GREMLIN Database
LIGB - DNA ligase B
UniProt: P25772 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11334
Length: 560 (525)
Sequences: 4328 (2745)
Seq/√Len: 119.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
33_E67_R5.8571.00
315_K334_A4.4671.00
44_W56_V3.7241.00
113_M119_L3.4191.00
452_L480_A3.3691.00
142_A158_V3.3141.00
43_Q47_D3.1971.00
118_D284_A3.1921.00
47_D55_E3.1521.00
252_R266_E3.1401.00
326_K401_T3.1381.00
516_T519_F3.1261.00
353_R356_E3.0091.00
46_D51_E2.9351.00
453_L549_W2.9161.00
313_E334_A2.8691.00
313_E364_Q2.8091.00
43_Q55_E2.7791.00
30_A75_F2.7101.00
455_T458_Q2.7021.00
138_K167_T2.6311.00
103_M301_V2.5261.00
385_A388_T2.5111.00
471_A475_H2.5061.00
316_A361_P2.4291.00
510_S551_A2.3791.00
34_I71_W2.3691.00
318_Q332_S2.3361.00
46_D50_K2.3141.00
113_M117_S2.3091.00
135_R174_N2.2961.00
309_A368_S2.2801.00
351_V355_Q2.2621.00
135_R140_N2.2491.00
478_N481_R2.2431.00
517_E532_R2.2381.00
40_Q44_W2.1981.00
44_W47_D2.1581.00
456_P471_A2.1381.00
186_E273_P2.1341.00
70_Q74_C2.1071.00
256_N259_E2.0911.00
36_R40_Q2.0911.00
456_P474_W2.0881.00
447_H549_W2.0861.00
110_S258_D2.0711.00
548_S552_A2.0671.00
513_L544_K2.0531.00
139_L158_V2.0411.00
426_L452_L2.0191.00
231_L284_A2.0121.00
332_S345_R2.0071.00
453_L553_Q2.0061.00
341_K369_L1.9981.00
535_I539_E1.9981.00
34_I38_Q1.9881.00
33_E36_R1.9731.00
41_I45_D1.9471.00
130_V154_W1.9421.00
238_E242_A1.9161.00
184_Q187_G1.9021.00
513_L548_S1.8661.00
185_R275_V1.8531.00
233_S253_A1.8481.00
230_Q234_D1.8381.00
414_I437_R1.8361.00
38_Q79_P1.8301.00
118_D255_K1.8181.00
133_V141_K1.8151.00
44_W64_L1.8111.00
233_S237_K1.8011.00
31_Q35_S1.7981.00
253_A284_A1.7921.00
187_G217_S1.7851.00
196_I337_M1.7801.00
254_V259_E1.7731.00
424_Q499_A1.7711.00
69_T84_M1.7681.00
319_F327_I1.7591.00
366_L379_D1.7541.00
106_K265_N1.7471.00
368_S376_R1.7421.00
456_P460_Q1.7391.00
415_S418_V1.7291.00
341_K373_G1.7261.00
66_A69_T1.6991.00
163_A219_G1.6881.00
106_K261_A1.6731.00
100_V300_L1.6711.00
57_E60_V1.6701.00
233_S284_A1.6641.00
111_L114_R1.6631.00
159_S166_Q1.6601.00
431_I473_L1.6561.00
132_L164_V1.6421.00
496_L533_Q1.6401.00
367_V377_I1.6381.00
247_T274_F1.5961.00
316_A332_S1.5901.00
360_A390_P1.5881.00
91_V141_K1.5751.00
219_G245_T1.5671.00
333_L365_I1.5611.00
90_A427_G1.5551.00
92_M150_K1.5511.00
34_I78_E1.5481.00
133_V174_N1.5471.00
47_D51_E1.5411.00
501_L530_R1.5321.00
205_L214_T1.5311.00
369_L373_G1.5251.00
66_A108_A1.5211.00
65_S69_T1.5201.00
260_V281_V1.5171.00
125_V182_F1.5151.00
320_A330_V1.5111.00
42_K45_D1.5041.00
517_E535_I1.4981.00
34_I68_L1.4961.00
101_R296_Q1.4841.00
158_V181_I1.4841.00
419_W490_M1.4631.00
130_V158_V1.4581.00
116_R283_A1.4401.00
417_L436_W1.4321.00
47_D53_K1.4281.00
103_M108_A1.4251.00
