ASCB - ECOLI - GREMLIN Contacts

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ASCB - 6-phospho-beta-glucosidase AscB

UniProt:	P24240	Sequences: MSVFPESFLWGGALAANQSEGAFREGDKGLTTVDMIPHGEHRMAVKLGLEKRFQLRDDEFYPSHEATDFYHRYKEDIALMAEMGFKVFRTSIAWSRLFPQGDEITPNQQGIAFYRSVFEECKKYGIEPLVTLCHFDVPMHLVTEYGSWRNRKLVEFFSRYARTCFEAFDGLVKYWLTFNEINIMLHSPFSGAGLVFEEGENQDQVKYQAAHHQLVASALATKIAHEVNPQNQVGCMLAGGNFYPYSCKPEDVWAALEKDRENLFFIDVQARGTYPAYSARVFREKGVTINKAPGDDEILKNTVDFVSFSYYASRCASAEMNANNSSAANVVKSLRNPYLQVSDWGWGIDPLGLRITMNMMYDRYQKPLFLVENGLGAKDEFAANGEINDDYRISYLREHIRAMGEAIADGIPLMGYTTWGCIDLVSASTGEMSKRYGFVFVDRDDAGNGTLTRTRKKSFWWYKKVIASNGEDLE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10085
Length:	474 (440)
Sequences:	6780 (4222)
Seq/√Len:	201.3

ECOLI - ASCB BGLB BGLA
BACSU - BGLA BGLH BGLC GMUD
SULSO - BGAL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
26_G	109_Q	4.313	1.00
388_N	457_K	4.067	1.00
119_E	171_L	3.642	1.00
403_M	413_L	3.181	1.00
115_R	171_L	3.174	1.00
81_A	124_Y	3.104	1.00
74_K	120_E	3.033	1.00
57_D	61_Y	2.947	1.00
115_R	167_A	2.946	1.00
132_L	164_C	2.930	1.00
120_E	123_K	2.906	1.00
455_R	459_F	2.892	1.00
108_Q	112_A	2.860	1.00
68_D	71_H	2.832	1.00
112_A	116_S	2.794	1.00
108_Q	167_A	2.760	1.00
98_F	163_T	2.693	1.00
402_A	405_E	2.678	1.00
310_Y	399_H	2.674	1.00
246_S	251_D	2.637	1.00
162_R	166_E	2.598	1.00
25_E	71_H	2.551	1.00
12_G	85_F	2.468	1.00
396_L	418_T	2.356	1.00
354_R	409_D	2.314	1.00
358_N	409_D	2.274	1.00
151_R	295_D	2.273	1.00
78_A	124_Y	2.270	1.00
394_S	398_E	2.250	1.00
155_E	219_L	2.234	1.00
38_H	64_H	2.234	1.00
224_A	233_V	2.220	1.00
222_K	226_E	2.178	1.00
440_F	454_T	2.178	1.00
69_F	113_F	2.148	1.00
118_F	168_F	2.147	1.00
74_K	116_S	2.128	1.00
390_D	457_K	2.126	1.00
87_V	417_T	2.101	1.00
77_I	117_V	2.049	1.00
127_E	173_K	2.044	1.00
69_F	88_F	2.019	1.00
463_K	467_A	1.986	1.00
92_I	130_V	1.979	1.00
382_A	386_E	1.971	1.00
122_K	171_L	1.957	1.00
158_S	223_I	1.934	1.00
294_G	297_E	1.929	1.00
35_M	139_M	1.920	1.00
211_H	274_Y	1.913	1.00
109_Q	112_A	1.895	1.00
90_T	118_F	1.887	1.00
162_R	223_I	1.878	1.00
162_R	227_V	1.871	1.00
31_T	95_S	1.857	1.00
276_A	280_R	1.851	1.00
77_I	124_Y	1.834	1.00
23_F	30_L	1.813	1.00
224_A	231_N	1.798	1.00
115_R	119_E	1.796	1.00
354_R	405_E	1.787	1.00
22_A	25_E	1.783	1.00
243_Y	355_I	1.765	1.00
30_L	35_M	1.764	1.00
10_W	469_N	1.714	1.00
