YIDC - ECOLI - GREMLIN Contacts

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YIDC - Membrane protein insertase YidC

UniProt:	P25714	Sequences: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11197
Length:	548 (508)
Sequences:	1987 (1436)
Seq/√Len:	63.7

ECOLI - YIDC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
407_E	410_A	6.795	1.00
351_V	360_I	5.241	1.00
410_A	414_A	5.044	1.00
391_Q	394_R	4.769	1.00
64_K	85_P	4.547	1.00
356_F	451_F	4.242	1.00
342_K	346_W	4.180	1.00
386_L	417_V	4.153	1.00
389_K	392_A	4.053	1.00
394_R	398_G	3.831	1.00
393_M	404_I	3.748	1.00
343_L	364_I	3.434	1.00
64_K	69_D	3.389	1.00
391_Q	395_E	3.379	1.00
472_G	503_T	3.355	1.00
347_I	360_I	3.297	1.00
162_T	179_N	3.164	1.00
72_I	151_M	3.108	1.00
82_A	309_V	3.067	1.00
369_M	432_I	2.998	1.00
356_F	452_A	2.940	1.00
403_R	407_E	2.823	1.00
347_I	364_I	2.782	1.00
70_L	82_A	2.743	1.00
65_T	167_L	2.695	1.00
403_R	406_Q	2.674	1.00
394_R	404_I	2.551	1.00
402_Q	406_Q	2.542	1.00
356_F	360_I	2.499	1.00
346_W	350_F	2.485	1.00
387_Q	391_Q	2.471	1.00
261_A	327_T	2.467	1.00
470_L	518_I	2.461	1.00
166_V	177_N	2.453	1.00
467_L	515_L	2.347	1.00
69_D	83_L	2.342	1.00
296_Q	299_Q	2.331	1.00
347_I	351_V	2.329	1.00
70_L	79_V	2.316	1.00
392_A	396_R	2.308	1.00
62_S	69_D	2.306	1.00
381_A	384_R	2.194	1.00
397_L	403_R	2.185	1.00
168_K	175_N	2.185	1.00
160_T	181_Q	2.165	1.00
404_I	408_M	2.154	1.00
67_V	86_A	2.152	1.00
177_N	304_N	2.150	1.00
70_L	167_L	2.149	1.00
7_L	11_A	2.116	1.00
77_G	151_M	2.109	1.00
356_F	359_I	2.076	1.00
63_V	167_L	2.067	1.00
474_T	521_N	2.044	1.00
173_A	320_V	2.037	1.00
71_T	81_Q	2.026	1.00
60_L	71_T	2.008	1.00
490_M	494_I	1.973	1.00
398_G	404_I	1.936	1.00
134_E	152_T	1.919	1.00
63_V	72_I	1.919	1.00
234_K	237_T	1.884	1.00
152_T	162_T	1.865	1.00
179_N	302_A	1.855	1.00
60_L	80_E	1.846	1.00
164_T	179_N	1.820	1.00
448_Q	460_A	1.817	1.00
340_L	365_V	1.817	1.00
162_T	181_Q	1.802	1.00
62_S	71_T	1.795	1.00
308_W	316_K	1.794	1.00
150_P	164_T	1.784	1.00
530_L	534_G	1.783	1.00
196_L	307_L	1.781	1.00
61_I	74_T	1.778	1.00
485_T	492_Q	1.774	1.00
69_D	85_P	1.764	1.00
369_M	428_I	1.749	1.00
83_L	98_Q	1.744	0.99
24_E	27_K	1.743	0.99
406_Q	410_A	1.739	0.99
360_I	364_I	1.728	0.99
400_D	403_R	1.706	0.99
497_F	500_V	1.700	0.99
364_I	368_I	1.692	0.99