261_A265_N1.4111.00
541_A545_K1.4091.00
189_I193_M1.4081.00
125_V221_F1.4071.00
311_V364_Q1.4011.00
497_T530_R1.3931.00
110_S261_A1.3861.00
508_S511_Q1.3831.00
158_V161_I1.3791.00
106_K110_S1.3791.00
470_S474_W1.3721.00
182_F219_G1.3721.00
517_E521_Q1.3681.00
335_P342_K1.3671.00
435_G465_I1.3661.00
467_K471_A1.3561.00
110_S257_A1.3531.00
311_V383_R1.3471.00
86_P166_Q1.3461.00
238_E241_T1.3451.00
183_L191_Q1.3411.00
258_D262_R1.3411.00
234_D237_K1.3391.00
69_T73_R1.3351.00
92_M149_L1.3281.00
190_Q194_G1.3261.00
90_A150_K1.3191.00
187_G190_Q1.3131.00
360_A388_T1.3101.00
105_D108_A1.3081.00
130_V220_V1.3081.00
40_Q43_Q1.3001.00
267_W279_V1.3001.00
437_R441_Q1.2991.00
230_Q285_K1.2951.00
164_V220_V1.2911.00
34_I84_M1.2901.00
513_L538_K1.2891.00
426_L483_Q1.2801.00
485_F503_A1.2801.00
548_S551_A1.2791.00
468_S472_Q1.2681.00
47_D56_V1.2580.99
262_R265_N1.2570.99
513_L547_G1.2550.99
276_T372_Q1.2440.99
239_L244_F1.2350.99
506_E515_S1.2340.99
44_W54_S1.2330.99
270_A308_V1.2290.99
517_E528_S1.2220.99
184_Q219_G1.2200.99
428_L477_F1.2190.99
255_K259_E1.2190.99
39_Q43_Q1.2160.99
94_P133_V1.2120.99
449_F549_W1.2100.99
281_V303_W1.2060.99
113_M257_A1.2040.99
426_L480_A1.1970.99
414_I440_H1.1940.99
44_W55_E1.1930.99
160_L215_L1.1910.99
485_F489_V1.1880.99
506_E523_L1.1870.99
532_R536_E1.1860.99
66_A70_Q1.1840.99
357_W376_R1.1820.99
98_T292_W1.1790.99
456_P467_K1.1770.99
468_S471_A1.1760.99
412_Q416_R1.1690.99
449_F546_L1.1670.99
545_K549_W1.1650.99
121_V254_V1.1650.99
425_V490_M1.1640.99
414_I441_Q1.1560.99
183_L187_G1.1550.99
474_W478_N1.1530.99
355_Q390_P1.1530.99
118_D253_A1.1510.99
420_L426_L1.1490.99
158_V164_V1.1480.99
438_A462_T1.1470.99
65_S295_G1.1460.99
45_D86_P1.1420.99
544_K548_S1.1400.99
35_S39_Q1.1370.99
394_E411_E1.1360.99
311_V381_V1.1340.99
421_G431_I1.1290.99
549_W553_Q1.1270.99
139_L155_T1.1230.99
443_H446_E1.1220.99
511_Q519_F1.1200.99
231_L234_D1.1140.99
33_E40_Q1.1110.99
364_Q383_R1.1050.99
513_L551_A1.1010.99
121_V263_V1.1010.99
123_P263_V1.1000.99
394_E410_Q1.0990.99
259_E262_R1.0980.99
520_W534_V1.0960.99
94_P174_N1.0960.99
237_K251_T1.0920.99
265_N268_W1.0870.98
123_P267_W1.0860.98
465_I469_K1.0850.98
505_D519_F1.0740.98
40_Q64_L1.0720.98
496_L529_G1.0700.98
330_V345_R1.0700.98
368_S378_D1.0660.98
352_R400_L1.0610.98
337_M342_K1.0590.98
237_K240_A1.0580.98
118_D285_K1.0550.98
463_P469_K1.0550.98
475_H479_L1.0530.98
32_E36_R1.0480.98
139_L164_V1.0470.98
323_K493_G1.0450.98
459_L474_W1.0420.98
312_A333_L1.0410.98
56_V60_V1.0410.98
310_Q338_L1.0390.98
456_P470_S1.0380.98
120_W233_S1.0340.98
79_P85_P1.0310.98
94_P227_D1.0290.98
221_F274_F1.0290.98
351_V402_C1.0260.98
537_W543_I1.0250.98
531_A535_I1.0240.98
262_R266_E1.0240.98
208_R213_D1.0190.98
240_A251_T1.0180.98
