GREMLIN Database
MAO1 - NAD-dependent malic enzyme
UniProt: P26616 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10948
Length: 565 (537)
Sequences: 1486 (838)
Seq/√Len: 36.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
398_E402_R8.6351.00
202_Q206_N6.0311.00
221_D225_E4.2631.00
136_D236_Q4.0911.00
64_Y99_M4.0451.00
485_E533_Q4.0411.00
312_E355_L4.0281.00
92_V103_I4.0161.00
148_K189_Y3.9611.00
405_H434_T3.8001.00
483_T535_V3.6621.00
152_V230_F3.6611.00
224_Y255_P3.5851.00
401_I433_W3.3361.00
428_Q432_A3.2501.00
299_V377_V3.2311.00
373_S376_D3.1881.00
90_R94_N3.1611.00
343_D358_K3.0611.00
133_H229_E3.0311.00
110_A114_R2.9541.00
405_H437_N2.9031.00
261_R484_D2.9011.00
200_N219_T2.8791.00
435_E452_K2.8641.00
195_L227_V2.8561.00
375_L399_E2.7581.00
228_D263_E2.7281.00
202_Q216_P2.7181.00
379_R403_E2.7101.00
60_A91_L2.6521.00
402_R435_E2.5981.00
245_F266_S2.5941.00
425_A430_I2.5851.00
231_I264_I2.5651.00
403_E407_H2.5021.00
324_S327_A2.4361.00
67_F72_D2.3991.00
524_F548_I2.3991.00
520_R549_D2.3791.00
28_K36_E2.3781.00
474_V482_I2.3751.00
483_T533_Q2.3401.00
529_M533_Q2.3330.99
403_E406_K2.3310.99
500_L504_G2.2890.99
230_F234_V2.2290.99
375_L400_I2.2060.99
529_M532_Q2.1820.99
140_Q237_R2.1710.99
275_A313_M2.1630.99
65_Q98_E2.1320.99
337_R352_Q2.1120.99
301_L395_L2.0800.99
431_I451_W2.0730.99
404_M413_V2.0620.99
38_R43_L2.0160.99
70_E73_K2.0100.98
95_H98_E1.9940.98
323_L331_K1.9660.98
85_E123_R1.9620.98
252_N255_P1.9280.98
292_Q295_E1.9110.98
409_P437_N1.9050.98
469_G473_G1.9040.98
61_W95_H1.8990.98
69_T72_D1.8830.98
228_D259_R1.8830.98
466_I470_I1.8760.98
401_I413_V1.8740.98
52_T55_E1.8550.97
426_T429_D1.8540.97
486_M530_A1.8490.97
53_I90_R1.8470.97
127_I135_M1.8370.97
129_Y218_I1.8130.97
439_L508_V1.8110.97
310_I389_V1.7910.97
282_L314_I1.7860.97
546_Q550_D1.7740.97
282_L385_I1.7650.96
130_Q213_W1.7530.96
105_T444_S1.7420.96
228_D232_Q1.7340.96
348_L356_V1.7310.96
378_V400_I1.7280.96
301_L392_Q1.6970.96
545_Q549_D1.6950.96
240_D478_G1.6720.95
57_A90_R1.6690.95
265_C474_V1.6530.95
205_L216_P1.6260.94
325_E329_R1.6250.94
450_V455_I1.6190.94
327_A331_K1.6100.94
231_I243_L1.5990.94
150_I234_V1.5880.94
375_L379_R1.5770.93
540_S543_A1.5770.93
296_K384_D1.5770.93
294_S321_E1.5750.93
514_D517_K1.5670.93
224_Y252_N1.5660.93
201_N204_L1.5580.93
382_K407_H1.5570.93
299_V381_V1.5510.93
135_M226_F1.5500.93
299_V335_V1.5490.93
157_R161_L1.5450.93
