LIGB - ECOLI - GREMLIN Contacts

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LIGB - DNA ligase B

UniProt:	P25772	Sequences: MKVWMAILIGILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQWDDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRKMVDKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSLISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSLGVFVWAWPDGPQLMSDRLKELATAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVTDGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTPPENRFNSLTCYFASDVCQEQFISRLVWLGAKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTPGIAKSKSAQLWHQFNLARKQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11334
Length:	560 (525)
Sequences:	4328 (2745)
Seq/√Len:	119.8

ECOLI - LIGB DNLJ
BACSU - DNLJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
33_E	67_R	5.857	1.00
315_K	334_A	4.467	1.00
44_W	56_V	3.724	1.00
113_M	119_L	3.419	1.00
452_L	480_A	3.369	1.00
142_A	158_V	3.314	1.00
43_Q	47_D	3.197	1.00
118_D	284_A	3.192	1.00
47_D	55_E	3.152	1.00
252_R	266_E	3.140	1.00
326_K	401_T	3.138	1.00
516_T	519_F	3.126	1.00
353_R	356_E	3.009	1.00
46_D	51_E	2.935	1.00
453_L	549_W	2.916	1.00
313_E	334_A	2.869	1.00
313_E	364_Q	2.809	1.00
43_Q	55_E	2.779	1.00
30_A	75_F	2.710	1.00
455_T	458_Q	2.702	1.00
138_K	167_T	2.631	1.00
103_M	301_V	2.526	1.00
385_A	388_T	2.511	1.00
471_A	475_H	2.506	1.00
316_A	361_P	2.429	1.00
510_S	551_A	2.379	1.00
34_I	71_W	2.369	1.00
318_Q	332_S	2.336	1.00
46_D	50_K	2.314	1.00
113_M	117_S	2.309	1.00
135_R	174_N	2.296	1.00
309_A	368_S	2.280	1.00
351_V	355_Q	2.262	1.00
135_R	140_N	2.249	1.00
478_N	481_R	2.243	1.00
517_E	532_R	2.238	1.00
40_Q	44_W	2.198	1.00
44_W	47_D	2.158	1.00
456_P	471_A	2.138	1.00
186_E	273_P	2.134	1.00
70_Q	74_C	2.107	1.00
256_N	259_E	2.091	1.00
36_R	40_Q	2.091	1.00
456_P	474_W	2.088	1.00
447_H	549_W	2.086	1.00
110_S	258_D	2.071	1.00
548_S	552_A	2.067	1.00
513_L	544_K	2.053	1.00
139_L	158_V	2.041	1.00
426_L	452_L	2.019	1.00
231_L	284_A	2.012	1.00
332_S	345_R	2.007	1.00
453_L	553_Q	2.006	1.00
341_K	369_L	1.998	1.00
535_I	539_E	1.998	1.00
34_I	38_Q	1.988	1.00
33_E	36_R	1.973	1.00
41_I	45_D	1.947	1.00
130_V	154_W	1.942	1.00
238_E	242_A	1.916	1.00
184_Q	187_G	1.902	1.00
513_L	548_S	1.866	1.00
185_R	275_V	1.853	1.00
233_S	253_A	1.848	1.00
230_Q	234_D	1.838	1.00
414_I	437_R	1.836	1.00
38_Q	79_P	1.830	1.00
118_D	255_K	1.818	1.00
133_V	141_K	1.815	1.00
44_W	64_L	1.811	1.00
233_S	237_K	1.801	1.00