343_V373_G1.0150.98
45_D65_S1.0150.98
394_E414_I1.0140.98
311_V366_L1.0140.98
141_K153_D1.0130.98
314_V380_V1.0110.98
421_G473_L1.0060.97
168_V244_F1.0060.97
309_A379_D1.0040.97
316_A389_K1.0040.97
489_V512_L1.0030.97
142_A164_V1.0030.97
38_Q42_K1.0020.97
444_R458_Q0.9990.97
366_L381_V0.9970.97
52_G203_A0.9970.97
464_G469_K0.9950.97
370_A376_R0.9940.97
97_H131_T0.9920.97
417_L451_W0.9920.97
333_L367_V0.9910.97
188_H198_A0.9870.97
309_A366_L0.9860.97
339_D369_L0.9840.97
331_A346_V0.9840.97
182_F221_F0.9780.97
458_Q461_N0.9770.97
519_F522_Q0.9750.97
102_K296_Q0.9670.97
168_V172_L0.9670.97
439_L459_L0.9640.97
496_L530_R0.9630.97
506_E519_F0.9620.97
56_V64_L0.9620.97
418_V433_E0.9580.97
190_Q193_M0.9540.96
403_Y495_P0.9510.96
107_N111_L0.9470.96
510_S514_F0.9450.96
75_F78_E0.9440.96
521_Q528_S0.9410.96
187_G219_G0.9410.96
177_L239_L0.9400.96
421_G436_W0.9390.96
417_L445_F0.9380.96
60_V63_Q0.9370.96
445_F450_S0.9370.96
225_W235_R0.9350.96
257_A261_A0.9330.96
399_S495_P0.9310.96
528_S532_R0.9280.96
224_A287_P0.9270.96
130_V181_I0.9240.96
479_L482_K0.9240.96
34_I79_P0.9170.96
71_W78_E0.9140.96
293_L296_Q0.9130.95
120_W232_M0.9100.95
290_R298_E0.9080.95
283_A290_R0.9080.95
59_G63_Q0.9080.95
163_A245_T0.9070.95
240_A248_Q0.9060.95
257_A260_V0.9050.95
45_D61_Y0.9040.95
39_Q42_K0.9020.95
233_S251_T0.9020.95
536_E540_N0.8980.95
447_H546_L0.8940.95
237_K241_T0.8930.95
460_Q466_A0.8890.95
121_V260_V0.8880.95
32_E35_S0.8870.95
357_W380_V0.8850.95
353_R357_W0.8840.95
510_S513_L0.8830.95
366_L378_D0.8820.95
152_E207_M0.8810.95
174_N227_D0.8810.95
358_D384_G0.8770.94
479_L483_Q0.8770.94
505_D522_Q0.8750.94
483_Q487_R0.8750.94
107_N110_S0.8730.94
212_S215_L0.8700.94
121_V281_V0.8690.94
451_W477_F0.8660.94
40_Q56_V0.8610.94
72_Q82_V0.8610.94
379_D382_W0.8560.94
125_V247_T0.8550.94
30_A78_E0.8550.94
420_L452_L0.8540.94
156_Q214_T0.8530.94
485_F512_L0.8530.94
254_V260_V0.8500.93
187_G191_Q0.8450.93
131_T226_P0.8450.93
317_I360_A0.8440.93
68_L79_P0.8420.93
236_L246_L0.8350.93
413_F440_H0.8320.93
314_V379_D0.8320.93
109_L264_R0.8310.93
154_W181_I0.8310.93
42_K81_D0.8300.93
181_I206_M0.8290.93
501_L526_T0.8290.93
431_I451_W0.8280.93
222_V244_F0.8250.92
425_V491_A0.8240.92
109_L281_V0.8230.92
122_Q282_R0.8200.92
448_I546_L0.8190.92
506_E520_W0.8150.92
100_V280_V0.8130.92
264_R303_W0.8120.92
94_P141_K0.8100.92
438_A463_P0.8060.91
35_S38_Q0.8050.91
318_Q330_V0.8050.91
263_V266_E0.8040.91
172_L242_A0.8020.91
70_Q73_R0.8010.91
132_L142_A0.8000.91
321_V327_I0.7970.91
407_D540_N0.7940.91
438_A464_G0.7940.91
482_K556_T0.7930.91
355_Q400_L0.7930.91
81_D167_T0.7930.91
202_V218_L0.7930.91
520_W526_T0.7900.91
119_L281_V0.7880.91
539_E544_K0.7870.90
91_V153_D0.7870.90
181_I218_L0.7860.90