363_F	523_V	1.687	0.99
58_G	73_N	1.684	0.99
480_K	496_T	1.674	0.99
371_P	375_A	1.673	0.99
470_L	474_T	1.672	0.99
359_I	519_V	1.652	0.99
148_Q	164_T	1.651	0.99
360_I	363_F	1.643	0.99
526_I	530_L	1.634	0.99
389_K	415_E	1.630	0.99
173_A	306_T	1.626	0.99
393_M	408_M	1.622	0.99
390_I	393_M	1.617	0.99
344_L	357_S	1.611	0.99
398_G	401_K	1.607	0.99
66_D	170_G	1.604	0.99
501_I	505_F	1.578	0.99
351_V	356_F	1.577	0.99
177_N	302_A	1.572	0.99
275_Y	287_G	1.567	0.99
254_A	327_T	1.563	0.99
9_V	13_L	1.562	0.99
469_I	500_V	1.549	0.99
64_K	139_V	1.548	0.99
497_F	501_I	1.546	0.99
24_E	28_N	1.532	0.99
148_Q	166_V	1.512	0.99
250_G	269_D	1.505	0.98
68_L	82_A	1.495	0.98
30_Q	33_A	1.488	0.98
522_L	526_I	1.483	0.98
493_K	497_F	1.458	0.98
31_P	34_Q	1.458	0.98
375_A	378_T	1.458	0.98
181_Q	300_T	1.452	0.98
490_M	493_K	1.439	0.98
473_V	477_F	1.433	0.98
469_I	473_V	1.427	0.98
401_K	404_I	1.422	0.98
164_T	177_N	1.417	0.98
20_W	24_E	1.410	0.98
166_V	175_N	1.410	0.98
160_T	183_A	1.409	0.98
7_L	14_F	1.406	0.98
343_L	368_I	1.403	0.98
359_I	515_L	1.402	0.98
17_F	21_Q	1.383	0.97
315_D	345_K	1.370	0.97
407_E	414_A	1.364	0.97
87_Y	313_I	1.357	0.97
81_Q	98_Q	1.356	0.97
19_I	22_A	1.355	0.97
365_V	436_L	1.353	0.97
432_I	523_V	1.351	0.97
366_R	369_M	1.333	0.97
401_K	405_S	1.332	0.97
382_K	385_M	1.320	0.96
500_V	503_T	1.317	0.96
113_G	193_F	1.315	0.96
32_Q	35_Q	1.313	0.96
365_V	428_I	1.310	0.96
476_F	496_T	1.309	0.96
67_V	171_D	1.305	0.96
148_Q	177_N	1.304	0.96
478_I	525_I	1.300	0.96
163_K	178_Y	1.298	0.96
73_N	80_E	1.294	0.96
372_L	510_P	1.291	0.96
392_A	401_K	1.285	0.96
351_V	357_S	1.271	0.96
108_Y	262_T	1.267	0.96
141_A	146_E	1.267	0.96
68_L	167_L	1.265	0.96
154_T	160_T	1.262	0.95
434_L	438_Y	1.246	0.95
100_L	262_T	1.244	0.95
35_Q	38_Q	1.244	0.95
495_M	506_F	1.244	0.95
393_M	397_L	1.243	0.95
165_F	176_V	1.241	0.95
175_N	304_N	1.236	0.95
395_E	398_G	1.235	0.95
87_Y	444_V	1.230	0.95
9_V	12_L	1.224	0.95
313_I	316_K	1.224	0.95
529_Q	533_R	1.223	0.95
476_F	480_K	1.220	0.95
316_K	319_A	1.219	0.95
471_M	503_T	1.217	0.94
455_I	467_L	1.216	0.94
67_V	172_Y	1.212	0.94
86_A	172_Y	1.207	0.94
37_T	40_T	1.203	0.94
168_K	171_D	1.201	0.94
214_A	217_T	1.198	0.94
11_A	15_V	1.187	0.94
129_P	153_Y	1.175	0.93
79_V	165_F	1.171	0.93
9_V	16_S	1.170	0.93
493_K	496_T	1.166	0.93
426_L	430_M	1.162	0.93