31_Q	35_S	1.798	1.00
253_A	284_A	1.792	1.00
187_G	217_S	1.785	1.00
196_I	337_M	1.780	1.00
254_V	259_E	1.773	1.00
424_Q	499_A	1.771	1.00
69_T	84_M	1.768	1.00
319_F	327_I	1.759	1.00
366_L	379_D	1.754	1.00
106_K	265_N	1.747	1.00
368_S	376_R	1.742	1.00
456_P	460_Q	1.739	1.00
415_S	418_V	1.729	1.00
341_K	373_G	1.726	1.00
66_A	69_T	1.699	1.00
163_A	219_G	1.688	1.00
106_K	261_A	1.673	1.00
100_V	300_L	1.671	1.00
57_E	60_V	1.670	1.00
233_S	284_A	1.664	1.00
111_L	114_R	1.663	1.00
159_S	166_Q	1.660	1.00
431_I	473_L	1.656	1.00
132_L	164_V	1.642	1.00
496_L	533_Q	1.640	1.00
367_V	377_I	1.638	1.00
247_T	274_F	1.596	1.00
316_A	332_S	1.590	1.00
360_A	390_P	1.588	1.00
91_V	141_K	1.575	1.00
219_G	245_T	1.567	1.00
333_L	365_I	1.561	1.00
90_A	427_G	1.555	1.00
92_M	150_K	1.551	1.00
34_I	78_E	1.548	1.00
133_V	174_N	1.547	1.00
47_D	51_E	1.541	1.00
501_L	530_R	1.532	1.00
205_L	214_T	1.531	1.00
369_L	373_G	1.525	1.00
66_A	108_A	1.521	1.00
65_S	69_T	1.520	1.00
260_V	281_V	1.517	1.00
125_V	182_F	1.515	1.00
320_A	330_V	1.511	1.00
42_K	45_D	1.504	1.00
517_E	535_I	1.498	1.00
34_I	68_L	1.496	1.00
101_R	296_Q	1.484	1.00
158_V	181_I	1.484	1.00
419_W	490_M	1.463	1.00
130_V	158_V	1.458	1.00
116_R	283_A	1.440	1.00
417_L	436_W	1.432	1.00
47_D	53_K	1.428	1.00
103_M	108_A	1.425	1.00
261_A	265_N	1.411	1.00
541_A	545_K	1.409	1.00
189_I	193_M	1.408	1.00
125_V	221_F	1.407	1.00
311_V	364_Q	1.401	1.00
497_T	530_R	1.393	1.00
110_S	261_A	1.386	1.00
508_S	511_Q	1.383	1.00
158_V	161_I	1.379	1.00
106_K	110_S	1.379	1.00
470_S	474_W	1.372	1.00
182_F	219_G	1.372	1.00
517_E	521_Q	1.368	1.00
335_P	342_K	1.367	1.00
435_G	465_I	1.366	1.00
467_K	471_A	1.356	1.00
110_S	257_A	1.353	1.00
311_V	383_R	1.347	1.00
86_P	166_Q	1.346	1.00
238_E	241_T	1.345	1.00
183_L	191_Q	1.341	1.00
258_D	262_R	1.341	1.00
234_D	237_K	1.339	1.00
69_T	73_R	1.335	1.00
92_M	149_L	1.328	1.00
190_Q	194_G	1.326	1.00
90_A	150_K	1.319	1.00
187_G	190_Q	1.313	1.00
360_A	388_T	1.310	1.00
105_D	108_A	1.308	1.00
130_V	220_V	1.308	1.00
40_Q	43_Q	1.300	1.00
267_W	279_V	1.300	1.00
437_R	441_Q	1.299	1.00
230_Q	285_K	1.295	1.00
164_V	220_V	1.291	1.00
34_I	84_M	1.290	1.00
513_L	538_K	1.289	1.00
426_L	483_Q	1.280	1.00
485_F	503_A	1.280	1.00
548_S	551_A	1.279	1.00
468_S	472_Q	1.268	1.00
47_D	56_V	1.258	0.99
262_R	265_N	1.257	0.99
513_L	547_G	1.255	0.99
276_T	372_Q	1.244	0.99
239_L	244_F	1.235	0.99
506_E	515_S	1.234	0.99
44_W	54_S	1.233	0.99
270_A	308_V	1.229	0.99