542_Q545_K0.7850.90
128_V202_V0.7850.90
460_Q470_S0.7850.90
36_R67_R0.7850.90
384_G389_K0.7850.90
29_R32_E0.7850.90
309_A378_D0.7810.90
29_R75_F0.7790.90
363_D384_G0.7790.90
287_P299_W0.7740.90
469_K472_Q0.7730.90
129_A223_W0.7730.90
185_R273_P0.7710.90
113_M260_V0.7710.90
190_Q217_S0.7700.90
175_S239_L0.7690.89
540_N543_I0.7670.89
94_P131_T0.7650.89
511_Q514_F0.7650.89
440_H445_F0.7650.89
72_Q83_M0.7620.89
252_R263_V0.7620.89
465_I470_S0.7600.89
338_L373_G0.7590.89
444_R462_T0.7560.89
408_V542_Q0.7560.89
422_A425_V0.7540.89
252_R259_E0.7540.89
396_R399_S0.7510.88
268_W306_Q0.7490.88
206_M214_T0.7490.88
72_Q84_M0.7480.88
132_L139_L0.7460.88
109_L260_V0.7460.88
92_M143_I0.7450.88
314_V365_I0.7450.88
121_V279_V0.7440.88
417_L448_I0.7440.88
95_V227_D0.7440.88
120_W236_L0.7420.88
240_A246_L0.7410.88
472_Q475_H0.7390.88
386_E389_K0.7380.87
232_M287_P0.7370.87
113_M116_R0.7360.87
33_E71_W0.7310.87
438_A465_I0.7310.87
445_F451_W0.7300.87
460_Q467_K0.7280.87
364_Q381_V0.7270.87
34_I75_F0.7270.87
419_W425_V0.7240.86
347_N373_G0.7220.86
460_Q474_W0.7210.86
545_K548_S0.7160.86
439_L443_H0.7150.86
286_E289_S0.7140.86
294_P500_A0.7140.86
507_R511_Q0.7120.86
339_D372_Q0.7120.86
66_A103_M0.7110.85
358_D382_W0.7110.85
359_I380_V0.7090.85
392_P404_F0.7090.85
525_G530_R0.7080.85
65_S84_M0.7070.85
160_L214_T0.7060.85
170_G238_E0.7050.85
318_Q345_R0.7050.85
80_R138_K0.7040.85
310_Q367_V0.7000.85
268_W305_Y0.7000.85
116_R290_R0.6990.84
139_L142_A0.6990.84
433_E437_R0.6970.84
505_D523_L0.6960.84
514_F544_K0.6940.84
80_R85_P0.6940.84
338_L341_K0.6920.84
168_V171_P0.6920.84
513_L516_T0.6890.84
384_G388_T0.6890.84
549_W552_A0.6880.84
191_Q217_S0.6870.83
260_V303_W0.6860.83
186_E190_Q0.6850.83
191_Q201_K0.6830.83
459_L470_S0.6820.83
305_Y372_Q0.6810.83
109_L303_W0.6800.83
135_R141_K0.6770.83
119_L257_A0.6770.83
66_A102_K0.6760.82
442_T462_T0.6760.82
57_E311_V0.6760.82
162_S166_Q0.6760.82
169_S172_L0.6750.82
175_S242_A0.6740.82
210_D216_N0.6740.82
488_W491_A0.6720.82
501_L525_G0.6700.82
319_F351_V0.6700.82
109_L113_M0.6690.82
102_K301_V0.6690.82
46_D169_S0.6660.82
129_A224_A0.6660.82
497_T534_V0.6660.82
120_W251_T0.6650.81
30_A74_C0.6640.81
435_G473_L0.6620.81
191_Q195_G0.6620.81
481_R554_Q0.6610.81
222_V246_L0.6610.81
38_Q68_L0.6570.81
196_I342_K0.6570.81
43_Q56_V0.6560.81
263_V279_V0.6560.81
392_P395_N0.6560.81
408_V413_F0.6540.80
483_Q488_W0.6530.80
338_L367_V0.6520.80
103_M109_L0.6510.80
69_T101_R0.6510.80
464_G470_S0.6510.80
111_L115_E0.6500.80
50_K89_G0.6480.80
426_L491_A0.6480.80
484_P556_T0.6470.80
156_Q211_D0.6440.79
264_R279_V0.6440.79
236_L251_T0.6440.79
31_Q78_E0.6440.79
429_D479_L0.6430.79
438_A442_T0.6410.79
161_I164_V0.6410.79
221_F247_T0.6390.79
395_N404_F0.6390.79
315_K318_Q0.6390.79
