RECG - ECOLI - GREMLIN Contacts

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RECG - ATP-dependent DNA helicase RecG

UniProt:	P24230	Sequences: MKGRLLDAVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRYEDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFSAAMKNSLAAGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQHPAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDTLKNKLLAALPFKPTGAQARVVAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHANNFRNWFAPLGIEVGWLAGKQKGKARLAQQEAIASGQVQMIVGTHAIFQEQVQFNGLALVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRTDIIDRVHHACITEGRQAYWVCTLIEESELLEAQAAEATWEELKLALPELNVGLVHGRMKPAEKQAVMASFKQGELHLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIERWMPETERYSNA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10829
Length:	693 (625)
Sequences:	6284 (4714)
Seq/√Len:	188.6

ECOLI - RECG DEAD MFD RECQ YFJK RAPA YEJH RHLE
BACSU - RECG MFD YWQA RECQ YPRA CSHA DBPA COMFA
HALSA - RAD25 Q9HNB2 Q9HN80 O52003 HELS
SULSO - Q981C8 HELX Q97X74 Q97ZF9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
538_S	543_E	6.150	1.00
310_A	320_V	6.076	1.00
625_K	628_E	5.599	1.00
226_L	664_L	5.333	1.00
357_G	361_L	4.760	1.00
484_R	590_V	4.321	1.00
485_Q	561_N	4.303	1.00
366_A	371_Q	4.088	1.00
519_N	545_H	3.986	1.00
349_G	372_V	3.898	1.00
272_A	449_D	3.607	1.00
271_G	450_E	3.574	1.00
521_G	544_L	3.536	1.00
275_R	449_D	3.460	1.00
26_A	31_H	3.344	1.00
534_A	538_S	3.292	1.00
314_I	374_M	3.288	1.00
368_A	387_Q	3.267	1.00
193_T	196_E	3.227	1.00
314_I	320_V	3.169	1.00
542_G	545_H	3.154	1.00
616_S	621_V	3.148	1.00
367_I	372_V	3.037	1.00
480_I	518_L	3.000	1.00
66_G	85_I	2.979	1.00
489_V	553_I	2.951	1.00
535_V	544_L	2.866	1.00
307_A	337_F	2.859	1.00
277_V	308_L	2.854	1.00
347_E	373_Q	2.823	1.00
281_E	312_R	2.808	1.00
268_K	274_A	2.794	1.00
337_F	376_V	2.744	1.00
456_T	591_A	2.723	1.00
321_A	381_I	2.673	1.00
479_C	482_E	2.607	1.00
365_E	369_S	2.601	1.00
515_L	546_L	2.590	1.00
355_Q	363_Q	2.586	1.00
362_A	366_A	2.578	1.00
621_V	625_K	2.532	1.00
269_P	304_L	2.524	1.00
349_G	363_Q	2.513	1.00
334_A	338_R	2.489	1.00
410_L	413_K	2.436	1.00
318_K	390_G	2.368	1.00
65_E	112_R	2.368	1.00
537_A	541_Q	2.351	1.00
621_V	624_Q	2.326	1.00
367_I	375_I	2.311	1.00
521_G	538_S	2.288	1.00
310_A	395_I	2.287	1.00
322_L	337_F	2.251	1.00
358_K	361_L	2.241	1.00
349_G	366_A	2.235	1.00
356_K	359_A	2.216	1.00
611_Q	615_D	2.174	1.00
459_T	591_A	2.163	1.00
347_E	366_A	2.150	1.00
661_V	665_A	2.139	1.00
475_V	486_A	2.132	1.00
56_L	62_A	2.128	1.00
613_L	616_S	2.127	1.00
309_A	393_L	2.124	1.00
490_C	507_T	2.122	1.00
339_N	558_D	2.099	1.00
476_H	517_E	2.096	1.00
336_N	558_D	2.054	1.00
361_L	365_E	2.046	1.00
508_W	512_K	2.031	1.00
484_R	563_S	2.026	1.00
508_W	522_L	1.964	1.00
592_S	596_L	1.918	1.00
509_E	513_L	1.914	1.00
612_V	625_K	1.903	1.00
284_M	313_A	1.889	1.00
363_Q	372_V	1.881	1.00
229_L	649_A	1.867	1.00