517_E	528_S	1.222	0.99
184_Q	219_G	1.220	0.99
428_L	477_F	1.219	0.99
255_K	259_E	1.219	0.99
39_Q	43_Q	1.216	0.99
94_P	133_V	1.212	0.99
449_F	549_W	1.210	0.99
281_V	303_W	1.206	0.99
113_M	257_A	1.204	0.99
426_L	480_A	1.197	0.99
414_I	440_H	1.194	0.99
44_W	55_E	1.193	0.99
160_L	215_L	1.191	0.99
485_F	489_V	1.188	0.99
506_E	523_L	1.187	0.99
532_R	536_E	1.186	0.99
66_A	70_Q	1.184	0.99
357_W	376_R	1.182	0.99
98_T	292_W	1.179	0.99
456_P	467_K	1.177	0.99
468_S	471_A	1.176	0.99
412_Q	416_R	1.169	0.99
449_F	546_L	1.167	0.99
545_K	549_W	1.165	0.99
121_V	254_V	1.165	0.99
425_V	490_M	1.164	0.99
414_I	441_Q	1.156	0.99
183_L	187_G	1.155	0.99
474_W	478_N	1.153	0.99
355_Q	390_P	1.153	0.99
118_D	253_A	1.151	0.99
420_L	426_L	1.149	0.99
158_V	164_V	1.148	0.99
438_A	462_T	1.147	0.99
65_S	295_G	1.146	0.99
45_D	86_P	1.142	0.99
544_K	548_S	1.140	0.99
35_S	39_Q	1.137	0.99
394_E	411_E	1.136	0.99
311_V	381_V	1.134	0.99
421_G	431_I	1.129	0.99
549_W	553_Q	1.127	0.99
139_L	155_T	1.123	0.99
443_H	446_E	1.122	0.99
511_Q	519_F	1.120	0.99
231_L	234_D	1.114	0.99
33_E	40_Q	1.111	0.99
364_Q	383_R	1.105	0.99
513_L	551_A	1.101	0.99
121_V	263_V	1.101	0.99
123_P	263_V	1.100	0.99
394_E	410_Q	1.099	0.99
259_E	262_R	1.098	0.99
520_W	534_V	1.096	0.99
94_P	174_N	1.096	0.99
237_K	251_T	1.092	0.99
265_N	268_W	1.087	0.98
123_P	267_W	1.086	0.98
465_I	469_K	1.085	0.98
505_D	519_F	1.074	0.98
40_Q	64_L	1.072	0.98
496_L	529_G	1.070	0.98
330_V	345_R	1.070	0.98
368_S	378_D	1.066	0.98
352_R	400_L	1.061	0.98
337_M	342_K	1.059	0.98
237_K	240_A	1.058	0.98
118_D	285_K	1.055	0.98
463_P	469_K	1.055	0.98
475_H	479_L	1.053	0.98
32_E	36_R	1.048	0.98
139_L	164_V	1.047	0.98
323_K	493_G	1.045	0.98
459_L	474_W	1.042	0.98
312_A	333_L	1.041	0.98
56_V	60_V	1.041	0.98
310_Q	338_L	1.039	0.98
456_P	470_S	1.038	0.98
120_W	233_S	1.034	0.98
79_P	85_P	1.031	0.98
94_P	227_D	1.029	0.98
221_F	274_F	1.029	0.98
351_V	402_C	1.026	0.98
537_W	543_I	1.025	0.98
531_A	535_I	1.024	0.98
262_R	266_E	1.024	0.98
208_R	213_D	1.019	0.98
240_A	251_T	1.018	0.98
343_V	373_G	1.015	0.98
45_D	65_S	1.015	0.98
394_E	414_I	1.014	0.98
311_V	366_L	1.014	0.98
141_K	153_D	1.013	0.98
314_V	380_V	1.011	0.98
421_G	473_L	1.006	0.97
168_V	244_F	1.006	0.97
309_A	379_D	1.004	0.97
316_A	389_K	1.004	0.97
489_V	512_L	1.003	0.97
142_A	164_V	1.003	0.97
38_Q	42_K	1.002	0.97
444_R	458_Q	0.999	0.97
366_L	381_V	0.997	0.97
52_G	203_A	0.997	0.97
464_G	469_K	0.995	0.97