219_L	298_I	1.706	1.00
14_L	19_S	1.688	1.00
119_E	122_K	1.684	1.00
120_E	124_Y	1.682	1.00
90_T	117_V	1.646	1.00
127_E	174_Y	1.642	1.00
121_C	126_I	1.635	1.00
351_L	402_A	1.627	1.00
228_N	231_N	1.627	1.00
118_F	122_K	1.608	1.00
357_M	411_I	1.607	1.00
354_R	358_N	1.600	1.00
78_A	120_E	1.596	1.00
140_H	144_E	1.595	1.00
464_K	467_A	1.593	1.00
145_Y	156_F	1.591	1.00
115_R	168_F	1.589	1.00
273_T	300_K	1.587	1.00
310_Y	352_G	1.584	1.00
369_F	414_M	1.565	1.00
359_M	363_R	1.564	1.00
39_G	42_R	1.559	1.00
77_I	120_E	1.558	1.00
158_S	219_L	1.554	1.00
271_R	365_Q	1.546	1.00
17_N	63_S	1.541	1.00
153_L	156_F	1.541	1.00
73_Y	116_S	1.540	1.00
9_L	87_V	1.535	1.00
176_L	236_M	1.535	1.00
165_F	224_A	1.499	1.00
87_V	129_L	1.497	1.00
77_I	121_C	1.483	1.00
72_R	75_E	1.471	1.00
210_A	265_F	1.463	1.00
442_D	450_T	1.462	1.00
14_L	88_F	1.454	1.00
264_F	278_S	1.451	1.00
149_R	205_V	1.448	1.00
80_M	85_F	1.444	1.00
373_N	416_Y	1.428	1.00
176_L	305_F	1.424	1.00
361_Y	366_K	1.422	1.00
111_I	163_T	1.419	1.00
98_F	106_P	1.419	1.00
353_L	403_M	1.414	1.00
266_I	306_V	1.413	1.00
146_G	150_N	1.393	1.00
259_D	277_Y	1.385	1.00
29_G	101_G	1.385	1.00
418_T	438_F	1.383	1.00
90_T	130_V	1.381	1.00
82_E	459_F	1.378	1.00
223_I	226_E	1.376	1.00
170_G	228_N	1.372	1.00
100_Q	103_E	1.365	1.00
173_K	230_Q	1.359	1.00
343_D	378_K	1.350	1.00
273_T	279_A	1.340	1.00
35_M	144_E	1.339	1.00
129_L	417_T	1.338	1.00
22_A	71_H	1.328	1.00
68_D	72_R	1.312	1.00
92_I	164_C	1.310	1.00
357_M	403_M	1.310	1.00
235_C	269_Q	1.306	1.00
461_W	465_V	1.306	1.00
464_K	468_S	1.303	1.00
400_I	403_M	1.302	1.00
174_Y	232_Q	1.301	1.00
455_R	460_W	1.271	1.00
151_R	212_H	1.263	1.00
102_D	156_F	1.257	1.00
139_M	143_T	1.249	1.00
273_T	365_Q	1.240	1.00
155_E	158_S	1.230	1.00
92_I	97_L	1.227	1.00
398_E	401_R	1.227	1.00
152_K	155_E	1.220	1.00
178_F	213_Q	1.219	1.00
358_N	411_I	1.216	1.00
178_F	216_A	1.215	1.00
460_W	463_K	1.214	1.00
397_R	401_R	1.208	1.00
184_M	213_Q	1.199	1.00
78_A	82_E	1.197	1.00
111_I	167_A	1.185	1.00
202_Q	205_V	1.181	1.00
69_F	117_V	1.178	1.00
244_P	255_A	1.169	1.00
73_Y	120_E	1.166	1.00
80_M	439_V	1.166	1.00
165_F	220_A	1.164	1.00
67_T	422_I	1.161	1.00
115_R	170_G	1.159	1.00
139_M	144_E	1.152	1.00
386_E	457_K	1.151	1.00
132_L	157_F	1.150	1.00
23_F	28_K	1.146	1.00
267_D	363_R	1.145	1.00
296_D	299_L	1.144	1.00
5_P	407_I	1.141	1.00
200_E	205_V	1.139	1.00