189_E	294_L	1.156	0.93
216_H	219_R	1.151	0.93
347_I	357_S	1.147	0.93
503_T	507_L	1.145	0.92
116_G	120_P	1.137	0.92
492_Q	496_T	1.137	0.92
23_W	27_K	1.135	0.92
346_W	349_S	1.133	0.92
58_G	75_R	1.127	0.92
392_A	395_E	1.124	0.92
393_M	411_L	1.118	0.92
30_Q	34_Q	1.118	0.92
335_F	339_P	1.117	0.91
376_Q	380_M	1.117	0.91
373_T	376_Q	1.116	0.91
509_F	517_Y	1.116	0.91
460_A	511_S	1.113	0.91
179_N	300_T	1.100	0.91
438_Y	442_G	1.098	0.91
150_P	162_T	1.093	0.91
89_K	95_Q	1.090	0.90
330_Y	341_F	1.081	0.90
134_E	162_T	1.073	0.90
348_H	352_G	1.069	0.90
68_L	79_V	1.064	0.89
471_M	478_I	1.063	0.89
236_D	240_D	1.056	0.89
393_M	398_G	1.044	0.88
461_Q	507_L	1.043	0.88
213_F	216_H	1.042	0.88
323_H	326_L	1.039	0.88
72_I	149_V	1.038	0.88
110_A	307_L	1.035	0.88
72_I	165_F	1.032	0.88
336_I	340_L	1.030	0.88
286_I	290_S	1.027	0.88
75_R	130_L	1.024	0.87
457_D	499_P	1.022	0.87
19_I	23_W	1.020	0.87
340_L	361_I	1.019	0.87
14_F	18_M	1.015	0.87
410_A	413_K	1.015	0.87
376_Q	520_S	1.012	0.87
61_I	133_V	1.007	0.87
386_L	393_M	1.006	0.87
196_L	262_T	1.005	0.86
408_M	412_Y	1.002	0.86
432_I	436_L	0.998	0.86
345_K	349_S	0.987	0.85
58_G	74_T	0.987	0.85
25_Q	28_N	0.985	0.85
72_I	167_L	0.983	0.85
472_G	475_M	0.982	0.85
167_L	174_V	0.981	0.85
133_V	152_T	0.980	0.85
239_A	284_A	0.976	0.85
77_G	163_K	0.975	0.85
91_L	456_H	0.974	0.85
390_I	408_M	0.974	0.85
482_S	485_T	0.970	0.84
500_V	504_V	0.969	0.84
7_L	435_A	0.967	0.84
187_P	296_Q	0.962	0.84
29_P	32_Q	0.957	0.84
515_L	519_V	0.953	0.83
263_A	327_T	0.953	0.83
340_L	428_I	0.952	0.83
152_T	160_T	0.947	0.83
260_F	311_P	0.945	0.83
359_I	452_A	0.944	0.83
518_I	522_L	0.940	0.83
366_R	520_S	0.938	0.82
435_A	439_M	0.938	0.82
221_A	224_S	0.937	0.82
430_M	433_F	0.936	0.82
60_L	74_T	0.933	0.82
294_L	297_P	0.930	0.82
359_I	474_T	0.927	0.82
89_K	97_F	0.926	0.82
36_T	39_T	0.924	0.81
81_Q	101_E	0.924	0.81
488_D	491_Q	0.924	0.81
377_Y	381_A	0.923	0.81
175_N	306_T	0.919	0.81
172_Y	311_P	0.917	0.81
133_V	136_D	0.917	0.81
68_L	174_V	0.902	0.80
347_I	350_F	0.902	0.80
502_F	505_F	0.902	0.80
28_N	32_Q	0.899	0.80
520_S	524_T	0.893	0.79
424_F	427_L	0.892	0.79
456_H	461_Q	0.879	0.78
454_W	515_L	0.878	0.78
354_W	446_L	0.878	0.78
221_A	238_I	0.877	0.78
499_P	528_Q	0.877	0.78
110_A	196_L	0.876	0.78
376_Q	532_Y	0.872	0.78