370_A	376_R	0.994	0.97
97_H	131_T	0.992	0.97
417_L	451_W	0.992	0.97
333_L	367_V	0.991	0.97
188_H	198_A	0.987	0.97
309_A	366_L	0.986	0.97
339_D	369_L	0.984	0.97
331_A	346_V	0.984	0.97
182_F	221_F	0.978	0.97
458_Q	461_N	0.977	0.97
519_F	522_Q	0.975	0.97
102_K	296_Q	0.967	0.97
168_V	172_L	0.967	0.97
439_L	459_L	0.964	0.97
496_L	530_R	0.963	0.97
506_E	519_F	0.962	0.97
56_V	64_L	0.962	0.97
418_V	433_E	0.958	0.97
190_Q	193_M	0.954	0.96
403_Y	495_P	0.951	0.96
107_N	111_L	0.947	0.96
510_S	514_F	0.945	0.96
75_F	78_E	0.944	0.96
521_Q	528_S	0.941	0.96
187_G	219_G	0.941	0.96
177_L	239_L	0.940	0.96
421_G	436_W	0.939	0.96
417_L	445_F	0.938	0.96
60_V	63_Q	0.937	0.96
445_F	450_S	0.937	0.96
225_W	235_R	0.935	0.96
257_A	261_A	0.933	0.96
399_S	495_P	0.931	0.96
528_S	532_R	0.928	0.96
224_A	287_P	0.927	0.96
130_V	181_I	0.924	0.96
479_L	482_K	0.924	0.96
34_I	79_P	0.917	0.96
71_W	78_E	0.914	0.96
293_L	296_Q	0.913	0.95
120_W	232_M	0.910	0.95
290_R	298_E	0.908	0.95
283_A	290_R	0.908	0.95
59_G	63_Q	0.908	0.95
163_A	245_T	0.907	0.95
240_A	248_Q	0.906	0.95
257_A	260_V	0.905	0.95
45_D	61_Y	0.904	0.95
39_Q	42_K	0.902	0.95
233_S	251_T	0.902	0.95
536_E	540_N	0.898	0.95
447_H	546_L	0.894	0.95
237_K	241_T	0.893	0.95
460_Q	466_A	0.889	0.95
121_V	260_V	0.888	0.95
32_E	35_S	0.887	0.95
357_W	380_V	0.885	0.95
353_R	357_W	0.884	0.95
510_S	513_L	0.883	0.95
366_L	378_D	0.882	0.95
152_E	207_M	0.881	0.95
174_N	227_D	0.881	0.95
358_D	384_G	0.877	0.94
479_L	483_Q	0.877	0.94
505_D	522_Q	0.875	0.94
483_Q	487_R	0.875	0.94
107_N	110_S	0.873	0.94
212_S	215_L	0.870	0.94
121_V	281_V	0.869	0.94
451_W	477_F	0.866	0.94
40_Q	56_V	0.861	0.94
72_Q	82_V	0.861	0.94
379_D	382_W	0.856	0.94
125_V	247_T	0.855	0.94
30_A	78_E	0.855	0.94
420_L	452_L	0.854	0.94
156_Q	214_T	0.853	0.94
485_F	512_L	0.853	0.94
254_V	260_V	0.850	0.93
187_G	191_Q	0.845	0.93
131_T	226_P	0.845	0.93
317_I	360_A	0.844	0.93
68_L	79_P	0.842	0.93
236_L	246_L	0.835	0.93
413_F	440_H	0.832	0.93
314_V	379_D	0.832	0.93
109_L	264_R	0.831	0.93
154_W	181_I	0.831	0.93
42_K	81_D	0.830	0.93
181_I	206_M	0.829	0.93
501_L	526_T	0.829	0.93
431_I	451_W	0.828	0.93
222_V	244_F	0.825	0.92
425_V	491_A	0.824	0.92
109_L	281_V	0.823	0.92
122_Q	282_R	0.820	0.92
448_I	546_L	0.819	0.92
506_E	520_W	0.815	0.92
100_V	280_V	0.813	0.92
264_R	303_W	0.812	0.92
94_P	141_K	0.810	0.92
438_A	463_P	0.806	0.91
35_S	38_Q	0.805	0.91
318_Q	330_V	0.805	0.91
263_V	266_E	0.804	0.91
172_L	242_A	0.802	0.91
