GREMLIN Database
FTSP - Cell division protein FtsP
UniProt: P26648 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11376
Length: 470 (404)
Sequences: 6456 (4508)
Seq/√Len: 224.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
80_R164_E5.1431.00
88_K129_V4.4521.00
51_T94_R4.0341.00
86_D129_V4.0161.00
49_F90_I3.8991.00
277_E421_K3.7301.00
90_I127_A3.5681.00
49_F92_S3.2981.00
55_A69_G3.1551.00
233_L281_I3.0661.00
424_V432_L2.9881.00
78_T160_M2.9791.00
92_S125_D2.8911.00
47_P88_K2.7791.00
91_Y120_M2.7581.00
251_P267_S2.6181.00
273_L279_R2.6181.00
256_S280_E2.5831.00
388_V396_F2.5431.00
387_T433_L2.4971.00
160_M234_L2.4601.00
57_W67_V2.4471.00
233_L244_L2.4291.00
388_V434_V2.3651.00
56_H66_S2.2861.00
56_H64_R2.2851.00
252_L281_I2.2741.00
354_R358_L2.2341.00
407_N433_L2.2111.00
379_Q382_T2.1981.00
141_Y159_G2.1701.00
121_S124_A2.1651.00
54_R66_S2.1621.00
385_R406_R2.1091.00
83_K165_D2.0801.00
47_P90_I2.0771.00
385_R435_Y2.0691.00
160_M185_I2.0591.00
427_D430_V2.0581.00
251_P269_K2.0581.00
185_I236_A2.0171.00
51_T92_S2.0111.00
112_L126_W2.0021.00
241_R425_W1.9841.00
231_L281_I1.9581.00
224_V285_M1.9241.00
53_Q94_R1.8661.00
82_W164_E1.8541.00
352_R382_T1.8511.00
46_Q85_D1.8431.00
246_M283_V1.8351.00
271_L279_R1.8321.00
225_S228_W1.8281.00
237_S242_Y1.8131.00
86_D131_P1.8011.00
192_D196_T1.7931.00
445_P465_L1.7821.00
260_G402_M1.7781.00
227_G285_M1.7511.00
403_F434_V1.7461.00
387_T431_E1.7381.00
69_G74_Y1.7361.00
253_H267_S1.7271.00
180_D228_W1.6911.00
372_N375_D1.6651.00
230_R280_E1.6451.00
81_V87_V1.6421.00
90_I125_D1.6401.00
98_N121_S1.6321.00
401_V466_V1.6111.00
254_V279_R1.6001.00
158_A187_Q1.6001.00
388_V448_F1.5841.00
223_E318_T1.5481.00
293_I315_L1.5391.00
257_G279_R1.5351.00
398_I436_F1.5351.00
230_R255_I1.5291.00
52_V99_V1.5221.00
278_R422_D1.5201.00
184_V233_L1.5201.00
336_L339_R1.5031.00
246_M293_I1.4951.00
383_W437_G1.4881.00
52_V70_I1.4851.00
52_V91_Y1.4781.00
447_Y461_I1.4751.00
221_Y316_V1.4721.00
139_L259_Q1.4651.00
404_Q420_W1.4641.00
290_E316_V1.4471.00
377_T465_L1.4461.00
78_T183_P1.4361.00
81_V132_I1.4321.00
386_W434_V1.4231.00
54_R96_T1.4221.00
160_M183_P1.4211.00
408_V430_V1.4101.00
233_L271_L1.4071.00
288_G291_V1.3991.00
61_P191_L1.3951.00
271_L281_I1.3801.00
274_A425_W1.3701.00
456_A461_I1.3681.00
83_K166_E1.3591.00
354_R357_S1.3481.00
243_Q270_Q1.3471.00
405_I424_V1.3451.00
88_K127_A1.3391.00
352_R356_I1.3301.00
333_T336_L1.3291.00
243_Q272_S1.3261.00
393_P425_W1.3211.00
58_S62_G1.3211.00
143_A152_Q1.3101.00
451_Q455_M1.2971.00
450_S455_M1.2891.00
440_S443_H1.2881.00
