GREMLIN Database
TEHA - Tellurite resistance protein TehA
UniProt: P25396 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11883
Length: 330 (304)
Sequences: 2181 (1613)
Seq/√Len: 92.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
156_C165_G5.7491.00
63_L70_V4.6861.00
231_F271_G4.6051.00
261_S301_L4.2171.00
71_L75_R3.7031.00
22_G265_S3.6221.00
212_C270_T3.3931.00
17_V89_T3.1971.00
27_W295_N3.0981.00
209_L234_G3.0931.00
304_R307_A3.0891.00
68_H71_L2.9411.00
231_F274_L2.6811.00
20_T298_I2.6361.00
21_I92_L2.5231.00
150_F172_G2.5201.00
91_M112_G2.4641.00
61_A65_R2.4331.00
265_S298_I2.4301.00
238_L267_L2.4211.00
52_W90_T2.3791.00
170_G232_G2.2711.00
107_C111_F2.2641.00
97_F104_L2.2361.00
296_F300_I2.2361.00
46_I50_I2.0801.00
109_F156_C2.0551.00
39_W43_G2.0421.00
45_V96_G2.0241.00
166_L219_N2.0091.00
272_L287_A1.9981.00
307_A311_Q1.9361.00
166_L218_V1.9261.00
20_T51_I1.9241.00
56_T86_F1.9201.00
60_I64_I1.8771.00
15_G85_L1.8001.00
21_I48_A1.7621.00
235_L267_L1.7421.00
27_W291_F1.7241.00
137_T141_L1.7111.00
300_I304_R1.6721.00
212_C227_A1.6651.00
150_F211_A1.6371.00
24_G96_G1.6201.00
98_V105_A1.6021.00
273_H276_S1.5891.00
60_I63_L1.5801.00
74_V83_V1.5501.00
94_A112_G1.5491.00
258_W305_T1.5421.00
26_A291_F1.5411.00
67_P71_L1.5361.00
19_G261_S1.5341.00
22_G269_T1.5171.00
306_F310_M1.4901.00
292_I296_F1.4881.00
24_G41_G1.4801.00
164_A167_V1.4791.00
81_S140_G1.4711.00
199_T260_F1.4360.99
299_A303_I1.4270.99
18_L85_L1.4270.99
23_M44_L1.4250.99
210_V266_A1.4200.99
49_M93_V1.4190.99
88_A210_V1.4090.99
87_P116_Q1.4080.99
51_I55_L1.3880.99
146_V210_V1.3840.99
43_G47_L1.3800.99
223_G226_L1.3760.99
217_S273_H1.3660.99
95_I155_A1.3650.99
12_G15_G1.3470.99
238_L264_V1.3340.99
10_P13_Y1.3310.99
303_I307_A1.3190.99
205_L238_L1.3030.99
185_Q189_S1.3030.99
215_W226_L1.2890.99
173_V230_L1.2810.99
231_F267_L1.2800.99
25_F95_I1.2750.99
9_L13_Y1.2640.99
38_H42_D1.2600.99
291_F295_N1.2600.99
104_L107_C1.2590.99
39_W42_D1.2540.99
30_A291_F1.2540.99
268_A294_T1.2410.98
194_P197_L1.2320.98
14_F56_T1.2290.98
28_R41_G1.2250.98
153_A214_A1.2230.98
264_V297_I1.2100.98
76_H186_R1.1860.98
268_A290_L1.1840.98
62_R73_E1.1810.98
16_I55_L1.1800.98
30_A288_V1.1790.98
41_G100_W1.1720.98
17_V51_I1.1700.98
49_M53_G1.1600.98
44_L295_N1.1600.98
59_F62_R1.1520.97
176_W207_P1.1510.97
235_L286_L1.1380.97
24_G48_A1.1310.97
307_A310_M1.1300.97
119_Y147_A1.1290.97
24_G45_V1.1260.97