70_Q	73_R	0.801	0.91
132_L	142_A	0.800	0.91
321_V	327_I	0.797	0.91
407_D	540_N	0.794	0.91
438_A	464_G	0.794	0.91
482_K	556_T	0.793	0.91
355_Q	400_L	0.793	0.91
81_D	167_T	0.793	0.91
202_V	218_L	0.793	0.91
520_W	526_T	0.790	0.91
119_L	281_V	0.788	0.91
539_E	544_K	0.787	0.90
91_V	153_D	0.787	0.90
181_I	218_L	0.786	0.90
542_Q	545_K	0.785	0.90
128_V	202_V	0.785	0.90
460_Q	470_S	0.785	0.90
36_R	67_R	0.785	0.90
384_G	389_K	0.785	0.90
29_R	32_E	0.785	0.90
309_A	378_D	0.781	0.90
29_R	75_F	0.779	0.90
363_D	384_G	0.779	0.90
287_P	299_W	0.774	0.90
469_K	472_Q	0.773	0.90
129_A	223_W	0.773	0.90
185_R	273_P	0.771	0.90
113_M	260_V	0.771	0.90
190_Q	217_S	0.770	0.90
175_S	239_L	0.769	0.89
540_N	543_I	0.767	0.89
94_P	131_T	0.765	0.89
511_Q	514_F	0.765	0.89
440_H	445_F	0.765	0.89
72_Q	83_M	0.762	0.89
252_R	263_V	0.762	0.89
465_I	470_S	0.760	0.89
338_L	373_G	0.759	0.89
444_R	462_T	0.756	0.89
408_V	542_Q	0.756	0.89
422_A	425_V	0.754	0.89
252_R	259_E	0.754	0.89
396_R	399_S	0.751	0.88
268_W	306_Q	0.749	0.88
206_M	214_T	0.749	0.88
72_Q	84_M	0.748	0.88
132_L	139_L	0.746	0.88
109_L	260_V	0.746	0.88
92_M	143_I	0.745	0.88
314_V	365_I	0.745	0.88
121_V	279_V	0.744	0.88
417_L	448_I	0.744	0.88
95_V	227_D	0.744	0.88
120_W	236_L	0.742	0.88
240_A	246_L	0.741	0.88
472_Q	475_H	0.739	0.88
386_E	389_K	0.738	0.87
232_M	287_P	0.737	0.87
113_M	116_R	0.736	0.87
33_E	71_W	0.731	0.87
438_A	465_I	0.731	0.87
445_F	451_W	0.730	0.87
460_Q	467_K	0.728	0.87
364_Q	381_V	0.727	0.87
34_I	75_F	0.727	0.87
419_W	425_V	0.724	0.86
347_N	373_G	0.722	0.86
460_Q	474_W	0.721	0.86
545_K	548_S	0.716	0.86
439_L	443_H	0.715	0.86
286_E	289_S	0.714	0.86
294_P	500_A	0.714	0.86
507_R	511_Q	0.712	0.86
339_D	372_Q	0.712	0.86
66_A	103_M	0.711	0.85
358_D	382_W	0.711	0.85
359_I	380_V	0.709	0.85
392_P	404_F	0.709	0.85
525_G	530_R	0.708	0.85
65_S	84_M	0.707	0.85
160_L	214_T	0.706	0.85
170_G	238_E	0.705	0.85
318_Q	345_R	0.705	0.85
80_R	138_K	0.704	0.85
310_Q	367_V	0.700	0.85
268_W	305_Y	0.700	0.85
116_R	290_R	0.699	0.84
139_L	142_A	0.699	0.84
433_E	437_R	0.697	0.84
505_D	523_L	0.696	0.84
514_F	544_K	0.694	0.84
80_R	85_P	0.694	0.84
338_L	341_K	0.692	0.84
168_V	171_P	0.692	0.84
513_L	516_T	0.689	0.84
384_G	388_T	0.689	0.84
549_W	552_A	0.688	0.84
191_Q	217_S	0.687	0.83
260_V	303_W	0.686	0.83
186_E	190_Q	0.685	0.83
191_Q	201_K	0.683	0.83
459_L	470_S	0.682	0.83
305_Y	372_Q	0.681	0.83
109_L	303_W	0.680	0.83
135_R	141_K	0.677	0.83
119_L	257_A	0.677	0.83