404_G	408_A	1.139	1.00
102_D	145_Y	1.137	1.00
161_A	220_A	1.128	1.00
232_Q	367_P	1.126	1.00
148_W	153_L	1.124	1.00
361_Y	412_P	1.124	1.00
137_V	153_L	1.122	1.00
14_L	90_T	1.119	1.00
267_D	271_R	1.118	1.00
29_G	140_H	1.112	1.00
22_A	26_G	1.111	1.00
244_P	252_V	1.103	1.00
158_S	220_A	1.102	1.00
443_R	451_L	1.102	1.00
165_F	233_V	1.101	1.00
166_E	227_V	1.096	1.00
404_G	407_I	1.093	1.00
152_K	156_F	1.091	1.00
382_A	388_N	1.091	1.00
221_T	225_H	1.086	1.00
293_P	296_D	1.085	1.00
462_Y	466_I	1.085	1.00
100_Q	140_H	1.075	1.00
351_L	355_I	1.073	1.00
111_I	115_R	1.072	1.00
405_E	408_A	1.072	1.00
40_E	43_M	1.070	1.00
249_P	252_V	1.069	1.00
82_E	455_R	1.066	1.00
239_G	356_T	1.066	1.00
118_F	171_L	1.064	1.00
286_G	289_I	1.061	1.00
145_Y	152_K	1.060	1.00
242_F	258_K	1.055	1.00
115_R	122_K	1.053	1.00
245_Y	317_S	1.052	1.00
249_P	253_W	1.052	1.00
118_F	130_V	1.050	1.00
4_F	407_I	1.049	1.00
385_G	454_T	1.046	1.00
259_D	278_S	1.046	1.00
224_A	229_P	1.044	1.00
253_W	257_E	1.044	1.00
158_S	162_R	1.043	1.00
342_S	375_L	1.043	1.00
250_E	351_L	1.041	1.00
219_L	223_I	1.036	1.00
381_F	454_T	1.035	1.00
223_I	227_V	1.034	1.00
4_F	404_G	1.033	1.00
259_D	263_L	1.030	1.00
250_E	318_A	1.025	1.00
65_E	443_R	1.022	1.00
442_D	452_T	1.020	1.00
106_P	163_T	1.019	1.00
72_R	452_T	1.015	1.00
251_D	318_A	1.012	1.00
29_G	99_P	1.011	1.00
335_R	339_L	1.007	1.00
393_I	461_W	1.006	1.00
248_K	252_V	1.005	1.00
222_K	301_N	1.004	1.00
341_V	347_G	1.004	1.00
212_H	215_V	1.002	1.00
12_G	80_M	1.001	1.00
273_T	276_A	1.000	1.00
129_L	174_Y	0.995	1.00
161_A	223_I	0.994	1.00
65_E	451_L	0.991	1.00
394_S	397_R	0.990	1.00
344_W	376_G	0.989	1.00
353_L	413_L	0.989	1.00
353_L	370_L	0.983	1.00
203_D	285_K	0.981	1.00
97_L	163_T	0.980	1.00
196_F	199_G	0.974	1.00
156_F	159_R	0.970	0.99
164_C	168_F	0.969	0.99
163_T	167_A	0.966	0.99
129_L	369_F	0.965	0.99
7_S	414_M	0.965	0.99
19_S	69_F	0.963	0.99
137_V	147_S	0.962	0.99
86_K	469_N	0.961	0.99
169_D	231_N	0.961	0.99
340_Q	391_Y	0.959	0.99
340_Q	398_E	0.957	0.99
221_T	233_V	0.948	0.99
234_G	307_S	0.945	0.99
28_K	95_S	0.944	0.99
146_G	149_R	0.942	0.99
9_L	129_L	0.942	0.99
258_K	316_A	0.940	0.99
252_V	255_A	0.940	0.99
165_F	231_N	0.938	0.99
378_K	433_S	0.938	0.99
435_R	443_R	0.936	0.99
256_L	259_D	0.934	0.99
377_A	391_Y	0.933	0.99
270_A	366_K	0.926	0.99
116_S	119_E	0.924	0.99
242_F	255_A	0.917	0.99
154_V	219_L	0.914	0.99
