GABP - ECOLI - GREMLIN Contacts

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GABP - GABA permease

UniProt:	P25527	Sequences: MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFWVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKVIAILAFIFLGAVAISGFYPYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSVLELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTPYVAVLLSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAEGSEIRLRMWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMARWKKLVLWQKTPVHNTR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11330
Length:	466 (422)
Sequences:	24885 (16073)
Seq/√Len:	782.4

ECOLI - GABP LYSP MMUP AROP PROY PHEP ANSP CYCA YIFK PLAP FRLA PUUP GADC YCAM POTE YJEM YGJI ADIC YBAT ARCD YJEH CADB TNAB MTR
BACSU - YBGF ROCC GABP HUTM YTNA YBXG ROCE YDGF AAPA YVBW ASPP YHDG STET YBEC YCGH YFNA ARCD YECA YDAO GERBB YNDE GERAB GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97X49 Q97WS3 Q97Z63 Q97U05 Q97ZB5 Q97XM0 Q7LXI7 Q97VA6 Q97U33 Q97WD4 Q97VA8 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
138_T	342_T	4.305	1.00
324_V	336_V	4.267	1.00
384_R	388_I	3.406	1.00
55_G	246_S	3.190	1.00
376_L	411_I	3.175	1.00
327_K	336_V	3.065	1.00
232_K	236_R	3.002	1.00
15_K	228_D	2.857	1.00
227_S	233_H	2.679	1.00
79_S	318_R	2.646	1.00
95_G	315_L	2.617	1.00
229_T	232_K	2.583	1.00
316_S	326_G	2.549	1.00
170_G	255_V	2.538	1.00
329_N	335_Y	2.526	1.00
131_L	346_F	2.492	1.00
20_T	240_S	2.446	1.00
324_V	327_K	2.428	1.00
16_S	240_S	2.405	1.00
168_F	172_V	2.279	1.00
225_A	317_R	2.265	1.00
284_H	288_I	2.237	1.00
379_A	410_V	2.232	1.00
442_I	446_P	2.203	1.00
226_E	310_R	2.167	1.00
67_E	386_R	2.166	1.00
83_D	91_G	2.156	1.00
139_G	143_L	2.148	1.00
339_L	343_G	2.134	1.00
16_S	233_H	2.118	1.00
19_V	227_S	2.108	1.00
313_Y	317_R	2.107	1.00
275_S	278_E	2.092	1.00
16_S	20_T	2.067	1.00
135_L	346_F	2.058	1.00
146_K	150_E	2.049	1.00
138_T	338_V	2.034	1.00
142_L	335_Y	2.011	1.00
236_R	240_S	2.009	1.00
122_P	125_P	1.957	1.00
86_I	384_R	1.950	1.00
408_W	412_G	1.907	1.00
319_G	323_A	1.904	1.00
15_K	18_H	1.900	1.00
130_S	349_V	1.900	1.00
83_D	88_R	1.899	1.00
64_M	379_A	1.899	1.00
437_L	441_I	1.893	1.00
436_L	440_G	1.885	1.00
325_M	340_L	1.883	1.00
99_W	341_S	1.880	1.00
131_L	349_V	1.865	1.00
157_L	161_I	1.864	1.00