320_R492_E1.5430.93
398_E433_W1.5390.93
281_T509_L1.5310.92
156_E252_N1.5260.92
61_W65_Q1.5250.92
156_E200_N1.5210.92
57_A94_N1.5120.92
129_Y226_F1.5070.92
152_V234_V1.5050.92
315_I329_R1.4980.92
97_D513_K1.4970.91
543_A546_Q1.4930.91
231_I245_F1.4930.91
528_K532_Q1.4840.91
117_E207_D1.4640.91
193_V230_F1.4460.90
227_V256_L1.4450.90
243_L264_I1.4420.90
483_T529_M1.4420.90
524_F545_Q1.4360.90
401_I434_T1.4340.90
51_E59_R1.4320.90
156_E249_A1.4230.89
450_V453_D1.4100.89
483_T486_M1.4020.89
520_R545_Q1.4020.89
129_Y213_W1.3980.88
64_Y102_V1.3980.88
43_L131_N1.3930.88
476_A527_G1.3840.88
53_I86_T1.3780.88
215_N218_I1.3690.87
473_G477_S1.3680.87
332_V357_Q1.3670.87
338_F352_Q1.3660.87
398_E435_E1.3640.87
61_W99_M1.3610.87
413_V430_I1.3580.87
427_P440_V1.3570.87
473_G479_A1.3530.87
379_R399_E1.3390.86
461_C509_L1.3350.86
451_W456_Y1.3330.86
431_I458_I1.3320.86
473_G530_A1.3310.86
130_Q215_N1.3260.86
298_I318_T1.3250.86
30_S211_M1.3240.85
149_V471_G1.3180.85
391_G395_L1.3100.85
285_A412_I1.3070.85
193_V226_F1.3000.84
528_K541_A1.2950.84
169_M194_V1.2780.83
61_W98_E1.2760.83
300_F311_A1.2740.83
473_G526_V1.2700.83
477_S527_G1.2560.82
132_R222_E1.2560.82
341_L352_Q1.2460.82
357_Q381_V1.2450.82
529_M535_V1.2430.82
375_L403_E1.2420.82
282_L298_I1.2390.81
429_D432_A1.2360.81
425_A440_V1.2350.81
105_T109_G1.2320.81
435_E451_W1.2290.81
479_A486_M1.2240.81
318_T323_L1.2140.80
112_C161_L1.2140.80
242_L482_I1.2120.80
61_W91_L1.2070.80
221_D224_Y1.1970.79
153_T194_V1.1940.79
84_N557_Y1.1930.79
124_G169_M1.1910.79
235_K264_I1.1880.79
337_R341_L1.1800.78
402_R437_N1.1790.78
277_V494_L1.1750.78
401_I430_I1.1720.78
78_R88_F1.1710.78
20_L40_F1.1670.77
431_I456_Y1.1610.77
109_G467_F1.1430.76
132_R229_E1.1370.75
297_K384_D1.1370.75
60_A76_Y1.1350.75
35_E39_N1.1320.75
521_A545_Q1.1270.75
281_T414_M1.1250.75
17_G20_L1.1250.75
80_I108_V1.1220.74
394_G429_D1.1180.74
195_L226_F1.1160.74
110_A113_E1.1120.74
112_C158_I1.1070.73
382_K406_K1.1070.73
333_F381_V1.1010.73
81_Q123_R1.0980.73
330_Q358_K1.0980.73
335_V374_L1.0940.73
297_K381_V1.0870.72
93_N516_Q1.0860.72
185_I472_L1.0830.72
136_D237_R1.0790.71
219_T252_N1.0690.71
136_D229_E1.0660.71
254_M352_Q1.0630.70
277_V522_I1.0610.70
132_R225_E1.0600.70
105_T467_F1.0590.70
71_I118_I1.0520.70
135_M139_L1.0470.69
496_Q525_A1.0460.69
115_F173_I1.0440.69
448_P457_P1.0440.69
318_T331_K1.0440.69
431_I436_G1.0420.69