512_L538_K0.6380.79
186_E189_I0.6360.78
162_S215_L0.6340.78
355_Q358_D0.6330.78
478_N482_K0.6320.78
118_D231_L0.6320.78
485_F509_W0.6320.78
211_D215_L0.6310.78
505_D511_Q0.6300.78
488_W555_I0.6300.78
264_R268_W0.6300.78
67_R70_Q0.6290.78
97_H143_I0.6290.78
546_L549_W0.6290.78
521_Q535_I0.6290.78
416_R537_W0.6280.78
326_K400_L0.6270.78
395_N411_E0.6260.77
434_A437_R0.6260.77
68_L83_M0.6260.77
225_W239_L0.6240.77
68_L71_W0.6240.77
361_P388_T0.6220.77
136_D174_N0.6210.77
41_I68_L0.6200.77
448_I491_A0.6200.77
541_A544_K0.6200.77
183_L217_S0.6180.76
488_W509_W0.6180.76
472_Q476_Q0.6170.76
331_A377_I0.6170.76
132_L244_F0.6160.76
360_A389_K0.6140.76
475_H478_N0.6130.76
235_R239_L0.6120.76
326_K403_Y0.6120.76
205_L208_R0.6120.76
276_T305_Y0.6110.76
97_H129_A0.6110.76
258_D261_A0.6110.76
68_L84_M0.6100.76
112_W525_G0.6090.75
414_I436_W0.6090.75
43_Q46_D0.6080.75
131_T176_T0.6070.75
221_F272_L0.6070.75
530_R533_Q0.6050.75
232_M235_R0.6050.75
460_Q471_A0.6040.75
123_P279_V0.6020.75
139_L166_Q0.6020.75
30_A33_E0.6010.74
50_K163_A0.6010.74
315_K332_S0.6000.74
395_N406_S0.6000.74
364_Q385_A0.5980.74
453_L552_A0.5980.74
361_P389_K0.5980.74
150_K487_R0.5980.74
162_S217_S0.5970.74
509_W513_L0.5970.74
49_W65_S0.5960.74
163_A182_F0.5960.74
495_P533_Q0.5950.74
261_A264_R0.5950.74
320_A332_S0.5940.74
454_L474_W0.5930.74
483_Q556_T0.5930.74
421_G428_L0.5930.74
464_G525_G0.5930.74
232_M236_L0.5920.73
501_L534_V0.5900.73
347_N376_R0.5890.73
457_E460_Q0.5880.73
170_G242_A0.5870.73
547_G551_A0.5840.72
424_Q490_M0.5830.72
523_L526_T0.5830.72
160_L217_S0.5830.72
132_L158_V0.5800.72
205_L216_N0.5790.72
434_A438_A0.5790.72
196_I339_D0.5790.72
385_A389_K0.5790.72
476_Q479_L0.5780.72
488_W551_A0.5780.72
110_S114_R0.5780.72
268_W276_T0.5760.71
420_L555_I0.5750.71
360_A386_E0.5750.71
86_P163_A0.5740.71
275_V308_V0.5740.71
41_I65_S0.5720.71
511_Q515_S0.5720.71
382_W385_A0.5720.71
169_S244_F0.5710.71
40_Q67_R0.5710.71
221_F246_L0.5700.71
169_S241_T0.5690.70
413_F416_R0.5680.70
542_Q546_L0.5680.70
426_L555_I0.5680.70
435_G469_K0.5680.70
488_W550_L0.5670.70
455_T470_S0.5670.70
270_A276_T0.5660.70
154_W158_V0.5650.70
453_L457_E0.5650.70
131_T143_I0.5640.70
147_N150_K0.5630.70
509_W551_A0.5630.70
521_Q526_T0.5620.70
33_E64_L0.5620.70
455_T478_N0.5620.70
133_V143_I0.5620.70
104_V207_M0.5620.70
420_L448_I0.5610.69
91_V143_I0.5610.69
57_E63_Q0.5610.69
104_V368_S0.5610.69
195_G209_Q0.5600.69
61_Y65_S0.5590.69
337_M341_K0.5590.69
439_L451_W0.5590.69
407_D537_W0.5590.69
101_R301_V0.5590.69
268_W372_Q0.5570.69
506_E512_L0.5570.69
418_V436_W0.5560.69
42_K86_P0.5560.69
413_F417_L0.5560.69
86_P160_L0.5560.69
386_E390_P0.5550.69
343_V367_V0.5550.69
418_V437_R0.5550.69
353_R359_I0.5550.69
427_G483_Q0.5540.68