39_A	47_V	1.857	1.00
56_L	60_M	1.844	1.00
10_L	328_I	1.843	1.00
86_I	380_V	1.834	1.00
441_I	445_V	1.785	1.00
261_P	264_M	1.757	1.00
405_W	409_L	1.751	1.00
275_S	279_L	1.749	1.00
440_G	443_C	1.743	1.00
229_T	233_H	1.733	1.00
57_L	413_F	1.729	1.00
329_N	333_T	1.724	1.00
239_N	243_W	1.714	1.00
18_H	153_F	1.707	1.00
380_V	411_I	1.705	1.00
264_M	279_L	1.704	1.00
134_T	345_A	1.671	1.00
82_A	94_I	1.669	1.00
438_A	442_I	1.669	1.00
444_T	448_M	1.665	1.00
135_L	342_T	1.658	1.00
142_L	339_L	1.637	1.00
106_I	345_A	1.628	1.00
20_T	244_R	1.623	1.00
141_N	302_N	1.618	1.00
23_S	241_V	1.608	1.00
331_S	335_Y	1.604	1.00
384_R	387_K	1.598	1.00
412_G	416_F	1.595	1.00
433_S	436_L	1.594	1.00
161_I	165_A	1.593	1.00
94_I	377_V	1.592	1.00
110_A	301_L	1.592	1.00
50_A	206_A	1.583	1.00
434_T	438_A	1.556	1.00
87_G	90_A	1.555	1.00
14_L	18_H	1.542	1.00
60_M	409_L	1.531	1.00
117_L	129_F	1.530	1.00
243_W	247_I	1.506	1.00
440_G	444_T	1.471	1.00
445_V	449_A	1.467	1.00
269_A	275_S	1.467	1.00
223_A	306_Y	1.458	1.00
312_L	337_A	1.454	1.00
54_A	210_T	1.443	1.00
134_T	342_T	1.440	1.00
56_L	409_L	1.439	1.00
278_E	286_K	1.439	1.00
336_V	340_L	1.421	1.00
308_A	341_S	1.420	1.00
143_L	331_S	1.417	1.00
46_A	196_M	1.409	1.00
313_Y	328_I	1.400	1.00
229_T	236_R	1.393	1.00
323_A	326_G	1.386	1.00
162_A	292_V	1.378	1.00
438_A	441_I	1.374	1.00
171_A	255_V	1.374	1.00
62_M	242_I	1.372	1.00
82_A	377_V	1.372	1.00
131_L	135_L	1.371	1.00
309_S	338_V	1.362	1.00
10_L	313_Y	1.361	1.00
433_S	440_G	1.359	1.00
383_L	408_W	1.359	1.00
110_A	134_T	1.355	1.00
380_V	384_R	1.352	1.00
75_T	225_A	1.343	1.00
327_K	335_Y	1.333	1.00
11_G	332_K	1.331	1.00
323_A	327_K	1.329	1.00
138_T	339_L	1.329	1.00
160_V	164_L	1.320	1.00
72_T	84_K	1.317	1.00
122_P	126_I	1.314	1.00
48_L	254_F	1.309	1.00
167_I	251_C	1.300	1.00
287_L	291_C	1.294	1.00
86_I	90_A	1.293	1.00
443_C	447_I	1.286	1.00
247_I	251_C	1.278	1.00
18_H	149_G	1.274	1.00
176_G	179_P	1.271	1.00
16_S	236_R	1.269	1.00
34_V	112_I	1.268	1.00
113_A	294_L	1.264	1.00
416_F	420_V	1.263	1.00
230_P	235_V	1.262	1.00
61_I	379_A	1.261	1.00
62_M	238_T	1.261	1.00
14_L	19_V	1.258	1.00
233_H	236_R	1.255	1.00
27_V	245_I	1.253	1.00
71_A	396_I	1.253	1.00
174_I	258_A	1.252	1.00
89_W	449_A	1.249	1.00
113_A	133_I	1.245	1.00
435_G	439_I	1.242	1.00
85_A	381_S	1.235	1.00