185_I475_I1.0350.68
335_V377_V1.0340.68
400_I403_E1.0320.68
312_E354_K1.0310.68
49_V214_R1.0310.68
344_K359_R1.0280.68
374_L386_L1.0260.68
341_L356_V1.0190.67
235_K243_L1.0110.66
82_D121_R1.0100.66
539_T542_E1.0090.66
489_S525_A1.0060.66
112_C157_R1.0060.66
233_A237_R1.0040.66
425_A442_T1.0040.66
520_R552_F1.0020.66
499_P503_N1.0020.66
228_D260_Y1.0010.66
319_Q325_E1.0010.66
376_D379_R1.0010.66
234_V241_V1.0000.66
112_C170_G0.9950.65
262_N481_R0.9900.65
327_A330_Q0.9890.65
161_L164_Q0.9890.65
182_C389_V0.9870.65
127_I139_L0.9850.64
81_Q85_E0.9800.64
27_N32_F0.9770.64
20_L42_L0.9710.63
520_R524_F0.9710.63
315_I319_Q0.9650.63
15_Y20_L0.9650.63
232_Q263_E0.9630.63
249_A305_S0.9600.62
376_D380_N0.9590.62
49_V55_E0.9580.62
155_G194_V0.9570.62
91_L99_M0.9530.62
250_Q305_S0.9500.62
28_K558_R0.9430.61
68_K72_D0.9380.61
494_L522_I0.9360.60
183_G249_A0.9350.60
399_E403_E0.9350.60
54_E452_K0.9320.60
108_V174_G0.9230.59
46_L50_V0.9210.59
65_Q95_H0.9210.59
129_Y135_M0.9210.59
318_T322_G0.9190.59
281_T459_A0.9190.59
343_D356_V0.9190.59
478_G538_K0.9150.59
200_N216_P0.9100.58
105_T277_V0.9090.58
174_G181_A0.9090.58
308_C334_M0.9080.58
288_A410_R0.9070.58
343_D359_R0.9060.58
78_R81_Q0.9060.58
146_N189_Y0.9060.58
31_A557_Y0.9050.58
512_L522_I0.9040.58
470_I487_L0.9020.57
79_N83_T0.9010.57
478_G537_V0.9000.57
75_I120_R0.8970.57
326_E330_Q0.8950.57
205_L214_R0.8940.57
493_T521_A0.8910.57
516_Q552_F0.8900.56
110_A421_S0.8890.56
434_T518_V0.8880.56
149_V179_Y0.8860.56
82_D123_R0.8830.56
278_T341_L0.8810.56
105_T446_F0.8800.56
398_E434_T0.8780.55
442_T458_I0.8780.55
295_E327_A0.8770.55
156_E219_T0.8770.55
402_R434_T0.8720.55
466_I494_L0.8690.55
332_V377_V0.8690.55
430_I440_V0.8650.54
476_A547_A0.8640.54
345_M352_Q0.8630.54
501_V504_G0.8610.54
151_V244_Q0.8590.54
67_F75_I0.8590.54
202_Q205_L0.8570.54
157_R170_G0.8500.53
200_N203_Q0.8490.53
372_L377_V0.8480.53
293_L318_T0.8480.53
108_V169_M0.8470.53
127_I138_I0.8470.53
136_D140_Q0.8460.53
186_S189_Y0.8460.53
481_R535_V0.8440.52
15_Y23_F0.8430.52
333_F357_Q0.8430.52
80_I83_T0.8420.52
425_A553_W0.8410.52
338_F341_L0.8400.52
135_M229_E0.8390.52
131_N134_N0.8350.52
112_C465_F0.8340.52
427_P442_T0.8340.52
117_E209_L0.8300.51
29_G121_R0.8300.51
383_P404_M0.8270.51
291_G296_K0.8260.51
116_S205_L0.8220.51
377_V381_V0.8190.50
540_S544_L0.8180.50
174_G179_Y0.8170.50
531_Q541_A0.8160.50
294_S323_L0.8140.50