385_R433_L1.2651.00
329_L333_T1.2641.00
353_S387_T1.2601.00
364_I396_F1.2571.00
82_W166_E1.2541.00
70_I141_Y1.2491.00
217_V220_P1.2451.00
445_P463_Q1.2341.00
254_V268_V1.2321.00
395_A452_T1.2321.00
398_I448_F1.2291.00
164_E181_D1.2271.00
58_S61_P1.2221.00
246_M252_L1.2201.00
182_F231_L1.2121.00
400_G446_F1.2101.00
186_I244_L1.2001.00
67_V189_K1.1961.00
347_A350_P1.1951.00
453_L456_A1.1911.00
107_Q440_S1.1901.00
291_V295_C1.1901.00
53_Q69_G1.1861.00
81_V161_W1.1821.00
87_V161_W1.1771.00
138_T232_R1.1771.00
70_I101_M1.1671.00
350_P353_S1.1651.00
407_N431_E1.1601.00
225_S318_T1.1571.00
99_V152_Q1.1521.00
351_I360_D1.1521.00
252_L283_V1.1461.00
57_W69_G1.1371.00
314_I317_S1.1371.00
182_F222_V1.1371.00
378_A384_E1.1361.00
144_N450_S1.1351.00
82_W169_K1.1331.00
81_V163_V1.1301.00
337_P340_L1.1271.00
406_R435_Y1.1261.00
224_V229_V1.1251.00
153_V453_L1.1231.00
80_R181_D1.1221.00
285_M317_S1.1131.00
154_Y238_N1.1121.00
173_I178_G1.1001.00
350_P354_R1.0951.00
70_I157_L1.0941.00
77_P141_Y1.0911.00
48_L81_V1.0891.00
244_L293_I1.0841.00
68_W155_N1.0841.00
313_S317_S1.0821.00
356_I364_I1.0771.00
449_N455_M1.0731.00
68_W157_L1.0701.00
50_M79_I1.0681.00
187_Q213_L1.0681.00
186_I242_Y1.0671.00
367_Q370_D1.0611.00
77_P159_G1.0601.00
221_Y318_T1.0491.00
333_T339_R1.0471.00
158_A236_A1.0321.00
212_L311_P1.0321.00
58_S64_R1.0271.00
211_T218_Q1.0261.00
232_R280_E1.0251.00
45_G88_K1.0181.00
82_W85_D1.0161.00
244_L271_L1.0161.00
396_F448_F1.0151.00
187_Q236_A1.0151.00
448_F462_G1.0141.00
78_T141_Y1.0111.00
394_Q450_S1.0111.00
238_N454_E1.0101.00
394_Q397_H1.0091.00
384_E436_F1.0051.00
334_D338_M1.0051.00
91_Y101_M1.0031.00
403_F424_V1.0001.00
214_V313_S0.9991.00
312_S317_S0.9981.00
91_Y99_V0.9961.00
117_A126_W0.9961.00
241_R274_A0.9941.00
100_S116_P0.9921.00
212_L242_Y0.9911.00
255_I282_L0.9891.00
394_Q451_Q0.9861.00
231_L283_V0.9841.00
120_M126_W0.9751.00
201_E205_G0.9721.00
355_D387_T0.9701.00
250_R291_V0.9671.00
329_L332_V0.9661.00
224_V315_L0.9641.00
229_V285_M0.9581.00
350_P356_I0.9571.00
333_T337_P0.9571.00
250_R317_S0.9531.00
396_F460_S0.9491.00
138_T234_L0.9491.00
144_N451_Q0.9491.00
138_T160_M0.9471.00
348_G351_I0.9461.00
181_D232_R0.9451.00
378_A438_Q0.9351.00
45_G86_D0.9341.00
257_G421_K0.9331.00
228_W282_L0.9311.00
185_I234_L0.9281.00
83_K135_N0.9221.00
330_P333_T0.9211.00
76_G216_G0.9160.99
233_L273_L0.9120.99
193_N196_T0.9040.99
332_V335_S0.9020.99
359_G363_G0.9020.99
394_Q455_M0.9020.99
314_I319_L0.9020.99
144_N449_N0.9000.99
264_A417_D0.8970.99
180_D229_V0.8960.99
102_T144_N0.8960.99
381_G438_Q0.8950.99