422_I	441_V	0.913	0.99
185_L	209_A	0.908	0.99
103_E	140_H	0.900	0.99
247_C	252_V	0.899	0.99
340_Q	394_S	0.896	0.99
253_W	256_L	0.895	0.99
465_V	469_N	0.894	0.99
381_F	385_G	0.894	0.99
75_E	78_A	0.891	0.99
111_I	164_C	0.888	0.99
344_W	434_K	0.888	0.99
112_A	115_R	0.886	0.99
98_F	103_E	0.884	0.99
234_G	305_F	0.884	0.99
161_A	165_F	0.883	0.99
61_Y	433_S	0.878	0.99
115_R	118_F	0.877	0.99
78_A	81_A	0.876	0.99
361_Y	365_Q	0.876	0.99
375_L	391_Y	0.876	0.99
145_Y	153_L	0.875	0.99
222_K	298_I	0.871	0.99
133_C	137_V	0.868	0.99
167_A	171_L	0.867	0.99
220_A	223_I	0.867	0.99
353_L	402_A	0.865	0.99
85_F	421_C	0.865	0.99
44_A	57_D	0.863	0.99
376_G	434_K	0.862	0.99
100_Q	105_T	0.861	0.99
113_F	117_V	0.860	0.99
122_K	128_P	0.858	0.99
335_R	341_V	0.856	0.99
407_I	413_L	0.855	0.99
256_L	277_Y	0.855	0.99
267_D	364_Y	0.850	0.99
27_D	107_N	0.850	0.99
80_M	126_I	0.849	0.99
351_L	405_E	0.848	0.99
381_F	386_E	0.846	0.99
160_Y	164_C	0.846	0.99
149_R	200_E	0.843	0.99
176_L	307_S	0.840	0.99
3_V	6_E	0.838	0.99
237_L	266_I	0.838	0.99
154_V	215_V	0.837	0.99
460_W	464_K	0.832	0.98
387_I	454_T	0.830	0.98
133_C	136_D	0.828	0.98
170_G	231_N	0.824	0.98
224_A	228_N	0.820	0.98
313_S	347_G	0.820	0.98
290_N	294_G	0.819	0.98
82_E	463_K	0.814	0.98
169_D	228_N	0.813	0.98
219_L	222_K	0.813	0.98
349_D	352_G	0.812	0.98
280_R	283_R	0.810	0.98
178_F	184_M	0.809	0.98
245_Y	251_D	0.807	0.98
102_D	144_E	0.805	0.98
390_D	394_S	0.804	0.98
401_R	405_E	0.802	0.98
308_F	368_L	0.802	0.98
32_T	137_V	0.801	0.98
217_S	221_T	0.801	0.98
97_L	164_C	0.801	0.98
382_A	385_G	0.801	0.98
16_A	93_A	0.798	0.98
177_T	235_C	0.797	0.98
312_A	347_G	0.796	0.98
151_R	294_G	0.794	0.98
239_G	308_F	0.790	0.98
263_L	363_R	0.788	0.98
313_S	349_D	0.788	0.98
198_E	201_N	0.787	0.98
10_W	400_I	0.786	0.98
276_A	279_A	0.785	0.98
294_G	298_I	0.784	0.98
102_D	140_H	0.783	0.98
19_S	67_T	0.781	0.98
358_N	362_D	0.780	0.98
73_Y	77_I	0.779	0.98
248_K	251_D	0.775	0.98
281_V	285_K	0.773	0.97
85_F	462_Y	0.773	0.97
7_S	469_N	0.773	0.97
5_P	412_P	0.773	0.97
204_Q	208_Q	0.773	0.97
28_K	31_T	0.772	0.97
101_G	140_H	0.772	0.97
177_T	217_S	0.771	0.97
457_K	460_W	0.771	0.97
183_I	238_A	0.769	0.97
354_R	402_A	0.768	0.97
108_Q	115_R	0.767	0.97
106_P	111_I	0.763	0.97
313_S	352_G	0.763	0.97
143_T	189_F	0.762	0.97
128_P	173_K	0.761	0.97
9_L	127_E	0.759	0.97
65_E	68_D	0.755	0.97