405_H408_C0.8120.50
157_R465_F0.8110.50
420_T445_P0.8110.50
75_I118_I0.8050.49
227_V266_S0.8030.49
193_V234_V0.8030.49
69_T110_A0.8020.49
316_S325_E0.8000.49
51_E83_T0.7980.48
139_L237_R0.7980.48
299_V400_I0.7890.48
166_I227_V0.7870.48
317_Q321_E0.7850.47
113_E421_S0.7830.47
288_A439_L0.7820.47
254_M355_L0.7810.47
301_L374_L0.7800.47
497_Y521_A0.7780.47
398_E432_A0.7770.47
485_E529_M0.7750.46
416_L446_F0.7710.46
59_R441_A0.7700.46
249_A252_N0.7690.46
546_Q549_D0.7680.46
245_F264_I0.7680.46
225_E399_E0.7670.46
62_I65_Q0.7660.46
398_E401_I0.7650.46
393_T397_T0.7650.46
297_K383_P0.7650.46
415_P433_W0.7650.46
122_S414_M0.7650.46
156_E389_V0.7630.45
174_G460_Q0.7630.45
32_F36_E0.7610.45
75_I522_I0.7600.45
173_I319_Q0.7570.45
423_V446_F0.7560.45
254_M351_F0.7560.45
337_R391_G0.7550.45
112_C275_A0.7530.45
157_R172_P0.7520.44
412_I441_A0.7490.44
476_A551_N0.7470.44
194_V341_L0.7460.44
544_L548_I0.7460.44
74_H313_M0.7460.44
287_R496_Q0.7450.44
300_F387_I0.7450.44
51_E76_Y0.7450.44
250_Q352_Q0.7440.44
136_D233_A0.7440.44
527_G531_Q0.7440.44
30_S555_A0.7410.44
371_V377_V0.7390.43
166_I211_M0.7370.43
161_L170_G0.7350.43
199_T205_L0.7350.43
254_M271_I0.7290.43
499_P502_L0.7290.43
282_L414_M0.7280.42
383_P407_H0.7270.42
42_L46_L0.7260.42
298_I314_I0.7260.42
73_K98_E0.7250.42
430_I442_T0.7250.42
420_T448_P0.7240.42
43_L134_N0.7240.42
397_T400_I0.7220.42
319_Q546_Q0.7200.42
390_S395_L0.7200.42
530_A535_V0.7200.42
108_V161_L0.7190.42
239_P555_A0.7170.41
319_Q323_L0.7170.41
515_I522_I0.7170.41
307_G508_V0.7170.41
299_V357_Q0.7160.41
389_V465_F0.7140.41
321_E492_E0.7120.41
129_Y132_R0.7120.41
265_C275_A0.7110.41
286_S291_G0.7110.41
62_I117_E0.7100.41
497_Y514_D0.7050.40
342_T359_R0.7050.40
156_E223_Y0.7050.40
97_D511_E0.7040.40
33_S36_E0.7040.40
218_I226_F0.7030.40
316_S319_Q0.7020.40
242_L265_C0.7010.40
493_T497_Y0.7010.40
67_F76_Y0.7010.40
57_A91_L0.6990.40
45_L141_N0.6980.40
278_T461_C0.6970.40
479_A482_I0.6960.40
85_E275_A0.6950.40
182_C512_L0.6950.40
178_L244_Q0.6940.40
479_A526_V0.6940.40
31_A52_T0.6930.39
176_L459_A0.6920.39
161_L465_F0.6920.39
111_A124_G0.6920.39
480_S537_V0.6910.39
267_F445_P0.6900.39
112_C172_P0.6890.39
531_Q536_A0.6870.39
245_F465_F0.6850.39
223_Y249_A0.6840.39
518_V522_I0.6840.39
459_A498_S0.6830.39
16_A41_N0.6830.39
513_K532_Q0.6820.39
28_K32_F0.6810.38
472_L552_F0.6790.38
156_E464_A0.6790.38
50_V438_A0.6780.38
492_E496_Q0.6770.38