433_F	436_L	0.872	0.78
150_P	179_N	0.871	0.78
185_E	297_P	0.869	0.77
88_P	448_Q	0.868	0.77
369_M	523_V	0.868	0.77
13_L	16_S	0.866	0.77
220_G	224_S	0.865	0.77
212_N	215_L	0.863	0.77
111_Q	195_Q	0.860	0.77
12_L	16_S	0.860	0.77
56_G	130_L	0.859	0.77
348_H	357_S	0.856	0.76
261_A	317_M	0.854	0.76
453_L	456_H	0.853	0.76
263_A	324_L	0.853	0.76
374_K	432_I	0.853	0.76
67_V	170_G	0.852	0.76
394_R	481_M	0.849	0.76
357_S	451_F	0.849	0.76
87_Y	448_Q	0.849	0.76
369_M	520_S	0.841	0.75
312_E	442_G	0.840	0.75
21_Q	25_Q	0.840	0.75
63_V	149_V	0.839	0.75
426_L	517_Y	0.834	0.74
33_A	37_T	0.833	0.74
526_I	529_Q	0.833	0.74
504_V	508_W	0.833	0.74
220_G	223_Y	0.832	0.74
72_I	79_V	0.831	0.74
434_L	439_M	0.828	0.74
430_M	434_L	0.826	0.74
374_K	378_T	0.825	0.74
430_M	478_I	0.825	0.74
470_L	522_L	0.824	0.73
65_T	68_L	0.824	0.73
98_Q	101_E	0.819	0.73
376_Q	478_I	0.818	0.73
29_P	33_A	0.815	0.73
187_P	297_P	0.815	0.73
251_G	415_E	0.806	0.72
74_T	151_M	0.804	0.72
386_L	479_Q	0.803	0.72
142_E	146_E	0.803	0.72
90_E	95_Q	0.801	0.71
343_L	346_W	0.800	0.71
413_K	528_Q	0.795	0.71
343_L	361_I	0.793	0.71
382_K	469_I	0.791	0.70
39_T	42_T	0.789	0.70
348_H	354_W	0.789	0.70
14_F	20_W	0.785	0.70
329_D	438_Y	0.785	0.70
184_G	298_G	0.785	0.70
314_Q	330_Y	0.785	0.70
474_T	525_I	0.779	0.69
6_N	9_V	0.778	0.69
437_Y	509_F	0.778	0.69
386_L	398_G	0.773	0.69
393_M	428_I	0.772	0.69
396_R	407_E	0.772	0.69
362_T	371_P	0.772	0.69
380_M	471_M	0.771	0.68
332_W	476_F	0.769	0.68
23_W	28_N	0.768	0.68
217_T	220_G	0.768	0.68
481_M	485_T	0.767	0.68
8_L	12_L	0.766	0.68
34_Q	38_Q	0.766	0.68
171_D	316_K	0.765	0.68
472_G	479_Q	0.764	0.68
146_E	168_K	0.757	0.67
224_S	334_W	0.757	0.67
7_L	10_I	0.756	0.67
250_G	267_H	0.755	0.67
172_Y	252_W	0.753	0.67
350_F	360_I	0.753	0.67
370_Y	482_S	0.749	0.66
252_W	447_R	0.749	0.66
13_L	17_F	0.749	0.66
327_T	330_Y	0.748	0.66
467_L	518_I	0.746	0.66
478_I	520_S	0.746	0.66
523_V	528_Q	0.745	0.66
11_A	14_F	0.744	0.66
82_A	97_F	0.743	0.66
172_Y	447_R	0.742	0.65
377_Y	532_Y	0.741	0.65
417_V	524_T	0.740	0.65
362_T	480_K	0.738	0.65
159_N	188_L	0.738	0.65
373_T	524_T	0.737	0.65
10_I	13_L	0.737	0.65
88_P	94_T	0.736	0.65
220_G	232_K	0.735	0.65
437_Y	441_M	0.735	0.65
353_N	454_W	0.735	0.65
153_Y	161_F	0.734	0.65
6_N	13_L	0.734	0.65
366_R	524_T	0.734	0.65
239_A	278_N	0.733	0.65