66_A	102_K	0.676	0.82
442_T	462_T	0.676	0.82
57_E	311_V	0.676	0.82
162_S	166_Q	0.676	0.82
169_S	172_L	0.675	0.82
175_S	242_A	0.674	0.82
210_D	216_N	0.674	0.82
488_W	491_A	0.672	0.82
501_L	525_G	0.670	0.82
319_F	351_V	0.670	0.82
109_L	113_M	0.669	0.82
102_K	301_V	0.669	0.82
46_D	169_S	0.666	0.82
129_A	224_A	0.666	0.82
497_T	534_V	0.666	0.82
120_W	251_T	0.665	0.81
30_A	74_C	0.664	0.81
435_G	473_L	0.662	0.81
191_Q	195_G	0.662	0.81
481_R	554_Q	0.661	0.81
222_V	246_L	0.661	0.81
38_Q	68_L	0.657	0.81
196_I	342_K	0.657	0.81
43_Q	56_V	0.656	0.81
263_V	279_V	0.656	0.81
392_P	395_N	0.656	0.81
408_V	413_F	0.654	0.80
483_Q	488_W	0.653	0.80
338_L	367_V	0.652	0.80
103_M	109_L	0.651	0.80
69_T	101_R	0.651	0.80
464_G	470_S	0.651	0.80
111_L	115_E	0.650	0.80
50_K	89_G	0.648	0.80
426_L	491_A	0.648	0.80
484_P	556_T	0.647	0.80
156_Q	211_D	0.644	0.79
264_R	279_V	0.644	0.79
236_L	251_T	0.644	0.79
31_Q	78_E	0.644	0.79
429_D	479_L	0.643	0.79
438_A	442_T	0.641	0.79
161_I	164_V	0.641	0.79
221_F	247_T	0.639	0.79
395_N	404_F	0.639	0.79
315_K	318_Q	0.639	0.79
512_L	538_K	0.638	0.79
186_E	189_I	0.636	0.78
162_S	215_L	0.634	0.78
355_Q	358_D	0.633	0.78
478_N	482_K	0.632	0.78
118_D	231_L	0.632	0.78
485_F	509_W	0.632	0.78
211_D	215_L	0.631	0.78
505_D	511_Q	0.630	0.78
488_W	555_I	0.630	0.78
264_R	268_W	0.630	0.78
67_R	70_Q	0.629	0.78
97_H	143_I	0.629	0.78
546_L	549_W	0.629	0.78
521_Q	535_I	0.629	0.78
416_R	537_W	0.628	0.78
326_K	400_L	0.627	0.78
395_N	411_E	0.626	0.77
434_A	437_R	0.626	0.77
68_L	83_M	0.626	0.77
225_W	239_L	0.624	0.77
68_L	71_W	0.624	0.77
361_P	388_T	0.622	0.77
136_D	174_N	0.621	0.77
41_I	68_L	0.620	0.77
448_I	491_A	0.620	0.77
541_A	544_K	0.620	0.77
183_L	217_S	0.618	0.76
488_W	509_W	0.618	0.76
472_Q	476_Q	0.617	0.76
331_A	377_I	0.617	0.76
132_L	244_F	0.616	0.76
360_A	389_K	0.614	0.76
475_H	478_N	0.613	0.76
235_R	239_L	0.612	0.76
326_K	403_Y	0.612	0.76
205_L	208_R	0.612	0.76
276_T	305_Y	0.611	0.76
97_H	129_A	0.611	0.76
258_D	261_A	0.611	0.76
68_L	84_M	0.610	0.76
112_W	525_G	0.609	0.75
414_I	436_W	0.609	0.75
43_Q	46_D	0.608	0.75
131_T	176_T	0.607	0.75
221_F	272_L	0.607	0.75
530_R	533_Q	0.605	0.75
232_M	235_R	0.605	0.75
460_Q	471_A	0.604	0.75
123_P	279_V	0.602	0.75
139_L	166_Q	0.602	0.75
30_A	33_E	0.601	0.74
50_K	163_A	0.601	0.74
315_K	332_S	0.600	0.74
395_N	406_S	0.600	0.74
364_Q	385_A	0.598	0.74
453_L	552_A	0.598	0.74
361_P	389_K	0.598	0.74
150_K	487_R	0.598	0.74
162_S	217_S	0.597	0.74