434_T	441_I	1.230	1.00
137_L	301_L	1.224	1.00
376_L	415_T	1.219	1.00
80_T	84_K	1.214	1.00
435_G	444_T	1.199	1.00
14_L	149_G	1.198	1.00
312_L	321_A	1.188	1.00
63_R	239_N	1.183	1.00
271_G	275_S	1.172	1.00
140_S	151_F	1.168	1.00
64_M	407_T	1.167	1.00
17_R	21_M	1.166	1.00
433_S	444_T	1.158	1.00
436_L	441_I	1.155	1.00
402_L	406_L	1.154	1.00
99_W	312_L	1.149	1.00
166_F	170_G	1.147	1.00
444_T	447_I	1.141	1.00
40_I	47_V	1.133	1.00
127_W	131_L	1.132	1.00
109_E	300_C	1.122	1.00
65_L	78_F	1.120	1.00
262_W	265_P	1.119	1.00
404_P	408_W	1.117	1.00
278_E	283_P	1.114	1.00
435_G	438_A	1.108	1.00
228_D	233_H	1.105	1.00
19_V	237_A	1.105	1.00
74_D	80_T	1.103	1.00
193_G	197_P	1.095	1.00
405_W	408_W	1.087	1.00
150_E	154_W	1.085	1.00
46_A	203_V	1.084	1.00
92_Y	96_W	1.082	1.00
387_K	404_P	1.079	1.00
152_E	302_N	1.073	1.00
403_Y	407_T	1.067	1.00
393_G	396_I	1.067	1.00
23_S	220_V	1.065	1.00
13_G	228_D	1.059	1.00
392_E	396_I	1.055	1.00
183_V	186_I	1.054	1.00
82_A	90_A	1.050	1.00
445_V	448_M	1.049	1.00
165_A	169_L	1.044	1.00
382_Q	407_T	1.043	1.00
125_P	128_L	1.041	1.00
444_T	449_A	1.038	1.00
317_R	326_G	1.037	1.00
151_F	155_L	1.034	1.00
128_L	132_V	1.034	1.00
438_A	445_V	1.034	1.00
343_G	347_L	1.031	1.00
434_T	440_G	1.030	1.00
22_L	223_A	1.030	1.00
171_A	175_S	1.029	1.00
434_T	437_L	1.025	1.00
170_G	259_L	1.025	1.00
67_E	70_V	1.023	1.00
79_S	314_S	1.023	1.00
394_S	397_R	1.020	1.00
69_A	81_Y	1.019	1.00
379_A	411_I	1.015	1.00
132_V	136_A	1.014	1.00
328_I	332_K	1.014	1.00
336_V	339_L	1.012	1.00
114_A	129_F	1.009	1.00
52_L	250_L	1.007	1.00
204_L	416_F	1.007	1.00
24_I	245_I	1.006	1.00
24_I	244_R	1.004	1.00
436_L	444_T	1.002	1.00
434_T	445_V	0.996	1.00
84_K	391_A	0.996	1.00
138_T	142_L	0.996	1.00
224_A	234_I	0.993	1.00
135_L	139_G	0.990	1.00
60_M	406_L	0.988	1.00
145_V	306_Y	0.987	1.00
199_G	202_A	0.987	1.00
433_S	441_I	0.983	1.00
411_I	415_T	0.983	1.00
175_S	179_P	0.982	1.00
439_I	442_I	0.982	1.00
437_L	444_T	0.979	1.00
435_G	440_G	0.975	1.00
164_L	168_F	0.975	1.00
117_L	294_L	0.972	1.00
71_A	394_S	0.972	1.00
438_A	443_C	0.972	1.00
160_V	248_F	0.971	1.00
402_L	405_W	0.966	1.00
422_L	426_A	0.965	1.00
74_D	84_K	0.959	1.00
376_L	414_I	0.957	1.00
167_I	255_V	0.957	1.00
391_A	394_S	0.955	1.00
283_P	287_L	0.948	1.00
196_M	203_V	0.948	1.00
172_V	176_G	0.946	1.00
433_S	437_L	0.940	1.00