439_L442_T0.5540.68
442_T463_P0.5530.68
526_T534_V0.5520.68
208_R214_T0.5520.68
491_A503_A0.5520.68
142_A154_W0.5520.68
174_N226_P0.5510.68
263_V267_W0.5510.68
109_L257_A0.5500.68
195_G345_R0.5500.68
115_E298_E0.5500.68
156_Q159_S0.5500.68
182_F245_T0.5490.68
462_T465_I0.5490.68
448_I550_L0.5490.68
164_V245_T0.5480.68
113_M256_N0.5470.67
347_N353_R0.5470.67
357_W360_A0.5470.67
382_W386_E0.5460.67
529_G532_R0.5460.67
102_K108_A0.5450.67
54_S203_A0.5440.67
320_A328_S0.5440.67
319_F402_C0.5440.67
45_D49_W0.5440.67
38_Q81_D0.5430.67
446_E450_S0.5430.67
144_S154_W0.5420.67
30_A34_I0.5420.67
339_D373_G0.5420.67
384_G387_R0.5410.67
358_D389_K0.5410.67
52_G207_M0.5410.67
177_L244_F0.5400.66
447_H545_K0.5400.66
170_G241_T0.5400.66
192_Q209_Q0.5390.66
544_K547_G0.5380.66
104_V264_R0.5380.66
327_I351_V0.5380.66
226_P235_R0.5370.66
436_W473_L0.5370.66
526_T530_R0.5370.66
59_G307_P0.5360.66
276_T373_G0.5350.66
509_W512_L0.5350.66
488_W556_T0.5350.66
97_H176_T0.5350.66
184_Q201_K0.5350.66
213_D216_N0.5350.66
449_F553_Q0.5320.65
223_W274_F0.5320.65
185_R189_I0.5310.65
34_I77_S0.5310.65
255_K284_A0.5310.65
423_K429_D0.5310.65
219_G222_V0.5300.65
63_Q310_Q0.5300.65
44_W57_E0.5300.65
156_Q206_M0.5300.65
181_I202_V0.5290.65
543_I546_L0.5290.65
267_W276_T0.5280.65
398_N401_T0.5280.65
500_A525_G0.5270.65
497_T501_L0.5270.65
420_L491_A0.5250.64
208_R370_A0.5250.64
71_W74_C0.5250.64
351_V400_L0.5250.64
252_R262_R0.5220.64
288_E292_W0.5220.64
516_T534_V0.5220.64
282_R299_W0.5220.64
279_V305_Y0.5210.64
182_F274_F0.5210.64
465_I473_L0.5200.64
481_R553_Q0.5200.64
484_P488_W0.5190.63
104_V306_Q0.5180.63
364_Q384_G0.5150.63
320_A345_R0.5130.63
490_M499_A0.5130.63
458_Q466_A0.5120.62
442_T461_N0.5110.62
463_P466_A0.5110.62
360_A382_W0.5110.62
520_W525_G0.5100.62
283_A286_E0.5100.62
538_K547_G0.5100.62
209_Q346_V0.5100.62
121_V267_W0.5090.62
404_F409_C0.5090.62
352_R355_Q0.5090.62
425_V487_R0.5080.62
220_V245_T0.5060.62
133_V227_D0.5060.62
439_L473_L0.5060.62
83_M86_P0.5050.61
101_R293_L0.5050.61
167_T171_P0.5050.61
405_A540_N0.5040.61
462_T466_A0.5040.61
207_M370_A0.5030.61
31_Q75_F0.5030.61
50_K215_L0.5030.61
68_L72_Q0.5020.61
40_Q47_D0.5010.61
225_W228_G0.5010.61
175_S228_G0.5000.61
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3sgiA 1 0.65 100 0.083 Contact Map
2owoA 1 0.9518 100 0.091 Contact Map
1dgsA 1 0.9482 100 0.099 Contact Map
4glxA 1 0.9429 100 0.141 Contact Map
3uq8A 1 0.5071 100 0.511 Contact Map
1zauA 1 0.5054 100 0.515 Contact Map
3jslA 2 0.4946 100 0.516 Contact Map
4lh6A 1 0.5179 100 0.519 Contact Map
1b04A 1 0.5036 100 0.525 Contact Map
4glwA 2 0.4518 100 0.533 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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