132_I161_W0.8860.99
103_V130_L0.8830.99
297_E300_S0.8820.99
426_V432_L0.8820.99
398_I434_V0.8820.99
224_V283_V0.8770.99
68_W96_T0.8770.99
245_Q270_Q0.8750.99
83_K136_A0.8730.99
333_T338_M0.8730.99
343_T346_M0.8730.99
336_L340_L0.8720.99
104_A144_N0.8710.99
341_L345_I0.8700.99
153_V158_A0.8670.99
259_Q402_M0.8660.99
142_H451_Q0.8640.99
313_S319_L0.8640.99
364_I369_W0.8630.99
342_P345_I0.8620.99
138_T181_D0.8620.99
353_S385_R0.8600.99
245_Q296_G0.8550.99
142_H450_S0.8510.99
439_P443_H0.8490.99
402_M420_W0.8400.99
74_Y158_A0.8390.99
351_I358_L0.8380.99
190_R197_P0.8380.99
76_G141_Y0.8370.99
342_P346_M0.8360.99
330_P334_D0.8350.99
104_A450_S0.8330.99
104_A451_Q0.8320.99
71_N75_L0.8310.99
249_G287_N0.8290.99
107_Q439_P0.8270.99
447_Y456_A0.8260.99
394_Q399_E0.8220.99
89_L103_V0.8210.99
379_Q384_E0.8180.99
352_R355_D0.8180.99
181_D230_R0.8130.99
97_E152_Q0.8110.99
116_P145_T0.8110.99
68_W95_L0.8100.99
352_R358_L0.8090.99
363_G368_L0.8090.99
91_Y103_V0.8040.99
312_S315_L0.8040.99
398_I403_F0.7980.99
331_L336_L0.7980.99
398_I401_V0.7970.99
254_V271_L0.7960.99
390_A428_G0.7960.99
94_R123_N0.7930.99
106_L163_V0.7920.99
256_S261_F0.7900.98
365_N368_L0.7880.98
370_D373_R0.7870.98
343_T347_A0.7860.98
374_I378_A0.7830.98
351_I354_R0.7820.98
155_N194_F0.7810.98
310_E313_S0.7790.98
328_L338_M0.7770.98
165_D168_S0.7760.98
389_R431_E0.7750.98
102_T113_M0.7740.98
245_Q294_T0.7670.98
178_G181_D0.7670.98
103_V161_W0.7670.98
347_A351_I0.7660.98
354_R360_D0.7650.98
78_T162_L0.7570.98
309_F312_S0.7570.98
48_L87_V0.7560.98
405_I432_L0.7540.98
107_Q402_M0.7520.98
191_L211_T0.7520.98
79_I161_W0.7520.98
226_R286_S0.7480.98
329_L337_P0.7480.98
345_I349_S0.7460.98
363_G367_Q0.7460.98
107_Q135_N0.7450.98
104_A455_M0.7440.98
106_L161_W0.7410.98
247_N292_S0.7400.98
251_P286_S0.7400.98
386_W464_L0.7390.98
136_A261_F0.7390.98
331_L334_D0.7370.98
173_I261_F0.7370.98
69_G72_G0.7370.98
72_G75_L0.7370.98
254_V266_V0.7360.98
52_V101_M0.7360.98
257_G277_E0.7360.98
380_Q443_H0.7360.98
183_P234_L0.7350.98
353_S359_G0.7320.98
350_P385_R0.7310.97
246_M250_R0.7290.97
102_T399_E0.7290.97
257_G262_L0.7290.97
245_Q269_K0.7280.97
144_N455_M0.7260.97
351_I355_D0.7230.97
241_R272_S0.7210.97
409_N430_V0.7190.97
142_H394_Q0.7180.97
109_P112_L0.7180.97
70_I76_G0.7180.97
448_F464_L0.7180.97
290_E295_C0.7170.97
191_L210_D0.7170.97
286_S291_V0.7160.97
394_Q449_N0.7150.97
202_P205_G0.7120.97
334_D339_R0.7110.97
158_A185_I0.7100.97
104_A142_H0.7090.97
344_E347_A0.7090.97
117_A120_M0.7080.97
165_D261_F0.7080.97
106_L130_L0.7020.97
288_G319_L0.7020.97