166_F	277_L	0.939	1.00
114_A	130_S	0.937	1.00
415_T	419_V	0.937	1.00
246_S	250_L	0.935	1.00
218_E	222_I	0.932	1.00
142_L	333_T	0.931	1.00
395_E	399_R	0.931	1.00
136_A	298_T	0.928	1.00
137_L	302_N	0.926	1.00
437_L	440_G	0.923	1.00
281_N	285_A	0.918	1.00
335_Y	339_L	0.915	1.00
441_I	444_T	0.915	1.00
21_M	153_F	0.911	1.00
261_P	279_L	0.911	1.00
175_S	178_Y	0.911	1.00
215_M	371_A	0.910	1.00
419_V	423_F	0.908	1.00
48_L	257_V	0.906	1.00
396_I	399_R	0.904	1.00
240_S	244_R	0.902	1.00
259_L	276_V	0.899	1.00
76_G	80_T	0.894	1.00
305_L	342_T	0.888	1.00
117_L	121_V	0.887	1.00
282_I	285_A	0.885	1.00
442_I	445_V	0.881	1.00
422_L	425_P	0.880	1.00
55_G	214_F	0.877	1.00
443_C	446_P	0.876	1.00
437_L	442_I	0.874	1.00
155_L	299_S	0.870	1.00
42_E	45_P	0.865	1.00
436_L	439_I	0.861	1.00
52_L	56_L	0.861	1.00
70_V	397_R	0.859	1.00
159_K	296_S	0.859	1.00
254_F	258_A	0.857	1.00
61_I	414_I	0.857	1.00
124_I	128_L	0.856	1.00
329_N	332_K	0.856	1.00
13_G	146_K	0.854	1.00
434_T	443_C	0.853	1.00
68_M	382_Q	0.850	1.00
142_L	329_N	0.850	1.00
10_L	226_E	0.848	1.00
325_M	336_V	0.847	1.00
436_L	445_V	0.847	1.00
403_Y	406_L	0.844	1.00
18_H	150_E	0.843	1.00
418_L	426_A	0.842	1.00
433_S	438_A	0.841	1.00
83_D	318_R	0.839	1.00
150_E	153_F	0.839	1.00
108_L	364_I	0.839	1.00
108_L	212_F	0.838	1.00
28_I	31_S	0.838	1.00
269_A	272_S	0.838	1.00
435_G	445_V	0.837	1.00
376_L	380_V	0.832	1.00
446_P	449_A	0.831	1.00
321_A	325_M	0.831	1.00
418_L	421_M	0.827	1.00
10_L	310_R	0.826	1.00
342_T	346_F	0.823	1.00
441_I	449_A	0.822	1.00
172_V	177_F	0.821	1.00
196_M	199_G	0.816	1.00
129_F	132_V	0.813	1.00
383_L	407_T	0.811	1.00
123_G	126_I	0.810	1.00
17_R	153_F	0.810	1.00
82_A	381_S	0.810	1.00
205_S	209_I	0.807	1.00
200_F	203_V	0.806	1.00
16_S	237_A	0.806	1.00
59_V	63_R	0.805	1.00
410_V	414_I	0.805	1.00
395_E	398_L	0.804	1.00
134_T	349_V	0.804	1.00
167_I	171_A	0.803	1.00
113_A	298_T	0.803	1.00
264_M	267_L	0.799	1.00
127_W	349_V	0.798	1.00
76_G	79_S	0.795	1.00
96_W	321_A	0.792	1.00
219_I	307_T	0.791	1.00
439_I	443_C	0.787	1.00
438_A	444_T	0.786	1.00
425_P	428_Q	0.784	1.00
441_I	446_P	0.782	1.00
113_A	297_V	0.782	1.00
71_A	397_R	0.781	1.00
98_Y	102_W	0.780	1.00
90_A	377_V	0.779	1.00
435_G	441_I	0.777	1.00
277_L	280_L	0.774	1.00
139_G	142_L	0.771	1.00
49_L	203_V	0.770	1.00
28_I	159_K	0.770	1.00