368_I	371_P	0.733	0.65
484_T	487_T	0.731	0.64
5_R	8_L	0.730	0.64
155_D	161_F	0.730	0.64
34_Q	39_T	0.728	0.64
59_K	136_D	0.727	0.64
316_K	320_V	0.725	0.64
32_Q	36_T	0.722	0.63
61_I	165_F	0.721	0.63
370_Y	530_L	0.720	0.63
365_V	505_F	0.719	0.63
40_T	245_N	0.719	0.63
380_M	527_Q	0.718	0.63
13_L	473_V	0.718	0.63
372_L	376_Q	0.717	0.63
469_I	501_I	0.716	0.63
225_T	248_S	0.715	0.63
359_I	451_F	0.714	0.62
71_T	80_E	0.713	0.62
479_Q	482_S	0.710	0.62
461_Q	464_Y	0.709	0.62
77_G	396_R	0.708	0.62
376_Q	529_Q	0.708	0.62
390_I	411_L	0.708	0.62
498_M	501_I	0.707	0.62
517_Y	521_N	0.707	0.62
265_I	306_T	0.706	0.62
389_K	414_A	0.706	0.62
439_M	517_Y	0.706	0.62
293_V	301_G	0.704	0.61
452_A	456_H	0.703	0.61
12_L	15_V	0.701	0.61
59_K	74_T	0.700	0.61
380_M	483_P	0.700	0.61
341_F	443_S	0.699	0.61
135_K	149_V	0.698	0.61
411_L	414_A	0.696	0.61
471_M	525_I	0.696	0.61
173_A	265_I	0.696	0.61
221_A	255_M	0.694	0.60
93_S	96_P	0.693	0.60
393_M	400_D	0.691	0.60
376_Q	405_S	0.690	0.60
487_T	492_Q	0.689	0.60
393_M	407_E	0.689	0.60
417_V	479_Q	0.688	0.60
270_G	273_N	0.688	0.60
291_Q	474_T	0.687	0.60
82_A	167_L	0.687	0.60
10_I	21_Q	0.686	0.59
340_L	439_M	0.684	0.59
377_Y	384_R	0.683	0.59
66_D	142_E	0.683	0.59
381_A	532_Y	0.682	0.59
370_Y	374_K	0.682	0.59
376_Q	471_M	0.682	0.59
482_S	487_T	0.680	0.59
54_A	185_E	0.678	0.58
412_Y	418_N	0.677	0.58
83_L	96_P	0.677	0.58
364_I	519_V	0.676	0.58
403_R	413_K	0.676	0.58
35_Q	39_T	0.675	0.58
30_Q	40_T	0.675	0.58
477_F	522_L	0.675	0.58
471_M	524_T	0.675	0.58
478_I	482_S	0.674	0.58
525_I	529_Q	0.674	0.58
376_Q	482_S	0.674	0.58
89_K	93_S	0.673	0.58
218_F	221_A	0.673	0.58
236_D	239_A	0.671	0.58
366_R	523_V	0.670	0.58
324_L	434_L	0.669	0.57
34_Q	37_T	0.669	0.57
33_A	36_T	0.669	0.57
465_Y	507_L	0.668	0.57
489_P	493_K	0.668	0.57
141_A	147_L	0.667	0.57
341_F	439_M	0.665	0.57
273_N	428_I	0.664	0.57
348_H	351_V	0.662	0.57
101_E	106_F	0.661	0.57
35_Q	42_T	0.659	0.56
392_A	511_S	0.659	0.56
75_R	128_R	0.659	0.56
373_T	417_V	0.658	0.56
365_V	408_M	0.657	0.56
217_T	441_M	0.656	0.56
391_Q	398_G	0.656	0.56
224_S	323_H	0.656	0.56
490_M	495_M	0.655	0.56
488_D	493_K	0.655	0.56
36_T	41_T	0.654	0.56
383_M	393_M	0.654	0.56
180_V	303_M	0.653	0.56
440_L	503_T	0.653	0.56
101_E	336_I	0.652	0.56
29_P	34_Q	0.650	0.55
483_P	495_M	0.648	0.55