181_E	188_S	1.863	1.00
200_T	209_Q	1.841	1.00
528_K	531_E	1.837	1.00
372_V	375_I	1.809	1.00
272_A	275_R	1.809	1.00
283_D	292_R	1.801	1.00
479_C	484_R	1.799	1.00
667_H	671_R	1.754	1.00
52_P	55_E	1.748	1.00
473_D	477_H	1.735	1.00
521_G	535_V	1.728	1.00
366_A	372_V	1.710	1.00
310_A	374_M	1.708	1.00
248_A	251_L	1.700	1.00
474_R	477_H	1.698	1.00
456_T	589_A	1.678	1.00
195_P	199_R	1.665	1.00
347_E	371_Q	1.659	1.00
346_I	373_Q	1.658	1.00
160_Q	164_R	1.649	1.00
349_G	375_I	1.648	1.00
633_G	637_G	1.643	1.00
206_P	209_Q	1.641	1.00
475_V	566_I	1.627	1.00
460_T	596_L	1.619	1.00
67_E	112_R	1.615	1.00
75_F	78_R	1.607	1.00
362_A	365_E	1.598	1.00
540_K	558_D	1.595	1.00
94_M	115_A	1.594	1.00
85_I	115_A	1.590	1.00
624_Q	628_E	1.583	1.00
660_E	663_R	1.575	1.00
154_T	163_L	1.567	1.00
612_V	622_I	1.563	1.00
255_D	315_A	1.561	1.00
280_I	294_V	1.557	1.00
248_A	422_H	1.555	1.00
276_V	279_E	1.538	1.00
42_L	153_P	1.533	1.00
87_D	90_G	1.527	1.00
307_A	341_F	1.517	1.00
221_Q	225_I	1.514	1.00
622_I	625_K	1.509	1.00
533_Q	537_A	1.504	1.00
518_L	545_H	1.500	1.00
75_F	79_R	1.500	1.00
154_T	160_Q	1.498	1.00
596_L	599_K	1.489	1.00
462_A	610_L	1.486	1.00
615_D	621_V	1.485	1.00
337_F	348_V	1.468	1.00
360_R	364_Q	1.465	1.00
471_I	566_I	1.451	1.00
598_Y	601_P	1.449	1.00
320_V	395_I	1.445	1.00
311_L	315_A	1.441	1.00
230_L	668_I	1.430	1.00
592_S	598_Y	1.429	1.00
592_S	599_K	1.427	1.00
159_K	162_T	1.427	1.00
108_A	111_R	1.425	1.00
659_P	663_R	1.423	1.00
225_I	657_M	1.422	1.00
272_A	450_E	1.420	1.00
237_L	666_R	1.417	1.00
472_I	476_H	1.412	1.00
476_H	481_T	1.410	1.00
606_A	616_S	1.409	1.00
467_R	470_D	1.407	1.00
590_V	596_L	1.407	1.00
185_P	188_S	1.401	1.00
650_D	653_R	1.399	1.00
565_M	585_V	1.390	1.00
63_T	116_Y	1.387	1.00
85_I	92_L	1.387	1.00
511_L	520_V	1.381	1.00
230_L	234_L	1.379	1.00
663_R	667_H	1.378	1.00
611_Q	614_R	1.374	1.00
632_P	635_L	1.374	1.00
666_R	670_E	1.372	1.00
523_V	549_A	1.370	1.00
163_L	167_T	1.368	1.00
661_V	664_L	1.364	1.00
603_S	606_A	1.363	1.00
292_R	446_S	1.355	1.00
662_Q	666_R	1.344	1.00
66_G	115_A	1.343	1.00
634_E	639_R	1.337	1.00
197_A	201_L	1.334	1.00
443_L	446_S	1.333	1.00
244_Q	288_V	1.327	1.00
507_T	568_E	1.326	1.00
92_L	128_M	1.326	1.00
523_V	527_M	1.319	1.00
259_N	263_A	1.319	1.00
169_Q	172_D	1.309	1.00
355_Q	360_R	1.295	1.00
45_E	61_Y	1.294	1.00
122_G	125_G	1.291	1.00
492_L	496_S	1.283	1.00
38_L	194_L	1.280	1.00
620_F	623_A	1.279	1.00
95_R	127_E	1.279	1.00
534_A	537_A	1.278	1.00
34_Q	38_L	1.277	1.00
262_L	308_L	1.274	1.00
277_V	305_V	1.266	1.00
659_P	662_Q	1.265	1.00
606_A	609_R	1.262	1.00
284_M	422_H	1.255	1.00
205_P	209_Q	1.254	1.00
275_R	279_E	1.252	1.00
323_M	382_F	1.250	1.00
364_Q	385_Q	1.247	1.00
623_A	627_L	1.245	1.00
196_E	200_T	1.244	1.00
563_S	590_V	1.240	1.00
64_V	92_L	1.228	1.00
314_I	346_I	1.215	1.00
252_S	316_H	1.215	1.00
620_F	624_Q	1.214	1.00
83_C	107_L	1.213	1.00
364_Q	386_V	1.213	1.00
355_Q	359_A	1.209	1.00