509_W	513_L	0.597	0.74
49_W	65_S	0.596	0.74
163_A	182_F	0.596	0.74
495_P	533_Q	0.595	0.74
261_A	264_R	0.595	0.74
320_A	332_S	0.594	0.74
454_L	474_W	0.593	0.74
483_Q	556_T	0.593	0.74
421_G	428_L	0.593	0.74
464_G	525_G	0.593	0.74
232_M	236_L	0.592	0.73
501_L	534_V	0.590	0.73
347_N	376_R	0.589	0.73
457_E	460_Q	0.588	0.73
170_G	242_A	0.587	0.73
547_G	551_A	0.584	0.72
424_Q	490_M	0.583	0.72
523_L	526_T	0.583	0.72
160_L	217_S	0.583	0.72
132_L	158_V	0.580	0.72
205_L	216_N	0.579	0.72
434_A	438_A	0.579	0.72
196_I	339_D	0.579	0.72
385_A	389_K	0.579	0.72
476_Q	479_L	0.578	0.72
488_W	551_A	0.578	0.72
110_S	114_R	0.578	0.72
268_W	276_T	0.576	0.71
420_L	555_I	0.575	0.71
360_A	386_E	0.575	0.71
86_P	163_A	0.574	0.71
275_V	308_V	0.574	0.71
41_I	65_S	0.572	0.71
511_Q	515_S	0.572	0.71
382_W	385_A	0.572	0.71
169_S	244_F	0.571	0.71
40_Q	67_R	0.571	0.71
221_F	246_L	0.570	0.71
169_S	241_T	0.569	0.70
413_F	416_R	0.568	0.70
542_Q	546_L	0.568	0.70
426_L	555_I	0.568	0.70
435_G	469_K	0.568	0.70
488_W	550_L	0.567	0.70
455_T	470_S	0.567	0.70
270_A	276_T	0.566	0.70
154_W	158_V	0.565	0.70
453_L	457_E	0.565	0.70
131_T	143_I	0.564	0.70
147_N	150_K	0.563	0.70
509_W	551_A	0.563	0.70
521_Q	526_T	0.562	0.70
33_E	64_L	0.562	0.70
455_T	478_N	0.562	0.70
133_V	143_I	0.562	0.70
104_V	207_M	0.562	0.70
420_L	448_I	0.561	0.69
91_V	143_I	0.561	0.69
57_E	63_Q	0.561	0.69
104_V	368_S	0.561	0.69
195_G	209_Q	0.560	0.69
61_Y	65_S	0.559	0.69
337_M	341_K	0.559	0.69
439_L	451_W	0.559	0.69
407_D	537_W	0.559	0.69
101_R	301_V	0.559	0.69
268_W	372_Q	0.557	0.69
506_E	512_L	0.557	0.69
418_V	436_W	0.556	0.69
42_K	86_P	0.556	0.69
413_F	417_L	0.556	0.69
86_P	160_L	0.556	0.69
386_E	390_P	0.555	0.69
343_V	367_V	0.555	0.69
418_V	437_R	0.555	0.69
353_R	359_I	0.555	0.69
427_G	483_Q	0.554	0.68
439_L	442_T	0.554	0.68
442_T	463_P	0.553	0.68
526_T	534_V	0.552	0.68
208_R	214_T	0.552	0.68
491_A	503_A	0.552	0.68
142_A	154_W	0.552	0.68
174_N	226_P	0.551	0.68
263_V	267_W	0.551	0.68
109_L	257_A	0.550	0.68
195_G	345_R	0.550	0.68
115_E	298_E	0.550	0.68
156_Q	159_S	0.550	0.68
182_F	245_T	0.549	0.68
462_T	465_I	0.549	0.68
448_I	550_L	0.549	0.68
164_V	245_T	0.548	0.68
113_M	256_N	0.547	0.67
347_N	353_R	0.547	0.67
357_W	360_A	0.547	0.67
382_W	386_E	0.546	0.67
529_G	532_R	0.546	0.67
102_K	108_A	0.545	0.67
54_S	203_A	0.544	0.67
320_A	328_S	0.544	0.67
319_F	402_C	0.544	0.67
45_D	49_W	0.544	0.67
38_Q	81_D	0.543	0.67
446_E	450_S	0.543	0.67