67_F464_A0.6760.38
350_P353_T0.6760.38
244_Q461_C0.6760.38
73_K102_V0.6750.38
121_R410_R0.6750.38
338_F345_M0.6750.38
30_S51_E0.6750.38
149_V242_L0.6740.38
74_H275_A0.6730.38
515_I519_S0.6720.38
169_M172_P0.6710.38
324_S330_Q0.6710.38
116_S167_G0.6690.37
307_G389_V0.6680.37
337_R345_M0.6650.37
402_R433_W0.6640.37
448_P455_I0.6640.37
220_D252_N0.6630.37
205_L448_P0.6630.37
337_R392_Q0.6630.37
88_F92_V0.6620.37
16_A20_L0.6610.37
301_L335_V0.6610.37
391_G422_R0.6600.37
405_H435_E0.6590.37
90_R556_E0.6570.37
201_N206_N0.6560.36
502_L514_D0.6540.36
464_A548_I0.6530.36
161_L389_V0.6530.36
193_V227_V0.6530.36
352_Q509_L0.6530.36
178_L266_S0.6520.36
446_F467_F0.6500.36
56_Q87_L0.6500.36
459_A509_L0.6490.36
112_C389_V0.6490.36
245_F256_L0.6480.36
254_M305_S0.6480.36
99_M102_V0.6480.36
330_Q378_V0.6450.36
111_A441_A0.6450.36
426_T440_V0.6450.36
282_L286_S0.6450.36
36_E56_Q0.6450.36
267_F444_S0.6440.35
375_L378_V0.6440.35
315_I356_V0.6430.35
547_A551_N0.6420.35
177_S522_I0.6410.35
86_T307_G0.6410.35
465_F522_I0.6410.35
303_A334_M0.6400.35
407_H434_T0.6400.35
222_E330_Q0.6390.35
197_V223_Y0.6380.35
252_N464_A0.6380.35
332_V384_D0.6360.35
393_T429_D0.6350.35
54_E94_N0.6340.35
76_Y119_Y0.6340.35
171_I418_N0.6340.35
205_L215_N0.6320.35
123_R265_C0.6320.35
440_V449_V0.6310.34
105_T391_G0.6310.34
434_T438_A0.6290.34
112_C155_G0.6270.34
182_C310_I0.6260.34
520_R548_I0.6260.34
516_Q554_Q0.6250.34
225_E229_E0.6240.34
108_V244_Q0.6240.34
330_Q432_A0.6240.34
236_Q402_R0.6240.34
382_K430_I0.6230.34
306_A418_N0.6230.34
56_Q84_N0.6230.34
275_A389_V0.6220.34
114_R117_E0.6220.34
281_T288_A0.6220.34
483_T530_A0.6220.34
85_E120_R0.6210.34
479_A535_V0.6210.34
224_Y227_V0.6200.34
222_E225_E0.6200.34
157_R178_L0.6200.34
71_I75_I0.6190.34
528_K531_Q0.6190.34
181_A461_C0.6180.33
170_G466_I0.6180.33
286_S292_Q0.6170.33
425_A429_D0.6170.33
112_C164_Q0.6160.33
250_Q349_L0.6150.33
316_S329_R0.6150.33
278_T416_L0.6130.33
112_C244_Q0.6120.33
53_I57_A0.6120.33
147_I237_R0.6100.33
430_I553_W0.6100.33
135_M371_V0.6090.33
448_P481_R0.6090.33
224_Y228_D0.6090.33
105_T421_S0.6080.33
493_T522_I0.6070.33
105_T271_I0.6070.33
125_V142_V0.6050.32
128_S226_F0.6040.32
114_R263_E0.6040.32
129_Y548_I0.6040.32
313_M487_L0.6040.32
373_S400_I0.6030.32
384_D408_C0.6030.32
17_G73_K0.6010.32
157_R389_V0.6000.32
423_V426_T0.6000.32
30_S80_I0.5990.32
398_E429_D0.5980.32
203_Q378_V0.5970.32