465_Y	506_F	0.647	0.55
261_A	308_W	0.647	0.55
370_Y	534_G	0.647	0.55
4_Q	333_L	0.647	0.55
317_M	320_V	0.647	0.55
482_S	528_Q	0.646	0.55
260_F	447_R	0.644	0.55
15_V	19_I	0.643	0.55
344_L	440_L	0.643	0.55
139_V	390_I	0.642	0.54
365_V	373_T	0.641	0.54
373_T	377_Y	0.640	0.54
125_N	129_P	0.640	0.54
31_P	35_Q	0.639	0.54
308_W	317_M	0.637	0.54
461_Q	465_Y	0.636	0.54
255_M	290_S	0.634	0.53
198_Q	255_M	0.634	0.53
55_S	75_R	0.634	0.53
357_S	435_A	0.633	0.53
339_P	509_F	0.633	0.53
385_M	451_F	0.632	0.53
32_Q	37_T	0.632	0.53
293_V	296_Q	0.631	0.53
38_Q	136_D	0.630	0.53
392_A	494_I	0.630	0.53
259_Y	439_M	0.630	0.53
224_S	386_L	0.629	0.53
340_L	368_I	0.629	0.53
177_N	268_N	0.626	0.53
366_R	440_L	0.625	0.52
295_V	301_G	0.623	0.52
347_I	396_R	0.622	0.52
255_M	453_L	0.621	0.52
479_Q	503_T	0.620	0.52
213_F	217_T	0.620	0.52
282_G	286_I	0.618	0.52
477_F	480_K	0.617	0.52
495_M	500_V	0.617	0.52
261_A	496_T	0.616	0.51
254_A	438_Y	0.616	0.51
86_A	89_K	0.615	0.51
38_Q	41_T	0.615	0.51
163_K	176_V	0.614	0.51
224_S	229_K	0.614	0.51
219_R	230_Y	0.613	0.51
412_Y	419_P	0.613	0.51
150_P	153_Y	0.613	0.51
264_W	305_S	0.611	0.51
469_I	503_T	0.610	0.51
134_E	150_P	0.610	0.51
62_S	139_V	0.610	0.51
33_A	368_I	0.610	0.51
336_I	523_V	0.610	0.51
324_L	482_S	0.610	0.51
66_D	147_L	0.609	0.51
185_E	298_G	0.609	0.51
361_I	365_V	0.609	0.51
209_G	212_N	0.608	0.50
402_Q	474_T	0.608	0.50
314_Q	328_V	0.608	0.50
378_T	382_K	0.607	0.50
112_S	307_L	0.607	0.50
62_S	501_I	0.606	0.50
63_V	466_I	0.603	0.50
40_T	54_A	0.602	0.50
488_D	495_M	0.602	0.50
161_F	285_A	0.602	0.50
34_Q	40_T	0.602	0.50
258_Q	438_Y	0.600	0.50
27_K	30_Q	0.600	0.50
252_W	265_I	0.600	0.50
9_V	24_E	0.598	0.49
253_V	276_T	0.597	0.49
154_T	159_N	0.597	0.49
125_N	153_Y	0.597	0.49
521_N	524_T	0.596	0.49
314_Q	317_M	0.596	0.49
258_Q	442_G	0.595	0.49
435_A	507_L	0.595	0.49
267_H	306_T	0.595	0.49
376_Q	432_I	0.595	0.49
258_Q	443_S	0.594	0.49
363_F	366_R	0.594	0.49
184_G	297_P	0.592	0.49
11_A	37_T	0.592	0.49
409_M	412_Y	0.592	0.49
4_Q	7_L	0.592	0.49
385_M	435_A	0.592	0.49
6_N	10_I	0.591	0.49
340_L	357_S	0.591	0.49
383_M	426_L	0.590	0.48
367_G	390_I	0.589	0.48
389_K	455_I	0.589	0.48
423_C	483_P	0.588	0.48
237_T	268_N	0.587	0.48
68_L	85_P	0.587	0.48
348_H	356_F	0.587	0.48
132_N	186_K	0.586	0.48
61_I	64_K	0.586	0.48