144_S	154_W	0.542	0.67
30_A	34_I	0.542	0.67
339_D	373_G	0.542	0.67
384_G	387_R	0.541	0.67
358_D	389_K	0.541	0.67
52_G	207_M	0.541	0.67
177_L	244_F	0.540	0.66
447_H	545_K	0.540	0.66
170_G	241_T	0.540	0.66
192_Q	209_Q	0.539	0.66
544_K	547_G	0.538	0.66
104_V	264_R	0.538	0.66
327_I	351_V	0.538	0.66
226_P	235_R	0.537	0.66
436_W	473_L	0.537	0.66
526_T	530_R	0.537	0.66
59_G	307_P	0.536	0.66
276_T	373_G	0.535	0.66
509_W	512_L	0.535	0.66
488_W	556_T	0.535	0.66
97_H	176_T	0.535	0.66
184_Q	201_K	0.535	0.66
213_D	216_N	0.535	0.66
449_F	553_Q	0.532	0.65
223_W	274_F	0.532	0.65
185_R	189_I	0.531	0.65
34_I	77_S	0.531	0.65
255_K	284_A	0.531	0.65
423_K	429_D	0.531	0.65
219_G	222_V	0.530	0.65
63_Q	310_Q	0.530	0.65
44_W	57_E	0.530	0.65
156_Q	206_M	0.530	0.65
181_I	202_V	0.529	0.65
543_I	546_L	0.529	0.65
267_W	276_T	0.528	0.65
398_N	401_T	0.528	0.65
500_A	525_G	0.527	0.65
497_T	501_L	0.527	0.65
420_L	491_A	0.525	0.64
208_R	370_A	0.525	0.64
71_W	74_C	0.525	0.64
351_V	400_L	0.525	0.64
252_R	262_R	0.522	0.64
288_E	292_W	0.522	0.64
516_T	534_V	0.522	0.64
282_R	299_W	0.522	0.64
279_V	305_Y	0.521	0.64
182_F	274_F	0.521	0.64
465_I	473_L	0.520	0.64
481_R	553_Q	0.520	0.64
484_P	488_W	0.519	0.63
104_V	306_Q	0.518	0.63
364_Q	384_G	0.515	0.63
320_A	345_R	0.513	0.63
490_M	499_A	0.513	0.63
458_Q	466_A	0.512	0.62
442_T	461_N	0.511	0.62
463_P	466_A	0.511	0.62
360_A	382_W	0.511	0.62
520_W	525_G	0.510	0.62
283_A	286_E	0.510	0.62
538_K	547_G	0.510	0.62
209_Q	346_V	0.510	0.62
121_V	267_W	0.509	0.62
404_F	409_C	0.509	0.62
352_R	355_Q	0.509	0.62
425_V	487_R	0.508	0.62
220_V	245_T	0.506	0.62
133_V	227_D	0.506	0.62
439_L	473_L	0.506	0.62
83_M	86_P	0.505	0.61
101_R	293_L	0.505	0.61
167_T	171_P	0.505	0.61
405_A	540_N	0.504	0.61
462_T	466_A	0.504	0.61
207_M	370_A	0.503	0.61
31_Q	75_F	0.503	0.61
50_K	215_L	0.503	0.61
68_L	72_Q	0.502	0.61
40_Q	47_D	0.501	0.61
225_W	228_G	0.501	0.61
175_S	228_G	0.500	0.61

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3sgiA	1	0.65	100	0.083	Contact Map
2owoA	1	0.9518	100	0.091	Contact Map
1dgsA	1	0.9482	100	0.099	Contact Map
4glxA	1	0.9429	100	0.141	Contact Map
3uq8A	1	0.5071	100	0.511	Contact Map
1zauA	1	0.5054	100	0.515	Contact Map
3jslA	2	0.4946	100	0.516	Contact Map
4lh6A	1	0.5179	100	0.519	Contact Map
1b04A	1	0.5036	100	0.525	Contact Map
4glwA	2	0.4518	100	0.533	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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