320_V323_L0.7010.97
180_D225_S0.7000.97
355_D389_R0.6990.97
140_W144_N0.6980.97
190_R210_D0.6970.97
342_P347_A0.6960.97
47_P129_V0.6940.97
201_E204_S0.6940.97
186_I233_L0.6910.96
381_G437_G0.6910.96
225_S229_V0.6880.96
330_P337_P0.6880.96
91_Y128_P0.6860.96
250_R286_S0.6850.96
224_V317_S0.6840.96
102_T394_Q0.6830.96
95_L122_P0.6830.96
348_G354_R0.6830.96
404_Q435_Y0.6820.96
144_N394_Q0.6810.96
200_N203_G0.6790.96
335_S338_M0.6780.96
104_A394_Q0.6770.96
319_L322_T0.6760.96
364_I370_D0.6760.96
322_T326_T0.6740.96
328_L339_R0.6710.96
364_I368_L0.6700.96
365_N376_V0.6680.96
100_S117_A0.6670.96
349_S352_R0.6670.96
58_S63_T0.6660.96
335_S339_R0.6650.96
52_V157_L0.6650.96
376_V462_G0.6640.96
288_G293_I0.6630.96
83_K133_R0.6620.96
393_P427_D0.6620.96
87_V130_L0.6610.95
283_V315_L0.6590.95
223_E320_V0.6570.95
325_P329_L0.6560.95
81_V89_L0.6560.95
413_P416_E0.6550.95
112_L115_G0.6540.95
144_N399_E0.6540.95
292_S314_I0.6530.95
94_R125_D0.6520.95
362_P368_L0.6510.95
63_T191_L0.6500.95
45_G48_L0.6500.95
132_I135_N0.6490.95
316_V320_V0.6480.95
257_G419_G0.6480.95
343_T348_G0.6460.95
180_D227_G0.6460.95
262_L266_V0.6460.95
274_A277_E0.6450.95
401_V436_F0.6440.95
159_G216_G0.6440.95
332_V340_L0.6430.95
233_L293_I0.6430.95
104_A399_E0.6430.95
350_P360_D0.6400.95
288_G295_C0.6390.95
357_S391_D0.6350.94
206_G209_G0.6340.94
330_P335_S0.6340.94
329_L336_L0.6330.94
182_F229_V0.6310.94
364_I367_Q0.6310.94
356_I360_D0.6300.94
78_T164_E0.6290.94
283_V293_I0.6270.94
332_V337_P0.6270.94
331_L335_S0.6230.94
399_E449_N0.6210.94
311_P315_L0.6210.94
315_L319_L0.6200.94
103_V400_G0.6200.94
406_R433_L0.6180.94
347_A354_R0.6170.94
118_R121_S0.6170.94
311_P314_I0.6160.93
334_D340_L0.6160.93
81_V106_L0.6150.93
212_L297_E0.6150.93
169_K174_P0.6130.93
253_H284_D0.6100.93
212_L295_C0.6090.93
55_A67_V0.6070.93
151_Q155_N0.6060.93
365_N370_D0.6030.93
436_F440_S0.6000.93
409_N431_E0.5980.92
312_S316_V0.5950.92
397_H450_S0.5940.92
78_T161_W0.5940.92
174_P178_G0.5910.92
316_V321_L0.5900.92
186_I295_C0.5900.92
138_T256_S0.5900.92
247_N250_R0.5900.92
252_L268_V0.5900.92
447_Y453_L0.5890.92
332_V338_M0.5870.92
346_M355_D0.5870.92
42_S45_G0.5860.92
104_A449_N0.5860.92
323_L327_G0.5860.92
262_L419_G0.5840.92
102_T105_G0.5820.91
383_W435_Y0.5810.91
408_V432_L0.5810.91
373_R377_T0.5800.91
332_V336_L0.5800.91
113_M144_N0.5790.91
447_Y463_Q0.5780.91
334_D337_P0.5770.91
333_T340_L0.5760.91
102_T449_N0.5750.91
96_T122_P0.5750.91
375_D378_A0.5740.91
348_G352_R0.5740.91
243_Q296_G0.5730.91
289_D320_V0.5730.91
119_M145_T0.5720.91
99_V143_A0.5710.91