480_I	546_L	1.206	1.00
93_T	125_G	1.196	1.00
168_D	172_D	1.196	1.00
200_T	205_P	1.192	1.00
262_L	274_A	1.181	1.00
432_P	437_M	1.178	1.00
431_I	434_T	1.174	1.00
192_M	196_E	1.173	1.00
294_V	426_M	1.172	1.00
363_Q	367_I	1.170	1.00
57_L	60_V	1.169	1.00
468_R	568_E	1.168	1.00
331_E	335_N	1.167	1.00
607_Q	611_Q	1.167	1.00
279_E	294_V	1.166	1.00
167_T	170_A	1.162	1.00
649_A	658_I	1.161	1.00
662_Q	665_A	1.159	1.00
509_E	512_K	1.158	1.00
251_L	313_A	1.151	1.00
453_P	456_T	1.148	1.00
443_L	448_I	1.144	1.00
276_V	294_V	1.142	1.00
277_V	281_E	1.135	1.00
154_T	157_G	1.134	1.00
83_C	96_F	1.134	1.00
366_A	369_S	1.132	1.00
67_E	86_S	1.127	1.00
185_P	189_Q	1.123	1.00
506_A	509_E	1.123	1.00
590_V	598_Y	1.122	1.00
408_L	411_W	1.118	1.00
284_M	312_R	1.114	1.00
626_D	631_G	1.109	1.00
358_K	362_A	1.105	1.00
323_M	381_I	1.096	1.00
31_H	35_D	1.093	1.00
596_L	601_P	1.092	1.00
612_V	616_S	1.087	1.00
604_K	616_S	1.085	1.00
188_S	193_T	1.079	1.00
294_V	448_I	1.079	1.00
68_V	83_C	1.075	1.00
82_T	93_T	1.072	1.00
119_A	128_M	1.070	1.00
65_E	114_L	1.070	1.00
318_K	392_A	1.070	1.00
458_V	592_S	1.066	1.00
471_I	474_R	1.062	1.00
335_N	558_D	1.054	1.00
28_I	155_T	1.052	1.00
70_N	84_Q	1.046	1.00
463_I	471_I	1.046	1.00
471_I	476_H	1.046	1.00
66_G	92_L	1.045	1.00
619_G	627_L	1.045	1.00
519_N	543_E	1.044	1.00
310_A	322_L	1.043	1.00
96_F	99_F	1.042	1.00
445_T	448_I	1.041	1.00
232_H	646_F	1.040	1.00
257_L	311_L	1.038	1.00
668_I	671_R	1.038	1.00
473_D	476_H	1.037	1.00
592_S	597_L	1.035	1.00
494_E	526_R	1.031	1.00
94_M	128_M	1.028	1.00
507_T	510_E	1.026	1.00
165_K	168_D	1.023	1.00
224_L	227_E	1.020	1.00
606_A	610_L	1.019	1.00
74_S	77_G	1.019	1.00
53_I	56_L	1.018	1.00
128_M	131_P	1.018	1.00
433_R	437_M	1.015	1.00
465_D	599_K	1.014	1.00
622_I	627_L	1.010	1.00
168_D	203_R	1.008	1.00
625_K	629_I	1.005	1.00
219_P	222_R	1.004	0.99
255_D	259_N	1.002	0.99
646_F	649_A	1.002	0.99
121_R	124_Y	0.998	0.99
508_W	520_V	0.997	0.99
564_L	595_V	0.994	0.99
656_A	659_P	0.992	0.99
258_K	281_E	0.988	0.99
169_Q	173_L	0.985	0.99
567_I	596_L	0.984	0.99
363_Q	366_A	0.981	0.99
171_L	174_L	0.981	0.99
668_I	672_Y	0.981	0.99
162_T	166_L	0.977	0.99
452_P	457_P	0.977	0.99
476_H	514_A	0.976	0.99
164_R	167_T	0.974	0.99
261_L	308_L	0.972	0.99
224_L	648_V	0.972	0.99
74_S	78_R	0.972	0.99
294_V	424_L	0.971	0.99
442_D	448_I	0.971	0.99
258_K	261_L	0.970	0.99
163_L	166_L	0.966	0.99
99_F	130_H	0.965	0.99
285_A	312_R	0.963	0.99
181_E	223_R	0.962	0.99
194_L	197_A	0.962	0.99
519_N	544_L	0.962	0.99
592_S	595_V	0.958	0.99
290_M	424_L	0.958	0.99
623_A	626_D	0.957	0.99
310_A	337_F	0.956	0.99
279_E	283_D	0.953	0.99
249_Q	318_K	0.950	0.99
484_R	561_N	0.950	0.99
121_R	126_A	0.949	0.99
456_T	459_T	0.946	0.99
338_R	342_A	0.946	0.99
223_R	227_E	0.943	0.99
184_P	187_L	0.932	0.99
461_V	470_D	0.929	0.99
530_A	534_A	0.926	0.99
660_E	664_L	0.925	0.99
475_V	480_I	0.923	0.99
592_S	601_P	0.922	0.99
160_Q	163_L	0.921	0.99