200_S256_S1.1250.97
85_L143_L1.1200.97
16_I302_L1.1200.97
176_W208_A1.1190.97
64_I67_P1.1180.97
177_L181_P1.1110.97
53_G56_T1.1050.97
205_L267_L1.1040.97
216_L227_A1.0920.97
88_A146_V1.0890.96
177_L221_G1.0880.96
103_P191_G1.0870.96
169_L214_A1.0800.96
152_S155_A1.0670.96
106_V110_S1.0650.96
74_V122_W1.0610.96
142_Y180_E1.0610.96
111_F115_V1.0600.96
9_L58_A1.0580.96
43_G46_I1.0570.96
76_H80_S1.0570.96
40_L43_G1.0530.96
87_P115_V1.0490.96
220_G276_S1.0460.96
157_G217_S1.0410.95
90_T108_L1.0340.95
121_A239_L1.0320.95
124_T145_T1.0320.95
19_G151_I1.0240.95
151_I261_S1.0240.95
120_A181_P1.0230.95
94_A105_A1.0210.95
88_A266_A1.0170.95
36_V40_L1.0140.95
49_M97_F1.0040.94
239_L293_F1.0020.94
268_A272_L1.0000.94
84_S87_P0.9990.94
281_G284_H0.9940.94
176_W181_P0.9910.94
119_Y199_T0.9810.94
103_P107_C0.9800.94
271_G290_L0.9800.94
91_M151_I0.9730.93
16_I305_T0.9720.93
62_R70_V0.9680.93
113_V151_I0.9670.93
137_T182_V0.9610.93
27_W30_A0.9570.93
275_G287_A0.9570.93
275_G284_H0.9550.93
282_F286_L0.9530.93
261_S298_I0.9500.93
134_E186_R0.9390.92
202_G245_M0.9380.92
116_Q147_A0.9350.92
302_L309_L0.9340.92
42_D100_W0.9310.92
107_C110_S0.9290.92
9_L55_L0.9280.92
302_L306_F0.9230.92
61_A279_D0.9160.91
204_Q207_P0.9140.91
50_I54_L0.9140.91
279_D284_H0.9140.91
267_L290_L0.9110.91
153_A157_G0.9090.91
25_F269_T0.9070.91
61_A64_I0.9070.91
98_V102_R0.9070.91
183_I204_Q0.9050.91
271_G286_L0.9030.91
275_G283_F0.8980.90
58_A65_R0.8970.90
64_I117_L0.8950.90
235_L290_L0.8930.90
116_Q148_N0.8920.90
183_I187_L0.8840.90
15_G25_F0.8810.90
77_P187_L0.8790.89
234_G267_L0.8780.89
81_S138_T0.8770.89
113_V152_S0.8730.89
232_G235_L0.8690.89
61_A190_S0.8680.89
120_A148_N0.8630.89
284_H288_V0.8630.89
30_A287_A0.8590.88
29_Y114_V0.8580.88
57_S61_A0.8500.88
143_L152_S0.8490.88
285_T289_P0.8470.88
39_W103_P0.8460.88
178_S184_L0.8440.87
15_G26_A0.8410.87
39_W284_H0.8410.87
116_Q152_S0.8400.87
27_W37_S0.8390.87
107_C285_T0.8380.87
70_V83_V0.8310.87
142_Y179_L0.8280.86
174_F229_M0.8240.86
209_L213_S0.8180.86
14_F258_W0.8170.86
14_F17_V0.8130.85
50_I53_G0.8130.85
6_V61_A0.8120.85
88_A109_F0.8090.85
59_F63_L0.8090.85
64_I292_I0.8080.85
252_P304_R0.8050.85
275_G278_S0.8020.85
116_Q206_A0.8010.85
268_A291_F0.7980.84
105_A159_L0.7980.84
35_Q164_A0.7970.84
121_A124_T0.7960.84
84_S88_A0.7920.84
76_H197_L0.7910.84
187_L191_G0.7890.84
7_L66_F0.7880.84
26_A269_T0.7820.83
88_A151_I0.7790.83