383_L	404_P	0.767	1.00
171_A	251_C	0.766	1.00
215_M	375_Y	0.766	1.00
111_N	363_L	0.766	1.00
416_F	419_V	0.765	1.00
59_V	239_N	0.764	1.00
436_L	443_C	0.762	1.00
137_L	305_L	0.762	1.00
434_T	442_I	0.760	1.00
60_M	64_M	0.757	1.00
191_D	194_G	0.755	1.00
89_W	93_T	0.753	1.00
143_L	147_N	0.742	1.00
417_V	421_M	0.739	1.00
32_L	252_S	0.735	1.00
186_I	258_A	0.734	1.00
438_A	448_M	0.733	1.00
20_T	237_A	0.732	1.00
127_W	130_S	0.724	1.00
229_T	235_V	0.721	1.00
272_S	276_V	0.720	1.00
174_I	255_V	0.718	1.00
142_L	331_S	0.714	1.00
79_S	83_D	0.711	1.00
324_V	340_L	0.709	1.00
330_R	335_Y	0.708	1.00
383_L	387_K	0.708	1.00
13_G	145_V	0.707	1.00
310_R	313_Y	0.706	1.00
366_S	370_I	0.706	1.00
103_V	344_A	0.704	1.00
235_V	238_T	0.704	1.00
68_M	81_Y	0.703	1.00
440_G	445_V	0.702	1.00
114_A	117_L	0.701	1.00
443_C	449_A	0.700	1.00
149_G	153_F	0.698	1.00
433_S	442_I	0.698	1.00
271_G	274_R	0.697	1.00
334_P	337_A	0.697	1.00
85_A	384_R	0.696	1.00
190_W	193_G	0.696	1.00
105_V	367_S	0.695	1.00
414_I	417_V	0.695	1.00
439_I	446_P	0.695	1.00
49_L	53_F	0.691	1.00
381_S	385_M	0.690	1.00
167_I	252_S	0.689	1.00
64_M	410_V	0.686	1.00
441_I	447_I	0.685	1.00
424_R	428_Q	0.684	1.00
107_P	363_L	0.683	1.00
17_R	150_E	0.683	1.00
402_L	407_T	0.683	1.00
58_V	217_A	0.680	1.00
131_L	350_V	0.678	1.00
86_I	381_S	0.677	1.00
305_L	309_S	0.675	1.00
195_F	198_N	0.675	1.00
172_V	175_S	0.675	1.00
343_G	346_F	0.673	1.00
141_N	338_V	0.673	1.00
436_L	449_A	0.673	1.00
435_G	442_I	0.667	1.00
110_A	114_A	0.666	1.00
382_Q	386_R	0.666	1.00
75_T	313_Y	0.665	1.00
28_I	33_F	0.665	1.00
36_S	253_I	0.664	1.00
398_L	401_W	0.663	1.00
284_H	287_L	0.662	1.00
137_L	298_T	0.661	1.00
45_P	257_V	0.661	1.00
25_A	156_A	0.660	1.00
101_F	371_A	0.659	1.00
325_M	337_A	0.658	1.00
309_S	337_A	0.657	1.00
105_V	108_L	0.657	1.00
105_V	109_E	0.656	1.00
46_A	195_F	0.656	1.00
394_S	399_R	0.655	1.00
60_M	410_V	0.654	1.00
372_L	414_I	0.653	1.00
410_V	413_F	0.651	1.00
244_R	248_F	0.650	1.00
135_L	138_T	0.649	1.00
387_K	391_A	0.649	1.00
10_L	13_G	0.648	1.00
141_N	306_Y	0.648	1.00
49_L	52_L	0.647	1.00
29_G	33_F	0.646	1.00
65_L	378_I	0.645	1.00
437_L	445_V	0.644	1.00
312_L	340_L	0.644	1.00
87_G	91_G	0.644	1.00
142_L	338_V	0.640	1.00
439_I	445_V	0.640	1.00
200_F	204_L	0.639	1.00
13_G	17_R	0.639	1.00
434_T	439_I	0.639	1.00