337_F	374_M	0.920	0.99
321_A	391_L	0.918	0.99
608_I	611_Q	0.917	0.99
304_L	340_W	0.916	0.99
257_L	260_K	0.914	0.99
520_V	548_V	0.914	0.99
52_P	88_G	0.913	0.99
200_T	208_L	0.913	0.99
463_I	467_R	0.912	0.99
182_L	188_S	0.910	0.99
166_L	169_Q	0.910	0.99
192_M	197_A	0.909	0.99
336_N	339_N	0.908	0.99
226_L	230_L	0.908	0.99
627_L	630_R	0.908	0.99
307_A	374_M	0.907	0.99
626_D	630_R	0.907	0.99
251_L	422_H	0.906	0.99
312_R	316_H	0.906	0.99
470_D	474_R	0.903	0.99
237_L	669_H	0.901	0.99
664_L	667_H	0.901	0.99
342_A	345_G	0.900	0.99
604_K	607_Q	0.900	0.99
156_E	159_K	0.900	0.99
178_A	195_P	0.899	0.99
327_E	354_K	0.899	0.99
86_S	91_I	0.899	0.99
184_P	188_S	0.896	0.99
484_R	589_A	0.890	0.99
103_M	106_S	0.888	0.99
84_Q	93_T	0.888	0.99
260_K	264_A	0.885	0.99
628_E	631_G	0.885	0.99
411_W	414_G	0.884	0.99
30_L	36_L	0.881	0.99
322_L	376_V	0.880	0.99
52_P	89_S	0.879	0.99
551_T	581_L	0.879	0.99
590_V	599_K	0.877	0.99
596_L	600_T	0.877	0.99
375_I	388_F	0.876	0.99
493_I	526_R	0.875	0.99
257_L	315_A	0.875	0.99
339_N	343_P	0.872	0.99
194_L	227_E	0.870	0.99
483_G	486_A	0.866	0.99
69_L	86_S	0.863	0.98
608_I	625_K	0.863	0.98
280_I	309_A	0.860	0.98
619_G	624_Q	0.859	0.98
179_I	198_L	0.858	0.98
370_G	389_N	0.858	0.98
69_L	91_I	0.856	0.98
590_V	600_T	0.856	0.98
605_T	608_I	0.855	0.98
152_Y	155_T	0.854	0.98
606_A	613_L	0.853	0.98
151_V	155_T	0.852	0.98
610_L	613_L	0.847	0.98
409_A	413_K	0.846	0.98
207_T	210_L	0.846	0.98
201_L	204_P	0.845	0.98
452_P	455_R	0.843	0.98
508_W	548_V	0.842	0.98
99_F	102_A	0.841	0.98
666_R	669_H	0.837	0.98
144_L	147_T	0.837	0.98
194_L	198_L	0.837	0.98
279_E	292_R	0.836	0.98
613_L	617_N	0.832	0.98
197_A	202_H	0.832	0.98
654_D	658_I	0.832	0.98
619_G	622_I	0.832	0.98
359_A	362_A	0.831	0.98
620_F	630_R	0.828	0.98
155_T	158_V	0.828	0.98
222_R	656_A	0.827	0.98
283_D	446_S	0.827	0.98
658_I	662_Q	0.827	0.98
519_N	542_G	0.826	0.98
283_D	290_M	0.825	0.98
307_A	340_W	0.823	0.98
461_V	595_V	0.821	0.98
40_L	201_L	0.820	0.98
637_G	640_Q	0.820	0.98
620_F	625_K	0.820	0.98
451_L	617_N	0.819	0.98
604_K	608_I	0.818	0.98
506_A	510_E	0.818	0.98
117_G	122_G	0.818	0.98
452_P	456_T	0.814	0.98
637_G	641_T	0.814	0.98
274_A	278_A	0.812	0.98
475_V	515_L	0.812	0.98
384_E	409_A	0.810	0.98
276_V	446_S	0.810	0.98
247_H	251_L	0.809	0.98
487_Y	559_V	0.807	0.98
86_S	89_S	0.807	0.98
261_L	311_L	0.806	0.98
166_L	170_A	0.806	0.98
655_Q	659_P	0.803	0.98
167_T	171_L	0.803	0.98
74_S	80_M	0.803	0.98
51_Y	60_V	0.801	0.98
58_P	121_R	0.800	0.98
26_A	29_N	0.797	0.97
434_T	437_M	0.797	0.97
314_I	373_Q	0.796	0.97
568_E	597_L	0.795	0.97
168_D	173_L	0.794	0.97
218_H	221_Q	0.792	0.97
231_A	234_L	0.792	0.97
665_A	668_I	0.792	0.97
49_H	55_E	0.791	0.97
637_G	642_G	0.790	0.97
28_I	39_H	0.790	0.97
198_L	202_H	0.790	0.97
518_L	546_L	0.789	0.97
488_W	568_E	0.786	0.97
620_F	627_L	0.786	0.97
51_Y	55_E	0.785	0.97
30_L	35_D	0.783	0.97
620_F	626_D	0.783	0.97
272_A	447_V	0.780	0.97