209_L266_A0.7750.83
231_F237_Q0.7730.82
62_R200_S0.7720.82
201_L207_P0.7720.82
282_F285_T0.7720.82
111_F284_H0.7710.82
134_E185_Q0.7680.82
75_R126_G0.7660.82
186_R270_T0.7620.82
153_A165_G0.7550.81
199_T251_Q0.7550.81
63_L67_P0.7550.81
93_V114_V0.7530.81
303_I306_F0.7530.81
93_V97_F0.7500.81
166_L194_P0.7470.80
91_M94_A0.7470.80
175_S236_L0.7440.80
80_S123_Q0.7440.80
80_S248_Y0.7390.80
211_A234_G0.7370.79
217_S221_G0.7350.79
180_E204_Q0.7330.79
6_V66_F0.7320.79
90_T112_G0.7310.79
52_W93_V0.7310.79
216_L277_G0.7300.79
174_F293_F0.7290.79
109_F155_A0.7280.79
176_W180_E0.7250.78
14_F59_F0.7190.78
51_I71_L0.7190.78
154_M210_V0.7180.78
38_H114_V0.7180.78
11_A14_F0.7170.77
39_W60_I0.7170.77
51_I302_L0.7160.77
163_D228_K0.7150.77
19_G144_P0.7130.77
103_P106_V0.7130.77
283_F286_L0.7120.77
275_G280_N0.7120.77
281_G285_T0.7100.77
228_K278_S0.7070.76
178_S230_L0.7060.76
41_G96_G0.7060.76
59_F70_V0.7040.76
152_S168_F0.6970.75
32_Q110_S0.6950.75
144_P207_P0.6910.75
54_L57_S0.6910.75
11_A73_E0.6900.75
57_S60_I0.6900.75
58_A62_R0.6860.74
170_G233_Y0.6860.74
87_P112_G0.6830.74
25_F234_G0.6820.74
77_P186_R0.6800.74
19_G146_V0.6780.73
169_L173_V0.6770.73
308_L311_Q0.6760.73
14_F85_L0.6740.73
129_R240_F0.6740.73
289_P293_F0.6710.73
112_G146_V0.6690.72
174_F232_G0.6680.72
89_T92_L0.6670.72
84_S207_P0.6660.72
21_I298_I0.6650.72
211_A226_L0.6640.72
6_V65_R0.6630.72
242_L293_F0.6620.72
202_G206_A0.6620.72
13_Y16_I0.6620.72
94_A155_A0.6610.72
135_E191_G0.6600.71
23_M298_I0.6570.71
98_V159_L0.6560.71
69_S72_A0.6550.71
7_L69_S0.6540.71
107_C303_I0.6520.71
142_Y176_W0.6510.70
40_L284_H0.6500.70
237_Q241_M0.6460.70
107_C225_T0.6450.70
182_V185_Q0.6450.70
169_L210_V0.6420.69
60_I86_F0.6410.69
63_L309_L0.6400.69
253_F301_L0.6400.69
45_V48_A0.6390.69
27_W40_L0.6390.69
84_S144_P0.6380.69
41_G115_V0.6380.69
197_L264_V0.6340.68
31_S41_G0.6320.68
178_S303_I0.6300.68
206_A298_I0.6290.68
207_P237_Q0.6260.67
35_Q54_L0.6260.67
129_R268_A0.6250.67
145_T179_L0.6250.67
10_P15_G0.6250.67
25_F48_A0.6240.67
153_A218_V0.6220.67
154_M217_S0.6220.67
143_L147_A0.6190.67
158_A303_I0.6190.67
150_F214_A0.6180.66
158_A161_Y0.6170.66
40_L288_V0.6160.66
46_I49_M0.6160.66
47_L310_M0.6150.66
89_T191_G0.6150.66
53_G57_S0.6140.66
19_G305_T0.6090.65
245_M249_L0.6080.65
64_I297_I0.6080.65
105_A158_A0.6070.65
210_V265_S0.6060.65
118_A121_A0.6050.65
90_T111_F0.6030.65
48_A52_W0.6010.64