190_T244_Q0.5970.32
403_E408_C0.5970.32
137_D454_K0.5970.32
149_V178_L0.5970.32
23_F26_L0.5960.32
245_F375_L0.5950.32
70_E110_A0.5950.32
67_F79_N0.5950.32
112_C149_V0.5950.32
149_V161_L0.5930.32
298_I385_I0.5930.32
391_G416_L0.5930.32
220_D223_Y0.5930.32
152_V201_N0.5910.31
386_L469_G0.5900.31
34_M38_R0.5900.31
373_S377_V0.5900.31
166_I487_L0.5890.31
89_Y413_V0.5890.31
115_F177_S0.5880.31
21_L46_L0.5880.31
249_A464_A0.5880.31
156_E310_I0.5860.31
397_T429_D0.5850.31
161_L172_P0.5850.31
178_L245_F0.5840.31
140_Q214_R0.5840.31
115_F310_I0.5840.31
310_I464_A0.5840.31
31_A56_Q0.5840.31
156_E509_L0.5830.31
125_V133_H0.5830.31
245_F303_A0.5820.31
465_F512_L0.5810.31
19_V23_F0.5810.31
301_L391_G0.5800.31
242_L470_I0.5800.31
24_P27_N0.5790.30
142_V553_W0.5780.30
244_Q465_F0.5780.30
245_F300_F0.5770.30
405_H409_P0.5760.30
89_Y221_D0.5750.30
50_V69_T0.5750.30
126_F148_K0.5750.30
469_G530_A0.5750.30
172_P194_V0.5750.30
454_K505_E0.5750.30
109_G153_T0.5740.30
241_V256_L0.5740.30
350_P390_S0.5730.30
382_K480_S0.5730.30
244_Q267_F0.5720.30
128_S131_N0.5710.30
219_T222_E0.5710.30
115_F279_V0.5710.30
152_V195_L0.5710.30
158_I171_I0.5710.30
59_R209_L0.5690.30
279_V317_Q0.5680.30
524_F528_K0.5680.30
88_F483_T0.5680.30
132_R233_A0.5670.30
418_N445_P0.5660.30
415_P522_I0.5660.30
254_M312_E0.5660.30
427_P446_F0.5650.29
403_E439_L0.5650.29
157_R250_Q0.5650.29
312_E329_R0.5640.29
55_E72_D0.5640.29
54_E517_K0.5640.29
88_F177_S0.5640.29
415_P431_I0.5630.29
482_I526_V0.5630.29
324_S504_G0.5620.29
130_Q222_E0.5620.29
503_N506_G0.5610.29
493_T523_A0.5610.29
423_V430_I0.5600.29
37_R46_L0.5600.29
525_A528_K0.5600.29
498_S503_N0.5590.29
425_A458_I0.5570.29
261_R530_A0.5570.29
223_Y252_N0.5570.29
444_S467_F0.5560.29
82_D120_R0.5560.29
86_T557_Y0.5550.29
476_A548_I0.5550.29
531_Q544_L0.5550.29
444_S519_S0.5540.29
58_E62_I0.5540.29
89_Y173_I0.5540.29
327_A428_Q0.5530.29
127_I137_D0.5530.29
59_R297_K0.5530.29
330_Q357_Q0.5520.29
259_R299_V0.5520.29
174_G461_C0.5490.28
124_G446_F0.5470.28
195_L291_G0.5460.28
378_V428_Q0.5450.28
176_L190_T0.5450.28
64_Y91_L0.5450.28
291_G384_D0.5440.28
493_T496_Q0.5440.28
105_T267_F0.5440.28
245_F334_M0.5420.28
401_I429_D0.5420.28
319_Q328_A0.5410.28
180_T448_P0.5410.28
486_M533_Q0.5390.28
497_Y518_V0.5390.28
494_L525_A0.5390.28
271_I305_S0.5390.28
98_E473_G0.5390.28
200_N313_M0.5380.28
67_F70_E0.5380.28
512_L519_S0.5380.28
474_V477_S0.5370.27