509_F	527_Q	0.586	0.48
402_Q	405_S	0.585	0.48
116_G	119_G	0.585	0.48
14_F	17_F	0.585	0.48
472_G	506_F	0.584	0.48
318_A	322_P	0.584	0.48
5_R	9_V	0.584	0.48
254_A	421_G	0.582	0.47
405_S	496_T	0.582	0.47
365_V	433_F	0.581	0.47
477_F	481_M	0.580	0.47
275_Y	289_K	0.579	0.47
371_P	374_K	0.578	0.47
509_F	514_V	0.577	0.47
10_I	14_F	0.577	0.47
55_S	61_I	0.577	0.47
18_M	228_E	0.577	0.47
29_P	357_S	0.576	0.47
361_I	497_F	0.575	0.47
22_A	26_D	0.575	0.47
334_W	524_T	0.575	0.47
31_P	62_S	0.574	0.47
451_F	472_G	0.574	0.47
114_L	161_F	0.573	0.46
468_P	515_L	0.573	0.46
524_T	533_R	0.572	0.46
77_G	196_L	0.571	0.46
344_L	374_K	0.571	0.46
191_S	289_K	0.571	0.46
76_G	113_G	0.570	0.46
479_Q	498_M	0.569	0.46
471_M	528_Q	0.567	0.46
358_I	516_Y	0.566	0.46
61_I	151_M	0.565	0.46
191_S	292_P	0.565	0.46
133_V	149_V	0.564	0.45
432_I	514_V	0.564	0.45
388_P	423_C	0.564	0.45
428_I	450_P	0.564	0.45
366_R	532_Y	0.564	0.45
215_L	218_F	0.564	0.45
468_P	514_V	0.563	0.45
465_Y	468_P	0.563	0.45
477_F	525_I	0.563	0.45
311_P	447_R	0.563	0.45
224_S	451_F	0.562	0.45
383_M	489_P	0.561	0.45
308_W	320_V	0.561	0.45
308_W	473_V	0.561	0.45
495_M	503_T	0.560	0.45
463_P	468_P	0.559	0.45
2_D	487_T	0.558	0.45
141_A	148_Q	0.557	0.45
369_M	376_Q	0.557	0.45
87_Y	390_I	0.556	0.44
353_N	455_I	0.556	0.44
474_T	477_F	0.555	0.44
26_D	29_P	0.554	0.44
223_Y	244_L	0.554	0.44
387_Q	511_S	0.554	0.44
182_N	366_R	0.553	0.44
518_I	524_T	0.552	0.44
350_F	393_M	0.552	0.44
254_A	263_A	0.551	0.44
371_P	428_I	0.551	0.44
433_F	521_N	0.551	0.44
433_F	472_G	0.550	0.44
435_A	484_T	0.550	0.44
371_P	378_T	0.549	0.44
154_T	157_A	0.548	0.44
475_M	479_Q	0.548	0.44
447_R	517_Y	0.547	0.43
418_N	483_P	0.546	0.43
32_Q	38_Q	0.545	0.43
259_Y	459_S	0.545	0.43
238_I	278_N	0.545	0.43
495_M	509_F	0.545	0.43
440_L	463_P	0.545	0.43
380_M	482_S	0.543	0.43
178_Y	305_S	0.542	0.43
475_M	478_I	0.542	0.43
29_P	35_Q	0.541	0.43
211_S	216_H	0.541	0.43
27_K	366_R	0.541	0.43
394_R	401_K	0.539	0.43
79_V	82_A	0.539	0.43
61_I	149_V	0.539	0.43
337_S	441_M	0.539	0.43
250_G	272_N	0.538	0.42
224_S	228_E	0.538	0.42
132_N	152_T	0.537	0.42
178_Y	340_L	0.536	0.42
63_V	174_V	0.536	0.42
483_P	493_K	0.536	0.42
126_G	131_Y	0.535	0.42
4_Q	376_Q	0.535	0.42
463_P	483_P	0.535	0.42
369_M	514_V	0.534	0.42
376_Q	421_G	0.533	0.42