353_G	358_K	0.780	0.97
276_V	305_V	0.779	0.97
624_Q	631_G	0.778	0.97
170_A	173_L	0.778	0.97
99_F	103_M	0.778	0.97
634_E	637_G	0.777	0.97
475_V	564_L	0.776	0.97
624_Q	655_Q	0.776	0.97
30_L	39_H	0.776	0.97
51_Y	56_L	0.775	0.97
251_L	312_R	0.774	0.97
471_I	595_V	0.774	0.97
329_L	332_Q	0.772	0.97
608_I	628_E	0.772	0.97
86_S	90_G	0.771	0.97
477_H	482_E	0.771	0.97
477_H	481_T	0.770	0.97
38_L	198_L	0.767	0.97
481_T	517_E	0.767	0.97
271_G	274_A	0.767	0.97
225_I	648_V	0.766	0.97
122_G	126_A	0.766	0.97
167_T	172_D	0.763	0.97
470_D	473_D	0.763	0.97
505_E	522_L	0.762	0.97
623_A	630_R	0.759	0.97
154_T	159_K	0.758	0.97
452_P	459_T	0.757	0.97
102_A	106_S	0.755	0.96
264_A	343_P	0.754	0.96
76_G	79_R	0.752	0.96
365_E	368_A	0.751	0.96
170_A	174_L	0.751	0.96
150_P	153_P	0.750	0.96
73_I	81_M	0.749	0.96
321_A	388_F	0.749	0.96
251_L	284_M	0.747	0.96
133_Y	136_Q	0.744	0.96
665_A	669_H	0.744	0.96
260_K	263_A	0.744	0.96
563_S	589_A	0.742	0.96
390_G	419_F	0.742	0.96
660_E	668_I	0.741	0.96
661_V	672_Y	0.740	0.96
346_I	374_M	0.739	0.96
127_E	130_H	0.739	0.96
656_A	660_E	0.738	0.96
375_I	381_I	0.736	0.96
39_H	153_P	0.735	0.96
630_R	633_G	0.734	0.96
190_G	193_T	0.734	0.96
619_G	623_A	0.732	0.96
158_V	162_T	0.731	0.96
58_P	62_A	0.729	0.96
72_N	84_Q	0.727	0.96
339_N	342_A	0.725	0.96
45_E	48_T	0.724	0.96
68_V	107_L	0.723	0.95
624_Q	627_L	0.723	0.95
98_N	103_M	0.721	0.95
248_A	252_S	0.720	0.95
104_K	111_R	0.718	0.95
182_L	187_L	0.717	0.95
486_A	546_L	0.717	0.95
591_A	596_L	0.717	0.95
442_D	445_T	0.716	0.95
53_I	66_G	0.715	0.95
126_A	129_I	0.715	0.95
53_I	89_S	0.713	0.95
476_H	518_L	0.713	0.95
623_A	631_G	0.711	0.95
84_Q	91_I	0.708	0.95
659_P	668_I	0.708	0.95
632_P	637_G	0.708	0.95
479_C	564_L	0.708	0.95
627_L	632_P	0.707	0.95
658_I	664_L	0.707	0.95
664_L	668_I	0.707	0.95
250_P	287_D	0.705	0.95
365_E	371_Q	0.704	0.95
654_D	661_V	0.703	0.95
595_V	598_Y	0.703	0.95
479_C	563_S	0.702	0.95
515_L	520_V	0.701	0.95
610_L	614_R	0.700	0.95
205_P	208_L	0.697	0.95
35_D	38_L	0.697	0.95
488_W	507_T	0.697	0.95
590_V	597_L	0.696	0.94
225_I	229_L	0.696	0.94
271_G	275_R	0.695	0.94
112_R	116_Y	0.695	0.94
275_R	450_E	0.694	0.94
590_V	601_P	0.694	0.94
667_H	670_E	0.692	0.94
201_L	648_V	0.691	0.94
193_T	197_A	0.691	0.94
107_L	111_R	0.690	0.94
630_R	637_G	0.689	0.94
150_P	154_T	0.688	0.94
660_E	665_A	0.688	0.94
105_N	108_A	0.687	0.94
523_V	532_K	0.686	0.94
126_A	131_P	0.686	0.94
57_L	62_A	0.683	0.94
619_G	631_G	0.683	0.94
287_D	422_H	0.682	0.94
618_D	621_V	0.680	0.94
251_L	318_K	0.679	0.94
192_M	195_P	0.678	0.94
192_M	200_T	0.678	0.94
158_V	163_L	0.677	0.94
279_E	446_S	0.677	0.94
220_A	228_E	0.676	0.94
647_K	652_L	0.675	0.94
335_N	339_N	0.675	0.94
527_M	535_V	0.675	0.94
408_L	412_E	0.674	0.93
261_L	304_L	0.674	0.93
36_L	167_T	0.674	0.93
127_E	131_P	0.673	0.93
253_A	256_T	0.672	0.93
307_A	311_L	0.672	0.93
305_V	448_I	0.670	0.93
145_Q	149_T	0.669	0.93
472_I	515_L	0.669	0.93
