5470.16
258_A669_V0.5460.16
327_E361_L0.5460.16
61_R393_A0.5460.16
432_K436_E0.5460.16
213_I262_A0.5450.16
345_T383_S0.5450.16
414_Q417_D0.5450.16
287_V423_A0.5440.16
510_H514_L0.5430.16
253_I475_V0.5430.16
448_Q554_A0.5430.16
329_D464_E0.5430.16
575_E578_L0.5420.16
256_I335_I0.5420.16
466_E641_A0.5420.16
87_S94_N0.5420.16
172_E520_N0.5410.16
678_Q686_R0.5410.16
128_A196_R0.5410.16
253_I298_S0.5410.16
406_V552_V0.5410.16
199_Y224_F0.5400.16
500_A503_A0.5400.16
479_N498_T0.5400.16
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458_K699_L0.5400.16
224_F438_A0.5390.16
240_N362_G0.5390.16
306_A311_S0.5380.16
112_R128_A0.5380.16
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302_S305_G0.5370.16
256_I260_I0.5360.16
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148_D178_P0.5350.16
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301_V570_I0.5280.16
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45_D498_T0.5280.16
404_Q448_Q0.5270.16
245_V289_M0.5270.16
57_P567_F0.5270.16
357_F431_P0.5270.16
419_A428_A0.5270.16
86_E622_S0.5260.16
671_A686_R0.5260.16
299_E424_K0.5260.16
604_I644_L0.5250.16
47_L459_Y0.5250.16
381_E416_I0.5250.16
40_T119_P0.5240.16
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511_N685_E0.5240.16
224_F644_L0.5240.16
423_A503_A0.5230.16
381_E385_L0.5230.16
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570_I587_I0.5220.16
488_I491_T0.5220.16
219_G516_A0.5210.16
78_Y87_S0.5200.16
276_F319_Q0.5200.16
265_K309_P0.5200.16
166_F649_K0.5200.16
407_K480_E0.5190.15
92_R475_V0.5190.15
266_I301_V0.5190.15
632_V664_R0.5180.15
348_G378_I0.5180.15
567_F705_V0.5170.15
29_T387_R0.5170.15
214_I664_R0.5170.15
268_D471_E0.5170.15
500_A520_N0.5160.15
346_L601_A0.5160.15
550_T576_Q0.5160.15
210_I284_F0.5160.15
412_I688_V0.5160.15
407_K410_R0.5160.15
408_Q430_L0.5160.15
176_V519_V0.5150.15
519_V641_A0.5150.15
332_N378_I0.5150.15
116_S125_V0.5140.15
688_V698_M0.5130.15
153_S184_T0.5130.15
220_N405_I0.5130.15
334_V503_A0.5130.15
601_A677_P0.5130.15
407_K537_V0.5120.15
214_I323_W0.5120.15
404_Q407_K0.5120.15
601_A693_G0.5110.15
189_I193_Y0.5110.15
177_T543_L0.5110.15
253_I413_I0.5110.15
210_I223_R0.5100.15
486_E516_A0.5100.15
579_A684_Q0.5100.15
38_L41_E0.5090.15
652_I655_L0.5090.15
388_T574_T0.5090.15
249_L299_E0.5090.15
583_R616_D0.5080.15
256_I607_A0.5080.15
198_T544_V0.5080.15
296_L490_A0.5070.15
277_F430_L0.5070.15
241_C285_M0.5070.15
589_I617_L0.5060.15
301_V392_L0.5060.15
99_Q342_L0.5060.15
134_T525_R0.5060.15
571_V689_A0.5050.15
367_F371_I0.5050.15
241_C286_N0.5050.15
414_Q568_D0.5040.15
236_E276_F0.5040.15
342_L385_L0.5040.15
330_P705_V0.5030.15
92_R504_L0.5030.15
549_V576_Q0.5030.15
130_V141_L0.5030.15
633_E662_W0.5030.15
339_I452_V0.5030.15
300_A414_Q0.5020.15
229_I653_P0.5020.15
571_V574_T0.5020.15
43_D47_L0.5010.15
60_V410_R0.5010.15
570_I611_L0.5010.15
461_L686_R0.5010.15
242_V283_L0.5010.15
389_V526_A0.5010.15
109_A515_L0.5000.15
47_L52_T0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2xijA 2 0.9888 100 0.197 Contact Map
1reqA 1 0.986 100 0.2 Contact Map
4r3uA 2 0.7591 100 0.309 Contact Map
1reqB 1 0.8319 100 0.34 Contact Map
4xc8A 2 0.7479 100 0.35 Contact Map
3kp1A 2 0.8922 100 0.528 Contact Map
1ccwB 2 0.6246 100 0.847 Contact Map
3bulA 1 0.3039 99.9 0.923 Contact Map
4r3uC 1 0.1835 99.9 0.929 Contact Map
3ezxA 2 0.2857 99.9 0.929 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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