102_D	159_R	0.753	0.97
83_M	455_R	0.753	0.97
157_F	161_A	0.752	0.97
81_A	125_G	0.752	0.97
150_N	156_F	0.751	0.97
163_T	166_E	0.751	0.97
357_M	413_L	0.745	0.97
24_R	30_L	0.744	0.97
76_D	453_R	0.740	0.97
361_Y	411_I	0.740	0.97
242_F	316_A	0.735	0.97
93_A	136_D	0.734	0.97
270_A	303_V	0.729	0.96
197_E	200_E	0.728	0.96
439_V	455_R	0.726	0.96
348_I	377_A	0.725	0.96
169_D	227_V	0.720	0.96
110_G	113_F	0.719	0.96
23_F	64_H	0.719	0.96
287_V	290_N	0.718	0.96
336_N	339_L	0.718	0.96
368_L	411_I	0.718	0.96
406_A	411_I	0.717	0.96
177_T	233_V	0.715	0.96
270_A	306_V	0.714	0.96
130_V	172_V	0.714	0.96
208_Q	290_N	0.712	0.96
358_N	361_Y	0.712	0.96
122_K	173_K	0.712	0.96
212_H	290_N	0.710	0.96
182_N	238_A	0.707	0.96
280_R	284_E	0.706	0.96
253_W	351_L	0.706	0.96
256_L	359_M	0.704	0.96
214_L	299_L	0.704	0.96
366_K	412_P	0.703	0.96
10_W	86_K	0.703	0.96
424_L	436_Y	0.702	0.96
149_R	209_A	0.701	0.96
165_F	227_V	0.701	0.96
3_V	404_G	0.700	0.96
210_A	264_F	0.698	0.95
72_R	451_L	0.698	0.95
214_L	269_Q	0.695	0.95
22_A	70_Y	0.695	0.95
183_I	187_S	0.693	0.95
26_G	70_Y	0.689	0.95
293_P	297_E	0.689	0.95
236_M	309_S	0.687	0.95
241_N	355_I	0.686	0.95
438_F	462_Y	0.685	0.95
162_R	226_E	0.682	0.95
122_K	127_E	0.679	0.95
14_L	422_I	0.679	0.95
382_A	454_T	0.677	0.95
63_S	66_A	0.677	0.95
23_F	93_A	0.677	0.95
273_T	296_D	0.674	0.95
195_V	198_E	0.674	0.95
30_L	38_H	0.673	0.94
400_I	418_T	0.673	0.94
252_V	256_L	0.673	0.94
357_M	406_A	0.671	0.94
351_L	354_R	0.671	0.94
155_E	159_R	0.671	0.94
286_G	290_N	0.669	0.94
343_D	377_A	0.666	0.94
216_A	220_A	0.664	0.94
426_S	436_Y	0.664	0.94
393_I	457_K	0.661	0.94
57_D	433_S	0.659	0.94
207_Y	282_F	0.659	0.94
309_S	371_V	0.659	0.94
239_G	266_I	0.658	0.94
19_S	424_L	0.657	0.94
272_G	300_K	0.656	0.94
77_I	126_I	0.656	0.94
83_M	438_F	0.654	0.94
166_E	223_I	0.654	0.94
74_K	78_A	0.653	0.94
197_E	201_N	0.653	0.94
278_S	282_F	0.653	0.94
237_L	265_F	0.652	0.93
90_T	121_C	0.652	0.93
121_C	124_Y	0.651	0.93
164_C	175_W	0.651	0.93
306_V	366_K	0.650	0.93
100_Q	144_E	0.648	0.93
121_C	125_G	0.648	0.93
118_F	172_V	0.646	0.93
310_Y	353_L	0.644	0.93
151_R	215_V	0.644	0.93
308_F	360_M	0.643	0.93
386_E	454_T	0.642	0.93
157_F	178_F	0.641	0.93
367_P	412_P	0.641	0.93
400_I	465_V	0.641	0.93
30_L	139_M	0.638	0.93
317_S	332_K	0.637	0.93
98_F	105_T	0.637	0.93
129_L	176_L	0.636	0.93
89_R	179_N	0.634	0.93
243_Y	313_S	0.634	0.93