609_R	616_S	0.668	0.93
605_T	613_L	0.668	0.93
487_Y	557_V	0.666	0.93
625_K	631_G	0.666	0.93
109_A	112_R	0.665	0.93
182_L	231_A	0.665	0.93
363_Q	375_I	0.665	0.93
462_A	614_R	0.665	0.93
659_P	667_H	0.665	0.93
119_A	131_P	0.664	0.93
627_L	631_G	0.664	0.93
369_S	373_Q	0.663	0.93
223_R	229_L	0.663	0.93
272_A	448_I	0.662	0.93
631_G	636_L	0.661	0.93
49_H	54_G	0.659	0.93
590_V	595_V	0.658	0.93
653_R	656_A	0.656	0.93
74_S	79_R	0.656	0.93
252_S	312_R	0.656	0.93
531_E	534_A	0.655	0.92
626_D	629_I	0.655	0.92
66_G	69_L	0.655	0.92
622_I	626_D	0.653	0.92
630_R	634_E	0.652	0.92
606_A	612_V	0.652	0.92
474_R	564_L	0.651	0.92
220_A	226_L	0.650	0.92
280_I	283_D	0.649	0.92
167_T	203_R	0.648	0.92
644_A	651_L	0.648	0.92
651_L	655_Q	0.648	0.92
405_H	408_L	0.647	0.92
633_G	636_L	0.647	0.92
201_L	209_Q	0.647	0.92
137_G	142_P	0.646	0.92
107_L	110_G	0.646	0.92
311_L	341_F	0.646	0.92
54_G	57_L	0.645	0.92
237_L	240_R	0.645	0.92
357_G	360_R	0.644	0.92
489_V	565_M	0.644	0.92
644_A	649_A	0.642	0.92
225_I	653_R	0.641	0.92
115_A	133_Y	0.641	0.92
592_S	600_T	0.641	0.92
619_G	630_R	0.640	0.92
649_A	653_R	0.640	0.92
251_L	316_H	0.640	0.92
36_L	39_H	0.638	0.91
233_N	236_M	0.636	0.91
583_G	586_G	0.636	0.91
148_L	152_Y	0.636	0.91
663_R	671_R	0.635	0.91
567_I	613_L	0.635	0.91
152_Y	158_V	0.633	0.91
650_D	654_D	0.632	0.91
480_I	483_G	0.631	0.91
261_L	277_V	0.631	0.91
240_R	243_A	0.631	0.91
595_V	599_K	0.630	0.91
598_Y	610_L	0.628	0.91
152_Y	157_G	0.627	0.91
241_A	670_E	0.627	0.91
202_H	205_P	0.626	0.91
352_A	355_Q	0.626	0.91
485_Q	542_G	0.626	0.91
622_I	633_G	0.625	0.91
442_D	446_S	0.624	0.91
322_L	395_I	0.623	0.91
619_G	625_K	0.623	0.91
481_T	518_L	0.622	0.90
623_A	628_E	0.621	0.90
632_P	642_G	0.620	0.90
431_I	437_M	0.620	0.90
76_G	80_M	0.620	0.90
658_I	661_V	0.619	0.90
330_A	350_W	0.618	0.90
257_L	344_L	0.618	0.90
623_A	629_I	0.617	0.90
162_T	170_A	0.617	0.90
259_N	262_L	0.615	0.90
407_R	410_L	0.613	0.90
223_R	231_A	0.613	0.90
228_E	231_A	0.613	0.90
32_T	35_D	0.612	0.90
158_V	166_L	0.612	0.90
218_H	223_R	0.612	0.90
124_Y	128_M	0.610	0.90
620_F	631_G	0.608	0.89
191_M	194_L	0.607	0.89
569_N	572_R	0.607	0.89
254_N	260_K	0.607	0.89
113_V	117_G	0.606	0.89
619_G	626_D	0.606	0.89
53_I	92_L	0.604	0.89
179_I	186_E	0.604	0.89
181_E	194_L	0.603	0.89
225_I	228_E	0.603	0.89
249_Q	252_S	0.603	0.89
355_Q	367_I	0.602	0.89
326_T	380_A	0.601	0.89
635_L	639_R	0.601	0.89
27_K	155_T	0.601	0.89
462_A	598_Y	0.601	0.89
102_A	105_N	0.599	0.89
111_R	135_V	0.599	0.89
73_I	104_K	0.599	0.89
313_A	318_K	0.598	0.89
57_L	70_N	0.598	0.89
152_Y	171_L	0.598	0.89
221_Q	224_L	0.597	0.89
278_A	281_E	0.595	0.88
297_D	300_S	0.595	0.88
111_R	114_L	0.593	0.88
69_L	84_Q	0.593	0.88
200_T	204_P	0.592	0.88
436_A	440_Y	0.591	0.88
669_H	674_Q	0.591	0.88
33_V	37_L	0.589	0.88
591_A	599_K	0.589	0.88
194_L	202_H	0.589	0.88
203_R	208_L	0.589	0.88
604_K	617_N	0.588	0.88
602_L	606_A	0.587	0.88
486_A	564_L	0.587	0.88