344_K353_T0.5370.27
238_W288_A0.5360.27
134_N137_D0.5350.27
84_N87_L0.5350.27
44_G141_N0.5350.27
250_Q465_F0.5340.27
283_I492_E0.5340.27
148_K551_N0.5330.27
248_F445_P0.5320.27
143_P229_E0.5320.27
418_N463_N0.5320.27
16_A19_V0.5310.27
105_T418_N0.5300.27
51_E115_F0.5300.27
319_Q322_G0.5290.27
517_K520_R0.5290.27
251_K255_P0.5280.27
256_L465_F0.5270.27
24_P452_K0.5270.27
54_E240_D0.5270.27
80_I142_V0.5270.27
338_F392_Q0.5270.27
16_A40_F0.5260.27
133_H195_L0.5260.27
200_N326_E0.5260.27
316_S484_D0.5250.27
114_R414_M0.5250.27
108_V242_L0.5250.27
502_L505_E0.5220.26
116_S487_L0.5220.26
431_I438_A0.5210.26
512_L515_I0.5210.26
23_F38_R0.5210.26
486_M522_I0.5200.26
86_T238_W0.5200.26
96_L556_E0.5190.26
415_P425_A0.5180.26
431_I449_V0.5180.26
225_E376_D0.5180.26
108_V112_C0.5180.26
54_E58_E0.5180.26
416_L423_V0.5170.26
30_S41_N0.5170.26
129_Y195_L0.5160.26
334_M341_L0.5160.26
41_N146_N0.5150.26
113_E467_F0.5140.26
77_L80_I0.5140.26
58_E208_P0.5140.26
94_N98_E0.5140.26
34_M43_L0.5130.26
55_E214_R0.5130.26
376_D399_E0.5130.26
201_N337_R0.5130.26
116_S470_I0.5120.26
489_S529_M0.5120.26
58_E69_T0.5110.26
217_R223_Y0.5110.26
57_A95_H0.5110.26
142_V229_E0.5110.26
534_G548_I0.5110.26
157_R275_A0.5100.26
454_K506_G0.5100.26
298_I553_W0.5090.26
322_G328_A0.5090.26
261_R414_M0.5090.26
80_I209_L0.5080.25
487_L490_A0.5080.25
286_S289_A0.5080.25
159_L171_I0.5070.25
300_F334_M0.5070.25
209_L525_A0.5060.25
275_A474_V0.5060.25
526_V530_A0.5060.25
320_R485_E0.5050.25
290_G500_L0.5050.25
99_M494_L0.5050.25
343_D353_T0.5040.25
423_V444_S0.5040.25
34_M50_V0.5040.25
76_Y513_K0.5030.25
244_Q250_Q0.5030.25
290_G330_Q0.5020.25
142_V440_V0.5020.25
93_N200_N0.5020.25
113_E167_G0.5020.25
223_Y248_F0.5020.25
75_I215_N0.5010.25
353_T542_E0.5010.25
129_Y197_V0.5000.25
336_D345_M0.5000.25
347_N469_G0.5000.25
105_T445_P0.5000.25
83_T193_V0.5000.25
421_S444_S0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1gq2A 6 0.9593 100 0.145 Contact Map
1o0sA 4 0.9841 100 0.146 Contact Map
1pj3A 4 0.9664 100 0.149 Contact Map
3nv9A 2 0.7965 100 0.536 Contact Map
1vl6A 4 0.6354 100 0.608 Contact Map
2a9fA 2 0.669 100 0.66 Contact Map
2dvmA 2 0.7292 100 0.67 Contact Map
4ppmA 2 0.0407 99.3 0.945 Contact Map
1v8bA 4 0.7398 99 0.952 Contact Map
3aoeE 3 0.6549 98.5 0.961 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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