382_A	387_I	0.634	0.93
44_A	61_Y	0.633	0.92
405_E	409_D	0.633	0.92
367_P	414_M	0.633	0.92
248_K	318_A	0.631	0.92
119_E	170_G	0.631	0.92
63_S	430_G	0.630	0.92
201_N	204_Q	0.629	0.92
13_A	417_T	0.626	0.92
86_K	127_E	0.623	0.92
98_F	102_D	0.623	0.92
141_L	156_F	0.622	0.92
11_G	417_T	0.621	0.92
218_A	299_L	0.620	0.92
440_F	456_K	0.618	0.92
41_H	44_A	0.617	0.91
390_D	393_I	0.617	0.91
111_I	168_F	0.617	0.91
259_D	359_M	0.616	0.91
98_F	159_R	0.616	0.91
161_A	164_C	0.615	0.91
465_V	468_S	0.614	0.91
172_V	175_W	0.613	0.91
92_I	118_F	0.613	0.91
296_D	300_K	0.611	0.91
218_A	302_T	0.610	0.91
80_M	421_C	0.610	0.91
263_L	359_M	0.609	0.91
386_E	460_W	0.609	0.91
221_T	303_V	0.609	0.91
7_S	407_I	0.609	0.91
9_L	86_K	0.608	0.91
319_E	322_A	0.607	0.91
369_F	415_G	0.606	0.91
245_Y	315_C	0.606	0.91
254_A	258_K	0.605	0.91
86_K	466_I	0.605	0.91
344_W	429_T	0.604	0.91
149_R	208_Q	0.604	0.91
101_G	141_L	0.604	0.91
425_V	443_R	0.603	0.91
232_Q	414_M	0.603	0.91
218_A	301_N	0.602	0.90
381_F	384_N	0.602	0.90
246_S	317_S	0.598	0.90
239_G	262_N	0.598	0.90
451_L	455_R	0.597	0.90
222_K	302_T	0.597	0.90
264_F	282_F	0.595	0.90
4_F	469_N	0.595	0.90
280_R	405_E	0.594	0.90
133_C	184_M	0.594	0.90
122_K	125_G	0.592	0.90
116_S	120_E	0.592	0.90
159_R	163_T	0.591	0.90
132_L	165_F	0.591	0.90
440_F	452_T	0.591	0.90
403_M	407_I	0.591	0.90
298_I	301_N	0.591	0.90
424_L	427_A	0.591	0.90
154_V	216_A	0.591	0.90
207_Y	285_K	0.590	0.90
14_L	421_C	0.590	0.90
234_G	369_F	0.588	0.89
174_Y	369_F	0.588	0.89
278_S	281_V	0.585	0.89
37_P	425_V	0.583	0.89
66_A	451_L	0.583	0.89
97_L	111_I	0.580	0.89
100_Q	156_F	0.578	0.89
204_Q	289_I	0.577	0.89
30_L	95_S	0.577	0.89
83_M	459_F	0.576	0.88
283_R	288_T	0.574	0.88
343_D	434_K	0.574	0.88
79_L	422_I	0.573	0.88
81_A	123_K	0.573	0.88
227_V	231_N	0.573	0.88
74_K	77_I	0.570	0.88
239_G	360_M	0.570	0.88
240_G	314_R	0.570	0.88
32_T	143_T	0.569	0.88
79_L	439_V	0.569	0.88
421_C	439_V	0.569	0.88
154_V	158_S	0.569	0.88
266_I	360_M	0.568	0.88
335_R	338_Y	0.567	0.88
140_H	156_F	0.566	0.88
217_S	269_Q	0.565	0.88
208_Q	212_H	0.564	0.87
32_T	133_C	0.564	0.87
222_K	225_H	0.563	0.87
385_G	452_T	0.562	0.87
368_L	413_L	0.561	0.87
4_F	10_W	0.561	0.87
88_F	121_C	0.560	0.87
24_R	64_H	0.558	0.87
290_N	295_D	0.555	0.87
180_E	311_Y	0.555	0.87
204_Q	288_T	0.554	0.87
435_R	440_F	0.553	0.86
257_E	318_A	0.553	0.86
360_M	368_L	0.551	0.86