167_T	174_L	0.585	0.88
186_E	189_Q	0.585	0.88
146_E	149_T	0.585	0.88
40_L	648_V	0.584	0.87
71_C	80_M	0.584	0.87
371_Q	375_I	0.583	0.87
122_G	130_H	0.583	0.87
369_S	372_V	0.582	0.87
162_T	165_K	0.582	0.87
624_Q	630_R	0.582	0.87
442_D	450_E	0.582	0.87
65_E	76_G	0.581	0.87
258_K	312_R	0.581	0.87
282_R	285_A	0.581	0.87
664_L	669_H	0.581	0.87
511_L	515_L	0.580	0.87
455_R	459_T	0.580	0.87
492_L	495_E	0.580	0.87
593_H	599_K	0.579	0.87
198_L	201_L	0.578	0.87
94_M	98_N	0.578	0.87
78_R	88_G	0.577	0.87
144_L	149_T	0.577	0.87
321_A	375_I	0.577	0.87
471_I	486_A	0.576	0.87
400_H	555_V	0.576	0.87
47_R	116_Y	0.576	0.87
48_T	51_Y	0.576	0.87
485_Q	545_H	0.576	0.87
107_L	113_V	0.576	0.87
45_E	151_V	0.575	0.87
152_Y	160_Q	0.575	0.87
233_N	237_L	0.575	0.87
451_L	454_G	0.574	0.87
667_H	674_Q	0.574	0.87
158_V	167_T	0.573	0.87
106_S	110_G	0.573	0.87
609_R	613_L	0.572	0.86
469_T	473_D	0.572	0.86
183_L	188_S	0.571	0.86
657_M	661_V	0.571	0.86
135_V	138_D	0.570	0.86
628_E	635_L	0.570	0.86
465_D	468_R	0.570	0.86
456_T	563_S	0.569	0.86
93_T	100_S	0.569	0.86
652_L	663_R	0.568	0.86
620_F	633_G	0.567	0.86
157_G	164_R	0.567	0.86
225_I	230_L	0.567	0.86
118_E	130_H	0.566	0.86
605_T	629_I	0.565	0.86
160_Q	166_L	0.565	0.86
230_L	233_N	0.564	0.86
488_W	566_I	0.563	0.86
53_I	87_D	0.563	0.86
179_I	182_L	0.562	0.85
123_K	129_I	0.562	0.85
159_K	172_D	0.561	0.85
31_H	36_L	0.561	0.85
476_H	480_I	0.561	0.85
620_F	628_E	0.561	0.85
403_G	407_R	0.561	0.85
432_P	436_A	0.561	0.85
65_E	68_V	0.559	0.85
286_L	289_P	0.558	0.85
281_E	308_L	0.558	0.85
46_D	49_H	0.558	0.85
623_A	633_G	0.557	0.85
67_E	72_N	0.557	0.85
459_T	462_A	0.557	0.85
353_G	380_A	0.557	0.85
52_P	62_A	0.557	0.85
68_V	85_I	0.557	0.85
452_P	462_A	0.556	0.85
160_Q	169_Q	0.556	0.85
157_G	167_T	0.555	0.85
307_A	336_N	0.555	0.85
482_E	590_V	0.554	0.85
115_A	128_M	0.554	0.85
229_L	646_F	0.554	0.85
255_D	258_K	0.554	0.85
68_V	78_R	0.553	0.85
206_P	210_L	0.553	0.85
229_L	233_N	0.552	0.84
61_Y	67_E	0.552	0.84
104_K	107_L	0.551	0.84
55_E	60_V	0.550	0.84
225_I	654_D	0.550	0.84
646_F	651_L	0.549	0.84
584_R	587_R	0.549	0.84
304_L	307_A	0.549	0.84
658_I	667_H	0.549	0.84
597_L	600_T	0.548	0.84
600_T	603_S	0.548	0.84
127_E	133_Y	0.548	0.84
282_R	286_L	0.547	0.84
351_L	367_I	0.547	0.84
671_R	674_Q	0.547	0.84
622_I	630_R	0.547	0.84
181_E	184_P	0.547	0.84
328_L	533_Q	0.546	0.84
335_N	338_R	0.546	0.84
272_A	279_E	0.545	0.84
629_I	633_G	0.544	0.84
464_P	467_R	0.542	0.83
132_E	135_V	0.542	0.83
319_Q	391_L	0.541	0.83
201_L	205_P	0.541	0.83
70_N	73_I	0.541	0.83
596_L	613_L	0.541	0.83
574_G	581_L	0.541	0.83
51_Y	62_A	0.540	0.83
129_I	136_Q	0.540	0.83
229_L	658_I	0.540	0.83
654_D	660_E	0.539	0.83
152_Y	163_L	0.539	0.83
657_M	664_L	0.539	0.83
621_V	627_L	0.539	0.83
655_Q	672_Y	0.538	0.83
44_Y	48_T	0.538	0.83
461_V	467_R	0.538	0.83
28_I	40_L	0.537	0.83
270_T	329_L	0.537	0.83
201_L	224_L	0.536	0.83
658_I	665_A	0.536	0.83
33_V	170_A	0.536	0.83