85_A	385_M	0.636	1.00
234_I	238_T	0.636	1.00
204_L	420_V	0.635	1.00
202_A	205_S	0.635	1.00
96_W	440_G	0.633	1.00
104_L	366_S	0.632	1.00
69_A	234_I	0.629	1.00
221_T	238_T	0.629	1.00
414_I	418_L	0.629	1.00
144_S	147_N	0.628	1.00
117_L	133_I	0.628	1.00
62_M	217_A	0.627	1.00
53_F	207_M	0.626	1.00
147_N	150_E	0.625	1.00
316_S	325_M	0.625	1.00
68_M	85_A	0.624	1.00
27_V	241_V	0.624	1.00
133_I	301_L	0.622	1.00
396_I	400_M	0.622	1.00
273_Y	277_L	0.621	1.00
435_G	449_A	0.621	1.00
272_S	275_S	0.621	1.00
175_S	183_V	0.620	1.00
120_W	291_C	0.620	1.00
225_A	313_Y	0.619	1.00
386_R	403_Y	0.619	1.00
240_S	243_W	0.619	1.00
158_C	292_V	0.618	1.00
39_A	43_A	0.618	1.00
134_T	346_F	0.617	1.00
26_G	303_S	0.614	1.00
436_L	448_M	0.614	1.00
263_N	267_L	0.614	1.00
169_L	282_I	0.614	1.00
66_A	70_V	0.614	1.00
48_L	250_L	0.612	1.00
20_T	23_S	0.611	1.00
48_L	52_L	0.610	1.00
215_M	218_E	0.610	1.00
370_I	374_V	0.607	1.00
194_G	197_P	0.607	1.00
35_G	364_I	0.604	1.00
369_A	418_L	0.603	1.00
78_F	218_E	0.602	1.00
116_I	293_I	0.601	1.00
434_T	444_T	0.600	1.00
107_P	348_T	0.600	1.00
193_G	196_M	0.600	1.00
169_L	173_A	0.600	1.00
47_V	253_I	0.600	1.00
291_C	295_L	0.599	1.00
79_S	95_G	0.597	1.00
442_I	449_A	0.596	1.00
231_E	397_R	0.596	1.00
45_P	48_L	0.595	1.00
296_S	299_S	0.593	1.00
97_L	374_V	0.593	1.00
433_S	446_P	0.592	1.00
308_A	312_L	0.591	1.00
401_W	405_W	0.591	1.00
251_C	255_V	0.591	1.00
102_W	304_A	0.590	1.00
26_G	304_A	0.589	1.00
222_I	307_T	0.587	1.00
226_E	334_P	0.586	1.00
433_S	447_I	0.586	1.00
404_P	407_T	0.584	1.00
244_R	247_I	0.583	1.00
388_I	391_A	0.583	1.00
28_I	248_F	0.581	1.00
158_C	162_A	0.581	1.00
71_A	392_E	0.579	1.00
145_V	223_A	0.579	1.00
24_I	156_A	0.578	1.00
227_S	234_I	0.578	1.00
48_L	51_Y	0.576	1.00
156_A	159_K	0.576	1.00
54_A	214_F	0.575	1.00
69_A	221_T	0.573	1.00
421_M	425_P	0.572	1.00
38_V	361_K	0.572	1.00
109_E	112_I	0.570	1.00
423_F	426_A	0.569	1.00
324_V	328_I	0.569	1.00
54_A	211_M	0.568	1.00
51_Y	213_S	0.567	1.00
77_S	221_T	0.565	1.00
394_S	398_L	0.565	1.00
376_L	418_L	0.564	1.00
192_S	263_N	0.563	1.00
417_V	422_L	0.563	1.00
79_S	91_G	0.562	1.00
148_Y	306_Y	0.562	1.00
78_F	222_I	0.561	1.00
262_W	266_G	0.560	1.00
419_V	422_L	0.560	1.00
112_I	116_I	0.559	1.00
440_G	447_I	0.559	1.00
213_S	249_Y	0.559	1.00
43_A	46_A	0.558	1.00
407_T	411_I	0.558	1.00