271_T	278_N	0.532	0.42
35_Q	41_T	0.532	0.42
162_T	177_N	0.532	0.42
499_P	521_N	0.532	0.42
377_Y	447_R	0.532	0.42
151_M	362_T	0.530	0.42
35_Q	40_T	0.530	0.42
210_S	215_L	0.530	0.42
520_S	529_Q	0.530	0.42
263_A	434_L	0.530	0.42
212_N	216_H	0.529	0.41
176_V	264_W	0.528	0.41
430_M	441_M	0.527	0.41
346_W	360_I	0.527	0.41
261_A	340_L	0.527	0.41
312_E	517_Y	0.526	0.41
506_F	518_I	0.526	0.41
177_N	300_T	0.526	0.41
56_G	186_K	0.525	0.41
455_I	514_V	0.525	0.41
318_A	325_D	0.525	0.41
126_G	456_H	0.524	0.41
369_M	378_T	0.524	0.41
358_I	525_I	0.524	0.41
36_T	42_T	0.524	0.41
377_Y	398_G	0.523	0.41
34_Q	41_T	0.520	0.40
84_L	447_R	0.519	0.40
370_Y	378_T	0.519	0.40
475_M	483_P	0.519	0.40
341_F	356_F	0.519	0.40
291_Q	296_Q	0.519	0.40
324_L	524_T	0.518	0.40
182_N	297_P	0.518	0.40
308_W	313_I	0.518	0.40
334_W	405_S	0.518	0.40
265_I	324_L	0.516	0.40
198_Q	219_R	0.516	0.40
55_S	149_V	0.516	0.40
74_T	130_L	0.516	0.40
482_S	523_V	0.516	0.40
359_I	472_G	0.516	0.40
24_E	29_P	0.515	0.40
380_M	419_P	0.515	0.40
60_L	81_Q	0.515	0.40
354_W	365_V	0.515	0.40
28_N	34_Q	0.514	0.40
412_Y	506_F	0.512	0.40
498_M	502_F	0.512	0.40
494_I	509_F	0.511	0.39
530_L	533_R	0.511	0.39
362_T	520_S	0.510	0.39
421_G	478_I	0.510	0.39
163_K	340_L	0.510	0.39
288_Y	291_Q	0.509	0.39
386_L	412_Y	0.509	0.39
244_L	469_I	0.508	0.39
30_Q	69_D	0.507	0.39
367_G	522_L	0.507	0.39
16_S	24_E	0.506	0.39
142_E	145_N	0.506	0.39
101_E	264_W	0.506	0.39
198_Q	257_Q	0.505	0.39
381_A	415_E	0.505	0.39
480_K	484_T	0.504	0.39
532_Y	535_L	0.504	0.39
59_K	280_G	0.503	0.39
365_V	441_M	0.503	0.39
211_S	215_L	0.503	0.39
521_N	531_I	0.503	0.39
103_S	139_V	0.502	0.38
437_Y	495_M	0.501	0.38
110_A	264_W	0.501	0.38
20_W	405_S	0.501	0.38
92_N	203_P	0.501	0.38
250_G	268_N	0.501	0.38
91_L	494_I	0.500	0.38

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3wvfA	1	0.8212	100	0.215	Contact Map
3wo6A	1	0.3668	100	0.61	Contact Map
3blcA	4	0.5091	100	0.691	Contact Map
3bs6A	3	0.4745	100	0.756	Contact Map
3q1nA	1	0.427	83.2	0.972	Contact Map
1jovA	1	0.427	45.4	0.978	Contact Map
2cirA	1	0.427	44.2	0.978	Contact Map
3dcdA	1	0.4398	40.7	0.979	Contact Map
1ygaA	2	0.4544	39.3	0.979	Contact Map
1yewA	3	0.323	36.3	0.98	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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