471_I	597_L	0.536	0.83
561_N	590_V	0.536	0.83
39_H	42_L	0.535	0.83
119_A	122_G	0.535	0.83
110_G	117_G	0.535	0.83
39_H	155_T	0.534	0.82
92_L	119_A	0.534	0.82
458_V	617_N	0.533	0.82
71_C	109_A	0.533	0.82
129_I	133_Y	0.532	0.82
172_D	188_S	0.532	0.82
470_D	477_H	0.532	0.82
445_T	450_E	0.532	0.82
392_A	422_H	0.531	0.82
480_I	544_L	0.531	0.82
188_S	191_M	0.531	0.82
117_G	128_M	0.529	0.82
328_L	489_V	0.529	0.82
254_N	258_K	0.529	0.82
105_N	109_A	0.528	0.82
192_M	209_Q	0.528	0.82
247_H	287_D	0.528	0.82
545_H	561_N	0.527	0.82
515_L	518_L	0.527	0.82
655_Q	666_R	0.526	0.82
62_A	66_G	0.526	0.82
107_L	133_Y	0.525	0.81
633_G	640_Q	0.525	0.81
507_T	511_L	0.525	0.81
655_Q	658_I	0.524	0.81
106_S	135_V	0.523	0.81
457_P	462_A	0.523	0.81
81_M	100_S	0.523	0.81
300_S	448_I	0.523	0.81
161_A	166_L	0.522	0.81
553_I	557_V	0.520	0.81
658_I	663_R	0.520	0.81
34_Q	40_L	0.520	0.81
333_H	376_V	0.520	0.81
221_Q	227_E	0.519	0.81
99_F	131_P	0.519	0.81
281_E	285_A	0.519	0.81
400_H	576_A	0.517	0.80
153_P	157_G	0.517	0.80
598_Y	606_A	0.517	0.80
523_V	553_I	0.517	0.80
407_R	413_K	0.516	0.80
162_T	167_T	0.516	0.80
220_A	223_R	0.516	0.80
380_A	401_R	0.516	0.80
632_P	644_A	0.515	0.80
270_T	332_Q	0.515	0.80
664_L	672_Y	0.515	0.80
191_M	197_A	0.515	0.80
152_Y	166_L	0.515	0.80
633_G	642_G	0.514	0.80
654_D	663_R	0.513	0.80
258_K	262_L	0.513	0.80
246_F	251_L	0.512	0.80
157_G	160_Q	0.511	0.80
647_K	650_D	0.511	0.80
188_S	192_M	0.511	0.80
597_L	601_P	0.511	0.80
614_R	618_D	0.510	0.80
57_L	61_Y	0.510	0.80
33_V	40_L	0.510	0.80
296_G	554_E	0.510	0.80
194_L	204_P	0.510	0.80
61_Y	116_Y	0.509	0.79
90_G	98_N	0.508	0.79
149_T	152_Y	0.508	0.79
463_I	470_D	0.508	0.79
103_M	107_L	0.508	0.79
347_E	372_V	0.508	0.79
244_Q	444_D	0.508	0.79
654_D	665_A	0.507	0.79
480_I	545_H	0.507	0.79
328_L	532_K	0.507	0.79
354_K	529_P	0.506	0.79
125_G	137_G	0.506	0.79
648_V	652_L	0.506	0.79
125_G	130_H	0.506	0.79
474_R	595_V	0.506	0.79
122_G	127_E	0.506	0.79
632_P	636_L	0.505	0.79
480_I	486_A	0.505	0.79
230_L	664_L	0.504	0.79
196_E	219_P	0.504	0.79
151_V	162_T	0.504	0.79
60_V	74_S	0.504	0.79
651_L	654_D	0.503	0.79
182_L	186_E	0.503	0.79
619_G	633_G	0.502	0.78
272_A	453_P	0.502	0.78
179_I	184_P	0.502	0.78
622_I	628_E	0.502	0.78
126_A	132_E	0.501	0.78
159_K	167_T	0.501	0.78
626_D	640_Q	0.501	0.78
409_A	414_G	0.501	0.78
394_V	421_P	0.500	0.78
514_A	517_E	0.500	0.78
61_Y	64_V	0.500	0.78

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1gm5A	1	0.8975	100	0.311	Contact Map
2eyqA	1	0.9495	100	0.474	Contact Map
4nhoA	1	0.5642	100	0.49	Contact Map
4pxaA	1	0.5859	100	0.495	Contact Map
2db3A	1	0.5786	100	0.501	Contact Map
4ljyA	1	0.6017	100	0.506	Contact Map
4d25A	1	0.5758	100	0.514	Contact Map
4c9bA	1	0.5426	100	0.514	Contact Map
3fmpB	1	0.3102	100	0.518	Contact Map
3mwyW	2	0.7778	100	0.521	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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