328_I	331_S	0.558	1.00
38_V	41_A	0.558	1.00
119_S	290_D	0.558	1.00
438_A	449_A	0.557	1.00
107_P	110_A	0.556	1.00
138_T	305_L	0.555	1.00
147_N	151_F	0.555	1.00
39_A	206_A	0.554	1.00
63_R	406_L	0.553	1.00
103_V	341_S	0.551	1.00
400_M	403_Y	0.550	1.00
109_E	297_V	0.548	1.00
230_P	233_H	0.548	1.00
400_M	406_L	0.546	1.00
272_S	277_L	0.546	1.00
29_G	249_Y	0.545	1.00
23_S	27_V	0.544	1.00
63_R	401_W	0.543	1.00
133_I	137_L	0.543	1.00
252_S	256_V	0.542	1.00
153_F	157_L	0.542	1.00
109_E	301_L	0.542	1.00
191_D	195_F	0.540	1.00
383_L	411_I	0.537	1.00
132_V	135_L	0.537	1.00
62_M	66_A	0.536	1.00
26_G	219_I	0.536	1.00
152_E	299_S	0.535	1.00
440_G	449_A	0.535	1.00
371_A	374_V	0.534	1.00
42_E	205_S	0.534	1.00
412_G	415_T	0.532	1.00
408_W	411_I	0.532	1.00
38_V	42_E	0.532	1.00
94_I	374_V	0.531	1.00
17_R	20_T	0.530	1.00
28_I	35_G	0.530	1.00
149_G	302_N	0.530	1.00
120_W	290_D	0.528	1.00
397_R	400_M	0.524	1.00
97_L	101_F	0.524	1.00
255_V	258_A	0.522	1.00
312_L	316_S	0.522	1.00
392_E	395_E	0.522	1.00
260_I	264_M	0.521	1.00
420_V	424_R	0.521	1.00
350_V	353_Y	0.520	1.00
113_A	117_L	0.520	1.00
154_W	157_L	0.519	1.00
436_L	447_I	0.517	1.00
283_P	286_K	0.517	1.00
34_V	37_S	0.516	1.00
288_I	292_V	0.516	1.00
121_V	124_I	0.515	1.00
227_S	237_A	0.515	1.00
310_R	334_P	0.514	1.00
110_A	113_A	0.514	1.00
161_I	164_L	0.514	1.00
39_A	210_T	0.513	1.00
442_I	447_I	0.512	1.00
36_S	256_V	0.512	1.00
51_Y	253_I	0.511	1.00
162_A	288_I	0.511	1.00
347_L	350_V	0.510	1.00
136_A	140_S	0.509	1.00
252_S	273_Y	0.509	1.00
153_F	156_A	0.508	1.00
19_V	223_A	0.507	1.00
335_Y	338_V	0.507	1.00
361_K	364_I	0.505	1.00
263_N	266_G	0.505	1.00
67_E	71_A	0.503	1.00
436_L	446_P	0.503	1.00
51_Y	249_Y	0.503	1.00
71_A	385_M	0.502	1.00
61_I	218_E	0.501	1.00
436_L	442_I	0.501	1.00
46_A	49_L	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8948	100	0.297	Contact Map
4djkA	2	0.8906	100	0.332	Contact Map
3giaA	1	0.9142	100	0.338	Contact Map
3dh4A	3	0.9206	98.9	0.856	Contact Map
2xq2A	2	0.9227	98.9	0.856	Contact Map
2jlnA	1	0.8927	98.4	0.88	Contact Map
4wgvA	2	0.7918	97.7	0.898	Contact Map
4xp4A	1	0.9227	96.9	0.911	Contact Map
4us3A	1	0.8433	96.7	0.913	Contact Map
2a65A	2	0.927	96.5	0.915	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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