26_G	107_N	0.551	0.86
119_E	123_K	0.551	0.86
37_P	63_S	0.551	0.86
258_K	261_E	0.550	0.86
85_F	126_I	0.550	0.86
103_E	159_R	0.550	0.86
263_L	267_D	0.550	0.86
65_E	71_H	0.550	0.86
342_S	376_G	0.549	0.86
140_H	143_T	0.549	0.86
22_A	28_K	0.548	0.86
69_F	80_M	0.547	0.86
375_L	379_D	0.544	0.86
420_G	424_L	0.544	0.86
243_Y	349_D	0.544	0.86
311_Y	372_E	0.543	0.85
369_F	417_T	0.543	0.85
425_V	432_M	0.542	0.85
19_S	88_F	0.542	0.85
244_P	251_D	0.542	0.85
7_S	86_K	0.541	0.85
317_S	334_L	0.540	0.85
396_L	400_I	0.540	0.85
84_G	463_K	0.539	0.85
342_S	377_A	0.538	0.85
132_L	161_A	0.538	0.85
393_I	397_R	0.537	0.85
129_L	414_M	0.534	0.84
43_M	61_Y	0.533	0.84
23_F	38_H	0.531	0.84
72_R	450_T	0.530	0.84
35_M	39_G	0.529	0.84
212_H	294_G	0.528	0.84
44_A	429_T	0.527	0.84
17_N	37_P	0.527	0.84
189_F	200_E	0.526	0.84
355_I	358_N	0.525	0.83
33_V	36_I	0.525	0.83
371_V	414_M	0.524	0.83
444_D	452_T	0.523	0.83
307_S	371_V	0.523	0.83
279_A	296_D	0.523	0.83
80_M	88_F	0.522	0.83
33_V	427_A	0.521	0.83
221_T	301_N	0.520	0.83
341_V	345_G	0.520	0.83
148_W	178_F	0.519	0.83
266_I	270_A	0.519	0.83
69_F	77_I	0.517	0.83
260_R	278_S	0.516	0.82
44_A	433_S	0.516	0.82
339_L	347_G	0.515	0.82
69_F	73_Y	0.515	0.82
221_T	224_A	0.514	0.82
131_T	236_M	0.514	0.82
14_L	69_F	0.514	0.82
201_N	206_K	0.514	0.82
221_T	302_T	0.511	0.82
387_I	440_F	0.510	0.82
14_L	424_L	0.509	0.82
236_M	305_F	0.509	0.82
29_G	98_F	0.509	0.82
140_H	145_Y	0.509	0.82
439_V	459_F	0.508	0.81
177_T	220_A	0.508	0.81
141_L	153_L	0.508	0.81
145_Y	150_N	0.508	0.81
215_V	298_I	0.508	0.81
143_T	200_E	0.507	0.81
251_D	254_A	0.506	0.81
199_G	202_Q	0.506	0.81
419_W	424_L	0.506	0.81
28_K	136_D	0.505	0.81
198_E	202_Q	0.504	0.81
189_F	209_A	0.503	0.81
169_D	229_P	0.502	0.81
357_M	368_L	0.502	0.81
108_Q	111_I	0.502	0.81
23_F	65_E	0.501	0.81
122_K	170_G	0.500	0.80
19_S	113_F	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1v02A	2	0.9367	100	0.118	Contact Map
2dgaA	5	0.943	100	0.122	Contact Map
3ptmA	1	0.9388	100	0.122	Contact Map
2jf7A	5	0.9262	100	0.124	Contact Map
1v08A	2	0.9388	100	0.124	Contact Map
3wq5A	1	0.9388	100	0.125	Contact Map
1cbgA	2	0.9388	100	0.128	Contact Map
4iplA	2	0.9536	100	0.131	Contact Map
4f66A	2	0.9747	100	0.131	Contact Map
3w53A	1	0.9346	100	0.133	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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