143_L212_C0.6010.64
68_H133_P0.6000.64
222_E226_L0.6000.64
72_A104_L0.5980.64
104_L289_P0.5980.64
18_L202_G0.5980.64
81_S127_L0.5980.64
71_L119_Y0.5970.64
142_Y270_T0.5970.64
120_A137_T0.5950.64
297_I300_I0.5940.63
8_N159_L0.5920.63
299_A302_L0.5890.63
88_A261_S0.5890.63
299_A304_R0.5870.62
248_Y260_F0.5860.62
16_I183_I0.5840.62
22_G25_F0.5830.62
135_E189_S0.5830.62
202_G208_A0.5830.62
233_Y273_H0.5810.62
119_Y209_L0.5810.62
104_L276_S0.5810.62
137_T183_I0.5780.61
55_L58_A0.5760.61
282_F307_A0.5760.61
249_L269_T0.5760.61
60_I107_C0.5750.61
154_M213_S0.5740.61
172_G208_A0.5740.61
96_G100_W0.5740.61
111_F279_D0.5720.60
82_F255_A0.5690.60
255_A294_T0.5690.60
240_F244_L0.5680.60
232_G274_L0.5670.60
9_L309_L0.5660.60
109_F150_F0.5660.60
9_L62_R0.5650.60
145_T175_S0.5650.60
50_I296_F0.5630.59
145_T242_L0.5620.59
150_F207_P0.5610.59
226_L253_F0.5600.59
113_V168_F0.5600.59
128_W237_Q0.5600.59
22_G206_A0.5600.59
21_I172_G0.5590.59
142_Y147_A0.5580.59
100_W123_Q0.5570.58
150_F153_A0.5570.58
116_Q119_Y0.5570.58
242_L310_M0.5570.58
163_D283_F0.5540.58
231_F236_L0.5540.58
28_R99_P0.5520.58
91_M155_A0.5520.58
80_S247_W0.5470.57
213_S273_H0.5460.57
199_T257_F0.5460.57
39_W296_F0.5460.57
50_I118_A0.5440.57
139_P183_I0.5430.57
98_V158_A0.5420.56
131_S164_A0.5400.56
215_W227_A0.5380.56
111_F114_V0.5360.56
57_S300_I0.5350.55
23_M295_N0.5330.55
60_I71_L0.5310.55
155_A235_L0.5290.55
276_S284_H0.5290.55
285_T303_I0.5280.54
120_A144_P0.5270.54
31_S37_S0.5260.54
248_Y252_P0.5260.54
28_R42_D0.5250.54
219_N223_G0.5240.54
97_F112_G0.5230.54
157_G218_V0.5180.53
64_I68_H0.5180.53
130_G134_E0.5180.53
67_P164_A0.5180.53
59_F73_E0.5170.53
253_F257_F0.5170.53
205_L209_L0.5170.53
123_Q171_A0.5170.53
56_T60_I0.5110.52
64_I111_F0.5090.52
235_L239_L0.5070.52
281_G293_F0.5050.51
71_L74_V0.5050.51
118_A276_S0.5050.51
137_T185_Q0.5040.51
11_A83_V0.5040.51
84_S176_W0.5030.51
121_A238_L0.5020.51
76_H81_S0.5000.51
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3m73A 3 0.9364 100 0.155 Contact Map
3giaA 1 0.9152 23.9 0.956 Contact Map
2kncA 1 0.1606 12.5 0.961 Contact Map
3rvyA 3 0.6606 10.4 0.962 Contact Map
2cfqA 1 0.5909 9.2 0.963 Contact Map
3pjsK 4 0.3273 8.9 0.964 Contact Map
4tphA 2 0.5697 8.6 0.964 Contact Map
4kjrA 3 0.4667 8.5 0.964 Contact Map
3vouA 4 0.3697 6.9 0.965 Contact Map
2h8aA 3 0.1121 6.7 0.966 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.009 seconds.