136_A163_V0.5700.91
322_T325_P0.5700.91
291_V317_S0.5700.91
407_N432_L0.5690.90
440_S444_F0.5680.90
399_E450_S0.5670.90
71_N77_P0.5670.90
184_V293_I0.5670.90
100_S145_T0.5660.90
181_D280_E0.5620.90
186_I273_L0.5610.90
135_N402_M0.5610.90
223_E226_R0.5600.90
200_N204_S0.5590.90
330_P336_L0.5590.90
354_R376_V0.5580.90
330_P338_M0.5580.90
106_L139_L0.5560.89
374_I377_T0.5560.89
328_L335_S0.5560.89
212_L218_Q0.5540.89
254_V262_L0.5540.89
70_I73_R0.5530.89
44_R85_D0.5520.89
362_P366_G0.5520.89
397_H451_Q0.5510.89
375_D463_Q0.5500.89
54_R68_W0.5500.89
399_E451_Q0.5490.89
102_T451_Q0.5480.89
91_Y161_W0.5470.89
43_R46_Q0.5470.89
328_L334_D0.5460.89
48_L89_L0.5450.89
314_I321_L0.5450.89
66_S196_T0.5440.88
78_T81_V0.5440.88
315_L324_R0.5410.88
330_P340_L0.5410.88
237_S275_P0.5400.88
253_H265_P0.5380.88
351_I357_S0.5380.88
70_I99_V0.5380.88
348_G353_S0.5370.88
63_T66_S0.5370.88
349_S355_D0.5370.88
272_S427_D0.5370.88
350_P358_L0.5350.88
194_F197_P0.5340.88
133_R440_S0.5340.88
316_V319_L0.5320.87
76_G157_L0.5310.87
250_R285_M0.5310.87
89_L101_M0.5300.87
80_R162_L0.5300.87
73_R76_G0.5290.87
231_L285_M0.5290.87
318_T321_L0.5280.87
341_L347_A0.5270.87
382_T438_Q0.5260.87
75_L141_Y0.5260.87
249_G286_S0.5240.87
330_P339_R0.5240.87
219_S314_I0.5230.86
357_S389_R0.5230.86
95_L99_V0.5220.86
130_L161_W0.5220.86
70_I91_Y0.5210.86
223_E316_V0.5210.86
346_M350_P0.5190.86
398_I464_L0.5190.86
50_M141_Y0.5180.86
151_Q454_E0.5180.86
315_L321_L0.5170.86
311_P317_S0.5170.86
366_G370_D0.5160.86
52_V120_M0.5160.86
204_S207_F0.5150.86
376_V464_L0.5150.86
85_D132_I0.5150.86
162_L234_L0.5140.85
290_E318_T0.5140.85
328_L331_L0.5140.85
103_V106_L0.5130.85
366_G369_W0.5130.85
357_S360_D0.5120.85
99_V157_L0.5120.85
350_P357_S0.5100.85
260_G277_E0.5100.85
142_H449_N0.5090.85
345_I348_G0.5080.85
329_L334_D0.5080.85
209_G240_R0.5080.85
349_S354_R0.5080.85
293_I298_A0.5070.85
138_T280_E0.5060.85
399_E455_M0.5060.85
206_G239_S0.5060.85
325_P334_D0.5040.84
353_S357_S0.5040.84
239_S452_T0.5040.84
209_G212_L0.5020.84
361_D368_L0.5000.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2uxtA 1 0.8915 100 0.191 Contact Map
3zx1A 1 0.9213 100 0.203 Contact Map
4e9sA 1 0.917 100 0.211 Contact Map
2xu9A 1 0.8894 100 0.212 Contact Map
3abgA 1 0.9404 100 0.219 Contact Map
1zpuA 3 0.8766 100 0.239 Contact Map
3sqrA 1 0.8957 100 0.24 Contact Map
2wsdA 1 0.9213 100 0.24 Contact Map
3gyrA 4 0.9468 100 0.24 Contact Map
1aozA 3 0.8723 100 0.242 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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